Takeda Hiroyuki 竹田浩之

… Alternative Names

TAKEDA Hiroyuki 竹田浩之

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Researcher Number	40609393
Other IDs
Affiliation (Current)	2025: 愛媛大学, プロテオサイエンスセンター, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 愛媛大学, プロテオサイエンスセンター, 准教授 2012 – 2015: 愛媛大学, プロテオサイエンスセンター, 助教
Review Section/Research Field	Principal Investigator Biomolecular chemistry / Basic Section 37010:Bio-related chemistry / Living organism molecular science Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 54040:Metabolism and endocrinology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 53020:Cardiology-related / Basic Section 49040:Parasitology-related / Dental engineering/Regenerative dentistry / Hygiene and public health / Endocrinology
Keywords	Principal Investigator 無細胞タンパク質合成 / 膜タンパク質 / 抗体 / GPCR / 抗原 / モノクローナル抗体 / プロテオリポソーム / イオンチャネル / プロテインアレイ / 無細胞膜タンパク質合成技術 … More / 脂質平面膜電位測定技術 / 複合体 / 脂質平面膜 / チャネル / 人工タンパク質デザイン / 細胞外ループ / 抗体医薬 / ヒスタミン受容体 / 膜貫通ドメイン / IgG / HRH1 / 人工デザイン抗原 / 受容体 / コムギ無細胞合成 / 脂質 / コムギ無細胞系 / 相互作用 / リポソーム / 味覚受容体 / DRD1 / AlphaScreen / スクリーニング … More Except Principal Investigator 自己炎症疾患 / プロテオミクス / ステロイドホルモン産生組織 / 質量分析 / AlphaScreen 法 / 卵巣 / 塩誘導キナーゼ / ステロイドホルモン / ヒトタンパク質アレイ / BioID / 近接依存性ビオチン化酵素 / インフラマソーム / コムギ胚芽無細胞タンパク質合成系 / Salt-Inducible Kinases / 標的プロテオミクス / ステロイドホルモン産生 / コムギ胚芽無細胞タンパク質合成 / タンパク質相互作用 / Salt-inducible kinases / 生殖 / がん / 無細胞タンパク合成 / 抗体 / GPCR / 疾患インタラクトーム / タンパク質アレイ / 疾患インララクトーム / ADC / 神経膠芽腫 / ミニチュア化 / 低分子抗体 / ミニチュア抗体 / VNAR抗体 / インテグリン / SVEP1 / 細胞外マトリックス / 心不全 / 24k-HUPA / 周期熱症候群 / ワクチン / インタラクトーム / タンパク質 / 赤血球 / マラリア原虫 / 女性生殖機能 / 質量分析法 / ユビキチン-プロテアソーム系 / 蛋白質分解 / SCF/beta-TRCP / 歯髄幹細胞 / 間葉系幹細胞 / beta-TRCP / Lipin1 / 脂質代謝 / タンパク質分解 / 無細胞系 / 発症トリガー / 家族性地中海熱 / 環境因子 / トルコ / 合成酵素 / イメージング / 副腎 / ステロイド合成酵素 / SIK / 塩誘導性キナーゼ / 質量分析イメージング / 排卵 / AlphaScreen Less

Elucidation of the roles of a new extracellular matrix protein SVEP1 in the pathogenesis of heart failure
- Principal Investigator
  
  坂田泰彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
神経膠芽腫治療に向けた革新的な抗体医療技術の開発
- Principal Investigator
  
  池田幸樹
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto University
  Kansai Medical University
Comprehensive disease-associated interactome and model mice elucidate diversity and periodicity of the autoinflammatory disease
- Principal Investigator
  
  増本純也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Ehime University
Development of novel therapeutic strategy for intractable cancers by the production of anti-GPCR antibodies using Cell-free protein synthesis technology
- Principal Investigator
  
  今井祐記
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Ehime University
Functional analysis of steroid hormone-producing tissues mediated by salt-inducible kinase-interactome
- Principal Investigator
  
  秦野修
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nara Medical University
Improvement of planar bilayer lipid membrane system for ion channels activity recordings using cell-free synthesized ion channel protein array.Principal Investigator
- Principal Investigator
  
  TAKEDA HIROYUKI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Ehime University
Functional analysis of salt-inducible kinase and steroid-producing tissues by targeted proteomics and mass spectrometry
- Principal Investigator
  
  秦野修
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nara Medical University
Comprehensive analyses of RBC-malaria parasite PPI interactome
- Principal Investigator
  
  Tsuboi Takafumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Ehime University
Comprehensive identification of responsible regulatory molecules that define the seizure periodicity and inflammatory diversity of autoinflammatory diseases
- Principal Investigator
  
  Masumoto Junya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Ehime University
Analysis of abnormal steroid hormone production by mass spectrometry imaging and targeted proteomics
- Principal Investigator
  
  Hatano Osamu
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nara Medical University
Comparative survey of endogenous and environmental factors that activate autoinflammatory disease responsible gene products in Turkey and Japan
- Principal Investigator
  
  MASUMOTO JUNYA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  Ehime University
Development of antibodies against extracellular region of receptors by using engineered membrane proteinsPrincipal Investigator
- Principal Investigator
  
  Takeda Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Ehime University
Modulation of lipid homeostasis in maintenance and directed differentiation of mesenchymal stem cells
- Principal Investigator
  
  Inuzuka Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Tohoku University
Development of assays and antibodies for functional analysis of taste receptors.Principal Investigator
- Principal Investigator
  
