TSUIJI HITOMI 築地仁美

… Alternative Names

TSUIJI Hitomi 築地仁美

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Researcher Number	40455358
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 大学院薬学研究科, 研究員 2025: 名古屋市立大学, 医薬学総合研究院(薬学), 研究員 2025: 武蔵野大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 武蔵野大学, 薬学部, 教授 2023 – 2024: 愛知学院大学, 薬学部, 教授 2022: 名古屋市立大学, 医薬学総合研究院(薬学), 研究員 2019 – 2021: 名古屋市立大学, 医薬学総合研究院(薬学), 講師 2016 – 2018: 名古屋市立大学, 大学院薬学研究科, 講師 … More 2014 – 2015: 名古屋市立大学, 薬学研究科(研究院), 講師 2013: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員 2011 – 2012: 独立行政法人理化学研究所, 運動ニューロン変性研究チーム, 研究員 2007 – 2008: The Institute of Physical and Chemical Research, 中川独立主幹研究ユニット, ユニット研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Nerve anatomy/Neuropathology / Neurochemistry/Neuropharmacology / Molecular biology Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator 筋萎縮性側索硬化症 / TDP-43 / FUS / ALS / RNA結合タンパク質 / 脊髄性筋萎縮症 / RNA代謝 / SMA / SMN / スプライソソーム … More / スプライシング / Ataxin-2 / パルブアルブミン / 凝集 / 神経変性疾患 / 神経変性 / 加齢 / 抑制性介在ニューロン / 前頭側頭葉変性症 / RNA代謝異常 / 運動ニューロン / splicing / snRNA / RNA / snRNP / spliceosome / 神経発生 / RNA結合蛋白質 / mRNA様ノンコーシングRNA / ブランチポイント / 核内構造体 / 神経 / 核外輸送 / 核内繋留 / mRNA / ノンコーディングRNA … More Except Principal Investigator ALS / 非ドメイン型バイオポリマー / 神経変性疾患 / 天然変性タンパク質 / Heroタンパク質 Less

Mechanism and application of Hero proteins
- Principal Investigator
  
  泊幸秀
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
Development of Therapeutic Strategies for Amyotrophic Lateral Sclerosis (ALS) through Modulation of RNA-Binding Protein LevelsPrincipal Investigator
- Principal Investigator
  
  TSUIJI Hitomi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Aichi Gakuin University
  Nagoya City University
Elucidation of pathophysiological implications of interneuron degeneration in frontotemporal dementiaPrincipal Investigator
- Principal Investigator
  
  Tsuiji Hitomi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Common defects of RNA metabolism in motor neuron diseases SMA and ALSPrincipal Investigator
- Principal Investigator
  
  Tsuiji Hitomi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Nagoya City University
  Institute of Physical and Chemical Research
Defective RNA metabolism in motor neurons from Amyotrophic Lateral Scelosis patientsPrincipal Investigator
- Principal Investigator
  
  TSUIJI Hitomi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The Institute of Physical and Chemical Research
Functional analysis of Gomafu, the mRNA-like non-coding RNAPrincipal Investigator
- Principal Investigator
  
  TSUIJI Hitomi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Molecular biology
- Research Institution
  The Institute of Physical and Chemical Research

