HIRAOKA Nobuyoshi 平岡伸介

… Alternative Names

平岡伸介ヒラオカノブヨシ

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Researcher Number	40276217
Affiliation (Current)	2023: 国立研究開発法人国立がん研究センター, 中央病院, 科長
Affiliation (based on the past Project Information) *help	2015 – 2021: 国立研究開発法人国立がん研究センター, 中央病院, 科長 2017: 国立がん研究センター, ユニット長 2017: 国立がん研究センター中央病院, 病理科・研究所分子病理分野 2015: 国立研究開発法人国立がん研究センター, その他部局等, その他 2014: 独立行政法人国立がん研究センター, その他部局等, その他 … More 2014: 独立行政法人国立がん研究センター, 中央病院, 科長 2013: 独立行政法人国立がん研究センター, 中央病院, 医長 2010 – 2012: 独立行政法人国立がん研究センター, 研究所, ユニット長 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所病理部, 室長 2005: 国立がんセンター(研究所及び東病院臨床開発センター), 病理部, 室長 2004: 国立がんセンター(研究所), 研究所病理部, 室長 1997: 東海大, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 50010:Tumor biology-related / Basic Section 49020:Human pathology-related / Human pathology / Human pathology Except Principal Investigator Human pathology / Basic Section 49020:Human pathology-related / Biological pharmacy / Laboratory animal science / Tumor biology / Surgical dentistry
Keywords	Principal Investigator 膵がん / 神経 / 腫瘍免疫 / 制御性T細胞 / 神経系 / がん微小環境 / 免疫 / 神経束 / 微小環境 / 3次リンパ装置 … More / 免疫微小環境 / EBI3 / 転写因子FOXP3 / リンパ球抑制活性 / 免疫学 / 病理学 / がん / 多段階発癌 / 樹状細胞 / 膵管内粘液乳頭腫瘍 / 抗腫瘍免疫 / 多段階発がん … More Except Principal Investigator 病理学 / 免疫微小環境 / 膵癌 / がん / 抗ウイルス剤 / Sustained Viral Response / Direct acting Antivirals / 肝癌 / 肝炎ウイルス / 肝細胞癌 / CD8 / 転移 / 発がん / innate lymphoid cells / 腫瘍免疫 / Innate lymphoid cells / pancreatic cancer / セレクチン / フコース転移酵素 / 糖鎖 / 免疫学 / 薬学 / バイオマーカー / がん転移 / 大腸がん / シアリルルイスX / 抗糖鎖抗体 / がんの免疫微小環境 / 内皮細胞 / がん微小環境 / 血管内皮細胞 / 膵がん / 上皮間葉転換 / インタラクトーム / インタラクト―ム / PDX / ZNF185 / 遺伝子 / p53 / PHLDA3遺伝子 / がん遺伝子Akt / がん抑制遺伝子 / PHLDA3 / Akt / 神経内分泌腫瘍 / 抗体スクリーニング / リン酸化タンパク質発現プロファイル / 逆相タンパク質マイクロアレイ / 舌扁平上皮がん / キノームプロファイル / 抗体ライブラリー / 組織マイクロアレイ / 舌がん / 口腔扁平上皮がん / 抗体基盤プロテオミクス / 分子標的治療 / 口腔がん / キノーム Less

Biological roles of neural system in pancreatic tumor immune microenvironmentPrincipal Investigator
- Principal Investigator
  
  平岡伸介
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
直接抗ウイルス剤によるウイルス排除後肝癌における免疫微小環境の病理学的研究
- Principal Investigator
  
  相島慎一
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Saga University
Formation and maintenance of tertiary lymphoid organsPrincipal Investigator
- Principal Investigator
  
  Hiraoka Nobuyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cancer Center Japan
Functional analysis of PHLDA3, a repressor of Akt, to elucidate the mechanism of neuroendocrine tumor development
- Principal Investigator
  
  Ohki Rieko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan
The analyses of epithelial-mesenchymal transition associating with LIM protein family ZNF185 using in vivo liver metastasis mouse models of the human pancreas cancer.
- Principal Investigator
  
  FURUKAWA Daisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokai University
Role and function control of vascular endothelial cells in pancreatic cancer immune microenvironment
- Principal Investigator
  
