Numakawa Tadahiro 沼川忠広

… Alternative Names

NUMAKAWA Tadahiro 沼川忠広

Less

Researcher Number	40425690
Other IDs
Affiliation (Current)	2025: 熊本大学, 発生医学研究所, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 熊本大学, 発生医学研究所, 助教 2014 – 2022: 熊本大学, 発生医学研究所, 特定事業研究員 2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第三部, 客員研究員 2013: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第3部, 室長 2010 – 2012: 独立行政法人国立精神・神経医療研究センター, 神経研究所・疾病研究第三部, 室長 … More 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第3部, 室長 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第三部, 室長 2009 – 2010: National Center of Neurology and Psychiatry, 神経研究所疾病研究第三部, 室長 2009: 国立精神・神経センター, 神経研究所・疾病研究第3部, 室長 2007 – 2008: National Center of Neurology and Psychiatry, 神経研究所疾病研究第三部, 室長 2006: 国立精神・神経センター, 疾病研究第三部, 室長 Less
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Neurophysiology / General neuroscience / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology Except Principal Investigator Pediatrics / Basic Section 53050:Dermatology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Psychiatric science
Keywords	Principal Investigator 脳神経疾患 / 神経科学 / iPS細胞 / 細胞・組織 / ライソゾーム病 / 神経細胞 / 神経栄養因子 / 疾患ヒトニューロン / 神経細胞死 / 中枢神経系の異常 … More / 中枢神経系 / 相互作用 / ニューロン / ミクログリア / iPS / オルガノイド / 脳疾患 / 大脳皮質 / エクソソーム / マイクロRNA / 神経伝達 / microRNA / ストレス / GR / グルココルチコイド / BDNF / うつ病 / 神経疾患の病態と治療 / 精神 / 脳神経疫患 / 脳・神経 … More Except Principal Investigator ゴーシェ病 / iPS細胞 / 免疫療法 / グルコシルスフィンゴシン / ライソソーム / ミトコンドリア機能 / オートファジー / 酸化ストレス / ポストシナプス機能 / プレシナプス機能 / 神経型ゴーシェ病 / 遺伝・先天異常学 / GM1ガングリオシドーシス / 治療薬開発 / Gaucher disease / LAMP1 / GlcSph / 神経型ゴーシェー病 / Neural stem cell / ニューロン / ゴーシェー病 / Neuron / IPS細胞 / 神経幹細胞 / ライソーム病 / 先天代謝異常症 / 神経栄養因子 / 薬理学 / 脳神経疾患 / 神経科学 / 遺伝子 Less

ライソゾーム病の神経障害における細胞内カルシウム亢進と興奮毒性の役割Principal Investigator
- Principal Investigator
  
  沼川忠広
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kumamoto University
iPS細胞を用いたメラノーマに対する新規がん免疫療法の開発
- Principal Investigator
  
  梶原隆太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kumamoto University
Role of the interaction between microglia and neuron in the defected neuronal function in the lysosomal storage diseasePrincipal Investigator
- Principal Investigator
  
  NUMAKAWA Tadahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kumamoto University
Development of novel pathological analysis and medicine in neuropathic Gaucher disease.
- Principal Investigator
  
  城戸淳
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kumamoto University
Development of novel medicine using iPS cells derived from Gaucher disease type II patients
- Principal Investigator
  
  Kido Jun
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kumamoto University
Investigation of cellular/molecular pathophysiology of brain disorders using human brain organoids established from iPS cellsPrincipal Investigator
- Principal Investigator
  
  Numakawa Tadahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Kumamoto University
Drug Development for GM1 Gangliosidosis using the patients-derived iPS cells
- Principal Investigator
  
  Kajihara Ryutaro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kumamoto University
Contribution of brain-specific miRs in the neuronal and glial function and possible transmission of miRs between cells.Principal Investigator
- Principal Investigator
  
  NUMAKAWA Tadahiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Center of Neurology and Psychiatry
Analysis on cellular and molecular mechanism behind the depressive behavior by approaching the functional interaction between stress hormone and BDNF.Principal Investigator
- Principal Investigator
  
  Numakawa Tadahiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kumamoto University
  National Center of Neurology and Psychiatry
Mechanism underlying the glucocorticoid-decreased function of neurotrophic factor in depression.Principal Investigator
- Principal Investigator
  
  NUMAKAWA Tadahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center of Neurology and Psychiatry
Role of neurotrophin receptor p75 in psychiatric diseases
- Principal Investigator
  
  KUNUGI Hiroshi
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  National Center of Neurology and Psychiatry
うつ病関連分子p75の一塩基多型に起因した機能変化の細胞、分子生物学的解析。Principal Investigator
- Principal Investigator
  
  沼川忠広
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center of Neurology and Psychiatry

[Book] "Roles of Trk receptors, tyrosine kinase receptors for neurotrophins, in the developing CNS" , CHAPTER 3 in book "Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders"2023
- Author(s)
  Tadahiro Numakawa and Haruki Odaka
- Total Pages
  350
- Publisher
  Academic Press
- ISBN
  9780443186776
- Data Source
  KAKENHI-PROJECT-20K06857
[Book] Factors Affecting Neurodevelopment2021
- Author(s)
  Numakawa, T*　and Odaka, H.
- Total Pages
  750
- Publisher
  ELSEVIER
- ISBN
  9780128179864
- Data Source
  KAKENHI-PROJECT-20K06857
[Book] 神経特異的microRNAと神経伝達Function of brain specific microRNA and neurotransmission2012
- Author(s)
  沼川忠広, 岸宗一郎, 橋戸和夫, 功刀浩
- Total Pages
  4
- Publisher
  学研メディカル秀潤社『細胞工学』
- Data Source
  KAKENHI-PROJECT-21680034
[Book] 神経特異的microRNAと神経伝達Function of brain specific microRNA and neurotransmissionin specific microRNA and neurotransmission細胞工学2012
- Author(s)
  沼川忠広,岸宗一郎,橋戸和夫
- Publisher
  学研メディカル秀潤社
- Data Source
  KAKENHI-PROJECT-21680034
[Book] 相互作用するストレスホルモン(グルココルチコイド)とBDNF機能2010
- Author(s)
  沼川忠広、功刀浩
- Publisher
  社団法人日本生化学会
- Data Source
  KAKENHI-PROJECT-21680034
[Book] 治療抵抗性うつ病に対するドパミン受容体作動薬の有用性に関する検討2010
- Author(s)
  功刀浩、千葉秀一、堀弘明、沼川忠広
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-21680034
[Book] 相互作用するストレスホルモン(グルココルチコイド)とBDNF機能(生化学)2010
- Author(s)
  沼川忠広、功刀浩
- Total Pages
  4
- Publisher
  社団法人日本生化学会
- Data Source
  KAKENHI-PROJECT-21680034
[Book] 治療抵抗性うつ病に対するドパミン受容体作動薬の有用性に関する検討(Depression Frontier)2010
- Author(s)
  功刀浩、千葉秀一、堀弘明、沼川忠広
- Total Pages
  6
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-21680034
[Book] グルココルチコイド受容体およびBDNF受容体の相互作用に制御されるグルタミン酸放出2009
- Author(s)
  沼川忠広
- Publisher
  神経化学会
- Data Source
  KAKENHI-PROJECT-21680034
[Book] グルココルチコイド受容体およびBDNF受容体の相互作用に制御されるグルタミン酸放出.(Glucocorticoid receptor interdction with TrkB promotes BDNF-triggercd glutamate release.)2009
- Author(s)
  沼川忠広
- Total Pages
  7
- Publisher
  日本神経化学会
- Data Source
  KAKENHI-PROJECT-21680034
[Book] 脳由来神経栄養因子(BDNF)の機能を抑制するストレスホルモン2009
- Author(s)
  沼川忠広、功刀浩
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-21680034
[Book] 先進脳・神経科学2006
- Author(s)
  沼川忠広
- Publisher
  培風館
- Data Source
  KAKENHI-PROJECT-18700374
[Journal Article] An Interaction between Brain-Derived Neurotrophic Factor and Stress-Related Glucocorticoids in the Pathophysiology of Alzheimer’s Disease2024
- Author(s)
  Numakawa Tadahiro、Kajihara Ryutaro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 3 Pages: 1596-1596
- DOI
  10.3390/ijms25031596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07772
[Journal Article] Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases2023
- Author(s)
  Numakawa Tadahiro、Kajihara Ryutaro
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 16 Pages: 1247422-1247422
- DOI
  10.3389/fnmol.2023.1247422
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07772
[Journal Article] Enhanced social reward response and anxiety-like behavior with downregulation of nucleus accumbens glucocorticoid receptor in BALB/c mice2023
- Author(s)
  Chiba S, Numakawa T, Murata T, Kawaminami M, Himi T.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 85 Issue: 1 Pages: 30-39
- DOI
  10.1292/jvms.22-0103
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06857, KAKENHI-PROJECT-22K06033
[Journal Article] Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer's Disease.2023
- Author(s)
  Numakawa T, Kajihara R.
- Journal Title
  
