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SHIBAKI Akihiko  芝木 晃彦

ORCIDConnect your ORCID iD *help
… Alternative Names

芝木 晃彦  シバキ アキヒコ

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Researcher Number 40291231
External Links
Affiliation (based on the past Project Information) *help 2013: 北海道大学, 医学(系)研究科(研究院), 客員研究員
2011 – 2012: 北海道大学, 医学(系)研究科(研究院), 非常勤講師
2011: 北海道大学, 北海道大学病院, 講師
2010: Hokkaido University, 大学院・医学研究科, 非常勤講師
2009: Hokkaido University, 大学病院, 講師 … More
2009: 北海道大学, 大学院・医学研究科, 助教
2008: 北海道大学, 大学院・医学研究科, 講師
2008: Hokkaido University, 病院, 講師
2005 – 2008: 北海道大学, 北海道大学病院, 講師
2007: 北海道大学, 大学病院, 講師
2006: 北海道大学, 病院・講師
2005: Hokkaido Univ., Hokkaido University Hospital, Lec., 病院, 講師
2005: 北海道大学病院, 講師
2002 – 2004: 北海道大学, 大学院・医学研究科, 助手
1998: 北海道大学, 医学部・附属病院, 助手
1997: 北海道大学, 医学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Dermatology
Except Principal Investigator
Dermatology / Biological Sciences
Keywords
Principal Investigator
GVHD / 自己免疫性疾患 / T細胞 / 細胞・組織 / 臨床 / 治療 / 免疫 / 皮膚病理学 / リンパ球 / トレランス … More / トランスジェニックマウス / モデルマウス / Tissue / Cell / Clinic / Treatment / Immunology / Skin pathology / tolerance / transgenic mouse / model mouse / T cell / autoimmune disease / 補体活性化 / 抗体サブクラス / IgG1/IgG4 / 疾患モデル動物 / ヒト化マウス / 17型コラーゲン / 水疱性類天疱瘡 / 自己免疫疾患 / 動物モデル / 国際情報交換 / CO-Stimulatory molecule / IgEレセプター / IgE / ランゲルハンス細胞 / ビタミンD3 / レチノイド / サイトカイン / 単球 / アトピー性皮膚炎 … More
Except Principal Investigator
細胞・組織 / 臨床 / 遺伝子 / 癌 / 動物 / 免疫学 / 免疫 / pathology / internal medicine / tIssue / cell / animal / immunology / 病理学 / 内科 / 自己免疫性疾患 / NOD-Scid / CHO細胞 / 疾患モデル動物 / ヒト化マウス / 17型コラーゲン / 水疱性類天疱瘡 / 自己免疫疾患 / 再生治療 / 遺伝子治療 / 再生医療 / 皮膚炎症 / バイオテクノロジー / 生体機能利用 / 応用動物 / 治療 / 皮膚病理学 / 体細胞超変異 / 早期診断 / B細胞リンパ腫 / 免疫療法 / 悪性黒色腫 / ワクチン / 角層剥離皮膚 / ランゲルハンス細胞 / ペプチド / 細胞障害性T細胞 / 臨床試験 / 経皮免疫療法 / 悪性黒色種 / マイクロアレイ / VII型コラーゲン / 接着分子 / 転移 Less
  • Research Projects

    (17 results)
  • Research Products

    (69 results)
  • Co-Researchers

    (25 People)
  •  Development of novel treatment targeting complement for bullous pemphigoidPrincipal Investigator

    • Principal Investigator
      SHIBAKI Akihiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Analysis of pathomechanisms of bullous pemphigoid and development of novel therapy by using humanized active mouse model

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Generation of a disease model for epidermolysis bullosa acquisita using autoantigen-humanized mice and application for the development of novel treatmentPrincipal Investigator

    • Principal Investigator
      SHIBAKI Akihiko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Gene therapy for refractory skin ulcer by using Histone deacetylase inhibitor

