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SHOJI IKUO  勝二 郁夫

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Shoji Ikuo  勝二 郁夫

SHOJI Ikuo  勝二 郁夫

勝二 郁夫  ショウジ イクオ

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Researcher Number 40356241
Other IDs
Affiliation (Current) 2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 神戸大学, 医学研究科, 教授
2016: 神戸大学, 医学研究科, 教授
2015: 神戸大学, 医学(系)研究科(研究院), 教授
2014: 神戸大学, 大学院医学研究科, 准教授
2012 – 2014: 神戸大学, 医学(系)研究科(研究院), 准教授 … More
2012: 神戸大学, 大学院・医学研究科, 准教授
2010 – 2011: 神戸大学, 医学研究科, 准教授
2008: 神戸大学, 大学院・医学研究科, 准教授 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 49060:Virology-related
Except Principal Investigator
Basic Section 80010:Area studies-related / Gastroenterology / Biological Sciences
Keywords
Principal Investigator
HCV / 肝脂肪化 / 脂肪滴 / 肥大化 / NS3/4A / C型肝炎ウイルス / TIP47 / NS3/4Aプロテアーゼ / SPG20 / ADRP … More / AIP4 / JNK / ウイルス増殖 / 肝癌 / 肝炎 / 脂肪化 / NS3/4A プロテアーゼ / HCV JFH-1 / レプリコン / レポーター / hnRNPF / hnRNPH / コア蛋白質 / 宿主因子 / NS5A蛋白質 / ウイルス産生 / C型肝炎 / 肝臓学 … More
Except Principal Investigator
感染症 / 文理協働 / 移民 / 福祉 / 難民 / 移住 / 開発 / グローバリゼーション / FoxO1 / C型肝炎ウイルス / Bim / アポトーシス / MKP3 / 脱リン酸化 / Fox01 / 糖新生 / C型肝炎ウイルス / 遺伝子 / ウイルス Less
  • Research Projects

    (6 results)
  • Research Products

    (141 results)
  • Co-Researchers

    (26 People)
  •  Molecular mechanism of HCV-induced formation of large lipid droplets and virus life cyclePrincipal Investigator

    • Principal Investigator
      Shoji Ikuo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Kobe University
  •  Cooperation of Humanities and Sciences to Establish an Empirical Research Project for Implementing and Examining "Global Welfare"

    • Principal Investigator
      SAKURAI Tetsu
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 80010:Area studies-related
    • Research Institution
      Kobe University
  •  Molecular mechanism of hepatitis C virus-induced lipid droplet formationPrincipal Investigator

    • Principal Investigator
      SHOJI Ikuo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kobe University
  •  Study on molecular mechanisms of glucose metabolic disorders mediated by hepatitis C virus

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kobe University
  •  The study of molecular mechanism of hepatitis C virusproductionPrincipal Investigator

    • Principal Investigator
      SHOJI Ikuo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kobe University
  •  C型肝炎ウイルスの増殖適応変異と病原性の研究

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University

All 2023 2022 2021 2020 2019 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] The Role of Autophagy in Infectious Diseases2022

    • Author(s)
      Chieko Matsui, Putu Yuliandari, Lin Deng, Takayuki Abe, and Ikuo Shoji,
    • Total Pages
      427
    • Publisher
      Frontiers Research Topics
    • ISBN
      9782832504260
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Book] 最新!C型肝炎治療薬の使いかた. NS5A-IRRDR変異数2012

    • Author(s)
      勝二郁夫
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Book] 最新!C 型肝炎治療薬の使いかた.2012

    • Author(s)
      勝二郁夫
    • Publisher
      診断と治療社, 岡上武監修
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Book] はじめの一歩のイラスト感染症・微生物学(本田武司編)2011

    • Author(s)
      勝二郁夫
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Book] シンプル微生物学(東匡伸、小熊惠二、堀田博編集)2011

    • Author(s)
      勝二郁夫
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Book] はじめの一歩のイラスト感染症・微生物学2011

    • Author(s)
      勝二郁夫
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Book] シンプル微生物学2011

    • Author(s)
      勝二郁夫
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Complete genome analyses of G12P[8] rotavirus strains from hospitalized children in Surabaya, Indonesia, 2017-20182023

    • Author(s)
      Laura Navika Yamani, Takako Utsumi, Yen Hai Doan, Yoshiki Fujii, Zayyin Dinana, Rury Mega Wahyuni, Emily Gunawan, Soegeng Soegijanto, Alpha Fardah Athiyyah, Subijanto Marto Sudarmo, Reza Gunadi Ranuh, Andy Darma, Soetjipto, Juniastuti, Rheza Gandi Bawono, Chieko Matsui, Lin Deng, etc.
    • Journal Title

      Journal of Medical Virology

      Volume: 95 Issue: 2

    • DOI

      10.1002/jmv.28485

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07040, KAKENHI-PROJECT-22K07095, KAKENHI-PROJECT-19H04354, KAKENHI-PROJECT-22K15470
  • [Journal Article] Hepatitis C virus NS5A protein promotes the lysosomal degradation of diacylglycerol O-acyltransferase 1 (DGAT1) via endosomal microautophagy2022

    • Author(s)
      Putu Yuliandari, Chieko Matsui, Lin Deng, Takayuki Abe, Hiroyuki Mori, Shuhei Taguwa, Chikako Ono, Takasuke Fukuhara, Yoshiharu Matsuura, Ikuo Shoji
    • Journal Title

      Autophagy Reports

      Volume: 1 Issue: 1 Pages: 264-285

    • DOI

      10.1080/27694127.2022.2095591

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07040, KAKENHI-PROJECT-22K15470, KAKENHI-PROJECT-19H04354, KAKENHI-PROJECT-20K07514
  • [Journal Article] Hepatitis C Virus-Induced ROS/JNK Signaling Pathway Activates the E3 Ubiquitin Ligase Itch to Promote the Release of HCV Particles via Polyubiquitylation of VPS4A2022

    • Author(s)
      Deng Lin、Liang Yujiao、Ariffianto Adi、Matsui Chieko、Abe Takayuki、Muramatsu Masamichi、Wakita Takaji、Maki Masatoshi、Shibata Hideki、Shoji Ikuo
    • Journal Title

