takino takahisa 滝野隆久

… Alternative Names

Takino Takahisa 滝野隆久

滝野隆久タキノタカヒサ

TAKINO Takahisa 滝野隆久

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Researcher Number	40322119
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, GS教育系, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 金沢大学, GS教育系, 教授 2018: 金沢大学, GS教育系, 教授 2017: 金沢大学, 国際基幹教育院, 教授 2016: 金沢大学, 国際基幹教育院, 准教授 2011 – 2013: 金沢大学, がん進展制御研究所, 准教授 … More 2007 – 2010: Kanazawa University, Cancer Research Institute, Associate Professor 2003 – 2006: Kanazawa University, Cancer Research Institute, Associate Professor, がん研究所, 助教授 2000 – 2002: 金沢大学, がん研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Pathological medical chemistry / Pathological medical chemistry / Basic Section 50010:Tumor biology-related Except Principal Investigator Pathological medical chemistry / Basic Section 55020:Digestive surgery-related / Tumor biology / Pathological medical chemistry / Biological Sciences
Keywords	Principal Investigator 細胞運動 / 浸潤 / 細胞外マトリックス / インテグリン / 情報伝達 / MMP / MAPK / JNK / MT1-MMP / ERK … More / ECM / 分解 / MT-MMP / Invasion / Cancer / がん / がん浸潤 / がん細胞 / 極性 / 細胞浸潤 / 情報伝達機構 / 分解酵素 / FAK / 微小環境 / 線維芽細胞 / がん微小環境 / がん転移 / マトリックスメタロプロテアーゼ / 細胞外マトリックス分解酵素 / Cell migration / Extracellular Matrix / Cell Migration / 細胞極性 / 細胞接着 / 運動 / 癌細胞 / シグナル / 細胞外環境 / シグナル伝達 / 増殖 / 細胞外微小環境 / 転移 / JSAPI / リン酸化 / PTEN / Scaffold protein / CrkII … More Except Principal Investigator MT1-MMP / p53 / GDF15 / MMP-2 / 細胞外マトリックス / 転移 / KiSS-1 / N-Tes / APP / がん / 悪性化 / 細胞運動 / 浸潤 / コラーゲン / ルミカン / シンデカン / テスティカン / 遊走抑制効果 / 浸潤抑制効果 / 殺細胞活性 / UTX-143 / アミロライド / Na+/H+交換輸送体5 / 浸潤・転移 / 肝臓 / 浸潤転移 / 膜型マトリックスメタロプロテアーゼ / Invasion / HIF / EphA2 / がん微小環境 / ラミニン / 肝細胞がん / CD90 / EpCAM / Mint3 / HIF-1 / がんの増殖・浸潤・転移 / がん幹細胞 / 肝臓がん / alpha secretase / Cancer / inflammatory diseases / Apolipoprotein E / 転写活性化 / Fe65 / セレクターゼ / 癌 / MT-MMP / 増殖抑制 / TGFベーター / ベーターアミロイド / アルファーセクレターゼ / 炎症性疾患 / アポリポプロテインE / Collagen / Lumican / Syndecan / Mtastasis / Testican / HT-1080 / GPCR / metastin / 幹細胞 / 運動 / KIM-1 / HAI-1 / シェディング / プロテアーゼ / がん転移 / p21 / 活性化 / TIMP-2 / 分子標的 / ERK / 細胞接着斑 / GDF-15 / 組織破壊 / 腎臓 / ゼラチン / 発現制御 / 形態形成 / Rho / Rac / RalA / Testican-3 / Claudin-5 / グリオーマ / クローディン / 阻害 / 脳 / RT-PCR Less

Cross-talk between cancer cells and fibroblasts during cancer progression.Principal Investigator
- Principal Investigator
  
  Takino Takahisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Development of a selective inhibitor against Na+/H+ exchange transporter 5 (NHE5), which is a target candidate molecule for gastrointestinal cancer.
- Principal Investigator
  
  Ninomiya Itasu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kanazawa University
Analysis of MT1-MMP-dependent molecular pathways in the diversity and transformation of hepatocellular carcinoma
- Principal Investigator
  
  Seiki Motoharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
A molecular mechanism that regulates extracellular matrix degradation and cell polarity in migrating cells.Principal Investigator
- Principal Investigator
  
  TAKINO Takahisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Study on role of membrane-type matrix metalloproteinase-1 in tumor malignancy
- Principal Investigator
  
  SATO Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
膜型マトリックスメタロプロテアーゼによる細胞運動極性制御機構Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Cell migration induced by alternation of extracellular matrix microenvironmentPrincipal Investigator
- Principal Investigator
  
  TAKINO Takahisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Study on mechanism of tissue degradation by membrane-type matrix metalloproteinase
- Principal Investigator
  
  SATO Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Analysis of a molecular mechanism by which JNK-binding proteins regulate turnover of focal adhesions and formAnalysis of a molecular mechanism by which JNK-binding proteins regulate turnover of focal adhesions and formation of cell polarityPrincipal Investigator
- Principal Investigator
  
  TAKINO Takahisa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Functional analysis of matrix metalloproteinases associated with tissue destruction
- Principal Investigator
  
  SATO Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
がん浸潤の細胞運動と細胞外マトリックス分解機構の解析Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Analysis of regulatory mechanism for cell polarity formation by JNK binding molecules during migrationPrincipal Investigator
- Principal Investigator
  
  TAKINO Takahisa
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
癌細胞浸潤における細胞運動とMT-MMPの協調的制御機構の解析Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
癌浸潤における細胞運動とMT-MMPの協調的制御機構の解析Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
がん細胞運動とマトリックスメタロプロテアーゼ活性発現の協調的制御機構の解析Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Study on novel functions of membrane-type matrix metalloproteinase in tumor metastasis
- Principal Investigator
  
  SATO Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
がん浸潤における細胞運動とMMP発現の協調的制御機構の解析Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
がん浸潤における細胞運動とMMP発現の協調的制御機構の解析Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
癌細胞運動とマトリックスメタロプロテアーゼ活性発現調節機構の解明Principal Investigator
- Principal Investigator
  