  Ishikawa(Ino) Yoshinori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Japan
Novel anti-carbohydrate antibodies reveal the role of glycans in tumor malignancy and their use as tumor biomarkers
- Principal Investigator
  
  Kawashima Hiroto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
The role of innate lymphoid cells in tumor immunity of pancreatic cancer
- Principal Investigator
  
  Yoshida Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Japan
Molecular mechanisms to form antitumor immune microenvironmentPrincipal Investigator
- Principal Investigator
  
  Hiraoka Nobuyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Japan
Development of novel molecular targets for oral cancer with kinome profile by antibody-based proteomics
- Principal Investigator
  
  Kazufumi Honda
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  National Cancer Center Japan
Biological function and characteristics of human regulatory T cells : A new molecular pathwayPrincipal Investigator
- Principal Investigator
  
  HIRAOKA Nobuyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
多段階発癌過程における抗腫瘍免疫応答の変化とその機構の解明Principal Investigator
- Principal Investigator
  
  平岡伸介
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ヒト生殖細胞の分化・腫瘍化に関連する3種の新たな抗原分子の単離・同定とその機能Principal Investigator
- Principal Investigator
  
  平岡伸介
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Neoadjuvant therapy alters the collagen architecture of pancreatic cancer tissue via Ephrin-A5.2022
- Author(s)
  Nakajima K, Ino Y, Naito C, Nara S, Shimasaki M, Ishimoto U, Iwasaki T, Doi N, Esaki M, Kishi Y, Shimada K, Hiraoka N.
- Journal Title
  
  Br J Cancer
  
  Volume: 126 Issue: 4 Pages: 628-639
- DOI
  10.1038/s41416-021-01639-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07139
[Journal Article] Novel insights into immunohistochemical analysis for diagnosing serous neoplasm of the pancreas: aquaporin 1, stereocilin, and transmembrane protein 255B.2021
- Author(s)
  Watase C, Fuse M, Ino Y, Naito C, Hiraoka N.
- Journal Title
  
  Histopathology
  
  Volume: 79 Issue: 5 Pages: 872-879
- DOI
  10.1111/his.14456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07139
[Journal Article] Association between the expression of core 3 synthase and survival outcomes of patients with cholangiocarcinoma.2021
- Author(s)
  Boottanun P, Ino Y, Shimada K, Hiraoka N, Angata K, Narimatsu H.
- Journal Title
  
  Oncol Lett.
  
  Volume: 22 Issue: 5 Pages: 760-760
- DOI
  10.3892/ol.2021.13021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07139
[Journal Article] Expression of classical HLA class I antigens, HLA-E, and HLA-G is adversely prognostic in pancreatic cancer patients.2020
- Author(s)
  Hiraoka N, Ino Y, Hori S, Yamazaki-Itoh R, Naito C, Shimasaki M, Esaki M, Nara S, Kishi Y, Shimada K, Nakamura N, Torigoe T, Heike Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: in press Issue: 8 Pages: 3057-3070
- DOI
  10.1111/cas.14514
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07008
[Journal Article] Details of human epidermal growth factor receptor 2 status in 454 cases of biliary tract cancer.2020
- Author(s)
  Hiraoka N, Nitta H, Ohba A, Yoshida H, Morizane C, Okusaka T, Nara S, Esaki M, Kishi Y, Shimada K.
- Journal Title
  
  Hum Pathol
  
  Volume: 105 Issue: 1 Pages: 9-19
- DOI
  10.1080/2162402x.2020.1838812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07008
[Journal Article] Clinicopathological significance of core 3 O-glycan synthetic enzyme, β1,3-N-acetylglucosaminyltransferase 6 in pancreatic ductal adenocarcinoma.2020
- Author(s)
  Doi N, Ino Y, Angata K, Shimada K, Narimatsu H, Hiraoka N.
- Journal Title
  
