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FUJINO Takahiro  藤野 貴広

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Fujino Takahiro  藤野 貴広

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Researcher Number 40292312
Other IDs
Affiliation (Current) 2025: 愛媛大学, 学術支援センター, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 愛媛大学, 学術支援センター, 准教授
2015: 愛媛大学, 学術支援センター, 准教授
2010 – 2012: 愛媛大学, 総合科学研究支援センター, 准教授
2007: Ehime University, Integrated Center for Sciences, Associate Professor
2004 – 2006: Ehime University, Integrated Center for Sciences, Associate Professor, 総合科学研究支援センター, 助教授
1998 – 2003: 東北大学, 遺伝子実験施設, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / Food science / Basic Section 59040:Nutrition science and health science-related / 食品科学・栄養科学
Except Principal Investigator
Experimental pathology
Keywords
Principal Investigator
アポE / アルツハイマー / ノックアウトマウス / リポタンパク受容体 / リポタンパクレセプター / リポタンパク / コレステロール / 中枢神経系 / エネルギー代謝 / アラキドン酸 … More / 脂肪酸活性化酵素 / 遺伝子発現調節 / 生活習慣病 / 酢酸代謝 / アポリポタンパクE / アポE / HDL / NPCI / Central Nervus System / Lipoprotein receptor / Sialic Acid / Glvcosvlation / ApoE / 脳神経系 / リソソーム病 / アポリポプロテインE / 中枢神経 / NPC1 / シアル酸 / 糖鎖修飾 / transcriptional regulation / transgenic mouse / glucose / skeletal muscle / lipid metabolism / starvation / グルコース飢餓 / ストレス応答 / 転写調節 / トランスジェニックマウス / グルコース / 骨格筋 / 脂質代謝 / 飢餓 / ケトン体 / 脂肪酸代謝 / 酢酸 / 寿命 / タンパク質修飾 / アセチル化 / 短鎖脂肪酸 / NAD依存性脱アセチル化酵素 / アセチルCoAシンテターゼ / タンパク質アセチル化 / アデノウィルス / リーリン / プロスタグラジン / プロスタグランジン / アポEレセプター / 遺伝子欠損マウス / エイコタペンタエン酸 / アシルコエンザイムA … More
Except Principal Investigator
炎症 / 膠原病疾患モデルマウス / 膠原病モデルマウス / 病理学 / 蛋白アナログ / 組換え近交系 / 膠原病脂環モデルマウス / 膠原病治療モデル / 競合的阻害 / 立体構造 / オステオポンチン Less
  • Research Projects

    (15 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (7 People)
  •  酢酸代謝によるエピジェネティックな遺伝子発現調節と生活習慣病との関連の解析Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Ehime University
  •  Analysis of metabolic pathways of apoE-containing lipoproteins in the brain for elucidation of sporadic Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      Fujino Takahiro
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Ehime University
  •  Development of therapeutic strategy by using recombinant-inbred model mouse strains of collagen disease

    • Principal Investigator
      Miyazaki Tatsuhiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Gifu University
  •  Significance of acetate metabolism in maintaining energy homeostasis during fastingPrincipal Investigator

    • Principal Investigator
      FUJINO Takahiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Ehime University
  •  Development of a glomerulonephritis therapeutic modelwith novel protein analogs targeting the polymorphic binding site of osteopontin (Opn)

    • Principal Investigator
      MIYAZAKI Tatsuhiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Ehime University
  •  エネルギー代謝によるタンパク質アセチル化の調節とその栄養学的意義Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Food science
    • Research Institution
      Ehime University
  •  Roles of lipoprotein receptor mediated signal transduction in metabolic syndromePrincipal Investigator

    • Principal Investigator
      FUJINO Takahiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      Ehime University
  •  脳におけるリポタンパク受容体の機能解析Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Ehime University
  •  脳におけるリポタンパク受容体の機能解析Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Regulation and expression of lipid-metabolizing enzymes in musclePrincipal Investigator

    • Principal Investigator
      FUJINO Takahiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Ehime University
      Tohoku University
  •  脳におけるリポタンパク受容体の機能解析Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  脳のリポタンパクレセプター機能と異常Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  アラキドン酸活性化酵素ノックアウトマウスの作製と解析Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      Tohoku University
  •  脳のリポタンパクレセプター機能と異常Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  アラキドン酸に特異的な脂肪酸活性化酵素に関する分子生物学的研究Principal Investigator

    • Principal Investigator
      藤野 貴広
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      Tohoku University

All 2013 2012 2011 2010 2008 2006 2005

All Journal Article Presentation

  • [Journal Article] Quantitative Analysis of the Interaction of Constitutive Androstane Receptor with Chemicals and Steroid Receptor Coactivator 1 Using Surface Plasmon Resonance Biosensor Systems: A Case Study of the Baikal Seal (Pusa sibirica) and the Mouse.2013

    • Author(s)
      Dau P. T., Sakai H., Hirano M., Ishibashi H., Tanaka Y., Kameda K, Fujino T., Kim EY. andIwata H.
    • Journal Title

      Toxicol Sci.