  Life (Basel).
  
  Volume: 13 Issue: 3 Pages: 647-647
- DOI
  10.3390/life13030647
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06857
[Journal Article] The Role of Neurotrophin Signaling in Age-Related Cognitive Decline and Cognitive Diseases2022
- Author(s)
  Numakawa Tadahiro、Odaka Haruki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 14 Pages: 7726-7726
- DOI
  10.3390/ijms23147726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15660, KAKENHI-PROJECT-20K06857, KAKENHI-PROJECT-19K16263
[Journal Article] An iPSC-based neural model of sialidosis uncovers glycolytic impairment-causing presynaptic dysfunction and deregulation of Ca2+ dynamics.2021
- Author(s)
  Odaka H, Numakawa T, Soga M, Kido J, Matsumoto S, Kajihara R, Okumiya T, Tani N, Tanoue Y, Fukuda T, Furuya H, Inoue T, Era T.
- Journal Title
  
  Neurobiol Dis.
  
  Volume: 152 Pages: 105279-105279
- DOI
  10.1016/j.nbd.2021.105279
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08207, KAKENHI-PROJECT-20K06857, KAKENHI-PROJECT-19K16263
[Journal Article] Rapid and Simplified Induction of Neural Stem/Progenitor Cells (NSCs/NPCs) and Neurons from Human Induced Pluripotent Stem Cells (hiPSCs).2021
- Author(s)
  Kajihara R, Numakawa T*, Era T.
- Journal Title
  
  Bio Protocol
  
  Volume: 11 Issue: 3
- DOI
  10.21769/bioprotoc.3914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06857
[Journal Article] Brain-Derived Neurotrophic Factor Signaling in the Pathophysiology of Alzheimer's Disease: Beneficial Effects of Flavonoids for Neuroprotection.2021
- Author(s)
  1)Numakawa T, Odaka H.
- Journal Title
  
  International journal of molecular science
  
  Volume: 22 Issue: 11 Pages: 5719-5719
- DOI
  10.3390/ijms22115719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06857, KAKENHI-PROJECT-19K16263
[Journal Article] Novel Drug Candidates Improve Ganglioside Accumulation and Neural Dysfunction in GM1 Gangliosidosis Models with Autophagy Activation2020
- Author(s)
  Ryutaro Kajihara, Tadahiro Numakawa, Haruki Odaka, Yuji Yaginuma, Noemi Fusaki, Toshika Okumiya, Hirokazu Furuya, Seiji Inui, and Takumi Era
- Journal Title
  
  Stem Cell Reports
  
  Volume: 14 Issue: 5 Pages: 1-15
- DOI
  10.1016/j.stemcr.2020.03.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15369, KAKENHI-PROJECT-20K06857, KAKENHI-PROJECT-19K16263, KAKENHI-PROJECT-18K06264
[Journal Article] Actions of Brain-Derived Neurotrophin Factor in the Neurogenesis and Neuronal Function, and Its Involvement in the Pathophysiology of Brain Diseases2018
- Author(s)
  Numakawa Tadahiro、Odaka Haruki、Adachi Naoki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 11 Pages: 3650-3650
- DOI
  10.3390/ijms19113650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07891, KAKENHI-PROJECT-17J04183, KAKENHI-PROJECT-16K06996
[Journal Article] Impact of glucocorticoid on neurogenesis.2017
- Author(s)
  Odaka H., Adachi N. & Numakawa T.
- Journal Title
  
  Neural Regeneration Research
  
  Volume: 12 Issue: 7 Pages: 1028-1035
- DOI
  10.4103/1673-5374.211174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K06996, KAKENHI-PROJECT-17J04183
[Journal Article] Actions of Brain-Derived Neurotrophic Factor and Glucocorticoid Stress in Neurogenesis.2017
- Author(s)
  Numakawa T.*, Odaka H. & Adachi N.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 11 Pages: 2312-2312
- DOI
  10.3390/ijms18112312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K06996, KAKENHI-PROJECT-17J04183
[Journal Article] An in vitro reproduction of stress-induced memory defects: Effects of corticoids on dendritic spine dynamics.2016
- Author(s)
  Saito S, Kimura S, Adachi N, Numakawa T, Ogura A, Tominaga-Yoshino K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 19287-19287
- DOI
  10.1038/srep19287
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300139
[Journal Article] Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity.2014
- Author(s)
  Odaka H, Numakawa T, Adachi N, Ooshima Y, Nakajima S, Katanuma Y, Inoue T, Kunugi H.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 6 Pages: e99271-e99271
- DOI
  10.1371/journal.pone.0099271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300139, KAKENHI-PROJECT-25640019
[Journal Article] Possible protective action of neurotrophic factors and natural compounds against common neurodegenerative diseases.2014
- Author(s)
  Numakawa T.
- Journal Title
  
  Neural Regen Res.
  
  Volume: 9 Issue: 16 Pages: 1506-1508
- DOI
  10.4103/1673-5374.139474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300139, KAKENHI-PROJECT-25640019
[Journal Article] New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases.2014
- Author(s)
  Adachi N, Numakawa T, Richards M, Nakajima S, Kunugi H.
- Journal Title
  
  World J Biol Chem.
  
