SEKINE Chiyoko 関根知世子

… Alternative Names

関根知世子セキネチヨコ

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Researcher Number	40392005
Other IDs
Affiliation (based on the past Project Information) *help	2016: 帝京大学, 医学部, 助教 2015: 帝京大学, 医学部, 講師 2014: 帝京大学, 医学部, 助教 2012: 順天堂大学, 医学(系)研究科(研究院), 助教 2010 – 2012: 順天堂大学, 医学部, 助教 2006: 順天堂大学, 医学部, 助手 2005: 独立行政法人理化学研究所, 自己免疫病戦略研究ユニット, 研究員
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology Except Principal Investigator Cardiovascular medicine / Collagenous pathology/Allergology
Keywords	Principal Investigator 関節リウマチ / Notch / 炎症性メディエーター / 破骨細胞 / リンパ管 / 血管新生 / 破骨細胞分化 / 炎症 / 関節炎 / 滑膜増殖抑制 / サイクリン依存性キナーゼ阻害薬 / サイクリン依存性キナーゼ阻害因子 … More Except Principal Investigator … More 自然炎症 / TLR / ATF3 / HDL / 動脈硬化 / NLRP3 / IL-1 / リウマチ学 / インフラマソーム Less

Innate immunity in the pathogenesis of rheumatoid arthritis
- Principal Investigator
  
  Hajime Kono
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Teikyo University
Ｎｏｔｃｈリガンド分子阻害による関節炎抑制機序の解明Principal Investigator
- Principal Investigator
  
  関根知世子
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Teikyo University
The anti-inflammatory mechanism of HDL in atherosclerosis
- Principal Investigator
  
  KONO Hajime
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Teikyo University
The role of Notch on rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  SEKINE Chiyoko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
関節リウマチの病態におけるサイクリン依存性キナーゼ阻害因子の機能と役割Principal Investigator
- Principal Investigator
  
  関根知世子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
  The Institute of Physical and Chemical Research

All 2015 2014 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Macrophage-derived delta-like protein 1 enhances interleukin-6 and matrix metalloproteinase 3 production by fibroblast-like synoviocytes in mice with collagen-induced arthritis.2014
- Author(s)
  Sekine C, Nanki T, Yagita H
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 66 Issue: 10 Pages: 2751-61
- DOI
  10.1002/art.38743
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461475
[Journal Article] Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid - lysophosphatidic acid receptor 1 cascade.2014
- Author(s)
  Miyabe Y, Miyabe C, Iwai Y, Yokoyama W, Sekine C, Sugimoto K, Harigai M, Miyasaka M, Miyasaka N, Nanki T.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 16 Issue: 5 Pages: 461-461
- DOI
  10.1186/s13075-014-0461-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-26461475
[Journal Article] 関節リウマチとIL-72014
- Author(s)
  関根　知世子、河野　肇
- Journal Title
  
  リウマチ科
  
  Volume: 51 Pages: 438-443
- Data Source
  KAKENHI-PROJECT-26461475
[Journal Article] Expression of Notch receptors and ligands on immature and mature T cells2012
- Author(s)
  Koyanagi A, Sekine C, Yagita H
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: Vol.418 Issue: 4 Pages: 799-805
- DOI
  10.1016/j.bbrc.2012.01.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591085
[Journal Article] Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes2012
- Author(s)
  Sekine C, Koyanagi A, Koyama N, Hozumi K, Chiba S, Yagita H
- Journal Title
  
  Arthritis Research and Ttherapy
  
  Volume: Vol.14 Issue: 2
- DOI
  10.1186/ar3758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591085, KAKENHI-PROJECT-23659482
[Journal Article] Small-molecule inhibitors of cyclin-dependent kinases as a new class of antirheumatic drugs
- Author(s)
  関根知世子
- Journal Title
  
  Proceedings of the National Academy of Sciences (発表予定)
- Data Source
  KAKENHI-PROJECT-17790685
[Presentation] Delta-like 1 enhances the production of pro-inflammatory mediators by fibroblast-like synoviocytes2015
- Author(s)
  Sekine C
- Organizer
  2015 American College of Rheumatology (ACR)/ARHP Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461475
[Presentation] Blockade of Delta-like1 suppresses osteoclastogenesis and arthritis2011
- Author(s)
  関根知世子
- Organizer
  日本免疫学会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-22591085
[Presentation] Blockade of Delta-like1 suppresses osteoclastogenesis and arthritis2011
- Author(s)
  関根知世子
- Organizer
  アメリカリウマチ学会(ACR)
- Place of Presentation
  マコーミックプレイスコンベンションセンター(シカゴ)
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-22591085
[Presentation] Blockade of Delta-like 1 suppresses osteoclastogenesis and arthritis2010
- Author(s)
  関根知世子
- Organizer
  7^<th> International Conference on Autoimmunity
- Place of Presentation
  GR Ljubljana Exhibition and Convention Centre(スロベニア)
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-22591085
[Presentation] Delta-like 1 enhances the production of pro-inflammatory mediators by fibroblast-like synoviocytes
- Author(s)
  関根　知世子
- Organizer
  第３回　Controversies in Rheumatology & Autoimmunity 国際学会　（CORA 2015）
- Place of Presentation
  ソレント（イタリア）
- Year and Date
  2015-03-12 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26461475
[Presentation] Notch signaling is not essential for the development of marginal zone B cells in autoimmune mice
- Author(s)
  関根　知世子
- Organizer
  8th International Congress on Autoimmunity
- Place of Presentation
  グラナダ展示会議場　（スペイン）
- Data Source
  KAKENHI-PROJECT-22591085

1. Hajime Kono (60585074)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. NANKI Toshihiro (00282749)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. SEKI Reiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YANAGIDA Tamiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 宮坂昌之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SEKINE Chiyoko 関根 知世子

関根 知世子 セキネ チヨコ

Research Projects

Research Products

Co-Researchers

Innate immunity in the pathogenesis of rheumatoid arthritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ｎｏｔｃｈリガンド分子阻害による関節炎抑制機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The anti-inflammatory mechanism of HDL in atherosclerosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Notch on rheumatoid arthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

関節リウマチの病態におけるサイクリン依存性キナーゼ阻害因子の機能と役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Macrophage-derived delta-like protein 1 enhances interleukin-6 and matrix metalloproteinase 3 production by fibroblast-like synoviocytes in mice with collagen-induced arthritis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid - lysophosphatidic acid receptor 1 cascade.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 関節リウマチとIL-72014

Author(s)

Journal Title

Data Source

[Journal Article] Expression of Notch receptors and ligands on immature and mature T cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Small-molecule inhibitors of cyclin-dependent kinases as a new class of antirheumatic drugs

Author(s)

Journal Title

Data Source

[Presentation] Delta-like 1 enhances the production of pro-inflammatory mediators by fibroblast-like synoviocytes2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Blockade of Delta-like1 suppresses osteoclastogenesis and arthritis2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Blockade of Delta-like1 suppresses osteoclastogenesis and arthritis2011

Author(s)

Organizer

Place of Presentation

Year and Date

SEKINE Chiyoko 関根知世子

関根知世子セキネチヨコ