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Urano Takeshi  浦野 健

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URANO Takeshi  浦野 健

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Researcher Number 70293701
Other IDs
External Links
Affiliation (Current) 2025: 島根大学, 学術研究院医学・看護学系, 特任教授
Affiliation (based on the past Project Information) *help 2024 – 2025: 島根大学, 学術研究院医学・看護学系, 特任教授
2018 – 2024: 島根大学, 学術研究院医学・看護学系, 教授
2013 – 2017: 島根大学, 医学部, 教授
2007 – 2011: Shimane University, 医学部, 教授
2006: Nagoya University, Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 … More
2002 – 2006: Nagoya University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授
2001: 名古屋大学, 大学院・医学研究科, 助教授
1998 – 2000: 名古屋大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
General medical chemistry / Pathological medical chemistry / Biological Sciences / Basic Section 54020:Connective tissue disease and allergy-related / Laboratory medicine
Except Principal Investigator
Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 43020:Structural biochemistry-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / General medical chemistry / Digestive surgery … More / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 49060:Virology-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 55020:Digestive surgery-related / Basic Section 38060:Applied molecular and cellular biology-related / Collagenous pathology/Allergology / General medical chemistry / Structural biochemistry / Surgical dentistry / Biological Sciences Less
Keywords
Principal Investigator
Aurora / 細胞周期 / タンパク質分解 / 修飾特異的モノクローナル抗体 / ヒストンH3メチル化 / ヒストンH3リン酸化 / プロテインキナーゼ / イメージング技術 / 脱リン酸化酵素 / がん … More / リン酸化酵素 / 炎症性サイトカイン / バイオ医薬品 / IL-18 / モノクローナル抗体 / 分裂期キナーゼ / 染色体分離 / 染色体リモデリング複合体 / 分子標的 / 細胞分裂 / 染色体 / 中心体 / アンチセンスオリゴDNA / APC / 蛋白質分解 / 造腫瘍能 / Aurora2 / リン酸化 / 難治性炎症疾患 / 抗体治療 / 間質性肺炎 / 抗IL-18活性化断端抗体 / インターロイキン-18 / 活性型 IL-18 測定キット / 潰瘍性大腸炎 / クローン病 / 炎症性腸炎 / 機能阻害抗体 / インターロイキン-18(IL-18) / 臨床検査医学 / 測定キット / IL-1β / 炎症 / calcium / calmodulin / mitotic kinase / Cell cycle / 染色体パッセンジャータンパク質 / オーロラキナーゼ / カルシウム / カルモジュリン / 細胞分裂期キナーゼ / オーロラ / 細胞周期制御 / monoclonal antibodies / image analyzing system / molecular target / cancer / protein degradation / protein phosphatases / protein kinases / cell cycle / アルギニン依存性キナーゼ / ヒストンH3 / オカダ酸 / 動原体 / Aurora-B / non-receptor tyrosine kinase c-src / SH3 domain / EF-hand motif / EGF receptor substrate / Signal Transducer Reps / Small GTPase Ral / Small GTPase Ras / 癌原遺伝子産物c-src / SH3領域 / EF-handモチーフ / EGF受容体基質様領域 / シグナル伝達蛋白Reps / 低分子量G蛋白Ral / 低分子量G蛋白Ras / NCoA-3 / NAC-1 / メチル化 / がん関連転写制御因子 / 核内受容体コアクティベータ / メチル基 / アルギニン残基 / 翻訳後修飾 / ヒストン / WAF1 / p21 / スレオニンキナーゼ / セリン / 基質特異性 / ユビキチン化 / SIAH-1 / EB3 / リン酸化モノクローナル抗体 / p53 / FRET / 中心体局在配列 / GFP融合タンパク質 / タイムラプス観察 / カルモジュリン結合蛋白 / 神経特異的 / 低分子量G蛋白Rin … More
Except Principal Investigator
立体構造解析 / RNAスプライシング / 膵がん / neuron / ganglioside / ノックアウト / ニューロン / ガングリオシド / モノクローナル抗体 / IL-18 / 家族性地中海熱 / インフラマソーム / 成人発症スチル病 / 自己炎症 / 補体 / 炎症 / 神経変性 / degeneration / 糖転移酵素 / スフィンゴ糖脂質 / 変性 / 構造解析 / PTH1型受容体 / 副甲状腺癌 / PTH / Ca / 副甲状腺ホルモン / dengue vaccine / ワクチン / ヒアルロン酸ナノゲル / エンベロープ(E)タンパク質 / デングウイルス / デング熱 / ショウガ / インターロイキン18 / タンパク質アレイ / 疾患インララクトーム / 疾患インタラクトーム / ヒトタンパク質アレイ / 自己炎症疾患 / マクロファージ活性化症候群 / 免疫老化 / IL-18 阻害抗体 / 化学療法 / 活性化断端抗体 / インターロイキン-18 / 炎症性サイトカイン / パイロトーシス / 5-フルオロウラシル / 抗IL-18活性化断端抗体 / 炎症性細胞死(パイロトーシス) / 5ーフルオロウラシル(5-FU) / 機能阻害抗体 / インターロイキン-18(IL-18) / エクソンスキップ / エクソンスキップ療法 / 急性骨髄性白血病 / スプライシング / IL-IB / パイソン / 自然免疫 / 単球 / IL-1β / C5a / パイリン / Caspase-1 / 抗体療法 / Interleukin-18 / Pancreatic cancer / 5-フルオロウラシル(5-FU) / 阻害抗体 / 膵臓がん / インターロイキン18(IL-18) / MEFV遺伝子 / 全ゲノム解析 / 血清バイオマーカー / バイオマーカー / X線結晶構造解析 / クロマチン制御 / DNA塩基配列 / ソフトウェア / ヒストン / DNA / エピジェネティクス / ヌクレオソーム / 内科 / IL-1 / カスパーゼ1 / 自己炎症インフラマソーム カスパーゼ1 IL-1 / インフラソーム / IL-Iβ / バイオ医薬品開発 / がん表面抗原 / 治療法 / 早期診断 / inflammation / raft / nerve / glycolipid / knockout / セロトニン / アセチルコリン / 遺伝子発現 / GD3 / グリア / ラフト / 神経 / 糖脂質 / dorsal root ganglia / purkinje cell / cerebeilum / neuradegeneration / targeting / glysyltransferase / プロキンエ細胞 / 脊髄 / サブトラクション / 後根神経節 / プルキンエ細胞 / 小脳 / ターゲッティング / cloning / knock-out / carbohydrate / トランスフェクション / ジーンノックアウト / リモデリング / スィンゴ糖脂質 / トランスジェニック / クローニング / 糖鎖 / 胆道発癌 / ヘパティクス菌 / ビリス菌 / 胆汁耐性ヘリコバクター属菌 / 胆道発がん / 創薬 / 抗体 / RNAポリメラーゼ / インフルエンザ / Aurora / 分裂期キナーゼ / TRF1 / 卵抽出液 / アフリカツメガエル / M期 / S期 / ヘテロクロマチン / SAHF / がん抑制機構 / HMGA2 / ヒストンH1 / 細胞老化 / ALT / Pot1 / シグナル伝達 / 癌 / テロメレース / クロマチン / テロメア / 染色体 Less
  • Research Projects