    • Principal Investigator
      YASUKAWA Kana
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  17型コラーゲンectodomain sheddingの生理的機能の解明

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤、転移能における表皮接着分子の直接的関与についての解析

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Immunotherapy with percutaneous peptide immunization in human melanoma

    • Principal Investigator
      TAKIGAWA Masahiro
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Hamamatsu University School of Medicine
  •  The investigation to establish an early dianosis for cutaneous B cell lymphoma through the analysis for somatic hypermutation associated factors

    • Principal Investigator
      KODAMA Kazuo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  水疱性類天疱瘡病的抗原に対するヒト型モノクローナル抗体の作成と治療への応用

    • Principal Investigator
      王 剛
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Study of the pathologic mechanisms in Epidermolysis bullosa acquisita model micePrincipal Investigator

    • Principal Investigator
      SHIBAKI Akihiko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤、転移能における表皮接着分子の直接的関与についての解析

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Study of the pathologic mechanisms and development of the novel therapeutic strategy using bullous pemphigoid model mice

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤、転移能における表皮接着分子の直接的関与についての解析

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Study of the pathologic mechanisms in the autoimmune skin disease using double transgenic micePrincipal Investigator

    • Principal Investigator
      SHIBAKI Akihiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤,転移能における表皮接着分子の直接的関与についての解析

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  自己免疫性皮膚疾患発症におけるCD4陽性、CD8陽性T細胞サブセットの役割の解析Principal Investigator

    • Principal Investigator
      芝木 晃彦
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  アトピー性皮膚炎患者ランゲルハンス細胞によるTh2T細胞活性化についての研究Principal Investigator

    • Principal Investigator
      芝木 晃彦
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 第2版 皮膚疾患診療 実践ガイド 皮膚科遺伝相談2009

    • Author(s)
      守内玲寧, 芝木晃彦, 清水宏
    • Total Pages
      2
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 第2版 皮膚疾患診療 実践ガイド 水疱を生じる疾患2009

    • Author(s)
      守内玲寧, 芝木晃彦, 清水宏
    • Total Pages
      1
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 第2版 皮膚疾患診療 実践ガイド 膿疱を生じる疾患2009

    • Author(s)
      守内玲寧, 芝木晃彦, 清水宏
    • Total Pages
      1
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Noncollagenous 16A domain of type XVII collagen-reactive CD4+ T cells play a pivotal role in the development of active disease in experimental bullous pemphigoid model2012

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, ShinkumaS, Moriuchi R, Qiao H, Shimizu H
    • Journal Title

      Clin Immunol

      Volume: 142 Pages: 167-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Noncollagenous 16A domain of type XVII collagen-reactive CD4(+) T cells play a pivotal role in the development of active disease in experimental bullous pemphigoid model2012

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Shinkuma S, Moriuchi R, Qiao H, Shimizu H
    • Journal Title

      Clin Immunol

      Volume: 142 Issue: 2 Pages: 167-175

    • DOI

      10.1016/j.clim.2011.10.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20689021, KAKENHI-PROJECT-21249063, KAKENHI-PROJECT-23591635, KAKENHI-PROJECT-23659538, KAKENHI-PROJECT-23791242
  • [Journal Article] Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model2011

    • Author(s)
      Li Q, Ujiie H, Shibaki A, Wang G, Moriuchi R, Qiao HJ, Morioka H, ShinkumaS, Natsuga K, Long HA, Nishie W, ShimizuH
    • Journal Title

      J Immunol

      Volume: 185 Pages: 7746-7755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model.2010

    • Author(s)
      Li, Q, Shibaki A, et al.
    • Journal Title

      J Immunol

      Volume: 185 Pages: 17746-7755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Human IgG1 mAb against hCOL17 NC16A induces blisters via complement activation in experimental bullous pemphigoid model.2010