  Volume: 5 Issue: 4 Pages: 409-428
- DOI
  10.4331/wjbc.v5.i4.409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300139, KAKENHI-PROJECT-25640019
[Journal Article] The Response of Glucocorticoids to Stress and Functional Alteration of Brain-derived Neurotrophic Factor.2013
- Author(s)
  Numakawa T.
- Journal Title
  
  J. Neurol. Transl. Neurosci.
  
  Volume: 1 Pages: 1004-1004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300139
[Journal Article] Neurotrophin BDNF and novel molecular targets in depression pathogenesis.2013
- Author(s)
  Numakawa T., Nakajima S., Adachi N., Richards M. & Kunugi H.
- Journal Title
  
  J. Neurol. Transl. Neurosci.
  
  Volume: 1(3) Pages: 1021-1021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300139
[Journal Article] Neurotrophin BDNF and novel molecular targets in depression pathogenesis.2013
- Author(s)
  Numakawa T, Nakajima S, Adachi N, Richards M, Kunugi H.
- Journal Title
  
  J. Neurol. Transl. Neurosci.
  
  Volume: 1(3) Pages: 1021-1021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640019
[Journal Article] The Response of Glucocorticoids to Stress and Functional Alteration of Brain-derived Neurotrophic Factor.2013
- Author(s)
  Numakawa T.
- Journal Title
  
  J. Neurol. Transl. Neurosci.
  
  Volume: 1 Pages: 1004-1004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640019
[Journal Article] Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex2012
- Author(s)
  Chiba S, Numakawa T, Ninomiya M, Richards MC, Wakabayashi C, Kunugi H.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry.
  
  Volume: 39 Issue: 1 Pages: 112-119
- DOI
  10.1016/j.pnpbp.2012.05.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300139
[Journal Article] 視床下部 -下垂体-副腎系とうつ病 : 最近の展開2012
- Author(s)
  功刀浩、堀弘明、沼川忠広、太田深秀
- Journal Title
  
  日本神経精神薬理学雑誌(Jpn. J. Neuropsychopharmacol.)
  
  Volume: 32 Pages: 203-209
- NAID
  10031055754
- Data Source
  KAKENHI-PROJECT-24300139
[Journal Article] Chronic restraint stress causes anxiety-and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex2012
- Author(s)
  Chiba S, Numakawa T, Ninomiya M, Richards M, Wakabayashi C, Kunugi H
- Journal Title
  
  Progress in Neuro-Psychopharmacology & Biological Psychiatry
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] 神経特異的microRNAと神経伝達2012
- Author(s)
  沼川忠広、岸宗一郎、橋戸和夫、功刀浩
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 683-686
- Data Source
  KAKENHI-PROJECT-24300139
[Journal Article] SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression.2010
- Author(s)
  Tuerxun T, Numakawa T, (他5名)
- Journal Title
  
  Neuroscience Letters 469
  
  Pages: 303-308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] Cyclophosphamide pmmotes the cell survival via activation of intracellular signaling in cultured cortical neucons.2010
- Author(s)
  Kitazawa H,Numakawa T, (他5名)
- Journal Title
  
  Neuroscience Letters 470
  
  Pages: 139-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] Functional interactions between steroid hormones and neurotrophin BDNF.2010
- Author(s)
  Numakawa T, Yokomaku D, Richards M, Hori H, Adachi N, Kunugi H.
- Journal Title
  
  World J.Biol.Chem.
  
  Volume: 1 Pages: 133-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] Functional interactions between steroid hormones and neurotrophin BDNF2010
- Author(s)
  Numakawa T, Yokomaku D, Richards M, Hori H, Adachi N, Kunugi H.
- Journal Title
  
  World J. Biol. Chem
  
  Volume: 1 Issue: 5 Pages: 133-143
- DOI
  10.4331/wjbc.v1.i5.133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression.2010
- Author(s)
  Kunugi H, Hori H, Adachi N, Numakawa T.
- Journal Title
  
  Psychiatry Clin.Neurosci.
  
  Volume: 64 Pages: 447-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upreguladon of glutamate receptors via the suppression of microRNA-132 expression.2010
- Author(s)
  Kawashima H, Numakawa T, (他6名)
- Journal Title
  
  Neuroscience 165
  
  Pages: 1301-1311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] BDNF function and intracellular signaling in neurons2010
- Author(s)
  Numakawa T, Suzuki S, Kumamaru E, Adachi N, Richards M, Kunugi H.
- Journal Title
  
  Histology and Histopathology
  
  Volume: 25 Pages: 237-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] Possible interaction between glucocorticoid and BDNF function2010
- Author(s)
  Numakawa T, Kunugi H.
- Journal Title
  
  生化学
  
  Volume: 82 Pages: 419-422
- NAID
  10026425972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390318
[Journal Article] BDNF function and intracellular signaling in neurons2010
- Author(s)
  Numakawa T, et al
- Journal Title
  
  Histol Histopathol 25
  
  Pages: 237-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390318
[Journal Article] Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression.2010
- Author(s)
  Kunugi H, Hori H, Adachi N, Numakawa T.
- Journal Title
  
  Psychiatry Clin Neurosci. 64(5)
  
  Pages: 447-459
- Data Source
  KAKENHI-PROJECT-20390318
[Journal Article] Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF.2010
- Author(s)
  Ninomiya M, Numakawa T, (他6名)
- Journal Title
  
  Neurosci Lett.
  
  Volume: 476 Pages: 104-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] BDNF function and intracellular signaling in neurons2010
- Author(s)
  Numakawa T, (他5名)
- Journal Title
  
  Histology and Histopathology 25
  
  Pages: 237-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680034
[Journal Article] Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter2009
- Author(s)
  Tadahiro Numakawa, et al.
- Journal Title
  
  Proc Natl Acad Sci USA. 106
  
  Pages: 647-652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390318
[Journal Article] Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter.2009
- Author(s)
  Numakawa T, Kumamaru E, Adachi N, Yagasaki Y, Izumi A, Kunugi H.
- Journal Title
  
  Proc Natl Acad Sci U S A. 106(2)
  
  Pages: 647-652
- Data Source
  KAKENHI-PROJECT-20390318
[Journal Article] 17{beta}-Estradiol Protects Cortical Neurons Against Oxidative Stress-Induced Cell Death through Reduction in the Activity of Mitoger-Activated Protein Kinase and in the Accumulation of Intracellular Calcium.2007
- Author(s)
  Numakawa Y, Matsummoto T, Yokomaku D, Taguchi T, Niki E, Hatanaka H, Kunugi H, Numakawa T
- Journal Title
  
  Endocrinology 148
  
  Pages: 627-637
- Data Source
  KAKENHI-PROJECT-18700374
[Journal Article] Chronic Antidepressants Potentiate via Sigma-1 Receptors the Brain-derived Neurotrophic Factor-induced Signaling for Glutamate Release.2006
- Author(s)
  Yagasaki Y, Numakawa T, Kumamaru E, Hayashi T, Su TP, Kunugi H
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 12941-12949
- Data Source
  KAKENHI-PROJECT-18700374
[Journal Article] Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3 -kinase.2006
- Author(s)
  Numakawa Y, Numakawa T, Matsumoto T, Yagasaki Y, Kumamaru E, Kunugi H, Taguchi T, Niki E
- Journal Title
  
  J Neurochem. 97
  
  Pages: 1191-1202
- Data Source
  KAKENHI-PROJECT-18700374
[Journal Article] Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology, and ERK signaling.2006
- Author(s)
  Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, Mori T, Nemoto K, Adachi N, Izumi A, Chiba S, Noguchi H, Suzuki T, Iwata N, Ozaki N, Taguchi T, Kamiya A, Kosuga A, Tatsumi M, Kamijima K, Weinberger DR, Sawa A, Kunugi H
- Journal Title
  
