HORIKAWA Kentaro 堀川健太郎

Researcher Number	40322309
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012: 熊本大学, 医学部附属病院, 非常勤診療医師 2007 – 2008: 熊本大学, 大学院・医学薬学研究部, 助教 2003 – 2005: Kumamoto University, Faculty of Medical and Pharmaceutical Sciences, Research Associate, 大学院・医学薬学研究部, 助手 2000 – 2002: KUMAMOTO UNIVERSITY SCHOOL OF MEDICINE JYOSHU (SENIOR STUFF), 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology / Hematology Except Principal Investigator Hematology / Hematology / Biological Sciences
Keywords	Principal Investigator HPRT / PNH / aplastic anemia / 発作性夜間血色素尿症 / 再生不良性貧血 / myelodysplastic syndromes / mutant clone / marrow failure / 一酸化窒素 / 骨髄異形成症候 … More / MDS / 変異クローン / 造血不全 / mutation / 骨髄異形成症候群 / 発作性夜間血色素尿 / 遺伝子変異 / 遣伝子変異 / PIG-A遺伝子 / エピジェネティクス / X染色体 … More Except Principal Investigator 発作性夜間血色素尿症 / B / MICA / ULBP / HPRT / Paroxysmal nocturnal hemoglobinuria / HPRT遺伝子 / ナチュラルキラー細胞 / PNH / 骨髄細胞 / Tリンパ球 / 遺伝子変異 / GPI anchored proteins / stress-inducible protein / Natural killer cells / Bone marrow failure / ストレス誘導蛋白 / GPIアンカー蛋白 / ストレス蛋白 / 造血不全 / bone marrow cells / T cells / mutations / T細胞 / HPRT gene / Monosomy 7 / Genetic instability / Hemolytic anemia / マイクロサテライト / 造血幹細胞 / モノソミー7 / 遺伝子不安定性 / 溶血性貧血 / 発作性夜間ヘモグロゼン尿症 / NKG2D / 発作性夜間ヘモグロビン尿症 / 再生不良性貧血 / 骨髄不全症候群 Less

エピジェネティクス制御による不活化Ｘ染色体上のＰＩＧ－Ａ遺伝子発現誘導Principal Investigator
- Principal Investigator
  
  堀川健太郎
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Clinical significance of NKG2D ligands as a pathognomonic marker for immune-mediated marrow injury in bone marrow failure syndromes
- Principal Investigator
  
  KAWAGUCHI Tatsuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Molecular mechanism of immune-mediated marrow failure in paroxysmal nocturnal hemoglobinuria
- Principal Investigator
  
  KAWAGUCHI Tatsuya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Evolutional mechanism of mutant clones in aplastic anemia and related marrow-failure disordersPrincipal Investigator
- Principal Investigator
  
  HORIKAWA Kentaro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Molecular mechanism of emergence of clonal disorders in aplastic anemiaPrincipal Investigator
- Principal Investigator
  
  HORIKAWA Kentaro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
発作性夜間血色素尿症患者における白血病の好発の機序の解明
- Principal Investigator
  
  NAKAKUMA Hideki
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Molecular pathogenesis of paroxysmal nocturnal hemoglobinuria as a preleukemia
- Principal Investigator
  
  NAKAKUMA Hideki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
THE ETIOLOGY OF SOMATIC MUTATIONS IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
- Principal Investigator
  
  KAWAGUCHI Tatsuya
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KUMAMOTO UNIVERSITY

All 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] NKG2D-mediated immunity underlying paroxysmal nocturnal haemoglobinuria and related bone marrow failure syndromes2009
- Author(s)
  Hanaoka H, Nakakuma H, Horikawa K, Nagakura S, Tsuzuki Y, Shimanuki M, Kojima K, Yonemura Y and Kawaguchi K.
- Journal Title
  
  British Journal of Haematology (in press)
- Data Source
  KAKENHI-PROJECT-19591119
[Journal Article] 発作牲夜間血色素尿症(PNH)の病態、診断と治療.2007
- Author(s)
  中熊秀喜, 花岡伸佳, 堀川健太郎, 川口辰哉.
- Journal Title
  
