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SAWAI Hirozumi  沢井 博純

ORCIDConnect your ORCID iD *help
Researcher Number 40336681
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2008: 名古屋市立大学, 大学院・医学研究科, 准教授
2007: 名古屋市立大学, 大学院・医学研究科, 講師
2006: Nagoya City University, Graduate School of Medical Sciences, Assistant professor, 大学院医学研究科, 講師
2002 – 2004: Nagoya City University, Graduate School of Medical Sciences, Rsearch Associate, 大学院・医学研究科, 助手
2003: Nagoya City University, Graduate School of Medical Sciences, Research Associate, 大学院・医科学研究科, 助手
2001: 名古屋市立大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Digestive surgery
Except Principal Investigator
Digestive surgery / Digestive surgery
Keywords
Principal Investigator
インテグリン / 予後診断 / Interleukin-1α / 接着分子 / 膵癌
Except Principal Investigator
GDNF / 膵癌 / integrin / インテグリン / RET … More / pancreatic cancer / 神経浸潤 / NF-κB / Pancreatic / 肝転移 / IL-1α / adhesion molecule / transcription factor / 接着因子 / 転写因子 / NF-kappaB / interleukin-lalpha / neurotrophic factor / integtin / 神経栄養因子 / invasion / NF-KappaB / 膵臓癌 / colon cancer / adhesion molecules / liver metastasis / irradiation / sialyl Lewis^x antibody / sialyl Lewis^a antibody / preonerative radiotherany / 臨床応用 / 大腸癌 / 細胞接着分子 / 放射線照射 / シアリルルイスx抗原 / シアリルルイスa抗原 / 術前放射線療法 / GFRalpha-1 / neural invasion / GFR21 / GFRalpha1 / GFR-alpha1 / Tyrosine kinase / Integrin / Nerve invasion / チロシンキナーゼ / サイトカン / 癌・間質相互作用 / サイトカイン / 血管新生 / リンパ管新生 / 膵癌細胞株 / NFκB Less
  • Research Projects

    (9 results)
  • Research Products

    (102 results)
  • Co-Researchers

    (11 People)
  •  The study for angiogenesis focused on the cell-stromal interaction in pancreatic cancer

    • Principal Investigator
      TAKAHASHI Hiroki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  Clarification of control mechanisms for lever metastasis and nerve invasion in pancreatic cancer

    • Principal Investigator
      TAKAHASHI Hiroki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  Clarification of control mechanisms for metastasis/invasion in pancreatic cancer

    • Principal Investigator
      MANABE Tadao
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  Biological Effect of Irradiation on Adhesion Molecules in Human Colon Cancer Cells and Application to Clinical Medicine

    • Principal Investigator
      SATO Mikinori
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  Invasive and metastatic mechanisms of pancreatic cancer cells: the role of Glial Cell Line-Derived Neurotrophic Factor (GDNF), integrins, and NF-KappaB

    • Principal Investigator
      FUNAHASHI Hitoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  IL-1αアンチセンス遺伝子導入を用いた膵癌転移機序の解明

    • Principal Investigator
      MANABE Tadao
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  膵癌の予後診断を目的とした炎症性サイトカインによる接着分子の制御機構の解明Principal Investigator

    • Principal Investigator
      沢井 博純
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  Clarification of Nerve Invasion System in Pancreatic Cancer

    • Principal Investigator
      MANABE Tadao
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University
  •  Invasion mechanism of Pancreatic cells : the relationship Glial cell line-derived neurotrophic factor and integrin

    • Principal Investigator
      TAKEYAMA Hiromitsu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya City University

All 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Interleukin-1α secreted by pancreatic cancer cells promotes angiogenesis and its therapeutic implications2009

    • Author(s)
      Matsuo Y, Sawai H, Ochi N, Yasuda A, Takahashi H, Funahashi H, Takeyama H, Guha S.
    • Journal Title

      J Surg Res (in press)

    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth2008

    • Author(s)
      Funahashi H, Satake M, Hasan S, Sawai H, Newman RA, Reber HA, Hines OJ, Eibl G.
    • Journal Title

