Takata Atsushi 高田篤

Researcher Number	90643693
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームディレクター 2020 – 2025: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームリーダー 2016 – 2019: 横浜市立大学, 医学部, 講師 2015: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員
Review Section/Research Field	Principal Investigator Psychiatric science / Medium-sized Section 46:Neuroscience and related fields / Basic Section 52030:Psychiatry-related / Transformative Research Areas, Section (III) Except Principal Investigator Basic Section 52030:Psychiatry-related / Transformative Research Areas, Section (III)
Keywords	Principal Investigator 統合失調症 / 遺伝統計 / サブシングルセル解像度 / 死後脳 / マウスモデル / 空間トランスクリプトミクス / 次世代シーケンサー / 体細胞変異 / 双極症 / 双極性障害 … More / エクソーム / 機械学習 / 精神神経疾患 / RNAシーケンス / マルチモーダル一細胞 / 調節エレメント / スプライシング / 発現制御 / QTL / GWAS / 神経科学 / 精神医学 / 遺伝学 / ゲノム / 選択的スプライシング / クロマチン / デノボ変異 … More Except Principal Investigator DOHaD / 統合失調症 / 脂質代謝 / 脳発達 / 低栄養 / PPAR-alpha / 栄養 / 脳発達期 / 領域会議 / ワークショップ / アウトリーチ / ネットワーク / 大脳新皮質 / ハブ細胞 / シンポジウム / 新規分野開拓 Less

Elucidation of Molecular Pathology of Schizophrenia Through Cross-Species Spatial Transcriptomics at Sub-Single-Cell ResolutionPrincipal Investigator
- Principal Investigator
  
  高田篤
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  Institute of Physical and Chemical Research
Mechanisms Linking Maternal Undernutrition to Schizophrenia Risk in Offspring via Metabolic Dysregulation
- Principal Investigator
  
  前川素子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tohoku University
Exploring the Mechanisms of Schizophrenia Induced by Malnutrition During Brain Development
- Principal Investigator
  
  前川素子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tohoku University
Comprehensive investigation of rare germline and somatic mutations in bipolar disorder by large-scale sequencing analysis.Principal Investigator
- Principal Investigator
  
  Takata Atsushi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Institute of Physical and Chemical Research
Morphological features and gene expression patterns underlying hub neurons
- Principal Investigator
  
  Murayama Masanori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Physical and Chemical Research
Identification of genes and key molecular pathways determining cluster/hub cells and analysis of their association with human diseasesPrincipal Investigator
- Principal Investigator
  
  Takata Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Physical and Chemical Research
Comprehensive analysis of splicing regulation and splicing quantitative trait loci (sQTL) in brains of major psychosesPrincipal Investigator
- Principal Investigator
  
  Takata Atsushi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Psychiatric science
- Research Institution
  Yokohama City University
Target resequencing of SETD1A, a strong candidate gene for schizophrenia with exome-wide significance, using the next generation sequencerPrincipal Investigator
- Principal Investigator
  
  高田篤
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Psychiatric science
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Transcriptomic dysregulation and autistic-like behaviors in Kmt2c haploinsufficient mice rescued by an LSD1 inhibitor2024
- Author(s)
  Nakamura Takumi、Yoshihara Toru、Tanegashima Chiharu、Kadota Mitsutaka、Kobayashi Yuki、Honda Kurara、Ishiwata Mizuho、Ueda Junko、Hara Tomonori、Nakanishi Moe、Takumi Toru、Itohara Shigeyoshi、Kuraku Shigehiro、Asano Masahide、Kasahara Takaoki、Nakajima Kazuo、Tsuboi Takashi、Takata Atsushi、Kato Tadafumi
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 29 Issue: 9 Pages: 2888
- DOI
  10.1038/s41380-024-02479-8
- URL
  https://localhost/en/publications/0fc5ec78-42d0-4aa0-9f03-8d267d764e27
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15752, KAKENHI-PROJECT-22H00468, KAKENHI-PROJECT-21H02855
[Journal Article] Topologically associating domains define the impact of de novo promoter variants on autism spectrum disorder risk2024
- Author(s)
  Nakamura Takumi、Ueda Junko、Mizuno Shota、Honda Kurara、Kazuno An-a、Yamamoto Hirona、Hara Tomonori、Takata Atsushi
- Journal Title
  
  Cell Genomics
  
  Volume: 4 Issue: 2 Pages: 100488-100488
- DOI
  10.1016/j.xgen.2024.100488
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15752, KAKENHI-PROJECT-22K20751, KAKENHI-PROJECT-21H02855
[Journal Article] A case of bipolar I disorder with a loss‐of‐function variant of schizophrenia risk gene <scp><i>SETD1A</i></scp>: possible expansion of the relevant clinical spectrum supported by a meta‐analysis2024
- Author(s)
  Hara Tomonori、Kazuno An‐a、Toyota Tomoko、Ueda Junko、Shuno Takehiko、Mukai Jun、Sato Taka‐Aki、Matsumoto Naomichi、Yoshikawa Takeo、Takata Atsushi
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: - Issue: 6 Pages: 374-375
- DOI
  10.1111/pcn.13669
- Data Source
  KAKENHI-PROJECT-21H02855
[Journal Article] Molecular diagnosis of 405 individuals with autism spectrum disorder2023
- Author(s)
  Miyake Noriko、Tsurusaki Yoshinori、Fukai Ryoko、Kushima Itaru...Takata Atsushi、Mizuguchi Takeshi、Ozaki Norio、Matsumoto Naomichi
- Journal Title
  
