Takagi Yasushi 高木康志

… Alternative Names

高木康志タカギヤスシ

TAKAGI Yasushi 高木康志

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Researcher Number	40312227
Other IDs
External Links
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 徳島大学, 大学院医歯薬学研究部(医学域), 教授 2018: 徳島大学, 大学院医歯薬学研究部(医学域), 教授 2017: 徳島大学 2016 – 2017: 京都大学, 医学研究科, 准教授 2013 – 2016: 京都大学, 医学(系)研究科(研究院), 准教授 … More 2015: 京都大学, 大学院医学研究科, 准教授 2014: 京都大学, 医学研究科, 准教授 2011 – 2012: 京都大学, 医学研究科, 准教授 2010: Kyoto University, 医学研究科, 講師 2009 – 2010: Kyoto University, 医学研究科, 非常勤講師 2007 – 2008: Kyoto University, Graduate School of Medicine, Lecturer 2007: Kyoto University, 医学研究科, 助教 2003 – 2006: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Neurosurgery / Epidemiology and preventive medicine
Keywords	Principal Investigator 脳梗塞 / 神経幹細胞 / 胚性幹細胞 / 脳血管障害学 / 移植治療 / 移植 / 骨髄間質細胞 / 再生医療 / ES細胞 / 脳虚血 … More / CitH3 / KRAS遺伝子 / 血管新生 / PAD4 / 脳動静脈奇形 / 炎症性変化 / 脳出血 / 血管増生 / NETｓ形成 / KRAS変異 / Brain AVM / primate / regenerative therapy / brain ischemia / ES cell / 霊長類 / 神経再生治療 / 神経幹細胞移植 / iPS細胞 / 脳梗塞モデル / 霊長類ES細胞 / 免疫組織 / SDIA … More Except Principal Investigator MAPK / 脳梗塞 / もやもや病 / 脳動脈瘤 / Inflammasome / 歯周病菌 / 脳動脈瘤破裂 / sirtuin / ischemic tolerance / cerebral ischemia / STAT / 脳虚血 / 脳血管障害 / 脳卒中 / 遺伝子 / NETosis / クモ膜下出血 / 重症歯周病 / Matrix metalloproteage / 破裂性脳動脈瘤 / NLRP3 inflammasome / くも膜下出血 / Sirtuin / NLRP3　inflammasome / ERa / NLRP3 / 破裂性脳血管病 / ERα / 歯周病 / exosome / periodontal bacteria / periodontal disease / intracranial aneurysms / SAH / quality of life / moyamoya disease / 認知機能 / 社会的アウトカム / 生活の質 / 脳血管障害学 / RNF213 / 脳神経疾患 / 神経細胞死 / Ischemic tolerance / Cerebral ischemia / MARK / 虚血耐性 / 医歯薬学 / 衛生学 / 社会医学 / 予防医学 / 分子遺伝疫学 / 分子イメージング / 血管新生 / バソヒビン / 血管新生調節因子 / プラーク内出血 / 頚動脈狭窄 / 不安定プラーク / 動脈硬化 / 頭蓋内主幹動脈 / 脳神経外科学 / 遺伝子発現 Less

脳血管障害に影響を及ぼす特定歯周病菌の同定とその制御法の検討
- Principal Investigator
  
  兼松康久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokushima
脳動静脈奇形における血管内皮のKRAS変異とPAD4活性化の関係Principal Investigator
- Principal Investigator
  
  高木康志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokushima
Effects of exosomes of periodontal lesions on ruptured cerebral aneurysms
- Principal Investigator
  
  SHIMADA Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokushima
Role of inflammasome activation and sirtuins in cerebral aneurysm rupture
- Principal Investigator
  
  KANEMATSU Yasuhisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokushima
Identification of modifiers of moyamoya disease causing gene RNF213 and development of in vitro and in vivo models of the disease
- Principal Investigator
  
  Miyamoto Susumu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyoto University
Cohort study of pediatric moyamoya disease focusing on factors associated with social outcome and quality of life after pediatric patients reach adulthood
- Principal Investigator
  
  Takeshi Funaki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyoto University
Molecular pathology of moyamoyta disease and its translational research toward prevention and drug development
- Principal Investigator
  
  KOIZUMI Akio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Kyoto University
Transplantation of iPS cell-derived neuronal stem cells into ischemic brainPrincipal Investigator
- Principal Investigator
  
  Takagi Yasushi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyoto University
The molecular mechanism of major intracranial arterial stenosis
- Principal Investigator
  
  MIYAMOTO Susumu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
Expression and role of the novel angiogenic regulatory factor Vasohibin-1 in the carotid atherosclerotic plaques
- Principal Investigator
  
  YOSHIDA Kazumichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
Stroke therapy using embryonic stem cells and bone marrow stromal cell-derived neuralstem cellsPrincipal Investigator
- Principal Investigator
  
  TAKAGI Yasushi
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
Transplantation of primate embryonic stem cell-derived neural stem cell against brain ischemiaPrincipal Investigator
- Principal Investigator
  
  TAKAGI Yasushi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
Involvement of MAPK cascade in ischemic neuronal damage
- Principal Investigator
  
  NOZAKI Kazuhiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
実験的脳動脈瘤における遺伝子発現
- Principal Investigator
  
  NOZAKI Kazuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
霊長類ES細胞由来神経細胞を利用した脳梗塞の治療Principal Investigator
- Principal Investigator
  
  高木康志
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
Basic research for cerebral ischemia therapy based on ischemic tolerance
- Principal Investigator
  
  NOZAKI Kazuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  KYOTO UNIVERSITY