      Pancreas 36

      Pages: 353-362

    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells2008

    • Author(s)
      Sawai H, Okada Y, Funahashi H, Takahashi H, Matsuo Y, Yasuda A, Ochi N, Takeyama H, Manabe T.
    • Journal Title

      J Surg Res 144

      Pages: 117-123

    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Basement membrane proteins play an important role in the in vasive processes of human pancreatic cancer cells.2008

    • Author(s)
      Sawai H
    • Journal Title

      J Surg Res 144

      Pages: 117-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells.2008

    • Author(s)
      Sawai H
    • Journal Title

      J Surg Res 144

      Pages: 117-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Interleukin-1α enhances angiogenesis and is associated with liver metastatic potential in human gastric cancer cell lines2008

    • Author(s)
      Ma J, Sawai H, Matsuo Y, Ochi N, Yasuda A, Takahashi H, Wakasugi T, Funahashi H, Sato M, Okada Y, Takeyama H, Manabe T.
    • Journal Title

      J Surg Res 148

      Pages: 197-204

    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] 【消化器癌浸潤・転移における間質・血管新生を探る】膵癌転移における接着分子の役割を探る2007

    • Author(s)
      沢井博純
    • Journal Title

      分子消化器病 4(1)

      Pages: 30-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Immunohistochemical analysis of interleukin-1 receptor type I and α_6 integrin subunit in advanced gastrointestinal stromal tumor of the rectum with liver metastasis2007

    • Author(s)
      Sawai, H
    • Journal Title

      Hepatogastroenterology 54(In press)

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells.2007

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Journal of Surgical Research 139, (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Immunohistochemical analysis of interleukin-1 receptor type I and a6 integrin subunit in advanced gastrointestinal stromal tumor of the rectum with liver metastasis2007

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Hepatogastroenterology 54, (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Synthetic serine protease inhibitor, gabexate mesilate, prevents nuclear factor-κB activation and increases TNF-α-mediated apoptosis in human pancreatic cancer cells2007

    • Author(s)
      Takahashi H, Funahashi H, Sawai H, Matsuo Y, Yamamoto M, Okada Y, Takeyama H, Manabe T.
    • Journal Title

      Dig Dis Sci 52

      Pages: 2646-2652

    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells2007

    • Author(s)
      Sawai, H
    • Journal Title

      Journal of Surgical Research 139 (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Immunohistochemical analysis of interleukin-1 receptor type I and α_6 integrin subunit in advanced gastrointestinal stromal tumor of the rectum with liver metastasis2007

    • Author(s)
      Sawai, H
    • Journal Title

      Hepatogastroenterology 54 (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Expression of α6 integrin subunit is associated with malignancy in gastric gastrointestinal stromal tumors2007

    • Author(s)
      Takeyama H, Funahashi H, Sawai H, Akamo Y, Yamamoto M, Takahashi H, Manabe T.
    • Journal Title

      Med Sci Monit 13

    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Antiproteases in preventing the invasive potential of pancreatic cancer cells2007

    • Author(s)
      Takahashi H, Sawai H, Funahashi H, Matsuo Y, Yasuda A, Ochi N, Sato M, Okada Y, Takeyama H.
    • Journal Title

      JOP 8

      Pages: 501-508

    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells2007

    • Author(s)
      Sawai, H
    • Journal Title

      Journal of Surgical Research 139(In press)

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] 膵癌転移における接着分子の役割を探る2007

    • Author(s)
      沢井博純、岡田祐二、高橋広城、松尾洋一、竹山廣光、真辺忠夫
    • Journal Title

      分子消化器病 4

      Pages: 30-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Journal Article] Immunohistochemical analysis of interleukin-1 receptor type I and a6 integrin subunit in advanced gastrointestinal stromal tumor of the rectum with liver metastasis2007

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Hepatogastroenterology 54, (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells.2007

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Journal of Surgical Research 139, (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Immunohistochemical analysis of interleukin-1 receptor type I and α_6 integrin subunit in advanced gastrointestinal stromal tumor of the rectum with liver metastasis2007

    • Author(s)
      Sawai, H
    • Journal Title

      Hepatogastroenterology 54 (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells2007

