Sawaki Taigo 澤城大悟

… Alternative Names

SAWAKI Daigo 澤城大悟

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Researcher Number	40456132
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 自治医科大学, 医学部, 講師 2012: 東京大学, 医学部附属病院, 助教 2011 – 2012: 東京大学, 医学部附属病院, 特任助教 2009 – 2010: The University of Tokyo, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Basic Section 50010:Tumor biology-related / Basic Section 53020:Cardiology-related / 0903:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53020:Cardiology-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator 細胞老化 / 大動脈瘤 / 極性変換 / 腫瘍マクロファージ / 心臓マクロファージ / 極性変化 / HFｐEF / 心筋マクロファージ / 大動脈解離 / ミオシン重鎖 … More / 血管平滑筋 / メカノトランスダクション / 大動脈平滑筋 / 平滑筋ミオシン重鎖 / 大動脈 / TGFβ / 転写因子 / 分子血管病態学 / 心線維化 / 脂肪分化 / レニン・アンギオテンシン / 心血管リモデリング / 病的リモデリング / 代謝心血管相関 / 心血管線維化 … More Except Principal Investigator 心不全 / バイオマーカー / 動脈硬化 / 造血幹細胞 / 老化 / 虚血環境 / 線維芽細胞 / 心臓 / 心臓リモデリング / NADH / 低酸素 / 心線維化 / アミロイドーシス / 質量分析 / メタボローム / 大動脈疾患 / 大動脈解離 Less

マクロファージ細胞老化と極性変化に着目した抗腫瘍治療法の開発Principal Investigator
- Principal Investigator
  
  澤城大悟
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Jichi Medical University
Bone marrow aging and cardiovascular disease
- Principal Investigator
  
  松村貴由
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
NADHを標的とした新たな心臓線維化治療法の開発
- Principal Investigator
  
  砂河孝行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
心筋マクロファージの細胞老化に着目したHFｐEF病態解明と治療法開発Principal Investigator
- Principal Investigator
  
  澤城大悟
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
多次元質量分析による大動脈疾患のメタボロームバイオマーカー解析
- Principal Investigator
  
  冨田翔大
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
プロテオスタシス破綻に基づく心アミロイドーシスの理解と革新的診断法開発
- Principal Investigator
  
  相澤健一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Jichi Medical University
平滑筋ミオシン変異による家族性大動脈解離の分子機構解明と治療法開発Principal Investigator
- Principal Investigator
  
  澤城大悟
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0903:Organ-based internal medicine and related fields
- Research Institution
  Jichi Medical University
KLF6 mediated mechanism as a therapeutic target in aortic diseasesPrincipal Investigator
- Principal Investigator
  
  SAWAKI Daigo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
心血管・代謝疾患における転写因子KLF6を標的とした治療法の開拓Principal Investigator
- Principal Investigator
  
  澤城大悟
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo

All 2023 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Secretory GFP reconstitution labeling of neighboring cells interrogates cell-cell interactions in metastatic niches2023
- Author(s)
  Minegishi M, Kuchimaru T, Nishikawa K, Isagawa Takayuki、Iwano S, Iida K, Hara H, Miura S, Sato M, Watanabe S, Shiomi A, Mabuchi Y, Hamana H, Kishi H, Sato T, Sawaki D, Sato S, Hanazono Y, Suzuki A, Kohro T, Kadonosono T, Shimogori T, Miyawaki, Takeda N, Shintaku H, Kizaka-Kondoh S, Nishimura S
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 8031-8031
- DOI
  10.1038/s41467-023-43855-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-22KJ3140, KAKENHI-PROJECT-22K08110, KAKENHI-PROJECT-23K08994, KAKENHI-PROJECT-19K07273, KAKENHI-ORGANIZER-21H05238, KAKENHI-PLANNED-21H05240, KAKENHI-PROJECT-23K27423
[Journal Article] Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection2023
- Author(s)
  Shota Tomida, Tamaki Ishima, Daigo Sawaki, Yasushi Imai, Ryozo Nagai, Kenichi Aizawa
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 24 Issue: 20 Pages: 15213-15213
- DOI
  10.3390/ijms242015213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22932, KAKENHI-PROJECT-22K20922, KAKENHI-PROJECT-21K08086
[Journal Article] 特集『バイオマーカーupdate -診断から治療評価へ-』「急性大動脈解離」2013
- Author(s)
  澤城大悟、鈴木亨
- Journal Title
  