[Book] Moyamoya Disease Explored Through RNF213: Genetics, Molecular Pathology, and Clinical Sciences (Current Topics in Environmental Health and Preventive Medicine)2017
- Author(s)
  Mineharu Y, Takagi Y, Miyamoto S
- Publisher
  Springer
- ISBN
  9789811027109
- Data Source
  KAKENHI-PROJECT-16H05437
[Journal Article] Evaluation of Serial Intra-Arterial Indocyanine Green Videoangiography in the Surgical Treatment of Cranial and Craniocervical Junction Arteriovenous Fistulae: A Case Series2023
- Author(s)
  Yamaguchi Izumi、Kanematsu Yasuhisa、Shimada Kenji、Yamamoto Nobuaki、Korai Masaaki、Miyake Kazuhisa、Miyamoto Takeshi、Sogabe Shu、Shikata Eiji、Ishihara Manabu、Yamamoto Yuki、Kuroda Kazutaka、Takagi Yasushi
- Journal Title
  
  Operative Neurosurgery
  
  Volume: 25 Pages: 292-300
- DOI
  10.1227/ons.0000000000000796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-23K08500
[Journal Article] Activation of the NLRP3/IL-1β/MMP-9 pathway and intracranial aneurysm rupture associated with the depletion of ERα and Sirt1 in oophorectomized rats2023
- Author(s)
  Yamaguchi Tadashi、Miyamoto Takeshi、Shikata Eiji、Yamaguchi Izumi、Shimada Kenji、Yagi Kenji、Tada Yoshiteru、Korai Masaaki、Kitazato Keiko T.、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: 138 Issue: 1 Pages: 191-198
- DOI
  10.3171/2022.4.jns212945
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-20K09391, KAKENHI-PROJECT-20K17933
[Journal Article] Experience of using coronary perfusion balloon catheter for acute middle cerebral artery occlusion2023
- Author(s)
  Sogabe Shu、Haboshi Tatsuya、Yamaguchi Izumi、Korai Masaaki、Yamamoto Nobuaki、Shimada Kenji、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Surgical Neurology International
  
  Volume: 14 Pages: 365-365
- DOI
  10.25259/sni_608_2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-23K08500
[Journal Article] Efficacy of Utilizing Both 3-Dimensional Multimodal Fusion Image and Intra-Arterial Indocyanine Green Videoangiography in Cerebral Arteriovenous Malformation Surgery2023
- Author(s)
  Shimada Kenji、Miyake Kazuhisa、Yamaguchi Izumi、Sogabe Shu、Korai Masaaki、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  World Neurosurgery
  
  Volume: 169 Pages: e260-e269
- DOI
  10.1016/j.wneu.2022.10.121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-20K09326
[Journal Article] Squamous cell carcinoma invading peripheral cerebral blood vessels and causing repeated cerebral hemorrhage : A case report2023
- Author(s)
  Koyama Hiroshi、Nakajima Kohei、Okita Shinya、Taniguchi Hidekazu、Hagino Hirotaka、Bando Yoshimi、Uehara Hisanori、Takagi Yasushi
- Journal Title
  
  J. Med. Invest.
  
  Volume: 70 Issue: 1.2 Pages: 276-280
- DOI
  10.2152/jmi.70.276
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259
[Journal Article] Differences in amyloid-β and tau/p-tau deposition in blood-injected mouse brains using micro-syringe to mimic traumatic brain microhemorrhages2023
- Author(s)
  Kagusa Hiroshi、Yamaguchi Izumi、Shono Kenji、Mizobuchi Yoshifumi、Shikata Eiji、Matsuda Taku、Miyamoto Takeshi、Hara Keijiro、Kitazato Keiko T.、Uto Yoshihiro、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Chemical Neuroanatomy
  
  Volume: 130 Pages: 102258-102258
- DOI
  10.1016/j.jchemneu.2023.102258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16662, KAKENHI-PROJECT-22K09259
[Journal Article] Transarterial embolization for convexity dural arteriovenous fistula with or without pial arterial supply: A report of four patients2022
- Author(s)
  Korai Masaaki、Enomoto Noriya、Satoh Koichi、Matsubara Shunji、Kanematsu Yasuhisa、Yamaguchi Tadashi、Hanaoka Mami、Niki Hitoshi、Matsuzaki Kazuhito、Bando Koji、Hagino Hirotaka、Takagi Yasushi
- Journal Title
  
  Surgical Neurology International
  
  Volume: 13 Pages: 340-340
- DOI
  10.25259/sni_215_2022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259
[Journal Article] Single-session hematoma removal and transcortical venous approach for coil embolization of an isolated transverse-sigmoid sinus dural arteriovenous fistula in a hybrid operating room: illustrative case2022
- Author(s)
  Yamaguchi Izumi、Kanematsu Yasuhisa、Shimada Kenji、Yamamoto Nobuaki、Miyake Kazuhisa、Miyamoto Takeshi、Sogabe Shu、Shikata Eiji、Ishihara Manabu、Yamamoto Yuki、Kuroda Kazutaka、Takagi Yasushi
- Journal Title
  
  Journal of Neurosurgery: Case Lessons
  
  Volume: 3 Issue: 21
- DOI
  10.3171/case2267
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-20K09326
[Journal Article] An imbalance between RAGE/MR/HMGB1 and ATP1α3 is associated with inflammatory changes in rat brain harboring cerebral aneurysms prone to rupture2022
- Author(s)
  Shikata Eiji、Miyamoto Takeshi、Yamaguchi Tadashi、Yamaguchi Izumi、Kagusa Hiroshi、Gotoh Daiki、Shimada Kenji、Tada Yoshiteru、Yagi Kenji、Kitazato Keiko T.、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 19 Issue: 1
- DOI
  10.1186/s12974-022-02526-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-20K09391
[Journal Article] Efficacy of intraarterial indocyanine green videoangiography in surgery for arteriovenous fistula at the craniocervical junction in a hybrid operating room: illustrative cases2022
- Author(s)
  Shimada Kenji、Yamaguchi Izumi、Miyamoto Takeshi、Sogabe Shu、Miyake Kazuhisa、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Neurosurgery: Case Lessons
  
