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Higashi Yukihito  東 幸仁

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… Alternative Names

HIGASHI Yukihito  東 幸仁

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Researcher Number 40346490
Other IDs
Affiliation (Current) 2025: 広島大学, 原爆放射線医科学研究所, 教授
Affiliation (based on the past Project Information) *help 2011 – 2024: 広島大学, 原爆放射線医科学研究所, 教授
2009 – 2010: 広島大学, 医歯(薬)学総合研究科, 准教授
2009 – 2010: Hiroshima University, 医歯薬学総合研究科, 准教授
2007: Hiroshima University, Graduate School of Biomedical Sciences, Associate Professor
2006: 広島大学, 大学院医歯薬学総合研究科, 助教授 … More
2005: 広島大学, 病院・講師
2005: 広島大学, 大学院医歯薬学総合研究科, 講師
2004: Hiroshima University, Graduate School of Biomedical Science, Assistant Professor, 大学院・医歯薬学総合研究科, 講師
2003: 広島大学, 大学院・医歯薬学総合研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Basic Section 53020:Cardiology-related / Emergency medicine
Except Principal Investigator
Pathobiological dentistry/Dental radiology / Cardiovascular medicine / Basic Section 53040:Nephrology-related / Basic Section 53020:Cardiology-related / Basic Section 57060:Surgical dentistry-related / Kidney internal medicine / Orthopaedic surgery / Laboratory medicine / Circulatory organs internal medicine
Keywords
Principal Investigator
血管内皮機能 / Mesenchymal stem cell / Angiogenesis / ビュルガー病 / 閉塞性動脈硬化症 / 骨髄間葉系幹細胞 / 血管新生 / 細胞バンク / 新規血管内皮機能改善薬 / ヒト血管内皮機能 … More / 内皮型一酸化窒素合成酵素 / 新規レジスチン様分子 / Buerger's disease / Peripheral arterial disease / Endotbelial function / Cell store / Auto cell culture machine / Endothelial progenitor cell / Burger disease / Arteriosclerotic obliterance / Endothelial function / Autologous bone-marrow mononuclear cell implantation / 細胞自動培養増殖装置 / 細胞自動培養装置 / 血管内皮前駆細胞 / 自家骨骨髄細胞移植 / 再生療法 / 再生医療 / 緊急被ばく医療 / 血管状態測定装置 / 動脈硬化 / バイオマーカー / 血管弾性 … More
Except Principal Investigator
血管内皮機能 / スクリーニング / 骨折 / パノラマエックス線写真 / 骨粗鬆症 / 心血管障害 / パノラマX線写真 / 時計遺伝子 / ROCK / 皮質骨形態 / 脆弱性骨折 / 糖尿病性腎症 / 抗炎症作用 / 線維化 / 心不全 / ミトコンドリア / 高血圧 / 糖尿病 / DEC1 / 動脈硬化 / 国際情報交流 米国 / 脳梗塞 / 総頸動脈石灰化 / マクロファージ / microRNA / TSG-6 / 細胞外小胞 / 間葉系幹細胞 / 人工知能 / B cell lymphoma-2 / 急性腎障害 / P53 / 低酸素 / survivin / p53 / 炎症細胞浸潤 / 生存率 / 心筋梗塞 / アポトーシス / 下肢虚血 / 血管新生 / 下肢閉塞性動脈硬化症 / 閉塞性動脈硬化症 / 自家移植 / 心筋再生 / 骨質劣化 / 骨質 / 生活関連病 / 老化 / 血管障害 / ストレス誘導性細胞老化 / 再生医学 / 運動器外傷学 / 筋・神経病学 / 腎線維化 / 腎硬化症 / 超音波療法 / パノラマエックス線謝写真 / 歯科 / 歯槽骨吸収 / 頸動脈石灰化 / 骨梁解析 / 血管 / アルデヒド脱水素酵素 / iPS細胞 / 酸化ストレス / 飲酒 / 心筋症 / 心房細動 / アルデヒド脱水酸化酵素 / inflammation / artery / hypertension / shear stress / platelets / reactive hyperemia / endothelium / atherosclerosis / 炎症反応 / 頚動脈 / ずり応力 / 血小板 / 反応性充血 / 血管内皮 / 米国 / 国際情報交流 / 概日リズム / Na-K-ATPase / 日内変動 / CLOCK / 血圧 / 頚部石灰化 / 大腿骨 / オッズ比 / 総頚動脈石灰化所見 / パノラマX線写真 / 顎骨 / 臨床 / 発現制御 / 循環器・高血圧 / シグナル伝達 / トランスレーショナルリサーチ / eNOS / 血管機能 / エックス線写真 / 梗塞性心臓血管病変 / MRI / かくれ脳梗塞 / 予防医学 / 心臓血管疾患 / 梗塞 / 歯周病 / 口腔衛生 / プレチスモグラフィ / 脳血管障害 / 石灰化 / 総頸動脈 / CT / 歯科放射線学 / 歯学 / 自動支援 / 女性 / 閉経 Less
  • Research Projects

    (24 results)
  • Research Products

    (362 results)
  • Co-Researchers

    (51 People)
  •  Suppression of renal injury by extracellular vesicles from mesenchymal stem cells

    • Principal Investigator
      中島 歩
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      University of Yamanashi
  •  内皮型NO合成酵素制御および血管内皮機能調整における時計遺伝子DEC1の役割

    • Principal Investigator
      丸橋 達也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Hiroshima University
  •  画像指標と臨床所見を統合した脆弱性骨折リスク患者スクリーニングシステムの開発

    • Principal Investigator
      田口 明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Matsumoto Dental University
  •  elucidation of endothelial nitric oxide synthase regulation mechanism by a novel resistin-like molecule, relm beta, and its relationship to atherosclerosisPrincipal Investigator

    • Principal Investigator
      東 幸仁
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Hiroshima University
  •  Autologous Mitochondrial Transplantation Rescues Critical Limb Ischemia

    • Principal Investigator
      Kihara Yasuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Hiroshima University
  •  Effect of DEC1 on renal fibrosis and apoptosis induced by ischemia reperfusion injury

    • Principal Investigator
      Nakashima Ayumu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Hiroshima University
  •  Development of screening system for identifying individuals with lifestyle-related fragility fractures by oral and maxillofacial image indices

    • Principal Investigator
      Taguchi Akira
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Matsumoto Dental University
  •  Role of ROCK in stress-induced cellular senecesense on diabetes: from bench to bedside

    • Principal Investigator
      NOMA KENSUKE
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Hiroshima University
  •  Low-Intensity Pulsed Ultrasound Ameliorates Experimental Renal Fibrosis

    • Principal Investigator
      Nakashima Ayumu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Hiroshima University
  •  Mitochondrial ALDH2 Genotype and Heart Failure

    • Principal Investigator
      Kihara Yasuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Hiroshima University
  •  Construction of the new osteoporosis screening system which unified indices detected on oral and maxillofacial image

    • Principal Investigator
      Taguchi Akira
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Matsumoto Dental University
  •  Role of ROCK in diabetes-mediated cardiovascular disease: from bench to bedside

    • Principal Investigator
      NOMA KENSUKE
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Hiroshima University
  •  Transplantation of human adipose tissue-derived regenerative cells for peripheral nerve regeneration.

    • Principal Investigator
      YOKOTA Kazunori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Hiroshima University
  •  The role of clock genes in non-dipper hypertension

    • Principal Investigator
      Nakashima Ayumu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Hiroshima University
  •  Construction of medicine for radiation emergency system using iPS cell bankPrincipal Investigator

    • Principal Investigator
      Higashi Yukihito
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Hiroshima University
  •  Risk estimation of osteoporotic fracture and atherosclerosis by oral health indices on panoramic radiographs

    • Principal Investigator
      TAGUCHI Akira
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Matsumoto Dental University
  •  Role of ROCK activity in cardiovascular diseases: a translational research

    • Principal Investigator
      NOMA KENSUKE
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hiroshima University
  •  Development of Diagnostic System of Vascular Function for Assessment of AtherosclerosisPrincipal Investigator

    • Principal Investigator
      HIGASHI Yukihito
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hiroshima University
  •  Development of oral health-related indices for identifying individuals with increased risk of ischemic cardiovascular diseases

    • Principal Investigator
      TAGUCHI Akira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Matsumoto Dental University
  •  Therapeutic Angiogenesis with Autologous Mesenchymal Stem Cell in Patients with Peripheral Artery Diseases: Mesenchymal Stem Cell Storing SystemPrincipal Investigator

    • Principal Investigator
      HIGASHI Yukihito
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hiroshima University
  •  パノラマX線写真と血管内皮機能測定を併用する脳血管障害についての研究

    • Principal Investigator
      李 薫
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hiroshima University
  •  歯科用パノラマX線写真による心血管系疾患の早期スクリーニング支援システムの開発

    • Principal Investigator
      TAGUCHI Akira
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hiroshima University
  •  Systematization of Non-invasive Evaluation of Atherosclerosis in Clinical Laboratory Medicine

    • Principal Investigator
      OSHIMA Tetsuya
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Autologous Bone-marrow Mononuclear Cell Implantation in Patients with Peripheral Artery Diseases : Mesenchymal Stem Cell Acute Culture Method and Assessment of Endothelial Function in AngiogenesisPrincipal Investigator

    • Principal Investigator
      HIGASHI Yukihito
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hiroshima University

All 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent Other

  • [Book] Therapeutic Angiogenesis2017

    • Author(s)
      Yukihito Higashi、Toyoaki Murohara、Yasuki Kihara
    • Total Pages
      266
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Book] ICU看護実践ハンドブック2013

    • Author(s)
      野間玄督,東 幸仁
    • Total Pages
      4
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Book] 糖尿病と酸化ストレス2011

    • Author(s)
      野間玄督, 東幸仁
    • Total Pages
      5
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Era of biomarker-based disease risk management2023

    • Author(s)
      Higashi Y
    • Journal Title

      Hypertens Res

      Volume: 46 Issue: 4 Pages: 893-893

    • DOI

      10.1038/s41440-023-01187-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Association Between Endothelial Dysfunction and Left Ventricular Diastolic Stiffness ― Subanalysis of the Flow-Mediated Dilation Japan (FMD-J) Study ―2023

    • Author(s)
      Takei Y, Tomiyama H, Higashi Y, Yamashina A, Chikamori T.
    • Journal Title

      Circ J

      Volume: 87 Issue: 9 Pages: 1203-1211

    • DOI

      10.1253/circj.CJ-22-0810

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2023-08-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Current topic of vascular function in hypertension2023

    • Author(s)
      Maruhashi T, Higashi Y
    • Journal Title

      Hypertens Res

      Volume: 46 Issue: 3 Pages: 630-630

    • DOI

      10.1038/s41440-022-01147-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Therapeutic myogenesis induced by ultrasound exposure in a volumetric skeletal muscle loss injury model.2023

    • Author(s)
      Yusoff FM, Nakashima A, Kajikawa M, Maruhashi T, Kishimoto S, Higashi Y.
    • Journal Title

      Am J Sports Med

      Volume: 51 Issue: 13 Pages: 3554-3554

    • DOI

      10.1177/03635465231195850

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Impact of overnight 1 mg dexamethasone on vascular function in patients with nonfunctioning adrenal adenomas.2023

    • Author(s)
      Kishimoto S, Maruhashi T, Kajikawa M, Mizobuchi A, Yamaji T, Harada T, Nakano Y, Goto C, Yusoff FM, Nakashima A, Higashi Y.
    • Journal Title

      Sci Rep.

      Volume: 13 Issue: 1 Pages: 20975-20975

    • DOI

      10.1038/s41598-023-48295-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Effect of ipragliflozin on endothelial dysfunction in patients with type 2 diabetes and chronic kidney disease: a randomized clinical trial (PROCEED).2023

    • Author(s)
      Tanaka A, Okada Y, Torimoto K, Kamei N, Hirai H, Kono H, Sugimoto K, Teragawa H, Taguchi I, Maruhashi T, Sonoda S, Kurozumi A, Inagaki S, Oshita C, Hisauchi I, Takahashi K, Higashi Y, Shimabukuro M, Node K, on behalf of the PROCEED trial investigators.
    • Journal Title

      Diabetes Metab

      Volume: 49 Issue: 4 Pages: 101447-101447

    • DOI

      10.1016/j.diabet.2023.101447

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Lack of impact of ipragliflozin on endothelial function in patients with type 2 diabetes: sub-analysis of the PROTECT Study2023

    • Author(s)
      Kishimoto S, Higashi Y, Imai T, Eguchi K, Fukumoto K, Tomiyama H, Maemura K, Tanaka A, Node K; on behalf of the PROTECT investigators.
    • Journal Title

      Cardiovasc Diab

      Volume: 22 Issue: 1 Pages: 119-119

    • DOI

      10.1186/s12933-023-01856-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Lifelong heterogeneous contribution of cardiovascular risk factors to slow and fast progression of arterial stiffness.2023

    • Author(s)
      Tomiyama H, Shiina K, Nakano H, Takahashi T, Fujii M, Matsumoto C, Higashi Y, Yamashina A, Chikamori T.
    • Journal Title

      Hypertension

      Volume: 80 Issue: 10 Pages: 2159-2159

    • DOI

      10.1161/hypertensionaha.123.21481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Endothelial function in dyslipidemia: roles of LDL-cholesterol, HDL-cholesterol and triglycerides2023

    • Author(s)
      Higashi Y
    • Journal Title

      Cells

      Volume: 12 Issue: 9 Pages: 1293-1293

    • DOI

      10.3390/cells12091293

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors2023

    • Author(s)
      Kishimoto Shinji、Oda Nozomu、Maruhashi Tatsuya、Tanigawa Shunsuke、Mizobuchi Aya、Yusoff Farina Mohamad、Fujita Asuka、Uchiki Toshio、Kajikawa Masato、Yoshimura Kenichi、Yamaji Takayuki、Harada Takahiro、Hashimoto Yu、Nakano Yukiko、Hirota Seiko、Yoshinaga Shinji、Goto Chikara、Nakashima Ayumu、Higashi Yukihito
    • Journal Title

      Frontiers in Cardiovascular Medicine

      Volume: 10 Pages: 1122794-1122794

    • DOI

      10.3389/fcvm.2023.1122794

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
  • [Journal Article] Significant Correlates of Nocturnal Hypertension in Patients With Hypertension Who Are Treated With Antihypertensive Drugs2023

    • Author(s)
      Maruhashi Tatsuya,Kinoshita Yoshihiko,Ozono Ryoji,Nakamaru Mitsuaki,Ninomiya Masanori,Oiwa Jiro,Kawagoe Takuji,Yoshida Osamu,Matsumoto Toshiyuki,Fukunaga Yasuo,Sumii Kotaro,Ueda Hironori,Shiode Nobuo,Takahari Kosuke,Hayashi Yasuhiko,Ono Yujiro,Nakano Yukiko,Takahashi Masakazu,Kihara Yasuki,Higashi Yukihito
    • Journal Title

      American Journal of Hypertension

      Volume: 36 Issue: 6 Pages: 287-296

    • DOI

      10.1093/ajh/hpad014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11995, KAKENHI-PROJECT-23K24329
  • [Journal Article] Is carotid arterial stiffness a therapeutic target of statin therapy?2023

    • Author(s)
      Maruhashi T, Higashi Y
    • Journal Title

      Hypertens Res

      Volume: 46 Issue: 3 Pages: 768-768

    • DOI

      10.1038/s41440-022-01152-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] KCNJ5 mutation is a predictor for recovery of endothelial function after adrenalectomy in patients with aldosterone-producing adenoma2023

    • Author(s)
      Kishimoto Shinji、Oki Kenji、Maruhashi Tatsuya、Kajikawa Masato、Mizobuchi Aya、Harada Takahiro、Yamaji Takayuki、Hashimoto Yu、Yoshimura Kenichi、Nakano Yukiko、Goto Chikara、Yusoff Farina Mohamad、Nakashima Ayumu、Higashi Yukihito
    • Journal Title

      Hypertension Research

      Volume: 46 Issue: 9 Pages: 2213-2227

    • DOI

      10.1038/s41440-023-01375-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15131, KAKENHI-PROJECT-23K24329
  • [Journal Article] Genetic Risk of Primary Aldosteronism and Its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies2023

    • Author(s)
      Naito Tatsuhiko、Inoue Kosuke、Sonehara Kyuto、Baba Ryuta、Kodama Takaya、Otagaki Yu、Okada Akira、Itcho Kiyotaka、Kobuke Kazuhiro、Kishimoto Shinji、Yamamoto Kenichi、Morisaki Takayuki、Higashi Yukihito、Hinata Nobuyuki、Arihiro Koji、Hattori Noboru、Okada Yukinori、Oki Kenji、BioBank Japan
    • Journal Title

      Circulation

      Volume: 147 Issue: 14 Pages: 1097-1109

    • DOI

      10.1161/circulationaha.122.062349

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K20929, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-21K08557, KAKENHI-PROJECT-23K24329
  • [Journal Article] Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy2023

    • Author(s)
      Hashimoto Y, Yamaji T, Kitagawa T, Nakano Y, Kajikawa M, Yoshimura K, Chayama K, Goto C, Tanigawa S, Mizobuchi A, Harada T, Yusoff FM, Kishimoto S, Maruhashi T, Fujita A, Uchiki T, Nakashima A, Higashi Y
    • Journal Title

      J Clin Med

      Volume: 12 Issue: 7 Pages: 2534-2534

    • DOI

      10.3390/jcm12072534

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] A Multicenter Prospective Interventional Trial of Therapeutic Angiogenesis Using Bone Marrow-Derived Mononuclear Cell Implantation for Patients With Critical Limb-Threatening Ischemia Caused by Thromboangiitis Obliterans2023