  Hiroyuki Takeda
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Ehime University
Assay development for analyzing high performance antibody selection based on cell-free synthesized GPCR proteoliposome.Principal Investigator
- Principal Investigator
  
  TAKEDA Hiroyuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Ehime University

[Book] 創薬研究のためのスクリーニング学実践テキスト　第3章-7. AlphaScreen による HTS2022
- Author(s)
  竹田浩之
- Total Pages
  5
- Publisher
  羊土社
- ISBN
  9784758122580
- Data Source
  KAKENHI-PROJECT-17K09887
[Book] 創薬研究のためのスクリーニング学実践テキスト　第3章-7. Alpha技術による HTS2022
- Author(s)
  竹田浩之
- Total Pages
  5
- Publisher
  羊土社
- ISBN
  9784758122580
- Data Source
  KAKENHI-PROJECT-20K08867
[Journal Article] CANE, a component of the NLRP3 inflammasome, promotes inflammasome activation2024
- Author(s)
  Kaneko Naoe、Kurata Mie、Yamamoto Toshihiro、Sakamoto Akimasa、Takada Yasutsugu、Kosako Hidetaka、Takeda Hiroyuki、Sawasaki Tatsuya、Masumoto Junya
- Journal Title
  
  Journal of Immunology
  
  Volume: 213 Issue: 1 Pages: 1-10
- DOI
  10.4049/jimmunol.2300175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19438, KAKENHI-PROJECT-23K27635, KAKENHI-PROJECT-23H05323
[Journal Article] Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen.2024
- Author(s)
  Takeda H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2766 Issue: 3 Pages: 107-128
- DOI
  10.3390/ijms25031419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08867, KAKENHI-PROJECT-21H02844, KAKENHI-PROJECT-21H03354
[Journal Article] Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen.2024
- Author(s)
  Takeda H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2766 Pages: 107-128
- DOI
  10.1007/978-1-0716-3682-4_12
- ISBN
  9781071636817, 9781071636824
- Data Source
  KAKENHI-PROJECT-23K07972
[Journal Article] Evaluation of Cell-Free Synthesized Human Channel Proteins for In Vitro Channel Research2022
- Author(s)
  Nishiguchi R, Tanaka T, Hayashida J, Nakagita T, Zhou W, Takeda H.
- Journal Title
  
  Membranes
  
  Volume: 13 Issue: 1 Pages: 48-48
- DOI
  10.3390/membranes13010048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08867, KAKENHI-PROJECT-20K05709
[Journal Article] A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins2021
- Author(s)
  Segawa Ryosuke、Takeda Hiroyuki、Yokoyama Takeshi、Ishida Momoha、Miyata Chihiro、Saito Taiji、Ishihara Ryosuke、Nakagita Tomoya、Sasano Yusuke、Kanoh Naoki、Iwabuchi Yoshiharu、Mizuguchi Mineyuki、Hiratsuka Masahiro、Hirasawa Noriyasu
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 194 Pages: 114819-114819
- DOI
  10.1016/j.bcp.2021.114819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07012, KAKENHI-PROJECT-21H00854, KAKENHI-PROJECT-17K09887, KAKENHI-PROJECT-20K05709, KAKENHI-PROJECT-20K08867
[Journal Article] A comprehensive interaction study provides a potential domain interaction network of human death domain superfamily proteins2021
- Author(s)
  Wei Zhou, Naoe Kaneko, Tomoya Nakagita, Hiroyuki Takeda, Junya Masumoto
- Journal Title
  
  Cell Death and Differentiation
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03719
[Journal Article] Plasmodium yoelii erythrocyte binding like protein interacts with basigin, an erythrocyte surface protein2021
- Author(s)
  Yuguchi T, Kanoi BN, Nagaoka H, Miura T, Ito D, Takeda H, Tsuboi T, Takashima E, Otsuki H
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: In press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03481
[Journal Article] Safety and efficacy of an anti-claudin-5 monoclonal antibody to increase blood-brain barrier permeability for drug delivery to the brain in a non-human primate2021
- Author(s)
  Tachibana K, Hashimoto Y, Shirakura K, Okada Y, Hirayama R, Iwashita Y, Nishino I, Ago Y, Takeda H, Kuniyasu H, Kondoh M
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 336 Pages: 105-111
- DOI
  10.1016/j.jconrel.2021.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K05709, KAKENHI-PROJECT-20K21659, KAKENHI-PROJECT-21H03354
[Journal Article] AGIA Tag System for Ultrastructural Protein Localization Analysis in Blood-Stage Plasmodium falciparum2021
- Author(s)
  Morita Masayuki、Kanoi Bernard N.、Shinzawa Naoaki、Kubota Rie、Takeda Hiroyuki、Sawasaki Tatsuya、Tsuboi Takafumi、Takashima Eizo
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 11 Pages: 777291-777291
- DOI
  10.3389/fcimb.2021.777291
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-20H02951, KAKENHI-PROJECT-20H03481, KAKENHI-PROJECT-21K06985, KAKENHI-PROJECT-21K19230
[Journal Article] CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP2021
- Author(s)
  Nishiyama Kanako、Maekawa Masashi、Nakagita Tomoya、Nakayama Jun、Kiyoi Takeshi、Chosei Mami、Murakami Akari、Kamei Yoshiaki、Takeda Hiroyuki、Takada Yasutsugu、Higashiyama Shigeki
- Journal Title
  
  Life Science Alliance
  
  Volume: 4 Issue: 9 Pages: e202101095-e202101095
- DOI
  10.26508/lsa.202101095
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18029, KAKENHI-PROJECT-19K18030, KAKENHI-PUBLICLY-21H00286, KAKENHI-PROJECT-21H02763, KAKENHI-PROJECT-20K05709
[Journal Article] A comprehensive interaction study provides a potential domain interaction network of human death domain superfamily proteins.2021
- Author(s)
  Wei Zhou, Naoe Kaneko, Tomoya Nakagita, Hiroyuki Takeda, Junya Masumoto
- Journal Title
  
  Cell Death Differ.
  