  Volume: 3 Issue: 23
- DOI
  10.3171/case22100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-20K09326
[Journal Article] Role of post-ischemic phase-dependent modulation of anti-inflammatory M2-type macrophages against rat brain damage2022
- Author(s)
  Kurashiki Yoshitaka、Kagusa Hiroshi、Yagi Kenji、Kinouchi Tomoya、Sumiyoshi Manabu、Miyamoto Takeshi、Shimada Kenji、Kitazato Keiko T、Uto Yoshihiro、Takagi Yasushi
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 43 Issue: 4 Pages: 531-541
- DOI
  10.1177/0271678x221147090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09326
[Journal Article] Elevated Urinary Titin and its Associated Clinical Outcomes after Acute Stroke2021
- Author(s)
  Ishihara Manabu、Nakanishi Nobuto、Tsutsumi Rie、Hara Kanako、Machida Kyoka、Yamamoto Nobuaki、Kanematsu Yasuhisa、Sakaue Hiroshi、Oto Jun、Takagi Yasushi
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 30 Issue: 3 Pages: 105561-105561
- DOI
  10.1016/j.jstrokecerebrovasdis.2020.105561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09391, KAKENHI-PROJECT-19H04055
[Journal Article] Disequilibrium of plasma protease/anti-protease due to severe periodontal disease contributes to human subarachnoid hemorrhage2020
- Author(s)
  Yoshioka S, Miyamoto T, Satomi J, Tada Y, Yagi K, Shimada K, Naruishi K, Shikata E, Yamaguchi I, Yamaguchi1 T, Korai M, Okayama Y, Harada M, Kitazato K, Kanematsu Y, Nagahiro S, Takagi Y
- Journal Title
  
  Neurosurgery Open
  
  Volume: 1 Issue: 3 Pages: 1-9
- DOI
  10.1093/neuopn/okaa007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10131, KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-19K24013
[Journal Article] Factors associated with DWI-ASPECTS score in patients with acute ischemic stroke due to cerebral large vessel occlusion2020
- Author(s)
  Yamamoto Nobuaki、Izumi Yuishin、Yamamoto Yuki、Kuroda Kazutaka、Yamaguchi Izumi、Sogabe Shu、Miyamoto Takeshi、Shimada Kenji、Kanematsu Yasuhisa、Morigaki Ryoma、Takagi Yasushi
- Journal Title
  
  Clinical Neurology and Neurosurgery
  
  Volume: 199 Pages: 106316-106316
- DOI
  10.1016/j.clineuro.2020.106316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-20K09391
[Journal Article] High White Blood Cell Count Is a Risk Factor for Contrast-Induced Nephropathy following Mechanical Thrombectomy for Acute Ischemic Stroke2020
- Author(s)
  Yamamoto Yuki、Yamamoto Nobuaki、Kanematsu Yasuhisa、Kuroda Kazutaka、Yamaguchi Izumi、Miyamoto Takeshi、Sogabe Shu、Shimada Kenji、Takagi Yasushi、Izumi Yuishin
- Journal Title
  
  Cerebrovascular Diseases Extra
  
  Volume: 10 Issue: 2 Pages: 59-65
- DOI
  10.1159/000507918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09391
[Journal Article] Cerebral Venous Thrombosis: An Unexpected Complication with Cerebrospinal Fluid Leaks after a Fall in a Patient with Spinocerebellar Ataxia Type 62020
- Author(s)
  Yamamoto Yuki、Yamamoto Nobuaki、Fujita Koji、Fukumoto Tatsuya、Murakami Nagahisa、Mure Hideo、Kanematsu Yasuhisa、Takagi Yasushi、Izumi Yuishin
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 14 Pages: 1749-1753
- DOI
  10.2169/internalmedicine.4388-20
- NAID
  130007873318
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-07-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09391
[Journal Article] Efficacy of intraarterial superselective indocyanine green videoangiography in cerebral arteriovenous malformation surgery in a hybrid operating room2020
- Author(s)
  Shimada Kenji、Yamaguchi Tadashi、Miyamoto Takeshi、Sogabe Shu、Korai Masaaki、Okazaki Toshiyuki、Kanematsu Yasuhisa、Satomi Junichiro、Nagahiro Shinji、Takagi Yasushi
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: - Issue: 5 Pages: 1-9
- DOI
  10.3171/2020.3.jns20319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-20K09391, KAKENHI-PROJECT-18K16562
[Journal Article] Basic research and surgical techniques for brain arteriovenous malformations2020
- Author(s)
  Takagi Yasushi、Kanematsu Yasuhisa、Mizobuchi Yoshifumi、Mure Hideo、Shimada Kenji、Tada Yoshiteru、Morigaki Ryoma、Sogabe Shu、Fujihara Toshitaka、Miyamoto Takeshi、Miyake Kazuhisa
- Journal Title
  
  J. Med. Invest.
  
  Volume: 67 Issue: 3.4 Pages: 222-228
- DOI
  10.2152/jmi.67.222
- NAID
  130007936872
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-20K09391
[Journal Article] Restoration of periventricular vasculature after direct bypass for moyamoya disease: intra-individual comparison2019
- Author(s)
  Miyakoshi Akinori、Funaki Takeshi、Takahashi Jun C、Takagi Yasushi、Kikuchi Takayuki、Yoshida Kazumichi、Kataoka Hiroharu、Mineharu Yohei、Okawa Masakazu、Yamao Yukihiro、Fushimi Yasutaka、Okada Tomohisa、Togashi Kaori、Miyamoto Susumu
- Journal Title
  
  Acta Neurochirurgica
  
  Volume: Epub aheda of print Issue: 5 Pages: 947-954
- DOI
  10.1007/s00701-019-03866-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-18K07711
[Journal Article] Dysregulation of RNF213 promotes cerebral hypoperfusion2018
- Author(s)
  Morimoto T, Enmi J, Hattori Y, Iguchi S, Saito S, Harada K, Okuda H, Mineharu Y, Takagi Y, Youssefian S, Iida H, Miyamoto S, Ihara M, Kobayashi H, Koizumi A.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 3607-3607
- DOI
  10.1038/s41598-018-22064-8
- NAID
  120006510289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-15K19243, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19963
[Journal Article] Significant association of RNF213 p.R4810K, a moyamoya susceptibility variant, with coronary artery disease2017
- Author(s)
  Morimoto T, Mineharu Y, Ono K, Nakatochi M, Ichihara S, Kabata R, Takagi Y, Cao Y, Zhao L, Kobayashi H, Harada K. H, Takenaka K, Funaki T, Yokota M, Matsubara T, Yamamoto K, Izawa H, Kimura T, Miyamoto S, Koizumi A
- Journal Title
  