    • Author(s)
      Fujioka A, Yanishi K, Yukawa A, Imai K, Yokota I, Fujikawa K, Yamada A, Shoji K, Kawamata H, Higashi Y, Ishigami T, Sasaki K, Taira S, Kuwahara K, Teramukai S Matoba S
    • Journal Title

      Circ J

      Volume: 87 Issue: 9 Pages: 1229-1237

    • DOI

      10.1253/circj.CJ-23-0046

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2023-08-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Mesenchymal stem/stromal cells for therapeutic angiogenesis2023

    • Author(s)
      Yusoff FM, Higashi Y.
    • Journal Title

      Cells

      Volume: 12 Issue: 17 Pages: 2162-2162

    • DOI

      10.3390/cells12172162

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Cardiovascular risk in patients receiving antihypertensive drug treatment from the perspective of endothelial function2022

    • Author(s)
      Maruhashi T, Higashi Y
    • Journal Title

      Hypertens Res

      Volume: 45 Issue: 8 Pages: 1322-1333

    • DOI

      10.1038/s41440-022-00936-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Effect of Novel Stratified Lipid Risk by “LDL-Window” and Flow-Mediated Dilation on the Prognosis of Coronary Artery Disease Using the FMD-J Study A Data2022

    • Author(s)
      Abe Shichiro、Haruyama Yasuo、Kobashi Gen、Toyoda Shigeru、Inoue Teruo、Tomiyama Hirofumi、Ishizu Tomoko、Kohro Takahide、Higashi Yukihito、Takase Bonpei、Suzuki Toru、Ueda Shinichiro、Yamazaki Tsutomu、Furumoto Tomoo、Kario Kazuomi、Koba Shinji、Takemoto Yasuhiko、et al.
    • Journal Title

      Circ J

      Volume: 86 Issue: 9 Pages: 1444-1454

    • DOI

      10.1253/circj.CJ-21-1068

    • ISSN
      1346-9843, 1347-4820
    • URL

      https://pure.teikyo.jp/en/publications/43036f60-8b32-421e-94b1-1189606f89e7

    • Year and Date
      2022-08-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-23K24329, KAKENHI-PROJECT-23K24330
  • [Journal Article] Long-Term Effect of Febuxostat on Endothelial Function in Patients With Asymptomatic Hyperuricemia: A Sub-Analysis of the PRIZE Study2022

    • Author(s)
      Maruhashi T, Higashi Y, Yoshida H, Tanaka A, Eguchi K, Tomiyama H, Kario K, Kato T, Oda N, Tahara N, Oguri M, Watada H, Node K
    • Journal Title

      Front Cardiovasc Med

      Volume: 9 Pages: 882821-882821

    • DOI

      10.3389/fcvm.2022.882821

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Relationship of Daily Coffee Intake with Vascular Function in Patients with Hypertension2022

    • Author(s)
      Yamaji Takayuki、Harada Takahiro、Hashimoto Yu、Nakano Yukiko、Kajikawa Masato、Yoshimura Kenichi、Goto Chikara、Mizobuchi Aya、Tanigawa Shunsuke、Yusoff Farina Mohamad、Kishimoto Shinji、Maruhashi Tatsuya、Nakashima Ayumu、Higashi Yukihito
    • Journal Title

      Nutrients

      Volume: 14 Issue: 13 Pages: 2719-2719

    • DOI

      10.3390/nu14132719

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
  • [Journal Article] Temporal Changes in Sparing and Enhancing Dose Protraction Effects of Ionizing Irradiation for Aortic Damage in Wild-Type Mice2022

    • Author(s)
      Hamada N, Kawano KI, Nomura T, Furukawa K, Yusoff FM, Maruhashi T, Maeda M, Nakashima A, Higashi Y
    • Journal Title

      Cancers

      Volume: 14 Issue: 14 Pages: 3319-3319

    • DOI

      10.3390/cancers14143319

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Isolated diastolic hypertension is not associated with endothelial dysfunction2022

    • Author(s)
      Han Y, Maruhashi T, Kajikawa M, Kishimoto S, Yamaji T, Harada T, Hashimoto Y, Yusoff FM, Nakano Y, Chayama K, Nakashima A, Goto C, Yoshimura K, Higashi Y.
    • Journal Title

      Hypertens ResInt

      Volume: 45(4) Issue: 4 Pages: 698-707

    • DOI

      10.1038/s41440-022-00854-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-23K24329
  • [Journal Article] White blood cell count is not associated with flow-mediated vasodilation or nitroglycerine-induced vasodilation2022

    • Author(s)
      Kishimoto Shinji、Maruhashi Tatsuya、Kajikawa Masato、Harada Takahiro、Yamaji Takayuki、Han Yiming、Mizobuchi Aya、Hashimoto Yu、Yoshimura Kenichi、Nakano Yukiko、Chayama Kazuaki、Goto Chikara、Yusoff Farina Mohamad、Nakashima Ayumu、Higashi Yukihito
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 8201-8201

    • DOI

      10.1038/s41598-022-12205-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
  • [Journal Article] Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease2022

    • Author(s)
      Higashi Y
    • Journal Title

      Antioxidants (Basel)

      Volume: 11 Issue: 10 Pages: 1958-1958

    • DOI

      10.3390/antiox11101958

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Self-reported total sitting time on a non-working day is associated with blunted flow-mediated vasodilation and blunted nitroglycerine-induced vasodilation2022

    • Author(s)
      Yamaji T, Harada T, Hashimoto Y, Nakano Y, Kajikawa M, Yoshimura K, Chayama K, Goto C, Han Y, Mizobuchi A, Yusoff FM, Kishimoto S, Maruhashi T, Nakashima A, Higashi Y.
    • Journal Title

      Sci Rep

      Volume: 12(1) Issue: 1 Pages: 6366-6366

    • DOI

      10.1038/s41598-022-10242-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
  • [Journal Article] Beneficial Effects of Supplementation on Endothelial Function: What Mechanisms?2022

    • Author(s)
      Higashi Y
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 29 Issue: 9 Pages: 1268-1270

    • DOI

      10.5551/jat.ED189

    • NAID

      130008134292

    • ISSN
      1340-3478, 1880-3873
    • Year and Date
      2022-09-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Serum Potassium Levels of 4.5 to Less Than 5.0 mmol/L Are Associated with Better Vascular Function2022

    • Author(s)
      Maruhashi T, Kajikawa M, Kishimoto S, Takaeko Y, Yamaji T, Harada T, Hashimoto Y, Han Y, Aibara Y, Yusoff FM, Nakano Y, Chayama K, Nakashima A, Goto C, Yoshimura K, Higashi Y.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 29 Issue: 11 Pages: 1588-1602

    • DOI

      10.5551/jat.63285

    • NAID

      130008132408

    • ISSN
      1340-3478, 1880-3873
    • Year and Date
      2022-11-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-23K24329
  • [Journal Article] The prevalence of cardiovascular disease is higher in patients with bilateral low ankle-brachial index than in patients with unilateral low ankle-brachial index2022

    • Author(s)
      Maruhashi Tatsuya、Kajikawa Masato、Kishimoto Shinji、Yamaji Takayuki、Harada Takahiro、Hashimoto Yu、Mizobuchi Aya、Tanigawa Shunsuke、Yusoff Farina Mohamad、Nakano Yukiko、Chayama Kazuaki、Nakashima Ayumu、Goto Chikara、Yoshimura Kenichi、Higashi Yukihito
    • Journal Title

      Atherosclerosis

      Volume: 360 Pages: 8-14

    • DOI

      10.1016/j.atherosclerosis.2022.09.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
  • [Journal Article] Implantation of Hypoxia-Induced Mesenchymal Stem Cell Advances Therapeutic Angiogenesis2022

    • Author(s)
      Yusoff FM, Nakashima A, Kawano KI, Kajikawa M, Kishimoto S, Maruhashi T, Ishiuchi N, Abdul Wahid SFS, Higashi Y.
    • Journal Title

      Stem Cells Int

      Volume: - Pages: 6795274-6795274

    • DOI

      10.1155/2022/6795274

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
  • [Journal Article] Early-Phase Changes in Serum Free Fatty Acid Levels After Glucose Intake Are Associated With Type 2 Diabetes Incidence: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases2022

    • Author(s)
      Sasaki N, Maeda R, Ozono R, Yoshimura K, Nakano Y, Higashi Y
    • Journal Title

      Diabetes Care

      Volume: 45 Issue: 10 Pages: 2309-2315

    • DOI

      10.2337/dc21-2554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Obesity and Endothelial Function2022

    • Author(s)
      Kajikawa M, Higashi Y
    • Journal Title

      Biomedicines

      Volume: 10 Issue: 7 Pages: 1745-1745

    • DOI

      10.3390/biomedicines10071745

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Relationship between hemoglobin A1c level and flow-mediated vasodilation in patients with type 2 diabetes mellitus receiving antidiabetic drugs2022

    • Author(s)
      Yamaji T, Harada T, Hashimoto Y, Nakano Y, Kajikawa M, Yoshimura K, Aoki G, Chayama K, Goto C, Mizobuchi A, Han Y, Yusoff FM, Kishimoto S, Maruhashi T, Nakashima A, Higashi Y.
    • Journal Title

      J Diabetes Investig

      Volume: 13(4) Issue: 4 Pages: 677-686

    • DOI

      10.1111/jdi.13705

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-23K24329
  • [Journal Article] Reply to a letter to the editor regarding "Short stature is associated with low flow-mediated vasodilation in Japanese men"2022

    • Author(s)
      Higashi Y, Kajikawa M, Harada T
    • Journal Title

      Hypertens Res

      Volume: 45 Issue: 7 Pages: 1221-1221

    • DOI

      10.1038/s41440-022-00919-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24329
  • [Journal Article] Perspectives on the management of hypertension in Japan2020

    • Author(s)
      Maruhashi Tatsuya、Kihara Yasuki、Higashi Yukihito
    • Journal Title

      Expert Opinion on Pharmacotherapy

      Volume: 21 Issue: 10 Pages: 1179-1187

    • DOI

      10.1080/14656566.2020.1724958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09758
  • [Journal Article] Association between Carotid Artery Calcification and Periodontal Disease Progression in Japanese Men and Women: A Cross-Sectional Study.2020

    • Author(s)
      Nanae Dewake, Yasuaki Ishioka, Keiichi Uchida, Akira Taguchi, Yukihito Higashi, Akihiro Yoshida, Nobuo Yoshinari
    • Journal Title

      J Clin Med

      Volume: 9 Issue: 10 Pages: 1-1

    • DOI

      10.3390/jcm9103365

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09611, KAKENHI-PROJECT-18K09758
  • [Journal Article] Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study2020

    • Author(s)
      Yamaji Takayuki、Harada Takahiro、Hashimoto Yu、Takaeko Yuji、Kajikawa Masato、Kihara Yasuki、Hida Eisuke、Chayama Kazuaki、Goto Chikara、Han Yiming、Yusoff Farina Mohamad、Kishimoto Shinji、Maruhashi Tatsuya、Nakashima Ayumu、Higashi Yukihito
    • Journal Title

      BMJ Open Diabetes Research & Care

      Volume: 8 Issue: 1 Pages: e001610-e001610

    • DOI

      10.1136/bmjdrc-2020-001610

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09758
  • [Journal Article] Association of Arterial Stiffness With Kidney Function Among Adults Without Chronic Kidney Disease2020

    • Author(s)
      Itano Seiji、Yano Yuichiro、Nagasu Hajime、Tomiyama Hirofumi、Kanegae Hiroshi、Makino Hirofumi、Higashi Yukihito、Kobayashi Yusuke、Sogawa Yuji、Satoh Minoru、Suzuki Kenji、Townsend Raymond R、Budoff Matthew、Bakris George、Kashihara Naoki
    • Journal Title

      American Journal of Hypertension

      Volume: 33 Issue: 11 Pages: 1003-1010

    • DOI

      10.1093/ajh/hpaa097

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02828, KAKENHI-PROJECT-18K09758
  • [Journal Article] Upstroke Time Is a Useful Vascular Marker for Detecting Patients With Coronary Artery Disease Among Subjects With Normal Ankle-Brachial Index2020

    • Author(s)
      Tatsuya Maruhashi, Yukihito Higashi, Yasuki Kihara, et al.
    • Journal Title

      J Am Heart Assoc .

      Volume: 9 Issue: 23

    • DOI

      10.1161/jaha.120.017139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08404
  • [Journal Article] Vascular function is further impaired in subjects aged 80 years or older2020

    • Author(s)
      Tatsuya Maruhashi, Yukihito Higashi, Yasuki Kihara, et al.
    • Journal Title

      Hypertens Res

      Volume: 43 Issue: 9 Pages: 914-921

    • DOI

      10.1038/s41440-020-0435-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08404, KAKENHI-PROJECT-18K09758
  • [Journal Article] Estimation of Arterial Viscosity Based on an Oscillometric Method and Its Application in Evaluating the Vascular Endothelial Function2019

    • Author(s)
      Tanaka Hiroshi、Mito Akihisa、Hirano Harutoyo、Soh Zu、Nakamura Ryuji、Saeki Noboru、Kawamoto Masashi、Higashi Yukihito、Yoshizumi Masao、Tsuji Toshio
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1

    • DOI

      10.1038/s41598-019-38776-4

    • NAID

      120006800828

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09758, KAKENHI-PROJECT-16K21076
  • [Journal Article] Effect of Empagliflozin on Endothelial Function in Patients With Type 2 Diabetes and Cardiovascular Disease: Results from the Multicenter, Randomized, Placebo-Controlled, Double-Blind EMBLEM Trial2019

    • Author(s)
      Tanaka Atsushi、Shimabukuro Michio、Machii Noritaka、Teragawa Hiroki、Okada Yosuke、Shima Kosuke R.、Takamura Toshinari、Taguchi Isao、Hisauchi Itaru、Toyoda Shigeru、Matsuzawa Yasushi、Tomiyama Hirofumi、Yamaoka-Tojo Minako、Yoshida Hisako、Sato Yasunori、Ikehara Yumi、Ueda Shinichiro、Higashi Yukihito、Node Koichi
    • Journal Title

      Diabetes Care

      Volume: 42 Issue: 10 Pages: e159-e161

    • DOI

      10.2337/dc19-1177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09758, KAKENHI-PROJECT-19K11371
  • [Journal Article] Does renal function have incremental predictive value of stroke in atrial fibrillation?2019

    • Author(s)
      Higashi Yukihito
    • Journal Title

      International Journal of Cardiology

      Volume: 274 Pages: 192-193

    • DOI

      10.1016/j.ijcard.2018.08.072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09758
  • [Journal Article] 呉市での骨粗鬆症に関する医科歯科連携-顎骨壊死・顎骨骨髄炎の予防と歯科用パノラマX線写真による骨粗鬆症スクリーニング-2019

    • Author(s)
      東森秀年,國原崇洋,田口 明,沖本信和
    • Journal Title

      日本骨粗鬆症学会誌

      Volume: 5 Pages: 9-14

    • NAID

      40021939465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09758
  • [Journal Article] Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus2019

    • Author(s)
      Kishimoto Shinji、Kinoshita Yoshihiko、Matsumoto Takeshi、Maruhashi Tatsuya、Kajikawa Masato、Matsui Shogo、Hashimoto Haruki、Takaeko Yuji、Kihara Yasuki、Chayama Kazuaki、Goto Chikara、Mohamad Yusoff Farina、Nakashima Ayumu、Noma Kensuke、Higashi Yukihito
    • Journal Title

      American Journal of Hypertension

      Volume: 32 Issue: 7 Pages: 695-702

    • DOI

      10.1093/ajh/hpz065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09758
  • [Journal Article] Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension2018

    • Author(s)
      Kajikawa M, Maruhashi T, Hidaka T, Nakano Y, Kurisu S, Matsumoto T, Iwamoto Y, Kishimoto S, Matsui S, Aibara Y, Yusoff FM, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Watanabe T, Tone H, Hibi M, Osaki N, Katsuragi Y, Higashi Y
    • Journal Title

      European Journal of Nutrition

      Volume: 印刷中 Issue: 3 Pages: 1611-1617

    • DOI

      10.1007/s00394-018-1611-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-17K09501
  • [Journal Article] Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery2018

    • Author(s)
      Kishimoto Shinji、Matsumoto Takeshi、Maruhashi Tatsuya、Iwamoto Yumiko、Kajikawa Masato、Oda Nozomu、Matsui Shogo、Hashimoto Haruki、Hidaka Takayuki、Kihara Yasuki、Chayama Kazuaki、Goto Chikara、Aibara Yoshiki、Yusoff Farina Binti Mohamad、Nakashima Ayumu、Noma Kensuke、Higashi Yukihito
    • Journal Title

      International Journal of Cardiology

      Volume: 260 Pages: 178-183

    • DOI

      10.1016/j.ijcard.2017.10.069

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Vascular Digit Injury in a College Baseball Player2018

    • Author(s)
      Maruhashi T, Kihara Y, Higashi Y.
    • Journal Title

      Circ J

      Volume: 82 Issue: 9 Pages: 2377

    • DOI

      10.1253/circj.CJ-17-1335

    • NAID

      130007438917

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2018-08-24
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Chronic kidney disease is associated with vascular smooth muscle dysfunction but not with endothelial dysfunction2018

    • Author(s)
      Iwamoto Yumiko、Maruhashi Tatsuya、Kajikawa Masato、Oda Nozomu、Kishimoto Shinji、Matsui Shogo、Hashimoto Haruki、Aibara Yoshiki、Yusoff Farina Mohamad、Hidaka Takayuki、Kihara Yasuki、Chayama Kazuaki、Noma Kensuke、Nakashima Ayumu、Goto Chikara、Higashi Yukihito
    • Journal Title

      International Journal of Cardiology

      Volume: 254 Pages: 284-290

    • DOI

      10.1016/j.ijcard.2017.10.122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Assessment of endothelium-independent vasodilation2018