  PLoS One
  
  Volume: 15 Issue: 11 Pages: e0242851-e0242851
- DOI
  10.1371/journal.pone.0242851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07008
[Journal Article] Reduction of intrapancreatic neural density in cancer tissue predicts poorer outcome in pancreatic ductal carcinoma.2019
- Author(s)
  Iwasaki T, Hiraoka N, Ino Y, Nakajima K, Kishi Y, Nara S, Esaki M, Shimada K, Katai H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110 Issue: 4 Pages: 1491-1502
- DOI
  10.1111/cas.13975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07008
[Journal Article] Reliable evaluation of tumor-infiltrating lymphocytes in pancreatic cancer tissue biopsies.2019
- Author(s)
  Ino Y, Oguro S, Yamazaki-Itoh R, Hori S, Shimada K, Hiraoka N
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 10 Pages: 1149-1159
- DOI
  10.18632/oncotarget.26646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07008
[Journal Article] Reduction of intrapancreatic neural density in cancer tissue predicts poorer outcome in pancreatic ductal carcinoma.2019
- Author(s)
  Iwasaki T, Hiraoka N, Ino Y, Nakajima K, Kishi Y, Nara S, Esaki M, Shimada K, Katai H.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Pages: 1491-1502
- Data Source
  KAKENHI-PROJECT-16K08663
[Journal Article] Reliable evaluation of tumor-infiltrating lymphocytes in pancreatic cancer tissue biopsies.2019
- Author(s)
  Ino Y, Oguro S, Yamazaki-Itoh R, Hori S, Shimada K, Hiraoka N.
- Journal Title
  
  Oncotarget
  
  Volume: 10 Pages: 1149-1159
- Data Source
  KAKENHI-PROJECT-16K08663
[Journal Article] Clinicopathologic Association and Prognostic Value of Microcystic, Elongated, and Fragmented (MELF) Pattern in Endometrial Endometrioid Carcinoma.2017
- Author(s)
  Kihara A, Yoshida H, Watanabe R, Takahashi K, Kato T, Ino Y, Kitagawa M, Hiraoka N.
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 41(7) Pages: 896-905
- Data Source
  KAKENHI-PROJECT-16K08663
[Journal Article] An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation-Negative Pancreatic Ductal Adenocarcinoma.2017
- Author(s)
  Shimada Y, Kohno T, Ueno H, Ino Y, Hayashi H, Nakaoku T, Sakamoto Y, Kondo S, Morizane C, Shimada K, Okusaka T, Hiraoka N.
- Journal Title
  
  Oncologist
  
  Volume: 22(2) Pages: 158-164
- Data Source
  KAKENHI-PROJECT-16K08663
[Journal Article] Strong antitumor efficacy of a pancreatic tumor-targeting oncolytic adenovirus for neuroendocrine tumors.2017
- Author(s)
  Yamamoto Y, Nagasato M, Rin Y, Henmi M, Ino Y, Yachida S, Ohki R, Hiraoka N, Tagawa M, Aoki K.
- Journal Title
  
  Cancer Med.
  
  Volume: 6(10) Pages: 2385-2397
- Data Source
  KAKENHI-PROJECT-16K08663
[Journal Article] Plasma membrane expression of ZNF185 is a prognostic factor in pancreatic ductal carcinoma2017
- Author(s)
  Furukawa Daisuke、Chijiwa Tsuyoshi、Matsuyama Masahiro、Mukai Masaya、Matsuo Ei-Ichi、Nishimura Osamu、Kawai Kenji、Suemizu Hiroshi、Nakagohri Toshio、Ozawa Soji、Shimada Kazuaki、Hiraoka Nobuyoshi、Nakamura Masato
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Issue: 3 Pages: 3633-3640
- DOI
  10.3892/ol.2017.6633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07096
[Journal Article] Tumor-associated CD204+ M2 macrophages are unfavorable prognostic indicators in uterine cervical adenocarcinoma.2017
- Author(s)
  Kawachi A, Yoshida H, Kitano S, Ino Y, Kato T, Hiraoka N.
- Journal Title
  
  Cancer Sci
  
  Volume: 109(3) Pages: 863-870
- Data Source
  KAKENHI-PROJECT-16K08663
[Journal Article] CIC-rearranged Sarcomas: A Study of 20 Cases and Comparisons With Ewing Sarcomas2016
- Author(s)
  Yoshida A, Goto K, Kodaira M, Kobayashi E, Kawamoto H, Mori T, Yoshimoto S, Endo O, Kodama N, Kushima R, Hiraoka N, Motoi T, Kawai A.
- Journal Title
  
  Am J Surg Pathol.
  
  Volume: 40 Issue: 3 Pages: 313-23
- DOI
  10.1097/pas.0000000000000570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460463, KAKENHI-PROJECT-15K19065, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-25460448
[Journal Article] A significant subgroup of resectable gallbladder cancer patients has an HER2 positive status.2016
- Author(s)
  Yoshida H, Shimada K, Kosuge T, Hiraoka N
- Journal Title
  
  Virchows Arch.
  
