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Malay Ali  Malay Ali

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… Alternative Names

MALAY Ali  マレイ アリ

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Researcher Number 40467006
Other IDs
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 上級研究員
Affiliation (based on the past Project Information) *help 2025: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 上級研究員
2023: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 上席研究員
2022: 東京工業大学, 物質理工学院, 研究員
2021: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 上級研究員
2015: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員
2013 – 2014: 独立行政法人理化学研究所, Heddle国際主幹研究ユニット, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 43020:Structural biochemistry-related / Biomedical engineering/Biomaterial science and engineering
Except Principal Investigator
Medium-sized Section 35:Polymers, organic materials, and related fields
Keywords
Principal Investigator
self-assembly / silk protein / biochemistry / biomaterial / spider / phase separation / biomimetics / nanofibril / coacervate / fibrous protein … More / biomimetic / biomolecular condensate / liquid phase separation / biopolymer / silk / protein shell / protein structure / drug delivery / cryo EM / gold catalysis / synthetic biology / protein / coordination chemistry / protein engineering / capsid / self assembly / gold chemistry / gold cluster / supramolecular assembly / smart nanomaterial / artificial capsid / metal coordination / gold nanoparticle / bionanotechnology / protein cage … More
Except Principal Investigator
シルク Less
  • Research Projects

    (3 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (3 People)
  •  クモ牽引糸タンパク質の分子機構を明らかにし、クモ糸の階層構造を人工的に再現する

    • Principal Investigator
      沼田 圭司
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 35:Polymers, organic materials, and related fields
    • Research Institution
      Kyoto University
  •  Investigating spider silk self-assembly via liquid-liquid phase separationPrincipal Investigator

    • Principal Investigator
      Malay Ali
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Institute of Physical and Chemical Research
      Tokyo Institute of Technology
  •  Exploring the structure and mechanism of formation of an artificial protein capsid, toward the development of a novel redox-responsive nano-carrier systemPrincipal Investigator

    • Principal Investigator
      Malay Ali
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Replicating shear-mediated self-assembly of spider silk through microfluidics2024

    • Author(s)
      Jianming Chen, Arata Tsuchida, Ali D. Malay, Kousuke Tsuchiya, Hiroyasu Masunaga, Yui Tsuji, Mako Kuzumoto, Kenji Urayama, Hirofumi Shintaku & Keiji Numata
    • Journal Title

      Nature Communications

      Volume: 15 Issue: 1 Pages: 527-527

    • DOI

      10.1038/s41467-024-44733-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Journal Article] Unusual pKa Values Mediate the Self-Assembly of Spider Dragline Silk Proteins2023

    • Author(s)
      Oktaviani Nur Alia、Malay Ali D.、Matsugami Akimasa、Hayashi Fumiaki、Numata Keiji
    • Journal Title

      Biomacromolecules

      Volume: 24 Issue: 4 Pages: 1604-1616

    • DOI

      10.1021/acs.biomac.2c01344

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043, KAKENHI-PROJECT-20K15738
  • [Journal Article] NMR assignment and dynamics of the dimeric form of soluble C-terminal domain major ampullate spidroin 2 from Latrodectus hesperus2023

    • Author(s)
      NA Oktaviani, AD Malay, M Goto, T Nagashima, F Hayashi, K Numata
    • Journal Title

      Biomolecular NMR Assignments

      Volume: 17 Issue: 2 Pages: 249-255

    • DOI

      10.1007/s12104-023-10150-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Journal Article] 1000 spider silkomes: Linking sequences to silk physical properties2022

    • Author(s)
      Arakawa Kazuharu、Kono Nobuaki、Malay Ali D.、Tateishi Ayaka、Ifuku Nao、et al.
    • Journal Title

      Science Advances

      Volume: 8 Issue: 41 Pages: 6043-6043

    • DOI

      10.1126/sciadv.abo6043

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043, KAKENHI-PROJECT-20K15738
  • [Journal Article] Complexity of spider dragline silk2022

    • Author(s)
      Malay AD, Craig HC, Chen J, Oktaviani NA, Numata K
    • Journal Title

      Biomacromolecules

      Volume: 23 Issue: 5 Pages: 1827-1840

    • DOI

      10.1021/acs.biomac.1c01682

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Journal Article] A silk composite fiber reinforced by telechelic-type polyalanine and its strengthening mechanism2022