    • Author(s)
      Maruhashi Tatsuya、Kihara Yasuki、Higashi Yukihito
    • Journal Title

      Journal of Hypertension

      Volume: 印刷中 Issue: 7 Pages: 1460-1467

    • DOI

      10.1097/hjh.0000000000001750

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Interrelationships Among Flow‐Mediated Vasodilation, Nitroglycerine‐Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors2018

    • Author(s)
      Tatsuya Maruhashi, Yumiko Iwamoto, Masato Kajikawa, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Haruki Hashimoto, Yoshiki Aibara, Farina Mohamad Yusoff, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, Ayumu Nakashima, Chikara Goto, Eisuke Hida, Yukihito Higashi
    • Journal Title

      Journal of the American Heart Association

      Volume: 7 Issue: 1 Pages: 1-9

    • DOI

      10.1161/jaha.117.006797

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K00049, KAKENHI-PROJECT-15K09084
  • [Journal Article] Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women2018

    • Author(s)
      Matsui Shogo、Kajikawa Masato、Maruhashi Tatsuya、Iwamoto Yumiko、Oda Nozomu、Kishimoto Shinji、Hashimoto Haruki、Hidaka Takayuki、Kihara Yasuki、Chayama Kazuaki、Hida Eisuke、Goto Chikara、Aibara Yoshiki、Nakashima Ayumu、Yusoff Farina Mohamad、Noma Kensuke、Kuwahara Yoshitaka、Matsubara Akio、Higashi Yukihito
    • Journal Title

      International Journal of Cardiology

      Volume: 261 Pages: 196-203

    • DOI

      10.1016/j.ijcard.2018.02.041

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-16K00049
  • [Journal Article] Endothelial function is impaired in relation to alcohol intake even in the case of light alcohol consumption in Asian men; Flow-mediated Dilation Japan (FMD-J) Study2017

    • Author(s)
      Oda N, Kajikawa M, Maruhashi T, Iwamoto Y, Kishimoto S, Matsui S, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Nakashima A, Noma K, Tomiyama H, Takase B, Yamashina A, Higashi Y
    • Journal Title

      Int J Cardiol

      Volume: 230 Pages: 523-528

    • DOI

      10.1016/j.ijcard.2016.12.065

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Decreased frequency and duration of tooth brushing is a risk factor for endothelial dysfunction2017

    • Author(s)
      Matsui Shogo、Kajikawa Masato、Maruhashi Tatsuya、Iwamoto Yumiko、Iwamoto Akimichi、Oda Nozomu、Kishimoto Shinji、Hidaka Takayuki、Kihara Yasuki、Chayama Kazuaki、Goto Chikara、Aibara Yoshiki、Nakashima Ayumu、Noma Kensuke、Taguchi Akira、Higashi Yukihito
    • Journal Title

      International Journal of Cardiology

      Volume: 241 Pages: 30-34

    • DOI

      10.1016/j.ijcard.2017.03.049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-15K11092
  • [Journal Article] Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women2017

    • Author(s)
      Kajikawa M, Oda N, Kishimoto S, Maruhashi T, Iwamoto Y, Iwamoto A, Matsui S, Aibara Y, Mohamad Yusoff FB, Hidaka T, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Taguchi A, Higashi Y
    • Journal Title

      Circ J

      Volume: 81 Issue: 6 Pages: 862-869

    • DOI

      10.1253/circj.CJ-16-1236

    • NAID

      130005679608

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-15K11092
  • [Journal Article] Is Serum Uric Acid a Biomarker, but not a Mediator in Patients With Lifestyle and Cardiovascular Diseases?2017

    • Author(s)
      Noma K, Kihara Y, Higashi Y.
    • Journal Title

      Int. Heart J.

      Volume: 58 Issue: 4 Pages: 467-469

    • DOI

      10.1536/ihj.17-301

    • NAID

      130005901261

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction2017

    • Author(s)
      (kajikawa M)Oda N, Maruhashi T, Kishimoto S, Kajikawa M, Iwamoto Y, Iwamoto A, Matsui S, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Nakashima A, Noma K, Hirano H, Higashi Y
    • Journal Title

      Am J Cardiol

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction2017

    • Author(s)
      Oda Nozomu、Maruhashi Tatsuya、Kishimoto Shinji、Kajikawa Masato、Iwamoto Yumiko、Iwamoto Akimichi、Matsui Shogo、Hidaka Takayuki、Kihara Yasuki、Chayama Kazuaki、Goto Chikara、Aibara Yoshiki、Nakashima Ayumu、Noma Kensuke、Hirano Harutoyo、Higashi Yukihito
    • Journal Title

      The American Journal of Cardiology

      Volume: 119 Issue: 12 Pages: 1983-1988

    • DOI

      10.1016/j.amjcard.2017.03.029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Decreased Frequency and Duration of Tooth Brushing Is a Risk Factor for Endothelial Dysfunction2017

    • Author(s)
      Matsui S, Kajikawa M, Maruhashi T, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Nakashima A, Noma K, Taguchi A, Higashi Y
    • Journal Title

      Int J Cardiol

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Endothelial dysfunction and abnormal vascular structure are simultaneously present in patients with heart failure with preserved ejection fraction2017

    • Author(s)
      Kishimoto S, Kajikawa M, Maruhashi T, Iwamoto Y, Matsumoto T, Iwamoto A, Oda N, Matsui S, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Nakashima A, Noma K, Higashi Y
    • Journal Title

      Int J Cardiol

      Volume: 231 Pages: 181-187

    • DOI

      10.1016/j.ijcard.2017.01.024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Mitral systolic velocity at peak exercise predicts impaired exercise capacity in patients with heart failure with preserved ejection fraction2017

    • Author(s)
      Masada K, Hidaka T, Harada Y, Kinoshita M, Itakura K, Higashi A, Utsunomiya H, Kihara Y
    • Journal Title

      Echocardiography

      Volume: 34 Issue: 2 Pages: 217-225

    • DOI

      10.1111/echo.13440

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Evaluation of end-tidal CO2 pressure at the anaerobic threshold for detecting and assessing pulmonary hypertension2017

    • Author(s)
      Higashi Akifumi、Dohi Yoshihiro、Yamabe Sayuri、Kinoshita Hiroki、Sada Yoshiharu、Kitagawa Toshiro、Hidaka Takayuki、Kurisu Satoshi、Yamamoto Hideya、Yasunobu Yuji、Kihara Yasuki
    • Journal Title

      Heart and Vessels

      Volume: 32 Issue: 11 Pages: 1350-1357

    • DOI

      10.1007/s00380-017-0999-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09503, KAKENHI-PROJECT-15K09084
  • [Journal Article] Optimal Target Level of Low-density Lipoprotein Cholesterol for Vascular Function in Statin Naive Individuals2017

    • Author(s)
      Matsui Shogo、Kajikawa Masato、Hida Eisuke、Maruhashi Tatsuya、Iwamoto Yumiko、Iwamoto Akimichi、Oda Nozomu、Kishimoto Shinji、Hidaka Takayuki、Kihara Yasuki、Chayama Kazuaki、Goto Chikara、Aibara Yoshiki、Nakashima Ayumu、Yusoff Farina Binti Mohamad、Noma Kensuke、Higashi Yukihito
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41598-017-09043-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K00049, KAKENHI-PROJECT-15K09084
  • [Journal Article] Outstanding Effect of Physical Exercise on Endothelial Function Even in Children and Adolescents2017

    • Author(s)
      Noma K, Kihara Y, Higashi Y.
    • Journal Title

      Circ J

      Volume: 81 Issue: 5 Pages: 637-639

    • DOI

      10.1253/circj.CJ-17-0291

    • NAID

      130005612032

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Long-term effect of sitagliptin on endothelial function in type 2 diabetes: a sub-analysis of the PROLOGUE study2016

    • Author(s)
      Maruhashi T, Higashi Y, Kihara Y, Yamada H, Sata M, Ueda S, Odawara M, Terauchi Y, Dai K, Ohno J, Iida M, Sano H, Tomiyama H, Inoue T, Tanaka A, Murohara T, Node K; PROLOGUE Study
    • Journal Title

      Cardiovasc Diabetol

      Volume: 15 Issue: 1 Pages: 134-134

    • DOI

      10.1186/s12933-016-0438-x

    • NAID

      120006937641

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Endothelial Function Assessed by Automatic Measurement of Enclosed Zone Flow-Mediated Vasodilation Using an Oscillometric Method Is an Independent Predictor of Cardiovascular Events2016

    • Author(s)
      Morimoto H, Kajikawa M, Oda N, Idei N, Hirano H, Hida E, Maruhashi T, Iwamoto Y, Kishimoto S, Matsui S, Aibara Y, Hidaka T, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Ukawa T, Tsuji T, Higashi Y
    • Journal Title

      J Am Heart Assoc

      Volume: - Issue: 12 Pages: 1-9

    • DOI

      10.1161/jaha.116.004385

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-16K21076
  • [Journal Article] Clinical value of regression of electrocardiographic left ventricular hypertrophy after aortic valve replacement2016

    • Author(s)
      Yamabe S, Dohi Y, Higashi A, Kinoshita H, Sada Y, Hidaka T, Kurisu S, Shiode N, Kihara Y; HERO (Hiroshima Heart Study Group) Investigators
    • Journal Title

      Heart Vessels

      Volume: 31 Issue: 9 Pages: 1497-1503

    • DOI

      10.1007/s00380-015-0761-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Corkscrew collaterals in Raynaud's syndrome2016

    • Author(s)
      Fujii Y, Teragawa H, Kihara Y, Higashi Y
    • Journal Title

      BMJ Case Rep

      Volume: - Pages: bcr2016215841-bcr2016215841

    • DOI

      10.1136/bcr-2016-215841

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Non-suppressive regulatory T cell subset expansion in pulmonary arterial hypertension2016

    • Author(s)
      Sada Y, Dohi Y, Uga S, Higashi A, Kinoshita H, Kihara Y
    • Journal Title

      Heart Vessels

      Volume: 31 Issue: 8 Pages: 1319-26

    • DOI

      10.1007/s00380-015-0727-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Relationship between serum triglyceride levels and endothelial function in a large community-based study2016

    • Author(s)
      Kajikawa M, Maruhashi T, Matsumoto T, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Matsui S, Aibara Y, Hidaka T, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Tomiyama H, Takase B, Yamashina A, Higashi Y
    • Journal Title

      Atherosclerosis

      Volume: 249 Pages: 70-75

    • DOI

      10.1016/j.atherosclerosis.2016.03.035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events.2016

    • Author(s)
      Kajikawa M, Maruhashi T, Hida E, Iwamoto Y, Matsumoto T, Iwamoto A, Oda N,Kishimoto S, Matsui S, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Nakashima A, Noma K, Higashi Y.
    • Journal Title

      Hypertension

      Volume: 67(5) Issue: 5 Pages: 1045-52

    • DOI

      10.1161/hypertensionaha.115.06839

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
  • [Journal Article] Circulating Level of Pigment Epithelium-derived Factor Is Associated with Vascular Function and Structure: a Cross-sectional Study.2016

    • Author(s)
      Masato Kajikawa, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi Iwamoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Yoshiki Aibara, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Kensuke Noma, Ayumu Nakashima, Takanori Matsui, Sho-ichi Yamagishi, Yukihito Higashi.
    • Journal Title

      International Journal of Cardiology

      Volume: 225 Pages: 91-95

    • DOI

      10.1016/j.ijcard.2016.09.123

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H07000, KAKENHI-PROJECT-15K09084
  • [Journal Article] Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease2016

    • Author(s)
      Iwamoto A, Kajikawa M, Maruhashi T, Iwamoto Y, Oda N, Kishimoto S, Matsui S, Kihara Y, Chayama K, Goto C, Noma K, Aibara Y, Nakashima A, Higashi Y
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 23 Issue: 11 Pages: 1261-1269

    • DOI

      10.5551/jat.35436

    • NAID

      130005268304

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Associations of number of teeth present with dental panoramic radiography measure in Japanese men and women 40 years and older: a cross-sectional study2016

    • Author(s)
      Takahashi M, Uchida K, Yamada S, Sugino N, Higashi Y, Yamada K, Taguchi A
    • Journal Title

      Osteoporosis and Sarcopenia

      Volume: 2 Issue: 4 Pages: 250-255

    • DOI

      10.1016/j.afos.2016.10.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11092
  • [Journal Article] Response to "circulating level of pigment epithelium-derived factor is associated with vascular function and structure: Methodological issues"2016

    • Author(s)
      Kajikawa M, Hida E, Kihara Y, Yamagishi SI, Higashi Y
    • Journal Title

      Int J Cardiol

      Volume: - Pages: 121-121

    • DOI

      10.1016/j.ijcard.2016.10.100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-16H07000
  • [Journal Article] Prognostic Factors for Survival in Pulmonary Hypertension Due to Left Heart Disease2016

    • Author(s)
      Yamabe S, Dohi Y, Fujisaki S, Higashi A, Kinoshita H, Sada Y, Hidaka T, Kurisu S, Yamamoto H, Kihara Y.
    • Journal Title

      Circ J

      Volume: 80 Issue: 1 Pages: 243-249

    • DOI

      10.1253/circj.CJ-15-0708

    • NAID

      130005116997

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease2016

    • Author(s)
      Maruhashi T, Kajikawa M, Nakashima A, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Matsui S, Higaki T, Shimonaga T, Watanabe N, Ikenaga H, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Noma K, Higashi Y
    • Journal Title

      Int J Cardiol

      Volume: 219 Pages: 312-316

    • DOI

      10.1016/j.ijcard.2016.06.050

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Osteoporosis, osteoporotic fractures, and carotid artery calcification detected on panoramic radiographs in Japanese men and women2016

    • Author(s)
      Iwamoto Y, Uchida K, Sugino N, Kuroiwa H, Kitamura Y, Udagawa N, Shinohara A, Higashi Y, Taguchi A
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol

      Volume: 121 Issue: 6 Pages: 673-680

    • DOI

      10.1016/j.oooo.2016.02.006

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K11092
  • [Journal Article] Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.2015

    • Author(s)
      Kajikawa M, Noma K, Nakashima A, Maruhashi T, Iwamoto Y, Matsumoto T, Iwamoto A, Oda N, Hidaka T, Kihara Y, Aibara Y, Chayama K, Sasaki S, Kato M, Dote K, Goto C, Liao JK, Higashi Y.
    • Journal Title

      Hypertension.

      Volume: 66(4) Issue: 4 Pages: 892-9

    • DOI

      10.1161/hypertensionaha.115.05587

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
  • [Journal Article] Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.2015

    • Author(s)
      Matsumoto T, Oki K, Kajikawa M, Nakashima A, Maruhashi T, Iwamoto Y, Iwamoto A, Oda N, Hidaka T, Kihara Y, Kohno N, Chayama K, Goto C, Aibara Y, Noma K, Liao JK, Higashi Y.
    • Journal Title

      Hypertension.

      Volume: 65(4) Issue: 4 Pages: 841-8

    • DOI

      10.1161/hypertensionaha.114.05001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
  • [Journal Article] Non-suppressive regulatory T cell subset expansion in pulmonary arterial hypertension.2015

    • Author(s)
      Sada Y, Dohi Y, Uga S, Higashi A, Kinoshita H, Kihara Y.
    • Journal Title

      Heart Vessels.

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] The Potential Role of Inflammation Associated with Interaction between Osteopontin and CD44 in a Case of Pulmonary Tumor Thrombotic Microangiopathy Caused by Breast Cancer2015

    • Author(s)
      Higashi A, Dohi Y, Uraoka N, Sentani K, Uga S, Kinoshita H, Sada Y, Kitagawa T, Hidaka T, Kurisu S, Yamamoto H, Yasui W, Kihara Y.
    • Journal Title

      Intern. Med.

      Volume: 54 Issue: 22 Pages: 2877-2880

    • DOI

      10.2169/internalmedicine.54.4749

    • NAID

      130005108845

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25460416
  • [Journal Article] History, Methodological Aspects, and Clinical Perspectives2015

    • Author(s)
      Higashi Y.
    • Journal Title

      Int. Heart J.

      Volume: 56 Issue: 2 Pages: 125-134

    • DOI

      10.1536/ihj.14-385

    • NAID

      130004941304

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Reduction in blood pressure improves impaired nitroglycerine-induced vasodilation in patients with essential hypertension.2015

    • Author(s)
      Maruhashi T, Nakashima A, Kishimoto S, Iwamoto A, Kajikawa M, Oda N, Kihara Y, Aibara Y, Noma K, Higashi Y.
    • Journal Title

      Hypertens Res.

      Volume: 38(12) Issue: 12 Pages: 862-8

    • DOI

      10.1038/hr.2015.93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Ratio of serum levels of AGEs to soluble form of RAGE is a predictor of endothelial function.2015

    • Author(s)
      Kajikawa M, Nakashima A, Fujimura N, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Oda N, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Noma K, Takeuchi M, Matsui T, Yamagishi S, Higashi Y.
    • Journal Title

      Diabetes Care.

      Volume: 38(1) Issue: 1 Pages: 119-25

    • DOI

      10.2337/dc14-1435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25670762
  • [Journal Article] Clinical value of regression of electrocardiographic left ventricular hypertrophy after aortic valve replacement.2015

    • Author(s)
      Yamabe S, Dohi Y, Higashi A, Kinoshita H, Sada Y, Hidaka T, Kurisu S, Shiode N, Kihara Y; HERO (Hiroshima Heart Study Group) Investigators.
    • Journal Title

      Heart Vessels.

