Ito-Ishida Aya 石田綾

Researcher Number	40424171
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2020 – 2024: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームリーダー 2018 – 2021: 慶應義塾大学, 医学部(信濃町), 講師 2017: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Transformative Research Areas, Section (III) / Complex systems / Nerve anatomy/Neuropathology Except Principal Investigator Basic Section 46010:Neuroscience-general-related / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator シナプス / 発達障害 / 小脳 / 神経科学 / 脳発達 / Cbln / 領野連関 / 前頭前野 / DNAメチル化 / 大脳 … More / ネットワーク / 広域脳活動 / 行動変容 / 発達障害モデル / 自閉スペクトラム症（ASD） / Cblnファミリー / 疼痛 / 痛み刺激 / 可塑性 / Cblnファミリー分子 / 神経活動 / 自閉スペクトラム症 / 脳神経疾患 / 解剖学 / 生理学 / MeCP2 / レット症候群 … More Except Principal Investigator Split-TurboID / 顆粒細胞 / プロテオーム / プルキンエ細胞 / 分子 / ドーパミン / 神経回路 / TurboID / 近位依存性ビオチン標識 / シナプス / 小脳 / BioID / RNA therapeutics / Autism spectrum disorder / Brain development / Circular RNAs Less

Diagnostic and Therapeutic Potential of Circular RNAs in Autism Spectrum Disorder
- Principal Investigator
  
  Gailhouste Luc
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Institute of Physical and Chemical Research
発達障害モデルマウスにおける皮質間シナプスの障害とそのメカニズムの解明Principal Investigator
- Principal Investigator
  
  石田綾
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Institute of Physical and Chemical Research
発達とその障害における行動変容と広域脳動態の解明Principal Investigator
- Principal Investigator
  
  石田綾
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Physical and Chemical Research
Comprehensively identification of molecules at synapses and non-synaptic cell-adhesion structure
- Principal Investigator
  
  高野哲也
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kyushu University
  Keio University
The roles of Cbln-family proteins in activity-induced neuronal circuit changesPrincipal Investigator
- Principal Investigator
  
  Ito-Ishida Aya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Institute of Physical and Chemical Research
  Keio University
Elucidating Functional Connectivity between Cerebellum and Prefrontal CortexPrincipal Investigator
- Principal Investigator
  
  石田綾
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Institute of Physical and Chemical Research
  Keio University
発達障害の病態理解に向けた小脳－前頭前野－領野連関の解明Principal Investigator
- Principal Investigator
  
  石田綾
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Keio University
レット症候群における小脳神経回路異常の解明Principal Investigator
- Principal Investigator
  
  石田綾
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Keio University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] 精神医学領域の論文を読みこなすキーワード100！2023
- Author(s)
  鬼塚俊明編著　石田綾　（分担著者）
- Total Pages
  3
- Publisher
  新興医学出版社
- ISBN
  9784880028866
- Data Source
  KAKENHI-PLANNED-22H05158
[Journal Article] 特集シナプス Ⅰ.シナプス発生:形成と成熟単一遺伝子疾患からアプローチする神経発達障害2023
- Author(s)
  石田綾
- Journal Title
  
  生体の科学
  
  Volume: 74 Issue: 1 Pages: 23-26
- DOI
  10.11477/mf.2425201634
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2023-02-15
- Data Source
  KAKENHI-PLANNED-22H05158
[Journal Article] Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia2020
- Author(s)
  Ward Christopher S.、Huang Teng-Wei、Herrera Jose A.、Samaco Rodney C.、McGraw Christopher M.、Parra Diana E.、Arvide E. Melissa、Ito-Ishida Aya、Meng Xiangling、Ure Kerstin、Zoghbi Huda Y.、Neul Jeffrey L.
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 11
- DOI
  10.3389/fneur.2020.593554
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Journal Article] 自閉スペクトラム症と小脳2020
- Author(s)
  石田綾
- Journal Title
  
