Ohta Hiromitsu 太田洋充

… Alternative Names

太田洋充オオタヒロミツ

OHTA Hiromitsu 太田洋充

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Researcher Number	40451562
Other IDs	https://orcid.org/0000-0001-9893-0254
Affiliation (Current)	2025: 自治医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 自治医科大学, 医学部, 講師 2021 – 2023: 自治医科大学, 医学部, 講師 2016 – 2019: 自治医科大学, 医学部, 講師 2012 – 2015: 埼玉医科大学, 医学部, 講師 2012: 東北大学, 大学院・医学系研究科, 助教 2009 – 2010: Tohoku University, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator びまん性肺胞障害 / MUC4 / lectin / 好中球性炎症 / ムチン / 薬剤性肺障害 / びまん性肺胞上皮障害 / 肺障害 / 血清マーカー / Mucin 4 … More / 糖鎖 / 内科 / 遺伝子 / 発現ベクター / 気道上皮細胞 / 遺伝子解析 / 次世代シークエンス / 遺伝子多型 / 間質性肺炎急性増悪 / 初代気道上皮細胞 / MUC4発現ベクター / MUC4のシークエンス / EGFR-TKI / 特発性間質性肺炎急性増悪 / 急性呼吸不全 / 細胞間接着分子 / 上皮細胞 / 肺胞上皮障害 / タイトジャンクション / 肺線維症 / 非閉塞性肺疾患 / ARDSタイトジャンクション / 間質性肺炎 … More Except Principal Investigator 非閉塞性肺疾患癌 / SP-D / miRNA / 肺幹細胞 / バイオマーカー / 間質性肺炎 / micro RNA / 循環線維細胞 / Fibrocyte / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患 Less

Investigation of the Function and Clinical Significance of Mucins in Severe Lung InjuryPrincipal Investigator
- Principal Investigator
  
  太田洋充
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Jichi Medical University
Mucin 4, expressed in the airways, suppresses neutrophilic inflammationPrincipal Investigator
- Principal Investigator
  
  Ohta Hiromitsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Jichi Medical University
Genetic polymorphism of MUC4 is related to the severity of neutrophilic inflammation in the lungPrincipal Investigator
- Principal Investigator
  
  Hiromitsu Ohta
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Jichi Medical University
The molecular mechanism of drug-induced lung injury caused by the genetic polymorphism of MUC4Principal Investigator
- Principal Investigator
  
  Ohta Hiromitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Jichi Medical University
  Saitama Medical University
Alveolar barrier functionPrincipal Investigator
- Principal Investigator
  
  OHTA Hiromitsu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Saitama Medical University
Pathogenesis and control of circulating fibrocytes and miRNAs causing interstitial/airway fibrosis and initiating/promoting cancer in the lung
- Principal Investigator
  
  EBINA Masahito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Investigation of mechanism of acute exacerbation of interstitial pneumonia. Alveolar barrier dysfunction was observed in fibrotic lungPrincipal Investigator
- Principal Investigator
  
  OHTA Hiromitsu
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University

All 2023 2019 2018 2017 2016 2012 2011 2010 2009

All Journal Article Presentation Book

[Book] 「上皮細胞生死にかかわる分子機構」　呼吸器内科　Vol.36 　No.22019
- Author(s)
  太田洋充、萩原弘一
- Total Pages
  4
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-17K09664
[Book] 「上皮細胞生死の分子生物学的機構と間質性肺炎」　間質性肺炎・肺線維症と類縁疾患第4巻2018
- Author(s)
  太田洋充、萩原弘一.
- Total Pages
  380
- Publisher
  中山書店
- ISBN
  4521745288
- Data Source
  KAKENHI-PROJECT-17K09664
[Book] 分子呼吸器病　2017年3月号　ムチンど気道上皮防御機構2017
- Author(s)
  太田洋充、萩原弘一
- Total Pages
  4
- Publisher
  先端医学社
- ISBN
  9784865502503
- Data Source
  KAKENHI-PROJECT-17K09664
[Journal Article] 肺循環・肺損傷　ムチンと気道上皮防御機構2017
- Author(s)
  太田洋充、萩原弘一
- Journal Title
  
  分子呼吸器病学
  
  Volume: 21 Pages: 61-63
- Data Source
  KAKENHI-PROJECT-26461196
[Journal Article] A highly specific and sensitive massive parallel sequencer-based test for somatic mutations in non-small cell lung cancer.2017
- Author(s)
  Inoue Y, Shiihara J, Miyazawa H, Ohta H, Higo M, Nagai Y,　Kobayashi K, Saijo Y, Tsuchida M, Nakayama M, Hagiwara K
- Journal Title
  
