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HASHIGUCHI Shuhei  橋口 周平

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… Alternative Names

Hashiguchi Shuhei  橋口 周平

HASHIGUCHI Syuhei  橋口 周平

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Researcher Number 40295275
Other IDs
External Links
Affiliation (Current) 2025: 鹿児島大学, 理工学域工学系, 助教
Affiliation (based on the past Project Information) *help 2015 – 2024: 鹿児島大学, 理工学域工学系, 助教
2015: 鹿児島大学, 工学部, 助教
2013 – 2015: 鹿児島大学, 理工学研究科, 助教
2011: 鹿児島大学, 大学院・理工学研究科(工学系), 助教
2011: 鹿児島大学, 大学院・理工学研究科, 助教 … More
2011: 鹿児島大学, 理工学研究科, 助教
2009 – 2011: 鹿児島大学, 理工学研究科(工学系), 助教
2007: Kagoshima University, Faculty of Engineering, Assistant Professor
1998 – 2006: 鹿児島大学, 工学部, 助手 Less
Review Section/Research Field
Principal Investigator
Veterinary medical science / Basic Section 42020:Veterinary medical science-related / 食の安全 / Virology / 生物・生体工学
Except Principal Investigator
Biological Sciences / Kansei informatics / Veterinary medical science / Living organism molecular science / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields … More / Medium-sized Section 61:Human informatics and related fields / Biofunction/Bioprocess / Drug development chemistry / 広領域 Less
Keywords
Principal Investigator
ファージディスプレイ / ワクチン / バクテリオファージ / ファージ療法 / アジュバント / 抗体 / ファージ / ミモトープ / M13 / プリオン … More / 抗体エンジニアリング / ヒト抗体 / M13ファージ / ファージセラピー / ファージワクチン / スギ花粉症 / ペプチドワクチン / Neurodegenerative disorders / Diagnosis / Food / Conformation / Antibody engineering / Prion / Human antibody / Phage display / 脳神経疾患 / 抗体エンジリアリング / 脳神経変性疾患 / 診断 / 食品 / コンフォメーション / MyD88 / ペプチド / 免疫 / 自然免疫 / ペプチドミミック / FcεRI / phage display library / アレルギー / IgE … More
Except Principal Investigator
ファージライブラリー / MCP-1 / ヒト抗体 / IL-6 / 分子設計 / メラノプシン / scFv / ペプチドミミック / ワクチン / 概日リズム / エイズ / CCR5 / ペプチドミメティックス / ipRGC / 明るさ / 色 / IL-8 / THP-1 / HMGB-1 / ペプチド / 抗体医薬 / 照明 / 乳房炎 / 薬剤耐性菌 / ファージセラピー / 黄色ブドウ球菌 / 緑膿菌 / バクテリオファージ / 細菌感染症 / ファージライブラリ / 感染防御 / IL-5 / インヒビター / 多原色光源装置 / 行動リズム / 時計遺伝子 / 光環境 / 分子時計 / 明るさ知覚 / mRGC / 瞳孔 / 明るさ感 / 光同調 / 視覚系 / 光受容器 / 瞳孔反応 / 非撮像系経路 / メラノプシン細胞 / 光 / 桿体細胞 / 錐体細胞 / ファージ / 獣医学 / エンドライシン / 抗生物質 / 耐性化 / MRSA / トレードオフ / ファージ耐性化 / 臨床試験 / 大腸菌 / 構造保持の確認 / 抗体提示の確認 / ベクターの改変 / ライブラリ構築戦略の変更 / 抗体提示の条件検討 / 立体構造保持の確認 / モジュール構造に適した構築法 / 1段階導入 / ライブラリ構築手法 / ライブラリ構築 / ライブラリの性能評価 / 非免疫グロブリンのライブラリ化 / モジュール構造を有するライブラリ / ライブラリ構築法 / タンパク質のライブラリ化 / inflammation / sepsis / human antibody phage library / 阻害剤 / 炎症 / 敗血症 / ヒト抗体ファージライブラリ / PHAGE LIBRARY / PEPTIDE ANTAGONIST / ANTIBODY ENGINEERING / MOLECULAR TARGETING / ANTIBODY DRUG / HUMAN ANTIBODY / ミミック / 抗体 / ヒト / ScFv / ペプチドアンタゴニスト / 抗体エンジニアリング / 分子標的医療 / Molecular design / Inhibitor / Human antibody / Peptide mimic / Phage library / IgE / TNFα / モノクロナル抗体 / 視知覚経路 / 桿体 / 錐体 / メラノプシン神経節細胞 / 角膜炎 / ウマ細菌性角膜炎 / オリゴマー / J20 / 受動免疫 / Aβ42 / TLR9 / MyD88 / アミロイドベーター / ミミックペプチド / 自然免疫 / M13ファージ / アルツハイマー認知症 / 免疫制御 / エントリーインヒビター / サイトカイン / 感染 / エントリーインフビター / HIV-1 / ケモカイン / T細胞 / コスティムユラ / 免疫応答 / CTLA4 Less
  • Research Projects

