Hirose Takashi 廣瀬敬

… Alternative Names

HIROSE Takashi 慶瀬敬

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Researcher Number	40307038
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2013: 昭和大学, 内科学講座呼吸器内科学分野, 准教 2013: 昭和大学, 医学部・呼吸器アレルギー内科, 准教授 2013: 独立行政法人国立病院機構東京病院(臨床研究部), その他部局等, その他 2010 – 2013: 昭和大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Applied pharmacology Except Principal Investigator General pharmacology / Clinical oncology
Keywords	Principal Investigator ファーマコゲノミクス Except Principal Investigator EGFR / FADD / MET / c-MET / EGFR阻害剤 / crosstalk signal / 薬剤耐性 / EGFR-TKI / TRAIL … More / 扁平上皮癌 / 肺癌 / ADAM17 / 上皮成長因子受容体 / 喫煙 / 肺扁平上皮癌 / 扁平上皮肺癌 / 喫煙者肺癌 Less

Elucidation of trans-activation mechanism from TRAIL receptor to EGFR
- Principal Investigator
  
  OHMORI Tohru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Showa University
Association of pharmacokinetics or pharmacogenomics with toxicity of erlotinib in patients with advanced non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  HIROSE Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tokyo National Hospital (Clinical research)
  Showa University
The role of ADAM17 in squamous cell lung cancer
- Principal Investigator
  
  SIRAI Takao
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Showa University

All 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] 進行再発非小細胞肺癌に対するセカンドライン化学療法の検討2012
- Author(s)
  白井崇生, 慶瀬敬, 村田泰規, 大木康成, 楠本壮三郎, 杉山智英, 石田博雄, 中属賢尚, 大西司, 山岡利光, 大森亨, 奥田健太郎
- Journal Title
  
  昭和医学会雑誌
  
  Volume: 72巻4号 Pages: 446-452
- NAID
  130003378205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer.2012
- Author(s)
  Hirose T
- Journal Title
  
  Oncology Research
  
  Volume: 20(2-3) Pages: 131-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer.2012
- Author(s)
  Hirose T, Murata Y, Oki Y, Sugiyama T, Kusumoto S, Ishida H, Shirai T, Nakashima M, Yamaoka T, Okuda K, Ohnishi T, Ohmori T.
- Journal Title
  
  Oncology Research
  
  Volume: 20 Pages: 131-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer2012
- Author(s)
  Hirose T, Yamaoka T, Ohmori T. et al
- Journal Title
  
  Oncol Res
  
  Volume: 20(2-3) Pages: 131-137
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease2012
- Author(s)
  Okuda K, Hirose T, Yamaoka T, Ohmori T. et al
- Journal Title
  
  Anticancer Res
  
  Volume: 32(2) Pages: 5475-5480
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease2012
- Author(s)
  Okuda K, Hirose T, Oki Y, Murata Y, Kusumoto S, Sugiyama T, Ishida H, Shirai T, Nakashima M, Yamaoka T, Ohnishi T, Ohmori T
- Journal Title
  
  Anticancer Res.
  
  Volume: 32(12) Pages: 5475-80
- URL
  http://ar.iiarjournals.org/content/32/12/5475.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer2012
- Author(s)
  Hirose T, Murata Y, Oki Y, Sugiyama T, Kusumoto S, Ishida H, Shirai T, Nakashima M, Yamaoka T, Okuda K, Ohnishi T, Ohmori T
- Journal Title
  
  Oncol Res.
  
  Volume: 20(2-3) Pages: 131-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease.2012
- Author(s)
  Okuda K, Hirose T, Oki Y, Murata Y, Kusumoto S, Sugiyama T, Ishida H, Shirai T, Nakashima M, Yamaoka T, Ohnishi T, Ohmori T.
- Journal Title
  
  Anticancer Researcg
  
  Volume: 32 Pages: 1337-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II trial of the combination of carboplatin and irinotecan in elderly patients with small-cell lung cancer.2011
- Author(s)
  Murata Y, Hirose T, Ohmori T et al
- Journal Title
  
  Eur J Cancer
  
  Volume: 47 Pages: 1336-42
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21458256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Myelosuppression induced by concurrent chemoradiotherapy as a prognostic factor for patients with locally advanced non-small cell lung cancer2011
- Author(s)
  Kishida Y, Hirose T, Shirai T, Sugiyama T, Kusumoto S, Yamaoka T, Okuda K, Adachi M, Nakamura A
- Journal Title
  
  Oncol Lett.
  