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Journal Article] Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia2015

    • Author(s)
      Sugihara S, Hisatome I, Kuwabara M, Niwa K, Maharani N, Kato M, Ogino K, Hamada T, Ninomiya H, Higashi Y, Ichida K, Yamamoto K
    • Journal Title

      Circ J

      Volume: 79 Issue: 5 Pages: 1125-1132

    • DOI

      10.1253/circj.CJ-14-1267

    • NAID

      130005066259

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-25461058, KAKENHI-PROJECT-25670762
  • [Journal Article] Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial.2015

    • Author(s)
      Maruhashi T, Noma K, Fujimura N, Kajikawa M, Matsumoto T, Hidaka T, Nakashima A, Kihara Y, Liao JK, Higashi Y.
    • Journal Title

      Hypertens Res.

      Volume: 38(7) Issue: 7 Pages: 485-90

    • DOI

      10.1038/hr.2015.24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
  • [Journal Article] Endothelial dysfunction is associated with the severity of cerebral small vessel disease.2015

    • Author(s)
      Nezu T, Hosomi N, Aoki S, Sugimoto T, Kubo S, Araki M, Matsushima H, Mukai T, Takahashi T, Maruyama H, Higashi Y, Matsumoto M.
    • Journal Title

      Hyperten Res.

      Volume: 38 Issue: 4 Pages: 291-297

    • DOI

      10.1038/hr.2015.4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670762, KAKENHI-PROJECT-26293211
  • [Journal Article] A Multicenter, Double-Blind, Parallel Randomized Clinical Trial2015

    • Author(s)
      Higashi Y, Azuma N, Takeishi Y, Minamino T, Kihara Y, Node K, Sata M, Fukumoto Y, Origasa H, Matsuo H, Naritomi H, Fujita M, Shimizu W.
    • Journal Title

      Int. Heart J.

      Volume: 56 Issue: 6 Pages: 632-638

    • DOI

      10.1536/ihj.15-191

    • NAID

      130005113045

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-15K09143, KAKENHI-PROJECT-15K15306, KAKENHI-PLANNED-26115008, KAKENHI-PROJECT-25670762, KAKENHI-PROJECT-25293184
  • [Journal Article] Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration.2015

    • Author(s)
      Nakamura Y, Miyaki S, Ishitobi H, Matsuyama S, Nakasa T, Kamei N, Akimoto T, Higashi Y, Ochi M.
    • Journal Title

      FEBS Lett

      Volume: 589 Issue: 11 Pages: 1257-65

    • DOI

      10.1016/j.febslet.2015.03.031

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25253089, KAKENHI-PROJECT-25670762
  • [Journal Article] Oxidative stress and endothelial dysfunction: clinical evidence and therapeutic implications.2014

    • Author(s)
      Higashi Y, Maruhashi T, Noma K, Kihara Y.
    • Journal Title

      Trends Cardiovasc Med.

      Volume: 24(4) Issue: 4 Pages: 165-9

    • DOI

      10.1016/j.tcm.2013.12.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-25670762
  • [Journal Article] Borderline ankle-brachial index value of 0.91 to 0.99 is associated with endothelial dysfunction.2014

    • Author(s)
      Kajikawa M, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Noma K, Higashi Y.
    • Journal Title

      Circ J.

      Volume: 78 Pages: 1740-1745

    • NAID

      130004926966

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Circulating endothelial progenitor cells and placental abruption in women with preeclampsia.2014

    • Author(s)
      Sakashita T, Higashi Y, Soga J, Fujiwara H, Kudo Y.
    • Journal Title

      Pregnancy Hypertens.

      Volume: 4 Pages: 203-208

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Do incretins improve endothelial function (review)?2014

    • Author(s)
      Oyama J, Higashi Y, Node K.
    • Journal Title

      Cardiovasc Diabetol.

      Volume: 13 Issue: 3 Pages: 21-21

    • DOI

      10.3810/pgm.2013.05.2659

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Poor oral health behavior, decreased frequency of tooth brushing, is associated with endothelial dysfunction.2014

    • Author(s)
      Kajikawa M, Nakashima A, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Goto C, Taguchi A, Noma K, Higashi Y
    • Journal Title

      Circ J

      Volume: 25 Pages: 950-954

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592849
  • [Journal Article] Autonomic nervous activation triggered during induction of reactive hyperemia exerts a greater influence on the measured reactive hyperemia index by peripheral arterial tonometry than on flow-mediated vasodilatation of the brachial artery in patients with hypertension.2014

    • Author(s)
      Tomiyama H, Yoshida M, Higashi Y, Takase B, Furumoto T, Kario K, Ohya Y, Yamashina A.
    • Journal Title

      Hypertens Res.

      Volume: 37 Issue: 10 Pages: 914-918

    • DOI

      10.1038/hr.2014.103

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] A single consumption of curry improved postprandial endothelial function in healthy male subjects: a randomized, controlled crossover trial.2014

    • Author(s)
      Nakayama H, Tsuge N, Sawada H, Masamura N, Yamada S, Satomi S, Higashi Y.
    • Journal Title

      Nutr J.

      Volume: 13 Issue: 1 Pages: 67-67

    • DOI

      10.1186/1475-2891-13-67

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells.2014

    • Author(s)
      Maruhashi T, Noma K, Fujimura N, Idei, N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Goto C, Kihara Y, Chayama K, Liao JK, Higashi Y.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 10 Pages: e109017-e109017

    • DOI

      10.1371/journal.pone.0109017

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Poor oral health behavior, decreased frequency of tooth brushing, is associated with endothelial dysfunction2014

    • Author(s)
      Kajikawa M, Nakashima A, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Goto C, Taguchi A, Noma K, Higashi Y
    • Journal Title

      Circulation Journal

      Volume: 78 Pages: 950-954

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592849
  • [Journal Article] Poor oral health behavior, decreased frequency of tooth brushing, is associated with endothelial dysfunction.2014

    • Author(s)
      Kajikawa M, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Noma K, Taguchi A, Higashi Y.
    • Journal Title

      Circ J.

      Volume: 78 Pages: 950-954

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral arterial disease.2014

    • Author(s)
      Maruhashi T, Nakashima A, Matsumoto T, Oda N, Iwamoto Y, Iwamoto A, Kajikawa M, Kihara Y, Chayama K, Goto C, Noma K, Higashi Y.
    • Journal Title

      Atherosclerosis.

      Volume: 235 Issue: 1 Pages: 65-70

    • DOI

      10.1016/j.atherosclerosis.2014.04.012

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Rho-associated kinase is a predictor of a predictor of cardiovascular outcomes.2013

    • Author(s)
      Kajikawa M, Noma K, Maruhashi T, Mikami S, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Liao JK, Higashi Y.
    • Journal Title

      Hypertension.

      Volume: 64 Issue: 4 Pages: 856-864

    • DOI

      10.1161/hypertensionaha.113.02296

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591043, KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-25670762
  • [Journal Article] Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer2013

    • Author(s)
      Shinagawa K
    • Journal Title

      Int J Cancer

      Volume: 132 Issue: 4 Pages: 813-823

    • DOI

      10.1002/ijc.27735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390088, KAKENHI-PROJECT-24700979, KAKENHI-PROJECT-25670762
  • [Journal Article] Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model2013

    • Author(s)
      Mikami S, Nakashima A, Nakagawa K, Maruhashi T, Iwamoto Y, Kajikawa M, Matsumoto T, Kihara Y, Chayama K, Noma K, Ochi M, Nishimura M, Tsuji K, Kato Y, Goto C, Higashi Y
    • Journal Title

      PLOS ONE

      Volume: 8(7) Issue: 7 Pages: e67739-e67739

    • DOI

      10.1371/journal.pone.0067739

    • NAID

      120006986197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-24659876, KAKENHI-PROJECT-25670369, KAKENHI-PROJECT-25670762
  • [Journal Article] Promotion of skeletal muscle repair in rat skeletal muscle injury model by local injection of human adipose tissue-derived regenerative cells2013

    • Author(s)
      Ryo Mori, Kazunori Yokota
    • Journal Title

      Journal of Tissue Engineering and Regenerative Medicine

      Volume: in press Issue: 10 Pages: 1150-1160

    • DOI

      10.1002/term.1659

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592188, KAKENHI-PROJECT-25670762
  • [Journal Article] Rho-associated kinase is a predictor of a predictor of cardiovascular outcomes2013

    • Author(s)
      Kajikawa M, Noma K, Maruhashi T, Mikami S, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Liao JK, Higashi Y.
    • Journal Title

      Hypertension

      Volume: 64 Pages: 856-864

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Association between oral health and the risk of lacunar infarction in Japanese adults.2013

    • Author(s)
      Taguchi A, Miki M, Muto A, Kubokawa K, Migita K, Higashi Y, Yoshinari N.
    • Journal Title

      Gerontology

      Volume: 59 Issue: 6 Pages: 499-506

    • DOI

      10.1159/000353707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-24592849, KAKENHI-PROJECT-25670762, KAKENHI-PROJECT-25862063
  • [Journal Article] Nitroglycerine-induced Vasodilation for Assessment of Vascular Function: A Comparison with Flow-mediated Vasodilation.2013

    • Author(s)
      Maruhashi T, Soga J, Idei N, Fujimura N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 33 Issue: 6 Pages: 1401-1408

    • DOI

      10.1161/atvbaha.112.300934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-beta1 signaling.2013

    • Author(s)
      Ueno, T., Nakashima, A., DOI:, S., Kawamoto, T., Honda, K., Yokoyama, Y., DOI:, T., Higashi, Y., Yorioka, N., Kato, Y., Kohno, N., and Masaki, T
    • Journal Title

      Kidney Int

      Volume: 84(2) Issue: 2 Pages: 297-307

    • DOI

      10.1038/ki.2013.81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592068, KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-24659876, KAKENHI-PROJECT-25670762
  • [Journal Article] Nitroglycerine-induced Vasodilation for Assessment of Vascular Function: A Comparison with Flow-mediated Vasodilation.2013

    • Author(s)
      Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Impact of aldosterone-producing adenoma on cardiac structures in echocardiography.2013

    • Author(s)
      Hidaka T, Shiwa T, Fujii Y, Nishioka K, Utsunomiya H, Ishibashi K, Mitsuba N, Dohi Y, Oda N, Noma K, Kurisu S, Nakano Y, Yamamoto H, Ishida T, Higashi Y, Kihara Y.
    • Journal Title

      J Echocardiogr.

      Volume: 24 Pages: 185-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] A Novel Noninvasive and Simple Method for Assessment of Endothelial Function:Enclosed Zone Flow-Mediated Vasodilation (ezFMD) Using an Oscillation Amplitude Measurement.2013

    • Author(s)
      Idei N, Ukawa T, Kajikawa M, Iwamoto Y, Fujimura N, Maruhashi T, Mikami S, Matsumoto T, Kihara Y, Chayama K, Noma K, Nakashima A, Takayanagi T, Morimoto H, Tsuji T, Higashi Y.
    • Journal Title

      Circ J

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] A novel noninvasive and simple method for assessment of endothelial function: Enclosed zone flow-mediated vasodilation (ezFMD) using an oscillation amplitude measurement2013

    • Author(s)
      Naomi Idei, Teiji Ukawa, Masato Kajikawa, Yumiko Iwamoto, Noritaka Fujimura, Tatsuya Maruhashi, Shinsuke Mikami, Takeshi Matsumoto, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, Ayumu Nakashima, Tsuneo Takayanagi, Haruka Morimoto, Toshio Tsuji, and Yukihito Higashi
    • Journal Title

      Atherosclerosis

      Volume: 229(2) Issue: 2 Pages: 324-330

    • DOI

      10.1016/j.atherosclerosis.2013.05.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360118, KAKENHI-PROJECT-25670762
  • [Journal Article] Age-dependent decrease in the chondrogenic potential of human bone marrow mesenchymal stem cells expanded with fibroblast growth factor-22013

    • Author(s)
      Kanawa M, Igarashi A, Ronald VS, Higashi Y, Kurihara H, Sugiyama M, Saskianti T, Pan H, Kato Y
    • Journal Title

      Cytotherapy

      Volume: 15(9) Issue: 9 Pages: 1062-72

    • DOI

      10.1016/j.jcyt.2013.03.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-24659876, KAKENHI-PROJECT-25670762
  • [Journal Article] Association of carotid artery calcification detected on dental panoramic radiographs with a history of osteoporosis diagnosis without prevalent fractures.2013

    • Author(s)
      Taguchi A, Iwamoto Y, Yamada S, Sugino N, Kuroiwa H, Uchida K, Higashi Y
    • Journal Title

      J Radiol Radiat Ther

      Volume: 1 Pages: 1020-1020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592849
  • [Journal Article] Flow-mediated vasodilation and anatomical variation of brachial artery (double brachial artery) in healthy subjects and atherosclerotic patients.2013

    • Author(s)
      Fujii Y, Teragawa H, Soga J, Fujimura N, Idei N, Hidaka T, Hata T, Mikami S, Maruhashi T, Iwamoto Y, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
    • Journal Title

      Circ J

      Volume: 77 Pages: 1073-1080

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Resistin-Like Molecule β Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development.2013

    • Author(s)
      Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T.
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology

      Volume: 33 Issue: 8 Pages: 1986-1993

    • DOI

      10.1161/atvbaha.113.301546

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23591099, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PUBLICLY-25111705, KAKENHI-PROJECT-25460416, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-25670762
  • [Journal Article] Chronic intake of onion extract containing quercetin improved postprandial endothelial dysfunction in healthy men.2013

    • Author(s)
      Nakayama H, Tsuge N, Sawada H, Higashi Y.
    • Journal Title

      J Am Coll Nutr.

      Volume: 32 Issue: 3 Pages: 160-164

    • DOI

      10.1080/07315724.2013.797858

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670762
  • [Journal Article] Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study.2013

    • Author(s)
      Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Tomiyama H, Takase B, Yamashina A, Higashi Y.
    • Journal Title

      Heart

      Volume: 99(24) Issue: 24 Pages: 1837-1842

    • DOI

      10.1136/heartjnl-2013-304739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591081, KAKENHI-PROJECT-25670762
  • [Journal Article] Flow-Mediated Vasodilation and Anatomical Variation of the Brachial Artery (Double Brachial Artery) in Healthy Subjects and Patients with Cardiovascular Diseases.2013

    • Author(s)
      Fujii Y, Teragawa H, Soga J, Idei N, Fujimura N, Maruhashi T, Mikami S, Iwamoto Y, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
    • Journal Title

      Circ J

      Volume: 77 Pages: 1073-1080

    • NAID

      10031139013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women.2013

    • Author(s)
      Maruhashi T, Nakashima A, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Goto C, Noma K, Tomiyama H, Takase B, Yamashina A, Higashi Y.
    • Journal Title

      BMJ Open

      Volume: 2013 Nov 8;3(11) Issue: 11 Pages: e003659-e003659

    • DOI

      10.1136/bmjopen-2013-003659

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591081, KAKENHI-PROJECT-25670762
  • [Journal Article] Xanthine oxidoreductase is involved inmacrophage foam cell formation and atherosclerosis development2012

    • Author(s)
      Kushiyama A, Zhang J, Sakoda H, KikuchiT, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata, H, Kikuchi M, KawazuS, Higashi Y, Kurihara, H, Asano T.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 32 Pages: 291-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Geranylgeranylacetone, Hsp90/ AMPK/ eNOS/ NO pathway, and endothelial function in humans2012

    • Author(s)
      Fujimura N, Jitsuiki D, Goto C, Soga J, Hidaka T, Umemura T, Nishioka K, OshimaT, Chayama K, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 32 Pages: 153-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Vascular dysfunction even after 20 years in children exposed to passive smoking : alarming results and need for awareness2012

    • Author(s)
      Suzuki T, Tomiyama H, Higashi Y
    • Journal Title

      Arterioscler Thromb Vase Biol

      Volume: 32 Pages: 841-842

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Rho-associated kinase (ROCK) activity, endothelial function and cardiovascular risk factors2012

    • Author(s)
      Soga J, Hata T, Hidaka T, Fujii Y, Idei N, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Kato H, Noma K, Liao JK, Higashi Y
    • Journal Title

      Arterioscler Thromb Vase Biol

      Volume: 31 Pages: 2353-2359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] A study design of multi-center study to evaluatethe clinical usefulness of semi-automatic measurement offlow-mediated vasodilatation of thebrachial artery in Japan(FMD-J study)2012

    • Author(s)
      Tomiyama H, Kohro T, Higashi Y, Takase B, Suzuki T, Ishizu T, Ueda S, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Watanabe K, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Maemura K, Ohya Y, Furukawa T, Ito H, Yamashina A.
    • Journal Title

      Int Heart J.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Mineralocorticoid Receptor Blocker Eplerenone Improves Endothelial Function and Inhibits Rho-associated Kinase Activity in Patients With Hypertension2012

    • Author(s)
      Fujimura N, Noma K, Hata T, Soga J, Hidaka T, Idei N, Fujii Y, Mikami S, Maruhashi T, Iwamoto Y, Kihara Y, Chayama K, Kato H, Liao JK, Higashi Y.
    • Journal Title

      Clin Pharmacol Ther

      Volume: 91 Issue: 2 Pages: 289-297

    • DOI

      10.1038/clpt.2011.227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Striking Crosstalk of ROCK Signaling with Endothelial Function2012

    • Author(s)
      Noma K, Kihara Y, Higashi Y.
    • Journal Title

      J Cardiol

      Volume: 60 Pages: 1-6

    • NAID

      10031187760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Endothelial dysfunction and hypertension in aging.2012

    • Author(s)
      Higashi Y, Kihara Y, Noma K
    • Journal Title

      Hypertens Res

      Volume: 35 Issue: 11 Pages: 1039-47

    • DOI

      10.1038/hr.2012.138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-24592849
  • [Journal Article] Hyperbilirubinemia, Augmentation of Endothelial Function and Decrease in Oxidative Stress in Gilbert Syndrome.2012

    • Author(s)
      Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Kihara Y, Chayama K, Noma K, Nakashima A, Tomiyama H, Takase B, Yamashina A, Higashi Y.
    • Journal Title