      Journal of Virology

      Volume: 96 Issue: 6 Pages: 1811-21

    • DOI

      10.1128/jvi.01811-21

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-21K07040, KAKENHI-PROJECT-22K15470, KAKENHI-PROJECT-19H04354, KAKENHI-PROJECT-20K07514
  • [Journal Article] The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro2022

    • Author(s)
      Gad Sameh A.、Sugiyama Masaya、Tsuge Masataka、Wakae Kosho、Fukano Kento、Oshima Mizuki、Sureau Camille、Watanabe Noriyuki、Kato Takanobu、Murayama Asako、Li Yingfang、Shoji Ikuo、Shimotohno Kunitada、Chayama Kazuaki、Muramatsu Masamichi、Wakita Takaji、Nozaki Tomoyoshi、Aly Hussein H.
    • Journal Title

      PLOS Pathogens

      Volume: 18 Issue: 3 Pages: 1-26

    • DOI

      10.1371/journal.ppat.1009983

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07586, KAKENHI-PROJECT-19K23855, KAKENHI-PROJECT-21K08006, KAKENHI-PROJECT-19H04354
  • [Journal Article] Molecular epidemiology and genetic diversity of norovirus infection in children hospitalized with acute gastroenteritis in East Java, Indonesia in 2015?20192021

    • Author(s)
      Utsumi Takako、Lusida Maria Inge、Dinana Zayyin、Wahyuni Rury Mega、Soegijanto Soegeng、Soetjipto、Athiyyah Alpha Fardah、Sudarmo Subijanto Marto、Ranuh Reza Gunadi、Darma Andy、Juniastuti、Ishii Koji、Shoji Ikuo et al.
    • Journal Title

      Infection, Genetics and Evolution

      Volume: 88 Pages: 104703-104703

    • DOI

      10.1016/j.meegid.2020.104703

    • NAID

      120006993632

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04354, KAKENHI-PROJECT-21K07040
  • [Journal Article] The Role of Chaperone-Mediated Autophagy in Hepatitis C Virus-Induced Pathogenesis2021

    • Author(s)
      Matsui Chieko、Yuliandari Putu、Deng Lin、Abe Takayuki、Shoji Ikuo
    • Journal Title

      Frontiers in Cellular and Infection Microbiology

      Volume: 11 Pages: 1-8

    • DOI

      10.3389/fcimb.2021.796664

    • NAID

      120007184287

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07514, KAKENHI-PROJECT-21K07040
  • [Journal Article] NS5A-ISGylation via Lysine 26 Has a Critical Role for Efficient Propagation of Hepatitis C Virus Genotype 2a2021

    • Author(s)
      Rheza Gandi Bawono, Takayuki Abe, Yasuaki Shibata, Chieko Matsui, Lin Deng, Ikuo Shoji
    • Journal Title

      Kobe J Med Sci

      Volume: 67

    • NAID

      120007169870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Journal Article] Predominance of norovirus GI.4 from children with acute gastroenteritis in Jambi, Indonesia, 20192020

    • Author(s)
      Wulandari Putri Sari、Juniastuti、Wahyuni Rury Mega、Amin Mochamad、Yamani Laura Navika、Matondang Muhammad Qushai Yunifiar、Dinana Zayyin、Soetjipto、Utsumi Takako、Shoji Ikuo、Lusida Maria Inge
    • Journal Title

      Journal of Medical Virology

      Volume: 92 Issue: 12 Pages: 3165-3172

    • DOI

      10.1002/jmv.26057

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04354
  • [Journal Article] ISGylation of hepatitis C virus NS5A protein promotes viral RNA replication via the recruitment of cyclophilin A2020

    • Author(s)
      Abe T, Minami N, Bawono RG, Matsui C, Deng L, Fukuhara T, Matsuura Y, Shoji I
    • Journal Title

      Journal of Virology

      Volume: 94 Issue: 20 Pages: 1-23

    • DOI

      10.1128/jvi.00532-20

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Journal Article] G2P[4] rotavirus outbreak in Belu, East Nusa Tenggara Province, Indonesia, 20182020

    • Author(s)
      Utsumi Takako、Wahyuni Rury M.、Dinana Zayyin、Gunawan Emily、Putra Arga S.D.、Mubawadi Teguh、Soetjipto、Lusida Maria I.、Shoji Ikuo
    • Journal Title

      Journal of Infection and Public Health

      Volume: 13 Issue: 10 Pages: 1592-1594

    • DOI

      10.1016/j.jiph.2020.05.002

    • NAID

      120006897912

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04354
  • [Journal Article] Post-vaccinated asymptomatic rotavirus infections: A community profile study of children in Surabaya, Indonesia2019

    • Author(s)
      Gunawan Emily、Utsumi Takako、Wahyuni Rury M.、Dinana Zayyin、Sudarmo Subijanto M.、Shoji Ikuo、Soetjipto、Lusida Maria I.
    • Journal Title

      Journal of Infection and Public Health

      Volume: 12 Issue: 5 Pages: 625-629

    • DOI

      10.1016/j.jiph.2019.02.015

    • NAID

      120006733128

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04354
  • [Journal Article] Molecular Epidemiology and Clinical Features of Rotavirus Infection Among Pediatric Patients in East Java, Indonesia During 2015?2018: Dynamic Changes in Rotavirus Genotypes From Equine-Like G3 to Typical Human G1/G32019

    • Author(s)
      Athiyyah Alpha Fardah、Utsumi Takako、Wahyuni Rury Mega、et al.
    • Journal Title

      Frontiers in Microbiology

      Volume: 10

    • DOI

      10.3389/fmicb.2019.00940

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05200, KAKENHI-PROJECT-19H04354
  • [Journal Article] TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis.2016

    • Author(s)
      Aizawa S., Okamoto T., Sugiyama Y., Kouwaki T., Ito A., Suzuki T., Ono C., Fukuhara T., Yamamoto M., Okochi M., Hiraga N., Imamura M., Chayama K., Suzuki R., Shoji I., Moriishi K., Moriya K., Koike K., and Matsuura Y.
    • Journal Title

      Nat. Commun.