    • Author(s)
      Li Q, Shibaki A, Ujiie H, et al.
    • Journal Title

      Journal of Immunology

      Volume: 185 Pages: 7746-7755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1 alpha in autosomal recessive hypotrichosis.2010

    • Author(s)
      Shinkuma S, Shibaki A, et al.
    • Journal Title

      Human mutation

      Volume: 31(5) Pages: 602-610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591333
  • [Journal Article] Blockade of autoantibody-initiated tissue damage by using recombinant fab antibody fragments against pathogenic autoantigen2010

    • Author(s)
      Wang G, Ujiie H, Shibaki A, Nishie W, Tateishi Y, Kikuchi K, Li Q, McMillan JR, Morioka H, Sawamura D, Nakamura H, Shimizu H
    • Journal Title

      Am J Pathol 176

      Pages: 914-925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen.2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, et al.
    • Journal Title

      Journal of Immunology

      Volume: 184 Pages: 2166-2174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model.2010

    • Author(s)
      Li Q, Ujiie H, Shibaki A, Wang G, Moriuchi R, Qiao HJ, Morioka H, Shinkuma S, Natsuga K, Long HA, Nishie W, Shimizu H.
    • Journal Title

      Journal of Immunology 185(12)

      Pages: 7746-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591333
  • [Journal Article] Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1 alpha in autosomal recessive hypotrichosis.2010

    • Author(s)
      Shinkuma S, Akiyama M, Inoue A, Aoki J, Natsuga K, Nomura T, Arita K, Abe R, Ito K, Nakamura H, Ujiie H, Shibaki A, Suga H, Tsunemi Y, Nishie W, Shimizu H.
    • Journal Title

      Human mutation 31(5)

      Pages: 602-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591333
  • [Journal Article] Human IgGl monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model.2010

    • Author(s)
      Li Q, Ujiie H, Shibaki A, et al.
    • Journal Title

      Journal of Immunology

      Volume: 185(12) Pages: 7746-7755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591333
  • [Journal Article] What's new in bullous pemphigoid.2010

    • Author(s)
      Ujiie H, Shibaki A, et al.
    • Journal Title

      J Dermatol

      Volume: 37 Pages: 194-204

    • NAID

      10027065912

    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Successful treatment of nail lichen planus with topical tacrolimus2010

    • Author(s)
      Ujiie H, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      Acta Derm Venereol 90

      Pages: 218-219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Blockade of autoantibody-initiated tissue damage by using recombinant fab antibody tragments against pathogenic autoantigen.2010

    • Author(s)
      Wang G, Ujiie H, Shibaki A, Nishie W, Tateishi Y, Kikuchi K, Li Q, McMillan JR, Morioka H, Sawamura D, Nakamura H, Shimizu H.
    • Journal Title

      Human mutation 31(5)

      Pages: 602-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591333
  • [Journal Article] What's new in bullous pemphigoid.2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Shimizu H.
    • Journal Title

      Journal of Dermatology 37

      Pages: 194-204

    • NAID

      10027065912

    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] A novel active mouse model for bullous pmephigoid targeting humanized pathogenic antigen.2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, Akiyama M, Shimizu H.
    • Journal Title

      Journal of Immunology 184

      Pages: 2166-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Blockade of autoantibody-initiated tissue damage by using recombinant fabantibody traoments against pathogenic autoantiqen.2010

    • Author(s)
      Wang G, Shibaki A, et al.
    • Journal Title

      Human mutation

      Volume: 31(5) Pages: 602-640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591333
  • [Journal Article] Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model.2010

    • Author(s)
      Li Q, Ujiie H, Shibaki A, Wang G, Moriuchi R, Qiao HJ, Morioka H, Shinkuma S, natsuga K, Long HA, Nishie W, Shimizu H.
    • Journal Title

      Journal of Immunology 185

      Pages: 7746-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Blockade of autoantibody-initiated tissue damage by using recombinant Fab antibody fragments against pathogenic autoantigen.2010