  生体の科学
  
  Volume: 72 Pages: 74-77
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Journal Article] MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons2020
- Author(s)
  Ito-Ishida Aya、Baker Steven A.、Sillitoe Roy V.、Sun Yaling、Zhou Jian、Ono Yukiteru、Iwakiri Junichi、Yuzaki Michisuke、Zoghbi Huda Y.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 40 Issue: 45 Pages: 8746-8766
- DOI
  10.1523/jneurosci.1281-19.2020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12041, KAKENHI-PUBLICLY-20H05071, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20H05628
[Journal Article] Improvement of cerebellar ataxic gait by injecting Cbln1 into the cerebellum of cbln1-null mice2018
- Author(s)
  E. Takeuchi，A. Ito-Ishida，M. Yuzaki，D. Yanagihara
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 6184-6184
- DOI
  10.1038/s41598-018-24490-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0015, KAKENHI-PROJECT-18K10955, KAKENHI-PUBLICLY-18H05139, KAKENHI-PROJECT-15H05772, KAKENHI-PROJECT-16H06276
[Journal Article] Genome Wide Distribution of Linker Histone H1.0 is Independent of MeCP2. Nature Neuroscience.2018
- Author(s)
  Ito-Ishida A, Yamalanchili HK, Shao Y, Baker SA, Heckman LD, Lavery LA, Kim J, Lombardi LM, Sun Y, Liu Z, Zoghbi HY.
- Journal Title
  