  Hum Mol Genet. 15
  
  Pages: 3024-3033
- Data Source
  KAKENHI-PROJECT-18700374
[Presentation] Dysregulation of neurotransmission in human neurons derived from lysosomal storage disease iPSCs.2022
- Author(s)
  Tadahiro Numakawa
- Organizer
  The 37th International Kumamoto Medical Bioscience Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06857
[Presentation] Development of drug screening system using neural stem cells derived from a patient with Type II Gaucher Disease.2019
- Author(s)
  Jun Kido, Tadahiro Numakawa, Shirou Matsumoto, Haruki Odaka, Minami Soga, Ryutarou Kajihara, Fumio Endo, Kimitoshi Nakamura, Takumi Era.
- Organizer
  SSIEM annual symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10054
[Presentation] SIALIDOSIS NEURONS FROM PATIENT-DERIVED INDUCED PLURIPOTENT STEM CELL EXHIBIT SYNAPTIC DYSFUNCTION2018
- Author(s)
  Haruki Odaka, Tadahiro Numakawa, Minami Soga, Jun Kido, Ryutaro Kajihara, Toshika Okumiya, Hirokazu Furuya, Takafumi Inoue, Takumi Era
- Organizer
  ISSCR 2018 - The International Society of Stem Cell Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K06996
[Presentation] シアリドーシス患者iPS 細胞を用いた神経障害の病理学的解析2017
- Author(s)
  小髙陽樹、沼川忠広、曽我美南、城戸淳、梶原隆太郎、奥宮敏可、古谷博和、井上貴文、江良択実
- Organizer
  第59回日本先天性代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-16K06996
[Presentation] Development of drug screening system using iPS cells derived from a patient with Gaucher Disease Type II2017
- Author(s)
  Jun Kido, Tadahiro Numakawa, Shirou Matsumoto, Hiroki Odaka,　Minami Soga,　Ryutarou Kajihara, Fumio Endo, Kimitoshi Nakamura,Takumi Era.
- Organizer
  The 59th Annual Meeting of the Japanese Society for Inherited Metabolic Diseases
- Data Source
  KAKENHI-PROJECT-17K10054
[Presentation] ゴーシェー病II 型患者由来のiPS 細胞を使用した薬剤スクリーニングシステムの開発2017
- Author(s)
  城戸淳、沼川忠広、松本志郎、小高陽樹、曽我美南、梶原隆太郎、遠藤文夫、中村公俊、江良択実
- Organizer
  第59回日本先天性代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-16K06996
[Presentation] Teneurin-4 Positively Regulates Neural Cell Process Formation and Synaptogenesis2013
- Author(s)
  Nobuharu Suzuki, Tadahiro Numakawa, Joshua Chou, Susana de Vega, Chihiro Mizuniwa, Kaori Sekimoto, Naoki Adachi, Hiroshi Kunugi, Eri Arikawa-Hirasawa, Yoshihiko Yamada, and Chihiro Akazawa
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Possible involvement of shp2 in an influence of glucocorticoid on neurotrophin-dependent synapse regulation2013
- Author(s)
  Tadahiro Numakawa, Naoki Adachi, Emi Kumamaru, Yoshiko Ooshima, and Hiroshi Kunugi
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] The Effect of Phencyclidine on BDNF mRNA Expression in Rat Cultured Cortical Neurons.2013
- Author(s)
  Yusuke Katanuma, Tadahiro Numakawa, Naoki Adachi, Takafumi Inoue, Hiroshi Kunugi
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Aldosterone enhanced release of neurotransmitter in cultured neurons2013
- Author(s)
  Akari Okamoto, Tadahiro Numakawa., Naoki Adachi, Yoshinori Masuo, Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Mineralocorticoid receptorを介した神経機能制御のメカニズム解析2013
- Author(s)
  岡本明理, 沼川忠広, 安達直樹, 増尾良則, 功刀浩
- Organizer
  包括的神経グリア研究会
- Place of Presentation
  浜松市舘山寺サゴーロイヤルホテル(静岡県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 神経障害におけるストレスおよび栄養因子BDNFの役割について2013
- Author(s)
  沼川忠広
- Organizer
  大阪大学　蛋白質研究所　蛋白研リトリート講演
- Place of Presentation
  兵庫県淡路島　夢舞台
- Invited
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Protective effect of cabergoline, a dopamine D2 receptor agonist, on cultured neurons.2013
- Author(s)
  Haruki Odaka, Tadahiro Numakawa, Naoki Adachi, Yoshiko Ooshima, Takafumi Inoue, and Horoshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Glucocorticoids affect the intracellular transport of BDNF in cortical neurons2013
- Author(s)
  Naoki Adachi, Tadahiro Numakawa, Yoshiko Ooshima, Hiroshi Kunugi
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] フェンサイクリジンのBDNF mRNA発現に対する作用解析2013
- Author(s)
  片沼佑介, 沼川忠広, 安達直樹, 井上貴文,功刀浩
- Organizer
  包括的神経グリア研究会
- Place of Presentation
  浜松市舘山寺サゴーロイヤルホテル(静岡県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Aldosterone enhanced release of neurotransmitter in cultured neurons2013
- Author(s)
  Akari Okamoto, Tadahiro Numakawa., Naoki Adachi, Yoshinori Masuo, Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Possible involvement of shp2 in an influence of glucocorticoid on neurotrophin-dependent synapse regulation2013
- Author(s)
  Tadahiro Numakawa, Naoki Adachi, Emi Kumamaru, Yoshiko Ooshima, and Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Teneurin-4 Positively Regulates Neural Cell Process Formation and Synaptogenesis2013
- Author(s)
  Nobuharu Suzuki, Tadahiro Numakawa, Joshua Chou, Susana de Vega, Chihiro Mizuniwa, Kaori Sekimoto, Naoki Adachi, Hiroshi Kunugi, Eri Arikawa-Hirasawa, Yoshihiko Yamada, and Chihiro Akazawa.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Possible change in neurotrophin function in decreased weight rats model.2013
- Author(s)
  Yoshiko Ooshima, Tadahiro Numakawa, Naoki Adachi, and Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] 神経機能をコントロールする神経栄養因子とストレスホルモン2013
- Author(s)
  沼川忠広
- Organizer
  包括的神経グリア研究会
- Place of Presentation
  浜松市舘山寺サゴーロイヤルホテル(静岡県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 大脳皮質ニューロンにおけるGLP-1とBDNFとの相互作用2013
- Author(s)
  中島進吾、沼川忠広、安達直樹、功刀浩
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Glucocorticoids affect the intracellular transport of BDNF in cortical neurons2013
- Author(s)
  Naoki Adachi, Tadahiro Numakawa, Yoshiko Ooshima, Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] 神経障害におけるストレスおよび栄養因子BDNFの役割について2013
- Author(s)
  沼川忠広
- Organizer
  大阪大学　蛋白質研究所　蛋白研リトリート講演
- Place of Presentation
  兵庫県淡路島　夢舞台
- Invited
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 酸化ストレスに対するカベルゴリンの神経保護作用2013
- Author(s)
  小高陽樹, 沼川忠広, 安達直樹, 大島淑子, 井上貴文, 功刀浩
- Organizer
  包括的神経グリア研究会
- Place of Presentation
  浜松市舘山寺サゴーロイヤルホテル(静岡県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Fibroblast growth factor-dependent upregulation of microRNAs in cultured neuronal and glial cells.2013
- Author(s)
  Noriko Yamamoto, Tadahiro Numakawa, Yoshiko Ooshima, Soichiro Kishi, Kazuo Hashido, Naoki Adachi, and Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Stress regulation of glucocorticoids and role of neurotrophic factor in neurons: Implications for depression2013
- Author(s)
  Tadahiro Numakawa
- Organizer
  11th World Congress of Biological Psychiatry
- Place of Presentation
  Kyoto, Japan, Kyoto International Conference Center
- Invited
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] The Effect of Phencyclidine on BDNF mRNA Expression in Rat Cultured Cortical Neurons.2013
- Author(s)
  Yusuke Katanuma, Tadahiro Numakawa, Naoki Adachi, Takafumi Inoue, Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Fibroblast growth factor-dependent upregulation of microRNAs in cultured neuronal and glial cells.2013
- Author(s)
  Noriko Yamamoto, Tadahiro Numakawa, Yoshiko Ooshima, Soichiro Kishi, Kazuo Hashido, Naoki Adachi, and Hiroshi Kunugi.
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] ストレスで変化する神経栄養因子作用のin vitro解析2013
- Author(s)
  沼川忠広
- Organizer
  早稲田大学理工学術院先進理工学部生命医科学科
- Place of Presentation
  早稲田大学先端生命医科学研究センター(東京都)(招待講演)
- Year and Date
  2013-01-15
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Possible change in neurotrophin function in decreased weight rats model.2013
- Author(s)
  Yoshiko Ooshima, Tadahiro Numakawa, Naoki Adachi, and Hiroshi Kunugi
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Stress regulation of glucocorticoids and role of neurotrophic factor in neurons: Implications for depression2013
- Author(s)
  Tadahiro Numakawa
- Organizer
  11th World Congress of Biological Psychiatry
