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Ando Takayuki  安藤 隆幸

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ANDO Takayuki  安藤 隆幸

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Researcher Number 40402226
Other IDs
Affiliation (Current) 2025: 静岡県環境衛生科学研究所, 医薬食品部, 創薬プロジェクトリーダー・主幹
Affiliation (based on the past Project Information) *help 2025: 静岡県環境衛生科学研究所, 医薬食品部, 創薬プロジェクトリーダー・主幹
2022 – 2024: 静岡県環境衛生科学研究所, 医薬食品部, 創薬プロジェクトリーダー・主査
2017 – 2022: 静岡県環境衛生科学研究所, 医薬食品部, 主査
2014: 静岡県環境衛生科学研究所
2013 – 2014: 静岡県環境衛生科学研究所, その他部局等, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 38040:Bioorganic chemistry-related / Tumor therapeutics
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 63020:Radiation influence-related / Basic Section 50010:Tumor biology-related / Clinical oncology
Keywords
Principal Investigator
構造活性相関 / 阻害剤 / RNA修飾酵素 / 抗がん剤 / 類縁体合成 / 低分子化合物 / 増殖抑制 / 脳腫瘍 / グリオーマ / 悪性脳腫瘍 … More
Except Principal Investigator
… More DNA修復経路 / RAD52 / 抗がん剤 / 低分子化合物 / がん治療 / 免疫チェックポイント阻害剤 / ASMS / 一本鎖アニーリング / 遺伝的不安定性 / DNA修復タンパク / 薬剤耐性 / 遺伝性疾患 / DNA損傷応答 / ゲノム不安定性 / 標的治療 / 経口投与 / 極低用量 / スクリーニング系 / 担がんマウス / BRCA変異がん / マウス実験 / 感受性 / 化合物合成 / SSA / 標的阻害 / 発がん / DNA損傷 / RECQL4 / DNA修復 / がん幹細胞特異的翻訳 / 低分子化合物開発 / タンパク質合成 / がん幹細胞 / 患者層別化検証 / 阻害剤開発 / 膠芽腫幹細胞 / 翻訳制御機構 / 腫瘍幹細胞 / 膠芽腫 / エピトランスクリプトーム創薬 / 肺がん / 転写因子 / アクチン / 細胞骨格 / 創薬 / スフィンゴ脂質 / 細胞遊走 / セラミド / 転移 / CERS6 / 肺癌 / 免疫チェックポイント / PD-1/PD-L inhibitor / PD-1/PD-L1 inhibitor / PD-1/PD-L1 / PD-L1 / 国際情報交換 / がん幹細胞治療薬 Less
  • Research Projects

    (9 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (19 People)
  •  Applied research of novel PD-1/PD-L1 small molecule inhibitors for the development of drugs

    • Principal Investigator
      菊地 康文
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Shizuoka Cancer Center Research Institute
  •  Elucidation of regulatory mechanisms for cancer therapy resistance using DNA repair properties

    • Principal Investigator
      香崎 正宙
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 63020:Radiation influence-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  新規抗がん剤開発を目指すtRNA修飾酵素と阻害化合物の構造活性相関解明Principal Investigator

    • Principal Investigator
      安藤 隆幸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38040:Bioorganic chemistry-related
    • Research Institution
      Shizuoka Institute of Environment and Hygiene
  •  Development of epitranscriptome anticancer drugs targeting glioblastoma stem cells

    • Principal Investigator
      Fujimura Atsushi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Okayama University
  •  Innovative drug development targeting specific DNA repair pathway in cancer cells

    • Principal Investigator
      Kohzaki Masaoki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 63020:Radiation influence-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Identification of small molecular compounds with PD-1 / PD-L1 inhibitory activity by in silico

    • Principal Investigator
      Ashizawa Tadashi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Shizuoka Cancer Center Research Institute
  •  Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells

    • Principal Investigator
      Suzuki Motoshi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Fujita Health University
  •  Study of novel salicylic acid analogs for anti brain tumor reagentPrincipal Investigator

