XU YAN 徐岩

… Alternative Names

XU Yan 徐岩

Less

Researcher Number	40506763
Other IDs
Affiliation (Current)	2025: 宮崎大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 宮崎大学, 医学部, 教授 2010 – 2015: 宮崎大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Bio-related chemistry / Chemical biology / Chemistry related to living body Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 52040:Radiological sciences-related / Bio-related chemistry / Chemistry / Science and Engineering
Keywords	Principal Investigator 核酸 / 生体分子 / 分子プローブ / 四重鎖構造 / DNA・RNA高次構造 / 19F-NMR / 創薬 / テロメアRNA / 癌治療法 / クリック反応 … More / RNA高次構造 / 有機化学 / ケミカルバイオロジー / テロメアRNA高次構造 / 糖 / バイオテクノロジー / 可視化 / ヒトテロメアRNA / ヒトテロメアDNA / テロメア / 抗がん分子 / 化学的アプローチ / ヒトテロメア RNA / テロメア DNA … More Except Principal Investigator light emitted diode / 腫瘍集積性 / 光線力学的療法 / 胆管癌 / 造影剤 / クリック反応 / ゲノム / クリック反応技術 / 糖鎖連結ポルフィリン錯体 / 分子結合 / バイオマーカー / 癌 / MRI / レーザ治療 / 細胞増殖阻止 / ポルフィリン誘導体 / 細胞内局在と細胞死機序 / 水溶性光増感剤 / 糖鎖連結型 / 水溶性ポルフィリン / LED / 消化器癌治療 / 光線力学学的療法 / CT / 分子イメージング / DNA損傷 / テロメア / DNAメチル化 / DNA結合タンパク質 / エピゲノム / ゲノム断片分離 / インベージョン / PNA / バイテクノロジー / 相同組換え / 人工酵素 / ペプチド / 相同組替え / ゲノム編集 / 遺伝子操作 / 核酸 / バイオテクノロジー / 遺伝子 / セリウム / 遺伝子組換え / ペプチド核酸 / 制限酵素 / DNA Less

Chemical Biology Aimed at Elucidating the Structure, Function, and Interaction with Proteins of Non-canonical Nucleic AcidsPrincipal Investigator
- Principal Investigator
  
  徐岩
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  University of Miyazaki
クリック反応技術と軸配位子糖鎖連結ポルフィリン錯体を融合した革新的PDTの開発
- Principal Investigator
  
  七島篤志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Miyazaki
19F NMR分子技術の開発によるヒト細胞内DNA及びRNA高次構造の解明Principal Investigator
- Principal Investigator
  
  徐岩
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  University of Miyazaki
Development of Innovative Cancer MRI Imaging Techniques Using New Contrast Agents Based on Molecular Binding Technology
- Principal Investigator
  
  Hirai Toshinori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kumamoto University
分子結合技術を用いた造影剤による革新的がんCT画像化技術の開発
- Principal Investigator
  
  水谷陽一
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Miyazaki
Development of the enhanced effect and less invasiveness of new photodynamic therapy for bilie duct carcinoma
- Principal Investigator
  
  NANASHIMA ATSUSHI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Miyazaki
Structure and reactivity of human telomere RNA and development of new cancer therapy for targeting telomerePrincipal Investigator
- Principal Investigator
  
  XU Yan
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  University of Miyazaki
Creation of new genome science using chemical tools to precisely detect modification and damage of human genome
- Principal Investigator
  
  Komiyama Makoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bio-related chemistry
- Research Institution
  National Institute for Materials Science
Chemical biology for elucidation of molecular basis of telomeric RNA G-quadruplex structurePrincipal Investigator
- Principal Investigator
  
  XU YAN
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  University of Miyazaki
Development of visualization technique of cancer cell by click chemistryPrincipal Investigator
- Principal Investigator
  
  XU YAN
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  University of Miyazaki
Structure elucidation of human telomeric DNA and RNA in cells by chemical approach and its applicationPrincipal Investigator
- Principal Investigator
  
  XU Yan
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  University of Miyazaki
Creation of genome manipulation technology using super restriction enzyme
- Principal Investigator
  
  KOMIYAMA Makoto
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  University of Tsukuba
  The University of Tokyo

[Book] Oligonucleotide Containing 8-Trifluoromethyl-2′-Deoxyguanosine as a Z-DNA Probe. In: Kim, K.K., Subramani, V.K. (eds) Z-DNA.2023
- Author(s)
  Hong-Liang Bao and Yan Xu
- Total Pages
  332
- Publisher
  Humana, New York, NY
- ISBN
  9781071630839
- Data Source
  KAKENHI-PROJECT-21H02081
[Book] In Cell 19F NMR for G-quadruplex. In: Sugimoto, N. (eds) Handbook of Chemical Biology of Nucleic Acids.2023
- Author(s)
  Yan Xu
- Total Pages
  2650
- Publisher
  Springer, Singapore
- ISBN
  9789811613135
- Data Source
  KAKENHI-PROJECT-21H02081
[Book] Clipping of Telomere from Human Chromosomes using Chemistry-based Artificial Restriction DNA Cutter2015
- Author(s)
  T. Ishizuka, Y. Xu, M. Komiyama
- Total Pages
  13
- Publisher
  John Wiley & Sons, Inc.
- Data Source
  KAKENHI-PROJECT-26288083
[Book] DNA Conjugates and Sensors2012
- Author(s)
  M. Komiyama, Y. Xu and J. Sumaoka
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-24651264
[Journal Article] A fish herpesvirus highlights functional diversities among Zα domains related to phase separation induction and A-to-Z conversion2023
- Author(s)
  Diallo Mamadou Amadou、Pirotte Sebastien、Hu Yunlong、Morvan Lea、Rakus Krzysztof、Suarez Nicolas M、PoTsang Lee、Saneyoshi Hisao、Xu Yan、Davison Andrew J、Tompa Peter、Sussman Joel L、Vanderplasschen Alain
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 2 Pages: 806-830
- DOI
  10.1093/nar/gkac761
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05319, KAKENHI-PROJECT-21H02081
[Journal Article] An Advanced Detection System for <i>In Situ</i> Hybridization Using a Fluorescence Resonance Energy Transfer-based Molecular Beacon Probe2022
- Author(s)
  Narantsog Choijookhuu, Yasuaki Shibata, Takumi Ishizuka, Yan Xu, Takehiko Koji, Yoshitaka Hishikawa
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 55 Issue: 5 Pages: 119-128
- DOI
  10.1267/ahc.22-00075
- ISSN
  0044-5991, 1347-5800
- Year and Date
  2022-10-28
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05314, KAKENHI-PROJECT-21K06738, KAKENHI-PROJECT-21H02081, KAKENHI-PROJECT-20K07246
[Journal Article] Click chemistry for fluorescence imaging via combination of a BODIPY-based ‘turn-on’ probe and a norbornene glucosamine2022
- Author(s)
  Zhiyong He, Takumi Ishizuka, Yoshitaka Hishikawa, Yan Xu
- Journal Title
  