  Volume: 28 Issue: 11 Pages: 2991-3008
- DOI
  10.1038/s41418-021-00796-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04256, KAKENHI-PROJECT-20K05709
[Journal Article] Cell-Free Production of Proteoliposomes for Functional Analysis and Antibody Development Targeting Membrane Proteins2020
- Author(s)
  Zhou Wei、Takeda Hiroyuki
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 163 Issue: 163
- DOI
  10.3791/61871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05709
[Journal Article] Next-generation sequencing of the whole MEFV gene in Japanese patients with familial Mediterranean fever: a case-control association study2020
- Author(s)
  Tomohiro Koga, Shuntaro Sato, Hiroyuki Mishima, Kiyoshi Migita, Yushiro Endo, Masataka Umeda, Remi Sumiyoshi, Fumiaki Nonaka, Shoichi Fukui, Shin-Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Yukitaka Ueki, Junya Masumoto,et al.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 38 Suppl 127 Pages: 35-41
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03719
[Journal Article] KN3014, a piperidine-containing small compound, inhibits auto-secretion of IL-1β from PBMCs in a patient with Muckle?Wells syndrome2020
- Author(s)
  Kaneko Naoe、Kurata Mie、Yamamoto Toshihiro、Shigemura Tomonari、Agematsu Kazunaga、Yamazaki Takashi、Takeda Hiroyuki、Sawasaki Tatsuya、Koga Tomohiro、Kawakami Atsushi、Yachie Akihiro、Migita Kiyoshi、Yoshiura Koh-ichiro、Urano Takeshi、Masumoto Junya
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13562-13562
- DOI
  10.1038/s41598-020-70513-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07376, KAKENHI-PROJECT-18KK0245, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-20H03719, KAKENHI-PROJECT-20H01085
[Journal Article] Physiological functions of FBW7 in cancer and metabolism2018
- Author(s)
  Shimizu Kouhei、Nihira Naoe Taira、Inuzuka Hiroyuki、Wei Wenyi
- Journal Title
  
  Cellular Signalling
  
  Volume: 46 Pages: 15-22
- DOI
  10.1016/j.cellsig.2018.02.009
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19282, KAKENHI-PROJECT-18K19632, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-17H06531
[Journal Article] Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors2018
- Author(s)
  Clement Emilie、Inuzuka Hiroyuki、Nihira Naoe T.、Wei Wenyi、Toker Alex
- Journal Title
  
  Science Signaling
  
  Volume: 11 Issue: 521 Pages: 3810-3810
- DOI
  10.1126/scisignal.aao3810
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15811, KAKENHI-PROJECT-18K19632, KAKENHI-PROJECT-16H05529
[Journal Article] Production of Immunizing Antigen Proteoliposome Using Cell-Free Protein Synthesis System2018
- Author(s)
  Zhou Wei、Takeda Hiroyuki
- Journal Title
  
  Methods and Protocols, Methods in Molecular Biology
  
  Volume: 1868 Pages: 49-67
- DOI
  10.1007/978-1-4939-8802-0_7
- ISBN
  9781493988013, 9781493988020
- Data Source
  KAKENHI-PROJECT-16K01915
[Journal Article] SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation2018
- Author(s)
  Ci Yanpeng、Li Xiaoning、Chen Maorong、Zhong Jiateng、North Brian J.、Inuzuka Hiroyuki、He Xi、Li Yu、Guo Jianping、Dai Xiangpeng
- Journal Title
  
