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hiraoka nobuyoshi  平岡 伸介

ORCIDConnect your ORCID iD *help
… Alternative Names

HIRAOKA Nobuyoshi  平岡 伸介

平岡 伸介  ヒラオカ ノブヨシ

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Researcher Number 40276217
Affiliation (Current) 2025: 国立研究開発法人国立がん研究センター, 中央病院, 科長
Affiliation (based on the past Project Information) *help 2015 – 2024: 国立研究開発法人国立がん研究センター, 中央病院, 科長
2023: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長
2017: 国立がん研究センター, ユニット長
2017: 国立がん研究センター中央病院, 病理科・研究所分子病理分野
2015: 国立研究開発法人国立がん研究センター, その他部局等, その他 … More
2014: 独立行政法人国立がん研究センター, その他部局等, その他
2014: 独立行政法人国立がん研究センター, 中央病院, 科長
2013: 独立行政法人国立がん研究センター, 中央病院, 医長
2010 – 2012: 独立行政法人国立がん研究センター, 研究所, ユニット長
2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所病理部, 室長
2005: 国立がんセンター(研究所及び東病院臨床開発センター), 病理部, 室長
2004: 国立がんセンター(研究所), 研究所病理部, 室長
1997: 東海大, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related / Experimental pathology / Basic Section 50010:Tumor biology-related / Human pathology / Human pathology
Except Principal Investigator
Human pathology / Basic Section 49020:Human pathology-related / Biological pharmacy / Laboratory animal science / Tumor biology / Surgical dentistry
Keywords
Principal Investigator
膵がん / がん微小環境 / 神経 / 免疫微小環境 / 腫瘍免疫 / 制御性T細胞 / 胆管がん / 免疫環境 / 血管 / 末梢神経 … More / 神経系 / 免疫系 / 免疫 / 神経束 / 微小環境 / 3次リンパ装置 / EBI3 / 転写因子FOXP3 / リンパ球抑制活性 / 免疫学 / 病理学 / がん / 多段階発癌 / 樹状細胞 / 膵管内粘液乳頭腫瘍 / 抗腫瘍免疫 / 多段階発がん … More
Except Principal Investigator
病理学 / 免疫微小環境 / 膵癌 / がん / 抗ウイルス剤 / Sustained Viral Response / Direct acting Antivirals / 肝細胞癌 / CD8 / 肝炎ウイルス / 肝癌 / 転移 / 発がん / innate lymphoid cells / 腫瘍免疫 / Innate lymphoid cells / pancreatic cancer / セレクチン / フコース転移酵素 / 糖鎖 / 免疫学 / 薬学 / バイオマーカー / がん転移 / 大腸がん / シアリルルイスX / 抗糖鎖抗体 / がんの免疫微小環境 / 内皮細胞 / がん微小環境 / 血管内皮細胞 / 膵がん / 上皮間葉転換 / インタラクトーム / インタラクト―ム / PDX / ZNF185 / 遺伝子 / p53 / PHLDA3遺伝子 / がん遺伝子Akt / がん抑制遺伝子 / PHLDA3 / Akt / 神経内分泌腫瘍 / 抗体スクリーニング / リン酸化タンパク質発現プロファイル / 逆相タンパク質マイクロアレイ / 舌扁平上皮がん / キノームプロファイル / 抗体ライブラリー / 組織マイクロアレイ / 舌がん / 口腔扁平上皮がん / 抗体基盤プロテオミクス / 分子標的治療 / 口腔がん / キノーム Less
  • Research Projects

    (14 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (29 People)
  •  Vascular roles in tumor immune microenvironment of pancreatic and biliary cancersPrincipal Investigator

    • Principal Investigator
      平岡 伸介
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      National Cancer Center Japan
  •  Biological roles of neural system in pancreatic tumor immune microenvironmentPrincipal Investigator

    • Principal Investigator
      Hiraoka Nobuyoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      National Cancer Center Japan
  •  Pathological investigation of microenvironment in the liver cancer treated by direct anti-viral drugs

