KOBAYASHI Takeshi 小林剛

Researcher Number	40402565
Other IDs	https://orcid.org/0000-0002-4372-5285
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2015 – 2023: 名古屋大学, 医学系研究科, 講師 2015 – 2016: 名古屋大学, 医学(系)研究科(研究院), 講師 2014: 名古屋大学, 大学院医学研究科, 助教 2011 – 2014: 名古屋大学, 医学(系)研究科(研究院), 助教 2012: 名古屋大学, 医学研究科, 助教 … More 2010: Nagoya University, 医学系研究科, 助教 2010: 名古屋大学, 大学院・医学系研究科, 助教 2007 – 2009: Nagoya University, GRADUATE SCHOOL OF MEDCINE, RESEARCHER 2007: Nagoya University, 大学院・医学研究科, 研究員 2006: 名古屋大学, 大学院医学系研究科, 研究員 Less
Review Section/Research Field	Principal Investigator Biophysics / Basic Section 44010:Cell biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / 宇宙生命学 / Mechanobiology Except Principal Investigator Complex systems / Basic Section 59010:Rehabilitation science-related / Basic Section 59040:Nutrition science and health science-related / Biophysics / Orthopaedic surgery
Keywords	Principal Investigator 小胞体 / ミトコンドリア / 可視化解析 / ダイナミクス / オルガネラ接触領域 / メカノセンサー / 感知 / メカニカルストレス / 細胞骨格 / 機械刺激 … More / カルシウム / メカノバイオロジー / CHANNEL / RECEPTOR / PLASMA MEMBRANE / チャンネル / 受容体 / 生体膜 / 細胞力覚 / 動物細胞 / 微小重力 / 宇宙生命科学 / 1分子計測 / １分子計測 / 生物物理 / シグナル伝達 / 機械刺激感知 / イメージング / 細胞内輸送 / P2X4 / 血流 … More Except Principal Investigator メカノセンシング / 機械刺激受容チャネル / 酸化ストレス / ミトコンドリア / 筋萎縮 / 培養筋管 / リハビリテーション / 筋管細胞 / コスタメア / 筋 / 超音波 / メカニカルストレス / 廃用性筋萎縮 / メタボリックシンドローム / UCP3 / Mitofusin2 / Calcium inflax / ROS signaling / NAC / 尾部懸垂 / mitofusin2 / ROSシグナル / ニュートリションシグナル / メカノシグナル / 抗酸化栄養素 / アコニターゼ / MAM / ロコモティブシンドローム / 動物細胞 / 力学的ストレス / 細胞内シグナル伝達 / 過重力 / 微小重力 / iPS細胞 / 模擬微小重力 / 遠心顕微鏡 / 機械刺激 / 血管内皮細胞 / PKC / YAP / 回転蛍光顕微鏡 / 圧力 / 重力 / メカノバイオロジー / 宇宙医学 / 宇宙生物学 / 宇宙 / 接着斑 / 細胞骨格 / 機械受容チャネル / 足場 / 次世代シークエンサー / 無重力 / メカノセンサー / ユビキチンリガーゼ / 生物規範 / 生物模倣 / 生物規範工学 / 機械工学 / 生物学 / 工学 / 生物規範飛行マクロメカニクス・システム: / バイオミメティクス・デザイン / 生物規範飛行マクロメカニクス・システム / 生物規範細胞ミクロメカニクス・システム / 生物マルチスケール・メカニクス・システム / 細胞 / 昆虫 / サブセルラーサイズ / 生物規範細胞 / 生物規範飛行 / バイオミメティクス / バイオメカニクス / バイオミメティクデザイン / 生物マルチスケールメカニクス / 生物飛行マクロメカニクス / 細胞ミクロメカニクス Less

Imaging analysis of ER-mitochondria contact sites in living cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Nagoya University
Analysis of mechanosensing/transduction in costamere by ultrasound
- Principal Investigator
  
  清島大資
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Tokai University
Mechano-nutrition-signaling for disuse muscle atrophy
- Principal Investigator
  
  NIKAWA Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokushima
Imaging analysis of mechno-sensing in mitochondria of living cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Nagoya University
Mechanosensing Mechanisms for Sensing Mechanical Stress Including Gravitational Changes
- Principal Investigator
  
  Naruse Keiji
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Okayama University
Initial step of gravity sensing in cultured animal cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  宇宙生命学
- Research Institution
  Nagoya University
Bio-inspired Mechanical Systems
- Principal Investigator
  
  Liu Hao
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Chiba University
Mitochondria is a key signal inducer for unloading stress toward muscle atrophy
- Principal Investigator
  
  NIKAWA Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokushima
Possible roles of actomyosin and mechanosensitive channels in substrate rigidity sensing of cells
- Principal Investigator
  
  SOKABE Masahiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
Dynamics of myristoylated amino-terminal domain of Src in the plasma membrane of mechano-stimulated cells studied by single molecule imagingPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mechanobiology
- Research Institution
  Nagoya University
IMAGING ANALYSIS OF CELL SURFACE P2X4 RECEPTOR UP-REGULATED BY FLOW SHEAR STRESSPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
ANALYSES OF MOLECULAR MECHANISM OF STRETCH-ACTIVATED CHANNELS USING SINGIPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takeshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University

