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Urasaki Akihiro  浦崎 明宏

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… Alternative Names

SAKUMURA Yuichi  作村 諭一

浦崎 明宏  ウラサキ アキヒロ

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Researcher Number 40550083
Other IDs
Affiliation (Current) 2025: 神戸大学, 科学技術イノベーション研究科, 特命准教授
2025: 神戸大学, 先端バイオ工学研究センター, 特命准教授
Affiliation (based on the past Project Information) *help 2023: 神戸大学, 先端バイオ工学研究センター, 特命准教授
2023: 京都府立医科大学, 医学部, 研究員
2019 – 2022: 国立研究開発法人国立循環器病研究センター, 研究所, 室長
2016: 愛知県立大学, 情報科学研究科, 准教授
2014 – 2016: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教
2010: National Institute of Genetics, 研究員
2009: National Institute of Genetics, 個体遺伝研究系, 博士研究員
Review Section/Research Field
Principal Investigator
Basic Section 48010:Anatomy-related / Developmental biology / Molecular biology
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 52:General internal medicine and related fields / Basic Section 48010:Anatomy-related / Neurophysiology / General neuroscience
Keywords
Principal Investigator
ゼブラフィッシュ / 遺伝性出血性末梢血管拡張症 / ACVRL1 / 血管形成 / オスラー病 / 遺伝性出血性末梢血管拡張症(HHT) / 消化管血管形成 / ALK1シグナル / acvrl1 / マウス … More / 脈管 / 発生 / 血管 / 組織形成 / shootin1 / 遺伝子トラップ / 後主静脈 / mekk3 … More
Except Principal Investigator
心血管発生 / 先天性心疾患 / 心筋細胞 / 内皮細胞 / シグナル伝達 / 遺伝子組換えマウス / 遺伝性血管病 / 先天性心血管疾患 / 遺伝子発現制御 / 血管病 / Notch/Rbpjシグナル伝達経路 / 心室筋 / 細胞系譜 / 転写 / 心筋 / エンハンサー / 転写制御 / 細胞分化 / 発生 / 胸部大血管 / 心臓 / 難治性血管病 / 形態形成 / 細胞シグナル伝達 / TGF-β / SMAD4 / endoglin / SMAD / BMPシグナル / Smad / BMP9 / ALK1 / ACVRL1 / 遺伝性出血性末梢血管拡張症 / 大脳皮質形成 / メカノバイオロジー / ゼブラフィッシュ / ノックアウトマウス / 大脳組織形成 / Shootin Less
  • Research Projects

    (11 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (21 People)
  •  心臓発生期のゲノム網羅的エンハンサーアトラスと心臓内領域特異的遺伝子発現制御機構

    • Principal Investigator
      中川 修
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      National Cardiovascular Center Research Institute
  •  ALK1シグナルの臓器特異的血管形成における意義と難治性血管疾患の発症メカニズムPrincipal Investigator

    • Principal Investigator
      浦崎 明宏
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Kobe University
      National Cardiovascular Center Research Institute
  •  Downstream genes of signaling pathways implicated in human cardiovascular diseases: in vivo significance and regulatory mechanisms

    • Principal Investigator
      中川 修
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Integrated analysis of pathgenesis of hereditary hemorrhagic telangiectasia

    • Principal Investigator
      Iwasa Toru
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Role of vascular interaction in embryonic developmentPrincipal Investigator

    • Principal Investigator
      Urasaki Akihiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Molecular mechanisms of cell differentiation during development of great vessels and ventricles

    • Principal Investigator
      Watanabe Yusuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Significance of cellular signaling pathways in cardiovascular development and disease

    • Principal Investigator
      NAKAGWA Osamu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Functional analysis of shootin1 during zebrafish tissue morphogenesisPrincipal Investigator

    • Principal Investigator
      Urasaki Akihiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Developmental biology
    • Research Institution
      Nara Institute of Science and Technology
  •  Mechanical and pathological analyses of shootin-mediated brain formation

    • Principal Investigator
      Naoyuki Inagaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      Nara Institute of Science and Technology
  •  モデル脊椎動物ゼブラフィッシュを用いたリンパ管ネットワーク形成機構の解析Principal Investigator