- Place of Presentation
  Kyoto, Japan, Kyoto International Conference Center
- Invited
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 大脳皮質ニューロンにおけるGLP-1とBDNFとの相互作用2013
- Author(s)
  中島進吾、沼川忠広、安達直樹、功刀浩
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Protective effect of cabergoline, a dopamine D2 receptor agonist, on cultured neurons.2013
- Author(s)
  Haruki Odaka, Tadahiro Numakawa, Naoki Adachi, Yoshiko Ooshima, Takafumi Inoue, and Horoshi Kunugi
- Organizer
  Neuro2013
- Place of Presentation
  京都府　京都市　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Behavioral phenotype observed in IL-1Ra KO after chronic mild immobilization stress2012
- Author(s)
  Wakabayashi C, Numakawa T, Kiyama Y, Manabe T, Kunugi H, Iwakura Y
- Organizer
  The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Possible Involvement of miRNA-132 in Neuronal Function of Brain-derived Neurotrophic Factor2012
- Author(s)
  Kishi S, Numakawa T, Adachi N, Kunugi H, Hashido K.
- Organizer
  BIT's 5th Anniversary of PepCon-2012
- Place of Presentation
  Beijing International Conve-ntion Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] MicroRNA-132 induction following bFGF stimulation in glial and neural cultures2012
- Author(s)
  Yamamoto N, Numakawa T, Chiba S, Richards M, Ooshima Y, Kishi S, Hashido K, Adachi N, and Kunugi H
- Organizer
  The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Suppressed release of BDNF contributes to the phencyclidine-caused loss of synapses2012
- Author(s)
  Adachi N, Numakawa T, Kumamaru E, Itami C, Chiba S, Iijima Y, Richards M, R. Katoh-Semba R, Kunugi H
- Organizer
  The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 神経栄養因子とストレスホルモンの相互作用における細胞・分子生物学的解析2012
- Author(s)
  沼川忠広(Tadahiro Numakawa)
- Organizer
  武蔵野大学
- Place of Presentation
  東京都武蔵野市武蔵野大学8号館(招待講演)
- Year and Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Negative Effect of Glucocorticoids on Neuronal Function of Brain-derived Neurotrophic Factor2012
- Author(s)
  Numakawa T, 他5名
- Organizer
  BIT's 5th Anniversary of PepCon-2012
- Place of Presentation
  Beijing International Convention Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Possible Involvement of miRNA-132 in Neuronal Function of Brain-derived Neurotrophic Factor2012
- Author(s)
  Kishi S, Numakawa T, Adachi N, Kunugi H, Hashido K
- Organizer
  BIT's 5th Anniversary of PepCon-2012
- Place of Presentation
  Beijing International Convention Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Targeted molecule of brain-specific microRNA-1322012
- Author(s)
  Kishi S, Numakawa T, Mizuno H, Adachi N, Kunugi H, Hashido K
- Organizer
  The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Phencyclidine-Induced Synaptic Loss via Inhibition of BDNF Secretion in Cultured Cortical Neurons2012
- Author(s)
  Adachi N, Numakawa T, 他7名
- Organizer
  BIT's 5th Anniversary of PepCon-2012
- Place of Presentation
  Beijing International Conve-ntion Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] 細胞・分子生物学的アプローチにより明らかにするストレスホルモンと神経栄養因子の関係2012
- Author(s)
  沼川忠広
- Organizer
  第20回marianna research council(mrc)
- Place of Presentation
  聖マリアンナ医科大学(神奈川県)(招待講演)
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Possible mechanism underlying negative influence of glucocorticoids on BDNF-mediated neuronal function2012
- Author(s)
  Numakawa T, Adachi N, Chiba S, Kumamaru E, Ooshima Y, Hashido K, and Kunugi H
- Organizer
  The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 神経機能を変化させる神経栄養因子/ストレスの分子生物学的解析2012
- Author(s)
  沼川忠広(Tadahiro Numakawa)
- Organizer
  東邦大学
- Place of Presentation
  千葉県船橋市東邦大学理学部第V号館(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Negative Effect of Glucocorticoids on Neuronal Function of Brain-derived Neurotrophic Factor2012
- Author(s)
  Numakawa T, 他5名
- Organizer
  Neurotrophic Factor. BIT's 5th Anniversary of PepCon-2012
- Place of Presentation
  Beijing International Conve-ntion Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Brain derived neurotrophic factor as a key molecule in schizophrenia and mood disorders2012
- Author(s)
  Hiroshi Kunugi, Tadahiro Numakawa, Naoki Adachi, Takashi Fujii.
- Organizer
  第34回日本生物学的精神医学会
- Place of Presentation
  神戸国際会議場(兵庫県)(招待講演)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Basic research on mental disorders and stress-related hormones2012
- Author(s)
  Tadahiro Numakawa.
- Organizer
  Joint Symposium MPI of Psychiatry and NCNP
- Place of Presentation
  Max Planck Institute, Munich, Germany(招待講演)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Intrauterine growth retardation neurons show a reduction in BDNF-mediated neuronal function2012
- Author(s)
  Ooshima Y, Numakawa T, Chiba S, Furuta M, Adachi N, Kunugi H
- Organizer
  The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Phencyclidine-Induced Synaptic Loss via Inhibition of BDNF Secretion in Cultured Cortical Neurons2012
- Author(s)
  Adachi N, Numakawa T, 他7名
- Organizer
  BIT's 5th Anniversary of PepCon-2012
- Place of Presentation
  Beijing International Convention Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Possible involvement of brain-derived neurotrophic factor(BDNF) dysfunction in synaptic loss caused by phencyclidine2011
- Author(s)
  Adachi N, Numakawa T, 他6名
- Organizer
  BIT Life Sciences 4th Annual Protein and Peptide Conference
- Place of Presentation
  Beijing, China National Convention Center
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] BDNF依存的miR-132の発現増加へのグルココルチコイドの抑制的作用2011
- Author(s)
  岸宗一郎、沼川忠広, 他4名
- Organizer
  第30回躁うつ病の薬理・生化学的研究懇話会
- Place of Presentation
  京都府京都市京都ガーデンパレス
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Phencyclidine-induced Synapse Loss through Impairment of BDNF Functi on in Cortical Neurons2011
- Author(s)
  Adachi N, Numakawa T, 他7名
- Organizer
  第32回内藤コンファレンス(Biological Basis of Mental Functions and Disorders)こころの機能と疾患の分子機構
- Place of Presentation
  山梨県北杜市(八ヶ岳ロイヤルホテル)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Interactions between Brain-derived neurotrophic factor and glucocorticoids2011
- Author(s)
  Numakawa T, Adachi N, Kumamaru E, Kunugi H.
- Organizer
  BIT Life Sciences 4th Annual Protein and Peptide Conference
- Place of Presentation
  Beijing, China National Convention Center
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Possible involvement of dysfunction in BDNF function following phencyclidine exposure2011
- Author(s)
  Adachi N, Numakawa T, 他7名
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川県横浜市(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Crosstalk between neurotrophin BDNF and hypothalamic-pituitary-adrenal (HPA) axis.神経栄養因子BDNFとHPA系のクロストーク2011
- Author(s)
  沼川忠広(Tadahiro Numakawa), 安達直樹(Naoki Adachi), 功刀浩(Hiroshi Kunugi)
- Organizer
  第54回日本神経化学会:日本神経化学会・日本生物学的精神医学会合同シンポジウム
- Place of Presentation
  石川県加賀市山代温泉瑠璃光(招待講演)
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Preventive effect by growth factors in suppression in neurotransmitter release after chronic glucocorticoid2011
- Author(s)
  Numakawa T, 他5名
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Possible involvement of brain-derived neurotrophic factor (BDNF) dysfunction in synaptic loss caused by phencyclidine.2011
- Author(s)
  Adachi N, Numakawa T., (他6名)
- Organizer
  BIT Life Sciences' 4th Annual Protein and Peptide Conference
- Place of Presentation
  Beijing, China National Convention Center
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Brain-specific microRNA-132 induction by growth factors in cortical neurons2011
- Author(s)
  Yamamoto N, Numakawa T, 他5名