[Book] Animal Biotechnology2014
- Author(s)
  Hitomi Tsuiji and Koji Yamanaka
- Total Pages
  18
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-25430055
[Journal Article] dCas13-mediated translational repression for accurate gene silencing in mammalian cells2024
- Author(s)
  Apostolopoulos Antonios、Kawamoto Naohiro、Chow Siu Yu A.、Tsuiji Hitomi、Ikeuchi Yoshiho、Shichino Yuichi、Iwasaki Shintaro
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-18
- DOI
  10.1038/s41467-024-46412-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ2175, KAKENHI-PROJECT-20K07016, KAKENHI-PLANNED-21H05278, KAKENHI-PROJECT-22H04922
[Journal Article] The Plasma Membrane Polarity Is Higher in the Neuronal Growth Cone than in the Cell Body of Hippocampal and Cerebellar Granule Neurons2023
- Author(s)
  Oya Shintaro、Korogi Katsunari、Kohno Takao、Tsuiji Hitomi、Danylchuk Dmytro I.、Klymchenko Andrey S.、Niko Yosuke、Hattori Mitsuharu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 12 Pages: 1820-1825
- DOI
  10.1248/bpb.b23-00592
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-12-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06119, KAKENHI-PROJECT-20K07016, KAKENHI-PROJECT-23K27324
[Journal Article] <i>C9ORF72</i> dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein2021
- Author(s)
  Kato Yuma、Yokogawa Minnie、Nakagawa Ikuma、Onodera Kazunari、Okano Hideyuki、Inoue Haruhisa、Hattori Mitsuharu、Okada Yohei、Tsuiji Hitomi
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.03.24.436890
- Open Access
- Data Source
  KAKENHI-PROJECT-20K07016
[Journal Article] Direct evidence that Ataxin-2 is a translational activator mediating cytoplasmic polyadenylation2020
- Author(s)
  Hiroto Inagaki 1 , Nao Hosoda 1 , Hitomi Tsuiji 2 , Shin-Ichi Hoshino 3
- Journal Title
  
  J Biol Chem .
  
  Volume: 20;295(47) Pages: 15810-15825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07016
[Journal Article] TDP-43 accelerates age-dependent degeneration of interneurons2017
- Author(s)
  Tsuiji Hitomi、Inoue Ikuyo、Takeuchi Mari、Furuya Asako、Yamakage Yuko、Watanabe Seiji、Koike Masato、Hattori Mitsuharu、Yamanaka Koji
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 14972-14972
- DOI
  10.1038/s41598-017-14966-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08280, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-26293208, KAKENHI-PROJECT-17H04986, KAKENHI-PROJECT-16H06280
[Journal Article] Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.2016
- Author(s)
  Naoki Ichiyanagi, Koki Fujimori, Masato Yano, Chikako Ishihara-Fujisaki, Takefumi Sone, Tetsuya Akiyama, Yohei Okada, Wado Akamatsu, Takuya Matsumoto, Mitsuru Ishikawa, Yoshinori Nishimoto, Yasuharu Ishihara, Tetsushi Sakuma, Takashi Yamamoto, Hitomi Tsuiji, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
- Journal Title
  
  Stem Cell Reports
  
  Volume: 6 Issue: 4 Pages: 496-510
- DOI
  10.1016/j.stemcr.2016.02.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-25430055, KAKENHI-PROJECT-26830018, KAKENHI-PROJECT-15H04278, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-25293199, KAKENHI-PLANNED-26117007, KAKENHI-PUBLICLY-15H01568, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K07247
[Journal Article] There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS.2016
- Author(s)
  Gitler AD, Tsuiji H.
- Journal Title
  
  Brain Res
  
  Volume: S0006-8993(16) Pages: 30197-4
- DOI
  10.1016/j.brainres.2016.04.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430055
[Journal Article] Spliceosome integrity is defective in motor neuron disease ALS and SMA2013
- Author(s)
  Tsuiji H., Iguchi Y., Furuya A., Kataoka A., Hatsuta H., Atsuta N., Tanaka F., Hashizume Y., Akatsu H., Murayama S., Sobue G., Yamanaka K
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 5(2) Pages: 221-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700455
[Journal Article] Spliceosome integrity is defective in the motor neuron diseases ALS and SMA2013
- Author(s)
  Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H, Murayama S, Sobue G, Yamanaka K
- Journal Title
  