    • Author(s)
      Wang G, Ujiie H, Shibaki A, Nishie W, Tateishi Y, Kikuchi K, Li Q, McMillan JR, Morioka H, Sawamura D, Nakamura H, Shimizu H.
    • Journal Title

      American Journal of Pathology 176

      Pages: 914-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, Akiyama M, Shimizu H
    • Journal Title

      J Immunol 184

      Pages: 2166-2174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A novel active mouse model for Bullous pemphigoid targeting humanized pathogenic antigen2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, AkiyamaM, Shimizu H
    • Journal Title

      J Immunol

      Volume: 184 Pages: 2166-6174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Scleroedema adultorum associated with sarcoidosis2009

    • Author(s)
      Inokuma D, Sawamura D, Shibaki A, Abe R, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Keratinocyte-/fibroblast-targeted rescue of Col7a1-disrupted mice and generation of an exact dystrophic epidermolysis bullosa model using human COL7A1 mutation.2009

    • Author(s)
      Ito K, Sawamura D, Goto M, Nakamura H, Nishie W, Sakai K, Natsuga K, Shinkuma S, Shibaki A, Uitto J, Denton CP, Nakajima O, Akiyama M, Shimizu H.
    • Journal Title

      American Journal of Pathology 175

      Pages: 2508-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Disseminated cutaneous Mycobacterium kansasii infection in an patient infected with the human immunodeficiency virus2009

    • Author(s)
      Nomura Y, Nishie W, Shibaki A, Ibata M, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

      Pages: 625-626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Collagen XVII participates in keratinocyte adhesion to collagen IV, and in p38MAPK-dependent migration and cell signaling2009

    • Author(s)
      Qiao H, Shibaki A, Long HA, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H, McMillan JR
    • Journal Title

      J Invest Dermatol 129

      Pages: 2288-2295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A novel humanized neonatal autoimmune blistering skin disease model induced by maternally transferred antibodies2009

    • Author(s)
      Nishie W, Sawamura D, Natsuga K, Shinkuma S, Goto M, Shibaki A, Ujiie H, Olasz E, Yancey KB, Shimizu H
    • Journal Title

      J Immunol 183

      Pages: 4088-4093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Conradi-Hunermann-Happle syndrome with abnormal lamellar granule contents2009

    • Author(s)
      Akiyama M, Sakai K, Hayasaka K, Tabata N, Yamada M, Ujiie H, Shibaki A, Shimizu H
    • Journal Title

      Br J Dermatol 160

      Pages: 1335-1337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Collagen XVII participates in keratinocyte adhesion to collagen IV, and in p38-MAPK-dependetn migration and cell signaling.2009

    • Author(s)
      Qiao H, Shibaki A, Long HA, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H, McMillan JR.
    • Journal Title

      Journal of Investigative Dermatology 129

      Pages: 2288-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Disseminated cutaneous Mycobacterium kansasii infection in a patient infected with the human immunoceficiency virus.2009

    • Author(s)
      Nomura Y, Nishie W, Shibaki A, Ibata M, Shimizu H.
    • Journal Title

      Clinical and Experimental Dermatology 34

      Pages: 625-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Keratinocyte-/fibroblast-targeted rescue of Co17a1-disrupted mice and generation of an exact dystrophic epidermolysis bullosa model using a-human COL7A1 mutation2009

    • Author(s)
      Ito K, Sawamura D, Goto M, Nakamura H, Nishie W, Sakai K, Natsuga K, Shinkuma S, Shibaki A, Uitto J, Denton CP, Nakajima O, Akiyama M, Shimizu H
    • Journal Title

      Am J Pathol 175

      Pages: 2508-2517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Cutaneous pemphigus vulgaris with skin features similar to the classic mucocutaneous type : a case report and review of the literature.2008

    • Author(s)
      Shinkuma S, Nishie W, Shibaki A, Sawamura D, Ito K, Tsuji-Abe Y, Natsuga K, Chan PT, Amagai m, Shimizu H.
    • Journal Title