    (23 results)
  • Research Products

    (80 results)
  • Co-Researchers

    (34 People)
  •  メラノプシン細胞への選択的な刺激による概日リズム制御機能の解明

    • Principal Investigator
      辻村 誠一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Nagoya City University
  •  網膜メラノプシン細胞による生体への影響の解明:心理学・生物学・工学の手法を用いて

    • Principal Investigator
      辻村 誠一
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 61:Human informatics and related fields
    • Research Institution
      Nagoya City University
  •  Immunological mechanism of action of bacteriophage-based vaccines and its application for in vitro immunizationPrincipal Investigator

    • Principal Investigator
      Shuhei Hashiguchi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Kagoshima University
  •  Development and clinical application of next-generation phage therapy

    • Principal Investigator
      Iwano Hidetomo
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Veterinary medical science
    • Research Institution
      Rakuno Gakuen University
  •  Irradiance encoding process in the nonimage-forming pathway

    • Principal Investigator
      Tsujimura Sei-ichi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kansei informatics
    • Research Institution
      Nagoya City University
      Kagoshima University
  •  Immunological mechanism for M13-phage-based vaccine immunogenicity and its application.Principal Investigator

    • Principal Investigator
      Hashiguchi Shuhei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Kagoshima University
  •  Design and basic reserch of novel antibody using Leucine Rich Repeat scaffold.

    • Principal Investigator
      Yoshinaga Keisuke
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      National Institute of Technology, Kumamoto College
  •  Contribution of melanopsin ganglion cells to visual pathway

    • Principal Investigator
      TSUJIMURA Sei-ichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kansei informatics
    • Research Institution
      Kagoshima University
  •  Research of phage therapy and phage vaccine for bacterial infectious diseases.

    • Principal Investigator
      IWANO Hidetomo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Rakuno Gakuen University
  •  M13 phage as a vaccine vehclePrincipal Investigator

    • Principal Investigator
      Hashiguchi Shuhei
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Kagoshima University
  •  M13 bacteriophage-based vaccine design for prion.Principal Investigator

    • Principal Investigator
      HASHIGUCHI Shuhei
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Kagoshima University
  •  Amyloid beta-42-mimotope displaying M13 bacteriophage for vaccine vehicle of Alzheimer's disease

    • Principal Investigator
      SUGIMURA Kazuhisa
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Kagoshima University
  •  Basic studies for development of inhibitor to target nuclear inflammatory cytokine related with sepsis

    • Principal Investigator
      ITO Yuji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kagoshima University
  •  Prion-conformation-specific human antibodies established from phage display library.Principal Investigator

    • Principal Investigator
      HASHIGUCHI Shuhei
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      食の安全
    • Research Institution
      Kagoshima University
  •  Study on molecular targeting using phage dispky library

    • Principal Investigator
      SUGIMURA Kazuhisa
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Kagoshima University
  •  抗体エンジニアリングによる免疫制御分子の開発Principal Investigator

    • Principal Investigator
      橋口 周平
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      生物・生体工学
    • Research Institution
      Kagoshima University
  •  エイズ感染阻子分子の分子設計法の基礎研究

    • Principal Investigator
      杉村 和久
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  ファージディスプレイライブラリーを用いた感染防御と免疫制御法の開発

    • Principal Investigator
      杉村 和久
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  エイズ感染阻止分子の分子設計法の基礎研究

    • Principal Investigator
      杉村 和久
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  免疫制御分子の機能性ドメインミミックの分子設計と免疫制御

    • Principal Investigator
      杉村 和久
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  エイズワクチンの活性強化分子の分子設計法の基礎研究

    • Principal Investigator
      杉村 和久
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  Molecular design of functional domain-mimics of receptors and ligands

    • Principal Investigator
      SUGIMURA Kazuhisa
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      Kagoshima University
  •  エイズワクチンの活性強化分子の分子設計法の基礎研究

    • Principal Investigator
      SUGIMURA Kazuhisa
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University

All 2021 2018 2017 2016 2015 2013 2012 2011 2010 2009 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] 医学のあゆみ、細菌に感染するバクテリオファージを担体とするファージワクチン設計2021

    • Author(s)
      橋口周平
    • Total Pages
      6
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-19K06386
  • [Book] 生化学:ファージディスプレイとBeyond antibody:-抗体様分子による分子標的-2010