  滝野隆久
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
形態形成過程におけるMT1-MMPの機能発現制御機構の解析
- Principal Investigator
  
  SATO Hiroshi
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University

[Journal Article] Development of UTX-143, a selective sodium-hydrogen exchange subtype 5 inhibitor, using amiloride as a lead compound2024
- Author(s)
  Shinohara Yusei、Komiya Yuki、Morimoto Kashin、Endo Yoshio、Terashima Minoru、Suzuki Takeshi、Takino Takahisa、Ninomiya Itasu、Yamada Hisatsugu、Uto Yoshihiro
- Journal Title
  
  Bioorganic and Medicinal Chemistry
  
  Volume: 99 Pages: 117603-117603
- DOI
  10.1016/j.bmc.2024.117603
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07147, KAKENHI-PROJECT-21K07118
[Journal Article] ASH2L, a COMPASS core subunit, is involved in the cell invasion and migration of triple-negative breast cancer cells through the epigenetic control of histone H3 lysine 4 methylation2023
- Author(s)
  Batbayar Gerelsuren、Ishimura Akihiko、Lyu Hanbing、Wanna-udom Sasithorn、Meguro-Horike Makiko、Terashima Minoru、Horike Shin-ichi、Takino Takahisa、Suzuki Takeshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 669 Pages: 19-29
- DOI
  10.1016/j.bbrc.2023.05.061
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06880, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K07146, KAKENHI-PROJECT-22K07147, KAKENHI-PROJECT-21K07118
[Journal Article] m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF--induced epithelial-mesenchymal transition of lung cancer cells.2022
- Author(s)
  Suphakhong K, Terashima M, Wanna-Udom S, Takatsuka R, Ishimura A, Takino T, Suzuki T.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 11 Pages: 102554-102554
- DOI
  10.1016/j.jbc.2022.102554
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07118, KAKENHI-PROJECT-22K06880, KAKENHI-PROJECT-22K07146, KAKENHI-PROJECT-22K07147
[Journal Article] Structure–Activity Relationships of UTX-121 Derivatives for the Development of Novel Matrix Metalloproteinase-2/9 Inhibitors2021
- Author(s)
  Yamahana H, Komiya Y, Takino T, Endo Y, Yamada H, Asada C, Uto Y
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 10 Pages: 1017-1028
- DOI
  10.1248/cpb.c21-00549
- NAID
  130008095540
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07118
[Journal Article] KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial-mesenchymal transition in lung and pancreatic cancer cell lines2021
- Author(s)
  Wanna-Udom Sasithorn、Terashima Minoru、Suphakhong Kusuma、Ishimura Akihiko、Takino Takahisa、Suzuki Takeshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100213-100213
- DOI
  10.1074/jbc.ra120.015502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06057, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-19K07346, KAKENHI-PROJECT-19K07686, KAKENHI-PROJECT-21K07118
[Journal Article] TGF-β1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells2021
- Author(s)
  Yamahana Hirari、Terashima Minoru、Takatsuka Risa、Asada Chikako、Suzuki Takeshi、Uto Yoshihiro、Takino Takahisa
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 27 Pages: 101072-101072
- DOI
  10.1016/j.bbrep.2021.101072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07346, KAKENHI-PROJECT-21K07118, KAKENHI-PROJECT-16H06279
[Journal Article] Simple and cost-effective assay for isolating invasive living cells2018
- Author(s)
  Takino Takahisa、Sato Hiroshi、Seiki Motoharu
- Journal Title
  
  BioTechniques
  
  Volume: 65 Issue: 3 Pages: 137-142
- DOI
  10.2144/btn-2018-0036
- NAID
  120006605145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04695
[Journal Article] MT1-MMP prevents growth inhibition by three dimensional fibronectin matrix2013
- Author(s)
  Takino T, Guo L, Domoto T, Sato H
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 436 Issue: 3 Pages: 503-508
- DOI
  10.1016/j.bbrc.2013.05.134
- NAID
  120005302290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590356
[Journal Article] Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival2013
- Author(s)
  Teng L, Nakada M, Furuyama N, Sabit H, Furuta T, Hayashi Y, Takino T, Dong Y, Sato H, Sai Y, Miyamoto KI, Berens ME, Zhao SG, Hamada JI
- Journal Title
  
  Neuro-Oncology
  
  Volume: 15 Issue: 12 Pages: 1710-1720
- DOI
  10.1093/neuonc/not128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590356, KAKENHI-PROJECT-23592117
[Journal Article] Integrinα3 is overexpressed in glioma stem-like cells and promotes invasion2013
- Author(s)
  Nakada M, Nambu E, Furuyama N, Yoshida Y, Takino T, Hayashi Y, Sato H, Sai Y, Tsuji T, Miyamoto KI, Hirao A, Hamada JI
- Journal Title
  
  Br itish J our nal of Cancer
  
  Volume: 108 Pages: 2516-2524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590356
[Journal Article] Integrinα3 is overexpressed in glioma stem-like cells and promotes invasion2013
- Author(s)
  Nakada M, Nambu E, Furuyama N, Yoshida Y, Takino T, Hayashi Y, Sato H, Sai Y, Tsuji T, Miyamoto KI, Hirao A, Hamada JI
- Journal Title
  