    • Principal Investigator
      Aishima Shinichi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Saga University
  •  Formation and maintenance of tertiary lymphoid organsPrincipal Investigator

    • Principal Investigator
      Hiraoka Nobuyoshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      National Cancer Center Japan
  •  Functional analysis of PHLDA3, a repressor of Akt, to elucidate the mechanism of neuroendocrine tumor development

    • Principal Investigator
      Ohki Rieko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      National Cancer Center Japan
  •  The analyses of epithelial-mesenchymal transition associating with LIM protein family ZNF185 using in vivo liver metastasis mouse models of the human pancreas cancer.

    • Principal Investigator
      FURUKAWA Daisuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokai University
  •  Role and function control of vascular endothelial cells in pancreatic cancer immune microenvironment

    • Principal Investigator
      Ishikawa(Ino) Yoshinori
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Japan
  •  Novel anti-carbohydrate antibodies reveal the role of glycans in tumor malignancy and their use as tumor biomarkers

    • Principal Investigator
      Kawashima Hiroto
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  The role of innate lymphoid cells in tumor immunity of pancreatic cancer

    • Principal Investigator
      Yoshida Hiroshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Japan
  •  Molecular mechanisms to form antitumor immune microenvironmentPrincipal Investigator

    • Principal Investigator
      Hiraoka Nobuyoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      National Cancer Center Japan
  •  Development of novel molecular targets for oral cancer with kinome profile by antibody-based proteomics

    • Principal Investigator
      Kazufumi Honda
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      National Cancer Center Japan
  •  Biological function and characteristics of human regulatory T cells : A new molecular pathwayPrincipal Investigator

    • Principal Investigator
      HIRAOKA Nobuyoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  多段階発癌過程における抗腫瘍免疫応答の変化とその機構の解明Principal Investigator

    • Principal Investigator
      平岡 伸介
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  ヒト生殖細胞の分化・腫瘍化に関連する3種の新たな抗原分子の単離・同定とその機能Principal Investigator

    • Principal Investigator
      平岡 伸介
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Correlation of Vein-Rich Tumor Microenvironment of Intrahepatic Cholangiocarcinoma With Tertiary Lymphoid Structures and Patient Outcome2024

    • Author(s)
      Doi N, Ino Y, Fuse M, Esaki M, Shimada K, Hiraoka N
    • Journal Title

      Mod Pathol

      Volume: 37 Issue: 2 Pages: 100401-100401

    • DOI

      10.1016/j.modpat.2023.100401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07139
  • [Journal Article] Novel Insights Into Immunohistochemical Analysis For Acinar Cell Neoplasm of The Pancreas: Carboxypeptidase A2, Carboxypeptidase A1, and Glycoprotein 2.2023

    • Author(s)
      Ishimoto-Namiki U, Ino Y, Esaki M, Shimada K, Saruta M, Hiraoka N.
    • Journal Title

      Am J Surg Pathol.

      Volume: 47 Issue: 5 Pages: 525-534

    • DOI

      10.1097/pas.0000000000002024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07139
  • [Journal Article] Novel insights into the intraepithelial spread of extrahepatic cholangiocarcinoma: clinicopathological study of 382 cases on extrahepatic cholangiocarcinoma2023

    • Author(s)
      Nagashima D, Esaki M, Nara S, Ban D, Takamoto T, Mizui T, Shimada K, Hiraoka N
    • Journal Title

      Front Oncol

      Volume: 13 Pages: 1216097-1216097

    • DOI

      10.3389/fonc.2023.1216097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07139
  • [Journal Article] Neoadjuvant therapy alters the collagen architecture of pancreatic cancer tissue via Ephrin-A5.2022

    • Author(s)
      Nakajima K, Ino Y, Naito C, Nara S, Shimasaki M, Ishimoto U, Iwasaki T, Doi N, Esaki M, Kishi Y, Shimada K, Hiraoka N.
    • Journal Title