    • Author(s)
      橋口周平、伊東祐二、田中孝一、松木園美穂、村岡賢、杉村和久
    • Publisher
      社団法人日本生化学会
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Book] 生化学:ファージディスプレイとBeyond antibody :~抗体様分子による分子標的~2010

    • Author(s)
      橋口周平, 伊東祐二, 田中孝一, 松木園美穂, 村岡賢, 杉村和久
    • Publisher
      社団法人日本生化学会
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Book] Prions : Food and Drug Safety(Ed T.Kitamoto)2005

    • Author(s)
      Shuhei Hashiguchi et al.
    • Total Pages
      2
    • Publisher
      Springer
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16613008
  • [Book] Prions : Food and Drug Safety (Ed.T.Kitamoto)2005

    • Author(s)
      Shuhei Hashiguchi et al.
    • Total Pages
      2
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-16613008
  • [Book] 検査と技術2004

    • Author(s)
      橋口周平
    • Total Pages
      4
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-16613008
  • [Journal Article] Development of Universal Phage Vaccine Displaying Extracellular Domains of M2e Derived from Human Influenza A Viruses2015

    • Author(s)
      Ryohei Shioya, Ryuji Miyahara, Yoshitsugu Shoji, Kazuhisa Sugimura, Shuhei Hashiguchi
    • Journal Title

      Peptide Science

      Volume: 2014 Pages: 265-266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Journal Article] Cytokine mRNA profiling and the proliferative response of bovine peripheral blood mononuclear cells to Mycoplasma bovis.2015

    • Author(s)
      Gondaira S, Higuchi H, Iwano H, Nakajima K, Kawai K, Hashiguchi S, Konnai S, Nagahata H.
    • Journal Title

      Vet Immunol Immunopathol.

      Volume: 165 Issue: 1-2 Pages: 45-53

    • DOI

      10.1016/j.vetimm.2015.03.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25292182, KAKENHI-PROJECT-26450432, KAKENHI-PROJECT-25257415
  • [Journal Article] Cytokine mRNA profiling and the proliferative response of bovine peripheral blood mononuclear cells to Mycoplasma bovis.2015

    • Author(s)
      Gondaira, S., Higuchi, H., Iwano, H., Nakajima, K., Kawai, K., Hashiguchi, S., Konnai, S., and Nagahata, H.
    • Journal Title

      Vet Immunol Immunopathol.

      Volume: 165 Pages: 45-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Journal Article] 分子標的素子デザインにおけるファージライブラリー法2015

    • Author(s)
      橋口周平、宮原隆二、岸本聡、伊東祐二
    • Journal Title

      日本生物工学会誌

      Volume: 93 Pages: 289-292

    • Data Source
      KAKENHI-PROJECT-25450427
  • [Journal Article] Desensitization vaccine strategy using M13 phage whose g8p displays a B cell IgG epitope of Cry j 1 as a major allergen of Japanese cedar pollen2012

    • Author(s)
      Kai Satomi, Shuhei Hashiguchi, Kazuhisa Sugimura
    • Journal Title

      Peptide Science 2011

      Pages: 269-270

    • Data Source
      KAKENHI-PROJECT-22790435
  • [Journal Article] Direct evidence of generation and accumulation ofβ-sheet-rich prion protein in scrapie-infected neuroblastoma cells with a human IgG1 antibody specific for the b-form prion protein2012

    • Author(s)
      Toshiya Kubota, Yuta Hamazoe, Shuhei Hashiguchi, Daisuke Ishibashi, Kazuyuki Akasaka, Noriyuki Nishida, Shigeru Katamine, Suehiro Sakaguchi, Ryota Kuroki, Toshihiro Nakashima, and Kazuhisa Sugimura
    • Journal Title

      J. Biol. Chem

      Volume: 287 Pages: 14023-14039

    • URL

      http://www.jbc.org/content/287/17/14023.full

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Journal Article] Direct evidence of generation and accumulation of β-sheet-rich prion protein in ScN2a cells de novo illuminated by human IgG1 antibody recognizing β-form but not α-form of prion protein2012

    • Author(s)
      Toshiya Kubota, Yuta Hamazoe, Shuhei Hashiguchi, Daisuke Ishibashi, Kazuyuki Akasaka, Noriyuki Nishida, Shigeru Katamine, Suehiro Sakaguchi, Ryota Kuroki, Toshihiro Nakashima, Kazuhisa Sugimura.
    • Journal Title

      The Journal of biological chemistry

      Volume: 287巻 Issue: 17 Pages: 14023-14039

    • DOI

      10.1074/jbc.m111.318352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790435, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-24591482
  • [Journal Article] Direct evidence of generation and accumulation of β-sheet-rich prion protein in scrapie-infected neuroblastoma cells with a human IgG1 antibody specific for the b-form prion protein2012

    • Author(s)
      Toshiya Kubota, Yuta Hamazoe, Shuhei Hashiguchi, Daisuke Ishibashi, Kazuyuki Akasaka, Noriyuki Nishida, Shigeru Katamine, Suehiro Sakaguchi, Ryota Kuroki, Toshihiro Nakashima, Kazuhisa Sugimura
    • Journal Title

      J.Biol.Chem.

