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KOKUBO Yasuaki  小久保 安昭

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… Alternative Names

小久保 安昭  コクボ ヤスアキ

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Researcher Number 40343074
Other IDs
Affiliation (Current) 2025: 山形大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2024: 山形大学, 大学院医学系研究科, 准教授
2016 – 2022: 山形大学, 大学院医学系研究科, 准教授
2016: 山形大学, 医学系研究科, 准教授
2015: 山形大学, 医学(系)研究科(研究院), 准教授
2007: Yamagata University, 医学部, 助教
2006: 山形大学, 医学部, 講師
2004 – 2005: 山形大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Neurosurgery
Except Principal Investigator
Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related / Basic Section 90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Basic Section 90110:Biomedical engineering-related / Neurosurgery / Measurement engineering
Keywords
Principal Investigator
leukoaraiosis / 大脳白質 / glial progenitor / oligodendrocyte / 慢性脳虚血 / 脳組織酸素飽和度 / 脳神経外科手術 / 脳血管障害学 / 頭蓋内主幹動脈狭窄 / モヤモヤ病 … More / スクリーニング / RNF213 / もやもや病 / demyelination / 脱髄 / 認知機能低下 / 大脳白質病変 / ミエリン / 成熟オリゴデンドロサイト / オリゴデンドロサイト前駆細胞 / axon … More
Except Principal Investigator
拡散反射イメージング / 組織バイアビリティ / RGBカメラ / 組織分光学 / RGB画像 / 術中画像診断 / 脳組織バイアビリティ / RGBカラーカメラ / 光散乱特性 / 血流量 / バイアビリティ / 術中モニター / リアルタイムイメージング / 組織酸素飽和度 / 生体臓器 / 脳組織 / ゲノム解析 / 脳神経疾患 / ヘモグロビン / 脳組織障害 / 脳血流 / 脳機能イメージング / 脳局所酸素飽和度 Less
  • Research Projects

    (8 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (17 People)
  •  Development of a diagnostic imaging system for intraoperative multiscale brain viability

    • Principal Investigator
      西舘 泉
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90130:Medical systems-related
      Basic Section 90140:Medical technology assessment-related
      Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Development of brain tissue oxygen saturation monitoring system using video data during microsurgeryPrincipal Investigator

    • Principal Investigator
      小久保 安昭
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Yamagata University
  •  Development of intraoperative realtime diagnostic imaging technique for brain tissue viability by using RGB camera

    • Principal Investigator
      Nishidate Izumi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Elucidation of genetic and environmental factors for the onset of cerebrovascular disease due to mutation of the moyamoya disease susceptibility gene RNF213Principal Investigator

    • Principal Investigator
      Kokubo Yasuaki
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Yamagata University
  •  Study on intraoperative brain tissue oximetry imaging system using RGB camera

    • Principal Investigator
      NISHIDATE IZUMI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Measurement engineering
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Assembly of next-generation genomic cohort to enable research of the correlation with gene-environment factors for cardiovascular disease

    • Principal Investigator
      KAYAMA Takamasa
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurosurgery
    • Research Institution
      Yamagata University
  •  慢性脳虚血におけるオリゴデンドロサイトの動態、大脳白質病変発症抑制に関する研究Principal Investigator

    • Principal Investigator
      小久保 安昭
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Yamagata University
  •  脳虚血、大脳白質病変における神経軸索伸長阻害因子抑制の効果に関する研究Principal Investigator

    • Principal Investigator
      小久保 安昭
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Yamagata University

All 2023 2021 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] In vivo estimation of optical properties of rat liver using single-reflectance fiber probe during changing fraction of inspired oxygen2018

    • Author(s)
      Afrina Mustari, Takuya Kanie, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo, and Izumi Nishidate
    • Journal Title

      International Journal of Molecular Science

      Volume: 19 Issue: 2 Pages: 491-491

    • DOI

      10.3390/ijms19020491

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] マウス虚血性脳梗塞モデルの脳組織血行動態と光散乱特性のin vivo評価2023

    • Author(s)
      中村文乃,川内聡子,佐藤俊一,佐藤学,小久保安昭,西舘泉
    • Organizer
      レーザー学会学術講演会第43回年次大会
    • Data Source
      KAKENHI-PROJECT-20H04513
  • [Presentation] 総頚動脈結紮により誘発されたマウス脳血流の自発的低周波振動の解析2023

    • Author(s)
      渡部菜生,川内聡子,佐藤俊一,佐藤学,小久保安昭,西舘泉
    • Organizer
      レーザー学会学術講演会第43回年次大会
    • Data Source
      KAKENHI-PROJECT-20H04513
  • [Presentation] RGB-based Real-time Monitoring of Brain Tissue Viability During Neurosurgery2021