      Br J Cancer

      Volume: 126 Issue: 4 Pages: 628-639

    • DOI

      10.1038/s41416-021-01639-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07139
  • [Journal Article] Novel insights into immunohistochemical analysis for diagnosing serous neoplasm of the pancreas: aquaporin 1, stereocilin, and transmembrane protein 255B.2021

    • Author(s)
      Watase C, Fuse M, Ino Y, Naito C, Hiraoka N.
    • Journal Title

      Histopathology

      Volume: 79 Issue: 5 Pages: 872-879

    • DOI

      10.1111/his.14456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07139
  • [Journal Article] Association between the expression of core 3 synthase and survival outcomes of patients with cholangiocarcinoma.2021

    • Author(s)
      Boottanun P, Ino Y, Shimada K, Hiraoka N, Angata K, Narimatsu H.
    • Journal Title

      Oncol Lett.

      Volume: 22 Issue: 5 Pages: 760-760

    • DOI

      10.3892/ol.2021.13021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07139
  • [Journal Article] Expression of classical HLA class I antigens, HLA-E, and HLA-G is adversely prognostic in pancreatic cancer patients.2020

    • Author(s)
      Hiraoka N, Ino Y, Hori S, Yamazaki-Itoh R, Naito C, Shimasaki M, Esaki M, Nara S, Kishi Y, Shimada K, Nakamura N, Torigoe T, Heike Y.
    • Journal Title

      Cancer Sci.

      Volume: in press Issue: 8 Pages: 3057-3070

    • DOI

      10.1111/cas.14514

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07008
  • [Journal Article] Details of human epidermal growth factor receptor 2 status in 454 cases of biliary tract cancer.2020

    • Author(s)
      Hiraoka N, Nitta H, Ohba A, Yoshida H, Morizane C, Okusaka T, Nara S, Esaki M, Kishi Y, Shimada K.
    • Journal Title

      Hum Pathol

      Volume: 105 Issue: 1 Pages: 9-19

    • DOI

      10.1080/2162402x.2020.1838812

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07008
  • [Journal Article] Clinicopathological significance of core 3 O-glycan synthetic enzyme, β1,3-N-acetylglucosaminyltransferase 6 in pancreatic ductal adenocarcinoma.2020

    • Author(s)
      Doi N, Ino Y, Angata K, Shimada K, Narimatsu H, Hiraoka N.
    • Journal Title

      PLoS One

      Volume: 15 Issue: 11 Pages: e0242851-e0242851

    • DOI

      10.1371/journal.pone.0242851

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07008
  • [Journal Article] Reduction of intrapancreatic neural density in cancer tissue predicts poorer outcome in pancreatic ductal carcinoma.2019

    • Author(s)
      Iwasaki T, Hiraoka N, Ino Y, Nakajima K, Kishi Y, Nara S, Esaki M, Shimada K, Katai H.
    • Journal Title

      Cancer Sci.

      Volume: 110 Issue: 4 Pages: 1491-1502

    • DOI

      10.1111/cas.13975

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07008
  • [Journal Article] Reliable evaluation of tumor-infiltrating lymphocytes in pancreatic cancer tissue biopsies.2019

    • Author(s)
      Ino Y, Oguro S, Yamazaki-Itoh R, Hori S, Shimada K, Hiraoka N
    • Journal Title

      Oncotarget

      Volume: 10 Issue: 10 Pages: 1149-1159

    • DOI

      10.18632/oncotarget.26646

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07008
  • [Journal Article] Reduction of intrapancreatic neural density in cancer tissue predicts poorer outcome in pancreatic ductal carcinoma.2019

    • Author(s)
      Iwasaki T, Hiraoka N, Ino Y, Nakajima K, Kishi Y, Nara S, Esaki M, Shimada K, Katai H.
    • Journal Title