  Br J Cancer
  
  Volume: 108 Issue: 12 Pages: 2516-2524
- DOI
  10.1038/bjc.2013.218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590092, KAKENHI-PROJECT-23590356
[Journal Article] Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy2013
- Author(s)
  Kitano A
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 2 Pages: 15-15
- DOI
  10.1371/journal.pone.0055289
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-22790542, KAKENHI-PUBLICLY-23120703, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23590356, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-23659643, KAKENHI-PROJECT-25460793, KAKENHI-PROJECT-25670572
[Journal Article] Shedding of kidney injury molecule-1 by membrane-type 1 matrix metalloproteinase2012
- Author(s)
  Guo L, Takino T, Endo Y, Domoto T, Sato H
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 152 Issue: 5 Pages: 425-432
- DOI
  10.1093/jb/mvs082
- NAID
  10031166158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590356
[Journal Article] Cleavage of hepatocyte growth factor activator inhibitor-1 by membrane-type MMP-1 activates matriptase2012
- Author(s)
  Domoto T, Takino T, Guo L, Sato, H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 103 Issue: 3 Pages: 448-454
- DOI
  10.1111/j.1349-7006.2011.02162.x
- NAID
  120005767273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390091, KAKENHI-PROJECT-23590356
[Journal Article] Membrane-type 1 matrix metalloproteinase regulates fibronectin assembly to promote cell motility2011
- Author(s)
  Takino T, Nagao R, Manabe R, Domoto T, Sekiguchi K, Sato H.
- Journal Title
  
  FEBS Let
  
  Volume: 585 Issue: 21 Pages: 3378-3384
- DOI
  10.1016/j.febslet.2011.09.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390091, KAKENHI-PROJECT-23590356
[Journal Article] MTl-MMP promotes cell growth and ERK activation through c-Sre and paxillin in three-dimensional collagen matrix.2010
- Author(s)
  Takino T
- Journal Title
  
  Biochem. Biophys. Res.Commun.
  
  Volume: 364 Pages: 1042-1047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390091
[Journal Article] MT1-MMP promotes cell growth and ERK activation through c-Src and paxillin in three-dimensional collagen matrix2010
- Author(s)
  Takino T, Tsuge H, Ozawa T, Sato H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 3964 Issue: 4 Pages: 1042-1047
- DOI
  10.1016/j.bbrc.2010.05.059
- NAID
  120002224339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390091
[Journal Article] GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase.2010
- Author(s)
  Sakr, M., Takino, T., Domoto, T., Nakano, H., Wong, R., Sasaki, M., Nakanuma, Y., Sato, H.
- Journal Title
  
  Cancer Science 101
  
  Pages: 2368-2374
- NAID
  10027833432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion.2010
- Author(s)
  Sato, H., Takino, T.
- Journal Title
  
  Cancer Science 101
  
  Pages: 843-847
- NAID
  10026590425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] Coordinate action of membrane-type matrix metalloproteinase-1(MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion2010
- Author(s)
  Sato H, Takino T.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Issue: 4 Pages: 843-947
- DOI
  10.1111/j.1349-7006.2010.01498.x
- NAID
  10026590425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390091
[Journal Article] Coordinate action of membrane-type matrix metalloproteinase-1(MT1-MMP)and MMP-2 enhances pericellular proteolysis and invasion2010
- Author(s)
  佐藤博, 滝野隆久
- Journal Title
  
  Cancer Science 101
  
  Pages: 843-847
- NAID
  10026590425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] Coordinate action of membrane-type matrix metalloproteinase-1(MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion2010
- Author(s)
  H.Sato, T.Takino
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 843-847
- NAID
  10026590425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase2010
- Author(s)
  Sakr MA, Takino T, Domoto T, Nakano H, Wong RW, Sasaki M, Nakanuma Y, Sato H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Issue: 11 Pages: 2368-2374
- DOI
  10.1111/j.1349-7006.2010.01675.x
- NAID
  10027833432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390091
[Journal Article] Coordinate action of membrane-type matrix metalloproteinase-1(MT1-MMP)and MMP-2 enhances pericellular proteolysis and invasion2010
- Author(s)
  H.Sato, T.Takino
- Journal Title
  
  Cancer Science 101
  
  Pages: 843-847
- NAID
  10026590425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013017
[Journal Article] MT1-MMP promotes cell growth and ERK activation through c-Src and paxillin in three-dimentional collagen matrix.2010
- Author(s)
  Takino, T., Tsuge, H., Ozawa, T., Sato, H.
- Journal Title
  
  Biochemical and Biophysical Research Communications 396
  
  Pages: 1042-1047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] MTl-MMP promotes cell growth and ERK activation through c-Src and paxillin inthree-dimentional collagen matrix2010
- Author(s)
  T.Takino, 他3名、1番目
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 396 Pages: 1042-1047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] 細胞運動能、浸潤能、マトリックスメタロプロテアーゼアッセイ法2009
- Author(s)
  滝野隆久、佐藤博
- Journal Title
  
  がん分子標的治療研究実践マニュアル
  
  Pages: 106-113
- Data Source
  KAKENHI-PROJECT-20013017
[Journal Article] 細胞運動能、浸潤能、マトリックスメタロプロテアーゼアッセイ法2009
- Author(s)
  滝野隆久、佐藤博
- Journal Title
  
  がん分子標的治療研究実践マニュアル
  
  Pages: 106-113
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] Activation of Matrix Metalloproteinase (MMP)-2 By Membrane-type 1-MMP Through An Artificial Receptor For ProMMP-2 Generates Active MMP-22008
- Author(s)
  Nishida Y, Miyamori H, Thompson E.W, Takino T., Endo Y., Sato H.
- Journal Title
  
  Cancer Res. 68
  
  Pages: 9096-9104
- Data Source
  KAKENHI-PROJECT-19390084
[Journal Article] The scaffold protein c-Jun NH_2-terminal kinase-associated leucine zipper protein regulates cell migration through interaction with the G protein G (alpha 13).2008
- Author(s)
  Gantulga, D., Tuvshintugs, B., Endo, Y., Takino, T., Sato, H., Murakami, S., Yoshioka, K.
- Journal Title
  
  Journal of Biochemistry 144
  
  Pages: 693-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] The scaffold protein c-Jun NH2-terminal kinase-associated leucine zipper protein regulates cell migration through interaction with the G protein Gα132008
- Author(s)
  Gantulga D, Baljinnyam Tuvshintugs B, Endo Y, Takino T, Sato H, Murakami S, Yoshioka K.
- Journal Title
  