      Volume: 287 Pages: 14023-14039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Journal Article] Desensitization vaccine strategy using M13 phage whose g8p displays a B cell IgG epitope of Cry j 1 as a major allergen of Japanese cedar pollen2012

    • Author(s)
      Kai S, Hashiguchi S, et al
    • Journal Title

      Peptide Science 2011

      Pages: 269-270

    • Data Source
      KAKENHI-PROJECT-22790435
  • [Journal Article] Immunological basis of M13 phage vaccine : Regulation under MyD88 and TLR9 signaling2011

    • Author(s)
      Shuhei Hashiguchi, Yuya Yamaguchi, Osamu Takeuchi, Shizuo Akira, Kazuhisa Sugimura
    • Journal Title

      Biochemical and biophysical research communications

      Volume: 402巻 Issue: 1 Pages: 19-22

    • DOI

      10.1016/j.bbrc.2010.09.094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Journal Article] A mimotope peptide of Aβ42 fibril-specific antibodies with Aβ42 fibrillation inhibitory activity induces anti-Aβ42 conformer antibody response by a displayed form on an M13 phage in mice2011

    • Author(s)
      Koichi Tanaka, Masaaki Nishimura, Yuya Yamaguchi, Shuhei Hashiguchi, Sho Takiguchi, Makoto Yamaguchi, Haruna Tahara, Takuma Gotanda, Risa Abe, Yuji Ito, Kazuhisa Sugimura
    • Journal Title

      J. Neuroimmunology

      Volume: 236 Pages: 27-38

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21641049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Journal Article] A mimotope peptide of Aβ42 fibril-specific antibodies with Aβ42 fibrillation inhibitory activity induces anti-Aβ42 conformer antibody response by a displayed form on an M13 phage in mice2011

    • Author(s)
      Koichi Tanaka, Masaaki Nishimura, Yuya Yamaguchi, Shuhei Hashiguchi, Sho Takiguchi, Makoto Yamaguchi, Haruna Tahara, Takuma Gotanda, Risa Abe, Yuji Ito, Kazuhisa Sugimura
    • Journal Title

      J.Neuroimmunology

      Volume: 236 Pages: 27-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Journal Article] Essential role of MyD88 in humoral response to M13 bacteriophage in mice and negative role of TLR9 in IgG1 response.2010

    • Author(s)
      Hashiguchi S, Yamaguchi Y, Takeuchi O, Akira S, Sugimura K.
    • Journal Title

      International Immunology

      Volume: 22 : Supplement Number 1

    • Data Source
      KAKENHI-PROJECT-22790435
  • [Journal Article] ファージディスプレイとBeyond antibody :~抗体様分子による分子標的~2010

    • Author(s)
      橋口周平、伊東祐二、田中孝一、松木園美穂、村岡賢、杉村和久
    • Journal Title

      生化学

      Volume: 82 Pages: 710-726

    • NAID

      10027502225

    • Data Source
      KAKENHI-PROJECT-21310144
  • [Journal Article] Immunological basis of M13 phage vaccine : Regulation under MyD88 and TLR9 signaling.2010

    • Author(s)
      Shuhei Hashiguchi, Yuya Yamaguchi, Osamu Takeuchi, Shizuo Akira, Kazuhisa Sugimura
    • Journal Title

      BBRC

      Volume: 402 Pages: 19-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Journal Article] Characterization of Human Single-Chain Antibodies Against Highly Pathogenic Avian Influenza H5N1 Viruses : Mimotope and Neutralizing Activity.2010

    • Author(s)
      JiuPian Yang, Reiko Yoshida, Yuji Ito, Yuki Kariya, Xu Zhang, Shuhei Hashiguchi, Toshihiro Nakashima, Yasuo Suda, Ayato Takada, Kazuhisa Sugimura.
    • Journal Title

      J.Biochem.

      Volume: 148 Pages: 504-515

    • NAID

      10027879101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Journal Article] Immunological basis of M13 phage vaccine : Regulation under MyD88 and TLR9 signaling.2010

    • Author(s)
      Hashiguchi S, Yamaguchi Y, Takeuchi O, Akira S, Sugimura K
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 402 Pages: 19-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Journal Article] Prion-conformation-specific human antibodies established from phage display library.2005

    • Author(s)
      Shuhei Hashiguchi, Mayumi Yamamoto, Sho Kitamoto, Toshihiro Nakashima, Hitoki Yamanaka, Daisuke Ishibashi, Suehiro Sakaguchi, Shigeru Katamine, Yyji Ito, Kazuhisa Sugimura
    • Journal Title

      Prions : Food and Drug Safety (Ed.T.Kitamoto)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16613008
  • [Journal Article] Binding Epitope of Human Anti-FcεRI α-chain Receptor Antibody, RE51, with the Blocking Activity on IgE-mediated Histamine Release2004

    • Author(s)
      橋口周平(他、3名)
    • Journal Title

      Immunology2004(Ed : Medimond S.r.l.)