      Clinical and Experimental Dermatology 33

      Pages: 724-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Journal Article] Fibroblasts Show More Potential as Target Cells than Keratinocytes in COL7A1Gene Therapy of Dystrophic Epidermolysis Bullosa.2006

    • Author(s)
      Goto M, Sawamura D, Ito K, Abe M, Nishie W, Sakai K, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol in press

    • Data Source
      KAKENHI-PROJECT-17014004
  • [Journal Article] Fibroblasts show more potentials as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa.2006

    • Author(s)
      Goto M, Sawamura D, Ito K, Abe M, Nishie W, Sakai K, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol in press

    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Epidermodysplasia verruciformis and Generalized verrucosis : the same disease? Report of a case2006

    • Author(s)
      Yanagi T, Shibaki A, Tsuji-Abe Y, Yokota K, Shimizu H
    • Journal Title

      Clinc Exp Dermatol 54

      Pages: 362-363

    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Beta defensin-3 engineered epidermis shows highly protective effect for bacterial infection.2005

    • Author(s)
      Sawamura D, Goto M, Shibaki A, et al.
    • Journal Title

      Gene Ther 12

      Pages: 857-861

    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Novel ALDH3A2 heterozygous mutations are associated with defective lamellar ganule formation in a Japanese family of Sjogren-Larsson syndrome.2004

    • Author(s)
      Shibaki A, et al.
    • Journal Title

      J Invest Dermatol 123

      Pages: 1197-1199

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Induction of GVHD-like skin disease by passively transferred CD8+ T-cell receptor transgenic mice.2004

    • Author(s)
      Shibaki A, et al.
    • Journal Title

      J Invest Dermatol 123

      Pages: 109-115

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Induction of GVHD-like skin disease by passively transferred CD8+ T cell receptor transgenic T cells into keratin 14-ovalubumin transgenic mice.2004

    • Author(s)
      Shibaki A., et al.
    • Journal Title

      J Invest Dermatol 123・1

      Pages: 109-115

    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] 北海道における皮膚限局型スポロトリコーシスの1例.2004

    • Author(s)
      芝木 晃彦, 他
    • Journal Title

      皮膚科の臨床 46

      Pages: 799-803

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Cutaneous localized sporotrichosis in Hokkaido, a northern Japanese prefecture.2004

    • Author(s)
      Shibaki A, et al.
    • Journal Title

      Rinso Derma 46

      Pages: 799-803

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Novel ALDH3A2 heterozygous mutations are associated with defective lamellar granule formation in a Japanese family of Sjogren-Larsson syndrome.2004

    • Author(s)
      Shibaki A, et al.
    • Journal Title

      J Invest Dermatol 123

      Pages: 1197-1199

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591085
  • [Journal Article] Fibroblasts Show More Potential as Target Cells than Keratinocytes in COL7A1Gene Therapy of Dystrophic Epidermolysis Bullosa.

    • Author(s)
      Goto M, Sawamura D, Ito K, Abe M, Nishie W, Sakai K, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol (in press)

    • Data Source
      KAKENHI-PROJECT-17209038
  • [Journal Article] Two cases of cutaneous sporotrichosis in continental/microthermal climatezone : global warming alert?

    • Author(s)
      Inokuma D, Shibaki A, Shimizu H
    • Journal Title

      Clin Exp Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Patent] ポリペプチドを有効成分とする自己免疫性皮膚疾患治療薬2007

    • Inventor(s)
      清水 宏, 芝木晃彦, 王剛
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2007-073696
    • Filing Date
      2007-03-20
    • Data Source
      KAKENHI-PROJECT-18591230
  • [Presentation] Bullous pemphigoid autoantibodies induce skin fragility in neonatal mice in a complement-independent manner2013