      Circulation

      Volume: 126 Issue: 5 Pages: 598-603

    • DOI

      10.1161/circulationaha.112.105775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043, KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-24591081
  • [Journal Article] Geranyl-geranylacetone, heat shock protein 90/AMP-activated protein kinase/endothelial nitric oxide synthase/nitric oxide pathway, and endothelial function in humans2012

    • Author(s)
      Higashi Y(11人中11番目)
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 32 Issue: 1 Pages: 153-60

    • DOI

      10.1161/atvbaha.111.237263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592404
  • [Journal Article] Strings of ROCK activity and endothelial function(review)2012

    • Author(s)
      Noma K, Kihara Y, Higashi Y.
    • Journal Title

      J Cardiol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Endothelial function and hypertension in aging(review)2012

    • Author(s)
      Higashi Y, Noma K.
    • Journal Title

      Hypertens Res

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] How to Use Ezetimibe as an Anti-Atherogenic Agent via Inhibition of Rho-Kinase2012

    • Author(s)
      Noma K, Higashi Y.
    • Journal Title

      Circ J

      Volume: 76 Pages: 1836-1837

    • NAID

      10030504234

    • URL

      https://www.jstage.jst.go.jp/browse/circj/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Geranylgeranylacetone, Hsp90/AMPK/eNOS/NO pathway, and endothelial function in humans2012

    • Author(s)
      Fujimura N, Titsulki D, Goto C, Soga J, Hidaka T, Umemura T, Nishioka K, Oshima T, Chayama K, Higashi Y
    • Journal Title

      Arterioscler Thromb Vase Biol

      Volume: 32 Pages: 153-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development2012

    • Author(s)
      Kushiyama A, Zhang J, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushlyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata, H, Kikuchi M, Kawazu S, Higashi Y, Kurihara, H, Asano T
    • Journal Title

      Arterioscler Thromb Vase Biol

      Volume: 32 Pages: 291-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Geranylgeranylacetone, Hsp90/AMPK/eNOS/NO Pathway, and Endothelial Function in Humans.2012

    • Author(s)
      Fujimura N, Jitsuiki D, Maruhashi T, Mikami S, Iwamoto Y, Kajikawa M, Chayama K, Kihara Y, Noma K, Goto C, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 32 Pages: 153-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Intima-Media Thickness of Brachial Artery, Vascular Function, and Cardiovascular Risk Factors.2012

    • Author(s)
      Iwamoto Y, Maruhash T, Fujii Y, Idei N, Fujimura N, Mikami S, Kajikawa M, Matsumoto T, Kihara Y, Chayama K, Noma K, Nakashima A, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 32 Issue: 9 Pages: 2295-2303

    • DOI

      10.1161/atvbaha.112.249680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043, KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-24592849
  • [Journal Article] Selective mineralocorticoid receptor blocker eplerenone improves endothellal function and Inhibits Rho-associated kinase activity in patients with essential hypertension2012

    • Author(s)
      Fujimura N, Hata T, Soga J, Hidaka T, Idei N, Fujii Y, Mikami S, Maruhashi T, Iwamoto Y, Kihara Y, Chayama K, Kato H, Noma K, Liao JK, Higashi Y
    • Journal Title

      Clin Pharmacol & Therapeut

      Volume: 91 Pages: 289-297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] The therapeutic potential of ex vivo expanded CD133+ cells derived from human peripheral blood for peripheral nerve injuries2012

    • Author(s)
      Ohtsubo S, Ishikawa M, Kamei N, Kijima Y, Suzuki O, Sunagawa T, Higashi Y, MasudaH, Asahara T, Ochi M.
    • Journal Title

      J Neurosurg

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Vascular dysfunction even after 20 years inchildren exposed to passive smoking : alarming results and need for awareness2012

    • Author(s)
      Suzuki T, Tomiyama H, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 32 Pages: 841-842

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Selective mineralocorticoid receptor blockere plerenone improves endothelialfunction and inhibits Rho-associatedkinase activity in patients with essential hypertension2012

    • Author(s)
      Fujimura N, Hata T, Soga J, Hidaka T, IdeiN, Fujii Y, Mikami S, Maruhashi T, Iwamoto Y, Kihara Y, Chayama K, Kato H, Noma K, Liao JK, Higashi Y.
    • Journal Title

      Clin Pharmacol & Therapeut

      Volume: 91 Pages: 289-297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Color Doppler Flows of Corkscrew Collaterals in Thromboangiitis Obliterans (Buerger's Disease) Using Color Duplex Ultrasonography.2011

    • Author(s)
      Fujii Y, Soga J, Hidaka T, Hata T, Idei N, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Noma K, Higashi Y.
    • Journal Title

      J Am Coll Cardiol

      Volume: 57 Pages: 2539-2539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Measurement of Rho-associated kinase (ROCK) activity in humans : a comparison of leukocyte p-MBS/t-MBS and forearm blood flow response to fasudil. Atherosclerosis.2011

    • Author(s)
      Hata T, Soga J, Hidaka T, Idei N, Fujii Y, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Noma K, Liao JK, Higashi Y.
    • Journal Title

      Atherosclerosis.

      Volume: 214 Pages: 117-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Is cell therapy promising orlost in translation in patients withacute myocardial infarction2011

    • Author(s)
      Higashi Y.
    • Journal Title

      Circ J.

      Volume: 75 Pages: 546-547

    • NAID

      10028101734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Vascular Function and Circulating Progenitor Cells in Thromboangitis Obliterans (Buerger’s Disease) and Atherosclerosis Obliterans.2011

    • Author(s)
      Idei N, Nishioka K, Soga J, Hidaka T, Hata T, Fujii Y, Fujimura N, Maruhashi T, Mikami S, Teragawa H, Kihara Y, Noma K, Chayama K, Higashi Y.
    • Journal Title

      Hypertension

      Volume: 57 Pages: 70-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Vascular functionand circulating progenitor cell inthromboangiitis obliterans(Buergerdisease) and atherosclerosis obliterans2011

    • Author(s)
      Idei N, Nishioka K, Soga J, Hidaka T, HataT, Fujii Y, Fujimura N, Maruhashi T, Mikami S, Teragawa H, Kihara Y, Noma K, Chayama K, Higashi Y.
    • Journal Title

      Hypertension

      Volume: 57 Pages: 70-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients with Critical Limb Ischemia: A Comparison of Atherosclerotic Peripheral Arterial Disease and Buerger's Disease.2011

    • Author(s)
      Idei N, Soga J, Hata T, Fujii Y, Mikami S, Maruhashi T, Nishioka K, Hidaka T, Kihara Y, Chowdfury M, Noma K, Taguchi A, Chayama K, Sueda T, Higashi Y.
    • Journal Title

      Circ Cardiovasc Interv

      Volume: 4 Pages: 15-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Relationship among hyperuricemia, metabolic syndrome, and endothelial dysfunction2011

    • Author(s)
      Tomiyama H, Higashi Y, Takase B, Node K, Sata M, Inoue T, Ishibashi Y, Ueda S, Yamashina A.
    • Journal Title

      Am J Hypertens

      Volume: 24 Pages: 770-774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease).2011

    • Author(s)
      Fujii Y, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Noma K, Higashi Y.
    • Journal Title

      J Vasc Surg

      Volume: 54 Pages: 1689-1697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Calcium channel blockerand rho-associated kinae activity inpatients with hypertension2011

    • Author(s)
      Hata T, Soga J, Hidaka T, Idei N, FujiiY, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Kato H, Noma K, LiaoJK, Higashi Y.
    • Journal Title

      J Hypertens

      Volume: 29 Pages: 373-379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia : a comparison of atherosclerotic peripheral arterial disease and Buerger disease.2011

    • Author(s)
      Idei N, Chowdhury M, Soga J, Hata T, Fujii Y, Fujimura N, Mikami S, Maruhashi T, Nishioka K, Hidaka T, Kihara Y, Noma K, Taguchi A, Chayama K, Sueda T, Higashi Y.
    • Journal Title

      Circulation : Cardiovascular Intervention

      Volume: 4 Pages: 15-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] ROCK Study Group. Rho-associated kinase activity, endothelial function, and cardiovascular risk factors2011

    • Author(s)
      Higashi Y(14人中14番目)
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31 Issue: 10 Pages: 2353-9

    • DOI

      10.1161/atvbaha.111.227892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592404, KAKENHI-PROJECT-23591043
  • [Journal Article] Response to Letter Regarding Article, Autologous bone-marrow mononuclear cellimplantation reduces long-term major amputation risk in patients withcritical limb ischemia : a comparison ofatherosclerotic peripheral arterialdisease and Buerger disease2011

    • Author(s)
      Idei N, Chowdhury M, Soga J, Hata T, FujiiY, Fujimura N, Mikami S, Maruhashi T, Nishioka K, Hidaka T, Kihara Y, Noma K, Taguchi A, Chayama K, Sueda T, Higashi Y.
    • Journal Title

      Circulation : Cardiovascular Intervention

      Volume: 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Response to Letter Regarding Article, Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia : a comparison of atherosclerotic peripheral arterial disease and Buerger disease.2011

    • Author(s)
      Idei N, Chowdhury M, Soga J, Hata T, Fujii Y, Fujimura N, Mikami S, Maruhashi T, Nishioka K, Hidaka T, Kihara Y, Noma K, Taguchi A, Chayama K, Sueda, T, Higashi Y.
    • Journal Title

      Circulation : Cardiovascular Intervention

      Volume: 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Vascular function and circulating progenitor cell in thromboangitis obliterans (Buerger's disease) and atherosclerosis obliterans.2011

    • Author(s)
      Idei N, Nishioka K, Soga J, Hidaka T, Hata T, Fujii Y, Fujimura N, Maruhashi T, Mikami S, Teragawa H, Kihara Y, Noma K, Chayama K, Higashi Y
    • Journal Title

      Hypertension

      Volume: 57 Pages: 70-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Rho-Associated Kinase (ROCK) Activity, Endothelial Function and Cardiovascular Risk Factors.2011

    • Author(s)
      Soga J, Noma K, Hata T, Hidaka T, Fujii Y, Idei N, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, MD, Kato H, Liao JK, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31 Pages: 2353-2359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Journal Article] Color Doppler flows of corkscrew collaterals in thromboangiitis obliterans(Buergerdisease) using color duplex ultrasonography2011

    • Author(s)
      Fujii Y, Soga J, Hidaka T, Hata T, IdeiN, Fujimura N, Mikami S, Maruhashi T, Noma K, Kihara Y, Higashi Y.
    • Journal Title

      J Am Coll Cardiol

      Volume: 57 Pages: 2539-2539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Flow-mediated vasodilation is augmented in corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Bureger disease)2011

    • Author(s)
      Fujii Y, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Noma K, Higashi Y
    • Journal Title

      J Vas Surg

      Volume: 54 Pages: 1689-1697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Color Doppler flows of corkscrew collaterals in thromboangiitis obliterans (Buerger disease) using color duplex ultrasonography2011

    • Author(s)
      Fujii Y, Soga J, Hidaka T, Hata T, Idei N, Fujimura N, Mikami S, Maruhashi T, Noma K, Kihara Y, Higashi Y
    • Journal Title

      J Am Coll Cardiol

      Volume: 57 Pages: 2539-2539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia : A comparison of atherosclerotic peripheral arterial disease and buerger disease2011

    • Author(s)
      Taguchi A(16人中13番目), Higashi Y(16人中16番目)
    • Journal Title

      Circ Cardiovasc Interv

      Volume: 4 Issue: 1 Pages: 15-25

    • DOI

      10.1161/circinterventions.110.955724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592404, KAKENHI-PROJECT-23593074
  • [Journal Article] Rho-associated kinase(ROCK) activity, endothelial functionand cardiovascular risk factors2011

    • Author(s)
      Soga J, Hata T, Hidaka T, Fujii Y, IdeiN, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Kato H, Noma K, LiaoJK, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31 Pages: 2353-2359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Autologous bone-marrow mononuclear cellimplantation reduces long-term majoramputation risk in patients withcritical limb ischemia : a comparison ofatherosclerotic peripheral arterialdisease and Buerger disease2011

    • Author(s)
      Idei N, Chowdhury M, Soga J, Hata T, FujiiY, Fujimura N, Mikami S, Maruhashi T, Nishioka K, Hidaka T, Kihara Y, Noma K, Taguchi A, Chayama K, Sueda T, Higashi Y.
    • Journal Title

      Circulation : Cardiovascular Intervention

      Volume: 4 Pages: 15-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Flow-mediated vasodilation is augmented in corkscrew collateral arterycompared with that in a native artery inpatients with thromboangiitis obliterans(Bureger disease)2011

    • Author(s)
      Fujii Y, Fujimura N, Mikami S, MaruhashiT, Kihara Y, Chayama K, Noma K, Higashi Y.
    • Journal Title

      J Vas Surg

      Volume: 54 Pages: 546-547

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Is cell therapy promising or lost in translation in acute myocardial infarction?2011

    • Author(s)
      Higashi Y
    • Journal Title

      Circulation Journal

      Volume: 75 Pages: 546-547

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Calcium channel blocker and rho-associated kinase activity in patients with hypertension.2011

    • Author(s)
      Hata T, Soga J, Hidaka T, Idei N, Fujii Y, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Kato H, Noma K, Liao JK, Higashi Y
    • Journal Title

      Journal of Hypertension

      Volume: 29 Pages: 373-379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Measurement of Rho-associatedkinase(ROCK) activity in humans : acomparison of leukocyte p-MBS/ t-MBS and forearm blood flow response to fasudil2011

    • Author(s)
      Hata T, Soga J, Hidaka T, Idei N, FujiiY, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Noma K, Liao JK, Higashi Y.
    • Journal Title

      Atherosclerosis

      Volume: 241 Pages: 117-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Classification of corkscrew collateralsin thromboangiitis obliterans(Buerger' s disease): relationship between corkscrew type and prevalence of ischemic ulcers2010

    • Author(s)
      Fujii Y, Nishioka K, Nakamura S, HidakaT, Soga J, Hata T, Idei N, Fujimura N, Chayama K, Kihara Y, Higashi Y.
    • Journal Title

      Circ J.

      Volume: 74 Pages: 1684-1688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Increased leukocyte Rhokinase(ROCK) and endothelial dysfunction in cigarette smokers2010

    • Author(s)
      Hidaka T, Hata T, Soga J, Nakamura S, Fujii Y, Idei N, Fujimura N, Nishioka K, Kihara Y, Chayama K, Noma K, Liao JK, Higashi Y.
    • Journal Title

      Hypertens Res

      Volume: 33 Pages: 354-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Mesenchymal stem cellsenhance growth and metastasis of coloncancer2010

    • Author(s)
      Shinagawa K, Kitadai Y, Tanaka M, SumidaT, Kodama M, Higashi Y, Tanaka S, YasuiW, Chayama K.
    • Journal Title

      Int J Cancer

      Volume: 127 Pages: 2323-2333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Sarpogrelate, a selective 5-HT_<2A> antagonist, augments autologous bone-marrow mononuclear cell implantation-induced improvement in endothelium-dependent vasodilation in patients with critical limb ischemia2010

    • Author(s)
      Higashi Y, Miyazaki M, Goto C, Sanada H, Chayama K, Sueda T.
    • Journal Title

      J Cardiovasc Pharmacol 55

      Pages: 56-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] on the behalf of the SEASON investigators. Study design of SEASON registry : prospective Surveillance of vascular Events in antiplatelet-treated Artero Sclerosis Obliterans patients inJapaN(SEASON)2010

    • Author(s)
      Higashi Y, Fujita M, Origasa H, NaritomiH, Matsuo H, Miyata T, Shigematsu H.
    • Journal Title

      Int Heart J

      Volume: 51 Pages: 337-342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Study design of SEASON registry : prospective Surveillance of vascular Events in antiplatelet-treated ArteroSclerosis Obliterans patients in JapaN (SEASON).2010

    • Author(s)
      Higashi Y, Fujita M, Origasa H, Naritomi H, Matsuo H, Miyata T, Shigematsu H, on the behalf of the SEASON investigators.
    • Journal Title

      International Heart Journal

      Volume: 51 Pages: 337-342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Impaired coronary microvascular endothelial function in men with metabolic syndrome2010

    • Author(s)
      Teragawa H, Mitsuba N, Nishioka K, UedaK, Kono S, Higashi Y, Chayama K, Kihara Y.
    • Journal Title

      World J Cardiol

      Volume: 2 Pages: 205-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Endothelial function in subjects with isolated low HDL cholesterol : role of nitric oxide andcirculating progenitor cells2010

    • Author(s)
      Higashi Y, Matsuoka H, Umei H, Sugano R, Soga J, Fujii Y, Chayama K, Kihara Y, Imaizumi T.
    • Journal Title

      Am J Physiol Endorinol Metab

      Volume: 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Endothelial function in subjects with isolated low HDL cholesterol : role of nitric oxide and circulating progenitor cells2010

    • Author(s)
      Higashi Y, Matsuoka H, Umei H, Sugano R, Soga J, Fujii Y, Chayama K, Kihara Y, Imaizumi T.
    • Journal Title

      Am J Physiol Endormol Metab 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Sarpogrelate, aselective 5-HT_<2A> antagonist, augments autologous bone-marrow mononuclear cellimplantation-induced improvement in endothelium-dependent vasodilation in patients with critical limb ischemia2010

    • Author(s)
      Higashi Y, Miyazaki M, Goto C, Sanada H, Chayama K, Sueda T.
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: 55 Pages: 56-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Endothelial function in subjects with isolated low HDL cholesterol : role of nitric oxide and circulating progenitor cells.2010

    • Author(s)
      Higashi Y, Matsuoka H, Umei H, Sugano R, Soga J, Fujii Y, Chayama K, Kihara Y, Imaizumi T.
    • Journal Title

      Am J Physiol Endorinol Metab.