  European Journal of Human Genetics
  
  Volume: 27-Mar Issue: 12 Pages: 1-8
- DOI
  10.1038/s41431-023-01335-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-23K24308, KAKENHI-PROJECT-20K16625, KAKENHI-PROJECT-23K07254, KAKENHI-PROJECT-20K08265, KAKENHI-PROJECT-19K17061, KAKENHI-PLANNED-20H05777
[Journal Article] Deep exome sequencing identifies enrichment of deleterious mosaic variants in neurodevelopmental disorder genes and mitochondrial tRNA regions in bipolar disorder2023
- Author(s)
  Nishioka Masaki、Takayama Jun、Sakai Naomi、Kazuno An-a、Ishiwata Mizuho、Ueda Junko、Hayama Takashi、Fujii Kumiko、Someya Toshiyuki、Kuriyama Shinichi、Tamiya Gen、Takata Atsushi、Kato Tadafumi
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 28 Issue: 10 Pages: 4294-4306
- DOI
  10.1038/s41380-023-02096-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07500, KAKENHI-PROJECT-23K07021, KAKENHI-PROJECT-21K15722, KAKENHI-PROJECT-22H00468, KAKENHI-PROJECT-21H02855
[Journal Article] GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice2023
- Author(s)
  Yamamoto Hirona、Lee-Okada Hyeon-Cheol、Ikeda Masashi、Nakamura Takumi、Saito Takeo、Takata Atsushi、Yokomizo Takehiko、Iwata Nakao、Kato Tadafumi、Kasahara Takaoki
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 28 Issue: 7 Pages: 2848-2856
- DOI
  10.1038/s41380-023-01988-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-21K07490, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-23K24264, KAKENHI-PLANNED-20H05777
[Journal Article] The molecular pathology of schizophrenia: an overview of existing knowledge and new directions for future research2023
- Author(s)
  Nakamura Takumi、Takata Atsushi
- Journal Title
  
  Molecular Psychiatry
  
  Volume: N/A Issue: 5 Pages: 1868-1889
- DOI
  10.1038/s41380-023-02005-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15752, KAKENHI-PROJECT-21H02855, KAKENHI-PLANNED-20H05777
[Journal Article] Genetics of bipolar disorder: insights into its complex architecture and biology from common and rare variants2022
- Author(s)
  Hara Tomonori、Owada Yuji、Takata Atsushi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 3 Pages: 183-191
- DOI
  10.1038/s10038-022-01046-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02855, KAKENHI-PLANNED-20H05777
[Journal Article] Large-scale discovery of novel neurodevelopmental disorder-related genes through a unified analysis of single-nucleotide and copy number variants.2022
- Author(s)
  Hamanaka K, Miyake N, Mizuguchi T, Miyatake S, Uchiyama Y, Tsuchida N, Sekiguchi F, Mitsuhashi S, Tsurusaki Y, Nakashima M, Saitsu H, Yamada K, Sakamoto M, Fukuda H, Ohori S, Saida K, Itai T, Azuma Y, Koshimizu E, Fujita A, Erturk B, Hiraki Y, Ch'ng GS, Kato M, Okamoto N, Takata A, Matsumoto N.
- Journal Title
  
  Genome Med
  
  Volume: 14 Issue: 1 Pages: 40-40
- DOI
  10.1186/s13073-022-01042-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-20K08236, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-20K17936, KAKENHI-PLANNED-20H05777
[Journal Article] Exome sequencing analysis of Japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes2022
- Author(s)
  Kimura H, Okada T, Sebat J, et al.
- Journal Title
  
  Translational Psychiatry
  
  Volume: 12 Issue: 1 Pages: 265-265
- DOI
  10.1038/s41398-022-02033-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08044, KAKENHI-PROJECT-20K20602, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K17936, KAKENHI-PROJECT-21H02848, KAKENHI-PROJECT-23K24308, KAKENHI-PLANNED-20H05777
[Journal Article] Refinement of the clinical variant interpretation framework by statistical evidence and machine learning2021
- Author(s)
  Takata Atsushi、Hamanaka Kohei、Matsumoto Naomichi
- Journal Title
  
  Med
  
  Volume: - Issue: 5 Pages: 611-632.e9
- DOI
  10.1016/j.medj.2021.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05777
[Journal Article] De novo variants in CELF2 that disrupt the nuclear localization signal cause developmental and epileptic encephalopathy2021
- Author(s)
  Itai T, Hamanaka K, Sasaki K, Saitsu H, Miyatake S, Matsumoto N et al.
- Journal Title
  
  Hum Mutat
  
  Volume: 42 Issue: 1 Pages: 66-76
- DOI
  10.1002/humu.24130
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-19K16921, KAKENHI-PROJECT-19K17865
[Journal Article] ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H(+)-ATPases is essential for brain development in humans and mice2021
- Author(s)
  Aoto K, Kato M, Akita T, Nakashima M, Mutoh H, Akasaka N, Tohyama J, Nomura Y, Hoshino K, Ago Y, Tanaka R, Epstein O, Ben-Haim R, Heyman E, Miyazaki T, Belal H, Takabayashi S, Ohba C, Takata A, Mizuguchi T, Miyatake S, Miyake N, Fukuda A, Matsumoto N and Saitsu H
- Journal Title
  