[Book] “再生医工学におけるメカノバイオロジーII:創傷治癒/基質高度検知/基質工学” 曽我部正博編集『メカノバイオロジー：細胞が力を感じ応答する仕組み』(第22章)2015
- Author(s)
  木戸秋悟、小林剛
- Total Pages
  368
- Publisher
  化学同人
- Data Source
  KAKENHI-PLANNED-24120007
[Book] 再生工学におけるメカノバイオロジーII2014
- Author(s)
  木戸秋悟、小林剛
- Publisher
  化学同人 (印刷中)
- Data Source
  KAKENHI-PROJECT-23612002
[Book] Recent Advances in Mechanobiology2012
- Author(s)
  Sokabe M, Sawada Y, Nomura K, Yoshimura K, Kobayashi T.
- Total Pages
  200
- Publisher
  Shanghai Sci Tech Liter Pub House
- Data Source
  KAKENHI-PROJECT-24247028
[Book] ベーシックマスター細胞生物学(「細胞膜」神谷律、尾張部克志編集第5章)2009
- Author(s)
  小林剛
- Publisher
  オーム社
- Data Source
  KAKENHI-PROJECT-20570152
[Book] 組織細胞化学2008(全反射蛍光顕微鏡(TIRFM)を用いたイメージング)2008
- Author(s)
  小林剛
- Publisher
  日本組織細胞化学会
- Data Source
  KAKENHI-PROJECT-20570152
[Book] 高田邦昭、斎藤尚亮、川上速人編集「染色・バイオイメージング実験ハンドブック」2006
- Author(s)
  小林剛
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Journal Article] モデル生物の筋萎縮とミトコンドリアCa2+2023
- Author(s)
  寺西美佳、東谷篤志、小林　剛
- Journal Title
  
  Precision Medicine
  
  Volume: 6 Pages: 659-662
- Data Source
  KAKENHI-PROJECT-21K06149
[Journal Article] Increased mitochondrial Ca2+ contributes to health decline with age and Duchene muscular dystrophy in C. elegans.2023
- Author(s)
  Higashitani A, Teranishi M, Nakagawa Y, Itoh Y, Sudevan S, Szewczyk NJ, Kubota Y, Abe T, Kobayashi T
- Journal Title
  
  FASEB J
  
  Volume: 37 Issue: 4
- DOI
  10.1096/fj.202201489rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06149
[Journal Article] ミトコンドリアにおける機械刺激受容2023
- Author(s)
  小林　剛、田中瑞奈、寺西美佳、東谷篤志
- Journal Title
  
  細胞
  
  Volume: 55 Pages: 55-58
- Data Source
  KAKENHI-PROJECT-21K06149
[Journal Article] Meclozine ameliorates skeletal muscle pathology and increases muscle forces in mdx mice2022
- Author(s)
  Kawamura Yusuke、Hida Tetsuro、Ohkawara Bisei、Matsushita Masaki、Kobayashi Takeshi、Ishizuka Shinya、Hiraiwa Hideki、Tanaka Satoshi、Tsushima Mikito、Nakashima Hiroaki、Ito Kenyu、Imagama Shiro、Ito Mikako、Masuda Akio、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 592 Pages: 87-92
- DOI
  10.1016/j.bbrc.2022.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21K06149, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K21309
[Journal Article] Sphingosine-1-Phosphate Induces ATP Release via Volume-Regulated Anion Channels in Breast Cell Lines2021
- Author(s)
  Furuya K, Hirata H, Kobayashi T, Sokabe M
- Journal Title
  
  Life
  
  Volume: 11 Issue: 8 Pages: 851-851
- DOI
  10.3390/life11080851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06851, KAKENHI-PROJECT-21K06149
[Journal Article] Gravity sensing in plant and animal cells.2021
- Author(s)
  Takahashi K, Takahashi H, Furuichi T, Toyota M, Furutani-Seiki M, Kobayashi T, Watanabe-Takano H, Shinohara M, Numaga-Tomita T, Sakaue-Sawano A, Miyawaki A, Naruse K.
- Journal Title
  
  NPJ Microgravity
  
  Volume: 7 Issue: 1 Pages: 2-2
- DOI
  10.1038/s41526-020-00130-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-20K08956, KAKENHI-PROJECT-20K21896, KAKENHI-PLANNED-18H05491, KAKENHI-PROJECT-19H03140, KAKENHI-PROJECT-18K09050, KAKENHI-PROJECT-18K19291, KAKENHI-PROJECT-19H03991
[Journal Article] Morin attenuates dexamethasone-mediated oxidative stress and atrophy in mouse C2C12 skeletal myotubes2021
- Author(s)
  Ulla Anayt、Uchida Takayuki、Miki Yukari、Sugiura Kosuke、Higashitani Atsushi、Kobayashi Takeshi、Ohno Ayako、Nakao Reiko、Hirasaka Katsuya、Sakakibara Iori、Nikawa Takeshi
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 704 Pages: 108873-108873
- DOI
  10.1016/j.abb.2021.108873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10994, KAKENHI-PROJECT-19K11792, KAKENHI-PROJECT-19H04054, KAKENHI-PROJECT-21K06149, KAKENHI-PROJECT-19K18501, KAKENHI-PROJECT-20K19639
[Journal Article] ミトコンドリアに注目したメカノバイオロジー2021
- Author(s)
  小林　剛、田中瑞奈、寺西美佳、東谷篤志
- Journal Title
  
  Precision Medicine
  
  Volume: 4 Pages: 873-877
- Data Source
  KAKENHI-PROJECT-21K06149
[Journal Article] ミトコンドリアにおけるメカニカルストレス感知と応答2021
- Author(s)
  小林　剛、田中瑞奈、寺西美佳、東谷篤志
- Journal Title
  
  細胞
  
  Volume: 53 Pages: 62-65
- NAID
  40022742567
- Data Source
  KAKENHI-PROJECT-21K06149
[Journal Article] Morin attenuates dexamethasone-mediated oxidative stress and atrophy in mouse C2C12 skeletal myotubes2021
- Author(s)
  Anayt Ulla, Takayuki Uchida, Yukari Miki, Kosuke Sugiura, Atsushi Higashitani, Takeshi Kobayashi, Ayako Ohno, Reiko Nakao, Katsuya Hirasaka, Iori Sakakibara, Takeshi Nikawa
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 704
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04054
[Journal Article] モデル生物を用いた筋の老化とミトコンドリア2020
- Author(s)
  寺西美佳、小林　剛
- Journal Title
  
  細胞
  
  Volume: 52 Pages: 4-7
- Data Source
  KAKENHI-PROJECT-18K19291
[Journal Article] Ultra-high-purity Iron Is a Novel and Very Compatible Biomaterial2020
- Author(s)
  Khan L, Sato K, Okuyama S, Kobayashi T, Ohashi K, Hirasaka K, Nikawa T, Takada K, Higashitani A, Abiko K
- Journal Title
  