  ICUとCCU
  
  Volume: vol 37(1) Pages: 21-26
- Data Source
  KAKENHI-PROJECT-23790839
[Journal Article] Targeting Transforming Growth Factor-β Signaling in Aortopathies in Marfan Syndrome2013
- Author(s)
  Sawaki D, Suzuki T
- Journal Title
  
  Circ J
  
  Volume: 77(4) Pages: 898-9
- NAID
  10031138987
- Data Source
  KAKENHI-PROJECT-23790839
[Journal Article] Biomarkers of aortic diseases2013
- Author(s)
  Suzuki T, Bossone E, Sawaki D, Janosi RA, Erbel R, Eagle K, Nagai R.
- Journal Title
  
  Am Heart J
  
  Volume: 165(1) Pages: 15-25
- Data Source
  KAKENHI-PROJECT-23790839
[Journal Article] 循環器病のバイオマーカー2012
- Author(s)
  澤城大悟、鈴木亨
- Journal Title
  
  Heart View
  
  Volume: vol.16 No12(増刊号) Pages: 72-78
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] 低酸素よるミトコンドリアNADHの蓄積は線維芽細胞におけるコラーゲン合成を促進する2023
- Author(s)
  砂河孝行, 澤城大悟, 佐藤達之, 口丸高広, 杉本大樹, 佐藤滋, Ariunbold Chuluun-Erdene, 大野和寿, 興梠貴英, 武田憲彦
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K08110
[Presentation] マルチオミックス解析による家族性大動脈瘤・解離の素因解明：カルシウム輸送経路の障害に起因する大動脈脆弱化2023
- Author(s)
  冨田翔大、石間環、澤城大悟、今井靖、永井良三、相澤健一
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08086
[Presentation] Cardiomyocyte Regulates Cardiac Fibrosis through Cell to Cell Interaction Mediated by KLF62013
- Author(s)
  Daigo Sawaki, Toru Suzuki, Kenichi Aizawa, Takayoshi Matsumura, Yoshiko Munemasa, Junichi Ishida, Scott Friedman, Komuro Issei, Ryozo Nagai
- Organizer
  第77回日本循環器学会総会・学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Regulation of cardiac fibrosis2013
- Author(s)
  澤城大悟
- Organizer
  国際シンポジウム「未解決のがんと心臓病を撲滅する最適医療開発」
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] KLF6 modulates aortic aneurysm formation by regulating both of inflammatory and TGFbeta signaling pathways2013
- Author(s)
  Son BK, Suzuki T, Sawaki D, Aizawa K, Matsumura T, Munemasa Y, Zhan H, Ishida J, Scott Friedman, Komuro Issei, Nagai R
- Organizer
  第77回日本循環器学会総会・学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Cardiomyocyte Regulates Cardiac Fibrosis through Cell to Cell Interaction Mediated by KLF62012
- Author(s)
  Daigo Sawaki, Toru Suzuki, Kenichi Aizawa, Takayoshi Matsumura, Yoshiko Munemasa, Junichi Ishida, Scott Friedman, Ryozo Nagai
- Organizer
  American heart association scientific session 2012
- Place of Presentation
  Los Angeles, CA, USA
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Krüppel-like Factor 6 Modulates Recruitment and Polarization of Inflammatory Cells through Cardiomyocytes in Initiation of Cardiac Fibrosis.2012
- Author(s)
  Daigo Sawaki
- Organizer
  FASEB Summer Research Conference "Biology & Pathobiology of Kruppel-Like Factors (KLFs)"
- Place of Presentation
  Corolado, USA
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Cardiomyocyte Regulates Cardiac Fibrosis through Cell to Cell Interaction Mediated by KLF62012
- Author(s)
  Daigo Sawaki
- Organizer
  American heart association scientific session 2012
- Place of Presentation
  California, USA
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Kruppel-like Factor 6 Modulates Recruitment and Polarization of Inflammatory Cells through Cardiomyocytes in Initiation of Cardiac Fibrosis2012
- Author(s)
  Sawaki D
- Organizer
  FASEB Summer Research Conference "Biology & Pathobiology of Kruppel-Like Factors (KLFs)
- Place of Presentation
  (Snowmass, Colorado, USA
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Aortic remodeling stimulates aneurysm formation in apoE-/- mice through gp130/STAT3 signaling2012
- Author(s)
  Son BK, Suzuki T, Sawaki D, Aizawa K, Matsumura T, Munemasa Y, Zhan H, Okamoto Y, Ishida J, Nagai R
- Organizer
  第76回日本循環器学会総会・学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] KLF6 Modulates Recruitment and Polarization of Inflammatory Cells through Cardiomyocytes in Initiation of Cardiac Fibrosis2012
- Author(s)
  Daigo Sawaki, Toru Suzuki, Kenichi Aizawa, Takayoshi Matsumura, Yoshiko Munemasa, Junichi Ishida, Scott L Friedman, Ryozo Nagai
- Organizer
  第76回日本循環器学会総会・学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Krüppel-like Factor 6 Modulates Initiation of Cardiac Fibrosis2011
- Author(s)
  Daigo Sawaki, Toru Suzuki, Kenichi Aizawa, Takayoshi Matsumura, Yoshiko Munemasa, Junichi Ishida, Scott L Friedman, Ryozo Nagai
- Organizer
  第75回日本循環器学会総会・学術集会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23790839
[Presentation] Kruppel-like Factor 6 Mediates Angiotensin II and TGFβ Signaling in Cardiovascular Pathologies2010
- Author(s)
  澤城大悟
- Organizer
  日本循環器学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-21790705
[Presentation] Kruppel-like Factor 6 Modulates Initiation of Cardiac Fibrosis2010
- Author(s)
  澤城大悟
- Organizer
  2010 FASEB SUMMER RESEARCH CONFEREN CES
- Place of Presentation
  Steamboat Springs, Colorado, U.S.A.
- Year and Date
  2010-08-13
- Data Source
  KAKENHI-PROJECT-21790705