    • Principal Investigator
      浦崎 明宏
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Developmental biology
    • Research Institution
      National Institute of Genetics
  •  脈管形成におけるmekk3bの役割の解明Principal Investigator

    • Principal Investigator
      浦崎 明宏
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Molecular biology
    • Research Institution
      National Institute of Genetics

All 2023 2022 2021 2020 2016 2015 2014 2009 Other

All Journal Article Presentation

  • [Journal Article] Computational and Experimental Analyses for Pathogenicity Prediction of ACVRL1 Missense Variants in Hereditary Hemorrhagic Telangiectasia2023

    • Author(s)
      Iwasa Toru、Urasaki Akihiro、Kakihana Yuki、Nagata-Akaho Nami、Harada Yukihiro、Takeda Soichi、Kawamura Teruhisa、Shiraishi Isao、Kurosaki Kenichi、Morisaki Hiroko、Yamada Osamu、Nakagawa Osamu
    • Journal Title

      Journal of Clinical Medicine

      Volume: 12 Issue: 15 Pages: 5002-5002

    • DOI

      10.3390/jcm12155002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15361, KAKENHI-PROJECT-22K06803, KAKENHI-PROJECT-19K08535, KAKENHI-PROJECT-21H02890
  • [Journal Article] Tmem100-BAC-EGFP mice to selectively mark and purify embryonic endothelial cells of large caliber arteries in mid-gestational vascular formation2021

    • Author(s)
      Yumi Kinugasa-Katayama, Yusuke Watanabe, Takashi Hisamitsu, Yuichiro Arima, Norika M Liu, Ayaka Tomimatsu, Yukihiro Harada, Yuji Arai, Akihiro Urasaki, Teruhisa Kawamura, Yoshihiko Saito, Osamu Nakagawa
    • Journal Title

      genesis

      Volume: 59 Issue: 4

    • DOI

      10.1002/dvg.23416

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07280, KAKENHI-PROJECT-18H02787, KAKENHI-PROJECT-19H03398, KAKENHI-PROJECT-21H02890
  • [Journal Article] ETS‐dependent enhancers for endothelial‐specific expression of serum/glucocorticoid‐regulated kinase 1 during mouse embryo development2021

    • Author(s)
      Harada Yukihiro, Tanaka Toru, Arai Yuji, Isomoto Yoshie, Nakano Atsushi, Nakao Shu, Urasaki Akihiro, Watanabe Yusuke, Kawamura Teruhisa, Nakagawa Osamu
    • Journal Title

      Genes to Cells

      Volume: 26 Issue: 8 Pages: 611-626

    • DOI

      10.1111/gtc.12874

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07280, KAKENHI-PROJECT-19H01140, KAKENHI-PROJECT-18H02787, KAKENHI-PROJECT-21K06790, KAKENHI-PROJECT-21K20751, KAKENHI-PROJECT-19H03398, KAKENHI-PROJECT-21H02890
  • [Journal Article] Identification of a shootin1 isoform expressed in peripheral tissues2016

    • Author(s)
      Yasuna Higashiguchi, Kazuhiro Katsuta, Takunori Minegishi, Shigenobu Yonemura, Akihiro Urasaki, Naoyuki Inagaki
    • Journal Title

      Cell Tissue Res.

      Volume: 366 Issue: 1 Pages: 75-87

    • DOI

      10.1007/s00441-016-2415-9

    • NAID

      120005818453

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26290007, KAKENHI-PROJECT-26840081
  • [Journal Article] Sox7 controls arterial specification in conjunction with hey2 and efnb2 function2015

    • Author(s)
      Hermkens DM, van Impel A, Urasaki A, Bussmann J, Duckers HJ, Schulte-Merker S
    • Journal Title

      Development

      Volume: 142 Pages: 1695-1704

    • DOI

      10.1242/dev.117275

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26840081
  • [Journal Article] ラージゲルプロテオミクスを基盤とした神経細胞の軸索形成とガイダンスの解析2014

