Sadatomo Ai 佐田友藍

Researcher Number	40528585
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 自治医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 腫瘍関連マクロファージ / 腫瘍浸潤リンパ球 / 免疫応答 / 免疫チェックポイント分子 / 細胞運動 / CXCL-11 / ケモタキシス / T細胞 / マクロファージ / 好中球細胞外トラップ … More Except Principal Investigator … More 転移 / 糖尿病 / 好中球細胞外トラップ / 大腸癌 / 発がん / 胃癌 / 腫瘍浸潤リンパ球 / 腹膜播種 / 膵癌 / 発癌 / 多重免疫染色 / メトホルミン / 免疫 / フェロトーシス / 化学放射線療法耐性 / 直腸癌 / 再発 / 上部消化管癌 / 大網 / 腹腔内マクロファージ / がん免疫微小環境 / 肝転移 / 大網乳班 / T細胞 / マクロファージ / 腹腔免疫 / 大腸乳斑 / コリン作動性シグナル / 迷走神経 / 質量分析 / 免疫逃避 / トロゴサイトーシス / 接着分子 / リンパ球 / がん転移 / トルゴサイトーシス / 薬物動態 / 免疫療法 / 腹腔内投与 / 抗PD-1抗体 / 免疫チェックポイント / フィブロネクチン / 骨髄由来抑制性細胞 / 抗PD-１抗体 / 免疫チェックポイント阻害 Less

化学放射線療法耐性直腸癌に対するフェロトーシス誘導療法の開発
- Principal Investigator
  
  井上賢之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Jichi Medical University
Role of neutrophil extracellular traps in the pathophysiology of colorectal cancer
- Principal Investigator
  
  鯉沼広治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University
Role of neutrophil extracellular traps on pathophysiology of diabetes-associated cancer
- Principal Investigator
  
  佐田尚宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University
Role of trogositosis in tumor immune escape
- Principal Investigator
  
  Saito Shin
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jichi Medical University
Oncological significance of vagotomy in upper gastrointestinal surgery
- Principal Investigator
  
  Hosoya Yoshinori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University
Development of intraperitoneal immunotherapy for peritoneal metastasis
- Principal Investigator
  
  Yamaguchi Hironori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jichi Medical University
Neutrophil extracellular trap and immune response in gastrointestinal tumorPrincipal Investigator
- Principal Investigator
  
  Sadatomo Ai
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Activated neutrophils inhibit chemotactic migration of activated T lymphocytes to CXCL11 by multiple mechanisms.2023
- Author(s)
  Tamura Kohei、Miyato Hideyo、Kanamaru Rihito、Sadatomo Ai、Takahashi Kazuya、Ohzawa Hideyuki、Koyanagi Takahiro、Saga Yasushi、Takei Yuji、Fujiwara Hiroyuki、Lefor Alan Kawarai、Sata Naohiro、Kitayama Joji.
- Journal Title
  
  Cellular Immunology
  
  Volume: 384 Pages: 104663-104663
- DOI
  10.1016/j.cellimm.2023.104663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24411
[Journal Article] Peripheral low-density granulocytes after colorectal cancer surgery in predicting recurrence2023
- Author(s)
  Futoh Yurie、Kumagai Yuko、Miyato Hideyo、Ozawa Hideyuki、Kanamaru Rihito、Sadatomo Ai、Ohnishi Yasuharu、Koinuma Koji、Horie Hisanaga、Yamaguchi Hironori、Lefor Alan Kawarai、Sata Naohiro、Kitayama Joji
- Journal Title
  
  BJS Open
  
  Volume: 7 Issue: 1 Pages: 7832-7832
- DOI
  10.1093/bjsopen/zrac154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17629, KAKENHI-PROJECT-21K16432, KAKENHI-PROJECT-21K20958, KAKENHI-PROJECT-21K08602, KAKENHI-PROJECT-22K16543
[Journal Article] Neutrophil extracellular traps (NETs) reduce the diffusion of doxorubicin which may attenuate its ability to induce apoptosis of ovarian cancer cells2022
- Author(s)
  Tamura Kohei、Miyato Hideyo、Kanamaru Rihito、Sadatomo Ai、Takahashi Kazuya、Ohzawa Hideyuki、Koyanagi Takahiro、Saga Yasushi、Takei Yuji、Fujiwara Hiroyuki、Lefor Alan Kawarai、Sata Naohiro、Kitayama Joji
- Journal Title
  