  J. Biochemistry 114
  
  Pages: 693-700
- Data Source
  KAKENHI-PROJECT-19390084
[Journal Article] Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.2008
- Author(s)
  Nishida, Y., Miyamori, H., Thompson, E.W., Takino, T., Endo, Y., Sato, H.
- Journal Title
  
  Cancer Research 68
  
  Pages: 9096-9104
- NAID
  120000997250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590306
[Journal Article] Regulation of N-cadherin-based cell-cell interaction by JSAP1 scaffold in PC12h cells2007
- Author(s)
  Bayarsaikhan B., Takino T., Gantulga D., Sato H., Ito T. Yoshioka K
- Journal Title
  
  Biochem.Biophys.Res.Commum 353
  
  Pages: 357-362
- NAID
  120000809366
- Data Source
  KAKENHI-PROJECT-19390084
[Journal Article] Inhibition of membrane-type 1 matrix metalloproteinase at cell-matrix adhesions2007
- Author(s)
  Takino, T., Saeki, H., Miyamori, H., Kudo, T., Sato, H
- Journal Title
  
  Cancer Research 67
  
  Pages: 11621-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Inhibition of Membrane-Type Matrix Metalloproteinase at Cell-Matrix Adhesions2007
- Author(s)
  Takino T., Saeki H., Miyamori H., Kudo T., Sato H.
- Journal Title
  
  Cancer Res 67
  
  Pages: 11621-11629
- Data Source
  KAKENHI-PROJECT-19390084
[Journal Article] Inhibition of Membrane-Type Matrix Metalloproteinase at Cell-Matrix Adhesions.2007
- Author(s)
  Takahisa Takino
- Journal Title
  
  Cancer Research 67
  
  Pages: 11621-11629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390084
[Journal Article] Regulation of N-cadherin- based cell-cell interaction by JSAP1 scaffold in PC12h cells2007
- Author(s)
  Bayarsaikhan, M., Takino, T., Gantulga, D., Sato, H., Ito, T., Yoshioka, K
- Journal Title
  
  Biochem. Biophys. Res. Commun 353
  
  Pages: 357-362
- NAID
  120000809366
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Inhibition of membranetype 1 matrix metalloproteinase at cell-matrix adhesions.2007
- Author(s)
  T.Takino., et. al.(他4名、1番目)
- Journal Title
  
  Cancer Research 67
  
  Pages: 11621-11629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Cleavage of growth differentiation factor 15 (GDF15) by membrane type 1-matrix metalloproteinase abrogates GDF15-mediated suppression of tumor cell growth2007
- Author(s)
  Abd El-Aziz SH., Endo Y., Miyamaori H., Takino T., Sato H.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1330-1335
- NAID
  10019998291
- Data Source
  KAKENHI-PROJECT-19390084
[Journal Article] Substrate choice of membrane-type matrix metalloproteinase-1 is dictated by tissue inhibitor of matrix metalloproteinase-2 levels.2007
- Author(s)
  Kudo T., Takino T., Miyamori H., Thompson E.W., Sato H.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 563-568
- Data Source
  KAKENHI-PROJECT-19390084
[Journal Article] Cleavage of growth differentiation factor 15 (GDF15) by membrane type I-matrix metalloproteinase abrogates GDF15-mediated suppression of tumor cell growth2007
- Author(s)
  Abd, El-Aziz, S., H., Endo, Y., Miyamaori, H., Takino, T., Sato, H
- Journal Title
  
  Cancer Science 98
  
  Pages: 1330-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] choice of membrane-type 1 matrix metalloproteinase is dictated by tissue inhibitor of metalloproteinase-2 level2007
- Author(s)
  Kudo, T., Takino., T., Miyamori, H., Thompson, E. W., Sato, H
- Journal Title
  
  Cancer Science 98
  
  Pages: 563-568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Inhibition of membrane-type 1 matrix metalloproteinase at cell-matrix adhesions.2007
- Author(s)
  T. Takino, et. al.(他4名、1番目)
- Journal Title
  
  Cancer Research 67
  
  Pages: 11621-11629
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.2006
- Author(s)
  Takahisa Takino
- Journal Title
  
  Experimental Cell Research 312・8
  
  Pages: 1381-1389
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390090
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.2006
- Author(s)
  T.Takino et al.
- Journal Title
  
  Experimental Cell Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration2006
- Author(s)
  Takahisa Takino
- Journal Title
  
  Experimental Cell Research 312・8
  
  Pages: 1381-1389
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390090
[Journal Article] Memobrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.2006
- Author(s)
  Takahisa Takino
- Journal Title
  
  Experimental Cell Research 312・8
  
  Pages: 1381-1389
- Data Source
  KAKENHI-PROJECT-17390090
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.2006
- Author(s)
  Takino T, et al.
- Journal Title
  
  Experimental Cell Research (印刷中)
- Data Source
  KAKENHI-PROJECT-17390090
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.2006
- Author(s)
  T.Takino et al.
- Journal Title
  
  Experimental Cell Research (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Cleavage of amyloid-precursor protein (APP) by membrane-type matrix metalloproteinases2006
- Author(s)
  Ahmad, M., Takino.T., Miyamori, H., Yoshizaki, T., Furukawa, M., Sato, H
- Journal Title
  
  J. Biochem 139
  
  Pages: 517-526
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration2006
- Author(s)
  Takino, T., Watanabe, Y., Matsui, M., Miyamori, H., Kudo, T., Seiki, M., Sato, H.
- Journal Title
  
  Exp. Cell Res 312
  
  Pages: 1381-1389
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.2006
- Author(s)
  T. Takino, et. al.(他6名、1番目)
- Journal Title
  
  Experimental Cell Research 312
  
  Pages: 1381-1389
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.2006
- Author(s)
  T.Takino, 他6名(1番目)
- Journal Title
  
  Experimental Cell Research 312
  
  Pages: 1381-1389
- Data Source
  KAKENHI-PROJECT-18590287
[Journal Article] Membrane-type 1 matrix metalloproteinase modulates focal adhesion Stability and cell migration.2006
- Author(s)
  T.Takino et al.
- Journal Title
  