      Cancer Sci

      Volume: 110 Pages: 1491-1502

    • Data Source
      KAKENHI-PROJECT-16K08663
  • [Journal Article] Reliable evaluation of tumor-infiltrating lymphocytes in pancreatic cancer tissue biopsies.2019

    • Author(s)
      Ino Y, Oguro S, Yamazaki-Itoh R, Hori S, Shimada K, Hiraoka N.
    • Journal Title

      Oncotarget

      Volume: 10 Pages: 1149-1159

    • Data Source
      KAKENHI-PROJECT-16K08663
  • [Journal Article] Clinicopathologic Association and Prognostic Value of Microcystic, Elongated, and Fragmented (MELF) Pattern in Endometrial Endometrioid Carcinoma.2017

    • Author(s)
      Kihara A, Yoshida H, Watanabe R, Takahashi K, Kato T, Ino Y, Kitagawa M, Hiraoka N.
    • Journal Title

      Am J Surg Pathol

      Volume: 41(7) Pages: 896-905

    • Data Source
      KAKENHI-PROJECT-16K08663
  • [Journal Article] An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation-Negative Pancreatic Ductal Adenocarcinoma.2017

    • Author(s)
      Shimada Y, Kohno T, Ueno H, Ino Y, Hayashi H, Nakaoku T, Sakamoto Y, Kondo S, Morizane C, Shimada K, Okusaka T, Hiraoka N.
    • Journal Title

      Oncologist

      Volume: 22(2) Pages: 158-164

    • Data Source
      KAKENHI-PROJECT-16K08663
  • [Journal Article] Strong antitumor efficacy of a pancreatic tumor-targeting oncolytic adenovirus for neuroendocrine tumors.2017

    • Author(s)
      Yamamoto Y, Nagasato M, Rin Y, Henmi M, Ino Y, Yachida S, Ohki R, Hiraoka N, Tagawa M, Aoki K.
    • Journal Title

      Cancer Med.

      Volume: 6(10) Pages: 2385-2397

    • Data Source
      KAKENHI-PROJECT-16K08663
  • [Journal Article] Plasma membrane expression of ZNF185 is a prognostic factor in pancreatic ductal carcinoma2017

    • Author(s)
      Furukawa Daisuke、Chijiwa Tsuyoshi、Matsuyama Masahiro、Mukai Masaya、Matsuo Ei-Ichi、Nishimura Osamu、Kawai Kenji、Suemizu Hiroshi、Nakagohri Toshio、Ozawa Soji、Shimada Kazuaki、Hiraoka Nobuyoshi、Nakamura Masato
    • Journal Title

      Oncology Letters

      Volume: 14 Issue: 3 Pages: 3633-3640

    • DOI

      10.3892/ol.2017.6633

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07096
  • [Journal Article] Tumor-associated CD204+ M2 macrophages are unfavorable prognostic indicators in uterine cervical adenocarcinoma.2017

    • Author(s)
      Kawachi A, Yoshida H, Kitano S, Ino Y, Kato T, Hiraoka N.
    • Journal Title

      Cancer Sci

      Volume: 109(3) Pages: 863-870

    • Data Source
      KAKENHI-PROJECT-16K08663
  • [Journal Article] CIC-rearranged Sarcomas: A Study of 20 Cases and Comparisons With Ewing Sarcomas2016

    • Author(s)
      Yoshida A, Goto K, Kodaira M, Kobayashi E, Kawamoto H, Mori T, Yoshimoto S, Endo O, Kodama N, Kushima R, Hiraoka N, Motoi T, Kawai A.
    • Journal Title

      Am J Surg Pathol.

      Volume: 40 Issue: 3 Pages: 313-23

    • DOI

      10.1097/pas.0000000000000570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460463, KAKENHI-PROJECT-15K19065, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-25460448
  • [Journal Article] A significant subgroup of resectable gallbladder cancer patients has an HER2 positive status.2016

    • Author(s)
      Yoshida H, Shimada K, Kosuge T, Hiraoka N
    • Journal Title

      Virchows Arch.