      Volume: 7 Issue: 1 Pages: 1-12

    • DOI

      10.1038/ncomms11379

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-26461003
  • [Journal Article] Hepatitis C virus NS5A protein interacts with lysine methyltransferase SET and MYND domain-containing 3 and induces activator protein 1 activation.2016

    • Author(s)
      Chen M, Gan X, Yoshino K, Kitakawa M, Shoji I, Deng L, Hotta H.
    • Journal Title

      Microbiol Immunol.

      Volume: 60 Issue: 6 Pages: 407-417

    • DOI

      10.1111/1348-0421.12383

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460181, KAKENHI-PROJECT-26461003
  • [Journal Article] Physical and functional interaction between hepatitis C virus NS5A protein and ovarian tumor protein deubiquitinase 7B.2015

    • Author(s)
      Sianipar IR, Matsui C, Minami N, Gan X, Deng L, Hotta H, and Shoji I
    • Journal Title

      Microbiology and Immunology

      Volume: 59 Issue: 8 Pages: 466-476

    • DOI

      10.1111/1348-0421.12278

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Journal Article] A single-amino-acid mutation in hepatitis C virus NS5A disrupts physical and functional interaction with the transcription factor HNF-1α.2015

    • Author(s)
      Matsui C, Sianipar I R, Minami N, Deng L, Hotta H, Shoji I
    • Journal Title

      J Gen Virol

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] HCV upregulates Bim through the ROS/JNK signalling pathway, leading to Bax-mediated apoptosis.2015

    • Author(s)
      Deng L, Chen M, Tanaka M, Ku Y, Itoh T, Shoji I, Hotta H
    • Journal Title

      J Gen Virol

      Volume: 96 Issue: 9 Pages: 2670-2683

    • DOI

      10.1099/jgv.0.000221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460181, KAKENHI-PROJECT-26461003
  • [Journal Article] A single-amino-acid mutation in hepatitis C virus NS5A disrupts physical and functional interaction with the transcription factor HNF-1α.2015

    • Author(s)
      Matsui C, Sianipar IR, Minami N, Deng L, Hotta H, and Shoji I.
    • Journal Title

      Journal of General Virology

      Volume: 96 Issue: 8 Pages: 2200-2205

    • DOI

      10.1099/vir.0.000179

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461003, KAKENHI-PROJECT-14J01405
  • [Journal Article] Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species2014

    • Author(s)
      Adianti M, Aoki C, Komoto M, Deng L, Shoji I, Wahyuni TS, Lusida MI, Soetjipto, Fuchino H, Kawahara N, Hotta H
    • Journal Title

      Microbiol Immunol

      Volume: 58(3) Issue: 3 Pages: 180-7

    • DOI

      10.1111/1348-0421.12127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Nitrosative stress induces peroxiredoxin 1 ubiquitination during ischemic insult via E6AP activation in endothelial cells both in vitro and in vivo2014

    • Author(s)
      Tao RR, Wang H, Hong LJ, Huang JY, Lu YM, Liao MH, Ye WF, Lu NN, Zhu DY, Huang Q, Fukunaga K, Lou YJ, Shoji I, Wilcox CS, Lai EY, Han F
    • Journal Title

      Antioxid Redox Signal

      Volume: (in press) Issue: 1 Pages: 1-16

    • DOI

      10.1089/ars.2013.5381

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-26461003
  • [Journal Article] Antiviral activity of extracts from Morinda citrifolia leaves and chlorophyll catabolites, pheophorbide a and pyropheophorbide a, against hepatitis C virus.2014

    • Author(s)
      Ratnoglik SL, Aoki C, Sudarmono P, Komoto M, Deng L, Shoji I, Fuchino H, Kawahara N, Hotta H.
    • Journal Title

      Microbiology and Immunology

      Volume: 58 Issue: 3 Pages: 188-194

    • DOI

      10.1111/1348-0421.12133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.2014

    • Author(s)
      Ratnoglik SL, Jiang DP, Aoki C, Sudarmono P, Shoji I, Deng L, Hotta H
    • Journal Title

      PLoS One

      Volume: 9(6) Issue: 6 Pages: 1-9

    • DOI

      10.1371/journal.pone.0098877

    • NAID

      120005705278

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976, KAKENHI-PROJECT-26461003
  • [Journal Article] Antiviral activities of Indonesian medicinal plants in the East Java region against hepatitis C virus.2013

    • Author(s)
      Wahyuni TS, Tumewu L, Permanasari AA, Apriani E, Adianti M, Rahman A, Widyawaruyanti A, Lusida MI, Fuad A, Soetjipto D, Nasronudin D, Fuchino H, Kawahara N, Shoji I, Deng L, Aoki C, Hotta H.
    • Journal Title

      Virology Journal

      Volume: 10 Issue: 1 Pages: 259-259

    • DOI

      10.1186/1743-422x-10-259

    • NAID

      120005705279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Polymorphisms of the core, NS3 and NS5A proteins of hepatitis C virus genotype 1b associate with development of hepatocellular carcinoma.2013

    • Author(s)
      El-Shamy A, Shindo M, Shoji I, Deng L, Okuno T, Hotta H.
    • Journal Title

      Hepatology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Polymorphisms of hepatitis C virus NS5A and core proteins and clinical outcome of pegylated interferon/ribavirin therapy2012

    • Author(s)
      El-Shamy A, Ide Y-H, Kim SR, Sasase N, Imoto S, Deng L, Shoji I, Hotta H
    • Journal Title

      Inervirology

      Volume: 55 Issue: 1 Pages: 1-11

    • DOI

      10.1159/000322219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Polymorphisms of hepatitis C virus NS5A and core proteins and clinical outcome of pegylated interferon/ribavirin therapy2012

    • Author(s)
      El-Shamy, A., Ide, Y-H., Kim, SR., Sasase, N., Imoto, S., Deng, L., Shoji, I., and Hotta, H.
    • Journal Title

      Intervirology

      Volume: 55 Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] K. HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinases Fyn in B cells2012