  J Mech Behav Biomed Mater
  
  Volume: 106 Pages: 103744-103744
- DOI
  10.1016/j.jmbbm.2020.103744
- NAID
  120007185170
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19291, KAKENHI-PROJECT-19K11792, KAKENHI-PROJECT-20H03248
[Journal Article] ミトコンドリアはメカノセンサーか？－新規メカニカルストレス感知機構の解析2020
- Author(s)
  小林　剛、田中瑞奈、寺西美佳、東谷篤志
- Journal Title
  
  細胞
  
  Volume: 52 Pages: 51-54
- Data Source
  KAKENHI-PROJECT-18K19291
[Journal Article] Reactive oxygen species up-regulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells.2018
- Author(s)
  Yuushi Okumura et al.
- Journal Title
  
  Am J Physiol Cell Physiol.
  
  Volume: 印刷中 Issue: 6 Pages: C721-C731
- DOI
  10.1152/ajpcell.00184.2017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09585, KAKENHI-PLANNED-15H05937, KAKENHI-PROJECT-15H04931, KAKENHI-PROJECT-15J40096, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-18K08453, KAKENHI-PLANNED-15H05936, KAKENHI-PUBLICLY-18H04981, KAKENHI-ORGANIZER-15H05935
[Journal Article] Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells2016
- Author(s)
  Maeda K, Enomoto A, Hara A, Asai N, Kobayashi T, Horinouchi A, Maruyama S, Ishikawa Y, Nishiyama T, Kiyoi H, Kato T, Ando K, Weng L, Mii S, Asai M, Mizutani Y, Watanabe O, Hirooka Y, Goto H, Takahashi M
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 22288-22288
- DOI
  10.1038/srep22288
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26506009, KAKENHI-PROJECT-15K21061, KAKENHI-PLANNED-24120007, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-25460493, KAKENHI-PROJECT-26670188, KAKENHI-PROJECT-25860293
[Journal Article] Ion channels activated by mechanical forces in bacterial and eukaryotic cells2015
- Author(s)
  Sokabe M, Sawada M, Kobayashi T
- Journal Title
  
  Subcell Biochem
  
  Volume: 72 Pages: 613-626
- DOI
  10.1007/978-94-017-9918-8_28
- ISBN
  9789401799171, 9789401799188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26506009, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-ORGANIZER-15H05935, KAKENHI-PLANNED-15H05936, KAKENHI-PLANNED-24120007, KAKENHI-PROJECT-24247028
[Journal Article] 骨と筋におけるメカノセンシングとメカノシグナリング2015
- Author(s)
  小林　剛、曽我部正博
- Journal Title
  
  THE BONE
  
  Volume: 29 Pages: 255-263
- Data Source
  KAKENHI-PROJECT-26506009
[Journal Article] 骨と筋におけるメカノセンシングとメカノシグナリング2015
- Author(s)
  小林剛、曽我部正博
- Journal Title
  
  THE BONE
  
  Volume: 29 Pages: 255-263
- Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24120007
[Journal Article] 骨と筋におけるメカノセンシングとメカノシグナリング2015
- Author(s)
  小林剛、曽我部正博
- Journal Title
  
  The BONE
  
  Volume: 29(35) Pages: 45-53
- Data Source
  KAKENHI-PLANNED-15H05936
[Journal Article] Proteoglycan from salmon nasal cartridge promotes in vitro wound healing of fibroblast monolayers via the CD44 receptor2015
- Author(s)
  G. Ito, T. Kobayashi, Y. Takeda, M. Sokabe
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 456 Issue: 3 Pages: 792-798
- DOI
  10.1016/j.bbrc.2014.12.037
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24120007, KAKENHI-PROJECT-26506009, KAKENHI-PROJECT-24247028
[Journal Article] 骨と筋におけるメカノセンシングとメカノシグナリング2015
- Author(s)
  小林剛、曽我部正博
- Journal Title
  
  The BONE
  
  Volume: 29 Pages: 45-53
- Data Source
  KAKENHI-PROJECT-24247028
[Journal Article] 機械受容チャネルのメカノトランスダクション機構2014
- Author(s)
  曽我部正博、澤田康之、小林　剛
- Journal Title
  
  細胞工学
  
  Volume: 33 Pages: 934-943
- Data Source
  KAKENHI-PROJECT-26506009
[Journal Article] 機械受容チャネルのメカノトランスダクション機構2014
- Author(s)
  曽我部正博、澤田康之、小林　剛
- Journal Title
  
  細胞工学
  
  Volume: 33 Pages: 934-943
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24120007
[Journal Article] Negative Charges in the Flexible N-Terminal Domain of Rho GDP-　Dissociation Inhibitors (RhoGDIs) Regulate the Targeting of the RhoGDI–　Rac1 Complex to Membranes2013
- Author(s)
  Ueyama T, Son J, Kobayashi T, Hamada T, Nakamura T, Sakaguchi H, Shirafuji T, Saito N
- Journal Title
  
  J. Immunol
  
  Volume: 191 Pages: 2560-2569
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24120007
[Journal Article] Negative Charges in the Flexible N-Terminal Domain of Rho GDP-Dissociation Inhibitors (RhoGDIs) Regulate the Targeting of the RhoGDI–Rac1 Complex to Membranes2013
- Author(s)
  Ueyama T, Son J, Kobayashi T, Hamada T, Nakamura T, Sakaguchi H, Shirafuji T, Saito N
- Journal Title
  
  J. Immunol
  
  Volume: 191 Pages: 2560-2569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23612002
[Journal Article] Negative Charges in the Flexible N-Terminal Domain of Rho GDP-Dissociation Inhibitors (RhoGDIs) Regulate the Targeting of the RhoGDI-Rac1 Complex to Membranes2013
- Author(s)
  Ueyama T, Son J, Kobayashi T, Hamada T, Nakamura T, Sakaguchi H, Shirafuji T, Saito N
- Journal Title
  