      Volume: Apr;468(4): Issue: 4 Pages: 431-9

    • DOI

      10.1007/s00428-015-1898-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] Clinical significance of tumor-infiltrating immune cells focusing on BTLA and Cbl-b in patients with gallbladder cancer.2015

    • Author(s)
      Oguro S, Ino Y, Shimada K, Hatanaka Y, Matsuno Y, Esaki M, Nara S, Kishi Y, Kosuge T, Hiraoka N.
    • Journal Title

      Cancer Sci

      Volume: Dec;106(12) Issue: 12 Pages: 1750-60

    • DOI

      10.1111/cas.12825

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-24590674, KAKENHI-PROJECT-25460486
  • [Journal Article] ACTN4 copy number increase as a predictive biomarker for chemoradiotherapy of locally advanced pancreatic cancer.2015

    • Author(s)
      Watanabe T, Ueno H, Watabe Y, Hiraoka N, Morizane C, Itami J, Okusaka T, Miura N, Kakizaki T , Kakuya T, Kamita M, Tsuchida A, Nagakawa Y, Wilber H, Yamada T and Honda K
    • Journal Title

      Br J Cancer

      Volume: Feb 17;112(4) Issue: 4 Pages: 704-13

    • DOI

      10.1038/bjc.2014.623

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-25670868
  • [Journal Article] TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast.2015

    • Author(s)
      Yoshida M, Ogawa R, Yoshida H, Maeshima A, Kanai Y, Kinoshita T, Hiraoka N, Sekine S.
    • Journal Title

      Br J Cancer

      Volume: Oct 20;113(8) Issue: 8 Pages: 1244-8

    • DOI

      10.1038/bjc.2015.326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] Intratumoral tertiary lymphoid organ is a favorable prognosticator in patients with pancreatic cancer.2015

    • Author(s)
      Hiraoka N, Ino Y, Yamazaki-Itoh R, Kanai Y, Kosuge T, Shimada K.
    • Journal Title

      Br J Cancer

      Volume: 112 Issue: 11 Pages: 1782-90

    • DOI

      10.1038/bjc.2015.145

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460486
  • [Journal Article] Potential diagnostic biomarkers: differential expression of LMP2/β1i and cyclin B1 in human uterine leiomyosarcoma.2014

    • Author(s)
      Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Sudo T, Ishiko O, Yaegashi N, Aburatani H, Konishi I.
    • Journal Title

      Tumori

      Volume: Jul-Aug;100(4):

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.2014

    • Author(s)
      Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, Tycko B,Tsukada T, Kanai Y, Sumi S, Namiki H, Taya Y, Shibata T, Nakagama H.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: Jun 10;111(23) Issue: 23

    • DOI

      10.1073/pnas.1319962111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-26430133, KAKENHI-PROJECT-26462053
  • [Journal Article] Twenty-six Cases of Advanced Ampullary Adenocarcinoma2014

    • Author(s)
      Shoji H, Morizane C, Hiraoka N, Kondo S, Ueno H, Ohno I, Shimizu S, Mitsunaga
    • Journal Title

      Jpn J Clin Oncol.

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] Histopathological characteristics of hypervascular cholangiocellular carcinoma as an early stage of cholangiocellular carcinoma.2014

    • Author(s)
      Sato Y, Ojima H, Onaya H, Mori T, Hiraoka N, Kishi Y, Nara S, Esaki M, Shimada
    • Journal Title

      Hepatol Res.

      Volume: Sept 6 Issue: 11 Pages: 1119-1129

    • DOI

      10.1111/hepr.12236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518, KAKENHI-PROJECT-25670868
  • [Journal Article] Early venous return in hepatic angiomyolipoma due to an intratumoral structure resembling an arteriovenous fistula.2013

    • Author(s)
      Iwao Y, Ojima H, Onaya H, Sakamoto Y, Kishi Y, Nara S, Esaki M, Mizuguchi Y, Ushigome M, Asahina D, Hiraoka N, Shimada K, Kosuge T, Kanai Y.
    • Journal Title

      Hepatol Res.