  Protein & Cell
  
  Volume: 9 Issue: 10 Pages: 879-889
- DOI
  10.1007/s13238-018-0510-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19632, KAKENHI-PROJECT-16H05529
[Journal Article] Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free system2018
- Author(s)
  Nakanishi Ayaka、Kaneko Naoe、Takeda Hiroyuki、Sawasaki Tatsuya、Morikawa Shinnosuke、Zhou Wei、Kurata Mie、Yamamoto Toshihiro、Akbar Sheikh Mohammad Fazle、Zako Tamotsu、Masumoto Junya
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 38 Issue: 1 Pages: 27-27
- DOI
  10.1186/s41232-018-0085-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17K19685, KAKENHI-PROJECT-18H00464, KAKENHI-PLANNED-16H06579
[Journal Article] SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis2018
- Author(s)
  Huang Li-Yu、Zhao Junjie、Chen Hao、Wan Lixin、Inuzuka Hiroyuki、Guo Jianping、Fu Xuhong、Zhai Yangyang、Lu Zhaoning、Wang Xuefei、Han Ze-Guang、Sun Yihong、Wei Wenyi
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 3569-3569
- DOI
  10.1038/s41467-018-06038-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19632, KAKENHI-PROJECT-16H05529
[Journal Article] Engineered membrane protein antigens successfully induce antibodies against extracellular regions of claudin-5.2018
- Author(s)
  Hashimoto Y, et al.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 8383-8383
- DOI
  10.1038/s41598-018-26560-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09887, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-16K01915, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-17J03990
[Journal Article] Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen.2018
- Author(s)
  Takeda-H
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1868 Pages: 93-112
- DOI
  10.1007/978-1-4939-8802-0_10
- ISBN
  9781493988013, 9781493988020
- Data Source
  KAKENHI-PROJECT-17K09887
[Journal Article] Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes2018
- Author(s)
  Suzuki Yasuyuki、Ogasawara Tomio、Tanaka Yuki、Takeda Hiroyuki、Sawasaki Tatsuya、Mogi Masaki、Liu Shuang、Maeyama Kazutaka
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 9 Pages: 38-38
- DOI
  10.3389/fphar.2018.00038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-15K19575, KAKENHI-PROJECT-18K08389, KAKENHI-PROJECT-16K01915
[Journal Article] Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models2017
- Author(s)
  Liu Shuang、Hasegawa Hitoshi、Takemasa Erika、Suzuki Yasuyuki、Oka Keizou、Kiyoi Takeshi、Takeda Hiroyuki、Ogasawara Tomio、Sawasaki Tatsuya、Yasukawa Masaki、Maeyama Kazutaka
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 5 Pages: 1584-1595
- DOI
  10.4049/jimmunol.1700192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01915, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-15H04858, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-15K19575
[Journal Article] Applications of reconstituted inflammasomes in a cell-free system to drug discovery and elucidation of the pathogenesis of autoinflammatory diseases.2017
- Author(s)
  Kaneko N, Iwasaki T, Ito Y, Takeda H, Sawasaki T, Morikawa S, Nakano N, Kurata M, Masumoto J.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 印刷中 Issue: 1 Pages: 9-9
- DOI
  10.1186/s41232-017-0040-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293232, KAKENHI-PROJECT-26305024, KAKENHI-PROJECT-17K19685, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17H00599
[Journal Article] G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells2017
- Author(s)
  Lijun Liu, Wojciech Michowski, Hiroyuki Inuzuka, Kouhei Shimizu, Naoe Taira Nihira, Joel M. Chick, Na Li, Yan Geng, Alice Y. Meng, Alban Ordureau, Aleksandra Kolodziejczyk, Keith L. Ligon, Roderick T. Bronson, Kornelia Polyak, J. Wade Harper, Steven P. Gygi, Wenyi Wei, Piotr Sicinski
- Journal Title
  
  Nature Cell Biology
  
  Volume: 19 Issue: 3 Pages: 177-188
- DOI
  10.1038/ncb3474
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15811, KAKENHI-PROJECT-16H05529
[Journal Article] Poly (I:C) and hyaluronic acid directly interact with NLRP3, resulting in the assembly of NLRP3 and ASC in a cell-free system.2017
- Author(s)
  Kaneko N, Ito Y, Iwasaki T, Takeda H, Sawasaki T, Migita K, Agematsu K, Koga T, Kawakami A, Yachie A, Yoshiura K, Morikawa S, Kurata M, Masumoto J.
- Journal Title
  
  European Journal of Inflammation
  
  Volume: 印刷中 Issue: 2 Pages: 85-97
- DOI
  10.1177/1721727x17711047
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293232, KAKENHI-PROJECT-26305024, KAKENHI-PROJECT-17K19685, KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17H00599
[Journal Article] The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.2017
- Author(s)
  Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.
- Journal Title
  
  Sci Signal. doi: 10.1126/scisignal.aah4117.
  
  Volume: 10 Issue: 460 Pages: 1-15
- DOI
  10.1126/scisignal.aah4117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253092, KAKENHI-PROJECT-16H05509, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16H05548, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18365, KAKENHI-PROJECT-15K18977, KAKENHI-PROJECT-15K15689, KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-26462829
[Journal Article] CP5 system, for simple and highly efficient protein purification with a C-terminal designed mini tag2017
- Author(s)
  Takeda Hiroyuki、Zhou Wei、Kido Kohki、Suno Ryoji、Iwasaki Takahiro、Kobayashi Takuya、Sawasaki Tatsuya
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: e0178246-e0178246
- DOI
  10.1371/journal.pone.0178246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01915, KAKENHI-PROJECT-17K09887, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-16H04729
[Journal Article] Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.2017
- Author(s)
  2.Nihira NT, Ogura K, Shimizu K, North BJ, Zhang J, Gao D, Inuzuka H, Wei W.
- Journal Title
  
  Science Signaling
  
  Volume: 10 Issue: 466
- DOI
  10.1126/scisignal.aai8026
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18977, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16K15811
[Journal Article] NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.2017
- Author(s)
  Fukushima H, Shimizu K, Watahiki A, Hoshikawa S, Kosho T, Oba D, Sakano S, Arakaki M
- Journal Title
  
  Mol Cell
  
  Volume: Nov 16;68(4) Issue: 4 Pages: 645-658
- DOI
  10.1016/j.molcel.2017.10.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17310, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-17H01606, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16H05548, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-17H04396, KAKENHI-PROJECT-16K15811, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-17H06531
[Journal Article] Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN couplex localization and promotes renal cancer progression2016
- Author(s)
  Nagashima, K., Fukushima, H., Shimizu, K., Hidaka, M., Hasumi, H., Ikebe, T., Fukumoto, S., Okabe, K., Inuzuka, H.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 6 Pages: 9947-9960
- DOI
  10.18632/oncotarget.14221
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25241012, KAKENHI-PROJECT-26253092, KAKENHI-PROJECT-16H05509, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16H05548, KAKENHI-PROJECT-16K11020, KAKENHI-PROJECT-15K15689, KAKENHI-PROJECT-26462829
[Journal Article] 無細胞技術を基盤とした抗GPCR モノクローナル抗体作製技術の開発2016
- Author(s)
  竹田浩之、澤崎達也
- Journal Title
  
