Kinoshita Masanao 木下祥尚

Researcher Number	40529517
Other IDs
Affiliation (Current)	2025: 群馬大学, 大学院理工学府, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 九州大学, 理学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Biophysics Except Principal Investigator Medium-sized Section 37:Biomolecular chemistry and related fields
Keywords	Principal Investigator 脂質ラフト / 蛍光相関分光法 / 脂質膜 / 共焦点顕微鏡 / 膜タンパク質 / 生体膜 / 蛍光脂質 / 蛍光分光法 / 神経芽腫細胞 / 蛍光共鳴エネルギー移動 … More / 細胞膜 / 蛍光分光測定 / 蛍光脂質プローブ / 局所麻酔薬 / ナノ領域 / 電子顕微鏡 / ナノ構造 / 人工膜 / 脂質充填構造 / 相分離 / 炭素鎖充填構造 / 電子線散乱 … More Except Principal Investigator 脂質ケミカルバイオロジー / 金ナノ粒子 / バクテリオロドプシン / KcsA / 表面プラズモン共鳴 / ケミカルバイオロジー / 相互作用 / 膜タンパク質 / 脂質 Less

脂質ラフトに対する膜タンパク質取り込みの機序とシャペロン仮説の実証Principal Investigator
- Principal Investigator
  
  木下祥尚
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyushu University
Lipid raft-based mechanism of the local anesthetic actionPrincipal Investigator
- Principal Investigator
  
  Kinoshita Masanao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyushu University
Establishment of research base for lipid chemical biology
- Principal Investigator
  
  松森信明
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyushu University
Development of electron nano-diffraction for the study on membrane structuresPrincipal Investigator
- Principal Investigator
  
  Kinoshita Masanao
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyushu University

All 2025 2024 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Gold nanoparticle-powered screening of membrane protein-specific lipids from complex lipid mixtures2024
- Author(s)
  Wangamnuayporn Supakorn、Kinoshita Masanao、Kawai Takayuki、Matsumori Nobuaki
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 687 Pages: 115447-115447
- DOI
  10.1016/j.ab.2023.115447
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18950, KAKENHI-PROJECT-22K19115, KAKENHI-PLANNED-21H05092, KAKENHI-PROJECT-20H00405
[Journal Article] Inimitable Impacts of Ceramides on Lipid Rafts Formed in Artificial and Natural Cell Membranes2022
- Author(s)
  Kinoshita Masanao、Matsumori Nobuaki
- Journal Title
  
  Membranes
  
  Volume: 12 Issue: 8 Pages: 727-727
- DOI
  10.3390/membranes12080727
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19115, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-20K06590
[Journal Article] Behavior of Triterpenoid Saponin Ginsenoside Rh2 in Ordered and Disordered Phases in Model Membranes Consisting of Sphingomyelin, Phosphatidylcholine, and Cholesterol2022
- Author(s)
  Garza Darcy Lacanilao、Hanashima Shinya、Umegawa Yuichi、Murata Michio、Kinoshita Masanao、Matsumori Nobuaki、Greimel Peter
- Journal Title
  
  Langmuir
  
  Volume: 38 Issue: 34 Pages: 10478-10491
- DOI
  10.1021/acs.langmuir.2c01261
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19115, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-21H04707, KAKENHI-PROJECT-19K05713
[Journal Article] 脂質ラフトを標的とする局所麻酔薬の作用機序2022
- Author(s)
  木下祥尚, 松森信明
- Journal Title
  
  Medical Science Digest
  
  Volume: 48 Pages: 50-51
- Data Source
  KAKENHI-PROJECT-20H00405
[Journal Article] Impact of sphingomyelin acyl chain heterogeneity upon properties of raft-like membranes2022
- Author(s)
  Hirano Kana、Kinoshita Masanao、Matsumori Nobuaki
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1864 Issue: 12 Pages: 184036-184036
- DOI
  10.1016/j.bbamem.2022.184036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19115, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-20K06590
[Journal Article] Formation of a Tight Complex between Amphidinol 3 and Sterols in Lipid Bilayers Revealed by Short-Range Energy Transfer2022
- Author(s)
  Hieda Manami、Tsujimura Koya、Kinoshita Masanao、Matsumori Nobuaki
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 95 Issue: 12 Pages: 1753-1759
- DOI
  10.1246/bcsj.20220273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19115, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-20K06590
[Journal Article] Molecular substructure of the liquid-ordered phase formed by sphingomyelin and cholesterol: sphingomyelin clusters forming nano-subdomains are a characteristic feature2022
- Author(s)
  Murata Michio、Matsumori Nobuaki、Kinoshita Masanao、London Erwin
- Journal Title
  