  Volume: 2(5) Pages: 949-955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Phase II trial of amrubicin and carboplatin in patients with sensitive or refractory relapsed small-cell lung cancer2011
- Author(s)
  Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Lung Cancer
  
  Volume: (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II study of S-1, a novel oral fluoropyrimidine, and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer.2011
- Author(s)
  Oki Y, Hirose T, Ohmori T et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 67 Pages: 791-7
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20556612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II trial of amrubicin and carboplatin in patients with sensitive or refractory relapsed small -cell lung cancer2011
- Author(s)
  Hirose T, Nakashima M, Shirai T, Kusumoto S, Sugiyama T, Yamaoka T, Okuda K, Ohnishi T, Ohmori T, Adachi M
- Journal Title
  
  Lung Cancer
  
  Volume: 73(3) Issue: 3 Pages: 345-50
- DOI
  10.1016/j.lungcan.2010.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Phase II study of S-1, a novel oral fluoropyrimidine, and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer2011
- Author(s)
  Oki Y, Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 67(4) Pages: 791-797
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II trial of the combination of carboplatin and irinotecan in elderly patients with small -cell lung cancer2011
- Author(s)
  Murata Y, Hirose T, Yamaoka T, Shirai T, Okuda K, Sugiyama T, Kusumoto S, Nakashima M, Ohmori T, Adachi M
- Journal Title
  
  Eur J Cancer
  
  Volume: 47(9) Issue: 9 Pages: 1336-42
- DOI
  10.1016/j.ejca.2011.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Phase II trial of the combination of carboplatin and irinotecan in elderly patients with small-cell lung cancer2011
- Author(s)
  Murata Y, Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Eur J Cancer
  
  Volume: 47(9) Pages: 1336-1342
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Evaluation of the efficacy and safety of the combination of gemcitabine and nedaplatin for elderly patients with advanced non-small-cell lung cancer2011
- Author(s)
  Sugiyama T, Hirose T, Ohmori T et al
- Journal Title
  
  Oncology
  
  Volume: 81 Pages: 273-80
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22122886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Are levels of pro-gastrin-releasing peptide or neuron-specific enolase at relapse prognostic factors after relapse in patients with small -cell lung cancer?2011
- Author(s)
  Hirose T, Okuda K, Yamaoka T, Ishida K, Kusumoto S, Sugiyama T, Shirai T, Ohnshi T, Ohmori T, Adachi M
- Journal Title
  
  Lung Cancer
  
  Volume: 71(2) Issue: 2 Pages: 224-8
- DOI
  10.1016/j.lungcan.2010.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Phase II trial of amrubicin and carboplatin in patients with sensitive or refractory relapsed small-cell lung cancer.2011
- Author(s)
  Hirose T, Ohmori T et al
- Journal Title
  
  Lung Cancer
  
  Volume: 73 Pages: 345-50
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21277039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Are levels of pro-gastrin-releasing peptide or neuron-specific enolase at relapse prognostic factors after relapse in patients with small-cell lung cancer?2011
- Author(s)
  Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Lung Cancer
  
  Volume: 71(2) Pages: 224-228
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II study of S-1,a novel oral fluoropyrimidine,and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer2011
- Author(s)
  Oki Y, Hirose T, Yamaoka T, Kusumoto S, Shirai T, Sugiyama T, Okuda K, Nakashima M, Murata Y, Ohmori T, Adachi M
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 67(4) Issue: 4 Pages: 791-7
- DOI
  10.1007/s00280-010-1382-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Evaluation of the efficacy and safety of the combination of gemcitabine and nedaplatin for elderly patients with advanced non-small-cell lung cancer2011
- Author(s)
  Sugiyama T, Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Oncology
  
  Volume: 81(3-4) Pages: 273-280
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] The UGT1A1*28 genotype and the toxicity of low -dose irinotecan in patients with advanced lung cancer2010
- Author(s)
  Sugiyama T, Hirose T, Kusumoto S, Shirai T, Yamaoka T, Okuda K, Ohnishi T, Ohmori T, Adachi M
- Journal Title
  
  Oncol Res.
  
