Popiel Helena Akiko ポピエルヘレナ・明子

… Alternative Names

POPIEL HELENA Akiko ポピエルヘレナ明子

ポピエルヘレナ・アキコポピエルヘレナ・アキコ

POPIEL Helena Akiko ポピエルヘレナ明子

POPIE HELENA Akiko ポピエルヘレナ明子

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Researcher Number	40467593
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2013 – 2015: 東京医科大学, 医学部, 助教 2012: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第四部, 科研費研究員 2011 – 2012: 独立行政法人国立精神・神経医療研究センター, 神経研究所・疾病研究第四部, 科研費研究員 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所・疾病研究第四部, 科研費研究員 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第四部, 科研費研究員 … More 2010: (独)国立精神・神経医療研究センター, 神経研究所疾病研究第四部, 流動研究員 2010: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第四部, 流動研究員 2009: 国立精神・神経センター, 流動研究員 2009: National Center of Neurology and Psychiatry, 神経研究所疾病研究第四部, 流動研究員 2009: National Center of Neurology and Psychiatry, 神経研究所疾病研究第四部, 流動研究員 2008: National Center of Neurology and Psychiatry, 神経研究所・疾病研究第四部, 外来研究員 2008: 国立精神・神経センター, 神経研究所疾病研究第四部, 外来研究員 Less
Review Section/Research Field	Principal Investigator Neurology / Neurochemistry/Neuropharmacology Except Principal Investigator Biological Sciences / Neurology
Keywords	Principal Investigator ポリグルタミン病 / 神経変性疾患 / オリゴマー / 脳神経疾患 / 治療薬開発 / バイオテクノロジー / 薬剤スクリーニング / 蛋白質 / アミロイド / コンフォメーション伝播 … More / バイオマーカー / ポルグルタミン病 / 凝集阻害 / 創薬 / 血液脳関門 / ドラッグデリバリー / 神経科学 … More Except Principal Investigator ポリグルタミン病 / 神経変性疾患 / 脳神経疾患 / 神経科学 / アミロイド / 蛋白質 / 分子シャペロン / プリオン / 感染 / スクリーニング / 治療薬 / QBP1 / オリゴマー / βシート / 遣伝子 / ショウジョウバエ / ストレス / 遺伝子 Less

Establishment of a molecular therapy for the polyglutamine diseases targeting toxic oligomersPrincipal Investigator
- Principal Investigator
  
  Popiel Helena Akiko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Medical University
  独立行政法人国立精神・神経医療研究センター
アミロイド性タンパク質凝集体の細胞間・個体間の伝播・感染メカニズムの解明
- Principal Investigator
  
  永井義隆
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Center of Neurology and Psychiatry
Therapy for the polyglutamine diseases via selection of oligomer inhibitors using new technologies SPR & FCSPrincipal Investigator
- Principal Investigator
  
  POPIEL HELENA Akiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry
Demonstration of the abnormal conformational transition of amyloid proteins and it's application as an early diagnostic toolPrincipal Investigator
- Principal Investigator
  
  POPIEL HELENA Akiko
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry
ミスフォールディング病に対する内在性分子シャペロン発現誘導による治療法開発
- Principal Investigator
  
  NAGAI Yoshitaka
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Center of Neurology and Psychiatry
Molecular therapy for the polyglutamine diseases targeting the toxic β-sheet conformers and oligomers
- Principal Investigator
  
  NAGAI Yoshitaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry
Molecular therapy for the polyglutamine diseases using a novel brain delivery method of aggregate inhibitor peptidesPrincipal Investigator
- Principal Investigator
  
  POPIE HELENA Akiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center of Neurology and Psychiatry

