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nanbu akiko  南部 晶子

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NAMBU AKIKO  南部 晶子

NANBU Akiko  南部 晶子

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Researcher Number 40572087
Other IDs
Affiliation (Current) 2025: 熊本大学, 大学院生命科学研究部(医), 客員助教
Affiliation (based on the past Project Information) *help 2019 – 2023: 熊本大学, 大学院生命科学研究部(医), 特別研究員
2018: 熊本大学, その他の研究科, 研究員
2018: 熊本大学, 大学院生命科学研究部(医), 研究員
2017: 熊本大学, 大学院生命科学研究部(医), 特別研究員(RPD)
2015: 熊本大学, その他の研究科, その他 … More
2015: 熊本大学, その他の研究科, 特別研究員
2014: 熊本大学, 生命科学研究科, 産学官連携研究員
2013: 熊本大学, 大学院生命科学研究部, 研究員
2012: 熊本大学, 生命科学研究部, 研究員
2011: 熊本大学, 大学院・生命科学研究部, 産学連携研究員
2011: 熊本大学, 生命科学研究部, 産学官連携研究員
2010: 熊本大学, 大学院・生命科学研究部, 産学連携博士研究員 Less
Review Section/Research Field
Principal Investigator
Tumor diagnostics / Tumor diagnosis / Tumor biology
Except Principal Investigator
Basic Section 56010:Neurosurgery-related
Keywords
Principal Investigator
がん幹細胞 / 脳腫瘍 / プロテオミクス / 分化 / プロテオーム / 糖鎖タンパク質 / 糖鎖 / グライコプロテオミクス / 分化ニッチ / 分化誘導 … More / 細胞外マトリックス / 腫瘍マーカー / スーパーエンハンサー / 脳腫瘍幹細胞 / エンハンサー / インテグリン / 白血病 / インターラクトーム / ニッチ / 癌幹細胞 / 膜タンパク質 / コンドロイチン硫酸 / グリオーマ幹細胞 / グライコミクス / グリオーマ / 微小環境 / プロテオグリカン / 細胞接着因子 / 融合プロテオミクス / DNAマイクロアレイ / 接着分子 / プロテオミクス解析 … More
Except Principal Investigator
神経線維腫症 / interactome / proteomics / NF2 / NF1 / neurofibromatosis Less
  • Research Projects

    (6 results)
  • Research Products

    (29 results)
  • Co-Researchers

    (17 People)
  •  Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of therapeutic strategies

    • Principal Investigator
      荒木 令江
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Kumamoto University
  •  Elucidation of the regulatory mechanisms of integrin expression by super-enhancer analysisPrincipal Investigator

    • Principal Investigator
      NAMBU AKIKO
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
    • Research Field
      Tumor diagnostics
    • Research Institution
      Kumamoto University
  •  Identification and functional analysis of glycoprotein factors involved in niche regulation of glioma initiating cellPrincipal Investigator

    • Principal Investigator
      NAMBU AKIKO
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Kumamoto University
  •  Elucidation of regulatory mechanisms related to differentiation niche of glioma stem-like cells by integrated glycoproteomicsPrincipal Investigator

    • Principal Investigator
      Nambu Akiko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Kumamoto University
  •  Identification of regulatory molecules related to the differentiation of glioma stem-like cells by an integrated protoemics.Principal Investigator

    • Principal Investigator
      NAMBU AKIKO
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor diagnosis
    • Research Institution
      Kumamoto University
  •  Establishment of Glioma stem-like cells(GSC) from glioma patient tumors and analysis of the novel molecular markers of GSC by an integrated proteomics.Principal Investigator

    • Principal Investigator
      NANBU Akiko
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor diagnosis
    • Research Institution
      Kumamoto University

All 2023 2022 2021 2020 2019 2015 2014 2013 2011

All Journal Article Presentation Book

  • [Book] 生物物理化学「特集:最新の電気泳動技術」2014

    • Author(s)
      荒木 令江, 南部(新堀) 晶子, 西村 宗徳, 緑川 宇一, 小林 大樹
    • Total Pages
      108
    • Publisher
      日本電気泳動学会
    • Data Source
      KAKENHI-PROJECT-26640083
  • [Book] 「神経線維腫症2型」母斑と母斑症皮膚科臨床アセット152013

    • Author(s)
      荒木令江, 南部晶子, 小林大樹
    • Data Source
      KAKENHI-PROJECT-24701007
  • [Book] 神経線維腫症2型2013