  Experimental Cell Research (印刷中)
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Cleavage of apolipoprotein e by membrane-type matrix metalloproteinase-1 abrogates suppression of cell proliferation2005
- Author(s)
  T.Aoki, D.Sato, Y.Li, T.Takino, H.Miyamori, H.Sato
- Journal Title
  
  J.Biochem. 137
  
  Pages: 95-99
- NAID
  10017342715
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] JSAP1/JIP3 cooperates with FAK to regulate c-Jun N-terminal kinase and cell migration.2005
- Author(s)
  T.Takino et al.
- Journal Title
  
  The Journal of Biological Chemistry 280
  
  Pages: 37772-37781
- NAID
  120000814860
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] JSAP1/JIP3 cooperates with FAK to regulate c-Jun N-terminal kinase and cell migration2005
- Author(s)
  Takahisa Takino
- Journal Title
  
  J. Biol. Chem. 280・45
  
  Pages: 37772-37781
- NAID
  120000814860
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390090
[Journal Article] JSAP1/JIP3 cooperates with FAK to regulate c-Jun N-terminal kinase and cell migration.2005
- Author(s)
  Takino T, et al.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 37772-37781
- NAID
  120000814860
- Data Source
  KAKENHI-PROJECT-17390090
[Journal Article] JSAP1/JIP3 cooperates with FAK to regulate c-Jun N-terminal kinase And cell migration,2005
- Author(s)
  T.Takino et al.
- Journal Title
  
  The Journal of Biological Chemistry 280
  
  Pages: 37772-37781
- NAID
  120000814860
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] JSAP1/JIP3 cooperates with FAK to regulate c-Jun N-terminal kinase and cell migration.2005
- Author(s)
  T.Takino et al.
- Journal Title
  
  The Journal of Biological Chemistry, 280
  
  Pages: 37772-37781
- NAID
  120000814860
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Cleavage of apolipoprotein e by membrane-type matrix metalloproteinase-1 abrogates suppression of cell proliferation2005
- Author(s)
  T.Aoki, D.Sato, Y.Li, T.Takino, H.Miyamori, H.Sato
- Journal Title
  
  J.Biochem. 137
  
  Pages: 95-99
- NAID
  10017342715
- Data Source
  KAKENHI-PROJECT-16022227
[Journal Article] JSAP1/JIP3 cooperates with FAK to regulate c-Jun N-terminal kinase and cell migration.2005
- Author(s)
  Takahisa Takino
- Journal Title
  
  J. Biol. Chem. 280・45
  
  Pages: 37772-37781
- NAID
  120000814860
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390090
[Journal Article] Cleavage of lumican by membrane-type matrix metalloproteinase-1 abrogates this proteoglycan-mediated suppression of tumor cell colony formation in soft agar.2004
- Author(s)
  Y.Li, T.Aoki, Y.Mori, M.Ahmad, H.Miyamori, T.Takino, H.Sato.
- Journal Title
  
  Cancer Research 64
  
  Pages: 7058-7064
- NAID
  120000813425
- Data Source
  KAKENHI-PROJECT-16022227
[Journal Article] Membrane-typel matrix metalloproteinase regulates collagen-dependent mitogen-activated protein/extracellular signal-regulated kinase activation and cell migration.2004
- Author(s)
  T.Takino, H.Miyamori, Y.Watanabe, K.Yoshioka, M.Seiki, H.Sato
- Journal Title
  
  Cancer Research 64
  
  Pages: 1044-4049
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Increased matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase activity and expression in heterotopically transplanted murine tracheas.2004
- Author(s)
  N.Inaki, Y.Tsunezuka, K.Kawakami, H.Sato, T.Takino, M.Oda, G.Watanabe
- Journal Title
  
  J.Heart Lung Transplantation 23
  
  Pages: 218-227
- Data Source
  KAKENHI-PROJECT-16022227
[Journal Article] Anti-metastatic effect of capecitabine on human colon cancer xenografts in nude mouse rectum.2004
- Author(s)
  I.Ninomiya, I.Terada, T.Yoshizumi, T.Takino, 他7名
- Journal Title
  
  Int.J.Cancer 112
  
  Pages: 135-142
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Anti-metastatic effect of capecitabine on human colon cancer xenografts in nude mouse rectum.2004
- Author(s)
  I.Ninomiya, I.Terada, T.Yoshizumi, T.Takino, 他7名
- Journal Title
  
  Int.J.Cancer 112
  
  Pages: 135-142
- Data Source
  KAKENHI-PROJECT-16022227
[Journal Article] Cleavage of lumican by membrane-type matrix metalloproteinase-1 abrogates this proteoglycan-mediated suppression of tumor cell colony formation in soft agar.2004
- Author(s)
  Y.Li, T.Aoki, Y.Mori, M.Ahmad, H.Miyamori, T.Takino, H.Sato
- Journal Title
  
  Cancer Research 64
  
  Pages: 7058-7064
- NAID
  120000813425
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Increased matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase activity and expression in heterotopically transplanted murine tracheas.2004
- Author(s)
  N.Inaki, Y.Tsunezuka, K.Kawakami, H.Sato, T.Takino, M.Oda, G.Watanabe
- Journal Title
  
  J.Heart Lung Transplantation 23
  
  Pages: 218-227
- Data Source
  KAKENHI-PROJECT-16590241
[Journal Article] Membrane-type1 matrix metalloproteinase regulates collagen-dependent mitogen-activated protein/extracellular signal-regulated kinase activation and cell migration.2004
- Author(s)
  T.Takino, H.Miyamori, Y.Watanabe, K.Yoshioka, M.Seiki, H.Sato
- Journal Title
  
