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Aizawa Kenichi  相澤 健一

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AIZAWA Kenichi  相澤 健一

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Researcher Number 70436484
Other IDs
Affiliation (Current) 2025: 自治医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 自治医科大学, 医学部, 准教授
2013: 東京大学, 医学部附属病院, 助教
2013: 東京大学, 医学部附属病院, 特任助教
2011: 東京大学, 医学部・附属病院, 特任助教
2008 – 2011: The University of Tokyo, 医学部附属病院, 特任助教
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53020:Cardiology-related / Cardiovascular medicine
Except Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 56030:Urology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Cardiovascular medicine … More / Circulatory organs internal medicine / Basic Section 55050:Anesthesiology-related / Basic Section 55020:Digestive surgery-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 49030:Experimental pathology-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Applied pharmacology / Internal medicine of the bio-information integration and related fields / Medical pharmacy Less
Keywords
Principal Investigator
心不全 / 質量分析 / プロテオーム / 蛋白質 / ストレス / 循環器・高血圧 / バイオマーカー / アミロイドーシス / DNA損傷応答 / 転写 … More / 血管老化 / 分子心臓学 / 循環器内科学 / プロテオミクス / 心血管リモデリング / 循環器疾患 / 病態 / 相互作用 / 転写因子 … More
Except Principal Investigator
心不全 / 質量分析 / 大動脈解離 / 癌 / 拒絶反応 / メタボローム解析 / タクロリムス腎症 / メタボローム / 腎移植 / 薬物動態 / 腹膜播種 / 血管 / 家族性大動脈解離 / Myh11 / 応用薬理学 / 立体構造解析 / PDK4 / KLF5阻害薬 / 大腸癌 / 分子創薬 / 蛋白間相互作用阻害薬 / KLF5 / 動脈硬化 / ストレス / プロテオーム / 蛋白質 / 循環器・高血圧 / 3Dイメージング / 空間的トランスクリプトーム解析 / 空間的質量分析 / マルチオミクス解析 / 免疫抑制薬 / 心臓移植 / 癌患者 / 悪性度 / 体液 / がん診断 / 薬物血中濃度 / 網羅的メタボローム解析 / 術後悪心嘔吐 / flowcytometry / 免疫染色 / Claudin18.2 / 胃癌 / フェロトーシス / マルチオミクス / 顕微鏡観察 / 動物モデル / 二光子顕微鏡観察 / 粒子ベース手法 / 内部構造観察 / 動物モデル実験 / 離散モデル / 計算力学 / ラメラ層 / 病態解明 / 早期診断 / 小児肝疾患 / 質量分析イメージング法 / 質量分析イメージング / 網羅歴メタボローム解析 / 胆汁酸分析 / 残余リスク / スタチン / 物質分析イメージング法 / 肝移植後拒絶反応 / 胆汁 / 直接イオン化法 / 免疫逃避 / トロゴサイトーシス / 接着分子 / リンパ球 / がん転移 / トルゴサイトーシス / 大動脈疾患 / バイオマーカー / 心臓マクロファージ / 極性変化 / HFpEF / 細胞老化 / 心筋マクロファージ / 臓器移植 / 腎症 / タクロリムス / Oncocardiology / 癌分子創薬 / アンメットニーズ / 転写因子 / 蛋白間相互作用阻害 / induced helical motif / undruggable / Wntシグナル / 核内因子 / がん分子創薬 / 分子標的薬 / 天然変性蛋白 / 腸内細菌 / 心血管疾患 / バイオマーカ / オミックス / 人工知能 / ビッグデータ / 免疫療法 / 腹腔内投与 / 抗PD-1抗体 / 免疫チェックポイント / フィブロネクチン / 骨髄由来抑制性細胞 / 腫瘍浸潤リンパ球 / 抗PD-1抗体 / 免疫チェックポイント阻害 / 循環器 / Nsd1 / 血管平滑筋細胞 / 形質転換 / 平滑筋細胞 / 血管老化機構 / 平滑筋ミオシン / 先天性心疾患 / 大動脈解離・瘤 / 家族性・遺伝性 / ヒトゲノム解析 / 血管型ミオシン / マルファン症候群 / パネル遺伝子解析 / モデルマウス / Crisper-Cas9 / 動脈管開存 / 臨床遺伝子診断 / 遺伝子改変マウス / 動脈管開存症 / 大動脈瘤 / 臨床薬理学 / 薬剤反応性 / 個別医療 / in silico解析 / 蛋白複合体 / 心‐脳‐腎臓器連関 / 心臓リモデリング / In vivo蛋白複合体解析 / KLF / 心血管リモデリング / トランスレーショナル・リサーチ / トランスレーショナル・リサーチ Less
  • Research Projects

    (35 results)
  • Research Products

    (87 results)
  • Co-Researchers

    (52 People)
  •  腎組織内薬物分布の時空間解析とマルチオミクスを統合したタクロリムス腎症の病態解明

    • Principal Investigator
      岩見 大基
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Jichi Medical University
  •  鉄依存性脂質過酸化の抑制による家族性大動脈瘤・解離の予防・治療法の開発

    • Principal Investigator
      冨田 翔大
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Efficacy of anti-Claudin18.2 antibody for gastric cancer peritoneal dissemination

    • Principal Investigator
      山口 博紀
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jichi Medical University
  •  Posthepatectomy Fentanyl Blood Levels and Comprehensive Metabolome Analysis of PONV Risk Factors

    • Principal Investigator
      竹内 護
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Jichi Medical University
  •  Elucidation of the mechanism of myocardial energy metabolism regulation by NC compound, a KLF5 inhibitor with a beneficial effect on heart failure.