All 2015 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] p62 plays a protective role in the autophagic degradation of polyglutamine protein oligomers in polyglutamine disease model flies.2015
- Author(s)
  Saitoh Y, Fujikake N, Okamoto Y, Popiel HA, Hatanaka Y, Ueyama M, Suzuki M, Gaumer S, Murata M, Wada K, Nagai Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 3 Pages: 1442-53
- DOI
  10.1074/jbc.m114.590281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591286, KAKENHI-PROJECT-24591287, KAKENHI-PUBLICLY-25110741, KAKENHI-PROJECT-25860733, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-15K09331
[Journal Article] Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level.2015
- Author(s)
  Takeuchi T, Suzuki M, Fujikake N, Popiel HA, Kikuchi H, Futaki S, Wada K, Nagai Y
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: in press Issue: 19
- DOI
  10.1073/pnas.1412651112
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25110741, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-24591287, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-26713030
[Journal Article] Peptide-Based Therapeutic Approaches for Treatment of the Polyglutamine Diseases2014
- Author(s)
  Takeuchi T, Popiel HA, Futaki S, Wada K, Nagai Y
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591287
[Journal Article] Inhibition of protein misfolding/aggregation using polyglutamine binding peptide QBP1 as a therapy for the polyglutamine diseases2013
- Author(s)
  Popiel HA, Takeuchi T, Burke JR, Strittmatter WJ, Toda T, Wada K, Nagai Y
- Journal Title
  
  Neurotherapeutics
  
  Volume: (in press)
- URL
  http://link.springer.com/article/10.1007%2Fs13311-013-0184-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200072
[Journal Article] Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases.2013
- Author(s)
  H. Akiko Popiel
- Journal Title
  
  Neuro therapeutics
  
  Volume: (印刷中) Issue: 3 Pages: 440-446
- DOI
  10.1007/s13311-013-0184-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08829, KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-23249049, KAKENHI-PROJECT-23390237, KAKENHI-PROJECT-24591287, KAKENHI-PROJECT-24659438, KAKENHI-PUBLICLY-25110741, KAKENHI-PROJECT-25882021, KAKENHI-PUBLICLY-23110528
[Journal Article] Hsp40 Gene Therapy Exerts Therapeutic Effects on Polyglutamine Disease Micevia a Non-Cell Autonomous Mechanism.2012
- Author(s)
  H. Akiko Popiel
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 11 Pages: e51069-e51069
- DOI
  10.1371/journal.pone.0051069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08829, KAKENHI-PROJECT-21200072, KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-23249049, KAKENHI-PROJECT-23390237, KAKENHI-PROJECT-23590473, KAKENHI-PROJECT-24591287, KAKENHI-PROJECT-24659438, KAKENHI-PUBLICLY-23110515, KAKENHI-PUBLICLY-23110528
[Journal Article] The aggregation inhibitor peptide QBP1 as a therapeutic molecule for the polyglutamine neurodegenerative diseases2011
- Author(s)
  H.Akiko Popiel
- Journal Title
  
  Journal of Atnino Acids
  
  Volume: 2011 Pages: 265084-265084
- DOI
  10.4061/2011/265084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08829, KAKENHI-PROJECT-21200072, KAKENHI-PUBLICLY-22020038, KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-22659172, KAKENHI-PROJECT-22790837, KAKENHI-PUBLICLY-23110528, KAKENHI-PROJECT-23249049, KAKENHI-PROJECT-23390237
[Journal Article] Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases.2010
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Wada K
- Journal Title
  
  Current Pharrnaceutical Biotechnology 11
  
  Pages: 188-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Journal Article] Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases.2010
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Wada K
- Journal Title
  
  Current Pharmaceutical Biotechnology 11
  
  Pages: 188-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200072
[Journal Article] Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases2010
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Wada K
- Journal Title
  
  Curr Pharm Biotechnol
  
  Volume: 11 Pages: 188-197
- URL
  http://www.eurekaselect.com/71304/article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200072
[Journal Article] Genetic Testing for Huntington's Disease in Parkinsonism2010
- Author(s)
  Rahman MS, Nagai Y, Popiel HA, Fujikake N, Okamoto Y, Ahmed MU, Islam MA, Islam MT, Ahmed S, Rahman KM, Uddin MJ, Dey SK, Ahmed Q, Hossain MA, Jahan N, Toda T
- Journal Title
  
  Mymensingh Med J 19(4)
  