  Cancer Research 64
  
  Pages: 1044-4049
- Data Source
  KAKENHI-PROJECT-16022227
[Patent] 生体組織から線維芽細胞を単離する方法およびそれに用いるキット2017
- Inventor(s)
  滝野隆久、遠藤良夫、二宮致、清木元治
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 鉄はMT1-MMPによるMMP-2活性化と細胞浸潤を制御する2023
- Author(s)
  滝野隆久
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] MT1-MMP活性化を介してヒト小細胞肺がん細胞株DMS273の浸潤及び転移形成を促進するクローディン2023
- Author(s)
  坂本修一、滝野隆久、川田学、畠山昌則
- Organizer
  第82回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] ASH2Lは、ヒストンH2K4メチル化修飾を介して、トリプルネガティヴ型乳がん細胞の悪性化形質を調整する2023
- Author(s)
  石村昭彦、寺島農、滝野隆久、鈴木健之
- Organizer
  第82回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] 鉄はMT1-MMPによるMMP-2活性化を介して細胞浸潤を制御する2023
- Author(s)
  滝野隆久、高塚理沙、鈴木健之
- Organizer
  第82回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] 鉄はMT1-MMPによるMMP-2活性化と細胞浸潤を制御する2023
- Author(s)
  滝野隆久
- Organizer
  第32回　日本がん転移学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] 小細胞肺がんの自然転移モデルにおいて遠隔転移形成を促進するクローディンの機能解析2023
- Author(s)
  坂本修一、井上裕祥、滝野隆久、幸田泰子、大庭俊一、宇佐美伊保美、川田学、畠山昌則
- Organizer
  第32回　日本がん転移学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] Na+/H+ 交換輸送体５(NHE5)選択的阻害剤であるアミロライド誘導体の構造活性相関によるUTX-143の創薬2021
- Author(s)
  小宮悠生、篠原侑成、二宮致、遠藤良夫、滝野隆久、宇都義浩
- Organizer
  第80回本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] 抗転移リード化合物としてセレコキシブから派生したUTX-121誘導体構造活性相関2021
- Author(s)
  前田宗太郎、山花啓梨、遠藤良夫、滝野隆久、宇都義浩
- Organizer
  第80回本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07118
[Presentation] 浸潤細胞の捕獲を目的としたアッセイ法の開発2018
- Author(s)
  滝野隆久、清木元治
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] MT1-MMPによる細胞接着ネットワークの制御2013
- Author(s)
  滝野隆久、堂本貴寛、佐藤博
- Organizer
  第22回　日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPは3次元フィブロネクチンマトリックス由来の増殖抑制を回避する2013
- Author(s)
  滝野隆久, 佐藤博
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-02
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMP prevents growth inhibition from three dimensional2013
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第72回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによる細胞接着ネットワークの制御2013
- Author(s)
  滝野隆久, 堂本貴寛, 佐藤博
- Organizer
  第22回日本がん転移学会学術総会
- Place of Presentation
  ホテルブエナビスタ松本(長野県)
- Year and Date
  2013-07-11
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによるHAI-1切断は細胞運動・浸潤に係るセリンプロテアーゼを活性化する2012
- Author(s)
  佐藤博, 滝野隆久
- Organizer
  第21回日本がん転移学会学術総会
- Place of Presentation
  オリエンタルホテル広島(広島県)
- Year and Date
  2012-07-13
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによるN-カドヘリン接着制御2012
- Author(s)
  滝野隆久、堂本貴寛、佐藤博
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによる HAI－1切断は細胞運動・浸潤に係るセリンプロテアーゼを活性化する2012
- Author(s)
  佐藤博、滝野隆久
- Organizer
  第21回日本がん転移学会学術総会
- Place of Presentation
  オリエントホテル広島（広島県）
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによるN-カドヘリン接着の制御2012
- Author(s)
  滝野隆久、堂本貴寛、佐藤博
- Organizer
  第21回日本がん転移学会学術総会
- Place of Presentation
  オリエントホテル広島（広島県）
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] HAI－1分解を介するセリンプロテアーゼ系の活性化は腫瘍細胞の遊走と浸潤能を亢進する2012
- Author(s)
  堂本貴寛、滝野隆久、源利成、佐藤博
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] HAI-1分解を介するセリンプロテアーゼ系の活性化は腫瘍細胞の遊走と浸潤能を亢進する2012
- Author(s)
  堂本貴寛, 滝野隆久, 源利成, 佐藤博
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによるN-カドヘリン接着の制御2012
- Author(s)
  滝野隆久, 堂本貴寛, 佐藤博
- Organizer
  第21回日本がん転移学会学術総会
- Place of Presentation
  オリエンタルホテル広島(広島県)
- Year and Date
  2012-07-13
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによるN-カドヘリン接着制御2012
- Author(s)
  滝野隆久, 堂本貴寛, 佐藤博
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] Cleavage of KIM-1 by MT1-MMP2011
- Author(s)
  Luyang Guo, Takahiro Domoto, Takahisa Takino, Hiroshi Sato.
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(石川県)
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMP activates matriptase through the cleavage of its inhibitor HAI-12011
- Author(s)
  堂本貴寛、滝野隆久、佐藤博
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] Glycogen synthase kinase (GSK) 3βは膠芽腫の浸潤を促進する2011
- Author(s)
  近野祐里, 中田光俊, 廣瀬まゆみ, 北野綾子, 宮下勝吉, 藤沢弘範, 林裕, 滝野隆久, 佐藤博, 崔吉道, 宮本謙一, 川上和之, 源利成
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによる免疫グロブリンファミリー膜タンパクKIM-1の切断2011
- Author(s)
  Guo Luyang、滝野隆久、佐藤博
- Organizer
  第20回日本がん転移学会総会
- Place of Presentation
  アクトシティ浜松(静岡県)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによるファイブロネクチンの重合と集積抑制2011
- Author(s)
  滝野隆久, 堂本貴寛, 佐藤博
- Organizer
  第20回日本がん転移学会学術総会
- Place of Presentation
  アクトシティ浜松(静岡県)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによるHAI-1切断を介したセリンプロテアーゼ系の制御2011
- Author(s)
  堂本貴寛, 滝野隆久, 佐藤博
- Organizer
  第20回日本がん転移学会学術総会
- Place of Presentation
  アクトシティ浜松(静岡県)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMP regulates fibronectin assembly2011
- Author(s)
  滝野隆久
- Organizer
  第70回　日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] Deregulated glycogen synthase kinase(GSK) 3υparticipates in invasion of glioblastoma2011
- Author(s)
  近野祐里、中田光俊、滝野隆久、佐藤博, 他10名
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMP regulates fibronectin assembly2011
- Author(s)
  滝野隆久、堂本貴寛、佐藤博
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによるフィブロネクチンの重合と集積抑制2011
- Author(s)
  滝野隆久
- Organizer
  第20回　日本がん転移学会学術集会
- Place of Presentation
  アクトシティ浜松（静岡県）
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPはHAI-1を切断することでMatriptaseを活性化する2011
- Author(s)
  堂本貴寛, 滝野隆久, 佐藤博
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23590356
[Presentation] MT1-MMPによるフィブロネクチンの重合と集積抑制2011
- Author(s)
  滝野隆久、堂本貴寛、佐藤博
- Organizer
  第20回日本がん転移学会総会
- Place of Presentation
  アクトシティ浜松(静岡県)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによるHAI-1切断を介したセリンプロテアーゼ系の制御2011
- Author(s)
  堂本貴寛、滝野隆久、佐藤博
- Organizer
  第20回日本がん転移学会総会
- Place of Presentation
  アクトシティー浜松(静岡県)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによる細胞増殖誘導機構2010
- Author(s)
  長尾亮太、滝野隆久、佐藤博
- Organizer
  第19回日本がん転移学会総会
- Place of Presentation
  金沢市文化ホール(石川県)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] Gi24はMT1-MMPを介したMMP-2活性化を促進することによりがん細胞浸潤を亢進する2010
- Author(s)
  佐藤博、堂本貴寛、滝野隆久
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによるHAI-1の分解を介したセリンプロテアーゼ系の制御2010
- Author(s)
  堂本貴寛、滝野隆久、佐藤博
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPは3次元コラーゲン内でc-srcとPaxillinを介してERK活性化と細胞増殖を亢進する2010