  Volume: 18(7) Pages: 337-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] Association of pharmacokinetics or pharmacogenomics with toxicity of erlotinib in patients with advanced NSCLC2014
- Author(s)
  廣瀬　敬
- Organizer
  第１２回日本臨床腫瘍学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590648
[Presentation] 非小細胞肺癌に対するエルロチニブの毒性に影響を与える薬物動態、薬理遺伝学的検討2014
- Author(s)
  廣瀬　敬
- Organizer
  第５４回日本呼吸器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590648
[Presentation] A novel c-MET inhibitor, tivantinib, shows an additive growth-inhibitory effect with erlotinib through enhanced degradation of c-MET protein via its recycling pathway2013
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  19^<th> International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  鹿児島(P-04)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Clinical benefit of 2nd EGFR-TKI retreatment on overall survival in patients with advanced non-small cell lung cancer2013
- Author(s)
  Masanao Nakashima, Takashi Hirose, Toshimitsu Yamaoka, Tohru Ohmori, et al
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台(P-1413)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 再発あるいは前治療無効小細胞肺癌に対するtopotecan、carboplatin併用第II相試験2013
- Author(s)
  慶瀬敬, 白井崇生, 杉山智英, 村田泰則, 大木康成, 楠本壮三郎, 中属賢尚, 奥田健太郎, 田村厚久, 大田健
- Organizer
  日本癌治療学会学術集会
- Place of Presentation
  京都
- Year and Date
  2013-10-24
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 非小細胞肺癌におけるエルロチニブとゾレドロン酸併用療法の有用性に関する後方視的解析2013
- Author(s)
  大木康成, 廣瀬敬, 白井崇生, 村田泰規, 杉山智英, 楠本壮二郎, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] The Characteristics of an acquired dual resistance to EGFR & MET inhibitors in non-small cell lung cancer, harbouring active mutation of EGFR2013
- Author(s)
  山岡利光, 市橋陽子, 村田泰規, 大木康成, 杉山智英, 石田博雄, 白井崇生, 廣瀬敬,中嶌賢尚, 奥田健太郎, 大西司, 大森亨
- Organizer
  米国癌学会 (AACR)
- Place of Presentation
  ワシントンDC
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] The characteristics of an acquired dual resistance to EGFR & MET inhibitors in non-small cell lung cancer, harboring active mutation of EGFR2013
- Author(s)
  Toshimitsu Yamaoka, Takashi Hirose, Tohru Ohmori et al
- Organizer
  #5648Annual Meeting 2013
- Place of Presentation
  American Association for Cancer Research Washington
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 再発あるいは前治療無効小細胞肺癌に対するtopotecan、carboplatin併用第II相試験2013
- Author(s)
  廣瀬敬, 白井崇生, 杉山智英, 村田泰則, 大木康成, 楠本壮二郎, 中嶌賢尚, 奥田健太郎, 大西司, 田村厚久, 大田健
- Organizer
  肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 非小細胞肺癌におけるエルロチニプとゾレドロン酸併用療法の有用性に関する後方視的解析2013
- Author(s)
  大木康成, 慶瀬敬, 白井崇生, 村田泰規, 杉山智英, 楠本壮三郎, 石田博雄, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 小細胞肺癌患者における末梢血中がん細胞数と予後の検討2013
- Author(s)
  白井崇生, 慶瀬敬, 村田泰規, 大木康成, 楠本壮三郎, 杉山智英, 石田博雄, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 再発あるいは前治療無効小細胞肺癌に対するtopotecan、carboplatin併用第II相試験2013
- Author(s)
  廣瀬敬, 白井崇生, 杉山智英, 村田泰則, 大木康成, 楠本壮二郎, 中嶌賢尚, 奥田健太郎, 田村厚久, 大田健
- Organizer
  日本癌治療学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 小細胞肺癌患者における末梢血中がん細胞数と予後の検討2013
- Author(s)
  白井崇生, 廣瀬敬, 村田泰規, 大木康成, 楠本壮二郎, 杉山智英, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] EGFR遺伝子変異陽性肺腺癌患者に対するゲフィチニブとゾレドロン酸併用療法の有用性に関する後方視的解析2012
- Author(s)
  大木康成, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page625)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] FGFR-TKIの再投与の有効性と安全性の検討2012
- Author(s)
  中嶌賢尚, 大木康成, 村田泰規, 石田孔子, 杉山智英, 石田博雄, 白井崇生, 山岡利光, 奥田健太郎, 大森亨, 大西司, 廣瀬敬
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] EGFR遺伝子変異陽性肺腺癌患者に対するゲフィチニブとゾレドロン酸併用療法の有用性に関する後方視的解析2012
- Author(s)
  大木康成, 廣瀬敬, 村田泰規, 杉山智英, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 糖尿病合併肺癌の現状について2012
- Author(s)
  楠本壮二郎, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page319)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine, carboplatin同時併用第II相試験2012
- Author(s)
  廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page326)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Carboplatin+Paclitaxel+Bevacizumabによる化学療法中にIII度房室ブロックをきたした肺腺癌症例2012
- Author(s)
  白井崇生, 廣瀬敬, 大木康成, 村田泰規, 楠本壮二郎, 杉山智英, 石田博雄, 中嶌賢尚, 奥田健太郎, 大西司, 足立満, 山岡利光, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 当院におけるCOPD合併切除不能非小細胞肺癌に関する検討2012
- Author(s)
  杉山智英, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page775)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] FGFR-TKIの再投与の有効性と安全性の検討.2012
- Author(s)
  中嶌賢尚, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page621)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine, carboplatin同時併用第II相試験2012
- Author(s)
  大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page579)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 当院におけるCOPD合併切除不能非小細胞肺癌に関する検討2012
- Author(s)