  日本医事新報 4333
  
  Pages: 57-62
- Data Source
  KAKENHI-PROJECT-19591119
[Journal Article] 発作性夜間血色素尿症(PNH)の病態、診断と治療2007
- Author(s)
  中熊秀喜、花岡伸佳、堀川健太郎、川口辰哉
- Journal Title
  
  日本医事新報 No.4333
  
  Pages: 57-62
- NAID
  40015353485
- Data Source
  KAKENHI-PROJECT-19591119
[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP.2006
- Author(s)
  Hanaoka N, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakuma H.
- Journal Title
  
  Blood 107
  
  Pages: 1184-1191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590949
[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP2006
- Author(s)
  Hanaoka N, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakuma H
- Journal Title
  
  Blood 107
  
  Pages: 1184-1191
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590946
[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP2006
- Author(s)
  Hanaoka N, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakuma H
- Journal Title
  
  Blood 107
  
  Pages: 1184-1191
- Data Source
  KAKENHI-PROJECT-16590949
[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP.2006
- Author(s)
  Hanaoka N, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakuma H.
- Journal Title
  
  Blood 107
  
  Pages: 1184-1191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590946
[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBPs.2006
- Author(s)
  Nobuyoshi H, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakuma H
- Journal Title
  
  Blood 107
  
  Pages: 1184-1191
- Data Source
  KAKENHI-PROJECT-16590946
[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP2006
- Author(s)
  Hanaoka N, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakumia H
- Journal Title
  
  Blood 107
  
  Pages: 1184-1191
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590949
[Presentation] PNHや再生不良性貧血ではNKG2D介在性免疫による造血障害が発生する2008
- Author(s)
  中熊秀喜、花岡伸佳、川口辰哉、島貫栄弥、小島研介、米村雄士、堀川健太郎
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591119
[Presentation] NKG2D-mediated marrow injury in paroxysmal nocturnal hemoglobinura and its related disorders2007
- Author(s)
  Nobuyoshi Hanaoka, Tatsuya Kawaguchi, Kentaro Horikawa,Shoichi Nagakura, Sonoko Ishihara, Yasuchika Tsuzuki, Yuji Yonemura, Hideki Nakakuma
- Organizer
  49^<th> Annual Meeting of the American Society of Hematology
- Place of Presentation
  Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-19591119

1. KAWAGUCHI Tatsuya (50244116)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
2. NAKAKUMA Hideki (90207746)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results

HORIKAWA Kentaro 堀川 健太郎

Research Projects

Research Products

Co-Researchers

エピジェネティクス制御による不活化Ｘ染色体上のＰＩＧ－Ａ遺伝子発現誘導Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical significance of NKG2D ligands as a pathognomonic marker for immune-mediated marrow injury in bone marrow failure syndromes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of immune-mediated marrow failure in paroxysmal nocturnal hemoglobinuria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evolutional mechanism of mutant clones in aplastic anemia and related marrow-failure disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of emergence of clonal disorders in aplastic anemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

発作性夜間血色素尿症患者における白血病の好発の機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular pathogenesis of paroxysmal nocturnal hemoglobinuria as a preleukemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE ETIOLOGY OF SOMATIC MUTATIONS IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] NKG2D-mediated immunity underlying paroxysmal nocturnal haemoglobinuria and related bone marrow failure syndromes2009

Author(s)

Journal Title

Data Source

[Journal Article] 発作牲夜間血色素尿症(PNH)の病態、診断と治療.2007

Author(s)

Journal Title

Data Source

[Journal Article] 発作性夜間血色素尿症(PNH)の病態、診断と治療2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP2006

Author(s)

Journal Title

Data Source

[Journal Article] Immunoselection by natural killer cells of PIG-A mutant cells missing stress-inducible ULBP.2006

HORIKAWA Kentaro 堀川健太郎