- Author(s)
  滝野隆久、堂本貴寛、佐藤博
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPは3次元コラーゲンゲル内でc-Src1とPaxillinを介してERK活性化と細胞増殖を亢進する2010
- Author(s)
  滝野隆久, 他2名、1番目
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPは3次元コラーゲン内でc-srcとPaxillinを介してERK活性化と細胞増殖を亢進する2010
- Author(s)
  滝野隆久
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによるセリンプロテアーゼ系の制御2010
- Author(s)
  堂本貴寛、滝野隆久、佐藤博
- Organizer
  第19回日本がん転移学会総会
- Place of Presentation
  金沢市文化ホール(石川県)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPは3次元コラーゲンゲル内でc-Src1とPaxillinを介してERK活性化と細胞増殖を亢進する2010
- Author(s)
  滝野隆久、堂本貴寛、佐藤博
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド (兵庫県)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21390091
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20013017
[Presentation] MT1-MMPによる浸潤性増殖誘導2009
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20013017
[Presentation] MT1-MMPによる浸潤性細胞増殖誘導2009
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPはFAkとERKを介して細胞浸潤と増殖を誘導する2008
- Author(s)
  滝野隆久, 佐藤博
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPによるMMP-2活性化は転移を増強する(優秀演題賞)2008
- Author(s)
  西田有希、滝野隆久、佐藤博
- Organizer
  第17回日本がん転移学会総会
- Place of Presentation
  鹿児島
- Year and Date
  2008-07-24
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMPはFAkとERKを介して細胞浸潤と増殖を誘導する2008
- Author(s)
  滝野隆久、佐藤博
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20013017
[Presentation] MT1-MMPによる細胞外マトリックス再構築誘導2008
- Author(s)
  小澤晃正、滝野隆久、西田有希、佐藤博
- Organizer
  第17回日本がん転移学会
- Place of Presentation
  鹿児島
- Year and Date
  2008-07-25
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMPによる浸潤性増殖誘導2008
- Author(s)
  滝野隆久、小澤晃正、西田有希、佐藤博
- Organizer
  第17回日本がん転移学会学術集会
- Place of Presentation
  鹿児島サンロイヤルホテル(鹿児島県)
- Year and Date
  2008-07-24
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPによる浸潤性増殖誘導2008
- Author(s)
  滝野隆久、小澤晃正、西田有希、佐藤博
- Organizer
  第17回日本がん転移学会
- Place of Presentation
  鹿児島
- Year and Date
  2008-07-24
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMPによる浸潤性増殖誘導2008
- Author(s)
  滝野隆久 (他3名、1番目)
- Organizer
  日本がん転移学会
- Place of Presentation
  鹿児島
- Year and Date
  2008-07-25
- Data Source
  KAKENHI-PROJECT-20013017
[Presentation] MT1-MMP活性制御機構の解析シンポジウム2008
- Author(s)
  佐藤博、滝野隆久
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMPはERKを介して細胞増殖と浸潤を増強する2008
- Author(s)
  滝野隆久, 佐藤博
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMPによる浸潤性増殖誘導2008
- Author(s)
  滝野隆久, 他3名, 1番目
- Organizer
  日本がん転移学会
- Place of Presentation
  鹿児島
- Year and Date
  2008-07-25
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPはFAKとERKを介して細胞増殖と浸潤を増強する2008
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMPによる浸潤性増殖誘導2008
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2008-10-22
- Data Source
  KAKENHI-PROJECT-20590306
[Presentation] MT1-MMPによる浸潤性増殖誘導2008
- Author(s)
  滝野隆久, 佐藤博
- Organizer
  日本がん転移学会総会
- Place of Presentation
  鹿児島
- Year and Date
  2008-07-24
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] Roles of MT1- MMP at cell-matrix adhesions2007
- Author(s)
  Takino, T., Sato, H
- Organizer
  Biochemistry and Molecular Biology
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] Targeting dominant negative form of MT1- M/MMP to cell-matrix adhesion enhances its inhibitory effect on tumor invasion2007
- Author(s)
  Takino, T., Sato, H
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] 細胞接着斑におけるMT1-MMPの役割2007
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-06
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMP阻害変異体の細胞接着斑への標的は腫瘍細胞の浸潤抑制を増強する2007
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] 細胞接着斑におけるMT1-MMPの役割2007
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] MT1-MMP阻害変異体の細胞接着斑への標的は腫瘍細胞の浸潤抑制を増強する2007
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] MT1-MMP阻害変異体の細胞接着斑への標的は腫瘍細胞の浸潤抑制を増強する2007
- Author(s)
  滝野隆久、佐藤博
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] 細胞接着斑におけるMT1-MMPの役割2007
- Author(s)
  柘植尚志、滝野隆久、佐藤博
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMPによるGDF15切断の生理的意義の解析2007
- Author(s)
  佐藤博、遠藤良夫、滝野隆久
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] TIMP-2キメラタンパクによるMT1-MMPを介したMMP-2活性化の促進2007
- Author(s)
  内原嘉仁、滝野隆久、佐藤博
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] 人工的なMMP-2受容体を介したMT1-MMPによるMMP-2活性化2007
- Author(s)
  宮森久志、滝野隆久、佐藤博
- Organizer
  第16回日本がん転移学会総会
- Place of Presentation
  富山
- Year and Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] MT1-MMP阻害変異体の細胞接着斑への標的は腫瘍細胞の浸潤抑制を増強する2007
- Author(s)
  滝野隆久
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] グルココルチコイド受容体を介したMT1-MMP遺伝子発現抑制2007
- Author(s)
  佐藤博、宮森久志、滝野隆久
- Organizer
  第16回日本がん転移学会総会
- Place of Presentation
  富山
- Year and Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-19390084
[Presentation] 細胞接着斑におけるMT1-MMP阻害2006
- Author(s)
  滝野隆久、宮森久志、佐藤博
- Organizer
  第65回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] Membrane-type 1 matrix metallo Proteinase modulates focal adhesion stability and cell migration2006
- Author(s)
  Takino, T., Miyamori, H., Sato, H
- Organizer
  11th International Congress of Metastasis Research Society
- Place of Presentation
  Tokushima
- Year and Date
  2006-09-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] Inhibition of MT1-MMP at focal Adhesions2006
- Author(s)
  Takino, T., Miyamori, H., Sato, H
- Organizer
  65th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] Roles of membrane-type 1 matrix metalloproteinase in tumor invasion2006
- Author(s)
  Takino, T
- Organizer
  48th Annual Meeting of Japanese Association for Oral Biology
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration2006
- Author(s)
  T. Takino, H. Miyamori, H. Sato
- Organizer
  11th International Congress of Metastasis Research Society
- Place of Presentation
  Tokushima, Japan
- Year and Date
  2006-09-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] MT1-MMPによる細胞運動制御機構2006
- Author(s)
  滝野隆久
- Organizer
  第48回歯科基礎医学会総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590287
[Presentation] MT1-MMPによるファイブロネクチン重合制御
- Author(s)
  滝野隆久, 堂本貴寛, 佐藤博
- Data Source
  KAKENHI-PROJECT-23590356