  杉山智英, 廣瀬敬, 大木康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 濱田健司
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Cancer Vaccination trial with novel multiple peptides in previously treated advanced non-small cell lung cancer.2012
- Author(s)
  Takashi Hirose, Hidehiro Noda, Tohru Ohmori et al
- Organizer
  Annual Meeting of American Society of Clinical Oncology 2012
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] SPC/TNFトランスジエニックマウスモデルにおけるEGFRチロシンキナーゼ阻害剤による肺組織のアポトーシス誘導機構の検討2012
- Author(s)
  山岡利光, 大木康成, 村田泰規, 杉山智英, 石田博雄, 白井崇生, 中属賢尚, 奥田健太郎, 大西司, 慶瀬敬, 大森亨
- Organizer
  日本呼吸器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  石田博雄, 大木康成, 村田泰規, 石田孔子, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 廣瀬敬
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACEを介したTNFによるEGFRのトランス活性化機序の検討2012
- Author(s)
  山岡利光, 村廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page323)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者進行非小細胞肺癌のnedaplatin+gemcitabine併用療法の有効性と安全性のレトロスペクティブ検討2012
- Author(s)
  山岡利光, 村田泰規, 大木康成, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 奥田健太郎, 大西司, 大森亨, 廣瀬敬, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 当院におけるCOPD合併肺癌手術例に関する検討2012
- Author(s)
  杉山智英, 廣瀬敬, 村田泰規, 大木康成, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 門倉光隆, 大森亨, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者小細胞肺癌に対する治療成績の検討2012
- Author(s)
  村田泰規, 廣瀬敬, 大木康成, 杉山智英, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Carboplatin+Paclitaxel+Bevacizumabによる化学療法中にIII度房室プロックをきたした肺腺癌症例2012
- Author(s)
  白井崇生, 慶瀬敬, 大木康成, 村田泰規, 楠本壮三郎, 杉山智英, 石田博雄, 中属賢尚, 奥田健太郎, 大西司, 足立満, 山岡利光, 大森亨
- Organizer
  日本肺癌学会
- Place of Presentation
  岡山
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] A novel c-MET inhibitor, tivantinib, shows an additive growth-inhibitory effect with erlotinib through enhanced degradation of c-MET protein via its recycling pathway2012
- Author(s)
  210. Tohru Ohmori, Tomoko Kanome, Toshimitsu Yamaoka, Takashi Hirose, Fumiaki Koizumi, Kazuto Nishio, Shiro Akinaga
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 標準治療不応進行非小細胞肺癌に対するペプチドワクチン療法(Cancer vaccination trial with novel mult iple peptides in previously treated advanced non-small-cell lung cancer (NSCLC))2012
- Author(s)
  慶瀬敬, 野田秀裕, 奥田健太郎, 阿部誠治, 大戸祐治, 杉山智英, 石田博雄, 白井崇生, 中属賢尚, 山岡利光, 大森亨, 吉田浩三, 中村祐輔
- Organizer
  日本癌学会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] Specific epidermal growth factor receptor autophosphorylation sites promote epithelial cell chemotaxis and restitution2012
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  103rd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine、carboplatin同時併用第II相試験2012
- Author(s)
  廣瀬敬, 村田泰規, 大木康成, 杉山智英, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] HSP 70 may cause EGFR-TKIs-resistance due to inhibit drug binding to EGFR in the cells that expressed mutant EGFR2012
- Author(s)
  Tohru Ohmori, Tsuyoki Kadofuku, Yoko Ichihashi, Toshimitsu Yamaoka, Takashi Hirose, Mitsuru Adachi, Nagahiro Saijo
- Organizer
  103rd Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Carboplatin+Paclitaxel+ Bevacizumabによる化学療法中にIII度房室ブロックをきたした肺腺2012
- Author(s)
  白井崇生, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (癌症例肺癌52巻3号Page359-360)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 糖尿病合併肺癌の現状について2012
- Author(s)
  楠本壮二郎, 大木康成, 村田泰規, 杉山智英, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 廣瀬敬, 大西司, 大森亨, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  石田博雄, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page586)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Cancer Vaccination trial with novel multiple peptides in previously treated advanced non-small cell lung cancer2012
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  Annual Meeting of American Society of Clinical Oncology
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者進行非小細胞肺癌のnedaplatin+gemcitabine併用療法の有効性と安全性のレトロスペクティブ検討2012
- Author(s)
  中嶌賢尚, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page264)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  石田博雄, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (日本癌治療学会誌47巻3号Page2134)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者小細胞肺癌に対する治療成績の検討2012
- Author(s)
  村田泰規, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page637)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進行肺大細胞神経内分泌癌と進展型小細胞肺癌に対する化学療法の有効性の比較2012
- Author(s)
  石田博雄, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page598)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  202. 石田博雄, 大木康成, 村田泰規, 石田孔子, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 廣瀬敬
- Organizer
  第50回日本癌治療学会総会
- Place of Presentation
  神奈川、横浜
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 手術を回避した高齢者気胸の検討2012
- Author(s)