  Chemical Communications
  
  Volume: 58 Issue: 89 Pages: 12479-12482
- DOI
  10.1039/d2cc05359d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05314, KAKENHI-PROJECT-21K06738, KAKENHI-PROJECT-22K08806
[Journal Article] ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis2022
- Author(s)
  Zhang Ting、Yin Chaoran、Fedorov Aleksandr、Qiao Liangjun、Bao Hongliang、Beknazarov Nazar、Wang Shiyu、Gautam Avishekh、Williams Riley M.、Crawford Jeremy Chase、Peri Suraj、Studitsky Vasily、Beg Amer A.、Thomas Paul G.、Walkley Carl、Xu Yan、Poptsova Maria、Herbert Alan、Balachandran Siddharth
- Journal Title
  
  Nature
  
  Volume: 606 Issue: 7914 Pages: 594-602
- DOI
  10.1038/s41586-022-04753-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Journal Article] ADAR1 masks the cancer immunotherapeutic potential of ZBP1-driven necroptosis2022
- Author(s)
  Ting Zhang, Chaoran Yin, Aleksandr Fedorov, Liangjun Qiao, Hongliang Bao, Nazar Beknazarov, Shiyu Wang, Avishekh Gautam, Suraj Peri, Vasily Studitsky, Carl Walkley, Yan Xu, Maria Poptsova, Alan Herbert, Riley Williams, Jeremy Crawford, Amer Beg, Paul Thomas, Siddharth Balachandran
- Journal Title
  
  Nature
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Journal Article] Systematic Approach to DNA Aptamer Design Using Amino Acid?Nucleic Acid Hybrids (ANHs) Targeting Thrombin2021
- Author(s)
  Yum Ji Hye、Ishizuka Takumi、Fukumoto Koyuki、Hori Daisuke、Bao Hong-Liang、Xu Yan、Sugiyama Hiroshi、Park Soyoung
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: 7 Issue: 4 Pages: 1338-1343
- DOI
  10.1021/acsbiomaterials.1c00060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15402, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-18K05315, KAKENHI-PROJECT-21H02081
[Journal Article] A Small Ligand That Selectively Binds to the G-quadruplex at the Human Vascular Endothelial Growth Factor Internal Ribosomal Entry Site and Represses the Translation2021
- Author(s)
  Hu Xiao-Xia、Wang Sheng-Quan、Gan Shi-Quan、Liu Lei、Zhong Ming-Qing、Jia Meng-Hao、Jiang Fei、Xu Yan、Xiao Chao-Da、Shen Xiang-Chun
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 9
- DOI
  10.3389/fchem.2021.781198
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Journal Article] Observation of Z‐DNA Structure via the Synthesis of Oligonucleotide DNA Containing 8‐Trifluoromethyl‐2‐Deoxyguanosine2021
- Author(s)
  Bao Hong‐Liang、Xu Yan
- Journal Title
  
  Current Protocols
  
  Volume: 1 Issue: 1
- DOI
  10.1002/cpz1.28
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15402, KAKENHI-PROJECT-17H03091
[Journal Article] Characterization of Structure and Catalytic Activity of a Complex between Heme and an All Parallel-Stranded Tetrameric G-Quadruplex Formed from DNA/RNA Chimera Sequence d(TTA)r(GGG)dT2020
- Author(s)
  Hayasaka Kosuke、Shibata Tomokazu、Sugahara Aya、Momotake Atsuya、Matsui Toru、Neya Saburo、Ishizuka Takumi、Xu Yan、Yamamoto Yasuhiko
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 93 Issue: 5 Pages: 621-629
- DOI
  10.1246/bcsj.20200013
- NAID
  130007842975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0048, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-19H02824
[Journal Article] Oligonucleotides DNA containing 8-trifluoromethyl-2’-deoxyguanosine for observing Z-DNA structure.2020
- Author(s)
  Bao, H.-L., Masuzawa, T., Oyoshi, T., Xu, Y.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 48 Pages: 7041-7051
- DOI
  10.1093/nar/gkaa505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05704, KAKENHI-PROJECT-20K15402, KAKENHI-PROJECT-17H03091
[Journal Article] Improving Thermodynamic Stability and Anticoagulant Activity of a Thrombin Binding Aptamer by Incorporation of 8-trifluoromethyl-2′-deoxyguanosine2020
- Author(s)
  Bao Hong-Liang、Ishizuka Takumi、Yamashita Atsushi、Furukoji Eiji、Asada Yujiro、Xu Yan
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 1 Pages: 711-718
- DOI
  10.1021/acs.jmedchem.0c01711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15402, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-19H03445
[Journal Article] Telomeric DNA-RNA-hybrid G-quadruplex exists in environmental conditions of HeLa cells2020
- Author(s)
  Hong-Liang Bao and Yan Xu
- Journal Title
  
  Chemical Communications
  
  Volume: 56 Issue: 48 Pages: 6547-6550
- DOI
  10.1039/d0cc02053b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] Conformation of G-quadruplex Controlled by Click Reaction2020
- Author(s)
  Chao-Da Xiao, Zhi-Yong He, Chuan-Xin Guo, Xiang-Chun Shen and Yan Xu
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 18 Pages: 4339-4339
- DOI
  10.3390/molecules25184339
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] Linear consecutive hexaoxazoles as G4 ligands inducing chair-type anti-parallel topology of a telomeric G-quadruplex2020
- Author(s)
  Sasaki Shogo、Ma Yue、Ishizuka Takumi、Bao Hong-Liang、Hirokawa Takatsugu、Xu Yan、Tera Masayuki、Nagasawa Kazuo
- Journal Title
  
  RSC Advances
  
  Volume: 10 Issue: 71 Pages: 43319-43323
- DOI
  10.1039/d0ra09413g
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05743, KAKENHI-PROJECT-20K15402, KAKENHI-PUBLICLY-18H04387, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-20K15411, KAKENHI-PROJECT-20H02876, KAKENHI-PROJECT-20J13814
[Journal Article] Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis2020
- Author(s)
  Zhang, T., C. Yin, D., Boyd, F., Quarato, G., Shubina, M., Ragan, K. B., Ishizuka, T., Xu, Y., Balachandran, S. et al.
- Journal Title
  