  PLoS one
  
  Volume: 12 Pages: 1371-1371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09664
[Journal Article] Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis2012
- Author(s)
  Ohta H, Ebina M, et al
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390164
[Journal Article] Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis2012
- Author(s)
  Ohta H, Chiba S, Ebina M, Furuse M, Nukiwa T
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390164
[Journal Article] A normal range of KL-6/MUC1 independent elevated SP-D indicates a better prognosis in idiopathic pulmonary fibrosis.2011
- Author(s)
  Hisata S, Kimura Y, Shibata N, Ono S, Kobayashi T, Chiba S, Ohta H, Nukiwa T, Ebina M.
- Journal Title
  
  Pulmonary Medicine
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790764
[Journal Article] Gradual increase of high mobility group protein B 1 (HMGB1) in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis2011
- Author(s)
  Ebina M, Taniguchi H, Miyasho T, Yamada S, Shibata N, Ohta H, Hisata S, Hirota N, Nishimura H, Ishizaka A, Maruyama I, Takashi K, Nukiwa T
- Journal Title
  
  Pulmonary Med
  
  Volume: 916486 Pages: 1-9
- DOI
  10.1155/2011/916486
- NAID
  120003072907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390164, KAKENHI-PROJECT-23390412
[Journal Article] Gradual increase of high mobility group protein B 1 (HMGB 1) in the lungs after the onset of acute exacerbation of idiop athic pulmonary fibrosis.2011
- Author(s)
  Ebina M, Taniguchi H, Miyasho T, Yamada S, Shibata N, Ohta H, Hisata S, Hirota N, Nishimura H, Ishizaka A, Maruyama I, Takashi K, Nukiwa T.
- Journal Title
  
  Pulmonary Medicine
  
  Volume: on line Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390164
[Journal Article] The disappearance of subpleural and interlobular lymphatics in idiopathic nulmonarv fibrosis.2011
- Author(s)
  Ebina M, Shibata N, Ohta H, et al.
- Journal Title
  
  Lymphatic Research and Biology
  
  Volume: 8 Pages: 199-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390164
[Journal Article] A normal range of KL-6/MUC1 independent elevated SP-D indicates a better prognosis in idiopathic pulmonary fibrosis.2011
- Author(s)
  Hisata S, Kimura Y, Shibata N, Ono S, Kobayashi T, Chiba S, Ohta H, Nukiwa T. Ebina M.
- Journal Title
  
  Pulmonary Med
  
  Volume: on line Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390164
[Journal Article] Gradual increase of high mobility group protein B1 (HMGB1) in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis.2011
- Author(s)
  Ebina M, Taniguchi H, Miyasho T, Yamada S, Shibata N, Ohta H, Hisata S, Hirota N, Nishimura H, Ishizaka A, Maruyama I, Takashi K, Nukiwa T.
- Journal Title
  
  Pulmonary Medicine
  
  Pages: 1-9
- NAID
  120003072907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790764
[Journal Article] A normal range of KL-6/MUC1 independent elevated SP-D indicates a better prognosis in idiopathic pulmonary fibrosis2011
- Author(s)
  Hisata S, Kimura Y, Shibata N, Ono S, Kobayashi T, Chiba S, Ohta H, Nukiwa T, Ebina M
- Journal Title
  
  Pulmonary Med
  
  Volume: 806014 Pages: 1-7
- DOI
  10.1155/2011/806014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390164
[Journal Article] A normal range of KL-6/MUC1 independent elevated SP-D indicates a better prognosis in idiopathic pulmonary fibrosis.2011
- Author(s)
  Hisata S, Kimura Y, Shibata N, Ono S, Kobayashi T, Chiba S, Ohta H Nukiwa T, Ebina M.
- Journal Title
  
  Pulmonary Med
  
  Volume: (On line) Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790764
[Journal Article] The disappearance of subpleural and inter lobular lymphatics in idiopathic pulmon ary fibrosis.2010
- Author(s)
  Ebina M, Shibata N, Ohta, H, et.al.
- Journal Title
  
  Lymphat Res Biol 1809卷
  
  Pages: 176-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790764
[Journal Article] The disappearance of subpleural and interlobular lymphatics in idiopathic pulmonary fibrosis.2010
- Author(s)
  Ebina M, Shibata N, Ohta, H, et al
- Journal Title
  