      Pages: 541-544

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15310152
  • [Journal Article] Binding Epitope of Human Anti-FcεRI α-chain Receptor Antibody, RE51,with the Blocking Activity on IgE-mediated Histamine Release2004

    • Author(s)
      橋口周平(他, 3名)
    • Journal Title

      Immunology2004(Ed : Medimond S.r.l.)

      Pages: 541-544

    • Data Source
      KAKENHI-PROJECT-15310152
  • [Journal Article] 抗体エンジニアリングと診断技術2004

    • Author(s)
      橋口 周平(他, 1名)
    • Journal Title

      検査と技術(医学書院) 32(11)

      Pages: 1319-1322

    • Data Source
      KAKENHI-PROJECT-15310152
  • [Journal Article] 抗体エンジニアリングと診断技術2004

    • Author(s)
      橋口 周平(他、1名)
    • Journal Title

      検査と技術(医学書院) 32(11)

      Pages: 1319-1322

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15310152
  • [Journal Article] Human FcεRIα-specific human single-chain Fv (scFv) antibody with antagonistic activity toward IgE/FceRIα-binding2003

    • Author(s)
      橋口 周平(他、7名)
    • Journal Title

      J.Biochem. 133(1)

      Pages: 43-49

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15310152
  • [Journal Article] Human Anti-FcεRI α-specific human single-chain Fv (scFv) antibody with antagonistic activity toward IgE/FceRIα-binding2003

    • Author(s)
      橋口 周平(他, 7名)
    • Journal Title

      J.Biochem. 133(1)

      Pages: 43-49

    • Data Source
      KAKENHI-PROJECT-15310152
  • [Presentation] Preferential uptake of M13 phage vaccine by murine macrophages without the production of proinflammatory cytokines.2018

    • Author(s)
      Kei Nakagawaji, Shuhei Hashiguchi, Akikazu Murakami, Masahito Hashimoto
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] M13ファージペプチドワクチンの設計法:抗原提示方法の改良による抗原性の増強2017

    • Author(s)
      宮原隆二、樋口雄介、橋本雅仁、橋口周平
    • Organizer
      平成29年度日本生化学会九州支部例会
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] Diurnal variations in humoral immune response against bacteriophage in mice2017

    • Author(s)
      橋口周平、辻村誠一
    • Organizer
      第24回日本時間生物学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] M13ファージを担体としたワクチンによる自己抗体誘導の可能性2017

    • Author(s)
      中川路けい、宮原隆二、橋本雅仁、橋口周平
    • Organizer
      平成29年度日本生化学会九州支部例会
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] 抗原エピトープ特異的IgG抗体を誘導するファージワクチンの分子設計法2017

    • Author(s)
      宮原隆二、篠崎太亮、中西美加、中川路けい、橋本雅仁、橋口周平
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] Immunogenicity of M13 phage vaccine displaying N-terminal region of amyloid beta peptide: comparison of M13 phage vaccine expressed as g3p fusion and g8p fusion2016

    • Author(s)
      Ryuji Miyahara, Akiko Shimotsu, Yui Matsushita, Mai Tsukada, Masahito Hashimoto, Kazuhisa Sugimura, Shuhei Hashiguchi
    • Organizer
      International Congress of Immunology 2016
    • Place of Presentation
      Melbourne (Australia)
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] M13ファージペプチドワクチンの設計法:抗原分子の提示方法の違いと抗原性2016

    • Author(s)
      宮原隆二、下津尭子、松下由依、篠崎太亮、橋本雅仁、橋口周平
    • Organizer
      ファージ・環境ウイルス研究合同シンポジウム
    • Place of Presentation
      JAMSTEC横浜本部(神奈川県横須賀市)
    • Year and Date
      2016-10-21
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] M13 phage vaccine for Alzheimer’s disease that induce T-cell independent IgG response against Aβ peptide2016

    • Author(s)
      Ryuji Miyahara, Yui Matsushita, Akiko Shimotsu, Taisuke Shinozaki, Masahito Hashimoto, Kazuhisa Sugimura, Shuhei Hashiguchi
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄 コンベンションセンター、ラグナガーデンホテル(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-16K08024
  • [Presentation] M13ファージを担体とした抗Aβ抗体を誘導するワクチン開発2015