  PLoS ONE
  
  Volume: 12 Issue: 4 Pages: e0175649-e0175649
- DOI
  10.1371/journal.pone.0175649
- NAID
  120006534994
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05250, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-25293308, KAKENHI-PROJECT-26293149, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-16K09460, KAKENHI-PROJECT-15K19963, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17J04066, KAKENHI-PROJECT-15K15236, KAKENHI-PROJECT-15K19243
[Journal Article] Rapid contralateral progression of focal cerebral arteriopathy distinguished from RNF213-related moyamoya disease and fibromuscular dysplasia2017
- Author(s)
  Araki Yoshio、Takagi Yasushi、Mineharu Yohei、Kobayashi Hatasu、Miyamoto Susumu、Wakabayashi Toshihiko
- Journal Title
  
  Child's Nervous System
  
  Volume: 33 Issue: 8 Pages: 1405-1409
- DOI
  10.1007/s00381-017-3451-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19963, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19243
[Journal Article] RNF213 p.R4810K Variant and Intracranial Arterial Stenosis or Occlusion in Relatives of Patients with Moyamoya Disease2017
- Author(s)
  Matsuda Yoshiko、Mineharu Yohei、Kimura Mitsuru、Takagi Yasushi、Kobayashi Hatasu、Hitomi Toshiaki、Harada Kouji H.、Uchihashi Yoshito、Funaki Takeshi、Miyamoto Susumu、Koizumi Akio
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 26 Issue: 8 Pages: 1841-1847
- DOI
  10.1016/j.jstrokecerebrovasdis.2017.04.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19963, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19243
[Journal Article] Reversible striatal hypermetabolism in chorea associated with moyamoya disease: a report of two cases2016
- Author(s)
  Sugita Y, Funaki T, Takahashi JC, Takagi Y, Fushimi Y, Kikuchi T, Yoshida K, Hatano T, Sasaki N, Miyamoto S.
- Journal Title
  
  Childs Nerv Syst
  
  Volume: 32(11) Issue: 11 Pages: 2243-2247
- DOI
  10.1007/s00381-016-3111-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-25293308
[Journal Article] Factors Predicting the Effects of Hybrid Assistive Limb Robot Suit during the Acute Phase of Central Nervous System Injury2016
- Author(s)
  1.Hideo Chihara, Yasushi Takagi, Kazunari Nishino, Kazumichi Yoshida, Yoshiki Arakawa, Takayuki Kikuchi, Yohei Takenobu, Susumu Miyamoto
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 56 Issue: 1 Pages: 33-37
- DOI
  10.2176/nmc.oa.2015-0178
- NAID
  130005119820
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462254, KAKENHI-PROJECT-25293308
[Journal Article] Histopathological Characteristics of Distal Middle Cerebral Artery in Adult and Pediatric Patients with Moyamoya Disease2016
- Author(s)
  Takagi Y, Hermanto Y, Takahashi JC, Funaki T, Kikuchi T, Mineharu Y, Yoshida K, Miyamoto S
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 56 Issue: 6 Pages: 345-349
- DOI
  10.2176/nmc.oa.2016-0031
- NAID
  130005157729
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-25293308
[Journal Article] Histopathological Features of Brain Arteriovenous Malformations in Japanese Patients2016
- Author(s)
  Hermanto Y, Takagi Y, Yoshida K, Ishii A, Kikuchi T, Funaki T, Mineharu Y, Miyamoto S.
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 56 Issue: 6 Pages: 340-344
- DOI
  10.2176/nmc.oa.2016-0032
- NAID
  130005157730
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-25293308
[Journal Article] Significant Association of the RNF213 p.R4810K Polymorphism with Quasi-Moyamoya Disease2016
- Author(s)
  Morimoto T, Mineharu Y, Kobayashi H, Harada KH, Funaki T, Takagi Y, Sakai N, Miyamoto S, Koizumi A
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 25(11) Issue: 11 Pages: 2632-2636
- DOI
  10.1016/j.jstrokecerebrovasdis.2016.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-25293308, KAKENHI-PROJECT-15K19243, KAKENHI-PROJECT-15K19963
[Journal Article] Voxel Based Analysis of Surgical Revascularization for Moyamoya Disease: Pre- and Postoperative SPECT Studies.2016
- Author(s)
  Fushimi Y, Okada T, Takagi Y, Funaki T, Takahashi JC, Miyamoto S, Togashi K.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 2 Pages: e0148925-e0148925
- DOI
  10.1371/journal.pone.0148925
- NAID
  120005763395
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461819, KAKENHI-PLANNED-25120002, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-25293308
[Journal Article] Unstable moyamoya disease: clinical features and impact on perioperative ischemic complications.2015
- Author(s)
  Funaki T, Takahashi JC, Takagi Y, Kikuchi T, Yoshida K, Mitsuhara T, Kataoka H, Okada T, Fushimi Y, Miyamoto S.
- Journal Title
  
  J Neurosurg
  
  Volume: 122 Issue: 2 Pages: 400-7
- DOI
  10.3171/2014.10.jns14231
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390343, KAKENHI-PROJECT-25861273
[Journal Article] Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo.2015
- Author(s)
  Kobayashi H, Matsuda Y, Hitomi T, Okuda H, Shioi H, Matsuda T, Imai H, Sone M, Taura D, Harada KH, Habu T, Takagi Y, Miyamoto S, Koizumi A.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 30;4(7) Issue: 7
- DOI
  10.1161/jaha.115.002146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07044, KAKENHI-PROJECT-26460801, KAKENHI-PROJECT-15K19243, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-24300161
[Journal Article] Immunohistochemical Analysis of Sox17 Associated Pathway in Brain Arteriovenous Malformations.2015
- Author(s)
  Hermanto Y, Takagi Y, Ishii A, Yoshida K, Kikuchi T, Funaki T, Mineharu Y, Miyamoto S.
- Journal Title
  
  World Neurosurg
  
  Volume: 24 Pages: 1506-1512
- DOI
  10.1016/j.wneu.2015.10.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19963, KAKENHI-PROJECT-25293308
[Journal Article] Cognitive function of patients with adult moyamoya disease.2014
- Author(s)
  Araki Y, Takagi Y, Ueda K, Ubukata S, Ishida J, Funaki T, Kikuchi T, Takahashi JC, Murai T, Miyamoto S.
- Journal Title
  
  J Stroke Cerebrovasc Dis.
  