    • Principal Investigator
      Ando Takayuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Shizuoka Institute of Environment and Hygiene
  •  Development of a novel small-molecule compounds targeting cancer stem cells derived from malignant glioma

    • Principal Investigator
      ASHIZAWA Tadashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical oncology
    • Research Institution
      Shizuoka Cancer Center Research Institute

All 2021 2020 2019 2018

All Journal Article Presentation Patent

  • [Journal Article] Antitumor activity of the PD-1/PD-L1 binding inhibitor BMS-202 in the humanized MHC-double knockout NOG mouse2019

    • Author(s)
      Ashizawa T, Iizuka A, Tanaka E, Kondou R, Miyata H, Maeda C, Sugino T, Yamaguchi K, Ando T, Ishikawa Y, Ito M, Akiyama Y.
    • Journal Title

      Biomed. Res.

      Volume: 40 Issue: 6 Pages: 243-250

    • DOI

      10.2220/biomedres.40.243

    • NAID

      130007761178

    • ISSN
      0388-6107, 1880-313X
    • Year and Date
      2019-12-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07315, KAKENHI-PROJECT-17K07209
  • [Journal Article] Identification of benzo[d]pyrrolo[2,1-b]thiazole derivatives as CENP-E inhibitors.2019

    • Author(s)
      Yamane M, Sawada JI, Ogo N, Ohba M, Ando T, Asai A.Yamane M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 519 Issue: 3 Pages: 505-511

    • DOI

      10.1016/j.bbrc.2019.09.028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07315, KAKENHI-PROJECT-18H02559
  • [Patent] スラミンを含む組成物2021

    • Inventor(s)
      香﨑正宙 ・ 安藤隆幸
    • Industrial Property Rights Holder
      産業医大 ・ ファルマバレー
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-044471
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K12172
  • [Patent] スラミンを含む組成物2021

    • Inventor(s)
      香崎正宙・安藤隆幸
    • Industrial Property Rights Holder
      香崎正宙・安藤隆幸
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-044471
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K12172
  • [Patent] PD-1及び/又はPD-L1の阻害剤2021

    • Inventor(s)
      秋山靖人、芦澤忠、飯塚明、井上謙吾、安藤隆幸、石川吉伸
    • Industrial Property Rights Holder
      静岡県、PVPSO、静岡県公立大学法人
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-045476
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-18K07315
  • [Patent] SSA阻害活性を有する化合物の試験方法2020

    • Inventor(s)
      香﨑正宙 ・ 安藤隆幸
    • Industrial Property Rights Holder
      産業医大 ・ ファルマバレー
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-031591
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K12172
  • [Patent] がん転移抑制剤2019

    • Inventor(s)
      鈴木元、竹内俊幸、高橋隆、磯村久徳、小泉惠子、安藤隆幸
    • Industrial Property Rights Holder
      学校法人藤田学園
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-18H02698
  • [Presentation] ヒト化MHCダブルノックアウトNOGマウスを用いたPD-1/PD-L1結合阻害剤BMS-202の抗腫瘍効果2019

    • Author(s)
      芦澤 忠、飯塚 明、丸山 宏二、安藤 隆幸、山口 建、秋山 靖人
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07315
  • [Presentation] Foxp3阻害化合物の探索及び作用機序解析2018

    • Author(s)
      園田 祐大、小郷 尚久、安藤 隆幸、村岡 大輔、浅井 章良
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07315
  • 1.  石川 吉伸 (00305004)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  ASHIZAWA Tadashi (10443441)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  AKIYAMA Yasuto (70222552)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Fujimura Atsushi (10771082)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Kohzaki Masaoki (90717977)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Suzuki Motoshi (80236017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  小郷 尚久 (20501307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  水谷 泰嘉 (10546229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  竹内 俊幸 (20538483)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  新美 敦子 (50508984)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  村手 隆 (30239537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  黒住 和彦 (20509608)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  富澤 一仁 (40274287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  増本 年男 (40715083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  中村 仁 (50828407)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  魏 范研 (90555773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  工藤 晃大 (40911433)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  香川 亘 (70415123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  菊地 康文 (90968661)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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