      Volume: 131 Pages: 116-127

    • Data Source
      KAKENHI-PROJECT-22580135
  • [Journal Article] Evaluating the role of rheumatoid factors for the development of rheumatoid arthritis in a mouse model with a newly established ELISA system.2010

    • Author(s)
      Tanaka, Y., Komori, H., Mori, S., Soga, Y., Tsubaki, T., Terada, M., Miyazaki, T., Fujino, T, Nakamura, S., Kanno, H., Sawasaki, T., Endo, Y., Nose, M.
    • Journal Title

      Tohoku Journal of Experimental Medicine

      Volume: 220 Pages: 199-206

    • NAID

      10027083539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590361
  • [Journal Article] Evaluating the role of rheumatoid factors for the development of rheumatoid arthritis in a mouse model with a newly established ELISA system.2010

    • Author(s)
      Tanaka Y, Komori H, Mori S, Soga Y, Tsubaki T, Terada M, Miyazaki T, Fujino T, Nakamura S, Kanno H, Sawasaki T, Endo Y, Nose M.
    • Journal Title

      Tohoku J Exp Med.

      Volume: 220(3) Pages: 199-206

    • NAID

      10027083539

    • URL

      https://www.jstage.jst.go.jp/article/tjem/220/3/220_3_199/_article

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590361
  • [Journal Article] Evaluating the role of rheumatoid factors in the development of rheumatoid arthritis in a mouse model with a newly established ELISA system.2010

    • Author(s)
      Tanaka Y., Komori H., Mori S., Soga Y., Tsubaki T., Terada M.,Miyazaki T., Fujino T., Nakamura S., Kanno H., Sawasaki S., Endo Y. and Nose M.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 220 Pages: 199-206

    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] 中枢神経系におけるアポE含有HDLの生成及び代謝メカニズム2013

    • Author(s)
      藤野貴広
    • Organizer
      日本農芸化学会2013年度大会
    • Place of Presentation
      仙台市
    • Year and Date
      2013-03-25
    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] アポEとその関連遺伝子の生物学的意義2012

    • Author(s)
      藤野貴広
    • Organizer
      第44回日本動脈硬化学会総会
    • Place of Presentation
      福岡市 (シンポジウム)
    • Year and Date
      2012-07-20
    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] ケラチノサイトのEGFによるダイオキシンの毒性発現抑制メカニズム2012

    • Author(s)
      藤野貴広、重川庸介、佐藤寛之、能丸幸治、岩田久人
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京都市
    • Year and Date
      2012-03-25
    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] ケラチノサイトのEGFによるダイオキシンの毒性発現抑制メカニズム2012

    • Author(s)
      藤野貴広
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京都女子大学(京都市)
    • Year and Date
      2012-03-25
    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] アポEとその関連遺伝子の生物学的意義2012

    • Author(s)
      藤野貴広
    • Organizer
      第44回日本動脈硬化学会総会
    • Place of Presentation
      福岡市
    • Invited
    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] Effect of apoE isoforms on ABCA1-mediated cholesterol efflux2011

    • Author(s)
      藤野貴広、劉明哲、植田和光、長尾耕治郎
    • Organizer
      日本農芸化学会2011年度大会
    • Place of Presentation
      京都市
    • Year and Date
      2011-03-26
    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] Effect of apoE isoforms on ABCA1-mediated cholesterol efflux2010

    • Author(s)
      藤野貴広、劉明哲、植田和光、長尾耕治郎
    • Organizer
      第42回日本動脈硬化学会総会
    • Place of Presentation
      岐阜市 (招待講演)
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-22580135
  • [Presentation] Fraser症候群様表現型を示す新規変異マウスの解析2008

    • Author(s)
      藤野 貴広
    • Organizer
      日本農芸化学会2008年度大会
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PROJECT-17380081
  • [Presentation] Molecular Characterization of Xenobiotics Acyl-CoA Synthetases2008

    • Author(s)
      藤野 貴広
    • Organizer
      グローバルCOE国際シンポジウム
    • Place of Presentation
      グローバルCOE国際シンポジウム
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17380081
  • [Presentation] Fraser症候群様表現型を示す新規変異マウスの解析2008

    • Author(s)
      藤野 貴広
    • Organizer
      日本農芸化学会2008年度大会
    • Place of Presentation
      日本農芸化学会2008年度大会
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17380081
  • [Presentation] Molecular Characterization of Xenobiotics Acyl-CoA Synthetases2008

    • Author(s)
      藤野 貴広
    • Organizer
      グローバルCOE国際シンポジウム
    • Place of Presentation
      愛媛県松山市
    • Data Source
      KAKENHI-PROJECT-17380081
  • [Presentation] 脳におけるアポEの糖鎖修飾とその機能2006

    • Author(s)
      藤野 貴広
    • Organizer
      日本農芸化学会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2006-03-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17380081
  • [Presentation] 糖及び脂質代謝におけるLDL受容体類似タンパク質5(LRP5)の機能2005

    • Author(s)
      藤野 貴広
    • Organizer
      第37回 日本動脈硬化学会総会シンポジウム
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2005-07-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17380081
  • 1.  NOSE Masato (70030913)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  HASEGAWA Hitoshi (40164826)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  MASUDA Seizo (50363263)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  MIYAZAKI Tatsuhiko (80239384)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  KURATA Mie (80423440)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MASUMOTO Junya (20334914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TANAKA Yuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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