    • Author(s)
      Sawai, H
    • Journal Title

      Journal of Surgical Research 139 (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Combined gemcitabine and alpha-interferon therapy for pancreatic cancer : Report of a case.2006

    • Author(s)
      Sawai, H
    • Journal Title

      Dig Dis Sci 51・3(in press)

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Clinicopathological and immunohistochemical analysis of malignant features in mucinous cystic tumors of the pancreas.2006

    • Author(s)
      Sawai, H
    • Journal Title

      Hepatogastroenterology 53・68

      Pages: 286-290

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Activation of peroxisome proliferator-activated receptor-y decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Molecular Cancer Research 4

      Pages: 159-167

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-1α a-induced progressive behavior of pancreatic cancer and poor patient survival2006

    • Author(s)
      Sawai, H
    • Journal Title

      Oncogene 25

      Pages: 3237-3246

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Activation of peroxisome proliferator-activated receptor-γ decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system2006

    • Author(s)
      Sawai, H
    • Journal Title

      Molecular Cancer Research 4

      Pages: 159-167

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Interleukin-1α enhances the aggressive behavior of pancreatic cancer cells by regulating the α_6β_1-integrin and urokinase plasminogen activator receptor expression2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      BMC Cell Biology 7.8(1-13)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Interleukin-la enhances the aggressive behavior of pancreatic cancer cells by regulating the α6β1-integrin and urokinase plasminogen activator receptor expression2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      BMC Cell Biology 7-8(1-13)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-1alpha-induced progressive behavior of pancreatic cancer and poor patient survival.2006

    • Author(s)
      Sawai, H
    • Journal Title

      Oncogene 25(in press)

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Interleukin-lα enhances the aggressive behavior of pancreatic cancer cells by regulating the α_6β_1-integrin and urokinase plasminogen activator receptor expression2006

    • Author(s)
      Sawai, H
    • Journal Title

      BMC Cell Biology 7・8

      Pages: 1-13

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Interleukin-lα enhances the aggressive behavior of pancreatic cancer cells by regulating the α_6β_1-integrin and urokinase plasminogen activator receptor expression2006

    • Author(s)
      Sawai, H
    • Journal Title

      BMC Cell Biology 7・8

      Pages: 1-13

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Clinicopathological and immunohistochemical analysis of malignant features in mucinous cystic tumors of the pancreas2006

    • Author(s)
      Sawai, H
    • Journal Title

      Hepatogastroenterology 53

      Pages: 286-290

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-la-induced progressive behavior of pancreatic cancer and poor patient survival2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Oncogene 25

      Pages: 3237-3246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Combined gemcitabine and alpha-interferon therapy for pancreatic cancer : Report of a case2006

    • Author(s)
      Sawai, H
    • Journal Title

      Digestive Diseases and Sciences 51

      Pages: 1285-1289

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Combined gemcitabine and alpha-interferon therapy for pancreatic cancer : Report of a case2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Digestive Diseases and Sciences 51

      Pages: 1285-1289

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Combined gemcitabine and alpha-interferon therapy for pancreatic cancer : Report of a case2006

    • Author(s)
      Sawai, H
    • Journal Title

      Digestive Diseases and Sciences 51

      Pages: 1285-1289

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-la-induced progressive behavior of pancreatic cancer and poor patient survival2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Oncogene 25

      Pages: 3237-3246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Clinicopathological and immunohistochemical analysis of malignant features in mucinous cystic tumors of the pancreas.2006

    • Author(s)
      Sawai, H
    • Journal Title

      Hepatogastroenterology 53・68

      Pages: 286-290

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Interleukin-1α enhances the aggressive behavior of pancreatic cancer cells by regulating the α6β1-integrin and urokinase plasminogen activator receptor expression.2006

    • Author(s)
      Sawai, H
    • Journal Title

      BMC Cell biology 7・8

      Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-1alpha-induced progressive behavior of pancreatic cancer and poor patient survival.2006

    • Author(s)
      Sawai, H
    • Journal Title

      BMC Cell Biology 7・8

      Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Interleukin-1α enhances the aggressive behavior of pancreatic cancer cells by regulating the α_6β_1-integrin and urokinase plasminogen activator receptor expression2006