  月刊バイオインダストリー
  
  Volume: 32 Pages: 56-62
- Data Source
  KAKENHI-PROJECT-26750365
[Journal Article] Claudin-1 Binder Enhances Epidermal Permeability in a Human Keratinocyte Model2015
- Author(s)
  Nakajima M, Nagase S, Iida M, Takeda S, Yamashita M, Watari A, Shirasago Y, Fukasawa M, Takeda H, Sawasaki T, Yagi K, Kondoh M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 354 Issue: 3 Pages: 440-447
- DOI
  10.1124/jpet.115.225391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26750365, KAKENHI-PROJECT-26860078
[Journal Article] Production of monoclonal antibodies against GPCR using cell-free synthesized GPCR antigen and biotinylated liposome-based interaction assay2015
- Author(s)
  Takeda H, Ogasawara T, Ozawa T, Muraguchi A, Jih PJ, Morishita R, Uchigashima M, Watanabe M, Fujimoto T, Iwasaki T, Endo Y, Sawasaki T
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 11333-11333
- DOI
  10.1038/srep11333
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06732, KAKENHI-PROJECT-15K09522, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-15H02500, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-25670463, KAKENHI-PROJECT-26640130, KAKENHI-PROJECT-26750365, KAKENHI-PROJECT-25290077, KAKENHI-PROJECT-26293237
[Journal Article] リポソーム添加型コムギ無細胞合成系による膜タンパク質合成とその利用2015
- Author(s)
  竹田浩之、野澤彰、澤崎達也
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 770-774
- NAID
  130007448253
- Data Source
  KAKENHI-PROJECT-26750365
[Journal Article] 無細胞タンパク質アレイを用いたプロテインキナーゼおよびユビキチンリガーゼの基質タンパク質探索技術2013
- Author(s)
  澤崎達也、竹田浩之、高橋宏隆、根本圭一郎
- Journal Title
  
  生化学
  
  Volume: 85 Pages: 438-446
- NAID
  10031184264
- Data Source
  KAKENHI-PROJECT-24710251
[Journal Article] 無細胞タンパク質アレイを用いたプロテインキナーゼおよびユビキチンリガーゼの基質タンパク質探索技術
- Author(s)
  澤崎達也, 竹田浩之, 高橋宏隆, 根本圭一郎
- Journal Title
  