  Nat Commun
  
  Volume: 12 Issue: 1 Pages: 2107-2107
- DOI
  10.1038/s41467-021-22389-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-17H04025, KAKENHI-PROJECT-17K00918, KAKENHI-PROJECT-17K08513, KAKENHI-PROJECT-17K08534, KAKENHI-PROJECT-19H01091, KAKENHI-PUBLICLY-21H05687, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-21H02661, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K07243, KAKENHI-PROJECT-20K07423, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08236
[Journal Article] Complete sequencing of expanded SAMD12 repeats by long-read sequencing with Cas9-mediated enrichment.2021
- Author(s)
  Mizuguchi T, Toyota T, Miyatake S, Mitsuhashi S, Doi H, Kudo Y, Kishida H, Hayashi N, Tusburaya RS, Kinoshita M, Fukuyama T, Fukuda H, Koshimizu E, Tsuchida N, Uchiyama Y, Fujita A, Takata A, Miyake N, Kato M, Tanaka F, Adachi H, Matsumoto N.
- Journal Title
  
  Brain
  
  Volume: 144 Issue: 4 Pages: 1103-1117
- DOI
  10.1093/brain/awab021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-20K08236, KAKENHI-PROJECT-21K07298, KAKENHI-PROJECT-21K15704
[Journal Article] De novo ATP1A3 variants cause polymicrogyria2021
- Author(s)
  Miyatake Satoko、Kato Mitsuhiro、Kumamoto Takuma、Hirose Tomonori、他
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 13 Pages: 2368-2368
- DOI
  10.1126/sciadv.abd2368
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06893, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-18K15677, KAKENHI-PUBLICLY-19H04795, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-19K16921, KAKENHI-PROJECT-19K08281, KAKENHI-PROJECT-20H03438, KAKENHI-ORGANIZER-21H05158, KAKENHI-PLANNED-21H05159, KAKENHI-PROJECT-19H03228, KAKENHI-PROJECT-20H03270, KAKENHI-PROJECT-21H02405, KAKENHI-PROJECT-20K08236, KAKENHI-PROJECT-21K06051, KAKENHI-PROJECT-21K19356, KAKENHI-PROJECT-21K19413
[Journal Article] Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder2021
- Author(s)
  Nishioka Masaki、Kazuno An-a、Nakamura Takumi、Sakai Naomi…Oka Takashi、Matoba Nana、Kataoka Muneko、Alkanaq Ahmed N.、Hamanaka Kohei、Tsuboi Takashi、Sengoku Toru、Ogata Kazuhiro、Iwata Nakao、Ikeda Masashi、Matsumoto Naomichi、Kato Tadafumi、Takata Atsushi
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 3750-3750
- DOI
  10.1038/s41467-021-23453-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-21K07500, KAKENHI-PROJECT-20H03605, KAKENHI-PLANNED-18H05435
[Journal Article] Efficient detection of copy‐number variations using exome data: Batch‐ and sex‐based analyses2020
- Author(s)
  Uchiyama Yuri、Yamaguchi Daisuke、Iwama Kazuhiro, et al.
- Journal Title
  
  Human Mutation
  
  Volume: 42 Issue: 1 Pages: 50-65
- DOI
  10.1002/humu.24129
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08289, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-20K08236, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-19K16921, KAKENHI-PROJECT-19K17865, KAKENHI-PROJECT-18K07865
[Journal Article] Hemizygous FLNA variant in West syndrome without periventricular nodular heterotopia2020
- Author(s)
  Hiromoto Y, Azuma Y, Suzuki Y, Hoshina M, Uchiyama Y, Mitsuhashi S, Miyatake S, Mizuguchi T, Takata A, Miyake N, Kato M, Matsumoto N.
- Journal Title
  
  Hum Genome Var
  
  Volume: 7 Issue: 1 Pages: 43-43
- DOI
  10.1038/s41439-020-00131-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-19K17307, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-19K17865
[Journal Article] The identification of two pathogenic variants in a family with mild and severe forms of developmental delay2020
- Author(s)
  Miyake Noriko、Heydari Shermineh、Garshasbi Masoud、Saitoh Shinji、Nasiri Jafar、Hamanaka Kohei、Takata Atsushi、Matsumoto Naomichi、Beheshti Farnaz Hosseini、Chaleshtori Ahmad Reza Salehi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 66 Issue: 4 Pages: 445-448
- DOI
  10.1038/s10038-020-0809-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-19H03621
[Journal Article] Whole exome sequencing of fetal structural anomalies detected by ultrasonography2020
- Author(s)
  Aoi Hiromi、Mizuguchi Takeshi、Suzuki Toshifumi、Makino Shintaro、Yamamoto Yuka...Takata Atsushi、Miyake Noriko、Takeda Satoru、Itakura Atsuo、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 66 Issue: 5 Pages: 499-507
- DOI
  10.1038/s10038-020-00869-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-19K17865, KAKENHI-PROJECT-20K08164
[Journal Article] Novel EXOSC9 variants cause pontocerebellar hypoplasia type 1D with spinal motor neuronopathy and cerebellar atrophy2020
- Author(s)
  Sakamoto Masamune、Iwama Kazuhiro、Sekiguchi Futoshi、Mashimo Hideaki、Kumada Satoko、Ishigaki Keiko、Okamoto Nobuhiko、Behnam Mahdiyeh、Ghadami Mohsen、Koshimizu Eriko、Miyatake Satoko、Mitsuhashi Satomi、Mizuguchi Takeshi、Takata Atsushi、Saitsu Hirotomo、Miyake Noriko、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 66 Issue: 4 Pages: 401-407
- DOI
  10.1038/s10038-020-00853-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-19K16921, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-20K08164
[Journal Article] 精神神経疾患のレアバリアント研究2020
- Author(s)
  高田篤
- Journal Title
  