    • Author(s)
      Sawai, H
    • Journal Title

      BMC Cell Biology 7・8

      Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Clinicopathological and immunohistochemical analysis of malignant features in mucinous cystic tumors of the pancreas2006

    • Author(s)
      Sawai, H
    • Journal Title

      Hepatogastroenterology 53

      Pages: 286-290

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Combined gemcitabine and alpha-interferon therapy for pancreatic cancer : Report of a case2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Digestive Diseases and Sciences 51

      Pages: 1285-1289

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-1α-induced progressive behavior of pancreatic cancer and poor patient survival2006

    • Author(s)
      Sawai, H
    • Journal Title

      Oncogene 25

      Pages: 3237-3246

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Clinicopathological and immunohistochemical analysis of malignant features in mucinous cystic tumors of the pancreas2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Hepatogastroenterology 53

      Pages: 286-290

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-1α-induced progressive behavior of pancreatic cancer and poor patient survival.2006

    • Author(s)
      Sawai, H
    • Journal Title

      Oncogene 25(in press)

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Clinicopathological and immunohistochemical analysis of malignant features in mucinous cystic tumors of the pancreas2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Hepatogastroenterology 53

      Pages: 286-290

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-1α-induced progressive behavior of pancreatic cancer and poor patient survival2006

    • Author(s)
      Sawai, H
    • Journal Title

      Oncogene 25

      Pages: 3237-3246

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Activation of peroxisome proliferator-activated receptor-γ decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system2006

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Molecular Cancer Research 4

      Pages: 159-167

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Activation of peroxisome proliferator-activated receptor-γ decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system2006

    • Author(s)
      Sawai, H
    • Journal Title

      Molecular Cancer Research 4

      Pages: 159-167

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Interleukin-1α enhances the aggressive behavior of pancreatic cancer cells by regulating the α_6β_1-integrin and urokinase plasminogen activator receptor expression2006

    • Author(s)
      Sawai, H
    • Journal Title

      BMC Cell Biology 7・8

      Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Integrin-linked kinase activity is associated with interleukin-lα-induced progressive behavior of pancreatic cancer and poor patient survival2006

    • Author(s)
      Sawai, H
    • Journal Title

      Oncogene 25

      Pages: 3237-3246

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Anaplastic carcinoma of the pancreas with squamous features : report of a case and immunohistochemical study2005

    • Author(s)
      Sawai, H
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling2005

    • Author(s)
      Sawai, H
    • Journal Title

      Cancer Research 65

      Pages: 11536-11544

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation2005

    • Author(s)
      Sawai, H
    • Journal Title

      Molecular Cancer 4・37

      Pages: 1-12

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Interleukin-la enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Anaplastic carcinoma of the pancreas with squamous features : report of a case and immunohistochemical study2005

    • Author(s)
      Sawai, H
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation.2005

    • Author(s)
      Sawai, H
    • Journal Title

      Molecular Cancer 4・37

      Pages: 1-12

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.2005

    • Author(s)
      Sawai, H
    • Journal Title

      Cancer Research 65・24

      Pages: 11536-11544

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Interleukin-la enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] The G691 S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Cancer research 65

      Pages: 11536-11544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Anaplastic carcinoma of the pancreas with squamous features : report of a case and immunohistochemical study2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Surgical treatment for relief of severe pain with chronic pancreatitis that is resistant to conservative treatment.2005

    • Author(s)
      Sawai H
    • Journal Title

      Hepato-Gastroenterology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Molecular Cancer 4-37

      Pages: 1-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Interleukin-1alpha enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells.2005

    • Author(s)
      Sawai, H
    • Journal Title

      Medical Science Monitor 11・10

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Cancer research 65

      Pages: 11536-11544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] The G691 S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.2005

    • Author(s)
      Sawai, H
    • Journal Title

      Cancer Research 65・24

      Pages: 11536-11544

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Anaplastic carcinoma of the pancreas with squamous features : report of a case and immunohistochemical study2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Expression of integrins in tumour tissue of a patient with cancer of the Vater's ampulla complicated by pancreas divisum2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Eur J Gastroenterol Hepatol 16