      Volume: 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Pioglitazone improves endothelium-dependent vasodilation in hypertensive patients with impairedglucose tolerance through a decrease inoxidative stress2010

    • Author(s)
      Hidaka T, Nakagawa K, Goto C, Soga J, Fujii Y, Hata T, Idei N, Fujimura N, Chayama K, Kihara Y, Higashi Y.
    • Journal Title

      Atherosclerosis

      Volume: 210 Pages: 521-524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Sarpogrelate, a selective 5-HT_<2A> antagonist, augments autologous bone-marrow mononuclear cell implantation-induced improvement in endothelium-dependent vasodilation in patients with critical limb ischemia.2010

    • Author(s)
      Higashi Y, Miyazaki M, Goto C, Sanada H, Chayama K, Sueda T.
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: 55 Pages: 56-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Endothelial function in subjects with isolated low HDL cholesterol : role of nitric oxide and circulating progenitor cells2010

    • Author(s)
      Higashi Y, Matsuoka H, Umei H, Sugano R, Fujii Y, Soga J, Kihara Y, Chayama K, Imaizumi T
    • Journal Title

      Am J Physiol Endocrinol Metab

      Volume: 298 Issue: 2 Pages: E202-E209

    • DOI

      10.1152/ajpendo.00394.2009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592404
  • [Journal Article] Anti-Aging Medicine in Cardiovascular Disease(review)2010

    • Author(s)
      Morishita R, Komuro I, Horiuchi M, Nakagami H, Minamino T, Higashi Y.
    • Journal Title

      Anti-Aging Medicine

      Volume: 7 Pages: 45-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease2009

    • Author(s)
      Higashi Y, Goto C, Hidaka T, Soga J, Nakamura S, Fujii Y, Hata T, Idei N, Fujimura N, Chayama K, Kihara Y, Taguchi A
    • Journal Title

      Atherosclerosis 206

      Pages: 604-610

    • NAID

      120001898374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease2009

    • Author(s)
      Higashi Y, Goto C, Hidaka T, Soga J, Nakamura S, Fujii Y, Hata T, Idei N, Fujimura N, Chayama K, Kihara Y, Taguchi A.
    • Journal Title

      Atherosclerosis

      Volume: 206 Pages: 604-610

    • NAID

      120001898374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Oxidative stress and endothelial function in cardiovascular diseases (review)2009

    • Author(s)
      Higashi Y, Noma K, Yoshizumi M, Kihara Y
    • Journal Title

      Circ J 73

      Pages: 411-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Dietary Phosphorus Acutely Impairs Endothelial Function2009

    • Author(s)
      Shuto E, Taketani Y, Tanaka R, Harada N, Isshiki M, Sato M, Nashiki K, Amo K, Yamamoto H, Higashi Y, Nakaya N, Takeda E
    • Journal Title

      J Am Soc Nephrol 20

      Pages: 1504-1512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Cigarette smoking abolished ischemic preconditioning-induced augmentation of endothelium-dependent vasodilation2009

    • Author(s)
      Nakamura S, Kimura M, Goto C, Kensuke N, Yoshizumi M, Chayama K, Kihara Y, Higashi Y
    • Journal Title

      Hypertension 53

      Pages: 674-681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Cigarette smoking abolished ischemic preconditioning-induced augmentation of endothelium-dependent vasodilation2009

    • Author(s)
      Nakamura S, Kimura M, Goto C, Kensuke N, Yoshizumi M, Chayama K, Kihara Y, Higashi Y.
    • Journal Title

      Hypertension

      Volume: 53 Pages: 674-681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Edaravone for Extending the therapeutic time window and rescue of ischemic penumbra in acute cerebralinfarction : role of endothelium-derivednitric oxide and oxidative stress(review)2009

    • Author(s)
      Higashi Y.
    • Journal Title

      Expert Opin Pharmaco

      Volume: 10 Pages: 323-331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Edaravone for Extending the therapeutic time window and rescue of ischemic penumbra in acute cerebral infarction : role of endothelium-derived nitric oxide and oxidative stress (review)2009

    • Author(s)
      Higashi Y
    • Journal Title

      Expert Opin Pharmaco 10

      Pages: 323-331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Dietary Phosphorus Acutely Impairs Endothelial Function2009

    • Author(s)
      Shuto E, Taketani Y, Tanaka R, Harada N, Isshiki M, Sato M, Nashiki K, Amo K, Yamamoto H, Higashi Y, Nakaya N, Takeda E.
    • Journal Title

      J Am Soc Nephrol

      Volume: 20 Pages: 1504-1512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Oxidative stress and endothelial function in cardiovascular diseases(review)2009

    • Author(s)
      Higashi Y, Noma K, Yoshizumi M, Kihara Y
    • Journal Title

      Circ J.

      Volume: 73 Pages: 411-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Journal Article] Periodontal infection is associated with endothelial dysfunction in humans.2008

    • Author(s)
      Higashi Y, Jitsuiki D, Goto C, Umemura T, Nishioka K, Hidaka T, Takemoto T, Nakamura S, Nakagawa K, Oshima T, Chayama K, Yoshizumi M, Taguchi A.
    • Journal Title

      Hypertension. 51

      Pages: 446-453

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Periodontal infection is associated with endothelial dysfunction in humans2008

    • Author(s)
      Higashi Y, Jitsuiki D, Goto C, Umemura T, Nishioka K, Hidaka T, Takemoto T, Nakamura S, Nakagawa K, Oshima T, Chayama K, Yoshizumi M, Taguchi A.
    • Journal Title

      Hypertension. 51

      Pages: 446-453

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Periodontal infection is associated with endothelial dysfunction in humans2008

    • Author(s)
      Higashi, Y
    • Journal Title

      Hypertension 51

      Pages: 446-453

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] The common and in vivo location-dependent markers for bone marrow mesenchymal stem cells isolated from jaw, iliac, femur, and tibia.2007

    • Author(s)
      Igarashi A, Segoshi K, Sakai Y, Pan H, Kanawa M, Higashi Y, Sugiyama M, Nakamura K, Kurihara H, Yamaguchi S, Tsuji K, Kawamoto T, Kato Y.
    • Journal Title

      Tissue Engineering. 13

      Pages: 2405-2417

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] The common and in vivo location-dependent markers for bone marrowmesenchymal stem cells isolated from jaw, iliac, femur, and tibia.2007

    • Author(s)
      Igarashi A, Segoshi K, Sakai Y, Pan H, Kanawa M, Higashi Y; Sugiyama M, Nakamura K, Kurihara H, Yamaguchi S, Tsuji K, Kawamotto T, Kato Y.
    • Journal Title

      Tissue Engineering. 13

      Pages: 2405-2417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Carvedilol improves endothelium-dependent vasodilation in patients withdilated cardiomyopathy.2007

    • Author(s)
      Nishioka K, Nakagawa K, Umemura T, Jitsuiki D, Ueda K, Goto C, Chayama K, Yoshizumi M, Higashi Y.
    • Journal Title

      Heart. 93

      Pages: 247-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] The effects of different intensities of acute exercise on systemic hemodynamics and forearm vascular function in humans.2007

    • Author(s)
      Goto C, Nishioka K, Umemura T, Jitsuiki D, Sakaguchi A, Kawamura M, Yoshizumi M, Chayama K, Higashi Y.
    • Journal Title

      Am J Hypertens. 20

      Pages: 825-830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] The effects of different intensities of acute exercise on systemic hemodynamics and forearm vascular function in humans.2007

    • Author(s)
      Goto C, Nishioka K, Umemura T, Jitsuiki D, Sakaguchi A, Kawamura M, Yoshizumi M, Chayama K, Higashi Y:
    • Journal Title

      Am J Hypertens. 20

      Pages: 825-830

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Roles of ROCK and oxidative stress in the pathogenesis of aortic stiffness.2007

    • Author(s)
      Noma K, Goto C, Nishioka K, Jitsuiki D, Umemura T, Ueda K, Kimura M, Nakagawa K, Oshima T, Chayama K, Yoshizumi M, Liao JK, Higashi Y.
    • Journal Title

      J Am Coll Cardiol. 49

      Pages: 698-705

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Corkscrew collaterals in thromboangitis obliterans(Buerger's disease).2007

    • Author(s)
      Fujii Y, Nishioka K, Yoshizumi M, Chayama K, Higashi Y.
    • Journal Title

      Circulation. 116

      Pages: 539-540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans: role of endothelium-derived nitric oxide and endothelial progenitor cells.2007

    • Author(s)
      Kimura M, Goto C, Umemura T, Ueda K, Nishioka K, Jitsuiki D, Yoshizumi M, Chayama K, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol 27

      Pages: 1403-1410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Sarpogrelate hydrochloride, a selective 5-HT_<2A> antagonist, improves vascular function in patients with peripheral arterial disease.2007

    • Author(s)
      Miyazaki M, Higashi Y, Goto C, Chayama K, Yoshizumi M, Sanada H, Sueda T.
    • Journal Title

      J Cardiovasc Pharm. 49

      Pages: 221-227

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Interaction of obesity and skeletal bone mineral density on tooth retention in Japanese postmenopausal women.2007

    • Author(s)
      Taguchi A, Tsuda M, Ohtsuka M, Nakamoto T, Inagaki K, Noguchi T, Kudo Y, Yoshizumi M, Higashi Y, Suei Y, Tanimoto K.
    • Journal Title

      Menopause. 14

      Pages: 500-504

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Measurement of flow-mediated vasodilation of the brachial artery: a comparison of measurements in the sitting and supine positions.2007

    • Author(s)
      Soga J, Nishioka K, Nakamura S, Umemura T, Jitsuiki D, Hidaka T, Teragawa H, Goto C, Chayama K, Yoshizumi M, Higashi Y.
    • Journal Title

      Circ J. 71

      Pages: 736-740

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans: role of endothelium-derived nitric oxide and endothelial progenitor cells.2007

    • Author(s)
      Kimura M, Goto C, Umemura T, Ueda K, Nishioka K, Jitsuiki D, Yoshizumi M, Chayama K, Higashi Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 27

      Pages: 1403-1410

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Carvedilol improves endothelium-dependent vasodilation in patients with dilated cardiomyopathy.2007

    • Author(s)
      Nishioka K, Nakagawa K, Umemura T, Jitsuiki D, Ueda K, Goto C, Chayama K, Yoshizumi M, Higashi Y.
    • Journal Title

      Heart. 93

      Pages: 247-248

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Corkscrew collaterals in thromboangitis obliterans (Buerger's disease).2007

    • Author(s)
      Fujii Y, Nishioka K, Yoshizumi M, Chayama K, Higashi Y.
    • Journal Title

      Circulation. 116

      Pages: 539-540

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans.2007

    • Author(s)
      Nishioka K, Hidaka T, Takemoto H, Nakamura S, Umemura T, Jitsuiki D, Soga J, Goto C, Chayama K, Yoshizumi M, Higashi Y.
    • Journal Title

      Hypertens Res. 30

      Pages: 775-780

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Oxidative stress, endothelial function, and angiogenesis induced by cell therapy and gene therapy (review)2006

    • Author(s)
      Higashi, Y
    • Journal Title

      Curr Pharm Biotechnol 7

      Pages: 109-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production and decrease in reactive oxygen species.2006

    • Author(s)
      Higashi Y, Sasaki S, Nakagawa K, Kumura M, Noma K, Hara K, Jitsuki D, Goto C, Oshima T, Chayama K, Yoshizumi M.
    • Journal Title

      Atherosclerosis. 186

      Pages: 390-395

    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for cardiovascular diseases (review).2006

    • Author(s)
      Higashi Y, Jitsiki D, Chayama K, Yoshizumi M.
    • Journal Title

      Recent Patent on Cardiovascular Drug Discovery. 1

      Pages: 85-93

    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Autologus bone-marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome.2006

    • Author(s)
      Umemura T, Nishioka K, Ochi M, Chayama K, Yoshizumi M, Higashi Y.
    • Journal Title

      Circ J. 70

      Pages: 1362-1364

    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production and decrease in reactive oxygen species2006

    • Author(s)
      Higashi, Y
    • Journal Title

      Atherosclerosis 186

      Pages: 390-395

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Effects of acute administration of caffeine on vascular function.2006

    • Author(s)
      Umemura T, Ueda K, Nishioka K, Hidaka T, Takemoto H, Nakamura S, Jitsuki D, Soga J, Goto C, Chayama K, Yoshizumi M, Higashi Y.
    • Journal Title

      Am J Cardiol. 98

      Pages: 1538-1541

    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Edaravone (3-methyl-l-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for cardiovascular diseases (review)2006

    • Author(s)
      Higashi, Y
    • Journal Title

      Recent Patent Reviews on Cardiovascular Drug 1

      Pages: 85-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Oxidative stress, endothelial function, and angiogenesis induced by cell therapy an dgene therapy(review).2006

    • Author(s)
      Higashi Y, Nishioka K, Umenura T, Chayama K, Yoshizumi M.
    • Journal Title

      Curr Pharm Biotechnol. 7

      Pages: 109-116

    • Data Source
      KAKENHI-PROJECT-18590815
  • [Journal Article] Association of helicobacter pylori infection with systemic inflammation and endothelial dysfunction in healthy male subjects.2005

    • Author(s)
      Oshima T, Higashi Y(他8名, 6番目)
    • Journal Title

      J Am Coll Cardiol (In press)

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Vascular function in patients with peripheral arterial disease : a comparison of upper and lower extremities.2005

    • Author(s)
      Sanada H, Higashi Y(他4名, 2番目)
    • Journal Title

      Atherosclerosis 178

      Pages: 179-185

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Angiotensin II type I receptor blocker and endothelial function in humans : role of nitric oxide and oxidative stress(review).2005

    • Author(s)
      Higashi Y(他2名)
    • Journal Title

      Current Medicinal Chemistry-Cardiovascular & Hematological Agents (In press)

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Angiotensin II type I receptor blocker and endothelial function in humans : role of nitric oxide and oxidative stress (review).2005

    • Author(s)
      Higashi Y
    • Journal Title

      CMC-Cardio & Hemato Agents 3

      Pages: 133-148

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Angiotensin II type I receptor blocker and endothelial function in humans : role of nitric oxide and oxidative stress (review).2005

    • Author(s)
      Higashi Y
    • Journal Title

      Current Medicinal Chemistry-Cardiovascular & Hematological Agents

      Pages: 133-148

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Nicorandil-induced vasodilation is, at least in part, due to endothelium-derived hyperpolarizing factor in humans.2005

    • Author(s)
      Ueda K, Higashi Y(他12名, 13番目)
    • Journal Title

      J Cardiovasc Pharm 45

      Pages: 290-294

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production and decrease in reactive oxygen species.2005

    • Author(s)
      Higashi Y(他10名)
    • Journal Title

      Atherosclerosis (In press)

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Effect of Edaravone, A novel free radical scavenger, on endothelium-dependent vasodilation in smokers.2004

    • Author(s)
      Jitsuiki D, Higashi Y(他9名, 2番目)
    • Journal Title

      Am J Cardiol 94

      Pages: 1070-1073

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia.2004

    • Author(s)
      Higashi Y(他12名)
    • Journal Title

      Circulation 109

      Pages: 1215-1218

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Tooth loss is associated with an increased risk of hypertension in postmenopausal women.2004

    • Author(s)
      Taguchi A, Higashi Y(他9名, 10番目)
    • Journal Title

      Hypertension 43

      Pages: 1297-1300

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia2004

    • Author(s)
      Yukihito Higashi
    • Journal Title

      Circulation 109

      Pages: 1215-1218

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390177
  • [Journal Article] Exercise and endothelial function : role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients (review).2004

    • Author(s)
      Higashi Y, Yoshizumi M.
    • Journal Title

      Pharmacology and Therapeutics 102

      Pages: 87-96

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia.2004

    • Author(s)
      Higashi Y
    • Journal Title

      Circulation 109

      Pages: 1215-1218

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Relation between C reactive protein concentrations and coronary microvascular endothelial function.2004

    • Author(s)
      Teragawa H, Higashi Y(他7名, 5番目)
    • Journal Title

      Heart 90

      Pages: 750-754

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Forearm endothelial function and bone mineral loss in postmenopausal women.2004

    • Author(s)
      Sanada M, Higashi Y(他6名, 3番目)
    • Journal Title

      Atherosclerosis 176

      Pages: 387-392

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women.2004

    • Author(s)
      Tsuda M, Higashi Y(他7名, 3番目)
    • Journal Title

      Clin Endoclinol 61

      Pages: 619-625

    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Exercise and endothelial function : role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients (review).2004

    • Author(s)
      Higashi Y
    • Journal Title

      Pharmacology and Therapeutics 102

      Pages: 87-96

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Method for assessing endothelial function in humans using a strain-gauge plethysmography : nitric oxide-dependent and -independent vasodilation(review).2003

    • Author(s)
      Higashi Y
    • Journal Title

      J Pharma Sci 93

      Pages: 399-404

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Method for assessing endothelial function in humans using a strain-gauge plethysmography : nitric oxide-dependent and -independent vasodilation.2003

    • Author(s)
      Higashi Y
    • Journal Title

      J Pharma Sci 93

      Pages: 399-404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans2003

    • Author(s)
      Yukihito Higashi
    • Journal Title

      Journal of American Callege of Cardioligy 42

      Pages: 256-263

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390177
  • [Journal Article] Azelnidipine : a viewpoint by Yukihito Higashi (guest commentaries).2003

    • Author(s)
      Higashi Y
    • Journal Title

      Drugs 63

      Pages: 2623-2624

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Journal Article] Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans : role of nitric oxide and oxidative stress.2003

    • Author(s)
      Higashi Y
    • Journal Title

      J Am Coll Cardiol 42

      Pages: 256-263

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590751
  • [Patent] 慢性腎臓病を処置する装置2018

