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KANKI SACHIKO  神吉 佐智子

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… Alternative Names

KANKI Sachiko  神吉 佐智子

HORIMOTO Sachiko  堀本 佐智子

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Researcher Number 40411350
External Links
Affiliation (Current) 2025: 大阪医科薬科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2023: 大阪医科薬科大学, 医学部, 講師
2020: 大阪医科大学, 医学部, 講師
2011 – 2019: 大阪医科大学, 医学部, 助教
2005 – 2006: 大阪医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Cardiovascular surgery / Thoracic surgery
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Cardiovascular surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Thoracic surgery
Keywords
Principal Investigator
心筋保護治療 / 虚血再灌流傷害 / 虚血性心筋症 / ペプチド創薬 / 心筋虚血 / 心筋細胞 / 虚血性心不全 / ペプチド / アンチセンス医薬 / 組織標的ペプチド … More / 薬物送達 / 病変標的治療薬 / 心筋虚血傷害 / 組織標的治療 / 心臓虚血再灌流障害 / 虚血組織送達 / 低酸素培養 / 虚血 / 組織特異的ペプチド / 質量分析 / 遺伝子導入 / 培養心筋細胞 / プロテオーム解析 / 培養細胞 / ホーミングペプチド / 心筋虚血再灌流傷害 / アフィニティー精製 / アフィニティ精製 … More
Except Principal Investigator
大動脈解離 / 血管細胞モデル / Marfan症候群 / 再生医療 / 脂肪由来幹細胞 / 遺伝性結合組織疾患 / 人工多能性幹細胞 / 微小領域RNAシークエンス / 細胞外基質 / モデルマウス / 電顕 / 結合実験 / シグナリング / シンクロトロンイメージング / ハイブリッドドメイン / 弾性線維 / マウスモデル / ミクロフィブリル / ドラッグ・リポジショニング / 稀少難病 / マルファン症候群 / 平滑筋細胞 / iPS細胞 / 再生医学 / pulmonary hypertension / synthetic vascular prosthesis / gene transduction / eNOS / bone marrow cells / ハイブリッド / 骨髄間質系細胞 / 肺高血圧症 / 人工血管 / 遺伝子導入 / eNOS遺伝子 / 骨髄細胞 / 脂肪組織由来間葉系幹細胞 / 心不全 / 心筋組織由来間葉系幹細胞 / 虚血性心筋症 Less
  • Research Projects

    (11 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (14 People)
  •  虚血心筋標的ペプチドを用いたアンチセンス医薬による心筋保護治療の開発Principal Investigator

    • Principal Investigator
      神吉 佐智子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  The cell-based vascular model with the inducible pluripotent stem cells of Marfan syndrome.

    • Principal Investigator
      大門 雅広
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  Elucidation of the pathogenesis of aortic dissection caused by the alteration in microfibrils

    • Principal Investigator
      柳沢 裕美
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      University of Tsukuba
  •  The development of Cardioprotection therapy with ischemic myocardium-homing peptide along with revascularizationPrincipal Investigator

    • Principal Investigator
      Kanki Sachiko
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  The drug screening for individuals of Marfan syndrome using the in vitro vascular cell model made from patient-derived iPS cells

    • Principal Investigator
      Daimon Masahiro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  Treatment of ischemic heart failure using human adipose-derived stem cells

    • Principal Investigator
      Katsumata Takahiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Osaka Medical College
  •  The development of new drugs with ischemic myocardium targeting peptidesPrincipal Investigator

    • Principal Investigator
      KANKI SACHIKO
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Osaka Medical College
  •  The cardiovascular regeneration therapy with human pericardiac adipose tissue derived stem cells

    • Principal Investigator
      Katsumata Takahiro
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Osaka Medical College
  •  The drug delivery application of the ischemic myocardium targeting peptidePrincipal Investigator

    • Principal Investigator
      Kanki Sachiko
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Osaka Medical College
  •  Tissue-selective heart failure treatment with the ischemic heart-homing peptidePrincipal Investigator

    • Principal Investigator
      KANKI Sachiko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Thoracic surgery
    • Research Institution
      Osaka Medical College
  •  In Vivo Evaluation of Small Caliber Vascular Prosthesis Impregnated with Bone Marrow Cells Overexpressing eNOS.