    • Author(s)
      Chen J, Tsuchiya K, Masunaga H, Malay AD, Numata K
    • Journal Title

      Polymer Chemistry

      Volume: 13 Issue: 13 Pages: 1869-1879

    • DOI

      10.1039/d2py00030j

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Journal Article] Micrometer‐Scale Optical Web Made of Spider Dragline Fibers with Optical Gate Operations2022

    • Author(s)
      Hendra、Yamagishi Hiroshi、Heah Wey Yih、Malay Ali D.、Numata Keiji、Yamamoto Yohei
    • Journal Title

      Advanced Optical Materials

      Volume: (none) Issue: 13 Pages: 2202563-2202563

    • DOI

      10.1002/adom.202202563

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Journal Article] Multicomponent nature underlies the extraordinary mechanical properties of spider dragline silk2021

    • Author(s)
      Kono N, Nakamura H, Mori M, Yoshida Y, Ohtoshi R, Malay AD, Moran DAP, Tomita M, Numata K, Arakawa K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 118 Issue: 31

    • DOI

      10.1073/pnas.2107065118

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043, KAKENHI-PROJECT-23K21203
  • [Journal Article] Darwin's bark spider shares a spidroin repertoire with Caerostris extrusa but achieves extraordinary silk toughness through gene expression.2021

    • Author(s)
      Kono N, Ohtoshi R, Malay AD, Mori M, Masunaga H, Yoshida Y, Nakamura H, Numata K, Arakawa K
    • Journal Title

      Open Biology

      Volume: 11 Issue: 12 Pages: 210242-210242

    • DOI

      10.1098/rsob.210242

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043, KAKENHI-PROJECT-23K21203
  • [Journal Article] Probing structural dynamics of an artificial protein cage using high-speedatomic force microscopy2015

    • Author(s)
      M. Imamura, T. Uchihashi, T. Ando, A. Leifert, U. Simon, A. D. Malay and J. G. Heddle
    • Journal Title

      Nano Letters

      Volume: 15 Issue: 2 Pages: 1331-1335

    • DOI

      10.1021/nl5045617

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23115008, KAKENHI-PROJECT-24227005, KAKENHI-PROJECT-24241048, KAKENHI-PROJECT-25560231, KAKENHI-PUBLICLY-26102515, KAKENHI-PUBLICLY-26104514, KAKENHI-PROJECT-26600052
  • [Presentation] Probing rapid self-assembly of MaSp1 from soluble protein to hierarchical fiber2023

    • Author(s)
      Ali D. Malay
    • Organizer
      Gordon Research Conference: Silk Proteins and the Transition to Biotechnologies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Presentation] Probing rapid self-assembly of MaSp1 from soluble protein to hierarchical fiber2023

    • Author(s)
      Ali D. Malay, Keiji Numata
    • Organizer
      繊維学会「地球に優しい繊維材料研究委員会2023年度シンポジウム」
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Presentation] Exploring the self-assembly of MaSp1 dragline silk spidroin into native-like hierarchical fibers2022

    • Author(s)
      Malay, Ali D.
    • Organizer
      71st Symposium on Macromolecules and the Society Polymer Science
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Presentation] Dissecting the molecular basis for liquid-liquid phase separation of spider silk proteins during self-assembly2022

    • Author(s)
      Malay, Ali D.
    • Organizer
      ERATO Numata Organellar Reaction Cluster Project Symposium
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Presentation] Biomimetic self-assembly of spider silk via liquid-liquid phase separation2022

    • Author(s)
      Malay, Ali D.
    • Organizer
      Annual Meeting of the Society of Fiber Science and Technology
    • Data Source
      KAKENHI-PROJECT-21K06043
  • [Presentation] Bio-nanotechnology: engineering a redox-responsive supramolecular protein cage structure for drug delivery2014

    • Author(s)
      Ali Malay
    • Organizer
      University of the Philippines, College of Medicine
    • Place of Presentation
      Manila, Philippines
    • Year and Date
      2014-12-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-25560231
  • [Presentation] Development of a nano-delivery system based on an engineered protein cage structure

    • Author(s)
      Ali Malay
    • Organizer
      Asia-Pacific International Molecular Biology Network (A-IMBN) 17th Annual Conference
    • Place of Presentation
      Manila, Philippines
    • Year and Date
      2014-12-01 – 2014-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-25560231
  • 1.  沼田 圭司 (40584529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  増永 啓康 (50398468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  内橋 貴之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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