  Biophysical Reviews
  
  Volume: 14 Issue: 3 Pages: 655-678
- DOI
  10.1007/s12551-022-00967-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19115, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-21H04707
[Journal Article] Metal complex lipids for fluid-fluid phase separation in co‐assembled phospholipid membranes2021
- Author(s)
  Ohtani Ryo、Anegawa Yuka、Watanabe Hikaru、Tajima Yutaro、Kinoshita Masanao、Matsumori Nobuaki、Kawano Kenichi、Yanaka Saeko、Kato Koichi、Nakamura Masaaki、Ohba Masaaki、Hayami Shinya
- Journal Title
  
  Angewandte Chemie
  
  Volume: - Issue: 24 Pages: 13715-13720
- DOI
  10.1002/ange.202102774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00405
[Journal Article] Preparation of Nitrogen Analogues of Ceramide and Studies of Their Aggregation in Sphingomyelin Bilayers2021
- Author(s)
  Yasuda Hiroki、Torikai Kohei、Kinoshita Masanao、Sazzad Md. Abdullah Al、Tsujimura Koya、Slotte J. Peter、Matsumori Nobuaki
- Journal Title
  
  Langmuir
  
  Volume: 37 Issue: 42 Pages: 12438-12446
- DOI
  10.1021/acs.langmuir.1c02101
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-18K05462
[Journal Article] 脂質ラフトをターゲットとする局所麻酔薬の作用機序2021
- Author(s)
  木下祥尚　松森信明
- Journal Title
  
  Medical Science Digest
  
  Volume: 48 Pages: 50-51
- Data Source
  KAKENHI-PROJECT-20K06590
[Journal Article] Amphidinol 3 preferentially binds to cholesterol in disordered domains and disrupts membrane phase separation2021
- Author(s)
  Hieda Manami、Sorada Akira、Kinoshita Masanao、Matsumori Nobuaki
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 26 Pages: 100941-100941
- DOI
  10.1016/j.bbrep.2021.100941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-20H00405
[Journal Article] Low-flux scanning electron diffraction reveals substructures inside the ordered membrane domain2020
- Author(s)
  Kinoshita Masanao、Yamaguchi Shimpei、Matsumori Nobuaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 22188-22188
- DOI
  10.1038/s41598-020-79083-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-20H00405
[Journal Article] The influence of ceramide and its dihydro analog on the physico-chemical properties of sphingomyelin bilayers2020
- Author(s)
  Kinoshita Masanao、Tanaka Kaoru、Matsumori Nobuaki
- Journal Title
  
  Chemistry and Physics of Lipids
  
  Volume: 226 Pages: 104835-104835
- DOI
  10.1016/j.chemphyslip.2019.104835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19149, KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-20H00405
[Journal Article] Pseudo‐Membrane Jackets: Two‐Dimensional Coordination Polymers Achieving Visible Phase Separation in Cell Membrane2020
- Author(s)
  Ohtani Ryo、Kawano Kenichi、Kinoshita Masanao、Yanaka Saeko、Watanabe Hikaru、Hirai Kenji、Futaki Shiroh、Matsumori Nobuaki、Uji‐i Hiroshi、Ohba Masaaki、Kato Koichi、Hayami Shinya
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 59 Issue: 41 Pages: 17931-17937
- DOI
  10.1002/anie.202006600
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04701, KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-17H03003, KAKENHI-PROJECT-18K14245, KAKENHI-PLANNED-16H06519
[Journal Article] Assembly formation of minor dihydrosphingomyelin in sphingomyelin-rich ordered membrane domains2020
- Author(s)
  Kinoshita Masanao、Kyo Takumi、Matsumori Nobuaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 11794-11794
- DOI
  10.1038/s41598-020-68688-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-20H00405
[Journal Article] Defining raft domains in the plasma membrane2019
- Author(s)
  Akihiro Kusumi、Takahiro K. Fujiwara、Taka A. Tsunoyama、Rinshi S. Kasai、An‐An Liu、Koichiro M. Hirosawa、Masanao Kinoshita、Nobuaki Matsumori、Naoko Komura、Hiromune Ando、Kenichi G. N. Suzuki
- Journal Title
  