      Volume: May 17 Issue: 6 Pages: 700-706

    • DOI

      10.1111/hepr.12163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518
  • [Journal Article] Bile duct carcinoma involving the common channel associated with pancreaticobiliary maljunction shows an extension pattern similar to ductal carcinoma of the pancreas.2013

    • Author(s)
      Yoshida N, Esaki M, Kishi Y, Shimada K, Ojima H, Kanai Y, Hiraoka N.
    • Journal Title

      Pathol Int

      Volume: Aug;63(8): Issue: 8 Pages: 415-8

    • DOI

      10.1111/pin.12085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518
  • [Journal Article] Pancreatic intraglandular metastasis predicts poorer outcome in postoperative patients with pancreatic ductal carcinoma.2013

    • Author(s)
      Oguro S, Shimada K, Ino Y, Esaki M, Nara S, Kishi Y, Kosuge T, Kanai Y, Hiraoka N.
    • Journal Title

      Am J Surg Pathol.

      Volume: Jul;37(7): Issue: 7 Pages: 1030-8

    • DOI

      10.1097/pas.0b013e3182834d22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518
  • [Journal Article] Gemcitabine in patients with intraductal papillary mucinous neoplasm with an associated invasive carcinoma of the pancreas.2013

    • Author(s)
      Otsuka T, Morizane C, Nara S, Ueno H, Kondo S, Shimada K, Kosuge T, Ikeda M, Hiraoka N, Okusaka T
    • Journal Title

      Pancreas.

      Volume: Jul;42(5) Issue: 5 Pages: 889-892

    • DOI

      10.1097/mpa.0b013e3182826f1f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer.2013

    • Author(s)
      : Ino Y, Yamazaki-Itoh R, Shimada K, Iwasaki M, Kosuge T, Kanai Y, Hiraoka N.
    • Journal Title

      Br J Cancer.

      Volume: Mar 5;108(4) Issue: 4 Pages: 914-23

    • DOI

      10.1038/bjc.2013.32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms.2013

    • Author(s)
      Nishikawa G, Sekine S, Ogawa R, Matsubara A, Mori T, Taniguchi H, Kushima R, Hiraoka N, Tsuta K, Tsuda H, Kanai Y.
    • Journal Title

      Br J Cancer.

      Volume: Mar 5;108(4): Issue: 4 Pages: 951-8

    • DOI

      10.1038/bjc.2013.47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-25670868
  • [Journal Article] High levels of FOXP3⁺ regulatory T cells in gastric MALT lymphoma predict responsiveness to Helicobacter pylori eradication.2013

    • Author(s)
      Iwaya Y, Kobayashi M, Momose M, Hiraoka N, Sakai Y, Akamatsu T, Tanaka E, Ohtani H, Fukuda M, Nakayama J.
    • Journal Title

      Helicobacter.

      Volume: Oct;18(5) Issue: 5 Pages: 356-62

    • DOI

      10.1111/hel.12051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-24590410
  • [Journal Article] Yoshida T, Saeki N.Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis2012

    • Author(s)
      Ono H, Hiraoka N, Lee YS, Woo SM, Lee WJ, Choi IJ, Saito A, Yanagihara K, Kanai Y, Ohnami S, Chiwaki F, Sasaki H, Sakamoto H, Yoshida T, Saeki N
    • Journal Title

      Genes Chromosomes Cancer.