  Pages: 510-514
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases2010
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Wada K
- Journal Title
  
  Curr. Pharm. Biotech. 11
  
  Pages: 188-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Journal Article] Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases2010
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Wada K
- Journal Title
  
  Current Pharmaceutical Biotechnology 11
  
  Pages: 188-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Structure-activity relationship study on polyglutamine binding peptide QBP12010
- Author(s)
  Tomita K, Popiel HA, Nagai Y, Ohno H, Oishi S, Fujii N
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 188-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Journal Article] Genetic testing for Huntington's disease in Parkinsonism2010
- Author(s)
  Rahman MS, Nagai Y, Popiel HA, Fujikake N, Okamoto Y, Ahmed MU, Islam MA, Islam MT, Ahmed S, Rahman KM, Uddin MJ, Dey SK, Ahmed Q, Hossain MA, Jahan N, Toda T
- Journal Title
  
  Mymensingh Med J
  
  Volume: 19 Pages: 510-514
- URL
  http://www.banglajol.info/index.php/MMJ/article/view/6708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200072
[Journal Article] Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases2010
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Wada K
- Journal Title
  
  Curr Pharm Biotechnol 11(2)
  
  Pages: 188-197
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Genetic testing for Huntington's disease in Parkinsonism2010
- Author(s)
  Rahman MS, Nagai Y, Popiel HA, Fujikake N, Okamoto Y, Ahmed MU, Islam MA, Islam MT, Ahmed S, Rahman KM, Uddin MJ, Dey SK, Ahmed Q, Hossain MA, Jahan N, Toda T
- Journal Title
  
  Mymensingh Med. J
  
  Volume: 19 Pages: 510-514
- URL
  http://www.banglajol.info/index.php/MMJ/article/view/6708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790837
[Journal Article] Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases.2010
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Wada K
- Journal Title
  
  Current Pharmaceutical Biotechnology 11
  
  Pages: 188-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20059023
[Journal Article] Delivery of the aggregate inhibitor peptide QBP1 into the mouse brain using PTDs and its therapeutic effects on polyglutamine disease mice2009
- Author(s)
  Popiel, H.A.
- Journal Title
  
  Neurosci. Lett. 449(2)
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Journal Article] 脊髄小脳変性症-What's new?「遺伝子治療」2009
- Author(s)
  永井義隆、ポピエル明子
- Journal Title
  
  Clinical Neuroscience 27(1)
  
  Pages: 95-98
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Delivery of the aggregate inhibitor peptide QBP1 into the mouse brain using PTDs and its therapeutic effects on polyglutamine disease mice2009
- Author(s)
  Popiel, H.A.
- Journal Title
  
  Neurosci. Lett. 449(2)
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20059023
[Journal Article] Delivery of the aggregate inhibitor peptide QBP1 into the mouse brain using PTDs and its therapeutic effects on polyglutamine disease mice2009
- Author(s)
  Popiel, H. A.
- Journal Title
  
  Neurosci. Lett. 449(2)
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Delivery of the aggregate inhibitor peptide QBP1 into the mouse brain using PTDs and its therapeutic effects on polyglutamine disease mice2009
- Author(s)
  Popiel HA, Nagai Y, Fujikake N, Toda T
- Journal Title
  
  Neurosci Lett 449(2)
  
  Pages: 87-92
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Structure-activity relationship study on polyglutamine binding peptide QBP12009
- Author(s)
  Tomita K, Popiel HA, Nagai Y, Toda T, Yoshimitsu Y, Ohno H, Oishi S, Fujii N
- Journal Title
  
  Bioorg Med Chem 17(3)
  
  Pages: 1259-1263
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Surface plasmon resonance characterization of specific binding of polyglutamine aggregate inhibitors to the expanded polyglutamine stretch2009
- Author(s)
  Okamoto Y, Nagai Y, Fujikake N, Popiel HA, Yoshioka T, Toda T, Inui T
- Journal Title
  
  Biochem Biophys Res Commun 378(3)
  