  Volume: 23 Issue: 7 Pages: 1789-94
- DOI
  10.1016/j.jstrokecerebrovasdis.2014.04.032
- NAID
  120005468377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390343, KAKENHI-PROJECT-24791496
[Journal Article] Incidence of late cerebrovascular events after direct bypass among children with moyamoya disease: a descriptive longitudinal study at a single center.2014
- Author(s)
  Funaki T, Takahashi JC, Takagi Y, Yoshida K, Araki Y, Kikuchi T, Kataoka H, Iihara K, Sano N, Miyamoto S.
- Journal Title
  
  Acta Neurochir (Wien).
  
  Volume: 156 Issue: 3 Pages: 551-9
- DOI
  10.1007/s00701-013-1975-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390343
[Journal Article] Exacerbation of intracranial aneurysm and aortic dissection in hypertensive rat treated with the prostaglandin F-receptor antagonist AS604872.2014
- Author(s)
  Fukuda M, Aoki T, Manabe T, Maekawa A, Shirakawa T, Kataoka H, Takagi Y, Miyamoto S, Narumiya S.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 126 Pages: 230-42
- NAID
  130004700281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390343
[Journal Article] Impact of posterior cerebral artery involvement on long-term clinical and social outcome of pediatric moyamoya disease.2013
- Author(s)
  Funaki T, Takahashi JC, Takagi Y, Yoshida K, Araki Y, Kikuchi T, Kataoka H, Iihara K, Miyamoto S.
- Journal Title
  
  J Neurosurg Pediatr.
  
  Volume: 12(6) Issue: 6 Pages: 626-32
- DOI
  10.3171/2013.9.peds13111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390343
[Journal Article] Notch signaling regulates nucleocytoplasmic Olig2 translocation in reactive astrocytes differentiation after ischemic stroke2013
- Author(s)
  Marumo T, Takagi Y, Muraki K, Hashimoto N, Miyamoto S, Tanigaki K.
- Journal Title
  
  Neurosci Res
  
  Volume: 75(3) Issue: 3 Pages: 204-9
- DOI
  10.1016/j.neures.2013.01.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790350, KAKENHI-PROJECT-24659143, KAKENHI-PROJECT-25293308
[Journal Article] The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431)2013
- Author(s)
  Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 439(4) Issue: 4 Pages: 419-426
- DOI
  10.1016/j.bbrc.2013.08.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PROJECT-23501267, KAKENHI-PROJECT-23590741, KAKENHI-PROJECT-24390343, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-25840024, KAKENHI-PROJECT-25893104
[Journal Article] Rapid Progression of Unilateral Moyamoya Disease in a Patient with a Family History and an RNF213 Risk Variant2013
- Author(s)
  Mineharu Y, Hitomi T, Kobayashi H Koizumi A. et al.
- Journal Title
  
  Cerebrovasc Dis
  
  Volume: 36(2) Issue: 2 Pages: 155-7
- DOI
  10.1159/000352065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590741, KAKENHI-PROJECT-24390343, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-25893104
[Journal Article] Transplantation of telencephalic neural progenitors induced from embryonic stem cells into subacute phase of focal cerebral ischemia2012
- Author(s)
  Fujimoto M, Hayashi H, Takagi Y, Hayase M, Marumo T, Gomi M, Nishimura M, Kataoka H, Takahashi J, Hashimoto N, Nozaki K, Miyamoto S.
- Journal Title
  
  Lab Invest
  
  Volume: 92(4) Issue: 4 Pages: 522-31
- DOI
  10.1038/labinvest.2012.1
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Functional recovery of the murine brain ischemia model using human induced pluripotent stem cell-derived telencephalic progenitors2012
- Author(s)
  Gomi M, Takagi Y, Morizane A, Doi D, Nishimura M, Miyamoto S, Takahashi J.
- Journal Title
  
  Brain Res
  
  Volume: 12 Pages: 52-60
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Committed neural progenitor cells derived from genetically modified bone marrow stromal cells ameliorate deficits in a rat model of stroke2009
- Author(s)
  Hayase M, Kitada M, Wakao S, Itokazu Y, Nozaki K, Hashimoto N, Takagi Y, Dezawa M.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 29(8) Pages: 1409-20
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] RBP-J promotes neuronal differentiation and inhibits oligodendroglial development in adult neurogenesis.2009
- Author(s)
  Fujimoto M, Takagi Y, Muraki K, Nozaki K, Yamamoto N, Tsuji M, Hashimoto N, Honjo T, Tanigaki K.
- Journal Title
  
  Dev Biol. 15;332(2)
  
  Pages: 339-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Attenuation of neuronal degeneration in thioredoxin-1 overexpressing mice after mild focal ischemia2009
- Author(s)
  Zhou F, Gomi M, Fujimoto M, Hayase M, Marumo T, Masutani H, Yodoi J, Hashimoto N, Nozaki K, Takagi Y.
- Journal Title
  
  Brain Res
  
  Volume: 26 Pages: 62-70
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Attenuation of neuronal degeneration in thioredoxin-1 overexpressing mice after mild focal ischemia.2009
- Author(s)
  Zhou F, Gomi M, Fujimoto M, Hayase M, Marumo T, Masutani H, Yodoi J, Hashimoto N, Nozaki K, Takagi Y.
- Journal Title
  