    (36 results)
  • Research Products

    (151 results)
  • Co-Researchers

    (38 People)
  •  ショウガの持つIL-18活性化阻害の作用機序解明と医療応用に向けた基礎研究

    • Principal Investigator
      加美野 宏樹
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Shimane University
  •  マクロファージ活性化症候群の新しいマウスモデルの作製と治療応用に向けた研究

    • Principal Investigator
      杉浦 智子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Shimane University
  •  Comprehensive disease-associated interactome and model mice elucidate diversity and periodicity of the autoinflammatory disease

    • Principal Investigator
      増本 純也
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Ehime University
  •  スプライシングにおけるイントロン認識機構と病気発症メカニズムの解明

    • Principal Investigator
      尾林 栄治
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Shimane University
  •  Fundamental research on infection prevention using hyaluronic acid nanogel vaccine against dengue virus

    • Principal Investigator
      ヌグエ・トン ミャ・ミャッ
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Shimane University
  •  PTH1型受容体に対する阻害抗体を用いた難治性副甲状腺癌の制御

    • Principal Investigator
      野津 雅和
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Shimane University
  •  The Role of Immunosenescence in the Pathogenesis of Familial Mediterranean Fever

    • Principal Investigator
      Koga Tomohiro
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nagasaki University
  •  Effects of disease-associated mutations in splicing proteins on RNA splicing

    • Principal Investigator
      Obayashi Eiji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Shimane University
  •  Fundamental Research Toward Exon Skipping Therapy for Acute Myeloid Leukemia

    • Principal Investigator
      Sakashita Gyosuke
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Shimane University
  •  Basic research on antibody therapy against inflammatory cytokine IL-18 for refractory inflammatory diseasesPrincipal Investigator

    • Principal Investigator
      Urano Takeshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Shimane University
  •  Fundamental study for the treatment of pancreatic cancer by a combination of chemotherapy and IL-18 function-blocking antibody

    • Principal Investigator
      Tajima Yoshitsugu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Shimane University
  •  Development of novel pancreatic cancer treatment using IL-18 inhibitory antibody

    • Principal Investigator
      KAMINO Hiroki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Shimane University
  •  Revealing the mechanism of pyrin inflammasome activation and the development of its control methods

    • Principal Investigator
      Migita Kiyoshi
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Fukushima Medical University
  •  Development of biomarkers for "early diagnosis" and "realization of precision medicine" of familial Mediterranean fever

    • Principal Investigator
      Koga Tomohiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nagasaki University
  •  Elucidation of the role of internal DNA sequences in dynamic nucleosome regulation

    • Principal Investigator
      Kato Hiroaki
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38060:Applied molecular and cellular biology-related
    • Research Institution
      Shimane University
  •  Elucidation of the intron recognition mechanism by U2AF1

    • Principal Investigator
      Obayashi Eiji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Shimane University
  •  Development of refined detection system for mature and active IL-1b family proteinsPrincipal Investigator

    • Principal Investigator
      Takeshi Urano
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Shimane University
  •  Autoinflammatory biomarker for the new classification of rheumatic disease and identification of therapeutic target

    • Principal Investigator
      Migita Kiyoshi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Fukushima Medical University
  •  Two types of monoclonal antibodies generated by immunizing mice with MIA-PaCa-2 human pancreatic cancer cell line for diagnostic and therapeutic strategies for pancreatic cancer

    • Principal Investigator
      Tajima Yoshitsugu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Shimane University
  •  The mechanism analysis of influenza RNA polymerase

    • Principal Investigator
      Park Sam-Yong
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Yokohama City University
  •  Establishment of early diagnosis of enterohepatic Helicobacters infection for prophylaxis and treatment of biliary tract cancers

    • Principal Investigator
      Tajima Yoshitsugu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Shimane University
  •  Arginine methylation in histone codePrincipal Investigator

    • Principal Investigator
      URANO Takeshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Shimane University
  •  The elucidation of molecule morbidity of Aurora kinase in oral squamous cell carcinoma, and the application to the medical treatment strategy

    • Principal Investigator
      KONDO Seiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
      Shimane University
  •  The regulatory mechanism of sensor-type transcription factor during mitosisPrincipal Investigator

    • Principal Investigator
      URANO Takeshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Shimane University
      Nagoya University
  •  How Chromosomal Aberrations Are Induced by Telomere Dysfunction

    • Principal Investigator
      ISHIKAWA Fuyuki
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Mechanisms for the biosignal regulation with glycosphingolipids and their redundancy

    • Principal Investigator
      FURUKAWA Kouichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Nagoya University
  •  Molecular basis of Cancer-specific cell cyclePrincipal Investigator

    • Principal Investigator
      URANO Takeshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Nagoya University
  •  プロテインキナーゼAuroraによる染色体分配制御の分子基盤Principal Investigator

    • Principal Investigator
      浦野 健
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  プロテインキナーゼAuroraによる染色体均等分離の制御機構とがん治療への応用Principal Investigator

    • Principal Investigator
      浦野 健
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  細胞周期による中心体キナーゼAurora-Aの活性化の時間的・空間的イメージングPrincipal Investigator