    • Principal Investigator
      永井 良三
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Development of novel cancer diagnosis system using innovative ionization mass spectrometry using body fluid samples

    • Principal Investigator
      佐田 尚宏
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Jichi Medical University
  •  空間マルチオミクス解析と3Dイメージングによる移植心管理の高精度化を目指した研究

    • Principal Investigator
      成田 淳
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  The gut-heart axis as a therapeutic target

    • Principal Investigator
      鈴木 亨
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      The University of Tokyo
  •  多元的質量分析による日本人に特異的なスタチン残余リスクと生成機序解明

    • Principal Investigator
      木村 夏花
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Early Diagnosis and Pathophysiology of Pediatric Liver Disease by Bile Acid Analysis and Mass Spectrometry Imaging

    • Principal Investigator
      佐久間 康成
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Jichi Medical University
  •  動物モデル観察と数値解析による大動脈壁ラメラ層破断の力学機構解明

    • Principal Investigator
      伊井 仁志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Tokyo Metropolitan University
  •  Analysis of the pathogenesis of tacrolimus nephropathy by integrating drug distribution kinetics in renal tissue and metabolomic analysis

    • Principal Investigator
      Iwami Daiki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Jichi Medical University
  •  心筋マクロファージの細胞老化に着目したHFpEF病態解明と治療法開発

    • Principal Investigator
      澤城 大悟
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  多次元質量分析による大動脈疾患のメタボロームバイオマーカー解析

    • Principal Investigator
      冨田 翔大
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Role of trogositosis in tumor immune escape

    • Principal Investigator
      Saito Shin
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Jichi Medical University
  •  プロテオスタシス破綻に基づく心アミロイドーシスの理解と革新的診断法開発Principal Investigator

    • Principal Investigator
      相澤 健一
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Jichi Medical University
  •  肝移植後拒絶反応の病態解明と直接イオン化法による革新的迅速診断法の開発

    • Principal Investigator
      平田 雄大
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Jichi Medical University
  •  Development of intraperitoneal immunotherapy for peritoneal metastasis

    • Principal Investigator
      Yamaguchi Hironori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Jichi Medical University
  •  臨床ビッグデータとトランスオミックス解析を統合した新しい心臓病学パラダイム構築

    • Principal Investigator
      永井 良三
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Jichi Medical University
  •  The mechanism of the transformation of smooth muscle cells in familial thoracic aortic aneurysm and dissection (FTAAD) of point mutation of myosin heavy chain, Myh11,

    • Principal Investigator
      Hayakawa Tomoko
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Development of KLF5 inhibitors that selectively inhibit cancer and improve cardiac function and elucidation of their molecular mechanisms of action

    • Principal Investigator
      Nakaya Takeo
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Jichi Medical University
  •  Molecular mechanism of vascular aging and heart failure due to transcription and DNA damage response and therapeutic applicationPrincipal Investigator

    • Principal Investigator
      Aizawa Kenichi
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  The pathophysiological mechanisms and causative genetic mutations of familial aortic aneusyrm/dissection and patent ductus arteriosus

    • Principal Investigator
      Imai Yasushi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Development of a novel PDK4 inhibitor as a new therapeutic agent for heart failure

    • Principal Investigator
      Nagai Ryozo
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Jichi Medical University
  •  Molecular mechanism of familial aortic dissection by smooth muscle myosin mutation and elucidation of vascular aging mechanism

    • Principal Investigator
      Nagai Ryozo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Development of safety prediction biomarker for drug eluting coronary stent therapy

    • Principal Investigator
      FUJIMURA Akio
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Internal medicine of the bio-information integration and related fields
    • Research Institution
      Jichi Medical University
  •  Elucidation of the mechanism of pathophysiology for precision medicine and development of companion diagnostics

    • Principal Investigator
      SUZUKI Toru
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Jichi Medical University
  •  Basic and clinical research aimed at elucidation of the pathological mechanism of aortic dissection and development of therapeutic methods

    • Principal Investigator
      FUJIMURA Akio
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Jichi Medical University
  •  Elucidation of molecular mechanism and treatment application of heart failure by transcription factor and DNA damage response factorPrincipal Investigator

    • Principal Investigator
      Aizawa Kenichi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Jichi Medical University
  •  Protein complex analysis of transcriptional factor KLF, and development of a low molecular weight compound that inhibits KLF5 transcriptional activity.