  Brain Res. 26;1272
  
  Pages: 62-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Committed neural progenitor cells derived from genetically modified bone marrow stromal cells ameliorate deficits in a rat model of stroke.2009
- Author(s)
  Hayase M, Kitada M, Wakao S, Itokazu Y, Nozaki K, Hashimoto N, Takagi Y, Dezawa M.
- Journal Title
  
  J Cereb Blood Flow Metab. 29(8)
  
  Pages: 1409-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] RBP-J promotes neuronal differentiation and inhibits oligodendroglial development in adult neurogenesis2009
- Author(s)
  Fujimoto M, Takagi Y, Muraki K, NozakiK, Yamamoto N, Tsuji M, Hashimoto N, Honjo T, Tanigaki K.
- Journal Title
  
  Dev Biol
  
  Volume: 332(2) Pages: 339-50
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Tissue inhibitor of metalloproteinases protect blood-brain barrier disruption in focal cerebral ischemia.2008
- Author(s)
  Fujimoto M, Takagi Y, Aoki T, Hayase M, Marumo T, Gomi M, Nishimura M, Kataoka H, Hashimoto N, Nozaki K.
- Journal Title
  
  J Cereb Blood Flow Metab. 28(10)
  
  Pages: 1674-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Targeted disruption of Hsp110/105 gene protects against ischemic stress2008
- Author(s)
  Nakamura J, Fujimoto M, Yasuda K, Takeda K, Akira S, Hatayama T, Takagi Y, Nozaki K, Hosokawa N, Nagata K.
- Journal Title
  
  Stroke
  
  Volume: 39(10) Pages: 2853-9
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Tissue inhibitor of metalloproteinases protect blood-brain barrier disruption in focal cerebral ischemia2008
- Author(s)
  Fujimoto M, Takagi Y, Aoki T, Hayase M, Marumo T, Gomi M, Nishimura M, Kataoka H, Hashimoto N, Nozaki K.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 28(10) Pages: 1674-85
- Data Source
  KAKENHI-PROJECT-20390382
[Journal Article] Neuronal expression of Fas-associated death domain protein and caspase-8 in the perinidal parenchyma of cerebral arteriovenous malformations2007
- Author(s)
  Takagi Y, et al.
- Journal Title
  
  J Neurosurg 106
  
  Pages: 275-282
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] Cerebral aneurysm progression suppressed by blockage of endothelin B receptor.2007
- Author(s)
  Sadamasa N, Nozaki K, Takagi Y, Moriwaki T, Kawanabe Y, Ishikawa M, Hashimoto N.
- Journal Title
  
  J Neurosurg. 106(2)
  
  Pages: 330-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] Neuronal expression of Fas-associated death domain protein and caspase-8 in the perinidal parenchyma of cerebral arteriovenous malformations.2007
- Author(s)
  Takagi Y, Kikuta K, Nozaki K, Fujimoto M, Hayashi J, Hashimoto N
- Journal Title
  
  J Neurosurg. 106(2)
  
  Pages: 275-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] 脳梗塞に対する再生医療-現状と展望-2007
- Author(s)
  高木康志
- Journal Title
  
  脳神経外科ジャーナル
  
  Pages: 481-489
- NAID
  110006279434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] Expression of hypoxia-inducing factor-1 alpha and endoglin in intimal hyperplasia of the middle cerebral artery of patients with Moyamoya disease.2007
- Author(s)
  Takagi Y, et al.
- Journal Title
  
  Neurosurgery 60
  
  Pages: 338-345
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] pression of hypoxia-inducing factor-1 alpha and endoglin in intimal hyperplasia of the middle cerebral artery of patients with Moyamoya disease.2007
- Author(s)
  Takagi Y, Kikuta K, Nozaki K, Fujimoto M, Hayashi J, Imamura H, Hashimoto N.
- Journal Title
  
  Neurosurgery. 60(2)
  
  Pages: 338-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] 脳梗塞に対するES細胞由来神経幹細胞の移植2006
- Author(s)
  高木康志, 橋本信夫
- Journal Title
  
  脳卒中 28
  
  Pages: 600-605
- NAID
  10018686834
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] Administration of ex vivo-expanded bone marrow-derived endothelialprogenitor cells attenuates focal cerebral ischemia-reperfusion injury in rats.2006
- Author(s)
  Ohta T, Kikuta K, Imamura H, Takagi Y, Nishimura M, Arakawa Y, Hashimoto N, Nozaki K.
- Journal Title
  
  Neurosurgery 59
  
  Pages: 679-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Proliferarive activity through extracellular signal-regulated kinase of smooth muscle cells in the vascular walls of cerebral arteriovenous malformations.2006
- Author(s)
  Takagi Y et al.
- Journal Title
  
  Neurosurgery 58
  
  Pages: 740-748
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] 脳梗塞に対する細胞移植治療への期待-脳神経疾患への細胞移植治療の現状を含めて-2006
- Author(s)
  高木康志
- Journal Title
  
  脳循環代謝 18
  
  Pages: 104-109
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] Primate embryonic stem cell-derived neuronal progenitors transplanted into ischemic brain2006
- Author(s)
  Hayashi J, Takagi Y, Fukuda H, Imazato T, Nishimura M et al.
- Journal Title
  
  J Cereb Blood Flow Metab 26(7)
  
  Pages: 906-914
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] ES細胞を用いた脳梗塞治療2006
- Author(s)
  高木康志
- Journal Title
  
  分子血管病 5(4)
  
  Pages: 414-419
- Data Source
  KAKENHI-PROJECT-18591588
[Journal Article] Proliferarive activity through extracellular signal-regulated kinase of smooth muscle cells in the vascular walls of cerebral arteriovenous malformations.2006
- Author(s)
  Takagi Y, Kikuta K, Sadamasa N, Nozaki K, HashimotoN.
- Journal Title
  
  Neurosurgy 58
  
  Pages: 740-748
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Primate embryonic stem cell-derived neuronal progenitors transplanted into ischemic brain.2006
- Author(s)
  Hayashi J, Takagi Y, Nishimura M, Fijimoto M, Takahashi J, Hashimoto N, Nozaki K.
- Journal Title
  