    • Author(s)
      荒木令江, 南部晶子, 小林大樹
    • Total Pages
      384
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-24701007
  • [Journal Article] Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells2023

    • Author(s)
      Koh CP., Bahirvani AG., Wang CQ., Yokomizo T., Ng CEL., Du L., Tergaonkar V., Voon DC., Kitamura H., Hosoi H., Sonoki T., Michelle MMH., Tan LJ., Niibori-Nambu A., Zhang Y., Perkins AS., Hossain Z., Tenen DG., Ito Y., Venkatesh B., Osato M.
    • Journal Title

      Gene

      Volume: 851 Pages: 147049-147049

    • DOI

      10.1016/j.gene.2022.147049

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-21K16248, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18KK0440, KAKENHI-PROJECT-23K24165
  • [Journal Article] Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.2022

    • Author(s)
      Bae KH, Lai F, Mong J, Niibori-Nambu A, Chan KH, Her Z, Osato M, Tan MH, Chen Q, Kurisawa M.
    • Journal Title

      J Nanobiotechnology

      Volume: 20 Issue: 1 Pages: 481-481

    • DOI

      10.1186/s12951-022-01683-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18KK0440, KAKENHI-PROJECT-23K24165
  • [Journal Article] Super-silencers regulated by chromatin interactions control apoptotic genens.2022

    • Author(s)
      Ying Zhang, Kaijing Chen, Yichao Cai, Akiko Nambu, Yi Z See, Chaoyu Fu, Anandhkumar Raju, Manikandan Lakshmanan, Motomi Osato, Vinay Tergaonkar, Melissa J Fullwood.
    • Journal Title

      BioRixv

      Volume: 1 Pages: 476559-476559

    • DOI

      10.1101/2022.01.17.476559

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0440
  • [Journal Article] Targeting alpha2,3-sialylated glycan in glioma stem-like cells by Maackia amurensis lectin-II: A promising strategy for glioma treatment2022

    • Author(s)
      1.Siyaporn Putthisen, Atit Slisirvanit, Orasa Panawan, Akiko Niibori-Nambu, Yuki Nishiyama-Ikeda, Prasersri Ma-In, Sukanya Laung, Kunimasa Ohta, Kanha Muisuk, Sopit Eongkham, Norie Araki
    • Journal Title

      Experimental Cell Research

      Volume: 410(1) Issue: 1 Pages: 112949-112949

    • DOI

      10.1016/j.yexcr.2021.112949

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07199, KAKENHI-PROJECT-19H03772
  • [Journal Article] RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner2021

    • Author(s)
      Abdallah Mohamed Gaber、Niibori-Nambu Akiko、Morii Mariko、Yokomizo Takako、Yokomizo Tomomasa, at al.
    • Journal Title

      Leukemia

      Volume: 35 Issue: 10 Pages: 2983-2988

    • DOI

      10.1038/s41375-021-01268-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02952, KAKENHI-PROJECT-19J40166, KAKENHI-PROJECT-17K07199, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-21K19512, KAKENHI-PROJECT-18KK0440, KAKENHI-PROJECT-23K21285
  • [Journal Article] Trib1 promotes the development of acute myeloid leukemia in a Ts1Cje mouse model of Down syndrome2021

    • Author(s)
      Yoshino Seiko、Tanaka Miwa、Sunami Yoshitaka、Takahara Tomoko、Yamazaki Yukari、Homme Mizuki、Niibori-Nambu Akiko、Osato Motomi、Minami Takashi、Ishihara Keiichi、Nakamura Takuro
    • Journal Title

      Leukemia

      Volume: 36 Issue: 2 Pages: 558-561

    • DOI

      10.1038/s41375-021-01384-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-19K07702, KAKENHI-PROJECT-20K16318, KAKENHI-PROJECT-20K17389, KAKENHI-PUBLICLY-20H05521, KAKENHI-PROJECT-19H01035, KAKENHI-PROJECT-21H02917, KAKENHI-PROJECT-17K07199, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18KK0440
  • [Journal Article] Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines2021

    • Author(s)
      Hosoi Hiroki、Niibori-Nambu Akiko、Nah Giselle Sek Suan、Bahirvani Avinash Govind、Mok Michelle Meng Huang、Sanda Takaomi、Kumar Alan Prem、Tenen Daniel G.、Ito Yoshiaki、Sonoki Takashi、Osato Motomi
    • Journal Title