    • Author(s)
      Nakashima, K., Takeuchi, K., Chihara, K., Deng, L., Shoji, I., Hotta, H., and Sada
    • Journal Title

      PLoS One

      Volume: 7(10)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Sequence heterogeneity in NS5A of hepatitis C virus genotype 2a and 2b and clinical outcome of pegylated interferon/ribavirin therapy2012

    • Author(s)
      El-Shamy A., Shoji I, Kim SR, Imoto S, Deng L, Yoon S, Fujisawa T, Tani S, Yano Y, Seo Y, Azuma T, Hotta H
    • Journal Title

      PLoS One

      Volume: 55 Issue: 2 Pages: 1-10

    • DOI

      10.1371/journal.pone.0030513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Prediction of response to pegylated interferon/ribavirin combination therapy for chronic hepatitis C genotype 1b and high viral load.2012

    • Author(s)
      Soo Ryang Kim
    • Journal Title

      Journal of Gastroenterology

      Volume: 47 Issue: 10 Pages: 1143-1151

    • DOI

      10.1007/s00535-012-0578-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Generation of a recombinant reporter hepatitis C virus useful for the analyses of virus entry, intra-cellular replication and virion production2012

    • Author(s)
      Kamada, K., Shoji, I., Deng, L, Wakita, T., and Hotta, H
    • Journal Title

      Microbes and Infection

      Volume: 14 Pages: 69-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Molecular mechanism of hepatitis C virus-induced glucose metabolic disorders2012

    • Author(s)
      Shoji, I., Deng L., and Hotta, H
    • Journal Title

      Frontiers in Microbiology

      Volume: 2 Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Hepatitis C virus infection suppresses GLUT2 gene expression via downregulation of hepatocyte nuclear factor 1α.2012

    • Author(s)
      Matsui C
    • Journal Title

      J Virol.

      Volume: 86 Issue: 23 Pages: 12903-12911

    • DOI

      10.1128/jvi.01418-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Polymorphisms of the core, NS3 and NS5A proteins of hepatitis C 1 virus genotype 1b associate with development of hepatocellular carcinoma.2012

    • Author(s)
      Ahmed EL-Shamy
    • Journal Title

      Hepatology

      Volume: - Issue: 2 Pages: 555-563

    • DOI

      10.1002/hep.26205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells.2012

    • Author(s)
      Nakashima, K.
    • Journal Title

      PLoS One

      Volume: 7(10) Issue: 10 Pages: e46634-e46634

    • DOI

      10.1371/journal.pone.0046634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590285, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Roles of the two distinct proteasome pathways in hepatitis C virus infection2012

    • Author(s)
      Shoji, I.
    • Journal Title

      World Journal of Virology

      Volume: 1 Pages: 44-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Roles of the two distinct proteasome pathways in hepatitis C virus infection.2012

    • Author(s)
      Shoji I
    • Journal Title

      World J. Virol.

      Volume: 2 Issue: 2 Pages: 44-50

    • DOI

      10.5501/wjv.v1.i2.44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] NS5A sequence heterogeneity of hepatitis C virus genotype 4a predicts clinical outcome of pegylated-interferon-ribavirin therapy in Egyptian patients.2012

    • Author(s)
      Ahmed EL-Shamy
    • Journal Title

      Journal of Clinical Microbiology

      Volume: 50 Issue: 12 Pages: 3886-3892

    • DOI

      10.1128/jcm.02109-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Hepatitits C virus infection suppresses GLUT2 gene expression via down-regulation of hepatocyte nuclear factor 1α2012

    • Author(s)
      Matsui, C., Shoji, I., Kaneda, S., Sianipar, IR., Deng, L., and Hotta, H
    • Journal Title

      Journal of Virology

      Volume: 86(23) Pages: 12903-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Sequence heterogeneity in NS5A of hepatitis C virus gentypes 2a and 2b and clinical outcome of pegylated-Interferon/Ribavirin therapy2012

    • Author(s)
      El-Shamy, A., Shoji, I., Kim S-R., Ide, Y-H., Imoto, S., Deng, L., Yoon, S., Fujisawa, T., Tani, S., Yano, Y., Seo, Y., Azuma, T., and Hotta, H
    • Journal Title

      PLoS One

      Volume: 7 Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] A point mutation at Asn-534 that disrupts a conserved N-glycosylation motif of the E2 glycoprotein of hepatitis C virus markedly enhances the sensitivity to antibody neutralization2012

    • Author(s)
      Sasayama M., Shoji I., Ide Y-H., Deng L., Hotta H
    • Journal Title

      Journal of Medical Virology

      Volume: 84 Issue: 2 Pages: 229-234

    • DOI

      10.1002/jmv.22257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] A point mutation at Asn-534 that disrupts a conserved N-glycosylation motif of the E2 glycoprotein of hepatitis C virus markedly enhances the sensitivity to antibody neutralization.2012

    • Author(s)
      Sasayama, M., Shoji, I., Adianti M, Jiang DP, Deng, L, Saito T, Watanabe H, Kawata S, Aoki C, and Hotta, H
    • Journal Title

      Journal of Medical Virology

      Volume: 84 Pages: 229-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein.2011

    • Author(s)
      Inoue, Y., Aizaki, H., Hara, H., Matsuda, M., Ando, T., Shimoji, T., Murakami, K., Masaki, T., Shoji, I., Homma, S., Matsuura, Y., Miyamura, T., Lai, MMC, Wakita, T., Suzuki, T.
    • Journal Title

      Virology

      Volume: 410 Pages: 38-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway2011

    • Author(s)
      Deng, L.
    • Journal Title

      J.Virol.