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川県横浜市(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] BDNF- and estrogen receptor α-mediated intracellular signaling in anxiety- and depression-like behaviors in postpartum rats2011
- Author(s)
  Furuta M, Numakawa T, 他7名
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Interactions between Brain-derived neurotrophic factor and glucocorticoids.2011
- Author(s)
  Numakawa T, Adachi N, Kumamaru E, Kunugi H.
- Organizer
  BIT Life Sciences' 4th Annual Protein and Peptide Conference
- Place of Presentation
  Beijing, China National Convention Center
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Alteration by chronic restraint stress in anxiety- and depression-like behaviors, glucocorticoid receptor expression and BDNF-dependent neuronal function2011
- Author(s)
  Chiba S, Numakawa T, 他5名
- Organizer
  第32回内藤コンファレンス(Biological Basis of Mental Functions and Disorders)こころの機能と疾患の分子機構
- Place of Presentation
  山梨県北杜市(八ヶ岳ロイヤルホテル)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Estrogen receptorα-and BDNF-mediated intracellular signaling in anxiety-and depression-like behaviors in postpartum rats2011
- Author(s)
  Furuta M, Numakawa T, 他6名
- Organizer
  Society for Neuroscience 2011
- Place of Presentation
  Walter E. Washington Convention Center. Washinton D. C., USA
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Interaction between miRNA-132 function and ERK signalings in BDNF-mediated synaptic function2011
- Author(s)
  Kishi S, Numakawa T, 他4名
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Hypothalamic-pituitary-adrenal axis and depression : recent findings.視床下部-下垂体-副腎系とうつ病:最近の知見2011
- Author(s)
  功刀浩(Hiroshi Kunugi), 堀弘明(Hiroaki Hori), 沼川忠広(Tadahiro Numakawa)
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京都新宿区京王プラザホテル(招待講演)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Behavioral and molecular evidence for psychotropic effects in 1-theanine. L-theanineの統合失調症治療に対する有用性の検討2011
- Author(s)
  若林千里, 沼川忠広, 二宮碧, 千葉秀一, 功刀浩
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Changes in emotional behaviors and the action of brain-derived neurotrophic factor in the prefrontal cortex after exposure to chronic restraint stress2011
- Author(s)
  Chiba S, Numakawa T, 他5名
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川県加賀市山代温泉瑠璃光
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Estrogen receptor α- and BDNF-mediated intracellular signaling in anxiety- and depression-like behaviors in postpartum rats2011
- Author(s)
  Furuta M, Numakawa T, 他6名
- Organizer
  Society for Neuroscience 2011
- Place of Presentation
  Walter E. Washington Convention Center. Washinton D.C., USA
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Reduction in BDNF-induced neurotransmitter release in cultured cortical neurons from intrauterine growth retardation rats2011
- Author(s)
  Oshima Y, Numakawa T, 他4名
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Suppression of BDNF secretion contributes to the phencyclidine-induced synaptic dysfunction2011
- Author(s)
  Adachi N, Numakawa T, 他7名
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川県加賀市山代温泉瑠璃光
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Antidepressant- and Anxiolytic-like Properties of Dopamine Receptor Agonist Cabergoline2010
- Author(s)
  Chiba S, Numakawa T, Ninomiya M, Kunugi H.
- Organizer
  Neuro 2010(第33回日本神経科学大会.第53回日本神経化学会大会.第20回日本神経回路学会大会)
- Place of Presentation
  兵庫県神戸市神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Phencyclidine decreases excitatory synaptic sites through suppression of BDNF secretion in cortical neurons2010
- Author(s)
  安達直樹、沼川忠広、熊丸絵美、伊丹千晶、仙波りつ子、功刀浩
- Organizer
  Neuro2010(第33回日本神経科学大会.第53回日本神経化学会大会.第20回日本神経回路学会大会)
- Place of Presentation
  兵庫県神戸市神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Cultured neurons from intrauterine growth retardation rats display lower response to brain-derived neurotrophic factors.2010
- Author(s)
  Ninomiya M, Numakawa T., (他6名)
- Organizer
  Neuro2010(第33回日本神経科学大会.第53回日本神経化学会大会.第20回日本神経回路学会大会)
- Place of Presentation
  兵庫県神戸市神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] GLUCOCORTICOID SUPPRESSES BDNF-TRIGGERED GLUTAMATE RELEASE VIA DECREASING INTERACTION BETWEEN GLUCOCORTICOID RECEPTOR AND TRKB2010
- Author(s)
  Numakawa, T., 他5名
- Organizer
  The Asian-Pacific Society for Neurochemistry
- Place of Presentation
  Phuket Island, Thailand, Phuket Graceland Resort and Spa
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Possible changes in neurotrophin signalings and levels of ERα are involved in anxiety- and depressive-like behaviors in postpartum rats after weaning.2010
- Author(s)
  Furuta M, Numakawa T., (他7名)
- Organizer
  Neuro2010(第33回日本神経科学大会.第53回日本神経化学会大会.第20回日本神経回路学会大会)
- Place of Presentation
  兵庫県神戸市神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] bFGF reversed a suppression in BDNF-stimulated glutamate release caused by glucocorticoid exposure2010
- Author(s)
  Numakawa T, Adachi N, Kumamaru E, Kunugi H
- Organizer
  Neuro2010(第33回日本神経科学大会.第53回日本神経化学会大会.第20回日本神経回路学会大会)
- Place of Presentation
  兵庫県神戸市神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] PHENCYCLIDINE DECREASES EXCITATORY SYNAPSES : POSSIBLE INVOLVEMENT OF DYSFUNCTION OF BRAIN-DERIVED NEUROTROPHIC FACTOR2010
- Author(s)
  Adachi, N., Numakawa, T., 他6名
- Organizer
  The Asian-Pacific Society for Neurochemistry
- Place of Presentation
  Phuket Island, Thailand, Phuket Graceland Resort and Spa
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] Glucocorticoid prevents BDNF-dependent up-regulation of glutamate receptors via the suppression of microRNA miR-132 expression.2009
- Author(s)
  H Kawashima, T Numakawa, (他6名)
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] 幼若期ニューロンヘのグルココルチコイド暴露はBDNFで増強されるシナプス成熟を抑制する2009
- Author(s)
  熊丸絵美、沼川忠広, (他3名)
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  群馬県渋川市(ホテル天坊)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] グルココルチコイド受容体およびBDNF受容体の相互作用に制御されるBDNF依存的グルタミン酸放出2009
- Author(s)
  沼川忠広
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  伊香保温泉ホテル
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-20390318
[Presentation] グルココルチコイド受容体およびBDNF受容体の相互作用に制御されるBDNF依存的グルタミン酸放出2009
- Author(s)
  沼川忠広, (他5名)
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  群馬県渋川市(ホテル天坊)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] グルココルチコイド受容体およびBDNF受容体の相互作用に制御されるグルタミン酸放出.(若手奨励賞シンポジウム)2009
- Author(s)
  沼川忠広
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  群馬県渋川市(ホテル天坊)
- Data Source
  KAKENHI-PROJECT-21680034
[Presentation] 気分障害におけるグルココルチコイドと脳由来神経栄養因子2007
- Author(s)
  功刀浩、沼川忠広
- Organizer
  Neuro2007:第30回日本神経科学大会、第50回日本神経化学会大会、第17回肩本神経回路学会大会合同学会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)'
- Data Source
  KAKENHI-PROJECT-18700374
[Presentation] Inhibitoly effect of glucocorticoid oll BDNF-lnediated maturation of synaptic fimc Lion in developing luppocampal neurons2007
- Author(s)
  熊丸絵美, 沼川忠広(他2名)
- Organizer
  第26回躁うつ病の薬理・生化学的研究懇話会
- Place of Presentation
  広島
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-18700374
[Presentation] グルココルチコイド暴露によるBDNF誘導グルタミン酸放出抑制のメカニズム2007
- Author(s)
  沼川忠広(他5名)
- Organizer
  Neuro2007:第30回日本神経科学大会、第50回日本神経化学会大会、第17回日本神経回路学会大会合同学会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-18700374
[Presentation] フェンサイクリジンによる培養大脳皮質ニューロンからの急速なグルタミン酸放出の増加とBDNF発現上昇2007
- Author(s)
  安達直樹, 沼川忠広(他3名)
- Organizer
  Neuro2007:第30回目本神経科学大会、第50回日本神経化学会大会、第17回日本神経回路学会大会合同学会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-18700374
[Presentation] Glucocorticoid reduced the BDNF-mediated synaptic ma加ration in developing hippocampal neurons2007
- Author(s)
  熊丸絵美, 沼川忠広(他4名)
- Organizer
  Neuro2007:第30回日本神経科学大会、第50回日本神経化学会大会、第17回日本神経回路学会大会合同学会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-18700374
