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SAKAMOTO EIJI  阪本 英二

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SAKAMOTO Aiji  阪本 英二

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Researcher Number 40291067
Other IDs
Affiliation (Current) 2025: 大阪人間科学大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help 2015 – 2018: 国立研究開発法人国立循環器病研究センター, 研究所, 室長
2012 – 2014: 独立行政法人国立循環器病研究センター, 研究所, 室長
2011: 独立行政法人国立循環器病研究センター, 血管生理学部, 室長
2001: Research Institute of NCVC, Chief Investigator, 室長
2000 – 2001: 国立循環器病センター研究所, バイオサイエンス部, 室長 … More
1999: 国立循環器病センター, 研究所, 室長(研究職)
1998: 国立循環器病センター, 室長
1998: 国立循環器病センター研究所, 室長
1998: 国立循環器病センター研究所, バイオサイエンス部バイオテクノロジー特殊実験室, 室長
1997: Cellular Physiology Laboratory, RIKEN,The Special Postductoral Researcher of RIK, 理科学研究所, 基礎科学研究員
1997: 理化学研究所, 細胞生理学研究室, 基礎科学特別研究員 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / General medical chemistry / General pharmacology
Except Principal Investigator
Circulatory organs internal medicine / Public health/Health science
Keywords
Principal Investigator
心臓病 / 心不全 / ハムスター / 心筋症 / 薬理学 / 循環器 / ゲノム / 突然変異 / 探索研究 / 分子病態 … More / 分子機構 / 同期的収縮 / T管 / 心筋細胞 / 生体内防護機構 / 発症原因遺伝子 / 1心臓病 / 加齢 / アルビノ / 心筋症ハムスター / 視機能 / 遺伝性疾患 / チロシナーゼ / 網膜色素上皮 / 白子症 / 代償性心肥大 / ジストロフィン結合タンパク質複合体 / サルコグリカン / 心筋変性 / ジストロフィン結合タンパク質総合体 / サルユグリカン / 遺伝病 … More
Except Principal Investigator
MELAS / Gene / 心筋症 / ミトコンドリア / D-loop / DCM / HCM / Mitochondria / Sudden death / Diagnosis / 予防医学 / 発症前診断 / Dループ / 遺伝子 / Dルーフ / 拡張型心筋症 / 肥大型心筋症 / 突然死 / 遺伝子診断 / Echocardiography / CMV / Lac Z / δ-SG / rAAV / Therapy / サイコグリカン / リポソーム / 薬物療法 / 細胞骨格蛋白 / 予後 / AAVベクター / サルコグリカン / 遺伝子治療 / mitochondrial / NOS inhibitors / beta-galactosidase / apoptosis / cardiomyocytes / virus vector / gene transfered / nitric oxide synthase / ウィルスベクター / NOS阻害剤 / β-ガラクトシダーゼ / アポトーシス / 心筋 / ウイルスベクター / 遺伝子導入 / 一酸化窒素合成酵素 Less
  • Research Projects

    (8 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (9 People)
  •  Creation and application of a new hamster line lacking beta-B1 crystallinPrincipal Investigator

    • Principal Investigator
      Sakamoto Aiji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Genetic analysis of molecular networks supporting cardiac T-tubulesPrincipal Investigator

    • Principal Investigator
      Sakamoto Eiji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Study on βB1-crystallin and HeartPrincipal Investigator

    • Principal Investigator
      SAKAMOTO Aiji
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Cardiovascular Center Research Institute
  •  眼の色の視覚機能における動きの研究Principal Investigator

    • Principal Investigator
      阪本 英二
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Gene therapy of advanced heart failure

    • Principal Investigator
      TOYO-OKA Teruhiko
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tokyo
  •  Gene diagnoics of Sudden death and its practise

    • Principal Investigator
      TOYO-OKA Teruhiko
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Public health/Health science
    • Research Institution
      University of Tokyo
  •  心筋症ハムスターの分子生物学的解析Principal Investigator

    • Principal Investigator
      阪本 英二
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General medical chemistry
    • Research Institution
      National Cardiovascular Center Research Institute
      The Institute of Physical and Chemical Research
  •  Functional analysis of nitric oxide synthase related genes transfered into cardiomyocytes in viv

    • Principal Investigator
      SHIN Wea.Soo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo

All 2017 2015 2013 2012 2011 Other

All Presentation

  • [Presentation] Cardiomyopathic hamsters: delta-sarcoglycan and beyond2017

    • Author(s)
      Aiji Sakamoto & Kageyoshi Ono
    • Organizer
      PCS 4th World Congress of Cardiothoracic-Renal Diseases-2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15207
  • [Presentation] Spontaneous mutations occurring on the two closely interactive proteins, delta-sarcoglycan and desmin, lead to severe dilated cardiomyopathy in TO-2 hamster2015

    • Author(s)
      A. Sakamoto, K. Ono
    • Organizer
      BIT's 7th Annual International Congress of Cardiology
    • Place of Presentation
      Shanghai, People’s Republic of China
    • Year and Date
      2015-12-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25670171
  • [Presentation] TO-2 Hamster : Unique Animal Model for Severe Cardiomyopathy2013

    • Author(s)
      Aiji Sakamoto & Kageyoshi Ono
    • Organizer
      2^<nd> Biotechnology World Congress
    • Place of Presentation
      ドバイ(アラブ首長国連邦)
    • Year and Date
      2013-02-19
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] Hamster model for severe cardiomyopathy caused by double natural mutations2013

    • Author(s)
      Aiji Sakamoto, Kageyoshi Ono
    • Organizer
      MipTec-The: Leading European Event for Drug Discovery
    • Place of Presentation
      バーゼル、スイス
    • Data Source
      KAKENHI-PROJECT-25670171
  • [Presentation] Molecular Mechanisms Aggravating Hereditary Cardiomyopathy in TO-2 Hamster2013

    • Author(s)
      A. Sakamoto, Kageyoshi Ono
    • Organizer
      第36回心筋代謝研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25670171
  • [Presentation] BIO14.6心筋症ハムスターにおける水晶体変性とβB1クリスタリン遺伝子における点突然変異2013

    • Author(s)
      阪本英二、佐々木健、南野直人
    • Organizer
      第39回水晶体研究会
    • Place of Presentation
      東京
    • Year and Date
      2013-01-12
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] TO-2 Hamster: Unique Animal Model for Severe Cardiomyopathy2013

    • Author(s)
      Aiji Sakamoto, Kageyoshi Ono
    • Organizer
      2nd Biotechnology World Congress
    • Place of Presentation
      ドバイ(アラブ首長国連邦)
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] Desmin A191T Point Mutation Aggravates delta-Sarcoglycan-Deficient Cardiomyopathy in TO-2 Hamster2012

    • Author(s)
      阪本英二
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-18
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] Desmin A191T Point Mutation Aggravates delta-Sarcoglycan-Deflcient Cardiomyopathy in TO-2 Hamster2012

    • Author(s)
      阪本英二
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] CARDIOMYOPATHIC HAMSTERS: DELTA-SARCOGLYCAN AND BEYOND2012

    • Author(s)
      Aiji Sakamoto
    • Organizer
      35th Annual Meeting of the Japanese Working Group "Cardiac Structure and Metabolism"
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] Desmin A191T Mutation Aggravates delta-Sarcoglycan-Deflcient Cardiomyopathy in TO-2 Hamster2011

    • Author(s)
      Aiji Sakamoto & Kageyoshi Ono
    • Organizer
      American Heart Association Scientific Sessions 2011
    • Place of Presentation
      米国フロリダ州オーランド
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] Desmin A191T Mutation Aggravates delta-Sarcoglycan-Deficient Cardiomyopathy in TO-2 Hamster2011

    • Author(s)
      Aiji Sakamoto & Kageyoshi Ono
    • Organizer
      American Heart Association Scientific Sessions 2011
    • Place of Presentation
      オーランド(米国)
    • Year and Date
      2011-11-14
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] CARDIOMYOPATHIC HAMSTERS : DELTA-SARCOGLYCAN AND BEYOND

    • Author(s)
      Aiji Sakamoto
    • Organizer
      35th Annual Meeting of the Japanese Working Group "Cardiac Structure and Metabolism"
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23659179
  • [Presentation] TO-2 hamster: Unique rodent model for severe cardiomyopathy caused by double spontaneous mutations

    • Author(s)
      A. Sakamoto, K. Ono
    • Organizer
      17th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2014-07-13 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-25670171
  • 1.  SHIN Wea.Soo (10211971)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  TOYOOKA Teruhiko (00146151)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  ONO Kageyoshi (40177259)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 4.  SUZUKI Jun-ichi (50260485)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  UEHARA Yoshio (40184965)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KAWADA Tomie (00186107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TOMARU Takanobu (60180163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NAKAMURA Fumitaka (20261969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  石川 隆俊 (30085633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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