    • Author(s)
      Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      Symposium on Multimodal Medical Engineering (MME, 2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H04513
  • [Presentation] 術中リアルタイム脳組織酸素飽和度イメージングシステムに関する基礎研究2021

    • Author(s)
      高田智郁,中村文乃,渡部菜生,川内聡子,佐藤俊一,佐藤学,小久保安昭,西舘泉
    • Organizer
      Optics & Photonics Japan 2021
    • Data Source
      KAKENHI-PROJECT-20H04513
  • [Presentation] RGBカメラを用いた脳組織局所酸素飽和度のリアルタイムイメージング2021

    • Author(s)
      西舘 泉,加賀 祐紀,高田 知郁,佐藤 学,小久保 安昭
    • Organizer
      第68回応用物理学会春季学術講演会
    • Data Source
      KAKENHI-PROJECT-20H04513
  • [Presentation] 脳神経外科手術におけるRGBカメラによる術中リアルタイム脳組織酸素飽和度モニタリングシステムの開発2021

    • Author(s)
      佐藤 慎治, 小久保 安昭, 中村 和貴, 佐野 顕史, 五十嵐 晃平, 下川 友侑, 川並 香菜子, 板垣 寛, 西館 泉, 園田 順彦
    • Organizer
      第30回 脳神経外科手術と機器学会
    • Data Source
      KAKENHI-PROJECT-20H04513
  • [Presentation] In vivo imaging of cerebral hemodynamics and tissue scattering in rat brain using a surgical microscope camera system2018

    • Author(s)
      Izumi Nishidate, Takuya Kanie, Afrina Mustari, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      Photonics West BiOS 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] RNF213変異からみたもやもや病及び頭蓋内主幹動脈狭窄症の臨床像と スクリーニング検査としての意義2018

    • Author(s)
      小久保安昭
    • Organizer
      第44回日本脳卒中学会
    • Data Source
      KAKENHI-PROJECT-17K10818
  • [Presentation] 手術用顕微鏡一体型脳組織バイアビリティイメージングシステムのための基礎的研究2017

    • Author(s)
      蟹江卓矢,Mustari Afrina, 西舘泉,川内聡子,佐藤俊一,佐藤学,小久保安昭
    • Organizer
      日本光学会年次学術講演会Optics & Photonics Japan 2017
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] 術中脳組織バイアビリティイメージングシステムのための基礎的研究2017

    • Author(s)
      蟹江卓矢,西舘泉,Mustari Afrina, 川内聡子,佐藤俊一,佐藤学,小久保安昭
    • Organizer
      電気学会 光・量子デバイス研究会 バイオメディカルフォトニクス応用
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] Evaluation of spontaneous low-frequency oscillations in cerebral hemodynamics with time-series red-green-blue images2017

    • Author(s)
      Izumi Nishidate, Afrina Mustari, Naoki Nakamura, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      SPIE Photonics West BiOS 2017
    • Place of Presentation
      he Moscone Center San Francisco, California, USA
    • Year and Date
      2017-01-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] Assessment of cerebral hemodynamics and tissue morphology of rat brain during cortical spreading depolarization with a digital RGB camera2017

    • Author(s)
      Afrina Mustari, Takuya Kanie, Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      OSJ-OSA Joint Symposia 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] RNF213変異陽性のもやもや病及び頭蓋内主幹動脈狭窄症例の特徴2017

    • Author(s)
      小久保安昭
    • Organizer
      日本脳卒中学会
    • Data Source
      KAKENHI-PROJECT-17K10818
  • [Presentation] In vivo imaging of tissue scattering parameter and cerebral hemodynamics in rat brain with a digital red-green-blue camera2017

    • Author(s)
      Izumi Nishidate, Afrina Mustari, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      SPIE Photonics West BiOS 2017
    • Place of Presentation
      The Moscone Center San Francisco, California, USA
    • Year and Date
      2017-01-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] In vivo imaging of Spontaneous Low-frequency Oscillations in Cerebral hemodynamics with a digital red-green-blue Camera2017

    • Author(s)
      A. Mustari, N. Nakamura, I. Nishidate, S. Kawauchi, S. Sato, M. Sato, Y. Kokubo
    • Organizer
      Biomedical Imaging and Sensing Conference (BISC’17)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] 時系列拡散反射光画像に基づくラット脳局所血液量の自発的低周波変動の評価2017