      Volume: 85 Issue: 17 Pages: 8556-8568

    • DOI

      10.1128/jvi.00146-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway2011

    • Author(s)
      Deng, L., Shoji, I., Oawa, W., Kaneda, S., Soga, T., Jiang, D. P., Ide, Y-H., and Hotta, H
    • Journal Title

      Journal of Virology

      Volume: 85 Pages: 8556-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein2011

    • Author(s)
      Inoue, Y., Aizaki, H., Hara, H., Matsuda, M., Ando, T., Shimoji, T., Murakami, K., Masaki, T., Shoji, I., Homma, S., Matsuura, Y., Miyamura, T., Lai, MMC, Wakita, T., and Suzuki, T
    • Journal Title

      Virology

      Volume: 410 Pages: 38-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Potential therapeutic application of intravenous bone marrow infusion in patients with alcoholic liver cirrhosis2011

    • Author(s)
      Saito T, Okumoto K, Haga H, Nishise Y, Ishii R, Sato C, Watanabe H, Okada A, Ikeda M, Togashi H, Ishikawa T, Terai S, Sakaida I, Kawata S
    • Journal Title

      Stem Cells Dev

      Volume: 20 Issue: 6 Pages: 1503-1510

    • DOI

      10.1111/j.1348-0421.2011.00331.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590824, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to Pegylated-Interferon/Ribavirin combination therapy2011

    • Author(s)
      El-Shamy, A., Shoji, I., Saito, T., Watanabe H., Ide, Y-H., Deng, L., Kawata, S., and Hotta, H.
    • Journal Title

      Microbiology and Immunology

      Volume: 55 Pages: 418-26

    • NAID

      10031121486

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Involvement of PA28γ in the propagation of hepatitis C virus2010

    • Author(s)
      Moriishi K., Shoji, I., Mori, Y., Suzuki, R., Suzuki, T., Kataoka, C., and Matsuura, Y
    • Journal Title

      Hepatology

      Volume: 52 Pages: 411-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] 17β-Estradiol inhibits the production of infectious particles of hepatitis C virus.2010

    • Author(s)
      Hayashida K, Shoji, I., Deng, L., Ide, Y-H., Hotta, H.
    • Journal Title

      Microbiology and Immunology

      Volume: 54 Pages: 684-690

    • NAID

      10029546273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Estradiol inhibits the production of infectious particles of hepatitis C virus2010

    • Author(s)
      Hayashida K, Shoji, I., Deng, L., Ide, Y-H., and Hotta, H. 17
    • Journal Title

      Microbiology and Immunology

      Volume: 54 Pages: 684-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Secondary structure of the amino-terminal region of HCV NS3 and virological response to pegylated interferon plus ribavirin therapy for chronic hepatitis C2010

    • Author(s)
      Sanjo M., Saito, T., Ishii, R., Nishise, Y., Haga, H., Okumoto, K., Ito, J., Watanabe, H., Saito, K., Togashi, H., Fukuda, K., Imai, Y., El-Shamy, A., Deng, L., Shoji, I., Hak, H., and Kawata, S
    • Journal Title

      Journal of Medical Virology

      Volume: 82 Pages: 1364-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] E6AP ubiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 12010

    • Author(s)
      Nasu, J., Murakami, K., Miyagawa, S., Yamashita, R., Ichimura, T., Wakita, T., Hotta, H., Miyamura, T., Suzuki, T., Satoh, T., and Shoji, I.
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: 111 Pages: 676-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Involvement of PA28γ in the propagation of hepatitis C virus.2010

    • Author(s)
      Moriishi K., Shoji, I., Mori, Y., Suzuki, R., Suzuki, T., Kataoka, C., Matsuura, Y.
    • Journal Title

      Hepatology

      Volume: 52 Pages: 411-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Secondary structure of the amino-terminal region of HCV NS3 and virological response to pegylated interferon plus ribavirin therapy for chronic hepatitis C.2010

    • Author(s)
      Sanjo M., Saito, T., Ishii, R, Nishise, Y, Haga, H., Okumoto, K., Ito, J., Watanabe, H., Saito, K., Togashi, H., Fukuda, K., Imai, Y, El-Shamy, A., Deng, L., Shoji, I., Hotta, H., Kawata, S.
    • Journal Title

      Journal of Medical Virology

      Volume: 82 Pages: 1364-1370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] E6AP ubiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 1.2010

    • Author(s)
      Nasu, J., Murakami, K., Miyagawa, S., Yamashita, R., Ichimura, T., Wakita, T., Hotta, H., Miyamura, T., Suzuki, T., Satoh, T., Shoji, I.
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: 111 Pages: 676-685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Changes in the distribution of genotype constellations of rotavirus strain after rotavirus vaccine introduction in Asian and African countries2022

    • Author(s)
      Doan YH, Takemae N, Suzuki T, Dennis FE, Armah GE, Utsumi T, Shoji I, Yamani LN, Lusida MI, Miyoshi S, Sarkar MC, Haga K, Fujii Y, Shimizu H, Oka T, Muramatsu M, Kageyama T, Katayama K.
    • Organizer
      日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H04354
  • [Presentation] HCV感染はANX5とPKC-etaによるoccludinの機能制御に干渉することでウイルス伝播を促進させる2022

    • Author(s)
      阿部隆之、松井千絵子、鄧琳、松浦善治、勝二郁夫
    • Organizer
      日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H04354
  • [Presentation] HCV感染はANX5とPKC-etaによるoccludinの機能制御に干渉することでウイルス伝播を促進させる2022

    • Author(s)
      阿部隆之、松井千絵子、鄧琳、松浦善治、勝二郁夫
    • Organizer
      第69回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Presentation] C型肝炎ウイルスが誘導する新規選択的蛋白質分解経路.2022

    • Author(s)
      松井千絵子、Putu Yuliandari, Maria Alethea Septianastiti, 鄧琳, 阿部隆之, 勝二郁夫.
    • Organizer
      第69回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Presentation] HCV感染はANX5とPKC-etaによるoccludinの機能制御に干渉することでウイルス伝播を促進させる2022

    • Author(s)
      阿部隆之、松井千絵子、鄧琳、松浦善治、勝二郁夫
    • Organizer
      第69回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H04354
  • [Presentation] HCV NS3/4A protease cleaves SPG20 for formation of large lipid droplets2021

    • Author(s)
      Matsui C, Yuliandari P, Deng L, Abe T, Shoji I.
    • Organizer
      第68回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Presentation] HCV NS3/4A protease cleaves SPG20 for formation of large lipid droplets2021

