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YASUDA TOMOHARU  保田 朋波流

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… Alternative Names

保田 朋波流  ヤスダ トモハル

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Researcher Number 40334429
Other IDs
Affiliation (Current) 2022: 広島大学, 医系科学研究科(医), 教授
Affiliation (based on the past Project Information) *help 2019 – 2021: 広島大学, 医系科学研究科(医), 教授
2017 – 2018: 九州大学, 生体防御医学研究所, 准教授
2009: 理研, 研究員
2008: The Institute of Physical and Chemical Research, 分化制御研究グループ, 研究員
2007: The Institute of Physical and Chemical Research, 分化制御研究グループ, 研究員
2006: 独立行政法人理化学研究所, 分化制御研究グループ, 研究員
2001 – 2004: 東京医科歯科大学, 難治疾患研究所, 助手
Review Section/Research Field
Principal Investigator
Immunology / Basic Section 49070:Immunology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
B細胞 / リンパ腫 / 免疫応答 / 細胞分裂 / 細胞老化 / 体細胞変異 / 抗体 / BLNK / アダプター分子 / BCR … More / B細胞分化 / 細胞 / Erk / 胚中心 / シグナル分子 / T細胞依存性抗原 / 抗体産生細胞 / 免疫学 / 癌 / 発現制御 / T細胞 / 免疫老化 / 免疫寿命 / クローン選択 / 老化 / 細胞寿命 / エピゲノム制御 / 細胞増殖 … More
Except Principal Investigator
シグナル伝達 / 蛋白質 / 造血細胞 / チロシンキナーゼ / 免疫学 / 増殖異常 / アダプター / 癌 / Ras-Erk / アダプター分子 / EBウイルス Less
  • Research Projects

    (8 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (6 People)
  •  Epigenetic regulation of lymphocyte cell division and oncogenesisPrincipal Investigator

    • Principal Investigator
      保田 朋波流
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Hiroshima University
  •  Whole-life tracing and cell-cell regulation in B cellsPrincipal Investigator

    • Principal Investigator
      YASUDA TOMOHARU
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Hiroshima University
  •  Regulation of lymphocyte cell division and oncogenesisPrincipal Investigator

    • Principal Investigator
      YASUDA TOMOHARU
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Hiroshima University
      Kyushu University
  •  Molecular mechanisms limiting cell division in cancer and immunityPrincipal Investigator

    • Principal Investigator
      保田 朋波流
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  T細胞依存性抗原に対するB細胞応答におけるErkの役割の解明Principal Investigator

    • Principal Investigator
      保田 朋波流
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  BCR下流のアダプター分子BLNKと会合する新規シグナル分子の機能解析Principal Investigator

    • Principal Investigator
      保田 朋波流
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  蛋白質チロシンリン酸化と癌細胞の増殖応答

    • Principal Investigator
      山梨 裕司
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  免疫シグナル伝達におけるrasGAP結合蛋白質Dok及びDok-2の機能解析

    • Principal Investigator
      山梨 裕司
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University

All 2021 2020 2019 2018 2017 2008 2007 2004

All Journal Article Presentation

  • [Journal Article] A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK82021

    • Author(s)
      Sakurai Tetsuya、Kukimoto-Niino Mutsuko、Kunimura Kazufumi、Yamane Nana、Sakata Daiji、Aihara Ryosuke、Yasuda Tomoharu、Yokoyama Shigeyuki、Shirouzu Mikako、Fukui Yoshinori、Uruno Takehito
    • Journal Title

      Life Science Alliance

      Volume: 4

    • DOI

      10.26508/lsa.202000873

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06575, KAKENHI-PROJECT-18H02669, KAKENHI-PROJECT-19K22538
  • [Journal Article] Pathologically Relevant Mouse Models for Epstein-Barr Virus-Associated B Cell Lymphoma2021

    • Author(s)
      Huang Shiyu、Yasuda Tomoharu
    • Journal Title

      Frontiers in Immunology

      Volume: 12

    • DOI

      10.3389/fimmu.2021.639844

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02669, KAKENHI-PROJECT-19K22538
  • [Journal Article] Generation and characterization of CD19-iCre mice as a tool for efficient and specific conditional gene targeting in B cells2021

    • Author(s)
      Yasuda T, Saito Y, Ono C, Kawata K, Baba A, Baba Y.
    • Journal Title

      Scientific Reports

      Volume: 11 Pages: 5524-5524

    • DOI

      10.1038/s41598-021-84786-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02626, KAKENHI-PROJECT-18H02669, KAKENHI-PROJECT-19K22537, KAKENHI-PROJECT-19K22538
  • [Journal Article] Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis2020

    • Author(s)
      Sommermann Thomas、Yasuda Tomoharu、Ronen Jonathan、Wirtz Tristan、Weber Timm、Sack Ulrike、Caeser Rebecca、Zhang Jingwei、Li Xun、Chu Van Trung、Jauch Anna、Unger Kristian、Hodson Daniel J.、Akalin Altuna、Rajewsky Klaus
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Pages: 14421-14432

    • DOI

      10.1073/pnas.1921139117

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02669, KAKENHI-PROJECT-19K22538
  • [Journal Article] Measuring Protein Synthesis during Cell Cycle by Azidohomoalanine (AHA) Labeling and Flow Cytometric Analysis.2019