  Pages: 634-639
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Surface plasmon resonance characterization of specific binding of polyglutamine aggregation inhibitors to the expanded polyglutamine stretch2009
- Author(s)
  Okamoto Y, Nagai Y, Fujikake N, Popiel HA, Yoshioka T, Toda T, Inui T
- Journal Title
  
  Biochem. Biophys. Res. Commun. 378
  
  Pages: 634-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Journal Article] Delivery of the aggregate inhibitor peptide QBP1 into the mouse brain using PTDs and its therapeutic effects on polyglutamine disease mice2009
- Author(s)
  Popiel HA, Nagai Y, Fujikake N, Toda T
- Journal Title
  
  Neurosci. Lett. 449
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Journal Article] Conformational changes and aggregation of expanded polyglutamine proteins as therapeutic targets of the polyglutamine diseases : Exposed β-sheet hypothesis2008
- Author(s)
  永井義隆, ポピエル明子
- Journal Title
  
  Curr Pharm Des 14(30)
  
  Pages: 3267-3279
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Conformational changes and aggregation of expanded polyglutamine proteins as therapeutic targets of the polyglutamine diseases: exposed β-sheet hypothesis2008
- Author(s)
  Nagai Y, Popiel HA
- Journal Title
  
  Curr. Pharm. Des. 14
  
  Pages: 3267-3279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Journal Article] Heat shock transcription factor 1 (HSF1)-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones2008
- Author(s)
  Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T
- Journal Title
  
  J Biol Chem 283(38)
  