  医学のあゆみ
  
  Volume: 272 Pages: 1200-1205
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] RALA mutation in a patient with autism spectrum disorder and Noonan syndrome-like phenotype2019
- Author(s)
  Okamoto Nobuhiko、Takata Atsushi、Miyake Noriko、Matsumoto Naomichi
- Journal Title
  
  Congenital Anomalies
  
  Volume: NA Issue: 6 Pages: 195-196
- DOI
  10.1111/cga.12327
- NAID
  50014240945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] Pathogenic variants of DYNC2H1, KIAA0556, and PTPN11 associated with hypothalamic hamartoma2019
- Author(s)
  Fujita Atsushi、Higashijima Takefumi、Shirozu Hiroshi、Masuda Hiroshi、Sonoda Masaki、Tohyama Jun、Kato Mitsuhiro、Nakashima Mitsuko、Tsurusaki Yoshinori、Mitsuhashi Satomi、Mizuguchi Takeshi、Takata Atsushi、Miyatake Satoko、Miyake Noriko、Fukuda Masafumi、Kameyama Shigeki、Saitsu Hirotomo、Matsumoto Naomichi
- Journal Title
  
  Neurology
  
  Volume: 93 Issue: 3
- DOI
  10.1212/wnl.0000000000007774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-16K09975, KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17K19536
[Journal Article] Recurrent NUS1 canonical splice donor site mutation in two unrelated individuals with epilepsy, myoclonus, ataxia and scoliosis - a case report2019
- Author(s)
  Den Kouhei、Kudo Yosuke、Kato Mitsuhiro、Watanabe Kosuke、Doi Hiroshi、Tanaka Fumiaki、Oguni Hirokazu、Miyatake Satoko、Mizuguchi Takeshi、Takata Atsushi、Miyake Noriko、Mitsuhashi Satomi、Matsumoto Naomichi
- Journal Title
  
  BMC Neurology
  
  Volume: 19 Issue: 1 Pages: 253-253
- DOI
  10.1186/s12883-019-1489-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07503, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-16K09975, KAKENHI-PROJECT-17K10080
[Journal Article] Hemorrhagic stroke and renovascular hypertension with Grange syndrome arising from a novel pathogenic variant in YY1AP12019
- Author(s)
  Saida Ken、Kim Chong Ae、Ceroni Jos? Ricardo Magliocco、Bertola Debora Romeo、Honjo Rachel Sayuri、Mitsuhashi Satomi、Takata Atsushi、Mizuguchi Takeshi、Miyatake Satoko、Miyake Noriko、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 9 Pages: 885-890
- DOI
  10.1038/s10038-019-0626-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K10080
[Journal Article] Haploinsufficiency of A20 caused by a novel nonsense variant or entire deletion of TNFAIP3 is clinically distinct from Beh?et’s disease2019
- Author(s)
  Tsuchida Naomi、Kirino Yohei、Soejima Yutaro、Onodera Masafumi、Arai Katsuhiro、Tamura Eiichiro、Ishikawa Takashi、Kawai Toshinao、Uchiyama Toru、Nomura Shigeru、Kobayashi Daisuke、Taguri Masataka、Mitsuhashi Satomi、Mizuguchi Takeshi、Takata Atsushi、Miyake Noriko、Nakajima Hideaki、Miyatake Satoko、Matsumoto Naomichi
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 21 Issue: 1 Pages: 137-137
- DOI
  10.1186/s13075-019-1928-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-19H03700, KAKENHI-PROJECT-19K08312
[Journal Article] Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice2019
- Author(s)
  Mukai Jun、Cannav? Enrico、Crabtree Gregg W.、Sun Ziyi、Diamantopoulou Anastasia、Thakur Pratibha、Chang Chia-Yuan、Cai Yifei、Lomvardas Stavros、Takata Atsushi、Xu Bin、Gogos Joseph A.
- Journal Title
  