  EMBO Mol Med
  
  Volume: 5 Issue: 2 Pages: 221-234
- DOI
  10.1002/emmm.201202303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-23700455, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24700371, KAKENHI-PLANNED-23111006
[Presentation] 筋萎縮性側索硬化症ALS患者ニューロンにおけるRNA顆粒の異常形成の分子機構解明とその制御2024
- Author(s)
  築地仁美
- Organizer
  日本薬学会第114年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07016
[Presentation] 筋萎縮性側索硬化症原因タンパク質TDP-43の凝集を抑制する分子の探索2023
- Author(s)
  宮田識園、河鰭公孝、玉井理也、小林祐基、築地仁美
- Organizer
  第69回日本薬学会東海支部大会
- Data Source
  KAKENHI-PROJECT-20K07016
[Presentation] C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron proteins2023
- Author(s)
  Hitomi Tsuiji
- Organizer
  The 19th Annual Congress of International Drug Discovery Science and Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07016
[Presentation] Disruption of RNA metabolism in motor neuron diseases, ALS and SMA2022
- Author(s)
  Hitomi Tsuiji
- Organizer
  OIST Workshop Axonal Degeneration and Regeneration
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07016
[Presentation] Disruption of RNA metabolism in motor neuron diseases2022
- Author(s)
  Hitomi Tsuiji
- Organizer
  The 28th Tokyo RNA Club
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07016
[Presentation] C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein2022
- Author(s)
  Hitomi Tsuiji
- Organizer
  第45回日本神経科学大会／第65回日本神経化学会大会／第32回日本神経回路学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07016
[Presentation] C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein2021
- Author(s)
  Tsuiji H. , Kato Y., Yokogawa M., Nakagawa I., Onodera K., Okano H., Inoue H., Hattori M., Okada Y.
- Organizer
  The 1st China-Japan-Korea International Meeting/The 44th Annual Meeting of the Japan Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07016
[Presentation] TDP-43 accelerates age-dependent degeneration of interneurons2018
- Author(s)
  Hitomi Tsuiji, Ikuyo Inoue, Asako Furuya, Mari Takeuchi, Yuko Yamakage, Mitsuharu Hattori, Koji Yamanaka
- Organizer
  12th Brain Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08280
[Presentation] RNA代謝異常が引き起こす神経変性疾患の発症解明へ向けて2018
- Author(s)
  築地仁美
- Organizer
  第37回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08280
[Presentation] TDP-43 accelerates age-dependent degeneration of interneurons2018
- Author(s)
  Hitomi Tsuiji
- Organizer
  第41回　日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08280
[Presentation] TDP-43 accelerates age-dependent degeneration of interneurons2017
- Author(s)
  Hitomi Tsuiji, Ikuyo Inoue, Asako Furuya, Mari Takeuchi, Yuko Yamakage, Mitsuharu Hattori, Koji Yamanaka
- Organizer
  第40回　日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K08280
[Presentation] Interneuron degeneration in TDP-43 transgenic mice displaying impaired memory2016
- Author(s)
  Hitomi Tsuiji, Ikuyo Inoue, Asako Furuya, Mari Takeuchi, Yuko Yamakage, Mitsuharu Hattori, Koji Yamanaka
- Organizer
  第39回　日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Interneuron degeneration in TDP-43 transgenic mice displaying impaired memory2016
- Author(s)
  Hitomi Tsuiji, Ikuyo Inoue, Asako Furuya, Mari Takeuchi, Yuko Yamakage, Mitsuharu Hattori, Koji Yamanaka
- Organizer
  The 21st Annual Meeting of the RNA Society
- Place of Presentation
  京都国際会館
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Interneuron degeneration in TDP-43 transgenic mice displaying impaired memory2016
- Author(s)
  Hitomi Tsuiji, Ikuyo Inoue, Asako Furuya, Mari Takeuchi, Yuko Yamakage, Mitsuharu Hattori, Koji Yamanaka
- Organizer
  11th Brain Research Conference
- Place of Presentation
  Paradise Point, San Diego, CA
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] 筋萎縮性側索硬化症ALSにおけるスプライソソーム異常2015
- Author(s)
  築地仁美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] 前頭側頭葉変性症モデルマウスの脳の組織学的な解析2015
- Author(s)
  竹内真理、山中宏二、築地仁美、服部光治
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部
- Place of Presentation
  名古屋（愛知県）
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] 筋萎縮性側索硬化症ALSを引き起こす変異型FUS/TLSの解析2015
- Author(s)