  J. Immunol.
  
  Volume: 191 Issue: 5 Pages: 2560-2569
- DOI
  10.4049/jimmunol.1300209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23612002, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during FcR-mediated phagocytosis --- Mechanism for acquisition of p40phox PI(3)P binding---2011
- Author(s)
  Ueyama T, Nakakita J, Nakamura T, Kobayashi T, Kobayashi T, Son J, Sakuma M, Sakaguchi H, Leto TL, Saito N
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Issue: 47 Pages: 40693-40705
- DOI
  10.1074/jbc.m111.237289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23612002
[Journal Article] Cooperation of p40^<phox>with p47^<phox>for Nox2 activation during FcγR-mediated phagocytosis -Mechanism for acquisition of p40^<phox>PI(3)P binding-2011
- Author(s)
  Ueyama T, Nakakita J, Nakamura T, Kobayashi T, Kobayashi T, Son J, Sakuma M, Sakaguchi H, Leto TL, Saito N
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 40693-40705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23612002
[Journal Article] Sensing substrate rigidity by mechanosensitive ion channels with stress fibers and focal adhesions2010
- Author(s)
  Kobayashi T, Sokabe M
- Journal Title
  
  Curr Opin Cell Biol
  
  Volume: 22 Pages: 669-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570152
[Journal Article] Sensing substrate rigidity by mechanosensitive ion channels with stress fibers and focal adhesions.2010
- Author(s)
  Kobayashi T, Sokabe M
- Journal Title
  
  Curr Opin Cell Biol. 22
  
  Pages: 669-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570152
[Journal Article] Stem cell factor/KIT signaling plays a pivotal role in regulating pigmentation in mammalian hair.2009
- Author(s)
  Hachiya A, Sriwiriyanont P, Kobayashi T, 他8名
- Journal Title
  
  J Pathol 218
  
  Pages: 30-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570152
[Journal Article] Stem cell factor/KIT signaling plays a pivotal role in regulating pigmentation in mammalian hair2009
- Author(s)
  Hachiya A, Sriwiriyanont P, Kobayashi T, Nagasawa A, Yoshida H, Ohuchi A, Kitahara T, Visscher MO, Takema Y, Tsuboi R, Boissy RE
- Journal Title
  
  J.Pathol. 218
  
  Pages: 30-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570152
[Journal Article] Regulation of clathrin dependent endocytosis by diacylglycerol kinase -importance of kinase activity and binding to AP2a2008
- Author(s)
  Kawasaki, T, Kobayashi, T, Takehiko, Ueyama, T, ShiraiY, SaitoN
- Journal Title
  
  Biochem.J 409
  
  Pages: 471-479
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Journal Article] Enzymological analysis of mutant protein kinase Cγ causing spinocerebellar ataxia type 14 and dysfunction in Ca^<2+> homeostasis.2008
- Author(s)
  Adachi N, Kobayashi T, Takahashi H, Kawasaki T, Shirai Y, Ueyama T, Matsuda T, Seki T, Sakai N, Saito N
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 19854-19863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570152
[Journal Article] Direct interaction of tyrosinase with Tyrpl to form heterodimeric complexes in vivo.2007
- Author(s)
  Takeshi Kobayashi
- Journal Title
  
  J. Cell Sci. 120
  
  Pages: 4261-4268
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570151
[Journal Article] Direct interaction of tyrosinase with Tyrpl to form heterodimeric complexes in vivo2007
- Author(s)
  Kobayashi, T, Hearing
- Journal Title
  
  J.Cell Sci 120
  
  Pages: 4261-4268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Journal Article] Total Internal Reflection Fluorescence Microscopic Observation2006
- Author(s)
  Kobayashi, F
- Journal Title
  