    • Inventor(s)
      東幸仁、中島歩、相原直樹
    • Industrial Property Rights Holder
      東幸仁、中島歩、相原直樹
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-235405
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K09617
  • [Patent] 血管内皮機能評価装置2011

    • Inventor(s)
      辻敏夫、吉栖正雄、東幸仁、河本昌志、小沢秀夫、鵜川貞二、高柳恒夫、森本陽香、久保諒祐
    • Industrial Property Rights Holder
      日本光電株式会社、国立大学法人広島大学
    • Filing Date
      2011-12-19
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Patent] PGC-1の発現制御装置、並びに虚血性疾患の治療装置及び治療方法2009

    • Inventor(s)
      東幸仁、久保裕嗣、隅田潔、西村嘉博、新実信夫
    • Industrial Property Rights Holder
      国立大学法人広島大学、日本シグマックス株式会社
    • Filing Date
      2009-11-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Patent] 血管壁モニタリング装置、血管壁モニタリング用プログラム及びコンピュター読み込み可能な記録媒体2009

    • Inventor(s)
      辻敏夫、吉栖正雄、河本昌志、東幸仁、佐伯昇、中村隆治、アブドゲニクトュルク、河野曜暢、堀内徹也、鵜川貞二
    • Industrial Property Rights Holder
      日本光電株式会社、国立大学法人広島大学
    • Filing Date
      2009-11-26
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Patent] 血管内皮機能評価装置2009

    • Inventor(s)
      東幸仁
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Number
      2009-212533
    • Filing Date
      2009-09-14
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 血流依存性血管拡張反応とニトログリセリン誘発性血管拡張反応2020

    • Author(s)
      丸橋達也、木原康樹、東幸仁
    • Organizer
      第5回血管不全学会学術集会・総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08404
  • [Presentation] 下顎骨皮質骨の脆弱化と高血圧リスク2019

    • Author(s)
      田口 明,山田真一郎,小日向清美,長内 秀,内田啓一,杉野紀幸,黒岩博子,吉成伸夫,東 幸仁
    • Organizer
      第24回日本歯科放射線学会臨床画像大会
    • Data Source
      KAKENHI-PROJECT-18K09758
  • [Presentation] 強皮症に伴う手指壊疽に対して低周波超音波を用いた1例2018

    • Author(s)
      梶川正人,松井翔吾,丸橋達也,岸本真治,岩本由美子,野間玄督,中島歩,木原康樹,東幸仁
    • Organizer
      第17回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Vascular Function tests and Cardiovascular Risk Prediction in Patients with Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A2018

    • Author(s)
      Maruhashi T, Tomiyama H, Yamashina A, Takase B, Suzuki T, Kihara Y, Higashi Y
    • Organizer
      第82回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Low-Intensity Pulsed Ultrasound Ameliorates Experimental Renal Fibrosis2018

    • Author(s)
      Aibara Y, Nakashima A, Higashi Y
    • Organizer
      The 2nd International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09617
  • [Presentation] Impairment of Endothelial Function in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level: FMD-J Study2018

    • Author(s)
      Maruhashi T, Higashi Y, Iwamoto Y, Kajikawa M, Kishimoto S, Matsui S, Hashimoto H, Hidaka T, Noma K, Tomiyama H, Takase B, Yamashina A, Kihara Y
    • Organizer
      第82回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Patients with Diastolic Ventricular Dysfunction and Ventricular Hypertrophy may occur Heart Failure with Preserved Ejection Fraction through Endothelial Dysfunction2018

    • Author(s)
      Kishimoto S, Higashi Y, Maruhashi T, Kajikawa M,Matsui S, Hashimoto H, Hidaka T, Noma K, Kihara Y
    • Organizer
      第82回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Effect of Coffee with a High Content of Chlorogenic Acids and Low Content of Hydroxyhydroquinone on Postprandial Endothelial Dysfunction2017

    • Author(s)
      Kajikawa M, Maruhashi T, Hidaka T, Nakano Y, Kurisu S, Matsumoto T, Iwamoto Y, Kishimoto S, Matsui S, Hashimoto H, Farina BMY, Kihara Y, Noma K, Nakashima A, Watanabe T, Tone H, Hibi M, Osaki N, Katsuragi Y, Higashi Y
    • Organizer
      American Heart Association Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Mitral Systolic Velocity at Peak Exercise Predicts Impaired Exercise Capacity in Patients with Heart Failure with Preserved Ejection Fraction2017

    • Author(s)
      Masada K, Hidaka T, Kinoshita M, Higashi A, Utsunomiya H, Kihara Y
    • Organizer
      第81回日本循環器学会学術集会
    • Place of Presentation
      石川県
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 酸化成分低減クロロゲン酸含有コーヒーは食後の血管内皮障害を抑制する2017

    • Author(s)
      梶川正人,丸橋達也,岸本真治,松井翔吾,野間玄督,日髙貴之,栗栖智,中野由紀子,木原康樹,渡辺卓也,刀禰寛,日比壮信,大崎紀子,桂木能久,東幸仁
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 心肺運動負荷試験での呼気終末二酸化炭素分圧測定は平均肺動脈圧の推定に有用である2017

    • Author(s)
      東昭史,土肥由裕,北川知郎,日髙貴之,栗栖智,山本秀也,木原康樹
    • Organizer
      第114回日本内科学会総会・講演会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 歯磨きの時間と頻度に基づく口腔衛生が血管内皮機能に及ぼす影響2017

    • Author(s)
      松井翔吾,梶川正人,丸橋達也,岩本明倫,小田望,岸本真治,日髙貴之,中島歩,野間玄督,木原康樹,東幸仁
    • Organizer
      第2回日本血管不全学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Early Mitral Diastolic Inflow Velocity to Global Longitudinal Strain Ratio is an Independent Predictor of Exercise Capacity in Heart Failure2017

    • Author(s)
      Masada K, Hidaka T, Kinoshita M, Higashi A, Utsunomiya H, Kihara Y
    • Organizer
      第81回日本循環器学会学術集会
    • Place of Presentation
      石川県
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Association Between Exercise Capacity and Invasive Hemodynamics at Rest and During Exercise in Degenerative Mitral Regurgitation2017

    • Author(s)
      Utsunomiya H, Hidaka T, Harada Y, Kinoshita M, Masada K, Higashi A, Kihara Y
    • Organizer
      日本超音波医学会第90回学術集会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 脳心血管障害の予測因子としてのROCK活性2017

    • Author(s)
      野間玄督、梶川正人、木原康樹、東幸仁
    • Organizer
      第49回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09554
  • [Presentation] 突発性アルドステロン症における血管内皮機能とRho-associated kinase活性について2017

    • Author(s)
      岸本真治,松井翔吾,小田望,梶川正人,岩本由美子,丸橋達也,日髙貴之,中島歩,野間玄督,木原康樹,東幸仁
    • Organizer
      第2回日本血管不全学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Vascular function is impaired in subjects with decreased circulating level of pigment epithelium-derived factor2017

    • Author(s)
      Kajikawa M, Higashi Y, Maruhashi T, Iwamoto Y, Oda N, Kishimoto S, Matsui S, Hidaka T, Noma K, Nakashima A, Matsui T, Yamagishi S, Kihara Y
    • Organizer
      American Heart Association Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Endothlial function(FMD/RH-PAT/ezFMD)2017

    • Author(s)
      丸橋達也,木原康樹,東幸仁
    • Organizer
      第49回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 新規血管内皮機能測定装置改良型enclosed zone flow-mediated vasodilation (ezFMD)の有用性2017

    • Author(s)
      梶川正人,森本陽香,松井翔吾,小田望,平野陽豊,丸橋達也,岸本真治,岩本由美子,日髙貴之,中島歩,野間玄督,木原康樹,鵜川貞二,辻敏夫,東幸仁
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 劇症1型糖尿病,糖尿病性ケトアシドーシスを伴った劇症型心筋炎の一例2017

    • Author(s)
      須澤仁,日髙貴之,泉可奈子,橋本東樹,宇都宮裕人,有廣光司,木原康樹
    • Organizer
      第65回日本心臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 血管機能障害・構造異常はHeart failure with preserved ejection fraction(HFpEF)の病因に成り得るか2017

    • Author(s)
      岸本真治,東幸仁,丸橋達也,梶川正人,小田望,松井翔吾,日髙貴之,野間玄督,木原康樹
    • Organizer
      第110回日本循環器病学会中国・四国合同地方会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Impaired endothelial function in patients receiving antihypertensive drug treatment regardless of achieved blood pressure level: FMD-J Study2017

    • Author(s)
      Maruhashi T, Higashi Y, Kajikawa M, Iwamoto Y, Kishimoto S, Matsui S, Hashimoto H, Hidaka T, Noma K, Nakashima A, Kihara Y
    • Organizer
      American Heart Association Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Endothelial function measured by enclosed zone flow-mediated vasodilation predicts cardiovascular events2017

    • Author(s)
      Kajikawa M, Morimoto H, Oda N, Idei N, Hirano H, Maruhashi T, Kishimoto S, Matsui S, Hidaka T, Farina BMY, Kihara Y, Noma K, Nakashima A, Ukawa T, Tsuji T, Higashi Y
    • Organizer
      American Heart Association Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Short Term Colchicine Treatment Improves Endothelial Function in Patients with Cardiovascular Disease2017

    • Author(s)
      Kajikawa M, Kurisu S, Maruhashi T, Hidaka T, Iwamoto Y, Kishimoto S, Matsui S, Hashimoto H, Farina BMY, Kihara Y, Noma K, Nakashima A, Matsushita A, Tomiyama H, Ueda S, Higashi Y
    • Organizer
      American Heart Association Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Optimal Cut-off Level of Low-Density Lipoprotein Cholesterol for Normal Vascular Function in a General Population2017

    • Author(s)
      Matsui S, Higashi Y, Kajikawa M, Maruhashi T, Kishimoto S, Oda N, Hidaka T, Nakashima A, Noma K, Kihara Y
    • Organizer
      European Society of Cardiology 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 心不全患者における収縮能と拡張能両方を併せ持つ新しい心エコー図指標と運動耐容能の関連についての検討2017

    • Author(s)
      政田賢治,日高貴之,原田侑,須澤仁,木下未来,東昭史,宇都宮裕人,木原康樹
    • Organizer
      第28回日本心エコー図学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] FMDの臨床への実践的応用~補助的検査からの脱却~2017

    • Author(s)
      丸橋達也,野間玄督,木原康樹,東幸仁
    • Organizer
      第2回日本血管不全学会学術集会・総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 高血圧症における血管内皮機能障害:FMD-Japan Study2017

    • Author(s)
      梶川正人,丸橋達也,松井翔吾,小田望,岸本真治,野間玄督,木原康樹,冨山博史,高瀬凡平,山科章,東幸仁
    • Organizer
      第2回日本血管不全学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] コレステロールが血管機能に与える影響およびLDLコレステロールの至適目標値:スタチン治療患者とスタチン未治療患者での検討2017

    • Author(s)
      松井翔吾,東幸仁,梶川正人,丸橋達也,橋本東樹,岸本真治,日高貴之,野間玄督,木原康樹
    • Organizer
      第117回日本内科学会中国地方会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 脳心血管障害の予測因子としてのROCK活性2017

    • Author(s)
      野間玄督,梶川正人,木原康樹,東幸仁
    • Organizer
      第49回日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] The Evaluation of Pulmonary Vascular Resistance and Right Ventricular Function by Using Echocardiography.2016

    • Author(s)
      Dohi Y, Uga S, Higashi A, Kinoshita H, Sada Y, Kitagawa T, Hidaka T, Suenari K, Noma K, Fukuda Y, Kurisu S, Nakano Y, Yamamoto H, Higashi Y, Kihara Y.
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2016-03-20
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Impact of Triglycerides as Residual Risk for Cardiovascular Events on Endothelial Function: FMD-Japan Registry2016

    • Author(s)
      Kajikawa M, Maruhashi T, Oda N, Kishimoto S, Matsui S, Hidaka T, Kihara Y, Noma K, Nakashima A, Tomiyama H, Takase B, Yamashina A, Higashi Y
    • Organizer
      Pulse of Asia 2016 Seoul
    • Place of Presentation
      Seoul,Korea
    • Year and Date
      2016-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] ROCK蛋白から斬った動脈硬化症:トランスレーショナル研究2016

    • Author(s)
      野間玄督、丸橋達也、木原康樹、東幸仁
    • Organizer
      日本薬理学会
    • Place of Presentation
      神奈川 (横浜)
    • Year and Date
      2016-03-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461110
  • [Presentation] Extracorporeal Cardiopulmonary Resuscitation in Shockable or Nonshockable Rhythms.2016

    • Author(s)
      Kagawa E, Dote K, Kato M, Sasaki S, Oda N, Nakano Y, Nagai M, Yamane A, Kubo Y, Higashihara T, Miyauchi S, Kihara Y.
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2016-03-20
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Vascular Function and Vascular Structure are Impaired in Patients with Heart Failure with Preserved Ejection Fraction.2016

    • Author(s)
      Kishimoto S, Higashi Y, Oda N, Iwamoto A, Iwamoto Y, Kajikawa M, Maruhashi T, Hidaka T, Nakashima A, Noma K, Kihara Y.
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Vascular Smooth Muscle Function in Coronary and Brachial artery in Patients with Suspected Coroanry Artery Disease2016

    • Author(s)
      Maruhashi T, Kajikawa M, Nakashima A, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Matsui S, Noma K, Kihara Y, Higashi Y
    • Organizer
      Pulse of Asia 2016 Seoul
    • Place of Presentation
      Seoul,Korea
    • Year and Date
      2016-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Right ventricular function derived from echocardiography is strongly related with a right heart-pulmonary system rather than with right ventricular contractility2016

    • Author(s)
      Dohi Y, Higashi A, Ishibashi K, Hidaka T, Kurisu S, Yamamoto H, Kihara Y
    • Organizer
      European Society of Cardiology 2016
    • Place of Presentation
      Roma,Italy
    • Year and Date
      2016-08-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Gender Difference in the Influence of Baseline Brachial Artery Diameter on Flow mediated Vasodilation.2016

    • Author(s)
      Maruhashi T, Higashi Y, Matsui S, Kishimoto S, Oda N, Iwamoto A, Kajikawa M, Iwamoto Y, Hidaka T, Nakashima A, Noma K, Takase B, Tomiyama H, Yamashina A, Kihara Y.
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2016-03-20
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Vascular Function and Intima media Thickness of Leg Artery in Peripheral Artery Disease.2016

    • Author(s)
      Iwamoto A, Higashi Y, Noma K, Nakashima A, Maruhashi T, Kajikawa M, Oda N, Kishimoto S, Iwamoto Y, Hidaka T, Kihara Y.
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2016-03-20
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Endothelial Function Is Impaired in Subjects with Decreased Frequency and Duration of Tooth Brushing2016

    • Author(s)
      Matsui S, Higashi Y, Kajikawa M, Maruhashi T, Iwamoto A, Oda N, Kishimoto S, Hidaka T, Aibara Y, Nakashima A, Noma K, Kihara Y
    • Organizer
      Pulse of Asia 2016 Seoul
    • Place of Presentation
      Seoul,Korea
    • Year and Date
      2016-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Vascular Function and Rho-associated Kinase Activity in Patients with Idiopathic hyperaldosteronism2016

    • Author(s)
      Kishimoto S, Higashi Y,Maruhashi T, Kajikawa M, Nakashima A, Iwamoto Y, Iwamoto A, Oda N, Matsui S, Hidaka T, Aibara Y, Noma K, Kihara Y
    • Organizer
      Pulse of Asia 2016 Seoul
    • Place of Presentation
      Seoul,Korea
    • Year and Date
      2016-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Long-term outcomes of patients treated with unplanned venoarterial extracorporeal membrane oxygenation2016

    • Author(s)
      Kagawa E, Dote K, Kato M, Sasaki S, Oda N, Nakano Y, Nagai M, Yamane A, Kubo Y, Higashihara T, Miyauchi S, Kihara Y
    • Organizer
      European Society of Cardiology 2016
    • Place of Presentation
      Roma,Italy
    • Year and Date
      2016-08-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Endothelial Function is Impaired in Subjects with Increased Serum Triglyceride Levels.2016

    • Author(s)
      Kajikawa M, Higashi Y, Maruhashi T, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Hidaka T, Nakashima A, Noma K, Tomiyama H, Takase B, Yamashina A, Kihara Y.
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2016-03-19
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] A Significant Correlation Between Nitroglycerine-induced Vasodilation in Coronary and Brachial Arteries2016

    • Author(s)
      Maruhashi T, Higashi Y, Kajikawa M, Nakashima A, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Matsui S, Higaki T, Shimonaga T, Watanabe N, Ikenaga H, Hidaka T, Aibara Y, Noma K, Kihara Y
    • Organizer
      American Heart Association 2016
    • Place of Presentation
      New Orleans,USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Associations of number of teeth present with dental panoramic radiography measure in Japanese men and women 40 years and older: a cross-sectional study2016

    • Author(s)
      Tagcuhi A, Takahashi M, Uchida K, Yamada S, Sugino N, Higashi Y, Yamada K
    • Organizer
      International Congress of Osteoporosis 2016
    • Place of Presentation
      Grand Hilton Hotel Seoul(Korea)
    • Year and Date
      2016-11-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11092
  • [Presentation] ROCKをターゲットとした心肥大 / 心疾患における治療戦略2016

    • Author(s)
      野間玄督、木原康樹、東幸仁
    • Organizer
      第2回J-ISCP (国際心血管薬物療法学会 日本部会)
    • Place of Presentation
      徳島
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461110
  • [Presentation] Light to moderate alcohol consumption does not alter endothelial function2016