    • Author(s)
      Matsui C, Yuliandari P, Deng L, Abe T, Shoji I.
    • Organizer
      27th International symposium on hepatitis C virus and related viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Presentation] Hepatitis C virus infection promotes the lysosomal degradation of Diacylglycerol O-acytransferase 1 (DGAT1).2021

    • Author(s)
      Yuliandari P, Matsui C, Deng L, Abe T, Shoji I.
    • Organizer
      27th International symposium on hepatitis C virus and related viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Presentation] Hepatitis C virus NS3/4A protease specifically cleaves SPG20 and promotes the formation of large lipid droplets2020

    • Author(s)
      Chieko Matsui, Putu Yuliandari, Lin Deng, Takayuki Abe and Ikuo Shoji
    • Organizer
      第43回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Presentation] Hepatitis C Virus infection Promotes the Lysosomal Degradation of Diacylglycerol O-acyltransferase 1 (DGAT1)2020

    • Author(s)
      Putu Yuliandari, Chieko Matsui, Lin Deng, Takayuki Abe, Ikuo Shoji
    • Organizer
      第43回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K07514
  • [Presentation] C型肝炎ウイルス基礎研究の最近の話題2016

    • Author(s)
      勝二郁夫
    • Organizer
      第11回神戸肝疾患治療研究会
    • Place of Presentation
      神戸
    • Year and Date
      2016-02-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Presentation] Molecular mechanism of HCV-induced lysosomal degradation of HNF-1α protein2016

    • Author(s)
      Matsui C, Minami N, Deng L, Shoji I
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌、札幌コンベンションセンター
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Presentation] Molecular mechanism of HCV-induced lysosomal degradation of HNF-1α protein.2016

    • Author(s)
      Matsui C, Minami N, Deng L, and Shoji I.
    • Organizer
      The 23rd International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      京都、国立京都国際会館
    • Year and Date
      2016-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Presentation] Physical and functional interaction between hepatitis C virus NS5A protein and ovarian tumor protein deubiquitinase 7B2015

    • Author(s)
      Imelda R Sianipar, Chieko Matsui, Nanae Minami, Ming Chen, Xiang Gan, Lin Deng, Hak Hotta, Ikuo Shoji
    • Organizer
      22th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Strasbourg, France
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Presentation] A novel pathway for lipid droplet formation induced by hepatitis C virus2015

    • Author(s)
      Chieko Matsui, Imelda Rosalyn Sianipar, Nanae Minami, Ming Chen, Lin Deng, Hak Hotta, Ikuo Shoji
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      博多
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Presentation] C型肝炎ウイルスとプロテアソーム経路2015

    • Author(s)
      勝二郁夫
    • Organizer
      第21回大阪府立母子保健総合医療センターシンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2015-02-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Presentation] C型肝炎ウイルス研究の新展開2014

    • Author(s)
      勝二郁夫
    • Organizer
      千里ライフサイエンスセミナー 免疫・感染症シリーズ第5回「話題のウイルス感染症の正体とその対策」
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461003
  • [Presentation] HCV感染による糖代謝障害の分子機序2013

    • Author(s)
      勝二郁夫、松井千絵子、DENG Lin、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析2013

    • Author(s)
      DENG Lin、陳明、勝二郁夫、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Development of a prophylactic and therapeutic vaccine against Hepatitis C virus2013

    • Author(s)
      Suratno Lulut Ratnoglik, Dapeng Jiang, Chie Aoki, Pratiwi Sudarmono, Lin Deng, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Regulation of hepatocyte nuclear factor 1α by hepatitis C virus NS5A protein2013

    • Author(s)
      Chieko Matsui, Ikuo Shoji, Nanae Minami, Imelda Rosalyn Sianipar, Lin Deng, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5AとHepatocyte nuclear factor (HNF) -1αの相互作用と病態生理2013

    • Author(s)
      松井千絵子、勝二郁夫、南奈苗、Sianipar Imelda Rosalyn、 DENG Lin、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるSmad1/Smad5経路の脱制御とその分子機序について2013

    • Author(s)
      松岡陽子、朝日朱美、Deng Lin、勝二郁夫、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A interacts with SMYD3 and upregulates SMYD3-mediated expression of AGR3 mRNA2013

    • Author(s)
      Ming Chen, Xiang Gan, Lin Deng, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV upregulates Bim through ROS/JNK signaling pathway leading to Bax-mediated apoptosis2013

    • Author(s)
      Lin Deng, Ming Chen, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Antiviral activity of chlorophyll derivatives, pheophorbide a, chlorin e6 and mono-L-aspartyl chlorin e6 (NPe6), against hepatitis C virus2013

    • Author(s)
      Hak Hotta, Chie Aoki, Suratno Lulut Ratnoglik, Pratiwi Sudarmono, Mari Komoto, Lin Deng, Ikuo Shoji, Hiroyuki Fuchino, Nobuo Kawahara
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Development of therapeutic and preventive vaccines against Hepatitis C virus.2012

    • Author(s)
      Jiang DP, Ratnoglik S L, Aoki C, Deng L, Shoji I, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Up-regulation of MAPK phosphatase 3 is involved in HCV-induced suppression of FoxO1 phosphorylation.2012

    • Author(s)
      Deng L, Chen M, Jiang DP, Shoji I, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Molecular mechanism of hepatitis C virus-induced glucose metabolism disorder2012

    • Author(s)
      Ikuo Shoji
    • Organizer
      The 10th JSH Single Topic Conference
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析2012

    • Author(s)
      DENG Lin、勝二郁夫、堀田博
    • Organizer
      第65回日本細菌学会関西支部総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C 型肝炎ウイルスNS5A 蛋白質のSrc homology 2/3 ドメイン結合能とB 細胞での発現によるSrc ファミリーキナーゼFyn の活性化2012

    • Author(s)
      中島 謙治,竹内 健司,千原 一泰,堀口 朋子,孫 雪東, Deng Lin,勝二 郁夫,堀田 博,定 清直
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルスNS5A蛋白質の新規結合因子ヒストンメチル基転移酵素SMYD3の同定と機能解析2012

    • Author(s)
      陳 明、甘 翔、DENG Lin、勝二 郁夫、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Identification and characterization of a novel NS5A-interacting protein, SMYD3.2012