1. 相澤健一 (70436484)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. 木村夏花 (90884453)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 松村貴由 (80436485)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. 冨田翔大 (60784288)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 原田顕治 (10815012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 砂河孝行 (40418637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 岩田洋 (00451807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUZUKI Toru

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. ISHIDA Zyunichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. NAGAI Ryozo

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. 孫輔卿

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岸裕幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sawaki Taigo 澤城 大悟

SAWAKI Daigo 澤城 大悟

Research Projects

Research Products

Co-Researchers

マクロファージ細胞老化と極性変化に着目した抗腫瘍治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bone marrow aging and cardiovascular disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

NADHを標的とした新たな心臓線維化治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心筋マクロファージの細胞老化に着目したHFｐEF病態解明と治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多次元質量分析による大動脈疾患のメタボロームバイオマーカー解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

プロテオスタシス破綻に基づく心アミロイドーシスの理解と革新的診断法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

平滑筋ミオシン変異による家族性大動脈解離の分子機構解明と治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

KLF6 mediated mechanism as a therapeutic target in aortic diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心血管・代謝疾患における転写因子KLF6を標的とした治療法の開拓Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Secretory GFP reconstitution labeling of neighboring cells interrogates cell-cell interactions in metastatic niches2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 特集『バイオマーカーupdate -診断から 治療評価へ-』「急性大動脈解離」2013

Author(s)

Journal Title

Data Source

[Journal Article] Targeting Transforming Growth Factor-β Signaling in Aortopathies in Marfan Syndrome2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Biomarkers of aortic diseases2013

Author(s)

Sawaki Taigo 澤城大悟

SAWAKI Daigo 澤城大悟

[Journal Article] 特集『バイオマーカーupdate -診断から治療評価へ-』「急性大動脈解離」2013

[Presentation] マルチオミックス解析による家族性大動脈瘤・解離の素因解明：カルシウム輸送経路の障害に起因する大動脈脆弱化2023