Saino Hiromichi 齊野廣道

… Alternative Names

SAINO Hiromichi 齊野廣道

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Researcher Number	40525549
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 青山学院大学, 理工学部, 助教 2015 – 2016: 青山学院大学, 理工学部, 助教 2013: 青山学院大学, 理工学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) Except Principal Investigator Structural biochemistry
Keywords	Principal Investigator OXA-58 / アシネトバクター / 抗菌薬 / ラクタマーゼ / カルバペネム / 多剤耐性菌 / X線結晶構造解析 / 酵素 / 薬剤耐性 Except Principal Investigator 脂質 … More / 炎症 / X線結晶構造解析 / ロイコトリエン / 界面活性剤 / 結晶化 / Ｘ線結晶構造解析 / 膜タンパク質 Less

薬剤耐性クラスD β-ラクタマーゼのカルバペネム加水分解触媒機構Principal Investigator
- Principal Investigator
  
  齊野廣道
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Aoyama Gakuin University
Insights into Mobility and Stability of the OXA-58 Carbapenemase Structure with the N-zeta-Carboxylated Catalytic Residue Lysine.Principal Investigator
- Principal Investigator
  
  Saino Hiromichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Aoyama Gakuin University
Crystal structure determination of microsomal prostaglandin E2 synthase 1 with the open active site.
- Principal Investigator
  
  AGO Hideo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2016 2015 2013 2011

All Journal Article Presentation

[Journal Article] Crystal Structure of OXA-58 with the Substrate-Binding Cleft in a Closed State: Insights into the Mobility and Stability of the OXA-58 Structure2015
- Author(s)
  Hiromichi Saino, Tomohiro Sugiyabu, Go Ueno, Masaki Yamamoto, Yoshikazu Ishii, Masashi Miyano
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 12 Pages: e0145869-e0145869
- DOI
  10.1371/journal.pone.0145869
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21356, KAKENHI-PROJECT-25461524
[Journal Article] A leukotriene C4 synthase inhibitor with the backbone of 5-(5-methylene-4-oxo-4,5-dihydrothiazol-2-ylamino) isophthalic acid2013
- Author(s)
  Ago, H. Okimoto, N. Kanaoka, Y. Morimoto, G. Ukita, Y. Saino, H. Taiji, M. Miyano, M.
- Journal Title
  
  journal of biochemistry
  
  Volume: in press Issue: 5 Pages: 421-429
- DOI
  10.1093/jb/mvt007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570153
[Journal Article] The Catalytic Architecture of Leukotriene C4 Synthase with Two Arginine Residues2011
- Author(s)
  Saino, Hiromichi Ukita, Yoko Ago, Hideo Irikura, Daisuke Nisawa, Atsushi Ueno, Go Yamamoto, Masaki Kanaoka, Yoshihide Lam, Bing K. Austen, K. Frank Miyano, Masashi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 16392-16401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570153
[Journal Article] Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-β-D-selenomaltoside.2011
- Author(s)
  Saino Hiromichi, Ago Hideo, Ukita Yoko, Miyano Masashi.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun.
  
  Volume: 67 Pages: 1666-1673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570153
[Presentation] カルバペネム耐性 β-ラクタマーゼ OXA-58 のカルバペネム分解機構2016
- Author(s)
  齊野廣道・杉籔智大・石井良和・宮野雅司
- Organizer
  日本結晶学会平成28年度年会
- Place of Presentation
  水戸
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K21356
[Presentation] カルバペネム耐性 β-ラクタマーゼ OXA-58 を活性化・熱安定する活性残基リジン-カルボキシ修飾の構造基盤2015
- Author(s)
  杉藪智大・石井良和・宮野雅司・齊野廣道
- Organizer
  日本結晶学会
- Place of Presentation
  大阪府立大学中百舌鳥キャンパス
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K21356

1. AGO Hideo (70360477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Saino Hiromichi 齊野 廣道

SAINO Hiromichi 齊野 廣道

Research Projects

Research Products

Co-Researchers

薬剤耐性クラスD β-ラクタマーゼのカルバペネム加水分解触媒機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Insights into Mobility and Stability of the OXA-58 Carbapenemase Structure with the N-zeta-Carboxylated Catalytic Residue Lysine.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Crystal structure determination of microsomal prostaglandin E2 synthase 1 with the open active site.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Crystal Structure of OXA-58 with the Substrate-Binding Cleft in a Closed State: Insights into the Mobility and Stability of the OXA-58 Structure2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A leukotriene C4 synthase inhibitor with the backbone of 5-(5-methylene-4-oxo-4,5-dihydrothiazol-2-ylamino) isophthalic acid2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Catalytic Architecture of Leukotriene C4 Synthase with Two Arginine Residues2011

Author(s)

Journal Title

Data Source

[Journal Article] Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-β-D-selenomaltoside.2011

Author(s)

Journal Title

Data Source

[Presentation] カルバペネム耐性 β-ラクタマーゼ OXA-58 のカルバペネム分解機構2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] カルバペネム耐性 β-ラクタマーゼ OXA-58 を活性化・熱安定する活性残基リジン-カルボキシ修飾の構造基盤2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Saino Hiromichi 齊野廣道

SAINO Hiromichi 齊野廣道