  生化学
  
  Volume: 85 Pages: 438-446
- NAID
  10031184264
- Data Source
  KAKENHI-PROJECT-24710251
[Patent] マックルウェルズ症候群の治療用医薬組成物2020
- Inventor(s)
  増本純也、金子直恵、澤崎達也、竹田浩之
- Industrial Property Rights Holder
  愛媛大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03719
[Patent] マックル・ウェルズ症候群の治療用医薬組成物2019
- Inventor(s)
  増本純也、金子直恵、澤崎達也、竹田浩之
- Industrial Property Rights Holder
  増本純也、金子直恵、澤崎達也、竹田浩之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-238430
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] NLRP3インフラマソームの機能を調節する新規分子の同定2023
- Author(s)
  金子直恵、倉田美恵、山本敏弘、竹田浩之、澤崎達也、増本純也
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27635
[Presentation] Comprehensive interaction analysis using human protein array with 28,000 recombinant proteins2022
- Author(s)
  Hiroyuki Takeda
- Organizer
  The 20th Protein Island Matsuyama International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] Ultrastructual localization analysis of Plasmodium falciparum proteins using AGIA tag system2022
- Author(s)
  Morita M, Kanoi B, Shinzawa N, Takeda H, Sawasaki T, Tsuboi T, Takashima E
- Organizer
  The 20th Protein Island Matsuyama (PIM) International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03481
[Presentation] Ultrastructual localization analysis of Plasmodium falciparum merozoite proteins using AGIA tag-monoclonal antibody system2022
- Author(s)
  Morita M, Kanoi B, Shinzawa N, Kubota R, Takeda H, Sawasaki T, Tsuboi T, Takashima E
- Organizer
  International Congress of Parasitology (ICOPA) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03481
[Presentation] えひめから発信する創薬支援技術2022
- Author(s)
  竹田浩之
- Organizer
  生物化学的測定研究会第27回学術シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] ヒトプロテインアレイを用いた相互作用スクリーニング2022
- Author(s)
  竹田浩之
- Organizer
  第２回蛋白質科学会若手の会研究交流会
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] コムギ無細胞合成系を活用したイオンャネルKCNB1阻害抗体の開発2022
- Author(s)
  西口黎，中北智哉，今井祐記，竹田浩之
- Organizer
  第１回日本抗体学会設立記念学術大会
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] AGIA タグシステムによるマラリア原虫タンパク質の超微細局在解析2022
- Author(s)
  森田将之、カノイバーナード、新澤直明、窪田理恵、竹田浩之、澤崎達也、坪井敬文、高島英造
- Organizer
  第91回日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-20H03481
[Presentation] ヒトプロテインアレイとHTSを基盤とした創薬支援技術2022
- Author(s)
  竹田浩之
- Organizer
  第５回医薬品開発研究センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] コムギ無細胞合成系を用いたイオンチャネルKCNB1阻害抗体の開発2022
- Author(s)
  西口黎, 中北智哉, 今井祐記, 竹田浩之
- Organizer
  第15回無細胞生命科学研究会
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] えひめ・かずさプロテインアレイの整備とスクリーニング技術高度化2021
- Author(s)
  竹田浩之
- Organizer
  第15回無細胞生命科学研究会
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] A comprehensive interaction study provides a potential domain interaction network of human death domain superfamily proteins2021
- Author(s)
  Wei Zhou, Naoe Kaneko, Tomoya Nakagita, Hiroyuki Takeda, Junya Masumoto
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] 無細胞合成チャネルプロテインアレイの作製と活性評価2021
- Author(s)
  田中響久、中北智哉、西口黎、山川央、竹田浩之
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20K05709
[Presentation] A Comprehensive Analysis of Human Death Domain-fold Superfamily Interactome Using Recombinant Protein Array and AlphaScreen2020
- Author(s)
  Wei Zhou, Tomoya Nagagita, Naoe Kaneko, Hiroyuki Takeda, Junya Masumoto
- Organizer
  第20回日本蛋白質科学会年会 2020年 7月28日
- Data Source
  KAKENHI-PROJECT-20H03719
[Presentation] 無細胞合成タンパク質アレイと AlphaScreenを用いたヒト Death Domain-fold Superfamilyインタラクトームの網羅的研究2020
- Author(s)
  Wei Zhou, 竹田浩之, 中北智哉, 金子直恵, 増本純也.
- Organizer
  第93回日本生化学会大会 2020年 9月14日～16日
- Data Source
  KAKENHI-PROJECT-20H03719
[Presentation] インフラマソーム病に対する特異的低分子阻害薬の探索と分子病理診断への応用2020
- Author(s)
  増本純也, 金子直恵, 倉田美恵, 山本敏弘, 森川紳之祐, 竹田浩之, 澤崎達也, 重村倫成, 上松一永.
- Organizer
  第109回日本病理学会　2020年 4月16～18日
- Data Source
  KAKENHI-PROJECT-20H03719
[Presentation] 無細胞NLRP3インフラマソーム再構成系を用いた自己炎症疾患の分子標的薬の開発2019
- Author(s)
  金子直恵, 重村倫成, 上松一永, 倉田美恵, 竹田浩之, 澤崎達也, 森川紳之祐
- Organizer
  第42回日本分子生物学会年会(福岡)
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] Regulation of cell survival through post-translational modifications of MCL-1 in tumorigenesis2019
- Author(s)
  Hiroyuki Inuzuka, Kouhei Shimizu, Mitsuki Chiba, Satoshi Fukumoto, Wenyi Wei
- Organizer
  The Kick-off Symposium of Advanced Graduate Program for Future Medicine and Health Care
- Invited
- Data Source
  KAKENHI-PROJECT-16H05529
[Presentation] アミロイドとの直接相互作用によるNLRP3インフラマソーム形成の可能性2019
- Author(s)
  増本純也, 金子直恵, 中西文香, 竹田浩之, 澤崎達也, 座古保, 森川紳之祐
- Organizer
  第92回日本生化学会大会(横浜)
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] 無細胞インフラマソーム再構成系による創薬スクリーニング2019
- Author(s)
  金子直恵, 竹田浩之, 澤崎達也, 増本純也
- Organizer
  第92回日本生化学会大会(横浜)
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] NLRP3インフラマソームを活性化する未知分子の同定2019
- Author(s)
  増本純也，金子直恵，周薇，竹田浩之，澤崎達也，山本敏弘，森川紳之祐，倉田美恵
- Organizer
  第40回日本炎症・再生医学会(神戸)
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] 人工デザイン膜タンパク質抗原を用いたClaudin-5細胞領域結合抗体の開発2018
- Author(s)
  橋本洋祐、Wei Zhou、浜内孝太郎、白倉圭佑、土居健史、八木清仁、澤崎達也、岡田欣晃、近藤昌夫、竹田浩之
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] Accelerate drug discovery by cell-free technology2018
- Author(s)
  Hiroyuki Takeda
- Organizer
  Protein Island Matsuyama (PIM) 2018 International Symposium
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] ステロイドホルモンの質量分析イメージング解析とラット副腎皮質の再生2018
- Author(s)
  秦野修、磯崎勝弘、竹森洋、西村裕志、竹田浩之、岩崎哲史、大西健.
- Organizer
  第1回再生学異分野融合研究会　(岡崎市)
- Data Source
  KAKENHI-PROJECT-17K09887
[Presentation] Cell-free Synthesized Proteoliposome; a New Tool for Antibody Development against Integral Membrane Proteins.2018
- Author(s)
  Hiroyuki Takeda
- Organizer
  World Gene Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] 3.無細胞タンパク質複合体再構成系による自己炎症疾患の病態解明と特異的分子標的治療薬探索2018
- Author(s)
  増本純也, 金子直恵, 伊藤有紀, 山本敏弘, 倉田美恵, 中野直子, 森川紳之祐, 周薇, 竹田浩之, 澤崎達也
- Organizer
  第1回日本免疫不全・自己炎症学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] GPCRの細胞外領域認識抗体の効率的作製を目指した人工抗原デザイン2018
- Author(s)
  浜内孝太郎、澤崎達也、竹田浩之
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] 人工デザイン膜タンパク質抗原を用いたClaudin-5細胞外領域結合抗体の開発2018
- Author(s)
  橋本洋佑、Zhou Wei、浜内孝太郎、白倉圭佑、土井健史、八木清仁、澤崎達也、岡田欣晃、近藤昌夫、竹田浩之
- Organizer
  第13回無細胞生命科学研究会