    • Author(s)
      Chen M, Gan X, Deng L, Shoji I, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C 型肝炎ウイルス感染はHNF-1 αの発現を負に制御しGLUT2 遺伝子発現を抑制する2012

    • Author(s)
      勝二 郁夫, 松井 千絵子, 兼田 祟作, Imelda Rosalyn Sianipar, Deng Lin, 堀田 博
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C 型肝炎ウイルスによるGLUT2 遺伝子発現抑制の分子機構2012

    • Author(s)
      松井千絵子、勝二郁夫、Deng Lin、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルス感染による転写因子FoxO1脱リン酸化の分子機序の解析2012

    • Author(s)
      DENG Lin、金子 昌裕、河本 真理、姜 大鵬、勝二 郁夫、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C 型肝炎ウイルス NS5A 蛋白質の新規結合因子ヒストンメチル基転移酵素SMYD3 の同定と機能解析2012

    • Author(s)
      陳明、甘翔、Deng Lin、勝二郁夫、堀田博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCV infection induces lysosomal degradation of hepatocyte nuclear factor 1α via interaction with HCV NS5A protein2012

    • Author(s)
      Matsui C, Shoji I, Deng L, Hotta H
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスに対する予防および治療ワクチン開発に関する研究2012

    • Author(s)
      姜 大鵬、Ratnoglik Lulut Suratno1、青木 千恵、Deng Lin、勝二 郁夫、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Identification and characterization of a novel NS5A-interacting protein2012

    • Author(s)
      Chen M, Gan X, Deng L, Shoji I, Hotta H
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスによるGLUT2遺伝子発現抑制の分子機構2012

    • Author(s)
      松井 千絵子、勝二 郁夫、DENG Lin、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Molecular mechanism of hepatitis C virus-induced glucose metabolism disorder.2012

    • Author(s)
      Shoji I
    • Organizer
      The 10th JSH single topic conference
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCV infection induces lysosomal degradation of hepatocyte nuclear factor 1α via interaction with HCV NS5A protein.2012

    • Author(s)
      Matsui C, Shoji I, Deng L, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C 型肝炎ウイルス NS5A の新規結合タンパク質であるヒストンメチル基転移酵素SMYD3 の同定2011

    • Author(s)
      甘翔、Lin Deng、陳明、井出良浩、勝二郁夫、堀田博
    • Organizer
      第64回日本細菌学会関西支部総会
    • Place of Presentation
      大阪
    • Year and Date
      2011-11-19
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, Chieko M, Jang DP, Deng L, Ide Y-H, andHotta H
    • Organizer
      第34回日本分子生物学会年
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスのインターフェロン・リバビリン治療応答性を規定するウイルス側因子2011

    • Author(s)
      勝二郁夫、Ahmed El-Shamy, 堀田博
    • Organizer
      第2回神戸肝炎ウイルス学術講演会
    • Place of Presentation
      ホテルオークラ神戸(神戸市)(招待講演)
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, El-Shamy A, Deng L, Jang DP, Ide Y-H, Hotta H
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスのインターフェロン・リバビリン治療応答性を規定するウイルス側因子2011

    • Author(s)
      勝二郁夫、Ahmed El-Shamy, 堀田博
    • Organizer
      第2回神戸肝炎ウイルス学術講演会
    • Place of Presentation
      神戸
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, Chieko M, Jang DP, Deng L, Ide Y-H, Hotta H
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that targets hepatitis C virus NS5A protein for ubiquitylation.2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, MakimotoM, El-Shamy A, Deng L, Jang DP, IdeY-H, and Hotta H
    • Organizer
      18thInternational symposium on hepatitis C virus and related viruses
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスNS5Aの新規結合タンパク質であるヒストンメチル基転移酵素SMYD3の同定2011

    • Author(s)
      甘翔、Lin Deng、陳明、井出良浩、勝二郁夫、堀田博
    • Organizer
      第64回日本細菌学会関西支部総会
    • Place of Presentation
      大阪府立大学(堺市)
    • Year and Date
      2011-11-19
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that targets hepatitis C virus NS5A protein for ubiquitylation2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, El-Shamy A, Deng L, Jang DP, Ide Y-H, Hotta H
    • Organizer
      18^<th> International symposium on hepatitis C virus and related viruses
    • Place of Presentation
      シアトルシェラトンホテル(シアトル、米国)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, El-Shamy A, Deng L, Jang DP, Ide Y-H, and Hotta H
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] 糖代謝に及ぼすC型肝炎ウイルスの影響及びその分子機序の解析2010

    • Author(s)
      Deng L, 兼田崇作, 井出良浩, 勝二郁夫,堀田博
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルス感染は糖新生系を亢進し、糖尿病発症に関与する2010

    • Author(s)
      堀田博、井出良浩、勝二郁夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      ホテルメトロポリタン山形(山形県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCVによる糖代謝障害の分子機序2010

    • Author(s)
      勝二郁夫、Deng L、堀田博
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Molecular mechanism of HCV-induced suppression of glucose transporter (GLUT)2 expression.2010

    • Author(s)
      Shoji I, Kaneda S, Deng L, Ide Y-H, Hotta H.
    • Organizer
      17th International Meeting on hepatitis C virus and related viruses.
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスNS5Aに結合するユビキチンリガーゼの同定2010

    • Author(s)
      岡田典子、勝二郁夫、甘翔、Deng L、姜大鵬、井出良浩、堀田博
    • Organizer
      第33回日本分子生物学会年会(BMB2010)
    • Place of Presentation
      神戸国際展示場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCV-induced generation of reactive oxygen species leads to Bax-mediated apoptosis through activation of the c-Jun NH_2-terminal kinase signaling pathway.2010

    • Author(s)
      Deng L, Ide YH, Shoji I, Hotta H
    • Organizer
      17th International Meeting on hepatitis C virus and related viruses.
    • Place of Presentation
      Yokohama, Kanagawa.
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] 糖代謝に及ぼすC型肝炎ウイルスの影響及びその分子機序の解析2010