  Pages: 26188-26197
- Data Source
  KAKENHI-PROJECT-20390245
[Journal Article] Heat shock transcription factor-1 activating compounds suppress polyglutamine induced neurodegeneration through induction of multiple molecular chaperones2008
- Author(s)
  Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 26188-26197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] Identification of a polyglutamine oligomerization inhibitor with high brain permeability and safety, which exerts therapeutic effects on multiple mouse models of the polyglutamine diseases2013
- Author(s)
  H.A. Popiel, H. Yamane, T. Takahashi, M. Tada, Y. Saitoh, H. Fujita, Y. Okamoto, T. Toda, K. Wada, O. Onodera, Y. Nagai
- Organizer
  Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley, USA
- Data Source
  KAKENHI-PROJECT-24591287
[Presentation] Non-cell autonomous therapeutic effects of Hsp40 on polyglutamine disease models via its exosome-mediated secretion2012
- Author(s)
  Nagai Y, Takeuchi T, Popiel HA, Wada K
- Organizer
  2nd International Conference of Neural Cell Culture
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591287
[Presentation] 凝集阻害分子の遺伝子治療によるポリグルタミン病モデルマウスに対する治療効果2011
- Author(s)
  ポピエルヘレナ明子
- Organizer
  第52回に本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] 凝集阻害分子の遺伝子治療によるポリグルタミン病モデルマウスに対する治療効果2011
- Author(s)
  ポピエルヘレナ明子, 他
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Hsp40 exerts non-cell autonomous therapeutic effects on polyglutamine disease mice via its unconventional secretion2011
- Author(s)
  Popiel H.A., et al
- Organizer
  6^<th> Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  II Ciocco Tuscany Resort, Italy
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] 凝集阻害分子の遺伝子治療によるポリグルタミン病モデルマウスに対する治療効果2011
- Author(s)
  ポピエルヘレナ明子
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場,名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] 凝集阻害分子の遺伝子治療によるポリグルタミン病モデルマウスに対する治療効果2011
- Author(s)
  ポピエルヘレナ明子, 他
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] Hsp40 exerts non-cell autonomous therapeutic effects on polyglutamine disease mice via its unconventional secretion2011
- Author(s)
  Popiel H.A.
- Organizer
  6th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Garga, Italy
- Data Source
  KAKENHI-PUBLICLY-22020038
[Presentation] 凝集阻害分子の遺伝子治療によるポリグルタミン病モデルマウスに対する治療効果2011
- Author(s)
  ポピエル明子
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PUBLICLY-22020038
[Presentation] ポリグルタミン病モデルマウスに対する凝集阻害分子の遺伝子治療による効果2011
- Author(s)
  ポピエル明子
- Organizer
  平成23年度包括型脳科学研究推進支援ネットワーク夏のワークショップ
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PUBLICLY-22020038
[Presentation] Hsp40 exerts non-cell autonomous therapeutic effects on polygiutamine disease mice via its unconventional secretion2011
- Author(s)
  Popiel H.A., et al
- Organizer
  6^<th> Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  II Ciocco Tuscany Resort, Italy
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] Hsp40 exerts non-cell autonomous therapeutic effects on polyglutamine disease mice via its unconventional secretion2011
- Author(s)
  Popiel HA
- Organizer
  6^<th> Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Il Ciocco Tuscany Resort, Italy
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] 凝集阻害分子を用いた遺伝子治療によるポリグルタミン病モデルマウスの神経症状と封入体形成の抑制2010
- Author(s)
  ポピエル明子, 他
- Organizer
  第33回日本神経科学会・第53回日本神経化学会合同大会
- Place of Presentation
  神戸コンベンションセンター(兵庫)
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Molecular chaperone gene therapy ameliorates neurological phenotypes and protein aggregation in polyglutamine neurodegenerative disease mice2010
- Author(s)
  Popiel HA
- Organizer
  3^<rd> International Symposium on Protein Community
- Place of Presentation
  ホテル日航奈良,奈良
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] Molecular chaperone gene therapy ameliorates neurological phenotypes and protein aggregation in polyglutamine neurodegenerative disease mice.2010
- Author(s)
  Popiel H.A., et al.
- Organizer
  3rd International Symposium on Protein Community
- Place of Presentation
  ホテル日航奈良(奈良)
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Molecular chaperone gene therapy ameliorates neurological phenotypes and protein aggregation in polyglutamine neurodegenerative disease mice.2010
- Author(s)
  Popiel H.A., et al.
- Organizer
  3rd International Symposium on Protein Community
- Place of Presentation
  ホテル日航奈良(奈良)
- Data Source
  KAKENHI-PUBLICLY-22020038
[Presentation] 凝集阻害分子を用いた遺伝子治療によるポリグルタミン病モデルマウスの神経症状と封入体形成の抑制2010
- Author(s)
  ポピエル明子, 他
- Organizer
  第33回日本神経科学会・第53回日本神経化学会合同大会
- Place of Presentation
  神戸コンベンションセンター(兵庫)
- Data Source
  KAKENHI-PUBLICLY-22020038
[Presentation] Molecular chaperone gene therapy ameliorates neurological phenotypes and protein aggregation in polyglutamine neurodegenerative disease mice2010
- Author(s)
  Popiel HA
- Organizer
  3^<rd> International Symposium on Protein Community
- Place of Presentation
  奈良
- Year and Date
  2010-09-13
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] 凝集阻害分子を用いた遺伝子治療によるポリグルタミン病モデルマウスの神経症状と封入体形成の抑制2010
- Author(s)
  ポピエル明子, 他
- Organizer
  第33回日本神経科学会・第53回日本神経化学会合同大会
- Place of Presentation
  神戸コンベンションセンター(兵庫)