  Cell
  
  Volume: 180 Issue: 6 Pages: 1115-1129
- DOI
  10.1016/j.cell.2020.02.050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] Stability and properties of Z-DNA containing artificial nucleobase 2′-O-methyl-8-methyl guanosine2019
- Author(s)
  T. Balasubramaniyam, T. Ishizuka, Y. Xu*
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 2 Pages: 364-369
- DOI
  10.1016/j.bmc.2018.12.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] 19F NMR spectroscopy for the analysis of DNA G-quadruplex structures using 19F-labeled nucleobase2019
- Author(s)
  T. Ishizuka, H. L. Bao, Y. Xu*
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2035 Pages: 407-433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] A Nucleoside Derivative 5-Vinyluridine (VrU) for Imaging RNA in Cells and Animals2019
- Author(s)
  Liu Hong-shan、Ishizuka Takumi、Kawaguchi Makiko、Nishii Ryuichi、Kataoka Hiroaki、Xu Yan
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 30 Issue: 11 Pages: 2958-2966
- DOI
  10.1021/acs.bioconjchem.9b00643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05175, KAKENHI-PROJECT-16H05397, KAKENHI-PROJECT-17H03091
[Journal Article] Hybrid-type and two-tetrad antiparallel telosmere DNA G-quadruplex structures in living human cells2019
- Author(s)
  H. L. Bao, H. S. Liu, Y. Xu*
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 10 Pages: 4940-4947
- DOI
  10.1093/nar/gkz276
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] 2′-O-Methyl-8-methylguanosine as a Z-Form RNA Stabilizer for Structural and Functional Study of Z-RNA2018
- Author(s)
  T. Balasubramaniyam, T. Ishizuka, C. D. Xiao, H. L. Bao, Y. Xu*
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 10 Pages: 2572-2572
- DOI
  10.3390/molecules23102572
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] HnRNPA1 Specifically Recognizes the Base of Nucleotide at the Loop of RNA G-Quadruplex2018
- Author(s)
  Xiao Liu and Yan Xu
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 1 Pages: 237-237
- DOI
  10.3390/molecules23010237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] An Intramolecular Antiparallel G-quadruplex Formed by Human Telomere RNA2018
- Author(s)
  Chao-Da Xiao, Tomokazu Shibata, Yasuhiko Yamamoto, and Yan Xu
- Journal Title
  
  Chemical Communications
  
  Volume: 54 Issue: 32 Pages: 3944-3946
- DOI
  10.1039/c8cc01427b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0048, KAKENHI-PROJECT-17H03091
[Journal Article] Recent progress in human telomere RNA structure and function2018
- Author(s)
  Yan Xu
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Issue: 15 Pages: 2577-2584
- DOI
  10.1016/j.bmcl.2018.06.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] Investigation of higher-order RNA G-quadruplex structures in vitro and in living cells by 19F NMR spectroscopy2018
- Author(s)
  Hong-Liang Bao and Yan Xu
- Journal Title
  
  Nature Protocols
  
  Volume: 13 Issue: 4 Pages: 652-665
- DOI
  10.1038/nprot.2017.156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03091
[Journal Article] A Simple and Sensitive 19F NMR Approach for Studying the Interaction of RNA G-Quadruplex with Ligand Molecule and Protein2017
- Author(s)
  H. L. Bao, T. Ishizuka, A. Iwanami, T. Oyoshi, Y. Xu*
- Journal Title
  
  ChemistrySelect
  
  Volume: － Issue: 15 Pages: 4170-4175
- DOI
  10.1002/slct.201700711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26288083, KAKENHI-PROJECT-17K05930, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-16K17938
[Journal Article] Studying DNA G-Quadruplex Aptamer by 19F NMR2017
- Author(s)
  Takumi Ishizuka, Atsushi Yamashita, Yujiro Asada, and Yan Xu
- Journal Title
  
  ACS Omega
  
  Volume: 2 Issue: 12 Pages: 8843-8848
- DOI
  10.1021/acsomega.7b01405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26288083, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-16K17938
[Journal Article] Allosteric control of nanomechanical DNA origami pinching devices for enhanced target binding2017
- Author(s)
  Akinori Kuzuya, Yusuke Sakai, Takahiro Yamazaki, Yan Xu, Yusei Yamanaka, Yuichi Ohya and Makoto Komiyama
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 59 Pages: 8276-8279
- DOI
  10.1039/c7cc03991c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26288083, KAKENHI-PROJECT-15H02189, KAKENHI-PROJECT-17H03091
[Journal Article] Unusual Topological RNA Architecture with an Eight-Stranded Helical Fragment Containing A-, G-, and U-Tetrads2017
- Author(s)
  C. D. Xiao, T. Ishizuka, X. Q. Zhu, Y. Li, H. Sugiyama, Y. Xu*
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 139 Issue: 7 Pages: 2565-2568
- DOI
  10.1021/jacs.6b12274
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26288083, KAKENHI-PROJECT-16K17938, KAKENHI-PROJECT-17H03091
[Journal Article] Structure-Dependent Binding of hnRNPA1 to Telomere RNA2017
- Author(s)
  Liu Xiao、Ishizuka Takumi、Bao Hong-Liang、Wada Kei、Takeda Yuma、Iida Keisuke、Nagasawa Kazuo、Yang Danzhou、Xu Yan
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 139 Issue: 22 Pages: 7533-7539
- DOI
  10.1021/jacs.7b01599
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13094, KAKENHI-PROJECT-26282214, KAKENHI-PROJECT-16H04754, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-16K17938, KAKENHI-PROJECT-16K18908
[Journal Article] Antiparallel RNA G-quadruplex Formed by Human Telomere RNA Containing 8-Bromoguanosine2017
- Author(s)
  Chao-Da Xiao, Takumi Ishizuka & Yan Xu
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 6695-6695
- DOI
  10.1038/s41598-017-07050-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-16K17938
[Journal Article] A multi-functional guanine derivative for studying the DNA G-quadruplex structure2017
- Author(s)
  Takumi Ishizuka, Pei-Yan Zhao, Hong-Liang Bao and Yan Xu
- Journal Title
  
  Analyst
  
  Volume: 142 Issue: 21 Pages: 4083-4088
- DOI
  10.1039/c7an00941k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26288083, KAKENHI-PROJECT-17H03091, KAKENHI-PROJECT-16K17938
[Journal Article] Characterization of Human Telomere RNA G-Quadruplex Structures in vitro and in Living Cells using 19F NMR Spectroscopy2017
- Author(s)
  H. L. Bao, T. Ishizuka, T. Sakamoto, K. Fujimoto, T. Uechi, N. Kenmochi, Y. Xu*
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: － Issue: 9 Pages: 5501-5511
- DOI
  10.1093/nar/gkx109
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26288083, KAKENHI-PROJECT-15K09656, KAKENHI-PROJECT-16K17938, KAKENHI-PROJECT-15K15367
[Journal Article] Click Chemistry Takes a Snapshot of DNA-RNA Hybrid G-Quadruplex in Living Cells2016
- Author(s)
  T. Ishizuka, Y. Xu*
- Journal Title
  
  J. Nat. Sci.
  
  Volume: 2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26288083
[Journal Article] Fluorescence Imaging of Chromosomal DNA using Click Chemistry2016
- Author(s)
  T. Ishizuka, H. S. Liu, K. Ito, Y. Xu*
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 33217-33217
- DOI
  10.1038/srep33217
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26288083, KAKENHI-PROJECT-16K17938
[Journal Article] Human Telomere RNA Structure and Function2016
- Author(s)
  Y. Xu*
- Journal Title
  
  Telomere and Telomerase
  
  Volume: 3
- DOI
  10.14800/tt.1455
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26288083
[Journal Article] Formation and stabilization of the telomeric antiparallel G-quadruplex and inhibition of telomerase by novel benzothioxanthene derivatives with anti-tumor activity2015
- Author(s)
  W. Zhang, M. Chen, Y. Ling Wu, Y. Tanaka, Y. Juan Ji, S. Lin Zhang, C. He Wei, Y. Xu
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 13693-13693
- DOI
  10.1038/srep13693
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288083
[Journal Article] Clipping of Telomere from Human Chromosomes using Chemistry-based Artificial Restriction DNA Cutter2015
- Author(s)
  T. Ishizuka, Y. Xu, and M. Komiyama
- Journal Title
  
  Curr. Protoc. Nucleic Acid Chem
  
  Volume: 61
- Description
  in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Clipping of Telomere from Human Chromosomes using Chemistry-based Artificial Restriction DNA Cutter2015
- Author(s)
  Takumi Ishizuka, Yan Xu, Makoto Komiyama
- Journal Title
  
  Curr. Protoc. Nucleic Acid Chem.
  