    • Author(s)
      Oda N, Higashi Y, Maruhashi T, Kajikawa M, Kishimoto S, Matsui S, Iwamoto Y, Hidaka T, Nakashima A, Noma K, Tomiyama H, Takase B, Yamashina A, Kihara Y
    • Organizer
      American Heart Association 2016
    • Place of Presentation
      New Orleans,USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 時計遺伝子によるNa/K-ATPaseβ1を介した血圧日内変動の調節2015

    • Author(s)
      中島歩、正木崇生、土井盛博、東幸仁、加藤幸夫
    • Organizer
      日本腎臓学会
    • Place of Presentation
      名古屋:名古屋国際会議場
    • Year and Date
      2015-06-06
    • Data Source
      KAKENHI-PROJECT-25461248
  • [Presentation] Subpopulations of Regulatory T Cells Abnormalities in Pulmonary Arterial Hypertension.2015

    • Author(s)
      Sada Y, Uga S, Higashi A, Kinoshita H, Dohi Y, Kihara Y.
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2015-04-26
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Vascular Function and Vascular Structure are impaired in Patients With Heart Failure With Preserved Ejection Fraction.2015

    • Author(s)
      Kishimoto S, Higashi Y, Noma K, Nakashima A, Hidaka T, Maruhashi T, Kajikawa M, Iwamoto Y, Iwamoto A, Oda N, Aibara Y, Kihara Y.
    • Organizer
      The 88th Scientific Sessions of the American Heart Association 2015
    • Place of Presentation
      Orlando,USA
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] 外因性NOはROCK活性の抑制を介して心血管疾患を制御する:トランスレーショナル研究2015

    • Author(s)
      野間玄督、丸橋達也、木原康樹、東幸仁
    • Organizer
      第51回高血圧関連疾患モデル学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-10-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461110
  • [Presentation] Resting Periodic Breathing before Cardiopulmonary Exercise Testing was Strongly Correlated with Future Cardiovascular Events in Heart Failure Patients.2015

    • Author(s)
      Kinoshita H, Dohi Y, Uga S, Higashi A, Sada Y, Tokuyama T, Maruhashi T, Kisaka T, Ishibashi K, Kitagawa T, Hidaka T, Fukuda Y, Kurisu S, Nakano Y, Yamamoto H, Kihara Y.
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Influence of Endothelial Function and Rho-Associated Kinase Activity in Patients With Primary Aldosteronism.2015

    • Author(s)
      Matsumoto T(Hiroshima Univ), Higashi Y, Iwamoto A, Kajikawa M, Oda N, Maruhashi T, Nakashima A, Noma K, Kihara Y.
    • Organizer
      The 88th Scientific Sessions of the American Heart Association 2015
    • Place of Presentation
      Orlando,USA
    • Year and Date
      2015-11-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Endothelial Function is Impaired in Relation to Alcohol Consumption in Men in a Large General Population.2015

    • Author(s)
      Oda N, Higashi Y, Kajikawa M, Maruhashi T, Iwamoto A, Kishimoto S, Hidaka T, Nakashima A, Noma K, Tomiyama H, Takase B, Yamashina A, Kihara Y.
    • Organizer
      The 88th Scientific Sessions of the American Heart Association 2015
    • Place of Presentation
      Orlando,USA
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Endothelial Function is Impaired in Subjects With Increased Ratio of Serum Levels of AGEs to Soluble Form of RAGE.2015

    • Author(s)
      Kajikawa M, Higashi Y, Nakashima A, Fujimura N, Maruhashi T, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Hidaka T, Noma K, Takeuchi M, Matsui T, Yamagishi S, Kihara Y.
    • Organizer
      The 88th Scientific Sessions of the American Heart Association 2015
    • Place of Presentation
      Orlando,USA
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Increased Triglyceride Levels are Associated With Endothelial Dysfunction: FMD-Japan Registry.2015

    • Author(s)
      Kajikawa M, Higashi Y, Maruhashi T, Iwamoto Y, Iwamoto A, Oda N, Kishimoto S, Hidaka T, Noma K, Tomiyama T, Takase B, Yamashina A, Kihara Y.
    • Organizer
      The 88th Scientific Sessions of the American Heart Association 2015
    • Place of Presentation
      Orlando,USA
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09084
  • [Presentation] Role of ROCK in sustained vasoconstriction in patients with essential hypertension2014

    • Author(s)
      Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
    • Organizer
      The 18^<th> International Vascular Biology Meeting (IVBM2014)
    • Place of Presentation
      京都,日本
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] ROCK as a modulator of sustained vasoconstriction of resistance artery in patients with essential hypertension2014

    • Author(s)
      Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
    • Organizer
      第78回日本循環器学会総会・学術集会
    • Place of Presentation
      東京,日本
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Destabilization of eNOS mRNA via ROCK2-mediated eEF1A1 phosphorylation.2014

    • Author(s)
      野間玄督, 木原康樹, 東 幸仁.
    • Organizer
      第3回臨床高血圧フォーラム
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] ROCK Activity and Endothelial Function: Potential Candidates for Vascular and Anti-aging Biomarkers2014

    • Author(s)
      野間玄督, 木原康樹, 東 幸仁.
    • Organizer
      第14回日本抗加齢医学会総会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Clinical Impact of ROCK in Sustained Vasoconstriction in Patients with Essential Hypertension.2014

    • Author(s)
      Noma K, Goto C, Kihara Y, Higashi Y.
    • Organizer
      第35回日本循環制御医学会総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] ROCK as a Modulator of Sustained Vasoconstriction of ResistanceArtery in Patients with Essential Hypertension.2014

    • Author(s)
      Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
    • Organizer
      第78回日本循環器学会総会・学術集会.
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Destabilization of eNOS mRNA via ROCK2-mediated eEF1A1 phospohrylation2014

    • Author(s)
      野間玄督,木原康樹,東幸仁
    • Organizer
      第3回臨床高血圧フォーラム
    • Place of Presentation
      広島,日本
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Role of ROCK in Sustained Arterial Vasoconstriction in Patients with Essential Hypertension.2014

    • Author(s)
      Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
    • Organizer
      The 18th International Vascular Biology Meeting (IVBM 2014)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Role of ROCK in Sustained Vasoconstriction of Resistance Artery in Patients with Essential Hypertension.2013

    • Author(s)
      Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
    • Organizer
      Scientific Sessions 2013, American Heart Association.
    • Place of Presentation
      Dallas, USA
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Clinical Evaluation of Endothelial Function and Dysfunction2013

    • Author(s)
      野間玄督, 木原康樹, 東 幸仁.
    • Organizer
      第35回EMBC学術集会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Regulation of eNOS mRNA stability via ROCK2-mediated eEF1A1 phosphorylation.2013

    • Author(s)
      野間玄督、木原康樹、東幸仁
    • Organizer
      第21回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Role of ROCK in sustained vasoconstriction of resistance artery in patients with essential hypertension2013

    • Author(s)
      Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
    • Organizer
      Scientific Sessions 2013, American Heart Association
    • Place of Presentation
      Dallas, USA
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Regulation of eNOS mRNA stability via ROCK2-mediated eEF1A1 phosphorylation2013

    • Author(s)
      野間玄督、木原康樹、東幸仁
    • Organizer
      第21回日本血管生物医学会学術集会
    • Place of Presentation
      大阪,日本
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Assessment for Endothelial Function : Flow-mediated vasodilation (FMD)2012

    • Author(s)
      東幸仁
    • Organizer
      第76回日本循環器学会総会
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Assessment for Endothelial Function : Flow-mediated vasodilation(FMD)2012

    • Author(s)
      Yukihito Higashi
    • Organizer
      第76回日本循環器学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] ROCK関連研究の新たな展開2012

    • Author(s)
      野間玄督, 東幸仁
    • Organizer
      第41回日本心脈管作動物質学会(招待講演)
    • Place of Presentation
      秋田
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Role of ROCK in sustained vasoconstriction in patients with essential hypertension.2012

    • Author(s)
      野間玄督, 東幸仁
    • Organizer
      第8回宮崎サイエンスキャンプ
    • Place of Presentation
      宮崎
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] ROCK関連研究の新たな展開2012

    • Author(s)
      野間玄督,東幸仁
    • Organizer
      第41回日本心脈管作動物質学会
    • Place of Presentation
      秋田,日本
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] 内皮機能評価:その実際と意義2011

    • Author(s)
      東幸仁
    • Organizer
      第59回日本心臓病学会
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Association of tooth loss with silent lacunar infarction2011

    • Author(s)
      Taguchi A, Miki M, Migita K, Higashi Y, Yoshinari N
    • Organizer
      IADR/AADR/CADR 89^<th> General Session and Exhibition
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-03-18
    • Data Source
      KAKENHI-PROJECT-21592404
  • [Presentation] 歯周病と血管内皮機能2011

    • Author(s)
      東幸仁
    • Organizer
      第54回日本歯周病学会
    • Place of Presentation
      下関(招待講演)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 血管内皮機能を捉える2011

    • Author(s)
      東幸仁
    • Organizer
      第11回動脈硬化学会教育フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2011-02-06
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Leukocyte ROCK activity : a potential candidate for vascular and anti-aging biomarker2011

    • Author(s)
      野間玄督,木原康樹,東幸仁
    • Organizer
      アンチエイジングフェスタ2011
    • Place of Presentation
      大阪,日本
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] Rho-Associated Kinase(ROCK) Activity and Left Ventricular Hypertrophy in Patients with Essential Hypertension2011

    • Author(s)
      Shinsuke Mikami, Yukihito Higashi, Yuichi Fujii, Naomi Idei, Noritaka Fujimura, Takayuki Hidaka, Tatsuya Maruhashi, Yumiko Iwamoto, Yasuki Kihara
    • Organizer
      80^<th> Scientific Sessions, American Heart Association
    • Place of Presentation
      Orlando, FA. USA
    • Year and Date
      2011-11-14
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 内皮機能評価:その実際と意義2011

    • Author(s)
      東幸仁
    • Organizer
      第59回日本心臓病学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Effects of Selective Mineralocorticoid Receptor Blocker Eplerenone on Endothelial Functionand the Activity of Rho-Associated Kinase in Patients with Essential Hypertension2011

    • Author(s)
      Noritaka Fujimura, Yukihito Higashi, Yumiko Iwamoto, Tatsuya Maruhashi, Shinsuke Mikami, Naomi Idei, Takayuki Hidaka, Kensuke Noma, James K Liao, Yasuki Kihara
    • Organizer
      80^<th> Scientific Sessions, American Heart Association
    • Place of Presentation
      Orlando, FA. USA
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Panoramic radiography measure and silent lacunar infarction2011

    • Author(s)
      Taguchi A, Miki M, Migita K, Higashi Y, Yoshinari N
    • Organizer
      The 18^<th> International Congress of Dento-maxillofacial Radiology
    • Place of Presentation
      Hiroshima, Japan
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-PROJECT-21592404
  • [Presentation] 心血管疾患におけるROCK活性:メディエーターそしてマーカーとしての役割2011

    • Author(s)
      野間玄督, 東幸仁, 木原康樹
    • Organizer
      第19回日本血管生物医学会学術集会(招待講演)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] FMD測定とNADPH oxidase欠損症患者からの教訓2011

    • Author(s)
      東幸仁
    • Organizer
      第11回日本NO学会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-05-14
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] FMD測定とNADPH oxidase欠損症患者からの教訓2011

    • Author(s)
      東幸仁
    • Organizer
      第11回日本NO学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-14
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 歯周病と血管内皮機能2011

    • Author(s)
      東幸仁
    • Organizer
      第54回日本歯周病学会
    • Place of Presentation
      下関
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 心臓が動脈・血管に与える影響(FMD):心不全とFMD2011

    • Author(s)
      東幸仁
    • Organizer
      第84回日本超音波学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Leukocyte ROCK Activity: a Potential Candidate for Vascular and Anti-aging Biomarker.2011

    • Author(s)
      野間玄督, 木原康樹, 東幸仁
    • Organizer
      アンチエイジングフェスタ2011
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] How to MeasureEndothelial Function in Patients with Hypertension : from Plethysmograhy, FMD, and Biomarkers to a New Device2011

    • Author(s)
      Yukihito Higashi
    • Organizer
      第75回日本循環器学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-19
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 心臓が動脈・血管に与える影響(FMD):心不全とFMD2011

    • Author(s)
      東幸仁
    • Organizer
      第84回日本超音波学会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 心血管疾患におけるROCK活性:メディエーターそしてマーカーとしての役割2011

    • Author(s)
      野間玄督,東幸仁,木原康樹
    • Organizer
      第19回日本血管生物医学会学術集会
    • Place of Presentation
      東京,日本
    • Data Source
      KAKENHI-PROJECT-23591043
  • [Presentation] 血管内皮機能はどう臨床に応用するか?2010

    • Author(s)
      東幸仁
    • Organizer
      日本動脈硬化学会・診断技術向上セミナー
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Role of Endothelial Function in Atherosclerosis. The 18th Annual Meeting of the JapaneseVascular Biology and Medicine Organization2010

    • Author(s)
      Yukihito Higashi
    • Organizer
      The 8^<th> Korea-JapanJoint Symposium on Vascular Biology
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 血管内皮機能Up to Date2010

    • Author(s)
      東幸仁
    • Organizer
      日本心エコー図学会
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2010-07-25
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 重症末梢血管疾患における細胞治療による血管再生の長期予後と今後の課題2010

    • Author(s)
      東幸仁
    • Organizer
      日本再生医療学会
    • Place of Presentation
      広島
    • Year and Date
      2010-03-18
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Endothelial Function and Oxidative Stress in X-Linked, gp91phox Deficiency2010

    • Author(s)
      Yukihito Higashi, Junko Soga, Noritaka Fujimura, Masao Kobayash
    • Organizer
      Chronic GranulomatousDisease. 79th Scientific Sessions
    • Place of Presentation
      Chicago, IL. USA
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Role of Endothelial Function in Atherosclerosis2010

    • Author(s)
      Yukihito Higashi
    • Organizer
      日本血管生物医学会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 血管内皮機能の役割2010

    • Author(s)
      東幸仁
    • Organizer
      日本臨床スポーツ医学会
    • Place of Presentation
      筑波(招待講演)
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Oxidative Stressand NO in Cardiovascular Disease2010

    • Author(s)
      Yukihito Higashi
    • Organizer
      The 10^<th> International Conference on theBiology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Oxidative Stress and NO in Cardiovascular Disease.2010

    • Author(s)
      Yukihito Higashi
    • Organizer
      International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Latest Methods to Evaluate Endothelial Function2010

    • Author(s)
      Kensuke Noma, Yasuki Kihara, Masao Yoshizumi, Yukihito Higashi
    • Organizer
      日本循環器学会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-09
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Pharmacological Therapy for Peripheral Arterial Disease : from Platelet Function to Endothelial Function2009

    • Author(s)
      東幸仁
    • Organizer
      日本心臓リハビリテーション学会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 血管機能2009

    • Author(s)
      東幸仁
    • Organizer
      日本超音波学会
    • Place of Presentation
      東京
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 閉塞性動脈硬化症と血管内皮機能2009

    • Author(s)
      東幸仁
    • Organizer
      日本脈管学会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-29
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Therapeutic Strategy for Peripheral Arterial Disease : Pharmacological Therapy and Angiogenesis. Roles of serotonin andnitric oxide2009

    • Author(s)
      Yukihito Higashi
    • Organizer
      10^<th> International Symposium on Mechanisms on Vasodilation
    • Place of Presentation
      Matsushima, Japan
    • Year and Date
      2009-06-01
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Vascular ROCK activity evaluated by a strain-gauge plethysmography2009

    • Author(s)
      野間玄督, 東幸仁, 吉栖正生
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      山口
    • Year and Date
      2009-07-17
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] Therapeutic Strategy for Peripheral Arterial Disease : Pharmacological Therapy and Angiogenesis -Roles of serotonin and nitric oxide-2009

    • Author(s)
      東幸仁
    • Organizer
      International Symposium on Mechanisms on Vasodilation
    • Place of Presentation
      Matsushima, Japan
    • Year and Date
      2009-06-01
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 加齢と血管内皮機能:NO、血管内皮前駆細胞、酸化ストレスの役割2009

    • Author(s)
      東幸仁
    • Organizer
      日本坑加齢学会
    • Place of Presentation
      東京
    • Year and Date
      2009-05-28
    • Data Source
      KAKENHI-PROJECT-21590898
  • [Presentation] 「高血圧を知る-そのメカニスムと関連因子-」高血圧と動脈硬化を結ぶもの:血管機能2007

    • Author(s)
      東 幸仁
    • Organizer
      日本医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-06
    • Data Source
      KAKENHI-PROJECT-18590815
  • [Presentation] Regulation of eNOS mRNA stability vie ROCK2-mediated phosphorylation of eEF1A

    • Author(s)
      野間玄督,廣井透雄,James K. Liao、,東 幸仁
    • Organizer
      第9回宮崎サイエンスキャンプ
    • Place of Presentation
      宮崎
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591043
  • []

  • []

  • 1.  Nakashima Ayumu (40448262)
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  • 3.  YOSHINARI Nobuo (20231699)
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  • 4.  NOMA KENSUKE (00379893)
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    # of Collaborated Projects: 4 results
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  • 6.  KIHARSA Yasuki (40214853)
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  • 7.  YOSHIZUMI Masao (20282626)
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    # of Collaborated Products: 21 results
  • 8.  丸橋 達也 (10727069)
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  • 9.  KAWAMOTO TAKESHI (50224861)
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  • 10.  KATO Yukio (10112062)
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  • 11.  浅野 晃 (60243987)
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  • 12.  杉野 紀幸 (10460445)
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  • 13.  TSUJI Toshio (90179995)
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  • 29.  田口 隆浩 (70772010)
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  • 40.  SATOH Minoru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  梶川 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 42.  高橋 雅和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  土肥 由裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  鎌田 英明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  浅野 知一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  馬場 隆太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  柏原 直樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  長洲 一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  高瀬 凡平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 50.  中佐 智幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  味八木 茂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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