  Volume: Apr;468(4): Issue: 4 Pages: 431-9
- DOI
  10.1007/s00428-015-1898-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] Clinical significance of tumor-infiltrating immune cells focusing on BTLA and Cbl-b in patients with gallbladder cancer.2015
- Author(s)
  Oguro S, Ino Y, Shimada K, Hatanaka Y, Matsuno Y, Esaki M, Nara S, Kishi Y, Kosuge T, Hiraoka N.
- Journal Title
  
  Cancer Sci
  
  Volume: Dec;106(12) Issue: 12 Pages: 1750-60
- DOI
  10.1111/cas.12825
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-24590674, KAKENHI-PROJECT-25460486
[Journal Article] ACTN4 copy number increase as a predictive biomarker for chemoradiotherapy of locally advanced pancreatic cancer.2015
- Author(s)
  Watanabe T, Ueno H, Watabe Y, Hiraoka N, Morizane C, Itami J, Okusaka T, Miura N, Kakizaki T , Kakuya T, Kamita M, Tsuchida A, Nagakawa Y, Wilber H, Yamada T and Honda K
- Journal Title
  
  Br J Cancer
  
  Volume: Feb 17;112(4) Issue: 4 Pages: 704-13
- DOI
  10.1038/bjc.2014.623
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-25670868
[Journal Article] TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast.2015
- Author(s)
  Yoshida M, Ogawa R, Yoshida H, Maeshima A, Kanai Y, Kinoshita T, Hiraoka N, Sekine S.
- Journal Title
  
  Br J Cancer
  
  Volume: Oct 20;113(8) Issue: 8 Pages: 1244-8
- DOI
  10.1038/bjc.2015.326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] Intratumoral tertiary lymphoid organ is a favorable prognosticator in patients with pancreatic cancer.2015
- Author(s)
  Hiraoka N, Ino Y, Yamazaki-Itoh R, Kanai Y, Kosuge T, Shimada K.
- Journal Title
  
  Br J Cancer
  
  Volume: 112 Issue: 11 Pages: 1782-90
- DOI
  10.1038/bjc.2015.145
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460486
[Journal Article] Potential diagnostic biomarkers: differential expression of LMP2/β1i and cyclin B1 in human uterine leiomyosarcoma.2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Sudo T, Ishiko O, Yaegashi N, Aburatani H, Konishi I.
- Journal Title
  
  Tumori
  
  Volume: Jul-Aug;100(4):
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.2014
- Author(s)
  Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, Tycko B,Tsukada T, Kanai Y, Sumi S, Namiki H, Taya Y, Shibata T, Nakagama H.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: Jun 10;111(23) Issue: 23
- DOI
  10.1073/pnas.1319962111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-26430133, KAKENHI-PROJECT-26462053
[Journal Article] Twenty-six Cases of Advanced Ampullary Adenocarcinoma2014
- Author(s)
  Shoji H, Morizane C, Hiraoka N, Kondo S, Ueno H, Ohno I, Shimizu S, Mitsunaga
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] Histopathological characteristics of hypervascular cholangiocellular carcinoma as an early stage of cholangiocellular carcinoma.2014
- Author(s)
  Sato Y, Ojima H, Onaya H, Mori T, Hiraoka N, Kishi Y, Nara S, Esaki M, Shimada
- Journal Title
  
  Hepatol Res.
  
  Volume: Sept 6 Issue: 11 Pages: 1119-1129
- DOI
  10.1111/hepr.12236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518, KAKENHI-PROJECT-25670868
[Journal Article] Early venous return in hepatic angiomyolipoma due to an intratumoral structure resembling an arteriovenous fistula.2013
- Author(s)
  Iwao Y, Ojima H, Onaya H, Sakamoto Y, Kishi Y, Nara S, Esaki M, Mizuguchi Y, Ushigome M, Asahina D, Hiraoka N, Shimada K, Kosuge T, Kanai Y.
- Journal Title
  
  Hepatol Res.
  