  近藤佑多、古屋亜佐子、内匠透、山中宏二、築地仁美、服部光治
- Organizer
  第61回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋（愛知県）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Interneuron degeneration in TDP-43 transgenic mice displaying impaired memory2015
- Author(s)
  Hitomi Tsuiji, Ikuyo Inoue, Asako Furuya, Mitsuharu Hattori, Koji Yamanaka
- Organizer
  10th Brain Research Conference
- Place of Presentation
  シカゴ（アメリカ）
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Defects in RNA Metabolism in Neurodegenerative Diseases2014
- Author(s)
  Hitomi Tsuiji
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11
- Invited
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] 運動神経変性疾患に共通するスプライシング経路の破たん2013
- Author(s)
  築地仁美
- Place of Presentation
  京都大学医学部(京都)
- Year and Date
  2013-01-25
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Cell-type specific gene expression changes in TDP-43 transgenic mice displaying memory defect.2013
- Author(s)
  Tsuiji H., Inoue I., Kataoka A., Furuya A., Yamanaka K.
- Organizer
  RNA Biology in Neurological diseases
- Place of Presentation
  カリフォルニア、米国
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Spliceosome integrity is defective in motor neuron disease ALS and SMA2013
- Author(s)
  Tsuiji H., Iguchi Y., Furuya A., Kataoka A., Hatsuta H., Atsuta N., Tanaka F.Hashizume Y., Akatsu H., Murayama S., Sobue G., Yamanaka K.
- Organizer
  第３６回日本神経科学大会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Spliceosome integrity is defective in motor neuron disease ALS and SMA.2013
- Author(s)
  Tsuiji H., Iguchi Y., Furuya A., Murayama S., Sobue G., Yamanaka K.
- Organizer
  RNA 2013 The 18th Annual Meeting of the RNA Society
- Place of Presentation
  Davos, Switzerland
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] 神経変性疾患モデルであるTDP-43トランスジェニックマウスにおけるTDP-43標的遺伝子の同定2013
- Author(s)
  築地仁美、井上郁代、古屋亜佐子、山中宏二
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] 運動神経変性疾患に共通するスプライソソーム異常2012
- Author(s)
  築地仁美
- Organizer
  第14回RNA学会年会
- Place of Presentation
  東北大学、仙台
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Spliceosome integrity is defective in motor neuron disease ALS and SMA.2012
- Author(s)
  Hitomi Tsuiji
- Organizer
  Cold Spring Harbor Meeting: Neurodegenerative Disorders
- Place of Presentation
  Cold Spring Harbor laboratory, Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Spliceosome Integrity is a Common Target for Motor Neuron Disease2012
- Author(s)
  Hitomi Tsuiji
- Organizer
  第３５回日本神経科学大会
- Place of Presentation
  名古屋国際会議場、名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Integrity fo Spliceosome is a Common Target for Motor Neuron Disease2012
- Author(s)
  Tsuiji H
- Organizer
  第1回国際若手シンポジウム
- Place of Presentation
  京都
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] 運動神経変性疾患に共通するスプライソソーム異常2012
- Author(s)
  築地仁美、井口洋平、古屋亜佐子、片岡礼音、村山繁雄、祖父江元、山中宏二
- Organizer
  第14回RNA学会年会
- Place of Presentation
  仙台(口頭発表)
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] TDP-43 maintains proper U snRNA levels through association with SMN in Cajal/Gem body2012
- Author(s)
  Tsuiji H., Iguchi Y., Furuya A., Kataoka A., Atsuta N., Tanaka F., Sobue G., Yamanaka K
- Organizer
  Keystone Symposia on Molecular and Cellular Biology : Protein-RNA Interaction in Biology and Disease
- Place of Presentation
  Santa Fe, New Mexico/USA
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] TDP-43 in U snRNP regulation2012
- Author(s)
  Tsuiji H., Kataoka A., Yamanaka K.
- Organizer
  Keystone Symposia on Molecular and Cellular Biology: Neurodegenerative Diseases: The Molecular and Cellular Basis for Neurodegeneration (F2)
- Place of Presentation
  Taos, New Mexico, USA
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Spliceosome Integrity is a Common Target for Motor Neuron Disease2012
- Author(s)
  Tsuiji H. and Yamanaka K
- Organizer
  第35回日本神経科学大会シンポジウム : RNA 結合蛋白質と病態
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Spliceosome integrity is defective in motor neuron disease ALS and SMA2012
- Author(s)