    • Author(s)
      馬場健太郎、浦崎明宏、稲垣直之
    • Journal Title

      生物物理化学 電気泳動

      Volume: 第58巻 第2号 Pages: 49-52

    • NAID

      130004704685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290007
  • [Journal Article] Large gel proteomics-based analyses of the mechanisms for neuronal axon formation and guidance2014

    • Author(s)
      馬場健太郎、浦崎明宏、稲垣直之
    • Journal Title

      SEIBUTSU BUTSURI KAGAKU

      Volume: 58 Issue: 2 Pages: 49-52

    • DOI

      10.2198/sbk.58.49

    • NAID

      130004704685

    • ISSN
      0031-9082, 1349-9785
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-26840081
  • [Journal Article] Analysis of genes and genome by the To12-mediated gene and enhancer trap methods2009

    • Author(s)
      浦崎明宏
    • Journal Title

      Methods Mol Biol. 546

      Pages: 85-102

    • Data Source
      KAKENHI-PROJECT-21870041
  • [Journal Article] メダカトランスポゾンTo12が開く新しいゼブラフィッシュ研究2009

    • Author(s)
      浦崎明宏
    • Journal Title

      細胞工学 28

      Pages: 586-591

    • Data Source
      KAKENHI-PROJECT-21870041
  • [Presentation] Physiological importance of ALK1 signaling for organotypic vascular formation2022

    • Author(s)
      Akihiro URASAKI, Yuki KAKIHANA, Nami NAGATA-AKAHO, Yukihiro HARADA, Osamu NAKAGAWA
    • Organizer
      第6回日本循環器学会基礎研究フォーラム
    • Data Source
      KAKENHI-PROJECT-22K06803
  • [Presentation] Vascular connection between newly formed intestinal and pre-existing circulatory systems during embryonic development2022

    • Author(s)
      Akihiro URASAKI, Osamu NAKAGAWA
    • Organizer
      第30回日本血管生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02890
  • [Presentation] Vascular connection between newly formed intestinal and pre-existing circulatory systems during embryonic development2022

    • Author(s)
      Akihiro URASAKI, Osamu NAKAGAWA
    • Organizer
      第30回日本血管生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K06803
  • [Presentation] Physiological importance of ALK1 signaling for organotypic vascular formation2022

    • Author(s)
      Akihiro URASAKI, Yuki KAKIHANA, Nami NAGATA-AKAHO, Yukihiro HARADA, Osamu NAKAGAWA
    • Organizer
      第6回日本循環器学会基礎研究フォーラム
    • Data Source
      KAKENHI-PROJECT-21H02890
  • [Presentation] Physiological significance of ALK1 signaling in zebrafish organotypic vascular formation2021

    • Author(s)
      Akihiro Urasaki, Nami Akaho Nagata, Yuki Kakihana, Yukihiro Harada, Osamu Nakagawa
    • Organizer
      BCVR 第5回日本循環器学会基礎研究フォーラム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07280
  • [Presentation] Physiological significance of ALK1 signaling in zebrafish organotypic vascular formation2021

    • Author(s)
      Akihiro URASAKI, Nami NAGATA-AKAHO, Yuki KAKIHANA, Yukihiro HARADA, Osamu NAKAGAWA
    • Organizer
      第5回日本循環器学会基礎研究フォーラム
    • Data Source
      KAKENHI-PROJECT-21H02890
  • [Presentation] Physiological significance of ALK1 signaling in zebrafish organotypic vascular formation2021

    • Author(s)
      Akihiro URASAKI, Nami Akaho NAGATA, Yuki KAKIHANA, Yukihiro HARADA, Osamu NAKAGAWA
    • Organizer
      日本循環器学会基礎研究フォーラム
    • Data Source
      KAKENHI-PROJECT-18H02787
  • [Presentation] 臓器特異的血管形成におけるALK1シグナルの生理学的重要性2020

    • Author(s)
      浦崎明宏、中川修
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K07280
  • [Presentation] The role of singar during neuronal circuit development2016