  Nature Neuroscience
  
  Volume: 21 Issue: 6 Pages: 794-798
- DOI
  10.1038/s41593-018-0155-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05139, KAKENHI-PROJECT-16H06276
[Presentation] Dissecting the mechanisms of behavioral changes in developmental disorders2023
- Author(s)
  Ito-Ishida, Aya
- Organizer
  The 1st International Symposium of “Biology of Behavior Change”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05158
[Presentation] Connecting Molecules and Circuitry to Untangle Developmental Disorders2022
- Author(s)
  Aya Ito-Ishida
- Organizer
  RIKEN CBS and Monash BDI joint symposium,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] Connecting Molecules and Circuitry to Untangle Developmental Disorders2022
- Author(s)
  Aya Ito-Ishida
- Organizer
  RIKEN CBS and Monash BDI joint symposium,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] Understanding cortical dynamics that underlie behavioral changes in developmental disorders2022
- Author(s)
  Ito-Ishida, Aya
- Organizer
  学術変革A 『行動変容生物学』第1回領域会議東京
- Invited
- Data Source
  KAKENHI-PLANNED-22H05158
[Presentation] Connecting Molecules and Circuitry to Untangle Developmental Disorders2022
- Author(s)
  Aya Ito-Ishida
- Organizer
  RIKEN CBS Retreat
- Invited
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] Connecting Molecules and Circuitry to Untangle Developmental Disorders2022
- Author(s)
  Aya Ito-Ishida
- Organizer
  RIKEN CBS Retreat
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] レット症候群の病態メカニズム2022
- Author(s)
  石田綾
- Organizer
  生理研シンポジウム「幼・小児の成長期における脳機能と運動の発達に関する多領域共同研究」生理学研究所（Hybrid）
- Invited
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] 発達期の行動変容を支える新規メカニズムの解明2022
- Author(s)
  石田綾
- Organizer
  次世代脳合同シンポジウム2022: 神経回路研究の新潮流
- Invited
- Data Source
  KAKENHI-PLANNED-22H05158
[Presentation] Understanding the pathogenesis of Rett syndrome from multiple perspectives2022
- Author(s)
  Ito-Ishida, Aya
- Organizer
  RIKEN CBS-KIST BSI Joint Symposium
- Invited
- Data Source
  KAKENHI-PLANNED-22H05158
[Presentation] レット症候群の病態メカニズム2022
- Author(s)
  石田綾
- Organizer
  生理研シンポジウム「幼・小児の成長期における脳機能と運動の発達に関する多領域共同研究」生理学研究所（Hybrid）
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 発達障害の理解にむけて：分子と行動をつなぐアプローチ2022
- Author(s)
  石田綾
- Organizer
  第63回日本視能矯正学会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05158
[Presentation] Understanding brain development from molecules and behavior,2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  理化学研究所　第24回異文化交流の夕べ
- Invited
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] レット症候群の分子病態メカニズム2021
- Author(s)
  石田綾
- Organizer
  名古屋大学、若手新分野創成ワークショップ
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 早期ライフステージにおける神経回路形成機構の解明2021
- Author(s)
  石田綾
- Organizer
  AMED-Prime 「早期ライフ」領域会議
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] Connecting molecules and circuitry to untangle developmental disorders2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  第44回日本神経科学大会　CJK第1回国際会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 脳発達のメカニズム：二つの分子から見えてきた世界2021
- Author(s)
  石田綾
- Organizer
  第5回子どものこころの分子統御機構研究センター令和3年度連続セミナー& 大阪大学神経科学懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] Untangling Developmental Disorders：Perspectives from MeCP2 and Cbln12021
- Author(s)
  Aya Ito-Ishida
- Organizer
  RIKEN CBS Seminar
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] Advancing the understanding of developmental disorders2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  第44回日本神経科学大会　CJK第1回国際会議　（教育講演）
- Invited
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] 脳発達のメカニズム：二つの分子から見えてきた世界2021
- Author(s)
  石田綾
- Organizer
  第5回子どものこころの分子統御機構研究センター令和3年度連続セミナー& 大阪大学神経科学懇話会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] Clarification of Cerebello-Prefrontal Connection to Understand Developmental Disorders2021
- Author(s)
  石田綾
- Organizer
  『脳情報動態』領域会議、東京国際フォーラム（Hybrid）
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] Understanding brain development from molecules and behavior,2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  理化学研究所　第24回異文化交流の夕べ
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] Connecting molecules and circuitry to untangle developmental disorders2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  RIKEN CBS Summer Program 2021
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 早期ライフステージにおける神経回路形成機構の解明2021
- Author(s)
  石田綾
- Organizer
  AMED-Prime 「早期ライフ」領域会議
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] Connecting molecules and circuitry to untangle developmental disorders2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  第44回日本神経科学大会　CJK第1回国際会議
- Invited
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] Connecting molecules and circuitry to untangle developmental disorders.2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  IBRO-RIKEN CBS Summer Program 2021
- Data Source
  KAKENHI-PROJECT-20H03343
[Presentation] Advancing the understanding of developmental disorders2021
- Author(s)
  Aya Ito-Ishida
- Organizer
  第44回日本神経科学大会　CJK第1回国際会議　（教育講演）
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] MeCP2 Levels Regulate Heterochromatin Structure in vivo2020
- Author(s)
  Aya Ito-Ishida
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] Regulation of neuronal heterochromatin structure by MeCP22020
- Author(s)
  Aya Ito-Ishida
- Organizer
  UK-Japan Neuroscience Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] 発達障害の病態理解に向けた小脳-前頭前野領野連関の解明2020
- Author(s)
  石田綾
- Organizer
  『脳情報動態』領域会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 早期ライフステージにおける神経回路成熟機構の解明2020
- Author(s)
  石田綾
- Organizer
  令和2年度AMED-Prime「早期ライフ」研究開発領域キックオフ会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 脳の発達を支える新たなメカニズム‐MeCP2によるヘテロクロマチン制御‐2020
- Author(s)
  石田綾
- Organizer
  第71回日本薬理学会北部会、次世代薬理学セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 脳の発達を支える分子から精神神経疾患の理解へ2020
- Author(s)
  石田綾
- Organizer
  ３委員会合同企画市民公開講座 2050年の脳科学
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05071
[Presentation] 発達障害の病態理解に向けた小脳－前頭前野－領野連関の解明2019
- Author(s)
  石田綾
- Organizer
  新学術領域「脳情報動態」領域会議
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] 早期ライフステージにおける神経回路成熟機構の解明2019
- Author(s)
  石田綾
- Organizer
  AMED-Prime「早期ライフ」研究開発領域キックオフ会議
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] Understanding Postnatal Neurodevelopmental Disorders from Multiple Perspectives2019
- Author(s)
  Aya Ito-Ishida
- Organizer
  RIKEN CBS Summer Program 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] Clarification of connectivity between cerebellum and prefrontal cortex2019
- Author(s)
  石田綾
- Organizer
  新学術領域「脳情報動態」領域会議
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] MeCP2 Induces Structural Changes in Heterochromatin Independent of Linker Histone H1.0 Distribution2018
- Author(s)
  Aya Ito-Ishida
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] 神経細胞におけるMeCP2の役割2018
- Author(s)
  石田綾
- Organizer
  レット症候群とMECP2重複症候群の合同シンポジウム in Tokyo
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] Understanding the pathogenesis of Rett syndrome using multiple approaches2018
- Author(s)
  Aya Ito-Ishida
- Organizer
  第10回光操作研究会・第2回脳情報動態　合同国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] レット症候群の病態理解に向けて-マウスモデルによるアプローチ2018
- Author(s)
  石田綾
- Organizer
  東京大学精神科セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] 発達障害の病態理解に向けた小脳-前頭前野-領野連関の解明2018
- Author(s)
  石田綾
- Organizer
  新学術領域研究「脳情報動態を規定する多領野連関と並列処理」領域会議
- Data Source
  KAKENHI-PUBLICLY-18H05139
[Presentation] MeCP2 levels regulate neuronal chromatin structure in vivo,2018
- Author(s)
  石田綾
- Organizer
  第53回TOKYOニューロサイエンス研究会
- Data Source
  KAKENHI-PUBLICLY-18H05139