      Gene

      Volume: 774 Pages: 145421-145421

    • DOI

      10.1016/j.gene.2021.145421

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07199, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K08821, KAKENHI-PROJECT-18KK0440, KAKENHI-PROJECT-19K17839
  • [Journal Article] A two-pronged anti-leukemic agent based on a hyaluronic acid?green tea catechin conjugate for inducing targeted cell death and terminal differentiation2020

    • Author(s)
      Liang Kun、Bae Ki Hyun、Nambu Akiko、Dutta Bibek、Chung Joo Eun、Osato Motomi、Kurisawa Motoichi
    • Journal Title

      Biomaterials Science

      Volume: 8 Issue: 1 Pages: 497-505

    • DOI

      10.1039/c9bm01146c

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18KK0440
  • [Journal Article] Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrinαV2013

    • Author(s)
      Akiko Niibori- Nambu, Midorikawa U, Mizuguchi S, Hide T, Nagai M, Komohara Y, Nagayama M, Hirayama M, Kobayashi D, Tsubota N, Takezaki T, Makino K, Nakamura H, Takeya M, Kuratsu K, Araki N
    • Journal Title

      PLoS ONE

      Volume: 8(5)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24701007
  • [Journal Article] Epiplakin modifies the motility of the HeLa cells and accumulates at the outer surfaces of 3-D cell clusters2013

    • Author(s)
      Shimada H, Nambu- Niibori A , Wilson-Morifuji M, Mizuguchi S, Araki N, Sumiyoshi H, Sato M, Mezaki Y, Senoo H, Ishikawa K, Hatano Y, Okamoto O, Fujiwara S
    • Journal Title

      J Deramatol

      Volume: 40(4) Pages: 249-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24701007
  • [Journal Article] Integrated proteomics identified novel activation of dynein IC2-GR-COX-1 signaling in NF1 disease model cells.2013

    • Author(s)
      Hirayama M, Kobayashi D, Mizuguchi S, Morikawa T, Nagayama M, Midorikawa U, Wilson MM, Nambu AN, Yoshizawa AC, Kawano S, Araki N.
    • Journal Title

      Molecular & Cellular Proteomics

      Volume: 28 Issue: 5 Pages: 1377-94

    • DOI

      10.1074/mcp.m112.024802

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23701060, KAKENHI-PROJECT-24700981, KAKENHI-PROJECT-24701007, KAKENHI-PROJECT-25293312, KAKENHI-PROJECT-25640068
  • [Journal Article] Glioma Initiating Cells Form a Differentiation Niche Via the Induction of Extracellular Matrices and Integrin aV2013

    • Author(s)
      Akiko Niibori-Nambu, Uichi Midorikawa, Souhei Mizuguchi, Takuichiro Hide, Minako Nagai,Yoshihiro Komohara, Megumi Nagayama, Mio Hirayama, Daiki Kobayashi, Nobuyuki Tsubota,Tatsuya Takezaki, Keishi Makino, Hideo Nakamura, Motohiro Takeya, Junichi Kuratsu, Norie Araki
    • Journal Title

      PLoS ONE

      Volume: 8(5) Issue: 5 Pages: e59558-e59558

    • DOI

      10.1371/journal.pone.0059558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23701060, KAKENHI-PROJECT-24700981, KAKENHI-PROJECT-24701007, KAKENHI-PUBLICLY-25130710, KAKENHI-PROJECT-25293312, KAKENHI-PROJECT-25462268, KAKENHI-PROJECT-25640068
  • [Journal Article] Epiplakin modifies the motility of the HeLa cells and accumulates at the outer surfaces of 3-D cell clusters.2013

    • Author(s)
      Shimada H, Nambu-Niibori A, Wilson-Morifuji M, Mizuguchi S, Araki N, Sumiyoshi H, Sato M, Mezaki Y, Senoo H, Ishikawa K, Hatano Y, Okamoto O, Fujiwara S
    • Journal Title

      J Dermatol

      Volume: 40 Issue: 4 Pages: 249-58

    • DOI

      10.1111/1346-8138.12076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591598, KAKENHI-PROJECT-23701060, KAKENHI-PROJECT-23791281, KAKENHI-PROJECT-24591918, KAKENHI-PROJECT-24701007, KAKENHI-PROJECT-25293312, KAKENHI-PROJECT-25640068, KAKENHI-PROJECT-25860959
  • [Journal Article] Integrated proteomics identified novel activation of dynein IC2-GR-COX-1 signaling in NF1 disease model cells2013

    • Author(s)
      Hirayama M, Kobayashi D, Mizuguchi S, Morikawa T, Nagayama M, Midorikawa U, Wilson MM, Nambu Akiko Niibori, Yoshizawa AC, Kawano S, Araki N
    • Journal Title