  SENSYOKU/BIOIMAGING-JLKKEN HANDBOOK 334
  
  Pages: 280-286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] 培養筋管に対する超音波照射の肥大経路の探索2023
- Author(s)
  清島大資, 縣信秀, 伊東佑太, 小林剛
- Organizer
  コ・メディカル形態機能学会第21回学術集会
- Data Source
  KAKENHI-PROJECT-21K11274
[Presentation] 国際宇宙ステーションにおけるライブセル共焦点イメージング2023
- Author(s)
  小林　剛、内田貴之、田中瑞奈、橋爪藤子、石毛智子、安西洋平、中山師生、梅村さや香、山﨑誠和、鈴木智美、笠原春夫、梅原真澄、谷川直樹、嶋津徹、伊藤剛、東端晃、二川健、曽我部正博
- Organizer
  日本宇宙生物科学会第37回大会
- Data Source
  KAKENHI-PROJECT-21K06149
[Presentation] Mechano-sensing of mitochondria in cultured animal cells2023
- Author(s)
  Kobayashi T, Tanaka M, Teranishi M, Nikawa T, Higashitani A
- Organizer
  International Symposium on Mechanobiology for Human Health: 8 years progress in the AMED-CREST/PRIME project on mechanobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06149
[Presentation] 培養筋管形成におけるα-アクチニンの役割の検討2022
- Author(s)
  清島大資, 平田宏聡 , 勝田紘基,　小林剛，縣信秀，伊東佑太, 木村菜穂子
- Organizer
  日本物理療法研究会学術大会
- Data Source
  KAKENHI-PROJECT-21K11274
[Presentation] 単一細胞における重力センシング機構の解明を目指して（Towards understanding the gravity sensing in single cells）2021
- Author(s)
  曽我部正博、小林　剛、二川　健、東端　晃
- Organizer
  日本機械学会　第33回バイオエンジニアリング講演会「宇宙とメカノバイオロジー」
- Invited
- Data Source
  KAKENHI-PROJECT-21K06149
[Presentation] Cell Gravisensing Project2021
- Author(s)
  Kobayashi T
- Organizer
  Joint CSA/ESA/JAXA/NASA ISS Increment 65 Science Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06149
[Presentation] Unloadingによる筋萎縮におけるCa2+-ROSシグナルの変化2020
- Author(s)
  藤岡大樹、内田貴之、杉浦宏祐、小林剛、東谷篤志、曽我部正博、二川健
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19H04054
[Presentation] Substrate rigidity sensing of mesenchymal stem cells by utilizing Trpv4 channels2020
- Author(s)
  Kobayashi T
- Organizer
  第43回日本分子生物学会年会　ワークショップAW-13「細胞基本機能を制御する細胞外硬度：感知の分子物理機構と応答シグナリング
- Invited
- Data Source
  KAKENHI-PROJECT-18K19291
[Presentation] 培養動物細胞におけるミトコンドリアの力学的刺激感知能の解析2019
- Author(s)
  田中瑞奈、寺西美佳、二川　健、曽我部正博、東谷篤志、小林　剛
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19291
[Presentation] 間葉系幹細胞の重力感知初期過程におけるPKCαの関与2019
- Author(s)
  堀池由朗、鬼頭舞帆、加藤信靖、田中瑞奈、橋爪藤子、東端晃、二川健、曽我部正博、小林　剛
- Organizer
  日本宇宙生物科学会第33回大会
- Data Source
  KAKENHI-PROJECT-18K19291
[Presentation] Dynamics of mitochondrial morphology and Ca2+ in C. elegans muscle cells with aging2019
- Author(s)
  Teranishi M, Kobayashi T, Ito Y, Sudevan S, Xintong W, Nagasawa R, Momma K, Higashitani A
- Organizer
  第42回日本分子生物学会年会　ワークショップ3AW-04 「ミトコンドリアの形と機能の新規連関」
- Invited
- Data Source
  KAKENHI-PROJECT-18K19291
[Presentation] 線虫体壁筋筋細胞および培養細胞におけるミトコンドリアの力学的刺激感知能の解析2019
- Author(s)
  小林　剛、伊藤侑晃、田中瑞奈、寺西美佳、清島大資、二川　健、曽我部正博、東谷篤志
- Organizer
  第5回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19291
[Presentation] ストレス線維の張力低下により誘導された接着斑解体におけるエンドサイトーシスの役割2018
- Author(s)
  堀池由朗,　田中瑞奈,　加藤信靖,　成瀬恵治,　曽我部正博,　小林　剛
- Organizer
  日本宇宙生物科学会第32回大会
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Toward the Elucidation of Cell Gravi-Sensing in Space2018
- Author(s)
  Sokabe M, Kobayashi T, Nikawa T, Naruse K, Higashibata A
- Organizer
  15th Korea-Japan Joint Seminar on Space Environment Utilization Research
- Invited
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Active Mechanosensing at Cell-Substrate and Cell-Cell Adhesions2018
- Author(s)
  Sokabe M, Kobayashi T, Hirata H
- Organizer
  Asian Biophysics Association Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] 線虫を用いた筋ミトコンドリア研究2018
- Author(s)
  東谷篤志, 小林剛
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] 線虫を用いた筋ミトコンドリア研究2018
- Author(s)
  東谷篤志、小林　剛
- Organizer
  第41回日本分子生物学会年会　ワークショップ3PW-09 「筋ミトコンドリア研究の新展開」
- Invited
- Data Source
  KAKENHI-PROJECT-18K19291
[Presentation] 間葉系幹細胞の重力感知における機械刺激受容チャンネルTRPV4を介したシグナル伝達経路の役割2018
- Author(s)
  加藤信靖,　田中瑞奈,　曽我部正博,　小林　剛
- Organizer
  日本宇宙生物科学会第32回大会
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] 間葉系幹細胞の足場の硬さ感知における機械刺激受容チャネルTRPV4を介したYAP活性化2018
- Author(s)
  田中瑞奈, 平野拓真, 曽我部正博, 小林剛
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] ワークショップ：ザ・メカノバイオロジー：分子から個体のメカノセンシング2017
- Author(s)
  曽我部正博、澤田康之、小林剛
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Gravi-sensing and -response in cultured mesenchymal stem cells2017
- Author(s)
  Sokabe M, Kobayashi T
- Organizer
  2nd Japan / French Symposium on Space Nutrition
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Unloading induces reactive oxygen sprecies associated signal transduction toward atrophy in skeletal muscle cells2017
- Author(s)
  Nikawa T, Uchida T, Kobayashi T, Sokabe M
- Organizer
  3rd International Symposium on Mechanobiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] 微小重力環境における間葉系幹細胞のYAP/TAZの活性化抑制機構2016
- Author(s)
  小林　剛, 橋爪藤子，田中瑞奈, 丸山昭洋, 東端　晃, 矢野幸子, 成瀬恵治, 二川　健, 曽我部正博
- Organizer
  日本宇宙生物科学会第30回大会
- Place of Presentation
  愛知医科大学たちばなホール・講義室（愛知県長久手市）
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] Possible Mechanisms for Gravity Sensing in Single Cells2016
- Author(s)
  Sokabe M, Kobayashi T
- Organizer
  11th Asian Microgravity Symposium (AMS2016)
- Place of Presentation
  Hokkaido University (Sapporo, Hokkaido)
- Year and Date
  2016-10-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] Cellular Active Touch Sensing of Substrate Rigidity2016
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  5th Nagoya Biomimetics International Symposium
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2016-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Initial Step of Gravi-Sensing in Mesenchymal Stem Cells2016
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  the 13th Korea-Japan Joint Seminar on Space Environment Utilization Research
- Place of Presentation
  Hokkaido University (Sapporo, Hokkaido)
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 微小重力環境における間葉系幹細胞のYAP/TAZの活性化抑制機構2016
- Author(s)
  小林　剛、橋爪藤子、田中瑞奈、丸山昭洋、東端　晃、矢野幸子、成瀬恵治、二川　建、曽我部正博
- Organizer
  第62回日本宇宙航空環境医学会大会・日本宇宙生物科学会第30回大会
- Place of Presentation
  愛知県
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Loss of Rigidity Sensing of Mesenchymal Stem Cells under Microgravity2016
- Author(s)
  Kobayashi T, Tanaka M, Hashizume T, Higashibata A, Yano S, Nikawa T, Sokabe M
- Organizer
  11th Asian Microgravity Symposium (AMS2016)
- Place of Presentation
  Hokkaido University (Sapporo)
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] ストレス線維の張力低下により誘導された接着斑解体におけるエンドサイトーシスの役割2016
- Author(s)
  田中瑞奈, 齋木貴博, 島本祐哉, 曽我部正博, 小林　剛
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Loss of Rigidity Sensing of Mesenchymal Stem Cells under Microgravity2016
