YASHIRO KENTA 八代健太

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Yashiro Kenta 八代健太

八代健太ヤシロケンタ

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Researcher Number	60432506
Other IDs
Affiliation (Current)	2022: 京都府立医科大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2018 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2018: 大阪大学, 医学系研究科, 招へい教授 2017: 大阪大学, 医学系研究科, 特任准教授(常勤) 2007: Osaka University, 大学院・生命機能研究科, 助教
Review Section/Research Field	Principal Investigator General medical chemistry / Biomedical structure and function and related fields / Pediatrics / Complex systems / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 48010:Anatomy-related
Keywords	Principal Investigator 分化 / 循環器 / 発生・分化 / 解剖学 / 心臓前駆細胞 / 細胞間相互作用 / シングルセル解析 / 発生生物学 / 形態形成学 / 神経病態生化学 … More / レチノイン酸代謝 / マウス / DiGeorge症候群 / 原腸陥入 / 精子形成 / 左心室心筋 / 右心室心筋 / 生物学的な相違 / 左右心室心筋 / 相違 / 遺伝子発現プロファイル / 蛋白発現プロファイル / 力学特性 / Tbx5 / プロテオーム / 心筋緻密化 / GFRA2 / シグナル経路 / リガンド / 新規シグナル経路 / 心筋緻密化障害 / 心臓発生 / 心筋分化 / 臨床遺伝学 / ゲノム編集 / ヒトゲノム研究 / 再生医学 / 遺伝学 / GFRA1/2新規シグナル経路 / 心室大血管関係 / Pitx2 / 流出路 / 新規バイオマーカー / 転写制御 … More Except Principal Investigator 心臓 / 形態形成 / 分化運命 / 転写制御 Less

心室筋細胞特異的な分化運命決定および転写制御機構の解明
- Principal Investigator
  
  渡邉裕介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  National Cardiovascular Center Research Institute
Cellular Society to Regulate The Anatomical Alignment between Heart Ventricles and Outflow Tracts.Principal Investigator
- Principal Investigator
  
  八代健太
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto Prefectural University of Medicine
The Study of Molecular Mechanism to Establish Cardiac Progenitor's IdentityPrincipal Investigator
- Principal Investigator
  
  八代健太
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Are left ventricular cardiomyocytes intrincically different from right ventricular ones?Principal Investigator
- Principal Investigator
  
  Yashiro Kenta
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical structure and function and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
  Osaka University
The Study of Pathophysiological Role of GFRA2, GPI-anchored plasma Membrane Protein, for Left Ventricular Non-Compaction CardiomyopathyPrincipal Investigator
- Principal Investigator
  
  Yashiro Kenta
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
  Osaka University
レチノイン酸代謝酵素CYP26が胚発生と成体中枢神経機能において果たす役割の解析Principal Investigator
- Principal Investigator
  
  八代健太
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University

All 2020 2019 2018 2017 2007

All Journal Article Presentation

[Journal Article] 心筋分化とiPS細胞研究2020
- Author(s)
  八代　健太
- Journal Title
  
  日本小児科学会雑誌
  
  Volume: 124 Pages: 509-519
- Data Source
  KAKENHI-PROJECT-17H04228
[Journal Article] 心筋分化とiPS 細胞研究2020
- Author(s)
  八代健太
- Journal Title
  
  日本小児科学会雑誌
  
  Volume: 124 Pages: 509-519
- Data Source
  KAKENHI-PROJECT-17K19523
[Journal Article] 左室心筋と右室心筋は何が違うのか2019
- Author(s)
  八代健太
- Journal Title
  
  実験医学増刊「心不全のサイエンス」
  
  Volume: 37 Pages: 204-211
- Data Source
  KAKENHI-PROJECT-17H04228
[Journal Article] Sox17 expression in endocardium precursor cells regulates heart development in mice2019
- Author(s)
  Rie Saba, Keiko Kitajima, Lucille Rainbow, Sylvia Engert, Mami Uemura, Hidekazu Ishida, Ioannis Kokkinopoulos, Yasunori Shintani, Shigeru Miyagawa, Yoshiakira Kanai, Masami Kanai-Azuma, Peter Koopman, Chikara Meno, John Kenny, Heiko Lickert, Yumiko Saga, Ken Suzuki, Yoshiki Sawa, Kenta Yashiro.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/548289
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19523, KAKENHI-PROJECT-17H04228
[Journal Article] Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.2019
- Author(s)
  Saba Rie、Kitajima Keiko、Rainbow Lucille、Engert Silvia、Uemura Mami、Ishida Hidekazu、Kokkinopoulos Ioannis、Shintani Yasunori、Miyagawa Shigeru、Kanai Yoshiakira、Kanai-Azuma Masami、Koopman Peter、Meno Chikara、Kenny John、Lickert Heiko、Saga Yumiko、Suzuki Ken、Sawa Yoshiki、Yashiro Kenta
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Pages: 11953-11953
- DOI
  10.1038/s41598-019-48321-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-17H01571, KAKENHI-PROJECT-17H04228, KAKENHI-PROJECT-17K19523
[Journal Article] 左室心筋と右室心筋は何が違うのか2019
- Author(s)
  八代健太
- Journal Title
  