      Pages: 421-424

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling2005

    • Author(s)
      Sawai, H
    • Journal Title

      Cancer Research 65

      Pages: 11536-11544

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation.2005

    • Author(s)
      Sawai, H
    • Journal Title

      Molecular Cancer 4・37

      Pages: 1-12

    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation2005

    • Author(s)
      Sawai, H
    • Journal Title

      Molecular Cancer 4・37

      Pages: 1-12

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation2005

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Molecular Cancer 4

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Interleukin-1α enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells.2005

    • Author(s)
      Sawai, H
    • Journal Title

      Med Sci Monit 11・10

    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Interleukin-1α enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells2005

    • Author(s)
      Sawai, H
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591427
  • [Journal Article] Interleukin-1α enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells2005

    • Author(s)
      Sawai, H
    • Journal Title

      Medical Science Monitor 11

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Expression of integrins in tumour tissue of a patient with cancer of the Vater's ampulla complicated by pancreas divisum2004

    • Author(s)
      Sawai, H
    • Journal Title

      Eur J Gastroenterol Hepatol 16・4

      Pages: 421-424

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Immunohistochemical analysis of molecular biological factors in intraductal papillary-mucinous tumors and mucinous cystic tumors of pancreas2004

    • Author(s)
      Sawai, H
    • Journal Title

      Scand J Gastroenterol 39・11

      Pages: 1159-1165

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Expression of integrins in a patient of cancer tissues of the vater's ampulla complicated by pancreas divisum.2004

    • Author(s)
      Sawai H
    • Journal Title

      European Journal of Gastroenterology and Hepatology 16

      Pages: 421-424

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Tumor malignancy and gene expression analysis.2003

    • Author(s)
      Sawai H
    • Journal Title

      Surgery Frontier 10

      Pages: 33-38

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Immunohistochemical analysis of intraductal papillary- mucinous tumors of the pancreas.2003

    • Author(s)
      Sawai H
    • Journal Title

      Proceedings of the 38th Congress of the European Society for Surgical Research

      Pages: 181-184

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Pancreaticogastro anastomosis.2003

    • Author(s)
      Sawai H
    • Journal Title

      Surgical Therapy 88

      Pages: 655-660

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Expression and prognostic roles of integrins and interleukin-1 receptor type I in patients with ductal adenocarcinoma of the pancreas.2003

    • Author(s)
      Sawai H
    • Journal Title

      Digestive Diseases and Science 48

      Pages: 1241-1250

    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Tumor-forming pancreatitis diagnosed preoperatively as intraductal papillary-mucinous tumor : report of a case.2003

    • Author(s)
      Sawai H
    • Journal Title

      Pancreas 26

      Pages: 207-210

    • NAID

      10016164301

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Expression and prognostic roles of integrins and interleukin-1 receptor type I in patients with ductal adenocarcinoma of the pancreas.2003

    • Author(s)
      Sawai H
    • Journal Title

      Digestive Diseases and Sciences

      Pages: 1241-1250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Expression and prognostic roles of integrins and interleukin-1 receptor type I in patients with ductal adenocarcinoma of the pancreas.2003

    • Author(s)
      Sawai H
    • Journal Title

      Digestive Diseases and Sciences 48

      Pages: 1241-1250

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Immunohistochemical analysis of intraductal papillary-mucinous tumors of the pancreas.2003

    • Author(s)
      Sawai H
    • Journal Title

      Proceedings of the 38th Congress of the European Society for Surgical Research

      Pages: 181-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Surgical treatment for relief of severe pain with chronic pancreatitis that is resistant to conservative treatment.

    • Author(s)
      Sawai H
    • Journal Title

      Hepato-Gastroenterology in press

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591425
  • [Journal Article] Immunohistochemical analysis of molecular biological factors in intraductal papillary-mucinous tumors and mucinous cystic tumors of pancreas

    • Author(s)
      Hirozumi Sawai
    • Journal Title

      Scand J Gastroenterol 39

      Pages: 1159-1165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390383
  • [Journal Article] Surgical treatment for relief of severe pain with chronic pancreatitis that is resistant to conservative treatment.