  Volume: May 17 Issue: 6 Pages: 700-706
- DOI
  10.1111/hepr.12163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518
[Journal Article] Bile duct carcinoma involving the common channel associated with pancreaticobiliary maljunction shows an extension pattern similar to ductal carcinoma of the pancreas.2013
- Author(s)
  Yoshida N, Esaki M, Kishi Y, Shimada K, Ojima H, Kanai Y, Hiraoka N.
- Journal Title
  
  Pathol Int
  
  Volume: Aug;63(8): Issue: 8 Pages: 415-8
- DOI
  10.1111/pin.12085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518
[Journal Article] Pancreatic intraglandular metastasis predicts poorer outcome in postoperative patients with pancreatic ductal carcinoma.2013
- Author(s)
  Oguro S, Shimada K, Ino Y, Esaki M, Nara S, Kishi Y, Kosuge T, Kanai Y, Hiraoka N.
- Journal Title
  
  Am J Surg Pathol.
  
  Volume: Jul;37(7): Issue: 7 Pages: 1030-8
- DOI
  10.1097/pas.0b013e3182834d22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23791518
[Journal Article] Gemcitabine in patients with intraductal papillary mucinous neoplasm with an associated invasive carcinoma of the pancreas.2013
- Author(s)
  Otsuka T, Morizane C, Nara S, Ueno H, Kondo S, Shimada K, Kosuge T, Ikeda M, Hiraoka N, Okusaka T
- Journal Title
  
  Pancreas.
  
  Volume: Jul;42(5) Issue: 5 Pages: 889-892
- DOI
  10.1097/mpa.0b013e3182826f1f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer.2013
- Author(s)
  : Ino Y, Yamazaki-Itoh R, Shimada K, Iwasaki M, Kosuge T, Kanai Y, Hiraoka N.
- Journal Title
  
  Br J Cancer.
  
  Volume: Mar 5;108(4) Issue: 4 Pages: 914-23
- DOI
  10.1038/bjc.2013.32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms.2013
- Author(s)
  Nishikawa G, Sekine S, Ogawa R, Matsubara A, Mori T, Taniguchi H, Kushima R, Hiraoka N, Tsuta K, Tsuda H, Kanai Y.
- Journal Title
  
  Br J Cancer.
  
  Volume: Mar 5;108(4): Issue: 4 Pages: 951-8
- DOI
  10.1038/bjc.2013.47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-25670868
[Journal Article] High levels of FOXP3⁺ regulatory T cells in gastric MALT lymphoma predict responsiveness to Helicobacter pylori eradication.2013
- Author(s)
  Iwaya Y, Kobayashi M, Momose M, Hiraoka N, Sakai Y, Akamatsu T, Tanaka E, Ohtani H, Fukuda M, Nakayama J.
- Journal Title
  
  Helicobacter.
  
  Volume: Oct;18(5) Issue: 5 Pages: 356-62
- DOI
  10.1111/hel.12051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-24590410
[Journal Article] Yoshida T, Saeki N.Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis2012
- Author(s)
  Ono H, Hiraoka N, Lee YS, Woo SM, Lee WJ, Choi IJ, Saito A, Yanagihara K, Kanai Y, Ohnami S, Chiwaki F, Sasaki H, Sakamoto H, Yoshida T, Saeki N
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: 51(1) Pages: 30-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in the early intraepithelial stages of human pancreatic carcinogenesis.2011
- Author(s)
  Hiraoka N, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 140 Pages: 310-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590451
[Journal Article] CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in the early intraepithelial stages of human pancreatic carcinogenesis2011
- Author(s)
  Hiraoka N. Yamazaki-Itoh R. Ino Y., et al
- Journal Title
  
  Gastroenterology
  
  Volume: 140 Issue: 1 Pages: 310-321
- DOI
  10.1053/j.gastro.2010.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590451
[Journal Article] Intrapancreatic nerve invasion as a predictor for recurrence after pancreaticoduodenectomy in patients with invasive ductal carcinoma of the pancreas2011
- Author(s)
  Shimada K, Nara S, Esaki M, Sakamoto Y, Kosuge T, Hiraoka N
- Journal Title
  
  Pancreas.
  
  Volume: 40(3) Pages: 464-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] Macrophage-capping protein as a tissue biomarker for prediction of response to gemcitabine treatment and prognosis in cholangiocarcinoma2011
- Author(s)
  Morofuji N, Ojima H, Onaya H, Okusaka T, Shimada K, Sakamoto Y, Esaki M, Nara S, Kosuge T, Asahina D, Ushigome M, Hiraoka N, Nagino M, Kondo T
- Journal Title
  
  J Proteomics.
  