  実験医学増刊　心不全のサイエンス
  
  Volume: 35 Pages: 204-211
- Data Source
  KAKENHI-PROJECT-17K19523
[Journal Article] A Lesson From the Thalidomide Tragedy　― <i>The Past Is Never Dead. It’s Not Even Past.</i> William Faulkner, From “<i>Requiem for a Nun</i>” ―2018
- Author(s)
  Kenta Yashiro, Shigeru Miyagawa, and Yoshiki Sawa.
- Journal Title
  
  Circulation Journal
  
  Volume: 82 Issue: 9 Pages: 2250-2252
- DOI
  10.1253/circj.cj-18-0775
  10.1253/circj.CJ-18-0775
- NAID
  130007438918
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19523, KAKENHI-PROJECT-17H04228
[Journal Article] Molecular Mechanism Underlying Heterotaxy and Cardiac Isomerism2017
- Author(s)
  Yashiro Kenta、Miyagawa Shigeru、Sawa Yoshiki
- Journal Title
  
  Ped Cardiol Card Surg
  
  Volume: 33 Issue: 5 Pages: 349-361
- DOI
  10.9794/jspccs.33.349
- NAID
  130006195231
- ISSN
  0911-1794, 2187-2988
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19523, KAKENHI-PROJECT-17H04228
[Journal Article] 特集心臓の発生･再生･創生 Ⅰ.心臓の発生と進化左右軸の分子機構と心臓形成2017
- Author(s)
  八代健太、宮川繁、澤芳樹
- Journal Title
  
  生体の科学
  
  Volume: 68 Issue: 6 Pages: 520-524
- DOI
  10.11477/mf.2425200722
- ISSN
  0370-9531, 1883-5503
- Data Source
  KAKENHI-PROJECT-17K19523, KAKENHI-PROJECT-17H04228
[Journal Article] Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins2017
- Author(s)
  Bridge Katherine S.、Shah Kunal M.、Li Yigen、Foxler Daniel E.、Wong Sybil C.K.、Miller Duncan C.、Davidson Kathryn M.、Foster John G.、Rose Ruth、Hodgkinson Michael R.、Ribeiro Paulo S.、Aboobaker A. Aziz、Yashiro Kenta、Wang Xiaozhong、Graves Paul R.、Plevin Michael J.、Lagos Dimitris、Sharp Tyson V.
- Journal Title
  
  Cell Reports
  
  Volume: 20 Pages: 173-187
- DOI
  10.1016/j.celrep.2017.06.027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19523, KAKENHI-PROJECT-17H04228
[Journal Article] Haemodynamics determined by the genetic programme govern asymmetric development of the aortic arch2007
- Author(s)
  Yashiro K, Shiratori H, and Hamada H
- Journal Title
  
  Nature Vol.450
  
  Pages: 285-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590277
[Journal Article] CYP26Al and CYP26Cl cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse2007
- Author(s)
  Uehara M, Yashiro K, Mamiya S, Nishino J, Chambon P, Dolle P and Sakai Y
- Journal Title
  
