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TOMIZUKA KAZUMA  冨塚 一磨

ORCIDConnect your ORCID iD *help
Researcher Number 40444640
Other IDs
Affiliation (Current) 2025: 東京薬科大学, 生命科学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 東京薬科大学, 生命科学部, 教授
Review Section/Research Field
Principal Investigator
Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 38060:Applied molecular and cellular biology-related / 0601:Agricultural chemistry and related fields
Except Principal Investigator
Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords
Principal Investigator
表現型スクリーニング / ゲノム編集 / R-spondin / ヒト人工染色体 / 分子進化 / 機能抗体 / 進化工学 / モノクローナル抗体 / 染色体工学 / Wnt/βカテニンシグナル … More / CRISPR-Cas9 / 免疫グロブリン / VHH / ペプチド / 抗体医薬 / 指向性進化 / ペプチド医薬 / Wnt/βカテニンシグナル / 相補性決定領域 / ヒト抗体 / 間葉系幹細胞 / 再生医療 … More
Except Principal Investigator
R-Spondin / 造血幹細胞移植 / GVHD / 抗体 / ナノバブル / LRP1 / 緑内障 / Gilteriinib / ミトコンドリア / 慢性GVHD / 白血病 / 幹細胞 / カルシニューリン阻害剤 / CAR-T / GVL / 疲弊T細胞 / 腸幹細胞 / 炎症記憶 / VOD/SOS / 肝GVHD / マクロファージ / 胆管上皮幹細胞 / オーガノイド / 肝幹細胞 / TGF-beta Less
  • Research Projects

    (6 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (8 People)
  •  ゲノム編集誘導性分子多様化による、機能抗体・ペプチド表現型スクリーニングシステムPrincipal Investigator

    • Principal Investigator
      冨塚 一磨
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
      Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Development of a non-invasive glaucoma treatment using ultrasonic nanobubbles associated with anti-LRP1 antibody

    • Principal Investigator
      林 秀樹
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Study on mechanisms of immune and tissue tolerance after allogeneic hematopoietic stem cell transplantation

    • Principal Investigator
      豊嶋 崇徳
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Hokkaido University
  •  Title of Research Project

    • Principal Investigator
      Teshima Takanori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      Hokkaido University
  •  Development of induciblydiversified antibody-expressing cell library that enables antibody phenotypic screeningPrincipal Investigator

    • Principal Investigator
      TOMIZUKA KAZUMA
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38060:Applied molecular and cellular biology-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  ヒト人工染色体(HAC)ベクターによる組織再生能を高めた間葉系幹細胞の造成Principal Investigator

    • Principal Investigator
      冨塚 一磨
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0601:Agricultural chemistry and related fields
    • Research Institution
      Tokyo University of Pharmacy and Life Science

All 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] R-Spondin1 protects gastric stem cells and mitigates gastric GVHD in allogeneic hematopoietic stem cell transplantation2024

    • Author(s)
      Hayase Eiko、Ara Takahide、Saito Yumika、Takahashi Shuichiro、Yoshioka Kosuke、Ohigashi Hiroyuki、Ogasawara Reiki、Yokoyama Emi、Yamakawa Tomohiro、Ebata Ko、Hasegawa Yuta、Tomizuka Kazuma、Teshima Takanori
    • Journal Title

      Blood Advances

      Volume: 8 Issue: 3 Pages: 725-731

    • DOI

      10.1182/bloodadvances.2023011034

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18296, KAKENHI-PROJECT-21K16259, KAKENHI-PROJECT-23K21439
  • [Presentation] 染色体工学技術の抗体研究への応用(6)CDR-H3を標的としたゲノム編集誘導性分子多様化によるMammalian displayシステムの構築2023

    • Author(s)
      櫻井 諒一、円子 大夢、橋本 七海、宇野 愛海、林 秀樹、香月 康弘、堀田 秋津、冨塚 一磨
    • Organizer
      第2回日本抗体学会 20231201 鹿児島
    • Data Source
      KAKENHI-PROJECT-23K24220
  • [Presentation] 抗体重鎖相補性決定領域3を標的とした相同組換えによる新規抗体ディスプレイの開発2023

    • Author(s)
      櫻井 諒一、円子 大夢、橋本 七海、宇野 愛海、林 秀樹、香月 康弘、堀田 秋津、冨塚 一磨
    • Organizer
      日本ゲノム編集学会 第8回大会20230606 東京
    • Data Source
      KAKENHI-PROJECT-23K24220
  • [Presentation] 染色体工学技術の抗体研究への応用(9)相補性決定領域を標的としたアミノ酸挿入型・置換型ゲノム編集による新規抗体の探索2022

    • Author(s)
      櫻井 諒一、円子 大夢、橋本 七海、宇野 愛海、林 秀樹、香月 康弘、堀田 秋津、冨塚 一磨
    • Organizer
      第1回 日本抗体学会
    • Data Source
      KAKENHI-PROJECT-23K24220
  • [Presentation] 染色体工学技術応用(13):抗体の表現型スクリーニングを可能にする、多様化誘導型抗体発現細胞ライブラリの開発2021

    • Author(s)
      橋本七海、笹川航、宇野愛海、里深博幸、香月康宏、堀田秋津、冨塚一磨
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H02924
  • [Presentation] 染色体工学技術応用(14):機能ペプチドの表現型スクリーニングを行う多様化誘導型発現細胞ライブラリの開発2021

    • Author(s)
      円子 大夢、奥山 優希、橋本 七海、宇野 愛海、石津 由紀、香月 康宏、堀田 秋津、冨塚 一磨
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H02924
  • 1.  Teshima Takanori (40284096)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  堀田 秋津 (50578002)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  香月 康宏 (90403401)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  坂本 直哉 (10334418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  山田 勇磨 (60451431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  林 秀樹 (90508657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  吉川 大和 (20274227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  根岸 洋一 (50286978)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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