  Volume: 75(5) Pages: 1577-1589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469
[Journal Article] Tumor necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation2010
- Author(s)
  Hiraoka N. Ino Y. Sekine S., et al
- Journal Title
  
  Br J Cancer
  
  Volume: 103 Issue: 7 Pages: 1057-65
- DOI
  10.1038/sj.bjc.6605854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590451
[Journal Article] Tumor necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation.2010
- Author(s)
  Hiraoka N, et al.
- Journal Title
  
  Br.J.Cancer
  
  Volume: 103 Pages: 1057-1065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590451
[Journal Article] Tumor-infiltrating lymphocytes and hepatocellular carcinoma : Molecular biology2010
- Author(s)
  Hiraoka N
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 6 Issue: 6 Pages: 544-51
- DOI
  10.1007/s10147-010-0130-1
- NAID
  10027665099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590451
[Presentation] How to evaluate tumor-infiltrating immune cells in biopsied pancreatic cancer tissues2017
- Author(s)
  Yoshinori Ino, Rie Yamazaki-Itoh, Seiji Oguro, Shutaro Hori, Kazuaki Shimada,Nobuyoshi Hiraoka
- Organizer
  日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K08663
[Presentation] Zinc finger protein 185 is a key molecule of liver metastasis in colon cancer.2016
- Author(s)
  Furukawa D, Chijiwa T, Matsuyama M, Mukai M, Matsuo E, Nishimura O, Kawai K, Suemizu H, Nakagohri T, Yasuda S, Shimada K, Hiraoka N, Nakamura M.
- Organizer
  AACR Anual Meeting 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07096

1. ISHIKAWA Yoshinori (90291137)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. Kazufumi Honda (10260936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. MORI Taisuke (00296708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. Sekine Shigeki (10321879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. WATABE Yukio (50733490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. IZUMO Toshiyuki (80322709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Ohki Rieko (70356252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FURUKAWA Daisuke (70459478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. NAKAMURA Masato (00164335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. Kawashima Hiroto (50260336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIRAKAWA Jotaro (30609160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Yoshida Hiroshi (70750751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 下重美紀 (00392340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 八木原一博 (00538126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小嶋基寛 (30338470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 森実千種 (50501871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 山田正三 (80260131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 千々和剛 (70642180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 河村大輔 (10776082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 鈴木涼平 (30621809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 中嶋幸生 (80785775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 相島慎一 (70346774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 吉田裕樹 (40260715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 能城浩和 (90301340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 杉町圭史 (90452763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YAMAZAKI Rie

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. Yoshimoto Seiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRAOKA Nobuyoshi 平岡 伸介

平岡 伸介 ヒラオカ ノブヨシ

Research Projects

Research Products

Co-Researchers

Biological roles of neural system in pancreatic tumor immune microenvironmentPrincipal Investigator

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直接抗ウイルス剤によるウイルス排除後肝癌における免疫微小環境の病理学的研究

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Formation and maintenance of tertiary lymphoid organsPrincipal Investigator

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Functional analysis of PHLDA3, a repressor of Akt, to elucidate the mechanism of neuroendocrine tumor development

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The analyses of epithelial-mesenchymal transition associating with LIM protein family ZNF185 using in vivo liver metastasis mouse models of the human pancreas cancer.

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Role and function control of vascular endothelial cells in pancreatic cancer immune microenvironment

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Novel anti-carbohydrate antibodies reveal the role of glycans in tumor malignancy and their use as tumor biomarkers

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The role of innate lymphoid cells in tumor immunity of pancreatic cancer

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Molecular mechanisms to form antitumor immune microenvironmentPrincipal Investigator

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Development of novel molecular targets for oral cancer with kinome profile by antibody-based proteomics

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Biological function and characteristics of human regulatory T cells : A new molecular pathwayPrincipal Investigator

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多段階発癌過程における抗腫瘍免疫応答の変化とその機構の解明Principal Investigator

Principal Investigator

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ヒト生殖細胞の分化・腫瘍化に関連する3種の新たな抗原分子の単離・同定とその機能Principal Investigator

Principal Investigator

Project Period (FY)

HIRAOKA Nobuyoshi 平岡伸介

平岡伸介ヒラオカノブヨシ