- Author(s)
  Kobayashi T, Tanaka M, Hashizume T, Higashibata A, Yano S, Nikawa T, Sokabe M
- Organizer
  11th Asian Microgravity Symposium (AMS2016)
- Place of Presentation
  Hokkaidou, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] ストレス線維の張力低下により誘導された接着斑解体におけるエンドサイトーシスの役割2016
- Author(s)
  田中瑞奈, 齋木貴博, 島本祐哉, 曽我部正博, 小林　剛
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 模擬微小重力環境においた間葉系幹細胞のYAP/TAZの活性化抑制2016
- Author(s)
  小林　剛, 橋爪藤子, 田中瑞奈, 丸山昭洋, 東端　晃, 矢野幸子, 成瀬恵治, 二川　健, 曽我部正博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] 模擬微小重力環境においた間葉系幹細胞のYAP/TAZの活性化抑制2016
- Author(s)
  小林　剛, 橋爪藤子, 田中瑞奈, 丸山昭洋, 東端　晃, 矢野幸子, 成瀬恵治, 二川　健, 曽我部正博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 微小重力環境における間葉系幹細胞のYAP/TAZの活性化抑制機構2016
- Author(s)
  小林　剛, 橋爪藤子，田中瑞奈, 丸山昭洋, 東端　晃, 矢野幸子, 成瀬恵治, 二川　健, 曽我部正博
- Organizer
  日本宇宙生物科学会第30回大会
- Place of Presentation
  愛知医科大学たちばなホール・講義室（愛知県長久手市）
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Loss of Rigidity Sensing of Mesenchymal Stem Cells under Microgravity2016
- Author(s)
  Kobayashi T, Tanaka M, Hashizume T, Higashibata A, Yano S, Nikawa T, Sokabe M
- Organizer
  11th Asian Microgravity Symposium
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Possible Mechanisms for Gravity Sensing in Single Cells2016
- Author(s)
  Sokabe M, Kobayashi T
- Organizer
  11th Asian Microgravity Symposium (AMS2016)
- Place of Presentation
  Hokkaido University (Sapporo)
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Cellular Active Touch Sensing of Substrate Rigidity2016
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  the 13th Korea -Japan Joint Seminar on Space Environment Utilization Research
- Place of Presentation
  Hokkaido University (Sapporo)
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Initial Step of Gravi-Sensing in Mesenchymal Stem Cells2016
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  the 13th Korea -Japan Joint Seminar on Space Environment Utilization Research, Hokkaido University, Graduate School of Engineering
- Place of Presentation
  Sapporo, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] ストレス線維の張力低下により誘導された接着斑解体におけるエンドサイトーシスの役割2016
- Author(s)
  田中瑞奈、齋木貴博、島本祐哉、曽我部正博、小林　剛
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Cellular Active Touch Sensing of Substrate Rigidity2016
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  5th Nagoya Biomimetics International Symposium
- Place of Presentation
  Nagoya institute of Technology (Nagoya, Aichi)
- Year and Date
  2016-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] Loss of Rigidity Sensing of Mesenchymal Stem Cells under Microgravity2016
- Author(s)
  Kobayashi T, Tanaka M, Hashizume T, Higashibata A, Yano S, Nikawa T, Sokabe M
- Organizer
  11th Asian Microgravity Symposium (AMS2016)
- Place of Presentation
  Hokkaido University (Sapporo, Hokkaido)
- Year and Date
  2016-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 細胞の微小重力感知におけるストレス線維の張力の関与2015
- Author(s)
  小林　剛、橋爪藤子、東端　晃、矢野幸子、二川　健、曽我部正博
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド･兵庫
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] 動物細胞における微小重力環境センシング機構2015
- Author(s)
  小林　剛, 曽我部正博
- Organizer
  日本宇宙生物科学会第29回大会
- Place of Presentation
  帝京大学板橋キャンパス(東京都板橋区)
- Year and Date
  2015-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 細胞の微小重力感知におけるストレス線維の張力の関与2015
- Author(s)
  小林　剛、橋爪藤子、東端　晃、矢野幸子、二川　健、曽我部正博
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 動物細胞における微小重力環境センシング機構2015
- Author(s)
  小林　剛, 曽我部正博
- Organizer
  日本宇宙生物科学会第29回大会　シンポジウム5　「重力感知のメカノバイオロジー」
- Place of Presentation
  帝京大学板橋キャンパス･東京
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Cellular Substrate Rigidity Sensing: Possible Role of Mechanosensitive Ion Channels with Stress Fibers and Focal Adhesions2012
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  International Symposium on Innovative Nanobiodevices 2012 (ISIN 2012)
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] 細胞骨格に働く張力を利用した細胞の微小重力環境感知の分子モデル2012
- Author(s)
  小林剛、近藤茂忠、二川健、曽我部正博
- Organizer
  日本宇宙生物科学会第26回大会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] 細胞骨格に働く張力を利用した細胞の微小重力環境感知の分子モデル2012
- Author(s)
  小林剛、近藤茂忠、二川健、曽我部正博
- Organizer
  日本宇宙生物科学会第26回大会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Cellular Substrate Rigidity Sensing : Possible Role of Mechanosensitive Ion Channels with Stress Fibers and Focal Adhesions2012
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  International Symposium on Innovative Nanobiodevices 2012 (ISIN 2012) Toyoda Auditorium (Nagoya Univ.)
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] 細胞骨格に働く張力を利用した細胞の微小重力環境感知の分子モデル2012
- Author(s)
  小林剛、近藤茂忠、二川健、曽我部正博
- Organizer
  第26回日本宇宙生物科学会大会
- Place of Presentation
  阿波観光ホテル(徳島市)
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] Sensing Substrate Rigidity by Mechanosensitive Ion Channels with Stress Fibers and Focal Adhesions2011
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  International Symposium on Mechanobiology (the 5th Shanghai International Conference on Biophysics and Molecular Biology), Mini Symposium I
- Place of Presentation
  Shanghai-Hangzhou, China
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] Sensing the substrate rigidity: possible roles of stress fibers, focal adhesion and mechanosensitive channel2011
- Author(s)
  Kobayashi T, Tanaka M, Takeda Y, Ito G, Sokabe M
- Organizer
  8th International Congress on Comparative Physiology and Biochemistry (ICCPB 2011)
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] Sensing Substrate Rigidity by Mechanosensitive Ion Channels with Stress Fibers and Focal Adhesions2011
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  International Symposium on Mechanobiology (the 5th Shanghai International Conference on Biophysics and Molecular Biology)(招待講演)
- Place of Presentation
  Shanghai-Hangzhou, China
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] Sensing the substrate rigidity : possible roles of stress fibers, focal adhesion and mechanosensitive channel2011
- Author(s)
  Kobayashi T, Tanaka M, Takeda Y, Ito G, Sokabe M
- Organizer
  8th International Congress on Comparative Physiology and Biochemistry (ICCPB 2011)
- Place of Presentation
  Nagoya Congress Center, Nagoya
- Data Source
  KAKENHI-PROJECT-23612002
[Presentation] 細胞-基質接着部位におけるメカノトランスダクション:受動力覚から能動力覚へ機械的ストレスの感知と疾患2010
- Author(s)
  曽我部正博、早川公英、小林剛、辰巳仁史
- Organizer