  Developmental Biology 302巻・2号
  
  Pages: 399-411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590277
[Presentation] 心室中隔の発生～どこからどのように形成されるのか？～2019
- Author(s)
  八代健太
- Organizer
  第５５回日本小児循環器学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] 心筋分化とiPS細胞研究2019
- Author(s)
  八代健太
- Organizer
  第１２２回日本小児科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] シングルセル解析から見えてきた心臓前駆細胞の姿2019
- Author(s)
  八代健太
- Organizer
  第125回日本解剖学会総会・全国学術集会（COVID-19により紙面開催）
- Invited
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] シングルセル解析から見えてきた心臓前駆細胞の姿2019
- Author(s)
  八代健太
- Organizer
  第 125 回日本解剖学会総会・全国学術集会（COVID-19のために紙面開催）
- Invited
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] 心筋分化とiPS細胞研究2019
- Author(s)
  八代健太
- Organizer
  第１２２回日本小児科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞での発現と心臓形態形成における機能2019
- Author(s)
  八代健太
- Organizer
  第124回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] 心室中隔の発生～どこからどのように形成されるのか？～2019
- Author(s)
  八代健太
- Organizer
  第５５回日本小児循環器学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞での発現と心臓形態形成における機能2019
- Author(s)
  八代健太
- Organizer
  第124回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] SoxF class transcription factor Sox17 identifies endocardium progenitor cells and regulates the heart development in mice.2018
- Author(s)
  Yashiro, K., Saba, R., Ishida, H., Kanai, Y., Meno, C., Koopman, P., Lickert, H., Saga, Y., Miyagawa, S., Suzuki, K., and Sawa, Y.
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] SoxF class transcription factor Sox17 identifies endocardium progenitor cells and regulates the heart development in mice2018
- Author(s)
  Yashiro, K., Saba, R., Ishida, H., Kanai, Y., Meno, C., Koopman, P., Lickert, H., Saga, Y., Miyagawa, S., Suzuki, K., and Sawa, Y.
- Organizer
  American Heart Association scientific Sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞の分化と心臓発生に果たす役割2018
- Author(s)
  八代健太, 佐波理恵, 石田秀和, 小垣滋豊, 宮川繁, 大薗恵一, 鈴木憲, 澤芳樹
- Organizer
  第54回日本小児循環器学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞の分化と心臓発生に果たす役割2018
- Author(s)
  八代健太, 佐波理恵, 石田秀和, 小垣滋豊, 宮川繁, 大薗恵一, 鈴木憲, 澤芳樹
- Organizer
  第54回日本小児循環器学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] SoxF class transcription factor Sox17 identifies endocardium progenitor cells and regulates the heart development in mice.2018
- Author(s)
  Yashiro, K., Saba, R., Ishida, H., Kanai, Y., Meno, C., Koopman, P., Lickert, H., Saga, Y., Miyagawa, S., Suzuki, K., and Sawa, Y.
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] SoxF class transcription factor Sox17 identifies endocardium progenitor cells and regulates the heart development in mice2018
- Author(s)
  Yashiro, K., Saba, R., Ishida, H., Kanai, Y., Meno, C., Koopman, P., Lickert, H., Saga, Y., Miyagawa, S., Suzuki, K., and Sawa, Y.
- Organizer
  American Heart Association scientific Sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] Glycosylphosphatidylinositol-anchor containing neurotrophic factor receptor GFRA2 identifies cardiac progenitors and mediates cardiomyocyte differentiation via an alternative signal pathway.2017
- Author(s)
  Hidekazu Ishida, Rie Saba, Ioannis Kokkinopoulos, Yasushi Sakata, Leo Dunkel, Andrew Tinker, Anna-Katerina Hadjantonakis, Yoshiki Sawa, Hiroshi Sasaki, Keiichi Ozono, Ken Suzuki, and Kenta Yashiro
- Organizer
  Takao International Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] Glycosylphosphatidylinositol-anchor containing neurotrophic factor receptor GFRA2 identifies cardiac progenitors and mediates cardiomyocyte differentiation via an alternative signal pathway.2017
- Author(s)
  Hidekazu Ishida, Rie Saba, Ioannis Kokkinopoulos, Yasushi Sakata, Leo Dunkel, Andrew Tinker, Anna-Katerina Hadjantonakis, Yoshiki Sawa, Hiroshi Sasaki, Keiichi Ozono, Ken Suzuki, and Kenta Yashiro
- Organizer
  Takao International Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] Glycosylphosphatidylinositol-anchor containing neurotrophic factor receptor GFRA2 identifies cardiac progenitors and mediates cardiomyocyte differentiation via an alternative signal pathway.2017
- Author(s)
  Hidekazu Ishida, Rie Saba, Ioannis Kokkinopoulos, Yasushi Sakata, Leo Dunkel, Andrew Tinker, Anna-Katerina Hadjantonakis, Yoshiki Sawa, Hiroshi Sasaki, Keiichi Ozono, Ken Suzuki, and Kenta Yashiro
- Organizer
  Weinstein Cardiovascular Development and Regeneration Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] 単一細胞遺伝子発現プロファイリングより見えてきた心臓発生の分子機構2017
- Author(s)
  八代健太
- Organizer
  第120回日本小児科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] Glycosylphosphatidylinositol-anchor containing neurotrophic factor receptor GFRA2 identifies cardiac progenitors and mediates cardiomyocyte differentiation via an alternative signal pathway.2017
- Author(s)
  Kenta Yashiro
- Organizer
  CDB symposium 2017 “Towards Understanding Human Development, Heredity, and Evolution”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] 単一細胞遺伝子発現プロファイリングより見えてきた心臓発生の分子機構2017
- Author(s)
  八代健太
- Organizer
  第120回日本小児科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] Glycosylphosphatidylinositol-anchor containing neurotrophic factor receptor GFRA2 identifies cardiac progenitors and mediates cardiomyocyte differentiation via an alternative signal pathway.2017
- Author(s)
  Kenta Yashiro
- Organizer
  CDB symposium 2017 “Towards Understanding Human Development, Heredity, and Evolution”
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] 単一細胞遺伝子発現プロファイルより見えてきた心臓前駆細胞の新知見.2017
- Author(s)
  八代健太
- Organizer
  生命科学系学会合同年次大会（第40回日本分子生物学会年会, 第90回日本生化学会大会）
- Invited
- Data Source
  KAKENHI-PROJECT-17H04228
[Presentation] 単一細胞遺伝子発現プロファイルより見えてきた心臓前駆細胞の新知見.2017
- Author(s)
  八代健太
- Organizer
  生命科学系学会合同年次大会（第40回日本分子生物学会年会, 第90回日本生化学会大会）
- Invited
- Data Source
  KAKENHI-PROJECT-17K19523
[Presentation] Glycosylphosphatidylinositol-anchor containing neurotrophic factor receptor GFRA2 identifies cardiac progenitors and mediates cardiomyocyte differentiation via an alternative signal pathway.2017
- Author(s)
  Hidekazu Ishida, Rie Saba, Ioannis Kokkinopoulos, Yasushi Sakata, Leo Dunkel, Andrew Tinker, Anna-Katerina Hadjantonakis, Yoshiki Sawa, Hiroshi Sasaki, Keiichi Ozono, Ken Suzuki, and Kenta Yashiro
- Organizer
  Weinstein Cardiovascular Development and Regeneration Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04228