    • Author(s)
      宮原隆二、庄司恵二、塩屋亮平、下津尭子、松下由依、杉村和久、橋口周平
    • Organizer
      第34回日本認知症学会学術集会
    • Place of Presentation
      リンクステーションホール青森・ホテル青森 (青森県・青森市)
    • Year and Date
      2015-10-02
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] アジュバントの添加を必要としない繊維状ファージ (M13) を担体としたファージワクチンの開発2015

    • Author(s)
      橋口周平
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学獣医学部 (青森県・十和田市)
    • Year and Date
      2015-09-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] スギ花粉アレルゲンCry j 1のIgE結合エピトープを提示したファージワクチンによる脱感作効果の検討2015

    • Author(s)
      橋口周平、泊大介、宮原隆二、塩屋亮平、杉村和久
    • Organizer
      第64回日本アレルギー学会学術大会
    • Place of Presentation
      グランドプリンスホテル新高輪 国際館パミール (東京都・港区高輪)
    • Year and Date
      2015-05-26
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] Immunogenicity of M13 phage vaccine displaying the extracellular domain of matrix protein 2 (M2e) of human influenza A virus.2015

    • Author(s)
      Shuhei Hashiguchi, Ryuji Miyahara, Ryohei Shioya, Yui Matsushita, Akiko Shimotsu, Kazuhisa Sugimura
    • Organizer
      第44回日本免疫学会学術集会
    • Place of Presentation
      札幌コンベンションセンター (北海道・札幌市)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] M13 bacteriophage for a vaccine vehicle.2013

    • Author(s)
      Shuhei Hashiguchi
    • Organizer
      Phage2013
    • Place of Presentation
      Oxford, UK
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] Characterization of antibody responses to M13 phage vaccine: MyD88-dependent and T-cell independent IgG subclass responses.2013

    • Author(s)
      Shuhei Hashiguchi, Masaya Toyonaga, Yoshitsugu Shoji, Takuma Gotanda, Kazuhisa Sugimura.
    • Organizer
      International Congress of Immunology 2013
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] Medical application of peptide-displaying M13 phage for vaccine vehicle.2013

    • Author(s)
      Masaya Toyonaga, Shoji Yoshitsugu, Shuhei Hashiguchi, Kazuhisa Sugimura.
    • Organizer
      4th Asia-Pacific International Peptide Symposium and 50th Japanese Peptide Symposium (APIPS2013)
    • Place of Presentation
      大阪市
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] Immunological characterization of M13 phage vaccine.2013

    • Author(s)
      Sugimura K, Osako T, Kawabata S, Miyahara R, Tsurumaru T, Oda R, Tomari D, Shioya R, Hashiguchi S.
    • Organizer
      International Congress of Immunology 2013
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] Immunological characterization of M13 phage vaccine: Possible involvement of Marginal Zone B cells to generate IgG response and germinal centers in response to M13 phage.2013

    • Author(s)
      Shuhei Hashiguchi, Masaya Toyonaga, Yoshitsugu Shoji, Kazuhisa Sugimura.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] M13ファージワクチンデザインのためのM13ファージのin vivo動態の解析2013

    • Author(s)
      豊永将也、庄司恵二、末広一彦、中倉大彰、中島麻美、徳永麗雅、橋口周平、杉村和久
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] アルツハイマー病モデルマウス(J20)脳内での、繊維状アミロイドβ(Aβ)に特異的な抗体(B7)によるAβプラークの免疫組織学的解析2011

    • Author(s)
      川畑壮大朗、安部梨沙、田中孝一、大迫哲平、橋口周平、鈴木賢太朗、山田源、中島敏博、中河史朗、杉村和久
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Amyloid beta42-mimotope-displaying M13 phage induce anti-amyloid beta42antibody without adjuvant2011

    • Author(s)
      大迫哲平、安部梨沙、川畑壮大朗、田中孝一、五反田卓摩、橋口周平、中河志朗、杉村和久
    • Organizer
      第40回日本免疫学会学術集会記録
    • Place of Presentation
      千葉,幕張メッセ
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Strong innate immunity to M13 bacteriophage : Implication for vaccine development2011

    • Author(s)
      Shuhei Hashiguchi, Takuma Gotanda, Yuta Hamazoe, Kazuhisa Sugimura
    • Organizer
      第40回日本免疫学会学術集会記録
    • Place of Presentation
      千葉,幕張メッセ
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Amyloid beta 42-mimotope-displaying M13 phage induce anti-amyloid beta 42 antibody without adjuvant2011

    • Author(s)
      Kazuhisa Sugimura, Risa Abe, Sotaro Kawabata, Teppei Osako, Takuma Gotanda, Shuhei Hashiguchi, Shiro Nakagawa
    • Organizer
      Alzheimer's Association International Conference on Alzheimer's Disease 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-17
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Strong Innate Immunity to M13 Bacteriophage : Implication for Vaccine Development2011