    • Author(s)
      Imami, K., Yasuda T.
    • Journal Title

      Bio-protocol

      Volume: 9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Journal Article] Measuring Protein Synthesis during Cell Cycle by Azidohomoalanine (AHA) Labeling and Flow Cytometric Analysis2019

    • Author(s)
      Imami K, Yasuda T.
    • Journal Title

      BIO-PROTOCOL

      Volume: 1 Pages: 1-7

    • DOI

      10.21769/bioprotoc.3215

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22538, KAKENHI-PROJECT-18H02669, KAKENHI-PROJECT-18K14674
  • [Journal Article] Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during Mitosis.2018

    • Author(s)
      Imami Koshi、Milek Miha、Bogdanow Boris、Yasuda Tomoharu、Kastelic Nicolai、Zauber Henrik、Ishihama Yasushi、Landthaler Markus、Selbach Matthias
    • Journal Title

      Mol. Cell

      Volume: 72 Pages: 84-98

    • DOI

      10.1016/j.molcel.2018.08.019

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14674, KAKENHI-PROJECT-18H02669
  • [Journal Article] Erk Kinases link pre-BCR signaling to transcriptional events required for early B cell expansion.2008

    • Author(s)
      Yasuda, T., et. al.
    • Journal Title

      Immunity (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790348
  • [Journal Article] Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.2004

    • Author(s)
      Tomoharu Yasuda 他
    • Journal Title

      The Journal of Experimental Medicine 200

      Pages: 1681-1687

    • Data Source
      KAKENHI-PROJECT-14028021
  • [Presentation] B cell division in the heterogeneous pre-tumor microenvironment is required for lymphoma development2020

    • Author(s)
      Tomoharu Yasuda, Klaus Rajewsky
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] 抗原受容体と免疫寿命のコントロール2020

    • Author(s)
      保田朋波流
    • Organizer
      広島市医師会 第135回学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] B cell division in the heterogeneous pre-tumor microenvironment is required for lymphoma development2020

    • Author(s)
      Tomoharu Yasuda, Klaus Rajewsky
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] 抗原受容体と免疫細胞の維持機構2020

    • Author(s)
      保田朋波流
    • Organizer
      第一三共 消化器疾患セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] 抗原受容体と免疫寿命のコントロール2020

    • Author(s)
      保田朋波流
    • Organizer
      広島市医師会 第135回学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] 抗原受容体と免疫細胞の維持機構2020

    • Author(s)
      保田朋波流
    • Organizer
      第一三共 消化器疾患セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] 抗原受容体シグナルとB細胞寿命2019

    • Author(s)
      保田朋波流
    • Organizer
      第46回 広島大学健康長寿研究拠点HiHAセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] 広島市 抗原受容体とB細胞寿命2019

    • Author(s)
      保田朋波流
    • Organizer
      第65回 広島大学第二外科同門研修会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] EBV-LMP1による宿主抗原性転換と細胞傷害性T細胞分化2019

    • Author(s)
      保田朋波流
    • Organizer
      第1回 感染に起因する腫瘍の共同研究セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] EBウイルスとヒト免疫系の共生/共進化2019

    • Author(s)
      保田朋波流
    • Organizer
      中国四国ウイルス研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] EBV-LMP1による宿主抗原性転換と細胞傷害性T細胞分化2019

    • Author(s)
      保田朋波流
    • Organizer
      第1回 感染に起因する腫瘍の共同研究セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] EBウイルスとヒト免疫系の共生/共進化2019

    • Author(s)
      保田朋波流
    • Organizer
      広島免疫学リサーチセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] 抗原受容体とB細胞寿命2019

    • Author(s)
      保田朋波流
    • Organizer
      第65回 広島大学第二外科同門研修会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] EBウイルスとヒト免疫系の共生/共進化2019

    • Author(s)
      保田朋波流
    • Organizer
      中国四国ウイルス研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] EBウイルスとヒト免疫系の共生/共進化2019

    • Author(s)
      保田朋波流
    • Organizer
      広島免疫学リサーチセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] 抗原受容体シグナルとB細胞寿命2019

    • Author(s)
      保田朋波流
    • Organizer
      第46回 広島大学健康長寿研究拠点HiHAセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22538
  • [Presentation] Active B cell division on plasma cell niche is required for lymphoma development.2018

    • Author(s)
      Yasuda, T., Baba, Y., and Rajewsky, K.
    • Organizer
      The 13th International Symposium of the Institute Network for Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02669
  • [Presentation] Epstein-BarrウイルスによるB細胞リンパ腫発症とその免疫監視機構2017

    • Author(s)
      保田朋波流
    • Organizer
      第21回生物機能研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06937
  • [Presentation] Requirement for Erk1 and Erk2 MAP kinases in the early Bcell development2007

    • Author(s)
      Yasuda, T.
    • Organizer
      日本免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-20
    • Data Source
      KAKENHI-PROJECT-18790348
  • 1.  山梨 裕司 (40202387)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  樋口 理 (50361720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  白形 正樹 (70251551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  BABA Yoshihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  柊元 睦子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  今見 考志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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