    • Principal Investigator
      Nagai Ryozo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Jichi Medical University
  •  Improvement of the PDK4 inhibitors based on the tertiary structure analysis and application for the treatment of heart failure

    • Principal Investigator
      Nagai Ryozo
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Jichi Medical University
  •  Elucidation of cardiovascular pathologies by regulating the processing of the peptide

    • Principal Investigator
      SUZUKI Toru
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Elucidation of the cardiovascular disease by the innovative three-dimensional proteome analytical method

    • Principal Investigator
      SUZUKI Toru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Elucidation of a new mechanism of the cardiovascular pathologies by novel physiologically activity substance identified by proteomic analysisPrincipal Investigator

    • Principal Investigator
      AIZAWA Kenichi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Elucidation of the mechanism of caediovascular remodeling and development of therapy by proteomic analysisPrincipal Investigator

    • Principal Investigator
      AIZAWA Kenichi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2020 2019 2018 2016 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

  • [Book] バイオマーカーの探索・発見・同定の試(5.今後のバイオマーカーの展望,特集:循環器病のバイオマーカー企画・構成/井上晃男)2012

    • Author(s)
      相澤健一,鈴木亨
    • Publisher
      Heart View
    • Data Source
      KAKENHI-PROJECT-24659383
  • [Book] バイオマーカーの探索・発見・同定の試(5.今後のバイオマーカーの展望, 特集 : 循環器病のバイオマーカー企画・構成/井上晃男)2012

    • Author(s)
      相澤健一, 鈴木亨
    • Publisher
      Heart View
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Book] 新しい動脈硬化のバイオマーカー開発 : 新しいプロテオーム技術を用いて(3.動脈硬化のバイオマーカーの臨床的意義, <特集>第76回日本循環器学会学術集会). 循環器専門医 : 日本循環器学会専門医誌2012

    • Author(s)
      相澤健一, 鈴木亨
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Book] 新しい動脈硬化のバイオマーカー開発:新しいプロテオーム技術を用いて(3.動脈硬化のバイオマーカーの臨床的意義,<特集>第76回日本循環器学会学術集会) 循環器専門医:日本循環器学会専門医誌2012

    • Author(s)
      相澤健一,鈴木亨
    • Data Source
      KAKENHI-PROJECT-24659383
  • [Book] 心血管マルチバイオマーカー・ストラテジー2009

    • Author(s)
      相澤健一、鈴木亨
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] Metabolomic Profiling of Mice with Tacrolimus-Induced Nephrotoxicity: Carnitine Deficiency in Renal Tissue2024

    • Author(s)
      Nishida Sho、Ishima Tamaki、Kimura Natsuka、Iwami Daiki、Nagai Ryozo、Imai Yasushi、Aizawa Kenichi
    • Journal Title

      Biomedicines

      Volume: 12 Issue: 3 Pages: 521-521

    • DOI

      10.3390/biomedicines12030521

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H03069
  • [Journal Article] Peptide mimetic <scp>NC114</scp> induces growth arrest by preventing <scp>PKCδ</scp> activation and <scp>FOXM1</scp> nuclear translocation in colorectal cancer cells2024

    • Author(s)
      Taguchi Yuki、Nakaya Takeo、Aizawa Kenichi、Noguchi Yoshiyuki、Maiya Nobuhiko、Iwamoto Chisako、Ohba Kenichi、Sugawara Minoru、Murata Masayuki、Nagai Ryozo、Kano Fumi
    • Journal Title

      FEBS Open Bio

      Volume: 14 Issue: 4 Pages: 695-720

    • DOI

      10.1002/2211-5463.13784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07512
  • [Journal Article] Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection2023

    • Author(s)
      Shota Tomida, Tamaki Ishima, Daigo Sawaki, Yasushi Imai, Ryozo Nagai, Kenichi Aizawa
    • Journal Title

      International Journal of Molecular Science

      Volume: 24 Issue: 20 Pages: 15213-15213

    • DOI

      10.3390/ijms242015213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K22932, KAKENHI-PROJECT-22K20922, KAKENHI-PROJECT-21K08086
  • [Journal Article] Novel Drug Delivery Method Targeting Para-Aortic Lymph Nodes by Retrograde Infusion of Paclitaxel into Pigs’ Thoracic Duct2022

    • Author(s)
      Saito Akira、Kimura Natsuka、Kaneda Yuji、Ohzawa Hideyuki、Miyato Hideyo、Yamaguchi Hironori、Lefor Alan Kawarai、Nagai Ryozo、Sata Naohiro、Kitayama Joji、Aizawa Kenichi
    • Journal Title

      Cancers

      Volume: 14 Issue: 15 Pages: 3753-3753

    • DOI

      10.3390/cancers14153753

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08989
  • [Journal Article] An Myh11 single lysine deletion causes aortic dissection by reducing aortic structural integrity and contractility2022

    • Author(s)
      Negishi Keita、Aizawa Kenichi、Shindo Takayuki、Suzuki Toru、Sakurai Takayuki、Saito Yuichiro、Miyakawa Takuya、Tanokura Masaru、Kataoka Yosky、Maeda Mitsuyo、Tomida Shota、Morita Hiroyuki、Takeda Norifumi、Komuro Issei、Kario Kazuomi、Nagai Ryozo、Imai Yasushi
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 1-14

    • DOI

      10.1038/s41598-022-12418-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02811
  • [Journal Article] Development of Low-Molecular-Weight Compounds Targeting the Cancer-Associated KLF5 Transcription Factor2022

    • Author(s)
      Takeo Nakaya, Kenichi Aizawa, Yuki Taguchi, Kentaro Tsuji, Sachi Sekine, Kazuhiro Murakami, Masaji Kasai, Hirofumi Nakano, Yasumitsu Kondoh, Shingo Dan, Atsushi Yoshimori, Hiroyuki Kouji, Dai Takehara, Toru Suzuki, Hiroyuki Osada, Masayuki Murata, Akira Tanaka, and Ryozo Nagai
    • Journal Title

      ACS Med. Chem. Lett.