  Volume: in press Issue: 1
- DOI
  10.1002/0471142700.nc0613s61
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25888019, KAKENHI-PROJECT-22000007
[Journal Article] Finding of a human telomere DNA-RNA hybrid G-quadruplex formed by human telomeric 6-mer RNA and 16-mer DNA using click chemistry : Aprotective structure for telomere end2014
- Author(s)
  Y. Xu, Y. Suzuki, T. Ishizuka, C.-D. Xiao, X. Liu, T. Hayashi, and M. Komiyama
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 16 Pages: 4419-4421
- DOI
  10.1016/j.bmc.2014.05.053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-25888019, KAKENHI-PROJECT-26288083
[Journal Article] A Chemistry-Based Method to Detect Individual Telomere Lengths at a Single Chromosome Terminus2013
- Author(s)
  T. Ishizuka, Y. Xu, and M. Komiyama
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 1 Pages: 14-17
- DOI
  10.1021/ja308481c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-22350071, KAKENHI-PROJECT-24651264
[Journal Article] Direct light-up of cAMP derivatives in living cells by click reactions2013
- Author(s)
  K. Ito, H. Liu, M. Komiyama, T. Hayashi, and Y. Xu
- Journal Title
  
  Molecules
  
  Volume: 18 Issue: 10 Pages: 12909-12915
- DOI
  10.3390/molecules181012909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-24651264
[Journal Article] Conjugation of peptide nucleic acid with pyrrole-imidazole polyamide to specifically recognize and cleave DNA2013
- Author(s)
  W. Kameshima, T. Ishizuka, M. Minoshima, H. Sugiyama, Y. Xu, and M. Komiyama
- Journal Title
  
  Angew. Chem. Int. Ed. Engl.
  
  Volume: 52 Issue: 51 Pages: 13681-13684
- DOI
  10.1002/anie.201305489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-24651264
[Journal Article] Targeting Human Telomeric Higher-Order DNA : Dimeric G-quadruplex Units Serve as Preferred Binding Site2013
- Author(s)
  C. Zhao, L. Wu, J. Ren, Y. Xu and X. Qu
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 50 Pages: 18786-18789
- DOI
  10.1021/ja410723r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-24651264
[Journal Article] Evidence for G-quadruplex DNA in human cells2013
- Author(s)
  Y. Xu and M. Komiyama
- Journal Title
  
  Chembiochem.
  
  Volume: 14 Issue: 8 Pages: 927-928
- DOI
  10.1002/cbic.201300157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-22350071, KAKENHI-PROJECT-24651264
[Journal Article] SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome2012
- Author(s)
  N. Mulholland、YAN XU、H. Sugiyama 、K. Zhao
- Journal Title
  
  Cell & Bioscience
  
  Volume: Vol.2 Issue: 1
- DOI
  10.1186/2045-3701-2-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] Nanomechanical DNA origami 'single-molecule beacons' directly imaged by atomic force microscopy2012
- Author(s)
  Akinori Kuzuya
- Journal Title
  
  Nature Communications
  
  Volume: 1 Issue: 1 Pages: 449-449
- DOI
  10.1038/ncomms1452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220001, KAKENHI-PROJECT-22350071, KAKENHI-PROJECT-22750144, KAKENHI-PROJECT-23651129
[Journal Article] Oligonucleotide Models of Telomeric DNA and RNA Form a Hybrid G-quadruplex Structure as a Potential Component of Telomeres2012
- Author(s)
  Yan Xu, Takumi Ishizuka, Jie Yang, Kenichiro Ito, Hitoshi Katada, Makoto Komiyama, Tetsuya Hayashi
- Journal Title
  
  J. Bio. Chem.
  
  Volume: Vol. 287 Issue: 50 Pages: 41787-41796
- DOI
  10.1074/jbc.m112.342030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07372, KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-22350071, KAKENHI-PROJECT-24651264
[Journal Article] Human Telomere RNA: A Potential Target for Ligand Recognition2012
- Author(s)
  YAN XU
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: Vol.18 Issue: 14 Pages: 2096-2101
- DOI
  10.2174/138161212799958378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] G-rich Sequence-specific Recognition and Scission of Human Genome by PNA/DNA Hybrid G-quadruplex Formation2012
- Author(s)
  Takumi Ishizuka, Makoto Komiyama, Yan Xu
- Journal Title
  
  Angew. Chem., Int. Ed.
  
  Volume: Vol. 51 Issue: 29 Pages: 7198-7202
- DOI
  10.1002/anie.201201176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07372, KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-22350071, KAKENHI-PROJECT-24651264
[Journal Article] Structure, function and targeting of human telomere RNA2012
- Author(s)
  Y. Xu and M. Komiyama
- Journal Title
  
  Methods
  
  Volume: 57 Issue: 1 Pages: 100-105
- DOI
  10.1016/j.ymeth.2012.02.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-22350071, KAKENHI-PROJECT-24651264
[Journal Article] Human telomere RNA : a potential target for ligand recognition2012
- Author(s)
  徐岩(YAN XU)
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: Vol18 Pages: 2096-2101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] Inhibition of translation by small RNA-stabilized mRNA structures in human cells2011
- Author(s)
  K. Ito、S. Go、M. Komiyama、YAN XU
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: Vol.133 Issue: 47 Pages: 19153-19159
- DOI
  10.1021/ja206353c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA2011
- Author(s)
  YAN XU
- Journal Title
  
  Chemical Society Reviews
  
  Volume: Vol.40 Issue: 5 Pages: 2719-2740
- DOI
  10.1039/c0cs00134a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] Telomeric Repeat-Containing RNA Structure in Living Cells2010
- Author(s)
  徐岩(YAN XU)
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: Vol, 107 Pages: 14579-14584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] A 6-mer Photocontrolled Oligonucleotide as an Effective Telomerase Inhibitor2010
- Author(s)
  YAN XU、 K. Ito、 Y. Suzuki、 M. Komiyama
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: Vol.132 Issue: 2 Pages: 631-637
- DOI
  10.1021/ja907417r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] A U-Tetrad Stabilizes Human Telomeric RNA G-Quadruplex Structure2010
- Author(s)
  YAN XU 、T. Ishizuka 、T. Kimura 、M. Komiyama
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: Vol.132 Issue: 21 Pages: 7231-7233
- DOI
  10.1021/ja909708a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] A Chiral Wedge Molecule Inhibits Telomerase Activity2010
- Author(s)
  徐岩(YAN XU)
- Journal Title
  
  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  
  Volume: Vol, 132 Pages: 3778-3782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] A U-tetrad stabilizes human telomeric RNA G-quadruplex structure2010
- Author(s)
  Y.Xu
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 132 Pages: 7231-7233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] A U-Tetrad Stabilizes Human Telomeric RNA G-Quadruplex Structure2010
- Author(s)
  徐岩(YAN XU)
- Journal Title
  