[Presentation] Gyclophosphamideによる培養大脳皮質ニューロンの細胞死抑制効果2007
- Author(s)
  北澤裕美, 沼川忠広(他6名)
- Organizer
  Neuro2007:第30回日本神経科学大会、第50回日本神経化学会大会、第17回日本神経回路学会大会合同学会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-18700374
[Presentation] The mechanisms behind deficits in BDNF function after phencyclidine exposure
- Author(s)
  Adachi N, Numakawa T, Kumamaru E, Itami C, Chiba S, Iijima Y, Richards M, Katoh-Semba R, Kunugi H.
- Organizer
  CSHA/NGF2014 Joint Conference on Nerve Growth Factor and Related Neurotrophic Factors: Emerging Concepts, New Mechanism, Novel Technologies
- Place of Presentation
  Suzhou, PR China
- Year and Date
  2014-06-23 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] High fat diet-induced deficiency of prepulse inhibition in mice
- Author(s)
  Wakabayashi C， Numakawa T， Ooshima Y， Hattori K， Kunugi H.
- Organizer
  第37回日本神経科学大会 Neuroscience 2014.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] 培養大脳皮質ニューロンに対するカベルゴリン（ドーパミンD2受容体アゴニスト）の神経保護効果の解析
- Author(s)
  小髙陽樹、沼川忠広、安達直樹、大島淑子、中島進吾、片沼佑介、井上貴文、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Possible of CD63 in synaptic function of rat cortical neurons.
- Author(s)
  吉村文, 沼川忠広, 中島進吾, 安達直樹, 川又理樹, 落谷孝広, 功刀浩, 玉井淑貴
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] High fat diet-induced deficiency of prepulse inhibition in mice
- Author(s)
  Wakabayashi C， Numakawa T， Ooshima Y， Hattori K， Kunugi H.
- Organizer
  第37回日本神経科学大会 Neuroscience 2014.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Influence of chronic glucocorticoid exposure on proliferation and differentiation of rat neural stem cells in vitro
- Author(s)
  Odaka H, Numakawa T, Yoshimura A, Adachi N, Nakajima S, Era T, Inoue T, Kunugi H.
- Organizer
  熊本医学・生物科学国際シンポジウム
- Place of Presentation
  熊本市医師会館（熊本県）
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] フェンサイクリジン短期曝露は大脳皮質ニューロンのBDNF mRNA発現を急速に低下させる
- Author(s)
  片沼佑介、沼川忠広、安達直樹、山本宣子、大島淑子、小高陽樹、井上貴文、功刀浩
- Organizer
  第37回日本神経科学大会 Neuroscience 2014.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] The effect of IL-6 on expression of microRNAs in rat embryonic neural stem cells during their differentiation.
- Author(s)
  Yoshimura A, Numakawa T, Odaka H, Tamai Y, Era T,
- Organizer
  熊本医学・生物科学国際シンポジウム
- Place of Presentation
  熊本市医師会館（熊本県）
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Glial miR expression following basic fibroblast growth factor application in astrocytes
- Author(s)
  Yamamoto N， Numakawa T， Nakajima S, Ooshima Y, Odaka H， Hashido K， Adachi N， Kunugi H.
- Organizer
  第37回日本神経科学大会 Neuroscience 2014.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] The effect of IL-6 on expression of microRNAs in rat embryonic neural stem cells during their differentiation.
- Author(s)
  Yoshimura A, Numakawa T, Odaka H, Tamai Y, Era T,
- Organizer
  熊本医学・生物科学国際シンポジウム
- Place of Presentation
  熊本市医師会館（熊本県）
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Glucocorticoid stress, neurotrophin, and pathogenesis of psychiatric disorders
- Author(s)
  Tadahiro Numakawa
- Organizer
  熊本大学リエゾンラボ研究会／リーディングプログラム：HIGO最先端研究セミナー
- Place of Presentation
  熊本大学
- Invited
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Decreased release of neurotransmitter induced by BDNF in cultured cortical neurons from IUGR(intrauterine growth retardation) rats
- Author(s)
  Ooshima Y， Numakawa T， Matsumoto T， Chiba S， Furuta M，Izumi A， Ninomiya-Baba M， Odaka H， Hashido K， Adachi N， Kunugi H.
- Organizer
  第37回日本神経科学大会 Neuroscience 2014.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] アストログリア細胞においてbFGF投与で増加したマイクロRNAの機能的役割
- Author(s)
  沼川忠広、中島進吾、山本宣子、大島淑子、小高陽樹、橋戸和夫、安達直樹、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 経口グルコース負荷後のERKの変化
- Author(s)
  中島進吾、沼川忠広、安達直樹、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 経口グルコース負荷後のERKの変化
- Author(s)
  中島進吾、沼川忠広、安達直樹、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] フェンサイクリジン短期曝露は大脳皮質ニューロンのBDNF mRNA発現を急速に低下させる
- Author(s)
  片沼佑介、沼川忠広、安達直樹、山本宣子、大島淑子、小高陽樹、井上貴文、功刀浩
- Organizer
  第37回日本神経科学大会 Neuroscience 2014
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] 培養大脳皮質ニューロンに対するカベルゴリン（ドーパミンD2受容体アゴニスト）の神経保護効果の解析
- Author(s)
  小髙陽樹、沼川忠広、安達直樹、大島淑子、中島進吾、片沼佑介、井上貴文、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Decreased release of neurotransmitter induced by BDNF in cultured cortical neurons from IUGR(intrauterine growth retardation) rats
- Author(s)
  Ooshima Y， Numakawa T， Matsumoto T， Chiba S， Furuta M，Izumi A， Ninomiya-Baba M， Odaka H， Hashido K， Adachi N， Kunugi H.
- Organizer
  第37回日本神経科学大会 Neuroscience 2014.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] MicroRNA induction by basic fibroblast growth factor in pure astroglial cultures.
- Author(s)
  Nakajima S, Numakawa T, Yamamoto N, Yoshiko O, Odaka H, Hashido K, Adachi N, Kunugi H.
- Organizer
  CSHA/NGF2014 Joint Conference on Nerve Growth Factor and Related Neurotrophic Factors: Emerging Concepts, New Mechanism, Novel Technologies
- Place of Presentation
  Suzhou, PR China
- Year and Date
  2014-06-23 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] グルココルチコイドによる脳由来神経栄養因子（BDNF）の細胞内輸送制御
- Author(s)
  安達直樹、沼川忠広、中島進吾、大島淑子、小高陽樹、片沼祐介、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] グルココルチコイドによる脳由来神経栄養因子（BDNF）の細胞内輸送制御
- Author(s)
  安達直樹、沼川忠広、中島進吾、大島淑子、小高陽樹、片沼祐介、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Glucocorticoid stress, neurotrophin, and pathogenesis of psychiatric disorders
- Author(s)
  Tadahiro Numakawa
- Organizer
  熊本大学リエゾンラボ研究会／リーディングプログラム：HIGO最先端研究セミナー
- Place of Presentation
  熊本大学
- Invited
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] Influence of chronic glucocorticoid exposure on proliferation and differentiation of rat neural stem cells in vitro
- Author(s)
  Odaka H, Numakawa T, Yoshimura A, Adachi N, Nakajima S, Era T, Inoue T, Kunugi H.
- Organizer
  熊本医学・生物科学国際シンポジウム
- Place of Presentation
  熊本市医師会館（熊本県）
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] アストログリア細胞においてbFGF投与で増加したマイクロRNAの機能的役割
- Author(s)
  沼川忠広、中島進吾、山本宣子、大島淑子、小高陽樹、橋戸和夫、安達直樹、功刀浩
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] MicroRNA induction by basic fibroblast growth factor in pure astroglial cultures.
- Author(s)
  Nakajima S, Numakawa T, Yamamoto N, Yoshiko O, Odaka H, Hashido K, Adachi N, Kunugi H.
- Organizer
  CSHA/NGF2014 Joint Conference on Nerve Growth Factor and Related Neurotrophic Factors: Emerging Concepts, New Mechanism, Novel Technologies
- Place of Presentation
  Suzhou, PR China
- Year and Date
  2014-06-23 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24300139
[Presentation] The mechanisms behind deficits in BDNF function after phencyclidine exposure
- Author(s)
  Adachi N, Numakawa T, Kumamaru E, Itami C, Chiba S, Iijima Y, Richards M, Katoh-Semba R, Kunugi H.
- Organizer
  CSHA/NGF2014 Joint Conference on Nerve Growth Factor and Related Neurotrophic Factors: Emerging Concepts, New Mechanism, Novel Technologies
- Place of Presentation
  Suzhou, PR China
- Year and Date
  2014-06-23 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Possible of CD63 in synaptic function of rat cortical neurons.
- Author(s)
  吉村文, 沼川忠広, 中島進吾, 安達直樹, 川又理樹, 落谷孝広, 功刀浩, 玉井淑貴
- Organizer
  第３６回日本生物学的精神医学会　第５７回日本神経化学会大会　合同年会
- Place of Presentation
  奈良県文化会館/奈良県新公会堂（奈良県）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25640019
[Presentation] Glial miR expression following basic fibroblast growth factor application in astrocytes
- Author(s)
  Yamamoto N， Numakawa T， Nakajima S, Ooshima Y, Odaka H， Hashido K， Adachi N， Kunugi H.
- Organizer
  第37回日本神経科学大会 Neuroscience 2014.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25640019
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]