      Volume: 13 Issue: 4 Pages: 687-694

    • DOI

      10.1021/acsmedchemlett.1c00721

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07512, KAKENHI-PROJECT-19K16777
  • [Journal Article] Ethnic differences in association of outcomes with trimethylamine N‐oxide in acute heart failure patients2020

    • Author(s)
      Yazaki Yoshiyuki、Aizawa Kenichi、Israr Muhammad Zubair、Negishi Keita、Salzano Andrea、Saitoh Yuka、Kimura Natsuka、Kono Ken、Heaney Liam、Cassambai Shabana、Bernieh Dennis、Lai Florence、Imai Yasushi、Kario Kazuomi、Nagai Ryozo、Ng Leong L.、Suzuki Toru
    • Journal Title

      ESC Heart Failure

      Volume: 7 Issue: 5 Pages: 2373-2378

    • DOI

      10.1002/ehf2.12777

    • Data Source
      KAKENHI-PROJECT-18K08083
  • [Journal Article] Indomethacin reduces rates of aortic dissection and rupture of the abdominal aorta by inhibiting monocyte/macrophage accumulation in a murine model2019

    • Author(s)
      Tomida S, Aizawa K, Nishida N, Aoki H, Imai Y, Nagai R, Suzuki T.
    • Journal Title

      Sci Rep

      Volume: 24 Issue: 1 Pages: 10751-10751

    • DOI

      10.1038/s41598-019-46673-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08083
  • [Journal Article] 循環器臨床におけるプロテオミクスの現状と将来展望2018

    • Author(s)
      相澤健一
    • Journal Title

      Precision Medicine

      Volume: 1 Pages: 136-139

    • Data Source
      KAKENHI-PROJECT-18K08046
  • [Journal Article] 循環器臨床におけるプロテオミクスの現状と将来展望2018

    • Author(s)
      相澤健一
    • Journal Title

      Precision Medicine

      Volume: 1 Pages: 136-139

    • Data Source
      KAKENHI-PROJECT-15K09145
  • [Journal Article] Ataxia telangiectasia mutated in cardiac fibroblasts regulates doxorubicin-induced cardiotoxicity2016

    • Author(s)
      Zhan H, Aizawa K, Sun JQ, Tomida S, Otsu K, Conway S, McKinnon P, Manabe I, Komuro I, Miyagawa K, Nagai R, Suzuki T
    • Journal Title

      Cardiovasc. Res.

      Volume: 110 Issue: 1 Pages: 85-95

    • DOI

      10.1093/cvr/cvw032

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09145, KAKENHI-PROJECT-15H04824
  • [Journal Article] Processed B-Type Natriuretic Peptide Is a Biomarker of Postinterventional Restenosis in Ischemic Heart Disease2013

    • Author(s)
      Fujimoto H, Suzuki T, Aizawa K, Sawaki D, Ishida J, Ando J, Fujita H, Komuro I, Nagai R
    • Journal Title

      Clin Chem

      Volume: 59 Pages: 1330-1337

    • Data Source
      KAKENHI-PROJECT-23390204
  • [Journal Article] Inverse correlations between serum ADAMTS13 levels and systolic blood pressure, pulse pressure, and serum C-reactive protein levels observed at a general health examination in a Japanese population : a cross-sectional study2013

    • Author(s)
      Enokoku K, Ikeda H, Kato R, Kume Y, Yoshida H, Ono T, Aizawa K, Suzuki T, Yamzaki T, Yatomi Y
    • Journal Title

      Clin. Chim. Acta

      Volume: 421 Pages: 147-151

    • Data Source
      KAKENHI-PROJECT-23390204
  • [Journal Article] Inverse correlations between serum ADAMTS13 levels and systolic blood pressure, pulse pressure, and serum C-reactive protein levels observed at a general health examination in a Japanese population: A cross-sectional study2013

    • Author(s)
      Enooku K
    • Journal Title

      Clin Chim Acta

      Volume: 421C Pages: 147-151

    • DOI

      10.1016/j.cca.2013.03.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249017, KAKENHI-PROJECT-23390204, KAKENHI-PROJECT-24659383
  • [Journal Article] Takotsubo Cardiomyopathy: Japanese Perspective.2013

    • Author(s)
      Aizawa K, Suzuki T.
    • Journal Title

      Heart Failure Clin.

      Volume: 9 Issue: 2 Pages: 243-247

    • DOI

      10.1016/j.hfc.2012.12.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390204, KAKENHI-PROJECT-24659383
  • [Journal Article] Processed B-Type Natriuretic Peptide Is a Biomarker of Postinterventional Restenosis in Ischemic Heart Disease2013

    • Author(s)
      Fujimoto H, Suzuki T, Aizawa K, Sawaki D, Ishida J, Ando J, Fujita H, Komuro I, Nagai R.
    • Journal Title

      Clin Chem

      Volume: 59 Pages: 1330-1337

    • Data Source
      KAKENHI-PROJECT-24659383
  • [Journal Article] Inverse correlations between serum ADAMTS13 levels and systolic blood pressure, pulse pressure, and serum C-reactive protein levels observed at a general health examination in a Japanese population : a cross-sectional study2013

    • Author(s)
      Enokoku K, Ikeda H, Kato R, Kume Y, Yoshida H, Ono T, Aizawa K, Suzuki T, Yamzaki T, Yatomi Y.
    • Journal Title

      Clin. Chim. Acta

      Volume: 421 Pages: 147-151

    • Data Source
      KAKENHI-PROJECT-24659383
  • [Journal Article] Processed B-Type Natriuretic Peptide Is a Biomarker of Postinterventional Restenosis in Ischemic Heart Disease.2013

    • Author(s)
      Fujimoto H, Suzuki T, Aizawa K, Sawaki D, Ishida J, Ando J, Fujita H, Komuro I, Nagai R.
    • Journal Title

      Clin Chem.