  Heliyon
  
  Volume: 8 Issue: 6 Pages: e09730-e09730
- DOI
  10.1016/j.heliyon.2022.e09730
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17629, KAKENHI-PROJECT-21K16432, KAKENHI-PROJECT-23K24411
[Journal Article] NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury2020
- Author(s)
  Ito Homare、Kimura Hiroaki、Karasawa Tadayoshi、Hisata Shu、Sadatomo Ai、Inoue Yoshiyuki、Yamada Naoya、Aizawa Emi、Hishida Erika、Kamata Ryo、Komada Takanori、Watanabe Sachiko、Kasahara Tadashi、Suzuki Takuji、Horie Hisanaga、Kitayama Joji、Sata Naohiro、Yamaji-Kegan Kazuyo、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 205 Issue: 5 Pages: 1393-1405
- DOI
  10.4049/jimmunol.2000217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K08630, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290, KAKENHI-PROJECT-20K17629, KAKENHI-PROJECT-17K09889
[Presentation] 大腸癌患者の術後末梢血中低比重好中球と予後の関連性2022
- Author(s)
  風當ゆりえ, 北山丈二, 金子勇貴, 髙橋和也, 木村勇希, 太田学, 熊谷祐子, 太白健一, 直井大志, 佐田友藍, 井上賢之, 大澤英之, 宮戸秀世, 鯉沼広治, 佐久間康成, 堀江久永, 細谷好則,佐田尚宏
- Organizer
  第77回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08901
[Presentation] 大腸がん患者の術直後の血中低比重好中球比率が補助化学療法の再発予測因子となるか2022
- Author(s)
  風當ゆりえ, 北山丈二, 金子勇貴, 高橋和也, 木村有希, 熊谷祐子, 太白健一, 直井大志, 佐田友藍, 大澤英之, 宮戸秀世, 鯉沼広治, 堀江久永, 山口博紀,佐田尚宏
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08901
[Presentation] 大腸がん患者の術直後の血中低比重好中球比率が補助化学療法の再発予測因子となるか2022
- Author(s)
  風當ゆりえ, 北山丈二, 金子勇貴, 高橋和也, 木村有希, 熊谷祐子, 太白健一, 直井大志, 佐田友藍, 大澤英之, 宮戸秀世, 鯉沼広治, 堀江久永, 山口博紀,佐田尚宏
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17629
[Presentation] 大腸癌患者の術後末梢血中低比重好中球と予後の関連性2022
- Author(s)
  風當ゆりえ, 北山丈二, 金子勇貴, 髙橋和也, 木村勇希, 太田学, 熊谷祐子, 太白健一, 直井大志, 佐田友藍, 井上賢之, 大澤英之, 宮戸秀世, 鯉沼広治, 佐久間康成, 堀江久永, 細谷好則,佐田尚宏
- Organizer
  第77回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17629
[Presentation] PMA刺激好中球が癌細胞の遊走能に与える影響2021
- Author(s)
  髙橋和也, 大澤英之, 金子勇貴, 田村昂平, 木村有希, 齋藤晶, 東條峰之, 金子理人, 佐田友藍, 宮戸秀世, 佐田尚宏，北山丈二
- Organizer
  第80回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17629
[Presentation] 活性化好中球は活性化T細胞の遊走能を抑制する2021
- Author(s)
  田村昂平, 金子勇貴, 風當ゆりえ, 髙橋和也, 木村有希, 齋藤晶, 東條峰之, 金丸理人, 佐田友藍, 宮戸秀世, 大澤英之, 嵯峨泰, 竹井裕二, 藤原寛行，北山丈二
- Organizer
  第80回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17629
[Presentation] 当院における内視鏡摘除後のT1直腸癌追加腸切除適応症例についての検討2020
- Author(s)
  巷野佳彦, 堀江久永, 津久井秀則, 本間祐子, 熊谷祐子, 東條峰之, 佐田友藍, 清水徹一郎, 直井大志, 田原真紀子, 伊藤誉, 井上賢之, 鯉沼広治, 佐久間康成, 細谷好則, 味村俊樹, 北山丈二, 佐田尚宏
- Organizer
  日本大腸肛門病学会雑誌
- Data Source
  KAKENHI-PROJECT-20K17629
[Presentation] 当科における下部直腸癌に対するtaTMEの導入と短期治療成績2020
- Author(s)
  田原真紀子, 堀江久永, 佐田友藍, 直井大志, 巷野佳彦, 鯉沼広治, 味村俊樹, 細谷好則, 北山丈二, 佐田尚宏
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K17629

1. 北山丈二 (20251308)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
2. 宮戸秀世 (90813163)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. Yamaguchi Hironori (20376445)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 堀江久永 (20316532)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. Saito Shin (60382909)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 相澤健一 (70436484)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 倉科憲太郎 (70382900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 井上賢之 (80375279)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 金丸理人 (10625544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. Hosoya Yoshinori (30275698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 伊藤大知 (50447421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐久間康成 (10296105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高橋将文 (40296108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 山田直也 (50611787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 鯉沼広治 (20382905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 佐田尚宏 (20261977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 園田洋史 (80770205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 木村博昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 唐澤直義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 渡邊幸子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 鎌田諒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sadatomo Ai 佐田友 藍

Research Projects

Research Products

Co-Researchers

化学放射線療法耐性直腸癌に対するフェロトーシス誘導療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of neutrophil extracellular traps in the pathophysiology of colorectal cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of neutrophil extracellular traps on pathophysiology of diabetes-associated cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of trogositosis in tumor immune escape

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Oncological significance of vagotomy in upper gastrointestinal surgery

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of intraperitoneal immunotherapy for peritoneal metastasis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neutrophil extracellular trap and immune response in gastrointestinal tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Activated neutrophils inhibit chemotactic migration of activated T lymphocytes to CXCL11 by multiple mechanisms.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peripheral low-density granulocytes after colorectal cancer surgery in predicting recurrence2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neutrophil extracellular traps (NETs) reduce the diffusion of doxorubicin which may attenuate its ability to induce apoptosis of ovarian cancer cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 大腸癌患者の術後末梢血中低比重好中球と予後の関連性2022

Author(s)

Organizer

Data Source

[Presentation] 大腸がん患者の術直後の血中低比重好中球比率が補助化学療法の再発予測因子となるか2022

Author(s)

Organizer

Data Source

[Presentation] 大腸がん患者の術直後の血中低比重好中球比率が補助化学療法の再発予測因子となるか2022

Author(s)

Organizer

Data Source

[Presentation] 大腸癌患者の術後末梢血中低比重好中球と予後の関連性2022

Author(s)

Sadatomo Ai 佐田友藍