    • Principal Investigator
      浦野 健
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoya University
  •  Analysis of in vivo function of glycosphingolipids with glycosylation mutant mice

    • Principal Investigator
      FURUKAWA Koichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Nagoya University
  •  G2/M期を制御するプロテインキナーゼAuroraの細胞内情報伝達機構Principal Investigator

    • Principal Investigator
      浦野 健
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Molecular mechanism of G2/M Progression by protein kinasesPrincipal Investigator

    • Principal Investigator
      URANO Takeshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoya University
  •  神経特異的カルモジュリン結合低分子量G蛋白Rinの新規シグナル伝達系の解析Principal Investigator

    • Principal Investigator
      浦野 健
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya University
  •  The regulation of growth and differentiation signales of nerve cells bar sphingoglycolipids.

    • Principal Investigator
      FURUKAWA Koichi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General medical chemistry
    • Research Institution
      Nagoya University
  •  Repsl, which may coordinate a wide variety of the cellular actionsPrincipal Investigator

    • Principal Investigator
      URANO Takeshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoya University

All 2025 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 2000

All Journal Article Presentation Book Patent

  • [Book] 細胞周期集中マスター 北川雅敏編、-レビュー編第1 章細胞周期を制御するリン酸化酵素-2006

    • Author(s)
      浦野 健
    • Publisher
      株式会社羊土社
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Book] 細胞周期集中マスター -第1章 細胞周期を制御するリン酸化酵素(レビュー編)-(北川雅敏編)2006

    • Author(s)
      浦野 健
    • Total Pages
      154
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Molecular and serological evidence of chikungunya virus among dengue suspected patients in Sri Lanka2025

    • Author(s)
      Ngwe Tun Mya Myat、Mutua Maurine Mumo、Inoue Shingo、Takamatsu Yuki、Kaneko Satoshi、Urano Takeshi、Muthugala Rohitha、Fernando Lakkumar、Hapugoda Menaka、Gunawardene YINS、Morita Kouichi
    • Journal Title

      Journal of Infection and Public Health

      Volume: 18 Issue: 5 Pages: 102709-102709

    • DOI

      10.1016/j.jiph.2025.102709

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K02288, KAKENHI-PROJECT-24K10246
  • [Journal Article] Prevalence of chikungunya virus infection in Sabah, Malaysia during 2017?20202025

    • Author(s)
      Ngwe Tun Mya Myat、John Jecelyn Leaslie、Nguyen Thanh Vu、Mutua Maurine Mumo、Manah Abdul Marsudi、Takamatsu Yuki、Urano Takeshi、Morita Kouichi、Ahmed Kamruddin
    • Journal Title

      Tropical Medicine and Health

      Volume: 53 Issue: 1 Pages: 55-55

    • DOI

      10.1186/s41182-025-00735-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K10246
  • [Journal Article] Comparison of clinical and virological features in pediatric and adult dengue cases at Insein General Hospital during Myanmar’s 2022 dengue season2025

    • Author(s)
      Lin Htin、Ngwe Tun Mya Myat、Zin Yin Mon Wint、Myint Khin Theingi、Khine Win Kay、Nwe Khine Mya、Thant Aye Aye、Shwe Thin Thin、Mar Win、Aye Khin Sandar、Aung Khaing Moe、Takamatsu Yuki、Aung Wah Wah、Kyaw Yi Yi、Urano Takeshi、Morita Kouichi、Thu Hlaing Myat
    • Journal Title

      Tropical Medicine and Health

      Volume: 53 Issue: 1 Pages: 1-10

    • DOI

      10.1186/s41182-025-00688-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K02288, KAKENHI-PROJECT-24K10246
  • [Journal Article] Molecular and Entomological Characterization of 2023 Dengue Outbreak in Dhading District, Central Nepal2024

    • Author(s)
      Rimal S、Shrestha S、Poudel AW、Shah Y、Bhandari G、Pandey K、Kharbuja A、Kapandji M、Gautam I、Bhujel R、Takamatsu Yi、Bhandari R、Klungthong C、Shrestha SK、Fernandez S、Malavige N、Pandey BD、Urano T、Morita K、NT Mya Myat、Dumre SP
    • Journal Title