  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  
  Volume: Vol, 132 Pages: 7231-7233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] A 6-mer Photocontrolled Oligonucleotide as an Effective Telomerase Inhibitor2010
- Author(s)
  徐岩(YAN XU)
- Journal Title
  
  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  
  Volume: Vol.132 Pages: 631-637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] Telomeric repeat-containing RNA structure in living cells2010
- Author(s)
  Y.Xu
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 4579-14584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Telomeric Repeat-Containing RNA Structure in Living Cells2010
- Author(s)
  YAN XU、 Y. Suzuki、 K. Ito、 M. Komiyama
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: Vol.107 Issue: 33 Pages: 14579-14584
- DOI
  10.1073/pnas.1001177107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Journal Article] A Chiral Wedge Molecule Inhibits Telomerase Activity2010
- Author(s)
  K. Shinohara、Y. Sannohe、S. Kaieda、K.Tanaka、 H. Osuga、 H.Tahara、 YAN XU、T. Kawase、T. Bando、H. Sugiyama
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: Vol.132 Issue: 11 Pages: 3778-3782
- DOI
  10.1021/ja908897j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350071
[Patent] 細胞標識剤及び細胞標識キット2019
- Inventor(s)
  徐岩、石塚匠、趙珮妍、肖潮達
- Industrial Property Rights Holder
  徐岩、石塚匠、趙珮妍、肖潮達
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17H03091
[Patent] グアノシン誘導体及びその製造法2019
- Inventor(s)
  徐岩、石塚匠、趙珮妍、肖潮達、西井龍一
- Industrial Property Rights Holder
  徐岩、石塚匠、趙珮妍、肖潮達、西井龍一
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17H03091
[Patent] 8位にフッ素原子含有官能基を有するグアノシン誘導体の製造法及びその応用2018
- Inventor(s)
  徐岩、石塚匠、鮑宏亮
- Industrial Property Rights Holder
  徐岩、石塚匠、鮑宏亮
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-172013
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H03091
[Patent] グアノシン誘導体及びその製造法2018
- Inventor(s)
  徐岩、石塚匠、趙珮妍、肖潮達
- Industrial Property Rights Holder
  徐岩、石塚匠、趙珮妍、肖潮達
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-093159
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Liquid to solid phase transition of short RNA promoted by RNA structure in neurodegenerative diseases.2022
- Author(s)
  Wang, S. Y., Xu, Y.
- Organizer
  第49回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] Combination of a near-infrared BODIPY derivative-based turn-on probe and a new norbornene-modified glucosamine derivative for in-cell and in vivo fluorescence imaging.2022
- Author(s)
  He, Z. Y., Xu, Y.
- Organizer
  第49回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] Unusual topological RNA G-quadruplex formed by an RNA duplex: Implications for the dimerization of COVID-19 RNA.2022
- Author(s)
  Song, Y., Wang, S. Y., Xu, Y.
- Organizer
  第49回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] Phase Transitions in the Assembly of Trifluoromethylated G-quadruplex RNA by shorter CGG Trinucleotide Repeats2021
- Author(s)
  Shiyu Wang, Yan Xu
- Organizer
  第48回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] A novel architecture of RNA G-quadruplex formed by SARS Cov-2 RNA2021
- Author(s)
  Yi Song, Shi-Yu Wang, Hong-Liang Bao, Yan Xu
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] Fluorescence imaging cell using inverse electron demand Diel-Alder reaction2021
- Author(s)
  Zhiyong He, Yan Xu
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] RNA二重鎖から形成される新規RNA G-quadruplex：COVID-19 mRNAの二量体化への影響2021
- Author(s)
  徐岩、宋藝、王詩宇
- Organizer
  第15回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] 8-Trifluoromethylated RNA composed of CGG trinucleotide repeats: synthesis, structure and phase transitions2021
- Author(s)
  Shiyu Wang, Hongliang Bao, Yan Xu
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] Dimerization of COVID-19 mRNA formed by an unusual topological RNA G-quadruplex2021
- Author(s)
  Yi Song, Shiyu Wang, Yan Xu
- Organizer
  第48回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02081
[Presentation] Ce(IV)/EDTA錯体によるRNA四重鎖構造の解析2020
- Author(s)
  石塚匠, 徐岩
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] 8.A trifluoromethylation 2’-deoxy-guanosine derivative for G-quadruplex and Z-DNA structure study2020
- Author(s)
  BAO, Hongliang; ISHIZUKA, Takumi; XU, Yan
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Improving stability and anticoagulant activity of thrombin binding aptamer by incorporation of 8-trifluoromethyl-2'-deoxyguanosine2019
- Author(s)
  Hongliang Bao, Takumi Ishizuka, Yan Xu
- Organizer
  日本化学会第99春季年会(2019)
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] 生体直交型反応による細胞及び生体内の蛍光イメージング2019
- Author(s)
  石塚匠, 劉泓汕, 徐岩
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Studying Telomeric DNA and RNA G-quadruplex Structures in vitro and in Living Human Cells by 19F NMR Spectroscopy2019
- Author(s)
  Bao H. L., Ishizuka T., Xu Y.
- Organizer
  The 7th International Meeting on Quadruplex Nucleic Acids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] In-cell 19F NMR: Telomere DNA G-quadruplex structures in living human cells2019
- Author(s)
  Hong-Liang Bao, Takumi Ishizuka, Yan Xu
- Organizer
  CISNAC2019日本核酸化学会設立記念国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Increase the anticoagulant activity of thrombin binding aptamer（TBA）by incorporation of 8-trifluoromethyl-2'-deoxyguanosine2019
- Author(s)
  鮑宏亮, 徐岩
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Fluorescence imaging in cell and in vivo by bioorthogonal reaction2019
- Author(s)
  Takumi Ishizuka, Hong-Shan Liu, Makiko Kawaguchi, Ryuichi Nishii, Hiroaki Kataoka, Yan Xu
- Organizer
  第46回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] A trifluoromethylation nucleoside derivative for Z-DNA structure study and nucleic acids therapeutics2019
- Author(s)
  Hong-Liang Bao, Takumi Ishizuka, Yan Xu
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] 8位修飾グアノシン誘導体によるin vivo RNAイメージング2019
- Author(s)
  石塚匠, 徐岩
- Organizer
  日本化学会第99春季年会(2019)
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] RNA四重鎖構造を解析する化学プローブの開発2018
- Author(s)
  大立目真臣、石塚匠、徐岩
- Organizer
  日本化学会第98春季年会(2018)
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Chemical probing of G-quadruplex structures by modified nuleosides2018
- Author(s)
  ISHIZUKA, Takumi; XU, Yan
- Organizer
  日本化学会第98春季年会(2018)
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] RNA四重鎖構造を解析する化学プローブの開発2018
- Author(s)
  大立目真臣、石塚匠、徐岩
- Organizer
  日本化学会第98春季年会(2018)
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Chemical probing of G-quadruplex structures by modified nuleosides2018
- Author(s)
  ISHIZUKA, Takumi; XU, Yan
- Organizer
  日本化学会第98春季年会(2018)
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] 8位修飾核酸グアノシン誘導体によるRNAイメージング2018
- Author(s)
  石塚匠, 肖潮達, 趙珮妍, 西井龍一, 徐岩
- Organizer
  第12回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] ケミカルツールを利用したヒトテロメアRNA 構造及び機能の解明2018
- Author(s)
  徐岩, 石塚匠, 肖潮達, 劉暁, 鮑宏亮
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] 蛍光分子イメージングにより実現する革新的がん可視化画像診断技術の開発2018
- Author(s)
  徐岩, 石塚匠, 趙珮妍
- Organizer
  第27回日本癌病態治療研究会
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] hnRNPA1のヒトテロメアRNAへの構造特異的な結合2018
- Author(s)
  竹田悠馬、劉暁、石塚匠、徐岩
- Organizer
  日本化学会第98春季年会(2018)
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Investigation of the thermodynamic stability and structure of oligonucleotides containing 2’-O-methyl-8-methyl guanosine by CD and NMR2018
- Author(s)
  BALASUBRAMANIYAM, Thananjeyan; ISHIZUKA, Takumi; XU, Yan
- Organizer
  日本化学会第98春季年会(2018)
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] 8-position modified 2’-deoxyguanosine derivatives for studying non-B DNA structures2018
- Author(s)
  Hongliang Bao, Takumi Ishizuka, Yan Xu
- Organizer
  第45回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Studying G-quadruplex structures by 19F NMR2018
- Author(s)
  BAO, Hongliang; ISHIZUKA, Takumi; XU, Yan
- Organizer
  日本化学会第98春季年会(2018)
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] 逆平行型ヒトテロメアRNA 四重鎖高次構造の発見2018
- Author(s)
  徐岩, 石塚匠, 肖潮達, 劉暁, 鮑宏亮, 柴田友和, 山本泰彦