  J CBFMetab 26
  
  Pages: 906-914
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Survival and differentiation of neural progenitor cells derived from embryonic stem cells and transplanted into ischemic brain.2005
- Author(s)
  Takagi Y, Nishimura M, Morizane A, Takahashi J, Nozaki K, Hayashi J, Hashimoto N
- Journal Title
  
  J Neurosurg. 103(2)
  
  Pages: 304-310
- Data Source
  KAKENHI-PROJECT-15790766
[Journal Article] Survival and differentiation of neural progenitor cells derived from embryonic stem cells and transplanted into ischemic brain.2005
- Author(s)
  Takagi Y et al.
- Journal Title
  
  J Neurosurgery 103
  
  Pages: 304-310
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.2005
- Author(s)
  Takagi Y, Takahashi J, Saiki H, Morizane A, Hayashi T, Kishi Y, Fukuda H, Okamoto Y, Koyanagi M, Ideguchi M, Hayashi H, Imazato T, Kawasaki H, Suemori H, Omachi S, Iida H, Itoh N, Nakatsuji N, Sasai Y, Hashimoto N.
- Journal Title
  
  J Clin Invest. 115(1)
  
  Pages: 102-109
- Data Source
  KAKENHI-PROJECT-15790766
[Journal Article] Survival and differentiation of neural progenitor cells derived from embryonic stem cells and transplanted into ischemic brain2005
- Author(s)
  Takagi Y, et al.
- Journal Title
  
  J Neurosurg 103
  
  Pages: 304-310
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Activation of p38 kinase in the gerbil hippocampus showing ischemic tolerance.2003
- Author(s)
  Nishimura M, Sugino T, Nozaki K, Takagi Y, Hashimoto N, Moriguchi T, Nishida E.
- Journal Title
  
  J CBFMetab 23
  
  Pages: 1052-1059
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] STAT1 is activated in neurons after ischemia and contributes to ischemic brain injury.2002
- Author(s)
  Takagi Y, Harada J, Chiarugi A, Moskowitz MA.
- Journal Title
  
  J CBFMetab 22
  
  Pages: 1311-1318
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Hypoxia-ischemia induces thioredoxin expression and nitrotyrosine formation in new-born rat brain.2002
- Author(s)
  Hattori I, Takagi Y, Nozaki K, Kondo N, Bai J, Nakamura H, Hashimoto N, Yodoi J.
- Journal Title
  
  Redox Rep 7
  
  Pages: 256-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus.2000
- Author(s)
  Sugino T, Nozaki K, Takagi Y, Hattori I, Hashimoto N, Moriguchi T, Nishida E.
- Journal Title
  
  J Neurosci 20
  
  Pages: 4506-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Phosphorylation of c-Jun NH(2)-terminal kinase and p38 mitogen-activated protein kinase after transient forebrain ischemia in mice.2000
- Author(s)
  Takagi Y, Nozaki K, Sugino T, Hattori I, Hashimoto N.
- Journal Title
  
  Neurosci Lett 294
  
  Pages: 117-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Intravenous administration of thioredoxin decreases brain damage following transient focal cerebral ischemia in mice.
- Author(s)
  Hattori I, Takagi Y, Nakamura H, Nozaki K, Sugino T, Nishimura M, Hashimoto N, Yodoi J.
- Journal Title
  
  Antioxidants ＆ Redox Signaling 6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Journal Article] Neuroprotective Role of A Peptide Inhibitor of c-Jun N-terminal Kinase on Global ischemia in Gerbils
- Author(s)
  Duysenbi S, Nozaki K, Takagi Y, Hayashi, HashimotoN.
- Journal Title
  