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] CP5システム：C末ミニタグを用いた高効率タンパク質精製法2017
- Author(s)
  竹田浩之、城戸康希、Wei Zhou, 矢野智也、寿野良二、小林拓也、澤崎達也
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] CP5システム：C末端ミニタグとウサギモノクローナル抗体を用いた高効率タンパク質精製システム2017
- Author(s)
  竹田浩之、Wei Zhou、城戸康希、寿野良二、岩崎隆弘、小林拓也、澤崎達也
- Organizer
  ConBio2017（2017年度生命科学系学会合同年次大会）
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] Analysis of proteasome-dependent lipogenic pathway in hepatocytes2017
- Author(s)
  Seira Hoshikawa, Asami Watahiki, Hidefumi Fukushima, Satoshi Fukumoto, Hiroyuki Inuzuka
- Organizer
  Japan-NIH Joint Symposium
- Place of Presentation
  Sendai
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05529
[Presentation] GPCRの細胞外領域認識抗体の効率的作製を目指した人工抗原デザイン2017
- Author(s)
  浜内孝太郎、竹田浩之、澤崎達也
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16K01915
[Presentation] Production of monoclonal antibodies against GPCR using cell-free synthesized GPCR antigen and biotinylated liposome-based interaction assay2015
- Author(s)
  2) Takeda H, Ogasawara T, Ozawa T, Muraguchi A, Jih PJ, Morishita R, Uchigashima M, Watanabe M, Fujimoto T, Iwasaki T, Endo Y, Sawasaki T
- Organizer
  Protein Island Matsuyama international symposium
- Place of Presentation
  松山市男女共同参画推進センター（愛媛県・松山市）
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26750365
[Presentation] Production of monoclonal antibodies against GPCR using cell-free synthesized GPCR antigen and biotinylated liposome-based interaction assay.2015
- Author(s)
  Takeda H, Ogasawara T, Ozawa T, Muraguchi A, Jih PJ, Morishita R, Uchigashima M, Watanabe M, Fujimoto T, Iwasaki T, Endo Y, Sawasaki T.
- Organizer
  GPCR work shop
- Place of Presentation
  Kona, Big island Hawaii, Hi, USA
- Year and Date
  2015-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26750365
[Presentation] Synthesis of GPCR by Wheat Cell-free Protein Synthesis System, Which is Suitable for Biochemical Analysis and Monoclonal Antibody Production2014
- Author(s)
  Hiroyuki Takeda, Tomio Ogasawara, Tatsuhiko Ozawa, Atsushi Muraguchi, Yaeta Endo, Tatsuya Sawasaki
- Organizer
  Keystone Symposia : G Protein-Coupled Receptors - Structural Dynamics and Functional Implications
- Place of Presentation
  Snowbird, Utah, United States
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] Synthesis of GPCR by Wheat Cell-free Protein Synthesis System, Which is Suitable for Biochemical Analysis and Monoclonal Antibody Production2014
- Author(s)
  Hiroyuki Takeda, Tomio Ogasawara, Tatsuhiko Ozawa, Atsushi Muraguchi, Yaeta Endo, Tatsuya Sawasaki
- Organizer
  Keystone Symposia: G Protein-Coupled Receptors - Structural Dynamics and Functional Implications
- Place of Presentation
  Snowbird, Utah, United States
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] リポソーム添加コムギ無細胞系によるGPCRの発現と抗GPCRモノクローナル抗体作製2013
- Author(s)
  竹田浩之, 小笠原富夫, 小澤龍彦, 村口篤, 澤崎達也
- Organizer
  第8回無細胞生命科学研究会
- Place of Presentation
  新潟
- Year and Date
  2013-10-21
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] リポソーム添加コムギ無細胞系によるGPCRの発現と抗GPCRモノクローナル抗体作製2013
- Author(s)
  竹田浩之、小笠原富夫、小澤龍彦、村口篤、澤崎達也
- Organizer
  第８回　無細胞生命科学研究会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] Synthesis of GPCR by Wheat Cell-free Protein Synthesis System, Which is Suitable for Biochemical Analysis and Monoclonal Antibody Production2013
- Author(s)
  Hiroyuki Takeda, Tomio Ogasawara, Tatsuhiko Ozawa, Atsushi Muraguchi, Yaeta Endo, Tatsuya Sawasaki
- Organizer
  GPCR workshop 2013
- Place of Presentation
  Maui, Hawaii, United States
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] リポソーム添加コムギ無細胞タンパク質合成系を用いた膜タンパク質の汎用的合成法とそのアプリケーション2013
- Author(s)
  竹田浩之
- Organizer
  日本プロテオーム学会主催プロテオサイエンスセンター・JHUPOサテライトジョイントシンポジウム
- Place of Presentation
  松山
- Year and Date
  2013-06-07
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] ポソーム添加コムギ無細胞系によるGPCRの発現と抗GPCRモノクローナル抗体作製2012
- Author(s)
  竹田浩之, 小笠原富夫, 平賀清貴, 遠藤弥重太, 澤崎達也
- Organizer
  第7回無細胞生命科学研究会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] Membrane protein synthesis by wheat cell-free system with liposome2012
- Author(s)
  Hiroyuki Takeda, Tomio Ogasawara, Kenta Kohara, Kiyotaka Hiraga, Yukiko Washino, Takahiro Iwasaki, Yaeta Endo, Tatsuya Sawasaki
- Organizer
  Protein Island Matsuyama 2012
- Place of Presentation
  松山
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] Synthesis of GPCR by Wheat Cell-free Protein Synthesis System; Application for Functional Analysis and Monoclonal Antibody Production2012
- Author(s)
  Hiroyuki Takeda, Tomio Ogasawara, Mamoru Takahashi, Yaeta Endo, Tatsuya Sawasaki
- Organizer
  IBC 23rd Annual International Conference Antibody Engineering & Therapeutics
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] Synthesis of GPCR by Wheat Cell-free Protein Synthesis System; Application for Functional Analysis and Monoclonal Antibody Production2012
- Author(s)
  Hiroyuki Takeda, Tomio Ogasawara, Mamoru Takahashi, Yaeta Endo, Tatsuya Sawasaki
- Organizer
  The 4th Membrane Protein Technologies Meeting
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] リポソーム添加コムギ無細胞系によるGPCRの発現と抗GPCRモノクローナル抗体作製2012
- Author(s)
  竹田浩之、小笠原富夫、平賀清貴、遠藤弥重太、澤崎達也
- Organizer
  第７回無細胞生命科学研究会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] Cell-free Synthesized G-protein-coupled Receptor Proteoliposome is Efficient for Biochemical Analysis and Monoclonal Antibody Development
- Author(s)
  Hiroyuki Takeda, Tomio Ogasawara, Tatsuhiko Ozawa, Atsushi Muraguchi, Yaeta Endo, Tatsuya Sawasaki
- Organizer
  Discovery on Target 2014
- Place of Presentation
  米国ボストン
- Year and Date
  2014-10-08 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26750365
[Presentation] リポソーム添加コムギ無細胞タンパク質合成系を用いた膜タンパク質の汎用的合成法とそのアプリケーション
- Author(s)
  竹田浩之
- Organizer
  日本プロテオーム学会主催　プロテオサイエンスセンター・JHUPOサテライトジョイントシンポジウム
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-24710251
[Presentation] コムギ無細胞タンパク質合成系を基盤とした甘味受容体機能構造解析のための技術開発
- Author(s)
  栄谷紘一・竹田浩之・小澤龍彦・村口篤・澤崎達也
- Organizer
  GPCR研究会
- Place of Presentation
  日本科学未来館
- Year and Date
  2014-05-09 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-26750365

