RYONG-WOON Shin 辛龍雲

… Alternative Names

SHIN Ryoung-Woon 辛龍雲

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Researcher Number	40271910
External Links
Affiliation (based on the past Project Information) *help	2007: Tohoku University, Graduate School of Medicine, Associate Professor 2004: 東北大学, 医学系研究科, 講師 1999 – 2004: school of medicine Lecturer 1996〜1197 Tohoku University, 大学院・医学系研究科, 講師 1996 – 1998: 東北大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Biological Sciences / Nerve anatomy/Neuropathology Except Principal Investigator Applied molecular and cellular biology / Nerve anatomy/Neuropathology
Keywords	Principal Investigator アルツハイマー病 / Alzheimer's disease / tau / Pin1 / C99 / APP / amyloid β / PHFtau / tau蛋白 / リン酸化蛋白 … More / COS7 cell / dephosphorylation / phosphorylation / 細胞質 / 小胞体 / Tau / Aβ / COS7細胞 / 脱リン酸化 / リン酸化 / βcleavage / αcleavage / γsecretase / βsecretase / αsecretase / アミロイド前駆体蛋白 / β切断 / α切断 / animal model / processing / transgenic mouse / amyloid precursor protein / presenilin 1 / 動物モデル / プロセッシング / トランスジェニック・マウス / アミロイド前駆蛋白 / プレセニリン / neurofibrillary tangles / トランスジェニック / タウ蛋白 / PHFτ / τ蛋白 / 神経原線維変化 / 酸化的ストレス / OXR蛋白 / 老化 / アルミニウム … More Except Principal Investigator Notch1 / Myc / Pin1 / アルツハイマー病 / Alzheimer''s disease / thymus / Amyloid / p53 / trans isomerase / peptidyl prolyl cis / Tau / リチウム / プルセニリン / ノックアウトマウス / 胸腺肥大 / 癌 / リン酸化 / tat-Pin1 / プロテオーム / mcl1 / stat3 / 胸腺 / アミロイド / P53 / プロリン異性化酵素 / トランスジェニックマウス / yeast two hybrid system / プレセニリン1 Less

Analysis of the stress resistance functions of Prolyl Isomerase Pin1
- Principal Investigator
  
  UCHIDA Takafumi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tohoku University
Roles of Aβ42 secreted in the lumen of the endoplasmic reticulum played in the disease course of Alzheimer'diseasePrincipal Investigator
- Principal Investigator
  
  SHIN Ryong-woon
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tohoku University
アルツハイマー病脳におけるリン酸化反応基質蛋白の動態とその病態に果たす役割Principal Investigator
- Principal Investigator
  
  辛龍雲
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Study of generation of Alzheimer's amyloid β peptidePrincipal Investigator
- Principal Investigator
  
  RYONG-WOON Shin
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tohoku University
老化脳およびアルツハイマー病脳特異的リン酸化反応基質蛋白の同定Principal Investigator
- Principal Investigator
  
  辛龍雲
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Production of transgenic mice expressing familial AD relevant genesPrincipal Investigator
- Principal Investigator
  
  SHIN Ryong-woon
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  TOHOKU UNIVERSITY
家族制アルツハイマー病原因遺伝子presenilin-1結合因子の探索
- Principal Investigator
  
  KITAMOTO Tetsuyuki
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tohoku University
A production of animal model for neurofibrillary tangles of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  SHIN Ryoung-Woon
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tohoku University

All 2008 2006 2005

All Journal Article

[Journal Article] Proly1 isomerase Pin1: New findings on post-translational modifications and physiological substrates in cancer, Alzheimer''s disease and asthma2008
- Author(s)
  Takahashi K, Uchida C, Shin RW, Shimazaki, K and Uchida T.
- Journal Title
  
  Cell and Mol Life Sci. 65
  
  Pages: 359-375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] 認知症のメカニズムに迫る Pinl とアルツハイマー病の病態2006
- Author(s)
  辛龍雲, et al.
- Journal Title
  
  化学と生物 44
  
  Pages: 447-452
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] 認知症のメカニズムに迫る Pin1とアルツハイマー病の病態2006
- Author(s)
  辛龍雲 , et. al.
- Journal Title
  
  「化学と生物」 44
  
  Pages: 447-452
- NAID
  10017994673
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Novel mechanism undering dementia-Pin1 and Alzheimer's disease2006
- Author(s)
  Shin RW, Akiyama H and uchida T
- Journal Title
  
  Chem and Biol (Japanese) 44
  
  Pages: 447-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Proly1 isomerase Pin1 facilitates production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein2005
- Author(s)
  Akiyama H, Shin R, Uchida C, Kitamoto T and UchidaT
- Journal Title
  
  Biochem Biophys Res Commun(Corrigendum; Nature(2007)446,342) 336
  
  Pages: 521-529
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Novel α-secretase cleavage of Alzheimer's amyloid β precursor protein in the endoplasmic reticulum of COS7 cells.2005
- Author(s)
  R-W Shin, T.C.Saido, M.Maeda, T.Kitamoto
- Journal Title
  
  Neurosci lett 376
  
  Pages: 14-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500225
[Journal Article] Novel α-secretase cleavage of Alzheimer's amyloid β precursorprotein in the endoplasmic reticulum of COS7 cells.2005
- Author(s)
  P-W Shin, T.C.Saido, M.Maeda, T.Kitamoto.
- Journal Title
  
  Neurosci lett 376
  
  Pages: 14-19
- Data Source
  KAKENHI-PROJECT-15500225

1. KITAMOTO Tetsuyuki (20192560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. UCHIDA Takafumi (80312239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. UCHIDA Chiyoko (80312776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 秋山弘匡 (40400254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 福本学 (60156809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 西森克彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

RYONG-WOON Shin 辛 龍雲

SHIN Ryoung-Woon 辛 龍雲

Research Projects

Research Products

Co-Researchers

Analysis of the stress resistance functions of Prolyl Isomerase Pin1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of Aβ42 secreted in the lumen of the endoplasmic reticulum played in the disease course of Alzheimer'diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アルツハイマー病脳におけるリン酸化反応基質蛋白の動態とその病態に果たす役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of generation of Alzheimer's amyloid β peptidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

老化脳およびアルツハイマー病脳特異的リン酸化反応基質蛋白の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Production of transgenic mice expressing familial AD relevant genesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

家族制アルツハイマー病原因遺伝子presenilin-1結合因子の探索

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A production of animal model for neurofibrillary tangles of Alzheimer's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Proly1 isomerase Pin1: New findings on post-translational modifications and physiological substrates in cancer, Alzheimer''s disease and asthma2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] 認知症のメカニズムに迫る Pinl とアルツハイマー病の病態2006

Author(s)

Journal Title

Data Source

[Journal Article] 認知症のメカニズムに迫る Pin1とアルツハイマー病の病態2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Novel mechanism undering dementia-Pin1 and Alzheimer's disease2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Proly1 isomerase Pin1 facilitates production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Novel α-secretase cleavage of Alzheimer's amyloid β precursor protein in the endoplasmic reticulum of COS7 cells.2005

Author(s)

RYONG-WOON Shin 辛龍雲

SHIN Ryoung-Woon 辛龍雲