      Volume: 59 Issue: 9 Pages: 1330-1337

    • DOI

      10.1373/clinchem.2013.203406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390204, KAKENHI-PROJECT-24659383
  • [Journal Article] Sawaki D, Nagai R. Comparison of Analytical Performance of Two Single-step Measurement Devices of B-type Natriuretic Peptide2012

    • Author(s)
      Ishida J, Suzuki T, Aizawa K, Sawaki D, Nagai R
    • Journal Title

      Int Heart J

      Volume: 53 Pages: 320-3

    • Data Source
      KAKENHI-PROJECT-23390204
  • [Journal Article] Comparison of Analytical Performance of Two Single-step Measurement Devices of B-type Natriuretic Peptide2012

    • Author(s)
      Ishida J, Suzuki T, Aizawa K, Sawaki D, Nagai R.
    • Journal Title

      Int Heart J

      Volume: 53 Pages: 320-3

    • NAID

      130001914169

    • Data Source
      KAKENHI-PROJECT-24659383
  • [Journal Article] Ataxia telangiectasia mutated(ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence2010

    • Author(s)
      Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R
    • Journal Title

      Journal of Biological Chemistry

      Volume: 285 Pages: 29662-29670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Journal Article] Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.2010

    • Author(s)
      Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 29662-29670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Journal Article] Kruppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct stimulation of cell growth and inhibition of apoptosis2009

    • Author(s)
      Suzuki T, Sawaki D, Aizawa K, Munemasa Y, Matsumura T, Ishida J, Nagai R
    • Journal Title

      J Biol Chem 284

      Pages: 9549-9557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] Regulation of transforming growth factor-b-dependent cyclooxygenase-2 expression in fibroblasts.2009

    • Author(s)
      Matsumura T, Suzuki T, Aizawa K, Sawaki D, Munemasa Y, Ishida J, Nagai R.
    • Journal Title

      Journal of Biological Chemistry. 284

      Pages: 35861-35871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] Regulation of transforming growth factor-R-dependent cyclooxygenase-2 expression in fibroblasts2009

    • Author(s)
      Matsumura T, Suzuki T, Aizawa K, Sawaki D, Munemasa Y, Ishida J, Nagai R
    • Journal Title

      J Biol Chem 284

      Pages: 35861-35871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] Kruppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct stimulation of cell growth and inhibition of apoptosis.2009

    • Author(s)
      Suzuki T, Sawaki D, Aizawa K, Munemasa Y, Matsumura T, Ishida J, Nagai R
    • Journal Title

      Journal of Biological Chemistry. 284

      Pages: 9549-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] 変性蛋白の測定2009

    • Author(s)
      相澤健一、鈴木亨
    • Journal Title

      呼吸と循環 57

      Pages: 723-728

    • NAID

      40016717472

    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] 心血管病の診断と治療におけるバイオマーカーの有用性2009

    • Author(s)
      相澤健一、 鈴木亨
    • Journal Title

      Mebio 26

      Pages: 104-110

    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] 心血管病態のプロテオミクス解析2008

    • Author(s)
      相澤健一、鈴木亨
    • Journal Title

      循環器専門医

      Pages: 43-49

    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] Acyclic retinoid inhibits functional interaction of transcription factors Kruppel-like factor 5 and retinoic acid receptor-alpha.2008

    • Author(s)
      Kada N, Suzuki T, Aizawa K, Munemasa Y, Matsumura T, Sawaki D, Nagai R
    • Journal Title

      FEBS Lett. 582

      Pages: 1755-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] Promotor region-specific histone incorporation by the novel histone chaperone ANP32B and DNA-binding factor KLF5.2008

    • Author(s)
      Munemasa Y, Suzuki T, Aizawa K, Miyamoto S, Imai Y, MatsumuraT, Horikoshi M, Nagai R
    • Journal Title

      Molecular and Cellular Biology 28

      Pages: 1171-1181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] Acyclic retinoid inhibits functional interaction of transcription factors Kruppel-like factor 5 and retinoic acid receptor-alpha2008

    • Author(s)
      Kada N, Suzuki T, Aizawa K, Munemasa Y, Matsumura T, Sawaki D, Nagai R
    • Journal Title

      FEBS Lett. 582

      Pages: 1755-1760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Journal Article] 心血管病態のプロテオミクス解析2008

    • Author(s)
      相澤健一、鈴木亨
    • Journal Title

      循環器専門医 16

      Pages: 43-49

    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] マルチオミックス解析による家族性大動脈瘤・解離の素因解明:カルシウム輸送経路の障害に 起因する大動脈脆弱化2023

    • Author(s)
      冨田翔大、石間環、澤城大悟、今井靖、永井良三、相澤健一
    • Organizer
      第44回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08086
  • [Presentation] A novel mouse model of familial thoracic aortic aneurysms and dissections with a deletion mutation in Myh112019