  BMB2010(第83回日本生化学会大会・第33回日本分子生物学会年会合同大会ワークショップ1W6)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20570152
[Presentation] 細胞-基質接着部位におけるメカノトランスダクション:受動力覚から能動力覚へ2010
- Author(s)
  曽我部正博, 早川公英, 小林剛, 辰巳仁史
- Organizer
  BMB2010(第83回日本生化学会大会・第33回日本分子生物学会年会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20570152
[Presentation] Single molecule imaging of signaling molecules and ion channels in living cells.2009
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  The 36th International Congress of Physiological Science, Satellite Symposium #8
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20570152
[Presentation] Single molecule imaging of signaling molecules and ion channels in living cells.2009
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  The 36th International Congress of Physiological Science, Satellite Symposium #8 : Cardiac Electro-mechanical function, Cell-Organ Cross-Talk Revealed via Integration of Experiments and Models.
- Place of Presentation
  Naoshima, Kagawa
- Data Source
  KAKENHI-PROJECT-20570152
[Presentation] Ligand- or flow-induced up-regulation of cell surface P2X4 channels2008
- Author(s)
  Takeshi, Kobayashi, Fernando, Lopez-Redondo, Yoshie, Takeda, Mizuna, Tanaka, Kishio, Furuya, Kimiko, Yamamoto, Joji, Ando, Masahiro, Sokabe
- Organizer
  The 85th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] Flow-induced up-regulation of cell surface P2X4 channels.2008
- Author(s)
  小林剛、Fernando Lopez-Redondo、武田美江、田中瑞奈、古家喜四夫、山本希美子、安藤譲二、曽我部正博
- Organizer
  第BMB2008(第81回日本生化学会大会・第31回日本分子生物学会年会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20570152
[Presentation] 流れ刺激により誘導されるP2X4チャネルの細胞膜への移行2008
- Author(s)
  小林剛、Fernando Lopez-Redondo、武田美江、田中瑞奈、古家喜四夫、山本希美子、安藤譲二、曽我部正博
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20570152
[Presentation] 流れ刺激により誘導されるP2X4チャネルの細胞膜への移行2008
- Author(s)
  小林剛, 他7名
- Organizer
  BMB2008 (第81回日本生化学会大会・第31回日本分子生物学会年会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20570152
[Presentation] リガンドや流れ刺激により誘導されるP2X4チャネルの細胞膜への移行2008
- Author(s)
  小林剛
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] Targeting of Stretch-Activated BKca Channels to Focal Contacts of Cell Membrane via Two Distinct Mechanisms2007
- Author(s)
  Takeshi, Kobayashi, Yoshie, Takeda, Mizuna, Tanaka, Keiji, Naruse, Masahiro, Sokabe
- Organizer
  The 84th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] Single Molecule Imaging of SHOC2, Ras-scaffolding protein, in the Plasma Membrane of Living Cells2007
- Author(s)
  Mizuna, Tanaka, Yoshie, Takeda, Masahiro, Sokabe, Takeshi, Kobayashi
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] Immobilization of Stretch-Activated BKca channels to focal contacts of cell membrane as studied by single fluorophore video imaging2007
- Author(s)
  Takeshi, Kobayashi, Yoshie, Takeda, Mizuna, Tanaka, Keiji, Naruse, Masahiro, Sokabe
- Organizer
  The 45th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] 細胞接着部位へ停留する膜伸展依存性BKチャネルの1分子可視化解析2007
- Author(s)
  小林剛
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] 膜伸展依存性BKチャネルは2つの機構により細胞接着部位へ集積する2007
- Author(s)
  小林剛
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] Single Molecule Imaging of Stretch-Activated BKca Channels on the Plasma Membrane of Cultured Cells : Immobilization on Focal Contacts2006
- Author(s)
  Takeshi, Kobayashi, Yoshie, Takeda, Keiji, Naruse, Masahiro, Sokabe
- Organizer
  EABS&BS12006
- Place of Presentation
  Okinawa
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] 膜伸展依存性BKチャネルは細胞接着部位で停留する2006
- Author(s)
  小林剛
- Organizer
  第58回日本生理学会中国四国地方会
- Place of Presentation
  岡山
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] 膜伸展依存性BKチャネルの1分子イメージング:細胞接着部位での停留2006
- Author(s)
  小林剛
- Organizer
  EABS & BSJ2006
- Place of Presentation
  沖縄
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] Single Molecule Imaging of Stretch-Activated BKca Channels on the Plasma Membrane of Cultured Cells : Immobilization on Focal Contacts2006
- Author(s)
  Takeshi, Kobayashi, Yoshie, Takeda, Keiji, Naruse, Masahiro, Sokabe
- Organizer
  The 58th Chugoku-Shikoku Regional Chapter of Physiological Society of Japan
- Place of Presentation
  Okayama
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570151
[Presentation] 細胞の微小重力感知におけるストレス線維の張力の関与
- Author(s)
  小林　剛、橋爪藤子、東端　晃、矢野幸子、二川　健、曽我部正博
- Organizer
  第28回日本宇宙生物科学会大会
- Place of Presentation
  大阪府立大学中百舌鳥キャンパス、大阪府堺市中区学園町
- Year and Date
  2014-09-22 – 2014-09-23
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 細胞の微小重力感知におけるストレス線維の張力の関与
- Author(s)
  小林　剛、橋爪藤子、東端　晃、矢野幸子、二川　健、曽我部正博
- Organizer
  第28回日本宇宙生物科学会大会
- Place of Presentation
  大阪府立大学(中百舌鳥キャンパス)、大阪
- Year and Date
  2014-09-22 – 2014-09-23
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] 細胞メカニクス・システム：アクティブタッチによる基質の硬さ感知
- Author(s)
  小林　剛、曽我部正博
- Organizer
  第63回高分子討論会
- Place of Presentation
  2014年9月24日－26日長崎大学文教キャンパス、長崎
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Roles of stress fiber tension in gravity sensing of mesenchymal stem cells
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  International Symposium on Mechanobiology 2014, Symposium 4 Possible involvement of mechanosensitive systems in sensing and responding to changes in gravity.
- Place of Presentation
  Okayama University J-Hall, Okayama City, Okayama
- Year and Date
  2014-05-20 – 2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] Roles of stress fiber tension in gravity sensing of mesenchymal stem cells
- Author(s)
  Kobayashi T, Sokabe M
- Organizer
  International Symposium on Mechanobiology 2014, Symposium 4 Possible involvement of mechanosensitive systems in sensing and responding to changes in gravity.
- Place of Presentation
  Okayama University J-Hall, Okayama
- Year and Date
  2014-05-20 – 2014-05-23
- Data Source
  KAKENHI-PLANNED-24120007
[Presentation] Mechanotransduction by cytoskeleton-regulated MS channels at cell-substrate adhesion
- Author(s)
  Sokabe M, Kobayashi T
- Organizer
  International Symposium on Mechanobiology 2014, Symposium 1 Mechanosensitive channels and proteins 1
- Place of Presentation
  Okayama University J-Hall, Okayama City, Okayama
- Year and Date
  2014-05-20 – 2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26506009
[Presentation] 細胞メカニクス・システム：アクティブタッチによる基質の硬さ感知
- Author(s)
  小林　剛、曽我部正博
- Organizer
  第63回高分子討論会　特定テーマS18　「生物模倣による新規機能性材料・次世代型プロセスの創成」
- Place of Presentation
  長崎大学文教キャンパス、長崎県長崎市文教町
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26506009