  Neuron
  
  Volume: 104 Issue: 3 Pages: 471-487
- DOI
  10.1016/j.neuron.2019.09.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H03320
[Journal Article] MYRF haploinsufficiency causes 46,XY and 46,XX disorders of sex development: bioinformatics consideration2019
- Author(s)
  Hamanaka K、Takata A、Uchiyama Y、Miyatake S、Miyake N、Mitsuhashi S、Iwama K、Fujita A、Imagawa E、Alkanaq AN、Koshimizu E、Azuma Y、Nakashima M、Mizuguchi T、Saitsu H、Wada Y、Minami S、Katoh-Fukui Y、Masunaga Y、Fukami M、Hasegawa T、Ogata T、Matsumoto N
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 印刷中 Issue: 14 Pages: 2319-2329
- DOI
  10.1093/hmg/ddz066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06926, KAKENHI-PLANNED-17H06428, KAKENHI-PROJECT-17K15630, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-17H04204, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K10080
[Journal Article] A novel homozygous truncating variant of NECAP1 in early infantile epileptic encephalopathy: the second case report of EIEE212019
- Author(s)
  Mizuguchi Takeshi、Nakashima Mitsuko、Moey Lip H.、Ch’ng Gaik S.、Khoo Teik-Beng、Mitsuhashi Satomi、Miyatake Satoko、Takata Atsushi、Miyake Noriko、Saitsu Hirotomo、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 4 Pages: 347-350
- DOI
  10.1038/s10038-018-0556-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17K15630, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254
[Journal Article] Comparison of mitochondrial DNA variants detection using short- and long-read sequencing2019
- Author(s)
  Alkanaq Ahmed N.、Hamanaka Kohei、Sekiguchi Futoshi、Taguri Masataka、Takata Atsushi、Miyake Noriko、Miyatake Satoko、Mizuguchi Takeshi、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 11 Pages: 1107-1116
- DOI
  10.1038/s10038-019-0654-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K10080
[Journal Article] Primary immunodeficiency with chronic enteropathy and developmental delay in a boy arising from a novel homozygous RIPK1 variant2019
- Author(s)
  Uchiyama Yuri、Kim Chong A、Pastorino Antonio Carlos、Ceroni Jos?、Lima Patricia Picciarelli、de Barros Dorna Mayra、Honjo Rachel Sayuri、Bertola D?bora、Hamanaka Kohei、Fujita Atsushi、Mitsuhashi Satomi、Miyatake Satoko、Takata Atsushi、Miyake Noriko、Mizuguchi Takeshi、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 9 Pages: 955-960
- DOI
  10.1038/s10038-019-0631-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K10080
[Journal Article] Comprehensive analysis of coding variants highlights genetic complexity in developmental and epileptic encephalopathy2019
- Author(s)
  Takata Atsushi、Nakashima Mitsuko、Saitsu Hirotomo、Osaka Hitoshi、Nakamura Kazuyuki、Takeshita Saoko、Sakai Yasunari、Miyake Noriko、Miyatake Satoko、Matsumoto Naomichi
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 2506-2506
- DOI
  10.1038/s41467-019-10482-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08281, KAKENHI-PROJECT-19K08289, KAKENHI-PROJECT-19K08322, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-16K09975, KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-18K07865
[Journal Article] A novel de novo frameshift variant in SETD1B causes epilepsy2019
- Author(s)
  Den Kouhei、Kato Mitsuhiro、Yamaguchi Tokito、Miyatake Satoko、Takata Atsushi、Mizuguchi Takeshi、Miyake Noriko、Mitsuhashi Satomi、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 8 Pages: 821-827
- DOI
  10.1038/s10038-019-0617-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K10080
[Journal Article] Novel SUZ12 mutations in Weaver-like syndrome2018
- Author(s)
  Imagawa Eri、Albuquerque Edoarda V.A.、Isidor Bertrand、Mitsuhashi Satomi、Mizuguchi Takeshi、Miyatake Satoko、Takata Atsushi、Miyake Noriko、Boguszewski Margaret C.S.、Boguszewski C?sar L.、Lerario Antonio M.、Funari Mariana A.、Jorge Alexander A.L.、Matsumoto Naomichi
- Journal Title
  
  Clinical Genetics
  
  Volume: 94 Issue: 5 Pages: 461-466
- DOI
  10.1111/cge.13415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K15630
[Journal Article] De novo truncating variants in PHF21A cause intellectual disability and craniofacial anomalies2018
- Author(s)
  Hamanaka Kohei、Sugawara Yuji、Shimoji Takeyoshi、Nordtveit Tone Irene、Kato Mitsuhiro、Nakashima Mitsuko、Saitsu Hirotomo、Suzuki Toshimitsu、Yamakawa Kazuhiro、Aukrust Ingvild、Houge Gunnar、Miyatake Satoko、Matsumoto Naomichi、et al.
- Journal Title
  
  European Journal of Human Genetics
  
  Volume: 27 Issue: 3 Pages: 378-383
- DOI
  10.1038/s41431-018-0289-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17H06994, KAKENHI-PROJECT-17K15630
[Journal Article] PRUNE1-related disorder: Expanding the clinical spectrum2018
- Author(s)
  Imagawa E.、Yamamoto Y.、Mitsuhashi S.、Isidor B.、Fukuyama T.、Kato M.、Sasaki M.、Tanabe S.、Miyatake S.、Mizuguchi T.、Takata A.、Miyake N.、Matsumoto N.
- Journal Title
  
  Clinical Genetics
  
  Volume: 94 Issue: 3-4 Pages: 362-367
- DOI
  10.1111/cge.13385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K15630
[Journal Article] Estimating contribution of rare non-coding variants to neuropsychiatric disorders2018
- Author(s)
  Takata Atsushi
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 73 Issue: 1 Pages: 2-10
- DOI
  10.1111/pcn.12774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] A novel missense SNAP25b mutation in two affected siblings from an Israeli family showing seizures and cerebellar ataxia2018
- Author(s)
  Fukuda Hiroyuki、Imagawa Eri、Hamanaka Kohei、Fujita Atsushi、Mitsuhashi Satomi、Miyatake Satoko、Mizuguchi Takeshi、Takata Atsushi、Miyake Noriko、Kramer Uri、Matsumoto Naomichi、Fattal-Valevski Aviva
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Issue: 5 Pages: 673-676
- DOI
  10.1038/s10038-018-0421-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05357, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K15630
[Journal Article] GRIN2D variants in three cases of developmental and epileptic encephalopathy2018
- Author(s)
  Tsuchida Naomi、Hamada Keisuke、Shiina Masaaki、Kato Mitsuhiro、Kobayashi Yu、Tohyama Jun、Kimura Kazue、Hoshino Kyoko、Ganesan Vigneswari、Teik Keng W.、Nakashima Mitsuko、Mitsuhashi Satomi、Mizuguchi Takeshi、Takata Atsushi、Miyake Noriko、Saitsu Hirotomo、Ogata Kazuhiro、Miyatake Satoko、Matsumoto Naomichi
- Journal Title
  