    • Author(s)
      Shuhei Hashiguchi, Takuma Gotanda, Yuta Hamazoe, Tsuyoshi Tsurumaru, Kazuhisa Sugimura
    • Organizer
      5th Vaccine and ISV Annual Global Congress
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Monoclonal human IgG1 specific to Prion2011

    • Author(s)
      Kubota T, Hamazoe Y, Hashiguchi S, et al
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Amyloid beta-42-mimotope displaying M13 bacteriophage for Vaccine vehicle of Alzheimer's disease2011

    • Author(s)
      Kazuhisa Sugimura, Shuhei Hashiguchi, Teppei Osako, Sotaro Kawabata, Risa Abe, Shiro Nakagawa
    • Organizer
      5th Vaccine and ISV Annual Global Congress
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] アルツハイマー病モデルマウス(J20)脳内での、線維状アミロイドβ(Aβ)に特異的な抗体(B7)によるAβプラークの免疫組織学的解析2011

    • Author(s)
      川畑壮大朗、安部梨沙、田中孝一、大迫哲平、橋口周平、鈴木賢太郎、山田源、中島敏博、中河志朗、杉村和久
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      兵庫,神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Amyloid beta-42-mimotope displaying M13 bacteriophage for vaccine vehicle of Alzheimer's disease2011

    • Author(s)
      Kazuhisa Sugimura, Shuhei Hashiguchi, TEppei Osako, Sotaro Kawabata, Risa Abe, Shiro Nakagawa
    • Organizer
      5th Vaccine and ISV Annual Global Congress
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Amyloid Beta-42-Mimotope Displaying M13 Bacteriophage for Vaccine Vehicle of Arzheimer's Disease2011

    • Author(s)
      Kazuhisa Sugimura, Shuhei Hashiguchi, Teppei Osako, Sotaro Kawabata, Risa Abe, Shiro Nakagawa
    • Organizer
      5th Vaccine and ISV Annual Global Congress
    • Place of Presentation
      Seattle
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] M13 bacteriophage for vaccine vehicle of Alzheimer's disease2011

    • Author(s)
      Kazuhisa Sugimura, Shuhei Hashiguchi, Teppei Osako, Kawabata Sotaro, Risa Abe
    • Organizer
      1st Oxford International bacteriophage conference, Phage2011 : Bacteriophage Application
    • Place of Presentation
      Oxford, UK
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] M13 bacteriophage for vaccine vehicle of Alzheimer's disease2011

    • Author(s)
      Kazuhisa Sugimura, Shuhei Hashiguchi, Teppei Osako, Sotaro Kawabata, Risa Abe
    • Organizer
      1st Oxford International Bacteriophage Conference, Phage 2011
    • Place of Presentation
      St Hilda's college Oxford University
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Strong innate immunity to M13 bacteriophage2011

    • Author(s)
      Hashiguchi S, Gotannda T, et al
    • Organizer
      第40回日本免疫学会総会・学術集会記録
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Strong Innate Immunity to M13 Bacteriophage : Implication for Vaccine Development2011

    • Author(s)
      Shuhei Hashiguchi, Takuma Gotanda, Yuta Hamazoe, Tsuyoshi Tsurumaru, Kazuhisa Sugimura
    • Organizer
      5th Vaccine and ISV Annual Global Congress
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Strong innate immunity to M13 bacteriophage : Implication for vaccine development2011

    • Author(s)
      Shuhei Hashiguchi, Takuma Gotanda, Hamazoe Yuta, Kazuhisa Sugimura
    • Organizer
      第40回日本免疫学会総会・学術集会記録
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Monoclonal human IgG1 specific to Prion2011

    • Author(s)
      Toshiya Kubota, Yuta Hamazoe, Shuhei, Hashiguchi, Daisuke Ishibashi, Noriyuki Nishida, Suehiro Sakaguchi, Kazuhisa Sugimura
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] M13バクテリオファージ免疫におけるTLRファミリー分子の役割について2010

    • Author(s)
      田原春菜、橋口周平、山口雄也、竹内理、審良静男、杉村和久
    • Organizer
      BMB2010第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Immunological basis of M13 phage vaccines : an effective vaccine design tested in a mouse model of Alzheimer's disease.2010

    • Author(s)
      Hashiguchi S, Yamaguchi Y, Tahara H, Yamada T, Kai S, Abe R, Tanaka K, Sugimura K.
    • Organizer
      5th International Peptide Symposium
    • Place of Presentation
      京都市
    • Year and Date
      2010-12-06
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] M13バクテリオファージが誘導するIgG抗体応答はMyD88に依存する2010