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] 凝集阻害分子を用いた遺伝子治療によるポリグルタミン病も出るマウスの神経症状と封入体形成の抑制2010
- Author(s)
  ポピエル明子
- Organizer
  第33回に本神経科学会・第53回日本神経化学会合同大会
- Place of Presentation
  神戸コンベンションセンター,兵庫
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] Molecular chaperone gene therapy ameliorates neurological phenotypes and protein aggregation in polyglutamine neurodegenerative disease mice.2010
- Author(s)
  Popiel H.A., et al.
- Organizer
  3rd International Symposium on Protein Community
- Place of Presentation
  ホテル日航奈良(奈良)
- Data Source
  KAKENHI-PROJECT-22790837
[Presentation] Molecular chaperone gene therapy ameliorates neurological phenotypes and protein aggregation in polyglutamine neurodegenerative disease mice.2010
- Author(s)
  Popiel H.A., et al.
- Organizer
  3rd International Symposium on Protein Community
- Place of Presentation
  ホテル日航奈良(奈良)
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] 凝集阻害分子を用いた遺伝子治療によるポリグルタミン病モデルマウスの神経症状と封入体形成の抑制2010
- Author(s)
  ポピエル明子, 他
- Organizer
  第33回日本神経科学会・第53回日本神経化学会合同大会
- Place of Presentation
  神戸コンベンションセンター(兵庫)
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] 凝集阻害分子を用いた遺伝子治療によるポリグルタミン病モデルマウスの神経症状と封入体形成の抑制2010
- Author(s)
  ポピエル明子
- Organizer
  第33回日本神経科学会・第53回日本神経科学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] 17-AAG, an HSF1-activator, suppresses polyglutamine-induced neurodegeneration via induction of molecular chaperones2009
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Sapporo Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] Opposing effects of HSF1 expression on tau-and polyglutamine-induced neurodegeneration in vivo2009
- Author(s)
  Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Sapporo Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] 凝集阻害ペプチドQBP1を用いたポリグルタミン病に対する分子標的治療法の開発2009
- Author(s)
  永井義隆, ポピエル明子, 藤掛伸宏, 村松慎一, 戸田達史, 和田圭司
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  グランドプリンスホテル高輪、東京
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Opposing effects of HSF1 expression on tau-and polyglutamine-inducedneurodegeneration in vivo.2009
- Author(s)
  Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th Intemational Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] 凝集阻害ペプチドQBP1を用いたポリグルタミン病に対する分子標的治療法の開発2009
- Author(s)
  永井義隆, ポピエル明子, 藤掛伸宏, 村松慎一, 戸田達史, 和田圭司
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  グランドプリンスホテル高輪、東京
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] Towards designing chemical analogues of the polyglutamine aggregation inhibitor peptide QBP1 : a structure-activity relationship study on QBP1.2009
- Author(s)
  Popiel HA, Tomita K, Oishi S, Fuju N, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conferenceon CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20059023
[Presentation] Towards designing chemical analogues of the polyglutamine aggregation inhibitor peptide QBP1: a structure-activity relationship study on QBP12009
- Author(s)
  Popiel HA
- Organizer
  5th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] Surtace plasmon resonance as a useful technique for screening for specific polyglutamine aggregation inhibitors.2009
- Author(s)
  Nagai Y, Okamoto Y, Fujikake N, Popiel HA, Inui T, Wada K
- Organizer
  5th Gordon Research Conferenceon CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] ポリグルタミン病モデルマウスに対する凝集阻害ペプチドQBP1を用いた遺伝子治療2009
- Author(s)
  ポピエル明子, 藤掛伸宏, 戸田達史, 村松慎一, 和田圭司, 永井義隆
- Organizer
  第82回日本生化学会
- Place of Presentation
  ポートアイランド、神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] Pharmacological activation of heat shock transcription factor 1 suppresses polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones.2009
- Author(s)
  Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] Towards designing chemical analogues of the potyglutamine aggregation inhibitor peptide QBP1 : a structure-activity relationship study on QBP12009
- Author(s)
  Popiel HA, Tomita K, Oishi S, Fujii N, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conferenceon CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] Surface ptasmon resonance as a useful technique for screening for specific polyglutamine aggregation inhibitors.2009
- Author(s)
  Nagai Y, Okamoto Y, Fujikake N, Popiel HA, Inui T, Wada K
- Organizer
  5th Gordon Research Conferenceon CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] 熱ショック転写因子(HSF1)活性剤は分子シャペロン群の発現を誘導し、ポリグルタミン病の神経変性を抑制する2009
- Author(s)
  永井義隆, 藤掛伸宏, ポピエル明子, 岡本佑馬, 山口政光, 戸田達史, 和田圭司
- Organizer
  第52回日本神経化学会
- Place of Presentation
  伊香保温泉ホテル天坊、群馬
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] 熱ショック転写因子(HSF1)活性剤は分子シャペロン群の発現を誘導し、ポリグルタミン病の神経変性を抑制する2009
- Author(s)
  永井義隆, 藤掛伸宏, ポピエル明子, 岡本佑馬, 山口政光, 戸田達史, 和田圭司
- Organizer
  第52回日本神経化学会
- Place of Presentation
  伊香保温泉ホテル天坊、群馬
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] 熱ショック転写因子(HSF1)活性剤は分子シャペロン群の発現を誘導し、ポリグルタミン病の神経変性を抑制する2009
- Author(s)
  永井義隆, 藤掛伸宏, ポピエル明子, 岡本佑馬, 山口政光, 戸田達史, 和田圭司
- Organizer
  第52回日本神経化学会
- Place of Presentation
  伊香保温泉ホテル天坊、群馬
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Towards designing chemical analogues of the polyglutamine aggregation inhibitor peptide QBP1 : a structure-activity_relationship study on QBP12009
- Author(s)