    • Author(s)
      Sawai H
    • Journal Title

      Hepato-Gastroenterology (in press)

    • Data Source
      KAKENHI-PROJECT-15591425
  • [Presentation] N-6 多価不飽和脂肪酸(PUFA)の膵癌細胞増殖能、浸潤能への増強効果2008

    • Author(s)
      舟橋整、沢井博純、原賢康、安田顕、越智靖夫、坂本雅樹、高橋広城、松尾洋一、若杉健弘、高山悟、竹山廣光
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 膵漿液性嚢胞腺腫(solid type)の1例2008

    • Author(s)
      安田顕、沢井博純、越智靖夫、若杉健弘、舟橋整、竹山廣光
    • Organizer
      第63回日本消化器外科学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 治癒切除胃癌におけるnomogram を用いた予後の検討2008

    • Author(s)
      赤毛義実、竹山廣光、若杉健弘、舟橋整、沢井博純、佐藤幹則
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 膵癌由来VEGF-C によるリンパ管内皮細胞への影響2007

    • Author(s)
      越智靖夫、松尾洋一、沢井博純、岡田祐二、舟橋整、安田顕、高橋広城、佐藤幹則、真辺忠夫
    • Organizer
      第38回日本膵臓学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-06-29
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 膵癌リンパ管新生における腫瘍由来VEGF-Cの影響2007

    • Author(s)
      越智靖夫、松尾洋一、沢井博純、安田顕、舟橋整、高橋広城、佐藤幹則、竹山廣光
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 膵癌細胞の浸潤能に細胞外マトリックスが果たす役割2007

    • Author(s)
      沢井博純、越智靖夫、安田顕、高橋広城、松尾洋一、坂本雅樹、若杉健弘、舟橋整、佐藤幹則、赤毛義実、竹山廣光
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 大腸癌細胞の増殖におけるc-kit の関与について2007

    • Author(s)
      安田顕、高橋広城、松尾洋一、沢井博純、岡田祐二、佐藤幹則、竹山廣光、真辺忠夫
    • Organizer
      第107回日本外科学会定期学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-11
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 細胞外マトリックスが膵癌細胞の浸潤能に果たす役割2007

    • Author(s)
      沢井博純、岡田祐二、高橋広城、松尾洋一、安田顕、越智靖夫、舟橋整、佐藤幹則、竹山廣光、真辺忠夫
    • Organizer
      第19回日本肝胆膵外科学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-06-08
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 膵癌リンパ節転移に対する腫瘍由来VEGF-Cの影響2007

    • Author(s)
      越智靖夫、松尾洋一、岡田祐二、沢井博純、舟橋整、高橋広城、佐藤幹則、真辺忠夫
    • Organizer
      第107回日本外科学会定期学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-13
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 膵癌細胞の浸潤能に細胞外マトリックスがおよぼす影響2007

    • Author(s)
      沢井博純、岡田祐二、越智靖夫、安田顕、松尾洋一、舟橋整、竹山廣光、真辺忠夫
    • Organizer
      第38回日本膵臓学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-06-29
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 膵癌における膜結合型ケモカインの発現についての検討2007

    • Author(s)
      高橋広城、安田顕、越智靖夫、若杉健弘、高山悟、沢井博純、岡田祐二、赤毛義実、竹山廣光、真辺忠夫
    • Organizer
      第62回日本消化器外科学会定期学術総会
    • Place of Presentation
      東京
    • Year and Date
      2007-07-19
    • Data Source
      KAKENHI-PROJECT-19591596
  • [Presentation] 細胞外マトリックスが膵癌細胞の浸潤能に果たす役割2007

    • Author(s)
      沢井博純
    • Organizer
      第19回日本肝胆膵外科学会・学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2007-06-08
    • Data Source
      KAKENHI-PROJECT-19591596
  • 1.  MANABE Tadao (80127141)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  OKADA Yuji (10305550)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 11 results
  • 3.  YAMAMOTO Minoru (70347417)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  TAKEYAMA Hiromitsu (00216946)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 16 results
  • 5.  TANAKA Moritsugu (10227184)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TAKAHASHI Hiroki (30381792)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 7.  MATSUO Yoich (40381800)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 8.  SATO Mikinori (20305551)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  FUNAHASHI Hitoshi (10347411)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  赤毛 義実 (90264720)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TAKAYAMA Satoru (70381887)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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