    • Author(s)
      根岸経太、相澤健一、今井靖、永井良三
    • Organizer
      第40回日本臨床薬理学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08083
  • [Presentation] A Deletion Mutation in Myosin Heavy Chain MYH11 Reduces the Contraction Force of the Aorta Resulting in Aortic Dissection2019

    • Author(s)
      Negishi K, Aizawa K, Imai Y et al.
    • Organizer
      第83回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08083
  • [Presentation] レチノイン酸受容体結合因子であるNsd1は血管平滑筋細胞の形質転換を制御する2019

    • Author(s)
      早川朋子、今井利美、相澤健一、今井靖、永井良三、真鍋一郎
    • Organizer
      第40回 日本臨床薬理学会
    • Data Source
      KAKENHI-PROJECT-19K08548
  • [Presentation] A deletion mutation in myosin heavy chain MYH11 reduces the contraction force of the aorta resulting in aortic dissection2019

    • Author(s)
      Keita Negishi, Kenichi Aizawa, Takayuki Shindo, Yuichiro Saito, Toru Suzuki, Kazuomi Kario, Ryozo Nagai, Yasushi Imai
    • Organizer
      第83回日本循環器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02811
  • [Presentation] Processed B-type natriuretic peptide measured by immuno-mass spectrometry is a biomarker of post-interventional restenosis in ischemic heart disease2014

    • Author(s)
      Kenichi Aizawa, Toru Suzuki, Hirotaka Fujimoto,Daigo Sawaki, Junichi Ishida, Jiro Ando, Hideo Fujita, Ryozo Nagai, Issei Komuro
    • Organizer
      第78回日本循環器学会総会・学術集会
    • Place of Presentation
      幕張メッセ国際展示場
    • Data Source
      KAKENHI-PROJECT-24659383
  • [Presentation] Processed B-type natriuretic peptide measured by immuno-mass spectrometry is a biomarker of post-interventional restenosis in ischemic heart disease2014

    • Author(s)
      Kenichi Aizawa, Toru Suzuki, Hirotaka Fujimoto,Daigo Sawaki, Junichi Ishida, Jiro Ando, Hideo Fujita, Ryozo Nagai, Issei Komuro
    • Organizer
      第78回日本循環器学会総会・学術集会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Presentation] Processed B-type natriuretic peptide measured by immuno-mass spectrometry is a biomarker of postinterventional restenosis in ischemic heart disease2013

    • Author(s)
      Aizawa K, Suzuki T, Fujimoto H, Sawaki D, Ishida J, Ando J, Fujita H, Nagai R, Komuro I.
    • Organizer
      第78回日本循環器学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659383
  • [Presentation] プロセシングを受けたB型ナトリウム利尿ペプチドは、虚血性心疾患における心臓カテーテル治療後再狭窄のバイオマーカーである2013

    • Author(s)
      相澤健一、鈴木亨、藤本宏隆、澤城大悟、石田純一、安東治郎、藤田英雄、小室一成、永井良三
    • Organizer
      第38回日本医用マススペクトル学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-09-26
    • Data Source
      KAKENHI-PROJECT-24659383
  • [Presentation] Processed B-type natriuretic peptide measured by immuno-mass spectrometry is a biomarker of postinterventional restenosis in ischemic heart disease2013

    • Author(s)
      Aizawa K, Suzuki T, Fujimoto H, Sawaki D, Ishida J, Ando J, Fujita H, Nagai R, Komuro I
    • Organizer
      第78回日本循環器学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Presentation] プロセシングを受けたB型ナトリウム利尿ペプチドは, 虚血性心疾患における心臓カテーテル治療後再狭窄のバイオマーカーである2013

    • Author(s)
      相澤健一, 鈴木亨, 藤本宏隆, 澤城大悟, 石田純一, 安東治郎, 藤田英雄, 小室一成, 永井良三
    • Organizer
      第38回日本医用マススペクトル学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-09-26
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Presentation] Processed B-type natriuretic peptide is a biomarker of post-interventional restenosis in ischemic heart disease2013

    • Author(s)
      Aizawa K, Suzuki T, Fujimoto H, Sawaki D, Ishida J, Ando J, Fujita H, Komuro I, Nagai R
    • Organizer
      HUPO 12th Annual World Congress
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Presentation] Processed B-type natriuretic peptide is a biomarker of post-interventional restenosis in ischemic heart disease2013

    • Author(s)
      Aizawa K, Suzuki T, Fujimoto H, Sawaki D, Ishida J, Ando J, Fujita H, Komuro I, Nagai R.
    • Organizer
      HUPO 12th Annual World Congress
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-24659383
  • [Presentation] Histone H2AX is Important in the Regulation of Cardiac Hypertrophy2013

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Sawaki D, Ishida J, Komuro I, Nagai R.
    • Organizer
      第77回日本循環器学会総会・学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659383
  • [Presentation] Kruppel-like factor 6(KLF6) exacerbates glucose intolerance and obesity2012

    • Author(s)
      Ishida J, Suzuki T, Aizawa K, Sawaki D, Matsumura T, Friedman SL, Nagai R
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Regulation of cardiac hypertrophy by DNA damage response as mediated by KLF52012

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Sawaki D, Ishida J, Nagai R
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cells senescence2012