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Nakamura H, Shimizu H
    • Organizer
      The 6th International Investigative Dermatology 2013
    • Place of Presentation
      イギリス
    • Year and Date
      2013-05-09
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Bullous pemphigoid autoantibodies induce skin fragility in neonatal mice in a complement-independent manner.2013

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Nakamura H, Shimizu H
    • Organizer
      The 6th International Investigative Dermatology 2013
    • Place of Presentation
      Edinburgh International Conference Centre (イギリス)
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Monoclonal human IgG1 and IgG4 against COL17 induce skin fragility in neonatal COL17-humanized mice in a complement-independent manner.2012

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Shinkuma S, Tanabe M, Nakamura H, Shimizu H
    • Organizer
      The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      ロワジールホテル&スパタワー那覇(沖縄県)
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Monoclonal human IgG1 and IgG4 against COL17 induce skin fragility in neonatal COL17-humanized mice in a complement-independent manner2012

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Shinkuma S, Tanabe M, Nakamura H, Shimizu H
    • Organizer
      The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      沖縄県
    • Year and Date
      2012-12-07
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Therapeutic Strategies For TargetingAutoreactive T Cells In Autoimmune Bullous Diseases2011

    • Author(s)
      Ujiie H, Shibaki A, Moriuchi R, Shimizu H
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      Soul, Korea
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Novel Mouse Models of Human Skin Diseases2011

    • Author(s)
      Ujiie H, Nishie W, Fujita Y, ShibakiA, Shimizu H
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      Soul, Korea
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Human IgG1 mAb against human COL17 NC16A developed from BP patients induces blisters in experimental bullous pemphigoid model.2010

    • Author(s)
      Shibaki A.
    • Organizer
      Society for Investigative Dermatology Annual Meeting
    • Place of Presentation
      Hilton Atlanta, Atlanta, Georgia. (USA)
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Presentation] Human IgG1 mAb against human COL17 NC16A developed from BP patients induces blisters in experimental bullous pemphigoid model2010

    • Author(s)
      Shibaki A
    • Organizer
      Society for Investigative Dermatology Annual Meeting
    • Place of Presentation
      Hilton Atlanta, Atlanta, Georgia.(USA)
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Presentation] Hemidesmosomal collagen XVII enhances keratinocyte adhesion to collagen IV, and in p38-MAPK-dependent migration and cell signaling2009

    • Author(s)
      McMillan J, Qiao H, Shibaki A, Long H, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H
    • Organizer
      6th Annual Scientific Meeting Australasian Society for Dermatology Research
    • Place of Presentation
      Courtyard by Marriott Surfers Paradise, QLD, Australia
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 筋肉内浸潤および脾梗塞を呈した進行期菌状息肉症の1例2009

    • Author(s)
      渡邉美佳, 氏家英之, 馬場慶子, 阿部理一郎, 芝木晃彦, 山田洋介, 山口圭介, 神山俊哉, 清水宏
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 北海道で発症したスポロトリコーシス2009

    • Author(s)
      猪熊大輔, 芝木晃彦, 清水宏, 芝木秀臣
    • Organizer
      第378回日本皮膚科学会北海道地方会
    • Place of Presentation
      旭川市大雪クリスタルホール旭川
    • Year and Date
      2009-06-14
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 北海道で発症したスポロトリコーシス2009

    • Author(s)
      猪熊大輔, 芝木晃彦, 清水宏, 芝木秀臣
    • Organizer
      第61回日本皮膚科学会西部支部学術大会
    • Place of Presentation
      別府国際コンベンションセンター大分
    • Year and Date
      2009-10-25
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Development of an active bullous pemphigoid mouse model2009

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Nakamura H, Akiyama M, Shimizu H
    • Organizer
      The 4th Joint Meeting of Japanese Dermatological Association and Australasian College of Dermatologists
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Wells症候群との鑑別を要したアレルギー性肉芽種性血管炎(AGA)の1例2009