  Popiel HA, Tomita K, Oishi S, Fujii N, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Surface plasmon resonance as a useful technique for screening for specific polyglutamine aggregation inhibitors.2009
- Author(s)
  Nagai Y, Okamoto Y, Fujikake N, Popiel HA, Inui T, Wada K
- Organizer
  5th Gordon Research Conferenceon CAG'Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20059023
[Presentation] Opposing effects of HSF1 expression on tau- and polyglutamine-induced neurodegeneration in vivo.2009
- Author(s)
  Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th Intemational Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] Pharmacological activation of heat shock transcription factor 1 suppresses polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones2009
- Author(s)
  Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] ポリグルタミン病モデルマウスに対する凝集阻害ペプチドQBP1を用いた遺伝子治療2009
- Author(s)
  ポピエル明子
- Organizer
  第82回日本生化学会
- Place of Presentation
  ポートアイランド, 神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] ポリグルタミン病モデルマウスに対する凝集阻害ペプチドQBP1を用いた遺伝子治療2009
- Author(s)
  ポピエル明子, 藤掛伸宏, 戸田達史, 村松慎一, 和田圭司, 永井義隆
- Organizer
  第82回日本生化学会
- Place of Presentation
  ポートアイランド、神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20059023
[Presentation] 17-AAG, an HSF1-activator, suppresses polyglutamine-induced neurodegeneration via induction of molecular chaperones2009
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th Intemational Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] ポリグルタミン病モデルマウスに対する凝集阻害ペプチドQBP1 を用いた遺伝子治療2009
- Author(s)
  ポピエル明子
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Towards designing chemical analogues of the polyglutamine aggregation inhibitor peptide QBP1 : a structure-activity relationship study on QBP12009
- Author(s)
  Popiel HA, Tomita K, Oishi S, Fujii N, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] 凝集阻害ペプチドQBP1を用いたポリグルタミン病に対する分子標的治療法の開発2009
- Author(s)
  永井義隆, ポピエル明子, 藤掛伸宏, 村松慎一, 戸田達史, 和田圭司
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  グランドプリンスホテル高輪、東京
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20059023
[Presentation] 17-AAG, an HSF1-activator, suppresses polyglutamine-induced neurodegeneration via induction of molecular chaperones2009
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th Intemational Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] Opposing effects of HSF1 expression on tau- and polyglutamine-induced neurodegeneration in vivo.2009
- Author(s)
  Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Sapporo Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20059023
[Presentation] Phamacological activation of heat shock transcription facton 1 suppresses polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones.2009
- Author(s)
  Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] ポリグルタミン病モデルマウスに対する凝集阻害ペプチドQBP1を用いた遺伝子治療2009
- Author(s)
  ポピエル明子, 藤掛伸宏, 戸田達史, 村松慎一, 和田圭司, 永井義隆
- Organizer
  第82回日本生化学会
- Place of Presentation
  ポートアイランド、神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] 凝集阻害ペプチドQBP1を用いたポリグルタミン病に対する分子標的治療法の開発2009
- Author(s)
  永井義隆, ポピエル明子, 藤掛伸宏, 村松慎一, 戸田達史, 和田圭司
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  グランドプリンスホテル高輪、東京
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] Pharmacological activation of heat shock transcription factor 1 suppresses polyglutamine-induced neurodegeneration through induction of multiplemolecular chaperones.2009
- Author(s)
  Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K, Nagai Y
- Organizer
  5th Gordon Research Conferenceon CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20059023
[Presentation] ポリグルタミン病モデルマウスに対する凝集阻害ペプチドQBP1を用いた遺伝子治療2009
- Author(s)
  ポピエルレ明子, 藤掛伸宏, 戸田達史, 村松慎一, 和田圭司, 永井義隆
- Organizer
  第82回日本生化学会
- Place of Presentation
  ポートアイランド、神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20700336
[Presentation] 17-AAG, an HSFI-activator, suppresses polyglutamine-inducedneurodegeneration via induction of molecular chaperones.2009
- Author(s)
  Nagai Y, Fujikake N, Popiel HA, Okamoto Y, Yamaguchi M, Toda T, Wada K
- Organizer
  4th International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Gateaux Kingdom Sapporo Hotel & Spa Resort, Sapporo, Japan
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20059023
[Presentation] Towards designing chemical analogues of the polyglutamine aggregation inhibitor peptide QBP1: a structure-activity relationship study on QBP12009
- Author(s)
  Popiel HA
- Organizer
  5^<th> Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  New Hampshire, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-21200072
[Presentation] Surface plasmon resonance as a useful technique for screening for specific polyglutamine aggregation inhibitors2009
- Author(s)
  Nagai Y, Okamoto Y, Fujikake N, Popiel HA, Inui T, Wada K
- Organizer
  5th Gordon Research Conference on CAG Triplet Repeat Disorders
- Place of Presentation
  Waterville Valley Resort, USA
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20390245
[Presentation] 熱ショック転写因子(HSF1)活性剤は分子シャペロン群の発現を誘導し、ポリグルタミン病の神経変性を抑制する2009
- Author(s)
  永井義隆, 藤掛伸宏, ポピエル明子, 岡本佑馬, 山口政光, 戸田達史, 和田圭司
- Organizer
  第52回日本神経化学会
- Place of Presentation
  伊香保温泉ホテル天坊、群馬
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-20059023