  Lymphat Res Biol
  
  Volume: 1809 Pages: 176-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790764
[Presentation] 正常気管支上皮細胞におけるMUC4の発現調節2023
- Author(s)
  野村基子　太田洋充　椎原淳　前田悠希　長井良昭　萩原弘一　山口泰弘
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K08163
[Presentation] Genetic polymorphism of variable number tandem repeat region of Mucin 4 might have some relevance to severe lung injury2019
- Author(s)
  H. Ohta, J. Shiihara, F. Kudo, M. Nomura, Y. Mizushina, O. Fumiyoshi, S. Koyama, K. Hagiwara
- Organizer
  American Thoracic Society 2019 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09664
[Presentation] MUC4 Variable Number Tandem Repeat Polymorphisms and severe lung injury2017
- Author(s)
  S. Shiihara, H. Ohta , K. Kudo, K. Mizushina, T. Miwa, H. Ohyanagi, S. Koyama, K. Hagiwara
- Organizer
  Congress OF Asian Pacific Society of Respirology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09664
[Presentation] 当院の進展型肺小細胞癌における間質性肺炎の有無の影響及び予後因子の検討2016
- Author(s)
  岩井悠紀、渡辺恭孝、工藤史明、三輪千尋、長井良昭、太田洋充、小山信一郎、萩原弘一、小山信之
- Organizer
  第57回日本肺癌学会学術集会
- Place of Presentation
  福岡（福岡サンパレス、福岡国際センター）
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-26461196
[Presentation] Bleomycin-Induced Lung Injury Causes Disturbance of Tight Junction of Alveolar Epithelial Cells2011
- Author(s)
  Ohta H, Ebina M, Nukiwa T
- Organizer
  ATS 2011
- Place of Presentation
  Denver,USA
- Data Source
  KAKENHI-PROJECT-22390164
[Presentation] Lung Cancer in Patients with Pulmoanry Fibrosis2010
- Author(s)
  Hiromitsu Obta, et al
- Organizer
  American thorasic society International Conferance
- Place of Presentation
  New Orleans(America)
- Data Source
  KAKENHI-PROJECT-21790764
[Presentation] Lung Cancer in Patients with Pulmonary Fibrosis2010
- Author(s)
  Hiromitsu Ohta, et.al.
- Organizer
  American thoracic society International conference
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21790764
[Presentation] Pivotal Roles of Transforming Growth Factor-beta 1 in Barrier Dysfunction of Alveolar Walls in Lung Injury Prior to Fibrogenesis2009
- Author(s)
  Hiromitsu Ohta, et.al.
- Organizer
  American thoracic society International conference
- Place of Presentation
  Sandiego
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-21790764
[Presentation] Pivotal Roles of Transforming Growth Factor-beta 1 in Barrier Dysfunction of Alveolar Walls in Lung Injury Prior to Fibrogenesis2009
- Author(s)
  太田洋充, ほか
- Organizer
  American thoracic society International conferance
- Place of Presentation
  SAN DIEGO CONVENTION CENTER アメリカ
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-21790764

1. EBINA Masahito (10280885)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. 萩原弘一 (00240705)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. KONDOH Takahshi (10195901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OKOUCHI Shinya (40375035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SATO Yasufumi (50178779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. INOUE Akira (70361087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAMADA Tsutomu (80396473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HISATA Shu (60466571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 椎原淳 (20737241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 鈴木朋子 (10400342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山口泰弘 (60376473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ohta Hiromitsu 太田 洋充

太田 洋充 オオタ ヒロミツ

OHTA Hiromitsu 太田 洋充

Research Projects

Research Products

Co-Researchers

Investigation of the Function and Clinical Significance of Mucins in Severe Lung InjuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mucin 4, expressed in the airways, suppresses neutrophilic inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic polymorphism of MUC4 is related to the severity of neutrophilic inflammation in the lungPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular mechanism of drug-induced lung injury caused by the genetic polymorphism of MUC4Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alveolar barrier functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis and control of circulating fibrocytes and miRNAs causing interstitial/airway fibrosis and initiating/promoting cancer in the lung

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of mechanism of acute exacerbation of interstitial pneumonia. Alveolar barrier dysfunction was observed in fibrotic lungPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 「上皮細胞生死にかかわる分子機構」 呼吸器内科 Vol.36 No.22019

Author(s)

Total Pages

Publisher

Data Source

[Book] 「上皮細胞生死の分子生物学的機構と間質性肺炎」 間質性肺炎・肺線維症と類縁疾患 第4巻2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 分子呼吸器病 2017年3月号 ムチンど気道上皮防御機構2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] 肺循環・肺損傷 ムチンと気道上皮防御機構2017

Author(s)

Journal Title

Data Source

[Journal Article] A highly specific and sensitive massive parallel sequencer-based test for somatic mutations in non-small cell lung cancer.2017

Author(s)

Journal Title

Data Source

[Journal Article] Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis2012

Author(s)

Journal Title

Data Source

[Journal Article] Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis2012

Author(s)

Journal Title

Ohta Hiromitsu 太田洋充

太田洋充オオタヒロミツ

OHTA Hiromitsu 太田洋充

[Book] 「上皮細胞生死にかかわる分子機構」　呼吸器内科　Vol.36 　No.22019

[Book] 「上皮細胞生死の分子生物学的機構と間質性肺炎」　間質性肺炎・肺線維症と類縁疾患第4巻2018

[Book] 分子呼吸器病　2017年3月号　ムチンど気道上皮防御機構2017

[Journal Article] 肺循環・肺損傷　ムチンと気道上皮防御機構2017