    • Author(s)
      Takuro Kono,Hitomi Nakazawa,Colleen F. Manning,James S. Trimmer,Kenji Kohno,Akihiro Urasaki,Naoyuki Inagaki
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26290007
  • [Presentation] 神経回路形成におけるSingarの役割の解析2016

    • Author(s)
      高野 拓郎、中澤 瞳、Colleen F. Manning、James S. Trimmer、河野 憲二、浦崎明宏、稲垣 直之
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26840081
  • [Presentation] In vivo function of singar which regulates polarity of cultured hippocampal neurons2015

    • Author(s)
      Takuro, Kono., Hitomi, Nakazawa., Colleen, F Manning., James, S Trimmer., Kenji, Kono., Akihiro, Urasaki., Naoyuki, Inagaki.
    • Organizer
      第38回日本神経科学会大会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26290007
  • [Presentation] To12を用いたゼブラフィッシュ遺伝子の網羅的破壊2009

    • Author(s)
      浦崎明宏
    • Organizer
      日本遺伝学会第81回大会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-21870041
  • [Presentation] The gene trap approach reveals involvement of mekk3b in the functionsl blood vessel formation2009

    • Author(s)
      浦崎明宏
    • Organizer
      6th European Zebrafish Genetics and Development Meetins
    • Place of Presentation
      Rome
    • Data Source
      KAKENHI-PROJECT-21870041
  • [Presentation] ゼブラフィッシュを用いた脳形成におけるShootin1の役割の解析

    • Author(s)
      浦崎明宏、渡瀬恵美子、松井貴輝、川上浩一、別所康全、稲垣直之
    • Organizer
      第66回日本細胞生物学会大会
    • Place of Presentation
      奈良県新公会堂(奈良県奈良市)
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-26290007
  • [Presentation] Role of shootin1 during embryonic development in zebrafish

    • Author(s)
      A. Urasaki, T. Matsui, K. Kawakami, Y. Bessho, N. Inagaki
    • Organizer
      The 2014 ASCB meeting
    • Place of Presentation
      Philadelphia (USA)
    • Year and Date
      2014-12-06 – 2014-12-10
    • Data Source
      KAKENHI-PROJECT-26840081
  • [Presentation] 生体内における神経極性安定化因子Singarの役割の解析

    • Author(s)
      高野 拓郎,中澤 瞳,Colleen F Manning,James S Trimmer,河野 憲二,浦崎 明宏,稲垣 直之
    • Organizer
      第37回日本神経科学学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-26290007
  • [Presentation] ゼブラフィッシュを用いた脳形成におけるshootin1の役割

    • Author(s)
      浦崎明宏、渡瀬恵美子、松井貴輝、川上浩一、別所康全、稲垣直之
    • Organizer
      第66回日本細胞生物学会大会
    • Place of Presentation
      奈良県新公会堂(奈良県奈良市)
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-26840081
  • [Presentation] Role of shootin1 during embryonic development in zebrafish

    • Author(s)
      A.Urasaki, T.Matsui, K.Kawakami, Y.Bessho, N.Inagaki
    • Organizer
      2014 American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Pennsylvania Convention Center (Philadelphia,USA)
    • Year and Date
      2014-12-06 – 2014-12-10
    • Data Source
      KAKENHI-PROJECT-26290007
  • 1.  NAKAGWA Osamu (40283593)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 10 results
  • 2.  Watanabe Yusuke (20562333)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 3.  橋本 大輝 (40911342)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  原田 恭弘 (70911402)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 7 results
  • 5.  LAMRI LYNDA (90883984)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  垣花 優希 (40910534)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 7.  劉 孟佳 (50826922)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 8.  Iwasa Toru (80712843)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  白石 公 (80295659)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  瀬谷 大貴 (30806021)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  田中 亨 (50806065)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  能丸 寛子 (30885538)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  川村 晃久 (90393199)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  Naoyuki Inagaki (20223216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 15.  黒嵜 健一 (40561460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  石川 泰輔 (60708692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  田村 昌子 (30849261)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  西谷 友重 (50393244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小柴 和子 (30467005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  白井 学 (70294121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  高橋 篤 (50392014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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