    • Author(s)
      Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Aortic remodeling stimulates aneurysm formation in apoE-/-mice through gp130/STAT3 signaling2012

    • Author(s)
      Son BK, Suzuki T, Sawaki D, Aizawa K, Matsumura T, Munemasa Y, Zhan H, Okamoto Y, Ishida J, Nagai R
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Telangiectasia Mutated(ATM)-mediated DNA Damage Response Regulates Doxorubicin-induced Cardiotoxicity2012

    • Author(s)
      Zhan H, Suzuki T, Aizawa K, Sawaki D, Ishida J, Miyagawa K, Nagai R. Ataxia
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Ataxia Telangiectasia Mutated (ATM)-mediated DNA Damage Response Regulates Doxorubicin-induced Cardiotoxicity2012

    • Author(s)
      Zhan H, Suzuki T, Aizawa K, Sawaki D, Ishida J, Miyagawa K, Nagai R
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] KLF6 Modulates Recruitment and Polarization of Inflammatory Cells through Cardiomyocytes in Initiation of Cardiac Fibrosis2012

    • Author(s)
      Sawaki D, Suzuki T, Aizawa K, Matsumura T, Munemasa Y, Ishida J, Friedman SL^<2)>, Nagai R
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Kruppel-like Factor 6(KLF6) is Involved in Glucose Intolerance and Obesity2011

    • Author(s)
      Ishida J, Suzuki T, Aizawa K, Sawaki D, Matsumura T, Friedman SL, Nagai R
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] DNA damage response is important in the regulation of cardiac hypertrophy2011

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Sawaki D, Ishida J, Mastumura T, Nagai R
    • Organizer
      American Heart Association, Scientific Session 2011
    • Place of Presentation
      オーランド(米国)
    • Year and Date
      2011-11-16
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] プロセスされたB型ナトリウム利尿ホルモンは冠動脈疾患における経皮的冠動脈インターベンション後再狭窄のマーカーである2011

    • Author(s)
      藤本宏隆, 鈴木亨, 相澤健一, 澤城大悟, 石田純一, 永井良三
    • Organizer
      第36回日本医用マススペクトル学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Presentation] PROCESSED B-TYPE NATRIURETIC PEPTIDE IS A BIOMAEKER OF POST-INTERVENTIONAL RESTENOSIS IN ISCHEMIC HEART DISEASE2011

    • Author(s)
      H.Fujimoto, T.Suzuki, K.Aizawa, D.Sawaki, J.Ishida, R.Nagai
    • Organizer
      HUPO 2011 10th Annual World Congress
    • Place of Presentation
      ジュネーブ(スイス)
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Presentation] Ataxiatelangiectasia mutated (ATM)-mediated DNA damage response in oxidativestress-induced vascular endothelial cells senescence2011

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Miyagawa K, Nagai R
    • Organizer
      2011 Gordon Research Conferences ; Mammalian DNA Repair
    • Place of Presentation
      Ventura, CA, USA
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Ataxiatelangiectasia mutated(ATM)-mediated DNA damage response in oxidativestress-induced vascular endothelial cells senescence2011

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Miyagawa K, Nagai R
    • Organizer
      2011 Gordon Research Conferences ; Mammalian DNA Repair
    • Place of Presentation
      Ventura, CA, USA
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Kruppel-like Factor 6 modulates initiation of cardiac fibrosis. 2010 FASEB Summer Research Conferences2011

    • Author(s)
      Sawaki D, Suzuki T, Aizawa K, Matsumura T, Munemasa Y, Ishida J, Friedman SL, Nagai R
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2011-08-03
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Processed B-type natriuretic peptide is a biomarker of post-interventional restenosis in ischemic heart disease2011

    • Author(s)
      Fujimoto H, Suzuki T, Aizawa K, Sawaki D, Ishida J, Nagai R
    • Organizer
      HUPO 201110TH World Congress
    • Place of Presentation
      Geneva, Swiss Confederation
    • Year and Date
      2011-09-04
    • Data Source
      KAKENHI-PROJECT-23390204
  • [Presentation] Ataxia telangiectasia mutated(ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cells senescence2011

    • Author(s)
      Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Kruppel-like factor 6(KLF6) is involved in adiposity2010

    • Author(s)
      Ishida J, Suzuki T, Aizawa K, Sawaki D, Matsumura T, Friedman SL, Nagai R
    • Organizer
      2010 FASEB Summer Research Conferences
    • Place of Presentation
      Steamboat Springs, CO, USA
    • Year and Date
      2010-08-11
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Ataxia telangiectasia mutated mediates oxidative stress-induced premature cell senescence in vacular endothelial cells. 16th International vascular Biology Meeting2010

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Matsumura T, Sawaki D, Ishida J, Miyagawa K, Nagai R
    • Organizer
      16th International vascular Biology Meeting
    • Place of Presentation
      Los Angeles, CA, USA
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Identification of a new regulatory pathway of pathologic vascular injury as mediated by KLF5 by proteome analysis2010

    • Author(s)
      Aizawa K, Suzuki T, Matsumura T, Sawaki D, Ishida J, Nagai
    • Organizer
      2010 FASEB Summer Research Conferences
    • Place of Presentation
      Steamboat Springs, CO, USA
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Kruppel-like Factor 6 modulates initiation of cardiac fibrosis2010