  Tsuiji H., Iguchi Y., Furuya A., Kataoka A., Hatsuta H., Atsuta N., Tanaka F., Hashizume Y., Akatsu H., Murayama S., Sobue G., Yamanaka K
- Organizer
  Cold Spring Harbor Meeting : Neurodegenerative Disorders
- Place of Presentation
  Cold Spring Harbor/NY/USA
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] 遺伝性ALS モデルにおけるSIRT1 の関与2012
- Author(s)
  永津真司、築地仁美、木下専、三澤日出巳、山中宏二
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] U snRNP形成における筋萎縮性側索硬化症(ALS)原因遺伝子TDP-43 の役割2011
- Author(s)
  築地仁美、片岡礼音、山中宏二
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(口頭発表)
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] U snRNP形成における筋萎縮性側索硬化症(ALS)原因遺伝子TDP-43の役割2011
- Author(s)
  築地仁美、片岡礼音、山中宏二
- Organizer
  第３４回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] A Role of TDP-43 in Regulation of U snRNP Formation2011
- Author(s)
  Tsuiji H., Kataoka A., Yamanaka K
- Organizer
  Cold Spring Harbor Laboratory Meeting: Eukaryotic mRNA Processing
- Place of Presentation
  Cold Spring Harbor, New York, USA
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] A Role of TDP-43 in The Regulation of spliceosomal U snRNPs2011
- Author(s)
  Tsuiji H., Kataoka A., Yamanaka K.
- Organizer
  The 16th Annual Meeting of the RNA Society and The 13th Annual Meeting of the RNA Society of Japan
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] A Role of TDP-43 in The Regulation of spliceosomal U snRNPs2011
- Author(s)
  Tsuiji H., Kataoka A., Yamanaka K
- Organizer
  The 16^<th> Annual Meeting of the RNA Society and The 13th Annual Meeting of the RNA Society of Japan
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Regulation of spliceosome by ALS-causative gene TDP-432011
- Author(s)
  築地仁美、片岡礼音、山中宏二
- Organizer
  第３４回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] A Role of TDP-43 in Regulation of U snRNP Formation2011
- Author(s)
  Tsuiji H., Kataoka A., Yamanaka K.
- Organizer
  Cold Spring Harbor Laboratory Meeting Eukaryotic mRNA Processing
- Place of Presentation
  Cold Spring Harbor, New York, USA
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Regulation of spliceosome by ALS-causative gene TDP-432011
- Author(s)
  Tsuiji H., Kataoka A., Yamanaka K
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜(口頭発表)
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] 神経特異的mRNA様 non-coding RNAである Gomafu の核内係留メカニズムの解析2008
- Author(s)
  曽根正光, 築地仁美, 甲斐田大輔, 吉田稔, 中川真一
- Organizer
  第10回日本RNA学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19870036
[Presentation] 神経特異的mRNA様non-coding RNAであるGomafuの核内繋留メカニズムの解析2008
- Author(s)
  曽根正光、築地仁美、甲斐田大輔、吉田稔、中川真一
- Organizer
  第10回日本RNA学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19870036
[Presentation] mRNA型ノンコーディングRNAであるGomafuの生化学的性質の検討2007
- Author(s)
  築地仁美、曽根正光、中川真一
- Organizer
  第9回日本RNA学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19870036
[Presentation] mRNA型ノンコーディングRNAであるGomafuの生化学的性質の検討2007
- Author(s)
  築地仁美、曽根正光、中川真一
- Organizer
  第9回日本RNA学会年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19870036
[Presentation] 運動神経変性疾患に共通するスプライソソーム異常
- Author(s)
  築地仁美、井口洋平、古屋亜佐子、片岡礼音、村山繁雄、祖父江元、山中宏二
- Organizer
  第５４回日本神経病理学会総会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] RNA疾患の治療を目指して～筋萎縮性側索硬化症ALSにおけるRNA代謝異常～
- Author(s)
  築地仁美
- Organizer
  東北大学
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Integrity fo Spliceosome is a Common Target for Motor Neuron Disease.
- Author(s)
  Hitomi Tsuiji
- Organizer
  第１回国際若手シンポジウム
- Place of Presentation
  京都平安ホテル、京都
- Data Source
  KAKENHI-PROJECT-23700455
[Presentation] Defects in RNA Metabolism in Neurodegenerative Diseases
- Author(s)
  Hitomi Tsuiji
- Organizer
  スタンフォード大学
- Place of Presentation
  カリフォルニア、米国
- Invited
- Data Source
  KAKENHI-PROJECT-25430055
[Presentation] Region-specific changes in gene expression in transgenic TDP-43 mouse displaying impaired memory
- Author(s)
  Hitomi Tsuiji, Ikuyo Inoue, Asako Furuya, Koji Yamanaka
- Organizer
  The Nineteenth Annual Meeting of the RNA Society
- Place of Presentation
  ケベック、カナダ
- Year and Date
  2014-06-03 – 2014-06-08
- Data Source
  KAKENHI-PROJECT-25430055