1. Kajihara Ryutaro (00738221)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. Kido Jun (70721215)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. MASTUMOTO Shirou (70467992)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. 小高陽樹 (40831243)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
5. 曽我美南 (80768002)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. KUNUGI Hiroshi (40234471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FUJII Takashi (10450610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. CHIBA Shuichi (00510380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. NAGATANI Miyako (20450611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ITAMI Chiaki (90392430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. HASHIDO Kazuo (70270650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. ERA Takumi (00273706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ENDO Fumio (00176801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中村公俊 (30336234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 安達直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. くぬ刀浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Numakawa Tadahiro 沼川 忠広

NUMAKAWA Tadahiro 沼川 忠広

Research Projects

Research Products

Co-Researchers

ライソゾーム病の神経障害における細胞内カルシウム亢進と興奮毒性の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

iPS細胞を用いたメラノーマに対する新規がん免疫療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of the interaction between microglia and neuron in the defected neuronal function in the lysosomal storage diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel pathological analysis and medicine in neuropathic Gaucher disease.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel medicine using iPS cells derived from Gaucher disease type II patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of cellular/molecular pathophysiology of brain disorders using human brain organoids established from iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drug Development for GM1 Gangliosidosis using the patients-derived iPS cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Contribution of brain-specific miRs in the neuronal and glial function and possible transmission of miRs between cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on cellular and molecular mechanism behind the depressive behavior by approaching the functional interaction between stress hormone and BDNF.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism underlying the glucocorticoid-decreased function of neurotrophic factor in depression.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of neurotrophin receptor p75 in psychiatric diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

うつ病関連分子p75の一塩基多型に起因した機能変化の細胞、分子生物学的解析。Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] "Roles of Trk receptors, tyrosine kinase receptors for neurotrophins, in the developing CNS" , CHAPTER 3 in book "Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders"2023

Author(s)

Total Pages

Numakawa Tadahiro 沼川忠広

NUMAKAWA Tadahiro 沼川忠広