  Traffic
  
  Volume: 21 Issue: 1 Pages: 106-137
- DOI
  10.1111/tra.12718
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23627, KAKENHI-PUBLICLY-18H04671, KAKENHI-PLANNED-18H05424, KAKENHI-PROJECT-17H03666, KAKENHI-PROJECT-18H02401, KAKENHI-PROJECT-17K07333, KAKENHI-PROJECT-18K19149, KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-18H03942, KAKENHI-PROJECT-20H00405
[Journal Article] Archaeal Glycolipid S-TGA-1 Is Crucial for Trimer Formation and Photocycle Activity of Bacteriorhodopsin2019
- Author(s)
  Inada Masataka、Kinoshita Masanao、Matsumori Nobuaki
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 15 Issue: 1 Pages: 197-204
- DOI
  10.1021/acschembio.9b00756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19149, KAKENHI-PUBLICLY-20H04781, KAKENHI-PROJECT-20H00405
[Presentation] Electron diffraction reveals substructures in lipid raft-like ordered membrane domains2025
- Author(s)
  Masanao Kinoshita, Mayu Maeda, Shimpei Yamaguchi, Nobuaki Matsumori
- Organizer
  International Union for Pure and Applied Biophysics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05719
[Presentation] Impact of sphingomyelin acyl chain heterogeneity upon properties of raft-like membranes2024
- Author(s)
  木下祥尚, 平野佳奈, 松森信明
- Organizer
  日本生物物理学会
- Data Source
  KAKENHI-PROJECT-23K05719
[Presentation] 局所麻酔剤が細胞膜に形成される特異的膜領域「脂質ラフト」に及ぼす影響2021
- Author(s)
  田中康裕、木下祥尚、松森信明
- Organizer
  日本化学会第101回年会
- Data Source
  KAKENHI-PROJECT-20K06590
[Presentation] Effects of local anesthetics on lipid rafts formed in live cell-membranes2021
- Author(s)
  Yasuhiro Tanaka, Masanao Kinoshita, Nobuaki Matsumori
- Organizer
  日本化学会第101回年会
- Data Source
  KAKENHI-PROJECT-20K06590
[Presentation] 低流量電子線散乱法を用いた局所的な脂質充填構造の解析2020
- Author(s)
  木下　祥尚
- Organizer
  日本化学会年会
- Data Source
  KAKENHI-PROJECT-17K15107

1. 松森信明 (50314357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 老木成稔 (10185176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 岩本真幸 (40452122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 神田大輔 (80186618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 河村奈緒子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 大谷亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 川井隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kinoshita Masanao 木下 祥尚

Research Projects

Research Products

Co-Researchers

脂質ラフトに対する膜タンパク質取り込みの機序とシャペロン仮説の実証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Lipid raft-based mechanism of the local anesthetic actionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of research base for lipid chemical biology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of electron nano-diffraction for the study on membrane structuresPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gold nanoparticle-powered screening of membrane protein-specific lipids from complex lipid mixtures2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inimitable Impacts of Ceramides on Lipid Rafts Formed in Artificial and Natural Cell Membranes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Behavior of Triterpenoid Saponin Ginsenoside Rh2 in Ordered and Disordered Phases in Model Membranes Consisting of Sphingomyelin, Phosphatidylcholine, and Cholesterol2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 脂質ラフトを標的とする局所麻酔薬の作用機序2022

Author(s)

Journal Title

Data Source

[Journal Article] Impact of sphingomyelin acyl chain heterogeneity upon properties of raft-like membranes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Formation of a Tight Complex between Amphidinol 3 and Sterols in Lipid Bilayers Revealed by Short-Range Energy Transfer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular substructure of the liquid-ordered phase formed by sphingomyelin and cholesterol: sphingomyelin clusters forming nano-subdomains are a characteristic feature2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metal complex lipids for fluid-fluid phase separation in co‐assembled phospholipid membranes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preparation of Nitrogen Analogues of Ceramide and Studies of Their Aggregation in Sphingomyelin Bilayers2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 脂質ラフトをターゲットとする局所麻酔薬の作用機序2021

Author(s)

Journal Title

Data Source

[Journal Article] Amphidinol 3 preferentially binds to cholesterol in disordered domains and disrupts membrane phase separation2021

Author(s)

Journal Title

DOI

Kinoshita Masanao 木下祥尚

[Presentation] 局所麻酔剤が細胞膜に形成される特異的膜領域「脂質ラフト」に及ぼす影響2021