1. 石川理子 (60547991)

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2. 坂内博子 (40332340)

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3. Gailhouste Luc (40848537)

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4. 高野哲也 (00725541)

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5. 掛川渉 (70383718)

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6. 村田唯 (10802077)

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7. 柴田明子 (70964245)

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8. 柳原大

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9. 岩切淳一

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Ito-Ishida Aya 石田 綾

Research Projects

Research Products

Co-Researchers

Diagnostic and Therapeutic Potential of Circular RNAs in Autism Spectrum Disorder

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発達障害モデルマウスにおける皮質間シナプスの障害とそのメカニズムの解明Principal Investigator

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発達とその障害における行動変容と広域脳動態の解明Principal Investigator

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Comprehensively identification of molecules at synapses and non-synaptic cell-adhesion structure

Principal Investigator

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The roles of Cbln-family proteins in activity-induced neuronal circuit changesPrincipal Investigator

Principal Investigator

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Elucidating Functional Connectivity between Cerebellum and Prefrontal CortexPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

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発達障害の病態理解に向けた小脳－前頭前野－領野連関の解明Principal Investigator

Principal Investigator

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Research Institution

レット症候群における小脳神経回路異常の解明Principal Investigator

Principal Investigator

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Research Institution

[Book] 精神医学領域の論文を読みこなすキーワード100！2023

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[Journal Article] 特集 シナプス Ⅰ.シナプス発生:形成と成熟 単一遺伝子疾患からアプローチする神経発達障害2023

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[Journal Article] Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia2020

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[Journal Article] 自閉スペクトラム症と小脳2020

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[Journal Article] MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons2020

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DOI

Data Source

[Journal Article] Improvement of cerebellar ataxic gait by injecting Cbln1 into the cerebellum of cbln1-null mice2018

Author(s)

Ito-Ishida Aya 石田綾

[Journal Article] 特集シナプス Ⅰ.シナプス発生:形成と成熟単一遺伝子疾患からアプローチする神経発達障害2023