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Chemical Probe for Studying Human Telomere RNA G-quadruplex2017
- Author(s)
  Takumi Ishizuka, Masaomi Otatsume, Yan Xu
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] ヒトテロメアRNAの構造及び生化学機能2017
- Author(s)
  徐岩、石塚匠、肖潮達、劉暁、鮑宏亮
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] RNA四重鎖構造を解析するケミカルプローブの開発2017
- Author(s)
  石塚匠、大立目真臣、徐岩
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] To investigate human telomere DNA G-quadruplexes structures by 19F NMR2017
- Author(s)
  Hongliang Bao, Takumi Ishizuka, Yan Xu
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Development　of　New　Chemical　Modification　Method　for　Analysis　of　Unique　G-Quadruplex　Structures2017
- Author(s)
  Yan Xu，Takumi Ishizuka，Balasubramaniyam Thananjeyan
- Organizer
  日本化学会第97春季年会（2017）
- Place of Presentation
  慶應義塾大学
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] RNA四重鎖構造を解析するケミカルプローブの開発2017
- Author(s)
  石塚匠、大立目真臣、徐岩
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] ヒトテロメアRNAの構造及び生化学機能2017
- Author(s)
  徐岩、石塚匠、肖潮達、劉暁、鮑宏亮
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Novel RNA Architecture Formed by Eight RNA Strands Containing Fourteen G- A- and U-tetrads2017
- Author(s)
  Chao-Da Xiao, Takumi Ishizuka, Yan Xu
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03091
[Presentation] Conformationally　Restricted　Guanosine　Analogues　Induce　Topological　Change　in　Human　Telomeric　DNA　G-Quadruplexes2016
- Author(s)
  Yan Xu，Takumi Ishizuka，Bao Hongliang，Liu Xiao，Balasubramaniyam Thananjeyan，Xiao Chaoda
- Organizer
  The　43th　International　Symposium　on　Nucleic　Acid　Chemistry（国際学会）
- Place of Presentation
  熊本大学
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] 修飾グアノシン誘導体により形成する核酸高次構造2016
- Author(s)
  徐岩，石塚匠
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] 光架橋反応を用いたヒトテロメアRNA四重鎖とhnRNPA1の相互作用解析2016
- Author(s)
  徐岩，石塚匠
- Organizer
  第38回日本光医学・光生物学会
- Place of Presentation
  京都リサーチパーク
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] ヒトテロメアRNA四重鎖とhnRNPA1の相互作用解析2016
- Author(s)
  石塚匠・劉暁・竹田悠馬・徐岩
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府京田辺市)
- Year and Date
  2016-03-25
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Specific binding of hnRNPA1 to human telomere RNA G-quadruplexes: a structure-dependent manner is required for telomere RNA and hnRNPA1 regulated telomere function2015
- Author(s)
  Xiao Liu, Takumi Ishizuka, Kei Wada, Yan Xu
- Organizer
  第42回国際核酸化学シンポジウム
- Place of Presentation
  あいめっせホール(兵庫県姫路市)
- Year and Date
  2015-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] 化学的アプローチを活用したケミカルバイオロジー2015
- Author(s)
  徐　岩・石塚　匠・肖　潮達・劉　暁・夏　岩・鮑　宏亮・劉　泓汕・Thananjeyan Balasubramaniyam
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学（熊本県熊本市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] 化学修飾核酸による四重鎖構造の解明2015
- Author(s)
  石塚　匠・徐　岩
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学（熊本県熊本市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] A Fluorine-labeled method for the investigation of G-quadruplex structure2015
- Author(s)
  Takumi Ishizuka, Yan Xu
- Organizer
  第42回国際核酸化学シンポジウム
- Place of Presentation
  あいめっせホール(兵庫県姫路市)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Characterization of human telomere RNA and RNA/DNA hybrid G-quadruplex structures in vitro and in living cells using 19F NMR spectroscopy2015
- Author(s)
  Hong-Liang Bao, Takumi Ishizuka, Yan Xu
- Organizer
  第42回国際核酸化学シンポジウム
- Place of Presentation
  あいめっせホール(兵庫県姫路市)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Elucidation of human telomeric RNA G-quadruplex by chemical approach2015
- Author(s)
  Chao-da Xiao, Takumi Ishizuka, Yan Xu
- Organizer
  第42回国際核酸化学シンポジウム
- Place of Presentation
  あいめっせホール(兵庫県姫路市)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] To connect cell by DNA forming G-quadruplex2014
- Author(s)
  Hongshan LIU, Takumi ISHIZUKA, Yan XU
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学(名古屋市)
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] DNA四重鎖構造を解析する機能性プローブの開発2014
- Author(s)
  石塚匠, 徐岩
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス(愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 19F-labeled telomere RNA G-quadruplex structure2014
- Author(s)
  BAO Hongliang, ISHIZUKA Takumi, XU Yan
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス(愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] To connect cell by DNA forming G-quadruplex2014
- Author(s)
  LIU, Hongshan; ISHIZUKA Takumi; XU, Yan
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス(愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] DNA四重鎖構造を解析する機能性プローブの開発2014
- Author(s)
  石塚匠・徐岩
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス(愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] 19F-labeled telomere RNA G-quadruplex structure2014
- Author(s)
  BAO, Hongliang; ISHIZUKA Takumi; XU, Yan
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス(愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] Chromosome painting by using click chemistry: A light-up approach2013
- Author(s)
  Takumi Ishizuka, Yan Xu
- Organizer
  The 40th International Symposium on Nucleic Acids Chemistry(第40回国際核酸化学シンポジウム)
- Place of Presentation
  神奈川大学(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] クリック化学により染色体DNA のマルチカラーイメージング2013
- Author(s)
  劉　泓汕, 徐岩
- Organizer
  日本化学会第9３回春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス（滋賀県草津市）
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 19F を含むテロメアRNA 四重鎖の構造と安定性2013
- Author(s)
  鮑宏亮、徐岩
- Organizer
  日本化学会第93回春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス(滋賀県草津市)
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 19Fを含むテロメアRNA四重鎖の構造と安定性2013
- Author(s)
  鮑宏亮、徐岩
- Organizer
  日本化学会第93回春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス(滋賀県草津市)
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] クリック化学により染色体 DNA のマルチカラーイメージング2013
- Author(s)
  劉泓汕、徐岩
- Organizer
  日本化学会第93回春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス(滋賀県草津市)
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメア RNA 四重鎖の構造と安定性2013
- Author(s)
  楊潔、石塚匠、徐岩
- Organizer
  日本化学会第93回春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス(滋賀県草津市)
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] Chromosome painting by using click chemistry : A light-up approach2013
- Author(s)
  Takumi Ishizuka, Yan Xu
- Organizer
  The 40th International Symposium on Nucleic Acids Chemistry(第40回国際核酸化学シンポジウム)
- Place of Presentation
  神奈川大学(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Chromosome painting by using click chemistry : A light-up approach2013
- Author(s)
  Takumi Ishizuka, Yan Xu
- Organizer
  第40回国際核酸化学シンポジウム(The 40th International Symposium on Nucleic Acids Chemistry)
- Place of Presentation
  立命館大学びわこ・くさつキャンパス(滋賀県草津市)
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] Structure and Biological Function of Telomere RNA2012
- Author(s)
  徐岩
- Organizer
  第39回国際核酸化学シンポジウム
- Place of Presentation
  名古屋大学豊田講堂(愛知県)
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 長鎖 DNA 中の四重鎖構造を検出する方法の開発2012
- Author(s)
  徐岩
- Organizer
  日本化学会第92 春季年会
- Place of Presentation
  慶應義塾大学(神奈川県)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] Structure and Biological Function of Telomere RNA2012
- Author(s)
  徐岩
- Organizer
  第39回国際核酸化学シンポジウム
- Place of Presentation
  名古屋大学豊田講堂(愛知県)
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] 可動式 DNA origami 構造体の pH センサーへの応用2012
- Author(s)
  徐岩
- Organizer
  日本化学会第92 春季年会
- Place of Presentation
  慶應義塾大学(神奈川県)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメアDNAとRNAによるハイブリッド四重鎖の形成およびその生化学機能2012
- Author(s)
  徐岩
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学高等教育推進機構
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] Structure and Biological Function of Telomere RNA2012
- Author(s)
  徐岩
- Organizer
  第39回国際核酸化学シンポジウム
- Place of Presentation
  名古屋大学豊田講堂(愛知県)
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] ヒトテロメアDNAとRNAによるハイブリッド四重鎖の形成およびその生化学機能2012
- Author(s)
  徐岩
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学高等教育推進機構
- Data Source
  KAKENHI-PROJECT-24651264