  Clinical Genetics
  
  Volume: 94 Issue: 6 Pages: 538-547
- DOI
  10.1111/cge.13454
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H03293, KAKENHI-PROJECT-16H05160, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K15630
[Journal Article] Expanding the phenotype of IBA57 mutations: related leukodystrophy can remain asymptomatic2018
- Author(s)
  Hamanaka Kohei、Miyatake Satoko、Zerem Ayelet、Lev Dorit、Blumkin Luba、Yokochi Kenji、Fujita Atsushi、Imagawa Eri、Iwama Kazuhiro、Nakashima Mitsuko、Mitsuhashi Satomi、Mizuguchi Takeshi、Takata Atsushi、Miyake Noriko、Saitsu Hirotomo、van der Knaap Marjo S.、Lerman-Sagie Tally、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Issue: 12 Pages: 1223-1229
- DOI
  10.1038/s10038-018-0516-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17H06994, KAKENHI-PROJECT-17K15630
[Journal Article] Biallelic COLGALT1 variants are associated with cerebral small vessel disease2018
- Author(s)
  Miyatake Satoko、Schneeberger Sacha、Koyama Norihisa、Yokochi Kenji、Ohmura Kayo、、Hennet Thierry、Matsumoto Naomichi、et al
- Journal Title
  
  Annals of Neurology
  
  Volume: 84 Issue: 6 Pages: 843-853
- DOI
  10.1002/ana.25367
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-18K07503, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H03293, KAKENHI-PROJECT-16H05160, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17H06994, KAKENHI-PROJECT-17K15630
[Journal Article] A novel SLC9A1 mutation causes cerebellar ataxia2018
- Author(s)
  Iwama Kazuhiro、Osaka Hitoshi、Ikeda Takahiro、Mitsuhashi Satomi、Miyatake Satoko、Takata Atsushi、Miyake Noriko、Ito Shuichi、Mizuguchi Takeshi、Matsumoto Naomichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Issue: 10 Pages: 1049-1054
- DOI
  10.1038/s10038-018-0488-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K15630
[Journal Article] Recurrent SCN3A p.Ile875Thr variant in patients with polymicrogyria2018
- Author(s)
  Miyatake Satoko、Kato Mitsuhiro、Sawaishi Yukio、Saito Takashi、Nakashima Mitsuko、Mizuguchi Takeshi、Mitsuhashi Satomi、Takata Atsushi、Miyake Noriko、Saitsu Hirotomo、Matsumoto Naomichi
- Journal Title
  
  Annals of Neurology
  
  Volume: 84 Issue: 1 Pages: 159-161
- DOI
  10.1002/ana.25256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K15630
[Journal Article] SOFT syndrome in a patient from Chile2018
- Author(s)
  Saida Ken、Silva Sebastian、Solar Benjamin、Fujita Atsushi、Hamanaka Kohei、Mitsuhashi Satomi、Koshimizu Eriko、Mizuguchi Takeshi、Miyatake Satoko、Takata Atsushi、Miyake Noriko、Matsumoto Naomichi
- Journal Title
  
  American Journal of Medical Genetics Part A
  
  Volume: 179 Issue: 3 Pages: 338-340
- DOI
  10.1002/ajmg.a.61015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17H06994, KAKENHI-PROJECT-17K15630
[Journal Article] Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder2018
- Author(s)
  Takata A, Miyake N, Tsurusaki Y, Fukai R, Miyatake S, Koshimizu E, Kushima I, Okada T, ...Matsumoto N.
- Journal Title
  
  Cell Reports
  
  Volume: 22(3) Issue: 3 Pages: 734-747
- DOI
  10.1016/j.celrep.2017.12.074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10248, KAKENHI-PROJECT-17K19536, KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04889, KAKENHI-PROJECT-16H05160, KAKENHI-PROJECT-16H05357, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17H06747, KAKENHI-PROJECT-16K19626, KAKENHI-PROJECT-18K07893, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-17K15630
[Journal Article] A novel CYCS mutation in the α‐helix of the CYCS C‐terminal domain causes non‐syndromic thrombocytopenia2018
- Author(s)
  Uchiyama Yuri、Yanagisawa Kunio、Kunishima Shinji、Shiina Masaaki、Ogawa Yoshiyuki、Nakashima Mitsuko、Hirato Junko、Imagawa Eri、Fujita Atsushi、Hamanaka Kohei、Miyatake Satoko、Mitsuhashi Satomi、Takata Atsushi、Miyake Noriko、Ogata Kazuhiro、Handa Hiroshi、Matsumoto Naomichi、Mizuguchi Takeshi
- Journal Title
  