  (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390398
[Presentation] エストロゲン欠乏ラットのERαおよびSirt1の低下に伴うNLRP3/IL-1β/MMP-9経路の活性化と脳動脈瘤破裂との関連2023
- Author(s)
  山口真司、山口泉、高麗雅章、島田健司、多田恵曜、北里慶子、兼松康久、高木康志
- Organizer
  第266回徳島医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08500
[Presentation] 骨内シャントの有無による海綿静脈洞部硬膜動静脈瘻の臨床的特徴の違いについて2023
- Author(s)
  島田健司、山口泉、宮本健志、曽我部周、高麗雅章、山本伸昭、花岡真実、兼松康久、松崎和仁、佐藤浩一、高木康志
- Organizer
  日本脳神経外科学会第82回学術総会
- Data Source
  KAKENHI-PROJECT-22K09259
[Presentation] 当院での急性期脳底動脈閉塞に対する血管内治療成績2023
- Author(s)
  高麗雅章, 兼松康久, 島田健司, 山本伸昭, 曽我部周, 石原学, 山口泉, 山本雄貴, 黒田一駿, 高木康志
- Organizer
  第48回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08500
[Presentation] AVM surgery using intra-arterial ICG videoangiography in hybrid operating room2022
- Author(s)
  Takagi Yasushi
- Organizer
  10th European Japanese Cerebrovascular Congress
- Invited
- Data Source
  KAKENHI-PROJECT-22K09259
[Presentation] 卵巣摘出ラットにおけるERαおよびSirt１の減少を介したNLRP3の活性と脳動脈瘤破裂の関連2022
- Author(s)
  山口真司、高麗雅章、島田健司、多田恵曜、北里慶子、兼松康久、高木康志
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09326
[Presentation] ERαおよびSirt１の減少を介したNLRP3の活性が卵巣摘出ラットの脳動脈瘤破裂に影響する2022
- Author(s)
  山口真司、宮本健志、四方英二、島田健司、多田恵曜、高麗雅章、北里慶子、兼松康久、高木康志
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-20K09391
[Presentation] 卵巣摘出ラットにおけるERαおよびSirt１の減少を介したNLRP3の活性と脳動脈瘤破裂の関連2022
- Author(s)
  山口真司、高麗雅章、島田健司、多田恵曜、北里慶子、兼松康久、高木康志
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09391
[Presentation] ERαおよびSirt１の減少を介したNLRP3の活性が卵巣摘出ラットの脳動脈瘤破裂に影響する2022
- Author(s)
  山口真司、宮本健志、四方英二、島田健司、多田恵曜、高麗雅章、北里慶子、兼松康久、高木康志
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-20K09326
[Presentation] 海綿静脈洞部硬膜動静脈瘻におけるshunted pouchと頭蓋底骨の関係2020
- Author(s)
  島田健司、山口泉、宮本健志、曽我部周、三宅一央、花岡真実、兼松康久、松崎和仁、佐藤浩一、高木康志
- Organizer
  第36回NPO法人日本脳神経血管内治療学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09391
[Presentation] 内頸動脈管径とRNF213遺伝子多型によるもやもや病の診断2015
- Author(s)
  森本貴昭、峰晴陽平、坂井信幸、高木康志、人見敏明、小林果、谷正一、上野泰、今村博敏、藤堂謙一、松田佳子、小泉昭夫、宮本享
- Organizer
  第27回日本脳循環代謝学会総会
- Place of Presentation
  富山国際会議場
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25253047
[Presentation] もやもや病感受性多型RNF213遺伝子p.R4810Kによるangiogenesis抑制のin vitroおよびin vivoでの検討2015
- Author(s)
  松田佳子、小林果、人見敏明、奥田裕子、塩井大智、原田浩二、峰晴陽平、高木康志、宮本享、小泉昭夫
- Organizer
  第27回日本脳循環代謝学会総会
- Place of Presentation
  富山国際会議場
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25253047
[Presentation] In vitro and in vivo evidence on inhibition of angiogenesis by the Moyamoya susceptible gene and its mutation, RNF213 R4810K2015
- Author(s)
  Koizumi A, Kobayashi H, Matsuda Y, Hitomi T, Okuda H, Shioi H, Matsuda T, Imai H, Sone M, Taura D, Harada KH, Takagi Y, Miyamoto S, Habu T.
- Organizer
  4th International Moyamoya Meeting Berlin
- Place of Presentation
  Berlin
- Year and Date
  2015-07-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253047
[Presentation] Mysterin/RNF213 p.R4810K変異からみたもやもや病の特徴2015
- Author(s)
  峰晴陽平、高木康志、森本貴昭、松田佳子、小林果、人見敏明、原田浩二、宮本享、小泉昭夫
- Organizer
  第27回日本脳循環代謝学会総会
- Place of Presentation
  富山国際会議場
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25253047
[Presentation] 脳虚血における神経幹細胞研究の歴史と現状2014
- Author(s)
  高木康志
- Organizer
  第26回日本脳循環代謝学会
- Place of Presentation
  岡山
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-25293308
[Presentation] 胚性幹細胞、人工多能性幹細胞由来神経幹細胞の虚血脳への移植-現状と課題について-2012
- Author(s)
  高木康志
- Organizer
  日本脳卒中学会総会
- Place of Presentation
  福岡市
- Year and Date
  2012-04-27
- Data Source
  KAKENHI-PROJECT-20390382
[Presentation] Transplantation of stem cells and clinical applications2007
- Author(s)
  Yasushi Takagi
- Organizer
  19^<th> annual meeting of Japanese society of cerebral blood flow and metabolism
- Place of Presentation
  Morioka
- Year and Date
  2007-10-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591588
[Presentation] 脳梗塞に対する再生医療2007
- Author(s)
  高木康志
- Organizer
  日本脳循環代謝学会
- Place of Presentation
  盛岡市
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18591588
[Presentation] 幹細胞移植とその臨床応用2007
- Author(s)
  高木康志
- Organizer
  第19回日本脳循環代謝学会総会
- Place of Presentation
  盛岡
- Year and Date
  2007-10-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591588

1. MIYAMOTO Susumu (70239440)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. SHIMADA Kenji (60624351)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
3. KANEMATSU Yasuhisa (90363142)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
4. 宮本健志 (80585000)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
5. NOZAKI Kazuhiko (90252452)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
6. HASHIMOTO Nobuo (40135570)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
7. TAKAHASHI Jun (10270779)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
8. 多田恵曜 (30547964)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
9. 高麗雅章 (60794013)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
10. 山口泉 (70780005)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
11. TAKAHASHI Jun (90551408)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KOIZUMI Akio (50124574)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
13. Takeshi Funaki (70555094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
14. 八木謙次 (80551837)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. 四方英二 (30813315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
16. YOSHIDA Kazumichi (90598921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ARAI Hidenori (60232021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OKADA Tomohisa (30321607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. SATO Yasufumi (50178779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SONE Masakatsu (40437207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. HABU Toshiyuki (70346071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. YAMAZAKI Satoru (70348796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. HARADA Koji (80452340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
24. HITOMI Toshiaki (90405275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
25. NISHIDA Eisuke (60143369)

# of Collaborated Projects: 1 results

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26. 林拓也 (50372115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 森實飛鳥 (10528730)

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28. 荒川芳輝 (20378649)

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# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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33. KATAOKA hiroharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
34. SAHOKO Ichihara

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. KOBAYASHI Hatasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
36. NARUISHI Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. MATSUDA yoshiko

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# of Collaborated Products: 1 results
38. MATSUDA fumihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 山本健

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40. 横田充弘

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# of Collaborated Projects: 0 results

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42. 中杤昌弘

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44. 森潔

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45. SHOHAB YOUSSEFIAN

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 原慶次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takagi Yasushi 高木 康志

高木 康志 タカギ ヤスシ

TAKAGI Yasushi 高木 康志

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脳動静脈奇形における血管内皮のKRAS変異とPAD4活性化の関係Principal Investigator

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Transplantation of iPS cell-derived neuronal stem cells into ischemic brainPrincipal Investigator

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Stroke therapy using embryonic stem cells and bone marrow stromal cell-derived neuralstem cellsPrincipal Investigator

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Transplantation of primate embryonic stem cell-derived neural stem cell against brain ischemiaPrincipal Investigator

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Takagi Yasushi 高木康志

高木康志タカギヤスシ

TAKAGI Yasushi 高木康志