    • Author(s)
      Deng L, 兼田崇作、井出良浩、勝二郁夫、堀田博
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      あわぎんホール(徳島県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Role of the proteasome pathways in the hepatitis C virus life cycle2010

    • Author(s)
      Shoji I
    • Organizer
      RCC-ERI Seminar
    • Place of Presentation
      National Institute of Health, Bankok, Thailand.
    • Year and Date
      2010-08-08
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Molecular mechanism of HCVinduced suppression of glucose transporter(GLUT)2 expression.2010

    • Author(s)
      Shoji I, Kaneda S, Deng L, Ide Y-H,Hotta H.
    • Organizer
      17thInternational Meeting on hepatitis C virus and related viruses
    • Place of Presentation
      Yokohama, Kanagawa
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] E6AP uibiquitin ligase mediatesubiquitin-dependent degradation of peroxiredoxin 12010

    • Author(s)
      Shoji I, Nasu J, Murakami K, Miyagawa S, Yamashita R, IchimuraT, Wakita T, Ide Y-H, Hotta H, Miyamura T, Suzuki T,Satoh T
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCVによる糖代謝障害の分子機序2010

    • Author(s)
      勝二郁夫、Deng L、堀田博
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      あわぎんホール(徳島県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] E6AP uibiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 1.2010

    • Author(s)
      Shoji I, Nasu J, Murakami K, Miyagawa S, Yamashita R, Ichimura T, Wakita T, Ide Y-H, Hotta H, Miyamura T, Suzuki T, Satoh T.
    • Organizer
      第33回日本分子生物学会年会(BMB2010)
    • Place of Presentation
      神戸国際展示場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルス感染は糖新生系を亢進し、糖尿病発症に関与する2010

    • Author(s)
      堀田博、井出良浩、勝二郁夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCV-induced generation of reactive oxygen species leads to Bax-mediated apoptosis through activation of the c-Jun NH_2-terminal kinase signaling pathway.2010

    • Author(s)
      Deng L, Ide Y-H, Shoji I, Hotta H.
    • Organizer
      17th International Meeting on hepatitis C virus and related viruses.
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Role of the proteasome pathways in the hepatitis Cvirus life cycle2010

    • Author(s)
      Shoji I
    • Organizer
      RCC-ERI Seminar
    • Place of Presentation
      National Institute of Health, Bankok,(Thailand)(招待講演)
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスNS5Aに結合するユビキチンリガーゼの同定2010

    • Author(s)
      岡田典子、勝二郁夫、甘翔、Deng L、姜大鵬、井出良浩、堀田博
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスによるミトコンドリア介在性アポトーシス誘導機構の解明.

    • Author(s)
      甘翔, DENG Lin, 陳明, 勝二郁夫, 堀田博
    • Organizer
      第62回日本ウイルス学会学術集会.
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV dysregulates Smad2/3- and Smad1/5-signaling pathways of the TGF-β superfamily.

    • Author(s)
      Matsuoka Y, Deng L, Asahi A, Aoki C, Shoji I, Hotta H
    • Organizer
      21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるTGF-βスーパーファミリーにおけるSmad2/3とSmad1/5/9経路の脱制御とその分子機序の解明.

    • Author(s)
      松岡陽子, DENG Lin, 朝日朱美, 青木千恵, 勝二郁夫, 堀田博
    • Organizer
      第62回日本ウイルス学会学術集会.
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] hysical and functional interaction between an OTU deubiquitinase and HCV NS5A protein.

    • Author(s)
      Sianipar I R, Shoji I, Matsui C, Minami N, Deng L, Hotta H
    • Organizer
      The 21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A interacts with lysine methyltransferase SMYD3 and transcriptionally activates the protein disulfide isomerase gene AGR3.

    • Author(s)
      Chen M, Gan X, Deng L, Shoji I, Hotta H
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV induces Bim/Bax-mediated apoptosis through the ROS/JNK signaling pathway.

    • Author(s)
      Deng L, Chen M, Shoji I, Hotta H
    • Organizer
      The 21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Determinants of specific interaction between hepatitis C virus NS5A and HNF-1α protein.

    • Author(s)
      Matsui C, Shoji I, Sianipar I R, Minami N, Deng L, Hotta H
    • Organizer
      The 21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A protein physically and functionally interacts with an OTU deubiquitinase.

    • Author(s)
      Sianipar IR, Shoji I, Matsui C, Minami N, Deng L, Hotta H
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるHepatocyte nuclear factor (HNF) -1α蛋白質の選択的分解機構

    • Author(s)
      松井千絵子, 勝二郁夫, Sianipar I R, 南 奈苗, DENG Lin, 堀田博
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルスによるHNF-1α蛋白質の選択的分解機構の解析.

    • Author(s)
      勝二郁夫, 松井千絵子, Imelda Rosalyn Sianipar, 南奈苗, Lin Deng, 堀田博
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24590976
  • 1.  HOTTA Hak (40116249)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 38 results
  • 2.  IDE Yoshihiro (70258606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 28 results
  • 3.  DENG Lin (40437497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 38 results
  • 4.  SAKURAI Tetsu (30222003)
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    # of Collaborated Products: 0 results
  • 5.  足達 哲也 (60345014)
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  • 6.  定 清直 (10273765)
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  • 7.  長野 基子 (90304089)
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  • 8.  太田 和宏 (00273748)
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  • 9.  杉下 智彦 (00795015)
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  • 10.  大月 一弘 (10185324)
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  • 11.  辛島 理人 (20633704)
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  • 12.  工藤 晴子 (20910037)
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  • 13.  中澤 港 (40251227)
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  • 14.  新川 匠郎 (60802486)
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  • 15.  青山 薫 (70536581)
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  • 16.  梅屋 潔 (80405894)
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  • 17.  小川 啓一 (90379496)
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  • 18.  齋藤 剛 (90508912)
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  • 19.  益田 岳 (00455916)
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  • 20.  クラクストン ジェームズ (90792341)
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  • 21.  松浦 善治
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  • 22.  福永 浩司
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  • 23.  脇田 隆字
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  斉藤 あつ子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  斎藤 貴史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  アリ フセインハッサン
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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