    • Author(s)
      西舘泉,中村直樹,Afrina Mustari,川内聡子,佐藤俊一,佐藤学,小久保安昭
    • Organizer
      第6回ニューロフォトニクス研究会(レーザー学会第510回研究会)
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] In vivo evaluation of cortical hemodynamics and depolarization in rat brain with a digital red-green-blue camera2017

    • Author(s)
      Izumi Nishidate, Afrina Mustari, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      RIEC International Workshop on Biomedical Optics 2017
    • Place of Presentation
      Tohoku University, Department of Electrical, Information and Physics Engineering, Miyagi, Japan
    • Year and Date
      2017-03-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] In vivo imaging of cerebral hemodynamics and regional oxygen saturation in rats with a digital red-green-blue camera2016

    • Author(s)
      Izumi Nishidate, Yoshika Harasaki, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      SPIE Photonics West BiOS 2016
    • Place of Presentation
      The Moscone Center San Francisco, California, USA
    • Year and Date
      2016-02-13
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] 光伝搬数値シミュレーションを用いたカラー画像解析に基づく脳機能イメージング2016

    • Author(s)
      西舘泉,Afrina Mustari,原崎芳加,川内聡子,佐藤俊一,佐藤学,小久保安昭
    • Organizer
      レーザー学会第493回研究会 「光・レーザーの医学・医療応用」
    • Place of Presentation
      東北大学工学部電子・情報システム応物系1号館2階大会議室
    • Year and Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] Visualization of spontaneous low-frequency oscillations in cerebral hemodynamics with a digital red-green-blue camera2016

    • Author(s)
      Mustari Afrina, Naoki Nakamura, Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, and Yasuaki Kokubo
    • Organizer
      レーザー学会第498回研究会「第5回ニューロフォトニクス研究会」
    • Place of Presentation
      東京農工大学 生物システム応用科学府 第1講義室
    • Year and Date
      2016-11-19
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] 拡散反射分光法に基づくカラー画像解析を用いたin vivo脳組織バイアビリティの評価2016

    • Author(s)
      西舘泉,Afrina Mustari,川内聡子,佐藤俊一,佐藤学,小久保安昭
    • Organizer
      第13回バイオオプティクス研究会
    • Place of Presentation
      前橋テルサ、前橋工科大学
    • Year and Date
      2016-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] RGB画像に基づくラット大脳皮質の局所酸素飽和度評価2016

    • Author(s)
      原崎芳加, Mustari Afrina, 西舘泉, 川内聡子, 佐藤俊一, 佐藤学, 小久保安昭
    • Organizer
      光・量子デバイス研究会Technical Meeting on “Optical and Quantum Devices”, IEE Japan
    • Place of Presentation
      東北大学 東京分室
    • Year and Date
      2016-09-26
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] Imaging of regional cerebral oxygen saturation of rat with a digital red-green-blue camera2016

    • Author(s)
      Yoshika Harasaki, Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo
    • Organizer
      Biomedical Imaging and Sensing Conference 2016
    • Place of Presentation
      Pacifico Yokohama, Japan
    • Year and Date
      2016-05-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] RGBカメラを用いたラット脳の血行動態イメージング2015

    • Author(s)
      原崎芳加、西舘泉、川内聡子、佐藤俊一、佐藤学、小久保安昭
    • Organizer
      Optics&Photonics Japan 2015
    • Place of Presentation
      筑波大学東京キャンパス文京校舎
    • Year and Date
      2015-10-28
    • Data Source
      KAKENHI-PROJECT-15K06105
  • [Presentation] RGBイメージセンサーを用いたラット脳組織の局所酸素飽和度イメージング2015

    • Author(s)
      原崎芳加、西舘泉、川内聡子、佐藤俊一、佐藤学、小久保安昭
    • Organizer
      Medical Optics & Spectroscopy 2015
    • Place of Presentation
      ホテルグランヒル市ヶ谷
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-15K06105
  • 1.  NISHIDATE IZUMI (70375319)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 23 results
  • 2.  KAYAMA Takamasa (50142972)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  YAMASHITA Hidetoshi (90158163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KUBOTA Isao (30161673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NEMOTO Kenji (10208291)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SATO Shinya (00302290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MURAKAMI Masayasu (00577760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TOGASHI Hitoshi (60192209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  FUKAO Akira (80156736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NAKAJIMA Osamu (80312841)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KITANAKA Chihumi (70260320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  UENO Yoshiyuki (70282126)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SUZUKI Kyoko (20271934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KATO Takeo (90194828)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KAWASAKI Ryo (70301067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Narimatsu Hiroto (50524419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  川内 聡子 (20506505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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