[Presentation] ヒトテロメア DNA と RNA によるハイブリッド四重鎖の形成およびその生化学機能2012
- Author(s)
  徐岩
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学高等教育推進機構
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 可動式DNA origami構造体のpHセンサーへの応用2012
- Author(s)
  徐岩
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(神奈川県)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメアDNAとRNAによるハイブリッド四重鎖の形成およびその生化学機能2012
- Author(s)
  徐岩
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学高等教育推進機構
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 分子間 RNA4重鎖構造による遺伝子発現の調節2012
- Author(s)
  徐岩
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(神奈川県)
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 分子間RNA4重鎖構造による遺伝子発現の調節2012
- Author(s)
  徐岩
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(神奈川県)
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 長鎖DNA中の四重鎖構造を検出する方法の開発2012
- Author(s)
  徐岩
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(神奈川県)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ARCUT による単一染色体のテロメア長測定2011
- Author(s)
  石塚匠、伊藤健一郎、徐岩、小宮山眞
- Organizer
  日本化学会第91回春季年会
- Place of Presentation
  神奈川大学横浜キャンパス(神奈川県)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] To Reveal Telomere's Mysterious by Chemical Approaches2011
- Author(s)
  徐岩
- Organizer
  Third International Symposium for Young Organic Chemists(3rd ISYOC)
- Place of Presentation
  物質・材料研究機構並木地区(茨城県)
- Year and Date
  2011-03-03
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメアRNAの構造と生化学機能およびテロメアRNAを標的とする小分子の探索2011
- Author(s)
  徐岩
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメアRNAの構造と生化学機能について2011
- Author(s)
  徐岩
- Organizer
  日本化学会第91回春季年会
- Place of Presentation
  神奈川大学横浜キャンパス(神奈川県)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] To Reveal Telomere's Mysterious by Chemical Approaches2011
- Author(s)
  徐岩
- Organizer
  Third International Symposium for Young Organic Chemists (3rd ISYOC)
- Place of Presentation
  物質・材料研究機構並木地区(茨城県)
- Year and Date
  2011-03-03
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメア RNAの構造と生化学機能について2011
- Author(s)
  徐岩、小宮山眞
- Organizer
  日本化学会第91回春季年会
- Place of Presentation
  神奈川大学横浜キャンパス (神奈川県)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメアRNAの構造と生化学機能について2011
- Author(s)
  徐岩、小宮山眞
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(東日本大震災の影響で)(紙面・Web上での開催のみ)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] ヒトテロメア RNA の構造と生化学機能およびテロメア RNA を標的とする小分子の探索2011
- Author(s)
  徐岩
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] Translational regulation by intermolecular RNA G-quadruplex2010
- Author(s)
  K. Ito 、 YAN XU 、 M. Komiyama
- Organizer
  2010 環太平洋国際化学会議
- Place of Presentation
  ハワイコンベンションセンター
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] G-rich sequence-specific cleaving by PNA/DNA hybrid G-quadruplex formation2010
- Author(s)
  T. Ishizuka、 M. Komiyama、 YAN XU
- Organizer
  2010 環太平洋国際化学会議
- Place of Presentation
  ハワイコンベンションセンター
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメア四重鎖 RNA に結合する小分子の探索2010
- Author(s)
  菊池宏海、倉林香織、 Zeng Huaqiang、徐岩、小宮山眞
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場「エポカルつくば」(茨城県)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメア四重鎖RNAに結合する小分子の探索2010
- Author(s)
  徐岩
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場「エポカルつくば」(茨城県)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 化学的アプローチによるヒトテロメアRNA構造と機能の解析2010
- Author(s)
  徐岩
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場「エポカルつくば」(茨城県)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメア RNAの構造と生化学機能2010
- Author(s)
  徐岩、小宮山眞
- Organizer
  第12回日本RNA 学会年会
- Place of Presentation
  第12回日本RNA 学会年会
- Year and Date
  2010-07-29
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] ヒトテロメアRNAの構造と生化学機能2010
- Author(s)
  徐岩
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂
- Year and Date
  2010-07-29
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] ヒトテロメアRNAの構造と生化学機能2010
- Author(s)
  徐岩
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  学術総合センター(東京都)
- Year and Date
  2010-07-29
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] Elucidation of structure and function of human telomere DNA/RNA and development of novel human telomere-targeted approaches2010
- Author(s)
  徐岩
- Organizer
  2010環太平洋国際化学会議
- Place of Presentation
  ハワイコンベンションセンター
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 化学的アプローチによるヒトテロメアRNA構造と機能の解析2010
- Author(s)
  徐岩
- Organizer
  第4回バイオ関連化学合同シンポジウム
- Place of Presentation
  大阪大学
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 分子間 G-quadruplex 構造によるタンパク質発現制御2010
- Author(s)
  伊藤健一郎、徐岩、小宮山眞
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場「エポカルつくば」(茨城県)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] Elucidation of structure and function of human telomere DNA/RNA and development of novel human telomere-targeted approaches2010
- Author(s)
  徐岩
- Organizer
  2010 環太平洋国際化学会議
- Place of Presentation
  ハワイコンベンションセンター
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] 化学的アプローチによるヒトテロメア RNA 構造と機能の解析2010
- Author(s)
  徐岩、神長邦行、鈴木裕太、伊藤健一郎、石塚匠、木村貴、小宮山眞
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場「エポカルつくば」(茨城県)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22350071
[Presentation] シクログアノシンの四重鎖構造での影響
- Author(s)
  石塚匠，徐岩
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学理工学部船橋キャンパス(千葉県船橋市)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] 19F NMR for probing human telomere RNA G-quadruplex structure
- Author(s)
  BAO, Hongliang; ISHIZUKA, Takumi; XU, Yan
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学理工学部船橋キャンパス(千葉県船橋市)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] PNA/DNA Hybrid G-Quadruplex Formation as a Novel Approach
- Author(s)
  Takumi Ishizuka , Yan Xu , Makoto Komiyama
- Organizer
  ISNAC2012　第39回国際核酸化学シンポジウム
- Place of Presentation
  名古屋大学豊田講堂（愛知県）
- Year and Date
  2012-11-15 – 2012-11-17
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Cell-cell connection by multiple chemical approaches. The 41th International Symposium on Nucleic Acids Chemistry
- Author(s)
  LIU, Hongshan; ISHIZUKA, Takumi; XU, Yan
- Organizer
  第41回国際核酸化学シンポジウム
- Place of Presentation
  北九州国際会議場(福岡県北九州市)
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] 19F-NMRによるDNA四重鎖の構造変化の観測
- Author(s)
  石塚匠，徐岩
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山大学(岡山県岡山市)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Multiple chemical approaches control cell adhesion
- Author(s)
  LIU, Hongshan; ISHIZUKA, Takumi; XU, Yan
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学理工学部船橋キャンパス(千葉県船橋市)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] ヒトテロメアRNAの構造および生化学機能
- Author(s)
  徐岩，石塚匠，肖潮達，劉暁，夏岩，鮑宏亮，劉泓汕
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山大学(岡山県岡山市)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] To probe human telomere RNA Gquadruplex structure by 19F NMR
- Author(s)
  BAO, Hongliang; ISHIZUKA, Takumi; XU, Yan
- Organizer
  第41回国際核酸化学シンポジウム
- Place of Presentation
  北九州国際会議場(福岡県北九州市)
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Effects of 8,2'-O-cycloguanosine on G-quadruplex structure
- Author(s)
  Takumi Ishizuka, XU, Yan
- Organizer
  第41回国際核酸化学シンポジウム
- Place of Presentation
  北九州国際会議場(福岡県北九州市)
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] ヒトテロメアRNAの構造と生化学機能およびテロメアRNAを標的とする小分子の探索
- Author(s)
  徐　岩
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場（茨城）
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Recognition of telomere RNA Gquadruplex by small molecule
- Author(s)
  LIU, Xiao; ISHIZUKA, Takumi; XIAO, Chaoda; IIDA, Keisuke; NAGASAWA, Kazuo; XU, Yan
- Organizer
  第41回国際核酸化学シンポジウム
- Place of Presentation
  北九州国際会議場(福岡県北九州市)
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26288083
[Presentation] Macrocyclic Polyoxazoles as telomere RNA and DNA G-Quadruplexbinding Ligands
- Author(s)
  LIU, Xiao; ISHIZUKA, Takumi; XIAO, Chaoda; IIDA, Keisuke; NAGASAWA, Kazuo; XU, Yan
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学理工学部船橋キャンパス(千葉県船橋市)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26288083