    • Author(s)
      橋口周平、山口雄也、竹内理、審良静男、杉村和久
    • Organizer
      日本生化学会九州支部例会
    • Place of Presentation
      鹿児島県鹿児島市
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Amyloid beta42-mimotope-displaying M13 phage induce anti-amyloid beta42antibody without adjuvant2010

    • Author(s)
      Kazuhisa Sugimura, Risa Abe, Sotaro Kawabata, Teppei Osako, Takuma Gotanda, Shuhei Hashiguchi, Shiro Nakagawa
    • Organizer
      Alzheimer's Association International Conference on Alzheimer's Disease
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Essential role of MyD88 in humoral response to M13 bacteriophage in mice and negative role of TLR9 in IgG1 response.2010

    • Author(s)
      Hashiguchi S, Yamaguchi Y, Takeuchi O, Akira S, Sugimura K.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] M13バクテリオファージ免疫におけるTLRファミリー分子の役割について2010

    • Author(s)
      田原春菜, 橋口周平, 山口雄也, 竹内理, 審良静男、杉村和久
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Essential role of MyD88 in humoral response to M13 bacteriophage in mice and negative role of TLR9 in IgG1 response.2010

    • Author(s)
      Hashiguchi S, Yamaguchi Y, Takeuchi O, Akira S, Sugimura K.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      神戸市
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Immunological basis of phage vaccine as an experimental model using Alzheimer's disease model mice, J20 immunized with a mimotope-phage clone selected by a fibrillar Abeta42-specific antibody.2010

    • Author(s)
      Yuya Yamaguchi, Shuhei Hashiguchi, Koichi Tanaka, Risa Abe, Kazuhisa Sugimura.
    • Organizer
      The Immunotherapeutics and vaccine summit
    • Place of Presentation
      Cambridge, MA
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] Immunological basis of M13 phage vaccines : an effective vaccine design tested in a mouse model of Alzheimer's disease2010

    • Author(s)
      Shuhei Hashiguchi, Yuya Yamaguchi, Haruna Tahara, Takashi Yamada, Satomi Kai, Risa Abe, Koichi Tanaka, Kazuhisa Sugimura
    • Organizer
      5th International Peptide Symposium
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] M13バクテリオファージ免疫におけるTLRファミリー分子の役割について2010

    • Author(s)
      田原春菜、橋口周平、山口雄也、竹内理、審良静男、杉村和久
    • Organizer
      BMB2010第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Immunological basis of M13 phage vaccines : an effective vaccine design tested in a mouse model of Alzheimer's disease.2010

    • Author(s)
      Hashiguchi S, Yamaguchi Y, Tahara H, Yamada T, Kai S, Abe R, Tanaka K, Sugimura K.
    • Organizer
      5th International Peptide Symposium
    • Place of Presentation
      京都府京都市
    • Year and Date
      2010-12-06
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] Essential role of MyD88 in humoral response to M13 bacteriophage in mice and negative role of TLR9 in IgG1 response2010

    • Author(s)
      Shuhei Hashiguchi, Yuya Yamaguchi, Osamu Takeuchi, Shizuo Akira, Kazuhisa Sugimura
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] M13バクテリオファージが誘導するIgG抗体応答はMyD88に依存する2010

    • Author(s)
      橋口周平、山口雄也、竹内理, 審良静男、杉村和久
    • Organizer
      日本生化学会九州支部例会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-22790435
  • [Presentation] アミロイドベータ1-42ミモトープをディスプレイしたM13ファージが誘導する免疫応答の解析2009

    • Author(s)
      山口雄也, 橋口周平, 永尾宏子, 山田昴, 杉村和久
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21310144
  • [Presentation] M13バクテリオファージが誘導する免疫応答の解析

    • Author(s)
      庄司恵二、塩屋亮平、宮原隆二、杉村和久、橋口周平
    • Organizer
      第5回ファージ研究会
    • Place of Presentation
      三重大学生物資源学部大講義室(三重県・津市)
    • Year and Date
      2014-09-04 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-25450427
  • [Presentation] ファージワクチンの基礎的研究:M13ファージ蛋白を用いた特異的免疫応答の解析

    • Author(s)
      庄司恵二、橋口周平、塩屋亮平、宮原隆二、杉村和久
    • Organizer
      平成26年度日本生化学会九州支部例会
    • Place of Presentation
      九州大学コラボステーションI(福岡県・福岡市)
    • Year and Date
      2014-05-17 – 2014-05-18
    • Data Source
      KAKENHI-PROJECT-25450427
  • 1.  SUGIMURA Kazuhisa (80127240)
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    # of Collaborated Products: 23 results
  • 2.  ITO Yuji (60223195)
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  • 19.  YOSHIZAKI Kazuyuki (90144485)
    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 0 results
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