    • Principal Investigator
      KATSUMATA Takahiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Osaka Medical College

All 2022 2021 2006 2005

All Journal Article Presentation

  • [Journal Article] Implantation of Mesenchymal stem cells overexpressing endothelial nitric oxide synthase improved right ventricular impairments caused by pulmonary hypertension.2006

    • Author(s)
      Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E, Katsumata T.
    • Journal Title

      Circulation 114-1

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Synthetic vascular prosthesis impregnated with Mesenchymal stem cells overexpressing endothelial nitric oxide synthase.2006

    • Author(s)
      Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E, Katsumata T.
    • Journal Title

      Circulation 114-1

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Hybrid cell therapy with bone marrow cells overexpressing nitric oxide synthase.2006

    • Author(s)
      Horimoto S.
    • Journal Title

      J Osaka Medical College 65-2

      Pages: 91-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improved right ventricular impairments caused by pulmonary hypertension.2006

    • Author(s)
      Sachiko Kanki-Horimoto
    • Journal Title

      Circulation 114・1suppl

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] 一酸化窒素合成酵素遺伝子導入骨髄細胞を用いた細胞療法2006

    • Author(s)
      堀本佐智子
    • Journal Title

      大阪医科大学雑誌 65・2

      Pages: 91-93

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Synthetic vascular prosthesis impregnated with mesenchymal stem cells overexpressing endothelial nitric oxide synthase.2006

    • Author(s)
      Sachiko Kanki-Horimoto
    • Journal Title

      Circulation 114・1suppl

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Synthetic Vascular Prosthesis Impregnated with Genetically Modified Bone Marrow Cells Produced Recombinant Proteins2005

    • Author(s)
      Sachiko Kanki-Horimoto
    • Journal Title

      Artificial Organs 29・10

      Pages: 8195-8819

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Synthetic Vascular Prosthesis Impregnated with Genetically Modified Bone Marrow Cells Produced Recombinant Proteins2005

    • Author(s)
      堀本佐智子
    • Journal Title

      Artificial Organs 29・10

      Pages: 815-819

    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Synthetic vascular prosthesis impregnated with genetically modified bone marrow cells produced recombinant proteins.2005

    • Author(s)
      Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E, Katsumata T.
    • Journal Title

      Artificial Organs 29-10

      Pages: 815-819

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Presentation] マルファン症候群モデルマウスを用いた大動脈解離発症メカニズムの解明2022

    • Author(s)
      木村健一、本山絵理、石井柳太郎、杉山夏緒里、山城義人、神吉佐智子、柳沢裕美
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] A novel mouse model of aortic dissection caused by a point mutation in the hybrid domain of the fibrillin-1 gene2022

    • Author(s)
      Kenichi Kimura, Eri Motoyama, Ryutaro Ishii, Kaori Sugiyama, Yoshito Yamashiro, Violette Deleeuw, Patrick Sips, Julie De Backer, Laura Muino-Mosquera, Lynn Y. Sakai, Sachiko Kanki, Hiromi Yanagisawa
    • Organizer
      11th International Symposium on Marfan, Loeys-Dietz, and Related Conditions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] 新規Fbn1遺伝子変異マウスを用いたマルファン症候群の大動脈解離発症機序の解明2021

    • Author(s)
      本山絵理、木村健一、石井柳太郎、杉山夏緒里、山城義人、神吉佐智子、柳沢裕美
    • Organizer
      エラスチン・関連分子研究会学術集会
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • 1.  WATANABE Fusao (40183719)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 3 results
  • 2.  MIENO Shigetoshi (10411373)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  Katsumata Takahiro (60224474)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 4.  Daimon Masahiro (20388268)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  伊井 正明 (10442922)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  打田 裕明 (70736834)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  福原 慎二 (70764984)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  友田 紀一郎 (50362843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  柳沢 裕美 (40746301)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 10.  杉山 夏緒里 (20889662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  木村 健一 (50633153)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  石井 柳太郎 (90907669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  森原 啓文 (40802674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  斯波 真理子 (70271575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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