1. KOMIYAMA Makoto (50133096)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. SUMAOKA Jun (10280934)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SHIGI Narumi (00396780)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Hirai Toshinori (40274724)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NANASHIMA ATSUSHI (60380838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 石塚匠 (50700085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 片岡寛章 (10214321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 東美菜子 (00643389)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 菱川善隆 (60304276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 松本仁 (90363572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 横谷篤至 (00183989)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. ITO Yasuhiro (50508108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. HIGUCHI Maiko (30420235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. AIBA Yuichiro (10581085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Tanaka Makiko (90397703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Rajendran Arivazhagan (90723122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 林哲也 (10173014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 水谷陽一 (40599586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 山口優也 (60779966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 甲斐健吾 (90851585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 池ノ上実 (40612370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 佐藤裕之 (20545404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KUZUYA Akinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 小宮山真

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
25. 實吉尚郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 山本泰彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 大吉崇文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 長澤和夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 寺正行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

XU YAN 徐 岩

XU Yan 徐 岩

Research Projects

Research Products

Co-Researchers

Chemical Biology Aimed at Elucidating the Structure, Function, and Interaction with Proteins of Non-canonical Nucleic AcidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

クリック反応技術と軸配位子糖鎖連結ポルフィリン錯体を融合した革新的PDTの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

19F NMR分子技術の開発によるヒト細胞内DNA及びRNA高次構造の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Innovative Cancer MRI Imaging Techniques Using New Contrast Agents Based on Molecular Binding Technology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分子結合技術を用いた造影剤による革新的がんCT画像化技術の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the enhanced effect and less invasiveness of new photodynamic therapy for bilie duct carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structure and reactivity of human telomere RNA and development of new cancer therapy for targeting telomerePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation of new genome science using chemical tools to precisely detect modification and damage of human genome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemical biology for elucidation of molecular basis of telomeric RNA G-quadruplex structurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of visualization technique of cancer cell by click chemistryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure elucidation of human telomeric DNA and RNA in cells by chemical approach and its applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation of genome manipulation technology using super restriction enzyme

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Oligonucleotide Containing 8-Trifluoromethyl-2′-Deoxyguanosine as a Z-DNA Probe. In: Kim, K.K., Subramani, V.K. (eds) Z-DNA.2023

Author(s)

Total Pages

XU YAN 徐岩

XU Yan 徐岩