  白井崇生, 慶瀬敬, 大木康成, 村田泰規, 杉山智英, 石田博雄, 中属賢尚, 大西司, 氷室直哉, 富田由里, 慶野素子, 片岡大輔, 野中誠, 門倉光隆
- Organizer
  日本呼吸器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] HSP 70 may cause EGFR-TKIs-resistance due to inhibit drug binding to EGFR in the cells that expressed mutant EGFR2012
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  Proceedings of American Association for Cancer Research, #1900
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine、carboplatin同時併用第II相試験2012
- Author(s)
  廣瀬敬, 大木康成, 村田泰規, 杉山智英, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] EGFR遺伝子変異陽性の肺腺癌患者に対する、ゲフィチニプとゾレドロン酸併用療法の有用性に関する後方視的解析2012
- Author(s)
  大木康成, 村田泰規, 杉山智英, 楠本壮三郎, 石田博雄, 白井崇生, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 慶瀬敬
- Organizer
  日本呼吸器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 当院におけるCOPD合併肺癌手術例に関する検討2012
- Author(s)
  杉山智英, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page326)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 当院におけるCOPD合併肺癌手術例に関する検討2011
- Author(s)
  杉山智英, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page516)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] HSP70 may cause EGFR-TKIs-resistance due to inhibit drug binding to EGFR in the cell that expressed mutant EGFR2011
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋(English oral session E-1017)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 超高齢者進行非小細胞肺癌の治療の有用性と安全性について2011
- Author(s)
  奥田健太郎, 廣瀬敬, 山岡利光, 大森亨, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page294)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] HSP70 specifically binds to 15 bp deletion mutant EGFR and modulates sensitivity to EGFR-TKI2011
- Author(s)
  Tsuyoki Kadofuku, Toshimitsu Yamaoka, Takashi Hirose, Tohru Ohmori, et al
- Place of Presentation
  Orland FL, USA(Proceedings of American Association for Cancer Research, Vol. 52 699)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者進行非小細胞肺癌に対するnedaplatin +gemcitabine併用療法の有効性と安全性の検討2011
- Author(s)
  中嶌賢尚, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page486)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] EGFR-TKI耐性細胞に対するARQ197のMet阻害機構2011
- Author(s)
  大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  第15回がん分子標的治療研究会総会
- Place of Presentation
  東京(ワークショップW6-4)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] IV期非小細胞肺がんにおける末梢血中がん細胞数(CTC)と抗がん剤治療の効果と予後との関連性2011
- Author(s)
  廣瀬敬
- Organizer
  日本肺癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 糖尿病合併肺癌の現状について2011
- Author(s)
  楠本壮二郎, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page495)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] IV期非小細胞肺がんにおける末梢血中がん細胞数(CTC)と抗がん剤治療の効果と予後との関連性2011
- Author(s)
  廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page421)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 再発あるいは前治療無効小細胞肺癌(SCLC)に対するamrubicin, carboplatin併用第II相試験2011
- Author(s)
  廣瀬敬, 山岡利光, 大森亨, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page295)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 発熱性好中球減少症におけるプロカルシトニンの有用性の検討2011
- Author(s)
  杉山智英, 廣瀬敬, 山岡利光, 大森亨, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page162)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACE/EGFR-リガンドを介したTNFによるEGFRのトランス活性化の機序検討(TNF transactivates phospho-tyrosine 1068 of EGFR through TACE/EGFR-ligand dependent mechanism)2011
- Author(s)
  山岡利光, 大木康成, 楠本壮三郎, 杉山智英, 白井崇生, 中属賢尚, 奥田健太郎, 慶瀬敬, 大森亨, 大西司, 足立満
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] TNF transactivates phospho-tyrosine 1068 of EGFR through TACE/EGFR-ligand dependent mechanism2011
- Author(s)
  Toshimitsu Yamaoka, Takashi Hirose, Tohru Ohmori, et al
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋(P-2051)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と肺癌細胞におけるTNFによるEGFRトランス活性化に寄与するリガンドの同定とアポトーシス制御機構2011
- Author(s)
  山岡利光, 大森亨, 廣瀬敬, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page159)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進行非小細胞肺癌の生存期間が延長しているのはなぜか?2010
- Author(s)
  白井崇生, 慶瀬敬, 楠本壮三郎, 杉山智英, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 足立満
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 非小細胞肺癌に対するエルロチニブの毒性に影響を与える薬物動態、薬理遺伝学的検討
- Author(s)
  廣瀬敬, 藤田健一, 楠本壮二郎, 白井崇生, 村田泰則, 大木康成, 杉山智英, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 佐々木康綱, 田村厚久, 大田健
- Organizer
  第54回日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-23590648
[Presentation] ssociation of pharmacokinetics or pharmacogenomics with toxicity of erlotinib in patients with advanced NSCLC
- Author(s)
  Takashi Hirose, Ken-ichi Fujita, Sojiro Kusumoto, Takao Shirai, Tomohide Sugiyama, Masanao Nakashima, Tohru Ohmori, Yasutsuna Sasaki, Atsuhisa Tamura , Ken Ohta
- Organizer
  第12回臨床腫瘍学会
- Data Source
  KAKENHI-PROJECT-23590648