1. NAGAI Yoshitaka (60335354)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
2. AOKI Masashi (70302148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 藤掛伸宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Popiel Helena Akiko ポピエル ヘレナ・明子

POPIEL HELENA Akiko ポピエル ヘレナ 明子

ポピエル ヘレナ・アキコ ポピエル ヘレナ・アキコ

POPIEL Helena Akiko ポピエル ヘレナ明子

POPIE HELENA Akiko ポピエル ヘレナ 明子

Research Projects

Research Products

Co-Researchers

Establishment of a molecular therapy for the polyglutamine diseases targeting toxic oligomersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アミロイド性タンパク質凝集体の細胞間・個体間の伝播・感染メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapy for the polyglutamine diseases via selection of oligomer inhibitors using new technologies SPR & FCSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Demonstration of the abnormal conformational transition of amyloid proteins and it's application as an early diagnostic toolPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ミスフォールディング病に対する内在性分子シャペロン発現誘導による治療法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular therapy for the polyglutamine diseases targeting the toxic β-sheet conformers and oligomers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular therapy for the polyglutamine diseases using a novel brain delivery method of aggregate inhibitor peptidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] p62 plays a protective role in the autophagic degradation of polyglutamine protein oligomers in polyglutamine disease model flies.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peptide-Based Therapeutic Approaches for Treatment of the Polyglutamine Diseases2014

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of protein misfolding/aggregation using polyglutamine binding peptide QBP1 as a therapy for the polyglutamine diseases2013

Author(s)

Journal Title

URL

Data Source

[Journal Article] Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hsp40 Gene Therapy Exerts Therapeutic Effects on Polyglutamine Disease Micevia a Non-Cell Autonomous Mechanism.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The aggregation inhibitor peptide QBP1 as a therapeutic molecule for the polyglutamine neurodegenerative diseases2011

Popiel Helena Akiko ポピエルヘレナ・明子

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