    • Author(s)
      松村若菜, 藤田靖幸, 馬場慶子, 山根尚子, 芝木晃彦, 清水宏, 片岡浩
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] タクロリム軟膏外用が奏効した爪扁平苔癬5例のまとめ2009

    • Author(s)
      氏家英之, 芝木晃彦, 秋山真志, 清水宏
    • Organizer
      第73回日本皮膚科学会東部支部学術大会
    • Place of Presentation
      甲府富土屋ホテル山梨
    • Year and Date
      2009-09-27
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 11歳男児にみられた乳腺嚢胞の1例2009

    • Author(s)
      林韻欣, 青柳哲, 齋藤奈央, 秦洋郎, 芝木晃彦, 清水宏
    • Organizer
      第379回日本皮膚科学会北海道地方会
    • Place of Presentation
      大正富山医薬品(株)5階会議室札幌
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Pathomechanism in bullous pemphigoid- evidence from the model anima-2009

    • Author(s)
      Shibaki A
    • Organizer
      The 4^<th> Joint Meeting of Japanese Dermatological Association and Australasian College of Dermatologists
    • Place of Presentation
      北海道大学学術交流会館
    • Year and Date
      2009-07-10
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Presentation] Pathomechanism in bullous pemphigoid- evidence from the model animal-.2009

    • Author(s)
      Shibaki A.
    • Organizer
      The 4^<th> Joint Meeting of Japanese Dermatological Association and Australasian College of Dermatologists
    • Place of Presentation
      札幌市
    • Year and Date
      2009-07-10
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Presentation] Collagen XVII participates in keratinocyte adhesion to collagen IV, and in p38-MAPK-dependent migration and cell signaling2009

    • Author(s)
      Qiao H, Shibaki A, Long H, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H, McMillan J
    • Organizer
      the 69th Society for Investigative Dermatology Annual Meeting
    • Place of Presentation
      Palais des congres Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Collagen XVII in hemidesmosomes is involved in keratinocyte-collagen IV adhesion and p38-MAPK-dependent cell migration and signaling2009

    • Author(s)
      McMillan J, Qiao H, Shibaki A, Long H, Wang G, Nishie W, Akiyama M, Shimizu H
    • Organizer
      The 39th European Society for Dermatological Research(ESDR)Annual Meeting
    • Place of Presentation
      Semmelweis University, Budapest, Hungary
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Development of an active disease model for bullous pemphigoid.2008

    • Author(s)
      Ujiie H, Shibaki A, et al.
    • Organizer
      International Investigative Dermatology 2008
    • Place of Presentation
      京都市
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-20591312
  • [Presentation] 全身性形質細胞増多症の一例2008

    • Author(s)
      斉藤奈央、芝木晃彦
    • Organizer
      第107回日本皮膚科学会学術大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2008-04-20
    • Data Source
      KAKENHI-PROJECT-18591228
  • 1.  AKIYAMA Masashi (60222551)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 16 results
  • 2.  SHIMIZU Hiroshi (00146672)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 34 results
  • 3.  ABE Riichiro (60344511)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 4.  HASHIZUME Hideo (50237921)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YAGI Hiroaki (20242779)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ITO Taisuke (90293638)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SEO Naohiro (50283354)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SAWAMURA Daisuke (60196334)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NISHIE Wataru (20443955)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 10.  ITO Kei (20421977)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  SHIMIZU Tadamichi (70260396)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 12.  TAKIGAWA Masahiro (80115873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TOKURA Yoshiki (00172156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SHIMAUCHI Takatoshi (90399204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SHIMADA Shinji (10114505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SHIBAGAKI Naotaka (40262662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KODAMA Kazuo (20322810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YASUKAWA Kana (10419202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ABE Yukiko (40374433)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  NISHIMURA Emi (70396331)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  UJIIE Hideyuki (60374435)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 22.  MCMILLAN James (30374721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  堀部 尚弘 (10306277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  王 剛 (30419957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  沢村 大輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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