      Volume: 51(1) Pages: 30-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in the early intraepithelial stages of human pancreatic carcinogenesis.2011

    • Author(s)
      Hiraoka N, et al.
    • Journal Title

      Gastroenterology

      Volume: 140 Pages: 310-321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590451
  • [Journal Article] CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in the early intraepithelial stages of human pancreatic carcinogenesis2011

    • Author(s)
      Hiraoka N. Yamazaki-Itoh R. Ino Y., et al
    • Journal Title

      Gastroenterology

      Volume: 140 Issue: 1 Pages: 310-321

    • DOI

      10.1053/j.gastro.2010.10.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590451
  • [Journal Article] Intrapancreatic nerve invasion as a predictor for recurrence after pancreaticoduodenectomy in patients with invasive ductal carcinoma of the pancreas2011

    • Author(s)
      Shimada K, Nara S, Esaki M, Sakamoto Y, Kosuge T, Hiraoka N
    • Journal Title

      Pancreas.

      Volume: 40(3) Pages: 464-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] Macrophage-capping protein as a tissue biomarker for prediction of response to gemcitabine treatment and prognosis in cholangiocarcinoma2011

    • Author(s)
      Morofuji N, Ojima H, Onaya H, Okusaka T, Shimada K, Sakamoto Y, Esaki M, Nara S, Kosuge T, Asahina D, Ushigome M, Hiraoka N, Nagino M, Kondo T
    • Journal Title

      J Proteomics.

      Volume: 75(5) Pages: 1577-1589

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469
  • [Journal Article] Tumor necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation2010

    • Author(s)
      Hiraoka N. Ino Y. Sekine S., et al
    • Journal Title

      Br J Cancer

      Volume: 103 Issue: 7 Pages: 1057-65

    • DOI

      10.1038/sj.bjc.6605854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590451
  • [Journal Article] Tumor necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation.2010

    • Author(s)
      Hiraoka N, et al.
    • Journal Title

      Br.J.Cancer

      Volume: 103 Pages: 1057-1065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590451
  • [Journal Article] Tumor-infiltrating lymphocytes and hepatocellular carcinoma : Molecular biology2010

    • Author(s)
      Hiraoka N
    • Journal Title

      Int J Clin Oncol

      Volume: 6 Issue: 6 Pages: 544-51

    • DOI

      10.1007/s10147-010-0130-1

    • NAID

      10027665099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590451
  • [Presentation] How to evaluate tumor-infiltrating immune cells in biopsied pancreatic cancer tissues2017

    • Author(s)
      Yoshinori Ino, Rie Yamazaki-Itoh, Seiji Oguro, Shutaro Hori, Kazuaki Shimada,Nobuyoshi Hiraoka
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-16K08663
  • [Presentation] Zinc finger protein 185 is a key molecule of liver metastasis in colon cancer.2016

    • Author(s)
      Furukawa D, Chijiwa T, Matsuyama M, Mukai M, Matsuo E, Nishimura O, Kawai K, Suemizu H, Nakagohri T, Yasuda S, Shimada K, Hiraoka N, Nakamura M.
    • Organizer
      AACR Anual Meeting 2016
    • Place of Presentation
      Ernest N. Morial Convention Center New Orleans
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07096
  • 1.  ISHIKAWA Yoshinori (90291137)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 2.  Kazufumi Honda (10260936)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  MORI Taisuke (00296708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  Sekine Shigeki (10321879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  WATABE Yukio (50733490)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  IZUMO Toshiyuki (80322709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Ohki Rieko (70356252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  FURUKAWA Daisuke (70459478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  NAKAMURA Masato (00164335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  Kawashima Hiroto (50260336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HIRAKAWA Jotaro (30609160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Yoshida Hiroshi (70750751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Aishima Shinichi (70346774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  下重 美紀 (00392340)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  八木原 一博 (00538126)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  小嶋 基寛 (30338470)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  森実 千種 (50501871)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  山田 正三 (80260131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  千々和 剛 (70642180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 20.  河村 大輔 (10776082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  鈴木 涼平 (30621809)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  中嶋 幸生 (80785775)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  吉田 裕樹 (40260715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  能城 浩和 (90301340)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  杉町 圭史 (90452763)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  関根 圭輔 (00323569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  青木 一教 (60270675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  YAMAZAKI Rie
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 29.  Yoshimoto Seiichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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