1. Hatano Osamu (40164850)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. MASUMOTO JUNYA (20334914)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
3. 竹森洋 (90273672)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 右田清志 (60264214)

# of Collaborated Projects: 3 results

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5. 川上純 (90325639)

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6. 大西健 (50152195)

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8. 吉浦孝一郎 (00304931)

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9. 古賀智裕 (90537284)

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# of Collaborated Products: 1 results
10. Inuzuka Hiroyuki (20335863)

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# of Collaborated Products: 7 results
11. Tsuboi Takafumi (00188616)

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# of Collaborated Products: 4 results
12. 三宅牧人 (80601400)

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13. 谷内江昭宏 (40210281)

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14. 上松一永 (60262721)

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15. 福本敏 (30264253)

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# of Collaborated Products: 3 results
16. 齋藤正寛 (40215562)

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17. 福島秀文 (70412624)

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18. 高島英造 (50366762)

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# of Collaborated Products: 4 results
19. 堀内浩幸 (80243608)

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26. 伊藤慎 (20796560)

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27. 池田幸樹 (10633026)

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28. 小澤龍彦 (10432105)

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29. 宮川拓也 (50596559)

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31. 小迫英尊 (10291171)

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32. 岸田大 (50467180)

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33. 山中聡士 (50853884)

# of Collaborated Projects: 1 results

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34. 浦野健 (70293701)

# of Collaborated Projects: 1 results

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35. 今井祐記 (10423873)

# of Collaborated Projects: 1 results

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36. YOKOYAMA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. Kaneko Naoe

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. SHIMIZU Kouhei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
39. AGO Yukio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. KURATA Mie

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# of Collaborated Products: 1 results
41. UCHIGASHIMA Motokazu

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# of Collaborated Products: 1 results
42. OGURA Kohei

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43. ARAKAKI Makiko

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44. 日高真純

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45. 伊藤有紀

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46. 近藤昌夫

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47. 村上朱里

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# of Collaborated Products: 1 results

Takeda Hiroyuki 竹田 浩之

TAKEDA Hiroyuki 竹田 浩之

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Improvement of planar bilayer lipid membrane system for ion channels activity recordings using cell-free synthesized ion channel protein array.Principal Investigator

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Development of antibodies against extracellular region of receptors by using engineered membrane proteinsPrincipal Investigator

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Development of assays and antibodies for functional analysis of taste receptors.Principal Investigator

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Assay development for analyzing high performance antibody selection based on cell-free synthesized GPCR proteoliposome.Principal Investigator

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Takeda Hiroyuki 竹田浩之

TAKEDA Hiroyuki 竹田浩之

[Book] 創薬研究のためのスクリーニング学実践テキスト　第3章-7. AlphaScreen による HTS2022

[Book] 創薬研究のためのスクリーニング学実践テキスト　第3章-7. Alpha技術による HTS2022