1. SATO Hiroshi (00115239)

# of Collaborated Projects: 9 results

# of Collaborated Products: 39 results
2. NAKADA Mitsutoshi (20334774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. MIYAMORI Hisashi (30345631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Seiki Motoharu (10154634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Ninomiya Itasu (60345618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 原田志津子 (10218646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 金子周一 (60185923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 越川直彦 (70334282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 坂本毅治 (70511418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山下太郎 (90377432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宇都義浩 (20304553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 遠藤良夫 (30211783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 寺島農

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 鈴木健之

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 辻勉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

takino takahisa 滝野 隆久

Takino Takahisa 滝野 隆久

滝野 隆久 タキノ タカヒサ

TAKINO Takahisa 滝野 隆久

Research Projects

Research Products

Co-Researchers

Cross-talk between cancer cells and fibroblasts during cancer progression.Principal Investigator

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Development of a selective inhibitor against Na+/H+ exchange transporter 5 (NHE5), which is a target candidate molecule for gastrointestinal cancer.

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Analysis of MT1-MMP-dependent molecular pathways in the diversity and transformation of hepatocellular carcinoma

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A molecular mechanism that regulates extracellular matrix degradation and cell polarity in migrating cells.Principal Investigator

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Study on role of membrane-type matrix metalloproteinase-1 in tumor malignancy

Principal Investigator

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膜型マトリックスメタロプロテアーゼによる細胞運動極性 制御機構Principal Investigator

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Cell migration induced by alternation of extracellular matrix microenvironmentPrincipal Investigator

Principal Investigator

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Study on mechanism of tissue degradation by membrane-type matrix metalloproteinase

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Analysis of a molecular mechanism by which JNK-binding proteins regulate turnover of focal adhesions and formAnalysis of a molecular mechanism by which JNK-binding proteins regulate turnover of focal adhesions and formation of cell polarityPrincipal Investigator

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Functional analysis of matrix metalloproteinases associated with tissue destruction

Principal Investigator

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がん浸潤の細胞運動と細胞外マトリックス分解機構の解析Principal Investigator

Principal Investigator

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Review Section

Research Institution

Analysis of regulatory mechanism for cell polarity formation by JNK binding molecules during migrationPrincipal Investigator

Principal Investigator

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癌細胞浸潤における細胞運動とMT-MMPの協調的制御機構の解析Principal Investigator

takino takahisa 滝野隆久

Takino Takahisa 滝野隆久

滝野隆久タキノタカヒサ

TAKINO Takahisa 滝野隆久

膜型マトリックスメタロプロテアーゼによる細胞運動極性制御機構Principal Investigator

[Journal Article] m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF--induced epithelial-mesenchymal transition of lung cancer cells.2022