      Mol Cell Proteomics

      Volume: 12(5) Pages: 1377-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24701007
  • [Presentation] Molecular mimicry of niche-interacting status by ITGA9 overexpression underlines the extramedullary maintenance of leukemia stem cells in AML2021

    • Author(s)
      Akiko Niibori-Nambu
    • Organizer
      SICS 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0440
  • [Presentation] Molecular mimicry of niche-interacting status by ITGA9 overexpression underlines the extramedullary maintenance of leukemia stem cells in AML2021

    • Author(s)
      Akiko Niibori-Nambu
    • Organizer
      SICS 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07199
  • [Presentation] Targeting Integrin a9 by a Blocking Monoclonal Antibody in Acute Myeloid Leukemia2020

    • Author(s)
      Akiko Niibori-Nambu
    • Organizer
      Frontiers in Cancer Scneince
    • Data Source
      KAKENHI-PROJECT-18KK0440
  • [Presentation] Molecular Mimicry of Niche-Interacting Status by ITGA9 Overexpression Underlies the Extramedullary Maintenance of Leukemia Stem Cells in AML.2020

    • Author(s)
      Akiko Niibori-Nambu
    • Organizer
      Frontiers Cancer Science 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07199
  • [Presentation] Targeting Integrin a9 by a Blocking Monoclonal Antibody in Acute Myeloid Leukemia2019

    • Author(s)
      Akiko Niibori-Nambu
    • Organizer
      Frontiers in Cancer Science
    • Data Source
      KAKENHI-PROJECT-18KK0440
  • [Presentation] argeting Integrin a9 by a Blocking Monoclonal Antibody in Acute Myeloid Leukemia2019

    • Author(s)
      Akiko Niibori-Nambu
    • Organizer
      RUNX meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0440
  • [Presentation] 融合プロテオミクスを用いたグリオーマ幹細胞の分化・維持に関わる糖鎖タンパク質の同定2015

    • Author(s)
      南部 晶子
    • Organizer
      日本プロテオーム学会2015年会 (JHUPO第13回大会)
    • Place of Presentation
      くまもと森都心プラザ
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-26640083
  • [Presentation] Functional integrated proteomeics identified chondroitin sulfate proteoglycan- integrin signals as a regulator of the maintenance and differentiation of glioma initiating cells2015

    • Author(s)
      Akiko-Niibori Nambu
    • Organizer
      第74回日本癌学会学術総会 (2015)
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26640083
  • [Presentation] Integrated Proteomics Identified the Differentiation Niche Induced by Glioma Stem Cells2013

    • Author(s)
      A. Niibori Nambu
    • Organizer
      The Human Proteome Organization (HUPO) 12th Annual World Congress
    • Place of Presentation
      神奈川県横浜市国際展示場
    • Data Source
      KAKENHI-PROJECT-24701007
  • [Presentation] Integrated Proteomics Identified the Differentiation Niche Induced by Glioma Stem Cells2013

    • Author(s)
      A. Niibori Nambu, U Midorikawa, S. Mizuguchi, T. Hide, M. Nagai, Y. Komohara, M. Nagayama, M. Hirayama, D. Kobayashi, H. Nakamura, M. Takeya, J. Kuratsu, N. Araki
    • Organizer
      The Human Proteome Organization (HUPO) 12^<th> Annual World Congress
    • Place of Presentation
      Pacifico Yokohama, Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-24701007
  • [Presentation] 融合プロテオミクスによる幹細胞様グリオーマの分化制御機構の解析2011

    • Author(s)
      南部晶子, 緑川宇一, 水口惣平, 長山慈, 永井美奈子, 平野久, 荒木令江
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-22700905
  • [Presentation] 融合プロテオミクスによる幹細胞様グリオーマの分化制御機構の解析2011

    • Author(s)
      南部(新堀)晶子
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都府京都市、国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-22700905
  • 1.  ARAKI Norie (80253722)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 9 results
  • 2.  NAGAI Minako
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  MIZUGUCHI Souhei (50398103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  Narimatsu Hisashi (40129581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  武笠 晃丈 (90463869)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  福島 聡 (50398210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  藤田 美歌子 (00322256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  江良 択実 (00273706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  小林 大樹 (20448517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  北川 孝雄 (20614928)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MIDORIKAWA Uichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  大里 元美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 13.  横溝 智雅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  南 敬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  岡本 修
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  石川 一志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  藤原 作平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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