1. YAMAOKA Toshimitsu (40384359)

# of Collaborated Projects: 3 results

# of Collaborated Products: 76 results
2. OHMORI Tohru (10276529)

# of Collaborated Projects: 3 results

# of Collaborated Products: 81 results
3. ADACHI Mitsuru (10095870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. SIRAI Takao (90384362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
5. KADOKURA Mitsutaka (60214417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 藤田健一 (60281820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 佐々木康綱 (20235279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Hirose Takashi 廣瀬 敬

HIROSE Takashi 慶瀬 敬

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Elucidation of trans-activation mechanism from TRAIL receptor to EGFR

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Association of pharmacokinetics or pharmacogenomics with toxicity of erlotinib in patients with advanced non-small cell lung cancerPrincipal Investigator

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The role of ADAM17 in squamous cell lung cancer

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[Journal Article] 進行再発非小細胞肺癌に対するセカンドライン化学療法の検討2012

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[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer.2012

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[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer.2012

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[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer2012

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[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease2012

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[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease2012

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[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer2012

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[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease.2012

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[Journal Article] Phase II trial of the combination of carboplatin and irinotecan in elderly patients with small-cell lung cancer.2011

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[Journal Article] Myelosuppression induced by concurrent chemoradiotherapy as a prognostic factor for patients with locally advanced non-small cell lung cancer2011

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[Journal Article] Phase II trial of amrubicin and carboplatin in patients with sensitive or refractory relapsed small-cell lung cancer2011

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[Journal Article] Phase II study of S-1, a novel oral fluoropyrimidine, and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer.2011

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[Journal Article] Phase II trial of amrubicin and carboplatin in patients with sensitive or refractory relapsed small -cell lung cancer2011

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Hirose Takashi 廣瀬敬

HIROSE Takashi 慶瀬敬