1. 渡邉裕介 (20562333)

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2. 中川修 (40283593)

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3. 垣花優希 (40910534)

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4. 橋本大輝 (40911342)

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5. 原田恭弘 (70911402)

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6. LAMRI LYNDA (90883984)

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7. 新谷泰範

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8. 目野主税

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YASHIRO KENTA 八代 健太

Yashiro Kenta 八代 健太

八代 健太 ヤシロ ケンタ

Research Projects

Research Products

Co-Researchers

心室筋細胞特異的な分化運命決定および転写制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cellular Society to Regulate The Anatomical Alignment between Heart Ventricles and Outflow Tracts.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Study of Molecular Mechanism to Establish Cardiac Progenitor's IdentityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Are left ventricular cardiomyocytes intrincically different from right ventricular ones?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Study of Pathophysiological Role of GFRA2, GPI-anchored plasma Membrane Protein, for Left Ventricular Non-Compaction CardiomyopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

レチノイン酸代謝酵素CYP26が胚発生と成体中枢神経機能において果たす役割の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 心筋分化とiPS細胞研究2020

Author(s)

Journal Title

Data Source

[Journal Article] 心筋分化とiPS 細胞研究2020

Author(s)

Journal Title

Data Source

[Journal Article] 左室心筋と右室心筋は何が違うのか2019

Author(s)

Journal Title

Data Source

[Journal Article] Sox17 expression in endocardium precursor cells regulates heart development in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 左室心筋と右室心筋は何が違うのか2019

Author(s)

Journal Title

Data Source

[Journal Article] A Lesson From the Thalidomide Tragedy ― <i>The Past Is Never Dead. It’s Not Even Past.</i> William Faulkner, From “<i>Requiem for a Nun</i>” ―2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Molecular Mechanism Underlying Heterotaxy and Cardiac Isomerism2017

Author(s)

Journal Title

DOI

YASHIRO KENTA 八代健太

Yashiro Kenta 八代健太

八代健太ヤシロケンタ

[Journal Article] A Lesson From the Thalidomide Tragedy　― <i>The Past Is Never Dead. It’s Not Even Past.</i> William Faulkner, From “<i>Requiem for a Nun</i>” ―2018

[Journal Article] 特集心臓の発生･再生･創生 Ⅰ.心臓の発生と進化左右軸の分子機構と心臓形成2017

[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞での発現と心臓形態形成における機能2019

[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞での発現と心臓形態形成における機能2019

[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞の分化と心臓発生に果たす役割2018

[Presentation] Sry関連HMG-box転写因子Sox17が心内膜前駆細胞の分化と心臓発生に果たす役割2018