1. SOKABE Masahiro (10093428)

# of Collaborated Projects: 5 results

# of Collaborated Products: 20 results
2. NIKAWA Takeshi (20263824)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. Liu Hao (40303698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KAZAKI RYOHEI (40221907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. AONO HIKARU (10623712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TANAKA HIROTO (80624725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. NAKATA TOSHIYUKI (80793190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MUROSAKI TAKAYUKI (90526831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUZUKI Yutaka (40323646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TATSUMI Hitoshi (20171720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HAYAKAWA Kimihide (60467280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Naruse Keiji (40252233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 木戸秋悟 (10336018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 山崎剛史 (70390755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 安藤規泰 (70436591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高橋賢 (50432258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 東谷篤志 (40212162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 平坂勝也 (70432747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 清島大資 (80756370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 縣信秀 (00549313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. 伊東佑太 (30454383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 古家喜四夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 冨田拓郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 中尾玲子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 奥村裕司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 増田章男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOBAYASHI Takeshi 小林 剛

Research Projects

Research Products

Co-Researchers

Imaging analysis of ER-mitochondria contact sites in living cellsPrincipal Investigator

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Analysis of mechanosensing/transduction in costamere by ultrasound

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Mechano-nutrition-signaling for disuse muscle atrophy

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Imaging analysis of mechno-sensing in mitochondria of living cellsPrincipal Investigator

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Mechanosensing Mechanisms for Sensing Mechanical Stress Including Gravitational Changes

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Initial step of gravity sensing in cultured animal cellsPrincipal Investigator

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Bio-inspired Mechanical Systems

Principal Investigator

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Mitochondria is a key signal inducer for unloading stress toward muscle atrophy

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Possible roles of actomyosin and mechanosensitive channels in substrate rigidity sensing of cells

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Dynamics of myristoylated amino-terminal domain of Src in the plasma membrane of mechano-stimulated cells studied by single molecule imagingPrincipal Investigator

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IMAGING ANALYSIS OF CELL SURFACE P2X4 RECEPTOR UP-REGULATED BY FLOW SHEAR STRESSPrincipal Investigator

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ANALYSES OF MOLECULAR MECHANISM OF STRETCH-ACTIVATED CHANNELS USING SINGIPrincipal Investigator

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[Book] “再生医工学におけるメカノバイオロジーII:創傷治癒/基質高度検知/基質工学” 曽我部 正博 編集『メカノバイオロジー：細胞が力を感じ応答する仕組み』(第22章)2015

Author(s)

Total Pages

Publisher

KOBAYASHI Takeshi 小林剛

[Book] “再生医工学におけるメカノバイオロジーII:創傷治癒/基質高度検知/基質工学” 曽我部正博編集『メカノバイオロジー：細胞が力を感じ応答する仕組み』(第22章)2015

[Book] ベーシックマスター細胞生物学(「細胞膜」神谷律、尾張部克志編集第5章)2009