    • Author(s)
      Sawaki D, Suzuki T, Aizawa K, Matsumura T, Munemasa Y, Ishida J, Friedman SL, Nagai R
    • Organizer
      2010 FASEB Summer Research Conferences
    • Place of Presentation
      Steamboat Springs, CO, USA
    • Year and Date
      2010-08-12
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] Ataxia telangiectasia mutated mediates oxidative stress-induced premature cell senescence in vacular endothelial cells2010

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Matsumura T, Sawaki D, Ishida J, Miyagawa K, Nagai R
    • Organizer
      16th International vascular Biology Meeting
    • Place of Presentation
      Los Angeles, CA, USA
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] 心血管病態におけるプロテオミクス解析法を用いた新規シグナル伝達経路の同定2010

    • Author(s)
      相澤健一、鈴木亨、永井良三
    • Organizer
      第58回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22790692
  • [Presentation] 抗oxLDL抗体を用いた免沈回収産物の迅速プロファイリング. 日本ヒトプロテオーム機構2008

    • Author(s)
      宮崎賢司、田伏洋、寺本礼仁、藤田真知子、服部渉、川浦久雄、宗政歓子、村松貴由、相澤健一、永井良三、鈴木亨
    • Organizer
      第6回大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] Proteome analysis of a novel pathogenic pathway of DNA damage response as mediated by KLF5 and its transcriptional complexes in the cardiovasculature2008

    • Author(s)
      Aizawa K, Suzuki T, Zhan H, Kada N, Sawaki D, Matsumura T, Nagai R
    • Organizer
      15th International Vascular Biology Meeting
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-06-02
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] 等電点電気泳動チップによる翻訳後等電点電気泳動チップによる翻訳後修飾されたタンパク質の検出.2008

    • Author(s)
      田伏洋、宮崎賢司、寺本礼仁、藤田真知子、服部渉、川浦久雄、宗政歓子、村松貴由、相澤健一、永井良三、鈴木亨
    • Organizer
      第6回大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] A novel pathogenic pathway of DNA damage response as mediated by KLF5 and its transcriptional complexes in the cardiovasculature.2008

    • Author(s)
      Aizawa K, Suzuki T, Hong A, Kada N, Sawaki D, Matsumura T, Nagai R
    • Organizer
      第72回日本循環器学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] Angiotensin II activates the DNA damage response through nitric oxide in vascular endothelial cells.2007

    • Author(s)
      Aizawa K, Suzuki T, MatsumuraT, Sawaki D, Kada N, Nagai R.
    • Organizer
      第71回日本循環器学会総会・学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] Modulation of ubiquitin-proteasomal degradation of KLF5 influences vascular remodeling.2007

    • Author(s)
      Sawaki D, Suzuki T, Aizawa K, Matsumura T, Kada N, Mizuno Y, Munemasa Y, Nagai R
    • Organizer
      第71回日本循環器学会総会・学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] Acyclic retinoid inhibits neointima formation through retinoic acid receptor beta-induced apoptosis.2007

    • Author(s)
      Kada N, Suzuki T, Aizawa K, Matsumura T, Takeda N, Sawaki D, Nagai R
    • Organizer
      第71回日本循環器学会総会・学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] A novel regulatory pathway of DNA damage response to pathologic vascular injury as mediated by KLF5 and its transcriptional complexes.2007

    • Author(s)
      Aizawa K, Suzuki T, Matsumura T, Sawaki D, Kada N, Nagai R
    • Organizer
      第71回日本循環器学会総会・学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] 非環式レチノイドはRARbetaを介してアポトーシスを生じ新生内膜形成を抑制する.2007

    • Author(s)
      加田奈々絵、鈴木亨、相澤健一、松村貴由、澤城大悟、宗政歓子、永井良三
    • Organizer
      東京大学臨床展開研究シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-03-02
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] Kruppel-like factor 5 promotes vascular remodeling in biphasic ways; inhibition of vascular smooth muscle cell (VSMC) apoptosis and stimulation of cell growth.2007

    • Author(s)
      Sawaki D, Suzuki T, Aizawa K, Matsumura T, Kada N, Mizuno Y, Munemasa Y, Nagai R
    • Organizer
      American Heart Association 80th Scientific Sessions
    • Place of Presentation
      Orlando, FL, USA
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] Proteome analysis of a regulatory pathway of pathologic vascular injury as mediated by KLF5 and its transcriptional complexes.2007

    • Author(s)
      Aizawa K, Suzuki T, Matsumura T, Kada N, Sawaki D, Zhan H, Nagai R
    • Organizer
      American Heart Association, Scientific Session 2007
    • Place of Presentation
      Orlando, Florida, U.S.
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] 新規ヒストンシャペロンp32と転写因子KLF5によるプロモーター領域特異的ヒストン量増加. Promoter region-specific histone incorporation by histone chaperone p32 and DNA-binding factor KLF5.2007

    • Author(s)
      宗政歓子、鈴木亨、相澤健一、宮本索、今井靖、松村貴由、水野由子、加田奈々枝、澤城大悟、永井良三
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790519
  • [Presentation] Kruppel-like factor 5 directly stimulates cell growth in vascular lesions.2007

    • Author(s)
      Sawaki D, Suzuki T, Aizawa K, Matsumura T, Kada N, Mizuno Y, Munemasa Y, Nagai R
    • Organizer
      第71回日本循環器学会総会・学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20790519
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