  Clinical Genetics
  
  Volume: 94 Issue: 6 Pages: 548-553
- DOI
  10.1111/cge.13423
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-18K07809, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H03293, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17H06994, KAKENHI-PROJECT-17K15630
[Journal Article] Confirmation of SLC5A7-related distal hereditary motor neuropathy 7 in a family outside Wales2018
- Author(s)
  Hamanaka K.、Takahashi K.、Miyatake S.、Mitsuhashi S.、Hamanoue H.、Miyaji Y.、Fukai R.、Doi H.、Fujita A.、Imagawa E.、Iwama K.、Nakashima M.、Mizuguchi T.、Takata A.、Miyake N.、Takeuchi H.、Tanaka F.、Matsumoto N.
- Journal Title
  
  Clinical Genetics
  
  Volume: 94 Issue: 2 Pages: 274-275
- DOI
  10.1111/cge.13369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-18K07503, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254, KAKENHI-PROJECT-17K15630
[Journal Article] 【自閉スペクトラム症(ASD)研究の動向】自閉スペクトラム症のゲノム研究　Exome, whole genome and beyond2017
- Author(s)
  高田篤、松本直通
- Journal Title
  
  分子精神医学
  
  Volume: 17 Pages: 17254-260
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci2017
- Author(s)
  Atsushi Takata, Naomichi Matsumoto & Tadafumi Kato
- Journal Title
  
  Nature Communications
  
  Volume: NA Issue: 1
- DOI
  10.1038/ncomms14519
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] ゲノム研究発展の長期展望2017
- Author(s)
  高田篤, 吉川武男
- Journal Title
  
  精神科
  
  Volume: 30 Pages: 206-212
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] 【精神医学研究の発展可能性に関する長期展望:臨床への還元の視点とともに】ゲノム研究発展の長期展望2017
- Author(s)
  高田篤、吉川武男
- Journal Title
  
  精神科
  
  Volume: 30 Pages: 206-212
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] 【基礎研究で活躍する精神科医の魂はいずこに宿るか?】ゲノム研究でDisorderをDiseaseにする試み2017
- Author(s)
  高田篤
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: 28 Pages: 140-143
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] 統合失調症のエクソーム解析、その現在地2016
- Author(s)
  高田篤
- Journal Title
  
  分子精神医学
  
  Volume: 16 Pages: 167-173
- Data Source
  KAKENHI-PROJECT-16H06254
[Journal Article] 大きな効果をもって統合失調症と関連する遺伝子!?SETD1A2015
- Author(s)
  高田篤
- Journal Title
  