1. YAMANAKA Koji (80446533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 内匠透 (00222092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 泊幸秀 (90447368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 森本悟 (00816952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 岡野栄之 (60160694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TANAKA Fumiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 熱田直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 祖父江元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 曽根岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TSUIJI HITOMI 築地 仁美

TSUIJI Hitomi 築地 仁美

Research Projects

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Co-Researchers

Mechanism and application of Hero proteins

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Development of Therapeutic Strategies for Amyotrophic Lateral Sclerosis (ALS) through Modulation of RNA-Binding Protein LevelsPrincipal Investigator

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Elucidation of pathophysiological implications of interneuron degeneration in frontotemporal dementiaPrincipal Investigator

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Common defects of RNA metabolism in motor neuron diseases SMA and ALSPrincipal Investigator

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Defective RNA metabolism in motor neurons from Amyotrophic Lateral Scelosis patientsPrincipal Investigator

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Functional analysis of Gomafu, the mRNA-like non-coding RNAPrincipal Investigator

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[Book] Animal Biotechnology2014

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[Journal Article] dCas13-mediated translational repression for accurate gene silencing in mammalian cells2024

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[Journal Article] The Plasma Membrane Polarity Is Higher in the Neuronal Growth Cone than in the Cell Body of Hippocampal and Cerebellar Granule Neurons2023

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[Journal Article] <i>C9ORF72</i> dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein2021

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[Journal Article] Direct evidence that Ataxin-2 is a translational activator mediating cytoplasmic polyadenylation2020

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[Journal Article] TDP-43 accelerates age-dependent degeneration of interneurons2017

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[Journal Article] Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.2016

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[Journal Article] There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS.2016

Author(s)

TSUIJI HITOMI 築地仁美

TSUIJI Hitomi 築地仁美