  分子精神医学
  
  Volume: 15 Pages: 227-229
- Data Source
  KAKENHI-PROJECT-15H06867
[Presentation] Where should we go after identifying single genes associated with neuropsychiatric disorders with large effect sizes2023
- Author(s)
  高田篤
- Organizer
  The 2nd RIKEN CBS Co-Creation International Conference
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] 統合失調症のゲノム研究最前線・分かってきたことと、分かっていないこと2023
- Author(s)
  高田篤
- Organizer
  第17回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] 統合オミクス解析による精神神経疾患の病態解明2023
- Author(s)
  高田篤 , 水野翔太, 丹羽優希
- Organizer
  先進ゲノム支援拡大班会議
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] 統合失調症のゲノム研究最前線・分かってきたことと、分かっていないこと2023
- Author(s)
  高田篤
- Organizer
  第17回日本統合失調症学会
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] 大規模ヒト遺伝研究に基づく病因妥当性が高い精神疾患マウスモデルの研究から見えてきたもの2023
- Author(s)
  高田篤
- Organizer
  第166回日本獣医学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] クラスタ/ハブ細胞を決定する遺伝子・鍵分子経路の特定およびヒト疾患との関連解析2023
- Author(s)
  高田篤
- Organizer
  学術変革B領域ハブ決定剛軟因子領域シンポジウム
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] クラスタ/ハブ細胞を決定する遺伝子・鍵分子経路の特定およびヒト疾患との関連解析2023
- Author(s)
  高田篤
- Organizer
  学術変革B領域ハブ決定剛軟因子領域シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] データ駆動型アプローチによるてんかん性脳症のゲノム解析と分子診断精度向上にむけての取り組み2022
- Author(s)
  高田篤
- Organizer
  第64回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] 体細胞変異と精神神経疾患2022
- Author(s)
  高田篤
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] クラスタ/ハブ細胞の遺伝子発現特性解明に向けた一細胞シーケンス解析の取り組み2022
- Author(s)
  高田篤
- Organizer
  次世代脳プロジェクト・冬のシンポジウム
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] クラスタ/ハブ細胞の遺伝子発現特性解明に向けた一細胞シーケンス解析の取り組み2022
- Author(s)
  高田篤
- Organizer
  次世代脳プロジェクト・冬のシンポジウム
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] Investigation of newly arising mutations in psychiatric disorders and their implication in abnormal aging2022
- Author(s)
  高田篤
- Organizer
  RIKEN Aging Project Annual Meeting
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] Investigation of newly arising mutations in psychiatric disorders and their implication in abnormal aging2022
- Author(s)
  高田篤
- Organizer
  RIKEN Aging Project Annual Meeting
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] 5.データ駆動型アプローチによるてんかん性脳症のゲノム解析と分子診断精度向上にむけての取り組み2022
- Author(s)
  高田篤
- Organizer
  第64回日本小児神経学会学術集会
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] クラスタ/ハブ細胞を決定する遺伝子・鍵分子経路の特定およびヒト疾患との関連解析2022
- Author(s)
  高田篤
- Organizer
  学術変革B領域ハブ決定剛軟因子領域シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] 体細胞変異と精神神経疾患2022
- Author(s)
  高田篤
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] クラスタ/ハブ細胞を決定する遺伝子・鍵分子経路の特定およびヒト疾患との関連解析2022
- Author(s)
  高田篤
- Organizer
  学術変革B領域ハブ決定剛軟因子領域シンポジウム
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] 統計学と人工知能で世界標準の遺伝子診断ガイドラインをカイゼンする2021
- Author(s)
  高田篤
- Organizer
  AMEDゲノム医療基盤研究開発課・令和2年度成果報告会
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] The rare variant genetics of neuropsychiatric disorders; exome sequencing and beyond2021
- Author(s)
  高田篤
- Organizer
  The 1st CJK (China-Japan-Korea) International Meeting on Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02855
[Presentation] The rare variant genetics of neuropsychiatric disorders; exome sequencing and beyond2021
- Author(s)
  高田篤
- Organizer
  The 1st CJK (China-Japan-Korea) International Meeting on Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] クラスタ/ハブ細胞を決定する遺伝子・鍵分子経路の特定およびヒト疾患との関連解析2021
- Author(s)
  高田篤
- Organizer
  クラスタ／ハブダイナミズムの決定剛軟因子キックオフシンポジウム
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] 自閉スペクトラム症のゲノム解析2020
- Author(s)
  高田篤
- Organizer
  日本人類遺伝学会第65回大会
- Data Source
  KAKENHI-PLANNED-20H05777
[Presentation] 自閉スペクトラム症（ASD）の遺伝子解析2019
- Author(s)
  高田篤
- Organizer
  生理学若手サマースクール
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] Single-gene diseases among complex neuropsychiatric disorders and genetic complexity in supposed single-gene neurodevelopmental diseases2019
- Author(s)
  高田篤
- Organizer
  PSTC Japan Safety Biomarker Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] ゲノムで変わる!? 精神疾患の診断と治療2019
- Author(s)
  高田篤
- Organizer
  日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] 精神科プレシジョンメディスンとPGx 精神疾患のプレシジョン・メディシン今できること、できないこと、なすべきこと2019
- Author(s)
  高田篤
- Organizer
  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] シン・ゲノム研究でdisorderをdiseaseにする試み2018
- Author(s)
  高田　篤
- Organizer
  第40回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] うつ病以外の精神神経疾患のPrecision Medicineからのヒント2018
- Author(s)
  高田　篤
- Organizer
  28回日本臨床精神神経薬理学会・48回日本神経精神薬理学会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] 精神神経疾患のrare variant解析とその解釈2018
- Author(s)
  高田　篤
- Organizer
  第40回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] 最先端の遺伝研究が解き明かすゲノム因性精神神経発達障害2017
- Author(s)
  高田篤
- Organizer
  第113回　日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] Integrative genetic analysis of neuropsychiatric disorders2017
- Author(s)
  高田篤
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-16H06254
[Presentation] ゲノム研究でdisorderをdiseaseにする試み2016
- Author(s)
  高田篤
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-16H06254

1. 前川素子 (50435731)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 岩本和也 (40342753)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 大西哲生 (80373281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Murayama Masanori (30578901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 竹田晃人 (70397040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 垣内千尋 (90342766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中谷明弘 (60301149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 國井泰人 (00511651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 久保健一郎 (20348791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石田綾 (40424171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 杉浦悠毅 (30590202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 坂内博子 (40332340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANAKA Fumiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. FUJITA atushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. MATSUMOTO Naomichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
16. ADACHI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. KATOH-FUKUI Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. HIROSE Tomonori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 宮武聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
20. 土井宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 水口剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 三宅紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 藤井久彌子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 豊田知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 中村匠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 酒井康成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 岡田俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Takata Atsushi 高田 篤

Research Projects

Research Products

Co-Researchers

Elucidation of Molecular Pathology of Schizophrenia Through Cross-Species Spatial Transcriptomics at Sub-Single-Cell ResolutionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms Linking Maternal Undernutrition to Schizophrenia Risk in Offspring via Metabolic Dysregulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring the Mechanisms of Schizophrenia Induced by Malnutrition During Brain Development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive investigation of rare germline and somatic mutations in bipolar disorder by large-scale sequencing analysis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Morphological features and gene expression patterns underlying hub neurons

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of genes and key molecular pathways determining cluster/hub cells and analysis of their association with human diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of splicing regulation and splicing quantitative trait loci (sQTL) in brains of major psychosesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Target resequencing of SETD1A, a strong candidate gene for schizophrenia with exome-wide significance, using the next generation sequencerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Transcriptomic dysregulation and autistic-like behaviors in Kmt2c haploinsufficient mice rescued by an LSD1 inhibitor2024

Author(s)

Journal Title

DOI

URL

Language

Data Source

[Journal Article] Topologically associating domains define the impact of de novo promoter variants on autism spectrum disorder risk2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of bipolar I disorder with a loss‐of‐function variant of schizophrenia risk gene <scp><i>SETD1A</i></scp>: possible expansion of the relevant clinical spectrum supported by a meta‐analysis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular diagnosis of 405 individuals with autism spectrum disorder2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deep exome sequencing identifies enrichment of deleterious mosaic variants in neurodevelopmental disorder genes and mitochondrial tRNA regions in bipolar disorder2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice2023

Takata Atsushi 高田篤