      Viruses

      Volume: 16 Issue: 4 Pages: 594-594

    • DOI

      10.3390/v16040594

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K10246
  • [Journal Article] Monoclonal Antibodies Against Mature Interleukin-18 Ameliorate Colitis and Repair Goblet Cell Function2024

    • Author(s)
      Mu Jingxi、Maeda Keiko、Ohashi Ayako、Urano Takeshi、Nariai Yuko、Kamino Hiroki、Nakamura Masanao、Yamamura Takeshi、Sawada Tsunaki、Ishikawa Eri、Murate Kentaro、Yamamoto Kenta、Hirose Takashi、Furukawa Kazuhiro、Fujishiro Mitsuhiro、Kawashima Hiroki
    • Journal Title

      Digestive Diseases and Sciences

      Volume: - Issue: 7 Pages: 2573-2585

    • DOI

      10.1007/s10620-024-08453-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-21K15920
  • [Journal Article] Possible vertical transmission of Chikungunya virus infection detected in the cord blood samples from a birth cohort in Vietnam2024

    • Author(s)
      Ngwe Tun Mya Myat、Luvai Elizabeth Ajema Chebichi、Toizumi Michiko、Moriuchi Masako、Takamatsu Yuki、Inoue Shingo、Urano Takeshi、Bui Minh Xuan、Thai Hung Do、Thi Nguyen Hien-Anh、Anh Dang Duc、Yoshida Lay-Myint、Moriuchi Hiroyuki、Morita Kouichi
    • Journal Title

      Journal of Infection and Public Health

      Volume: 17 Issue: 6 Pages: 1050-1056

    • DOI

      10.1016/j.jiph.2024.04.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K10246
  • [Journal Article] Performance of Fujifilm Dengue NS1 Antigen Rapid Diagnosis Kit Compared to Quantitative Real-Time Polymerase Chain Reaction2024

    • Author(s)
      Ngwe Tun Mya Myat、Kapandji Merveille、Wada Atsuhiko、Yamamoto Ko、Dumre Shyam Prakash、Nwe Khine Mya、Lin Htin、Takamatsu Yuki、Thant Kyaw Zin、Thu Hlaing Myat、Urano Takeshi、Pandey Basu Dev、Morita Kouichi
    • Journal Title

      Pathogens

      Volume: 13 Issue: 9 Pages: 1-11

    • DOI

      10.3390/pathogens13090818

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K02288, KAKENHI-PROJECT-24K10246
  • [Journal Article] Circulating serotypes and genotypes of dengue virus during the 2023 outbreak in Eastern Nepal2024

    • Author(s)
      Bharati Niten、Dumre Shyam Prakash、Shah Yogendra、Nabesima Takeshi、Dhimal Meghnath、Pandey Srijana、Kapandji Merveille、Takamatsu Yuki、Urano Takeshi、Pandey Basu Dev、Morita Kouichi、Ngwe Tun Mya Myat、Pandey Kishor
    • Journal Title

      Journal of Clinical Virology

      Volume: 174 Pages: 1-11

    • DOI

      10.1016/j.jcv.2024.105721

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K02288, KAKENHI-PROJECT-24K10246
  • [Journal Article] C5a stimulation induces caspase-1 activation and mature IL-1β production in human peripheral blood mononuclear cells2023

    • Author(s)
      Fujita Yuya、Matsumoto Haruki、Inada Kenji、Onizawa Michio、Saito Kenji、Sumichika Yuya、Yoshida Shuhei、Temmoku Jumpei、Matsuoka Naoki、Asano Tomoyuki、Sato Shuzo、Machida Takeshi、Migita Kiyoshi
    • Journal Title

      Immunological Medicine

      Volume: 15 Issue: 2 Pages: 1-8

    • DOI

      10.1080/25785826.2023.2292665

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08777, KAKENHI-PROJECT-21K07083, KAKENHI-PROJECT-24K11599
  • [Journal Article] Generation of the novel anti-FXYD5 monoclonal antibody and its application to the diagnosis of pancreatic and lung cancer2023

    • Author(s)
      Hotta Takamasa、Nariai Yuko、Kajitani Naoyo、Kadota Kyuichi、Maruyama Riruke、Tajima Yoshitsugu、Isobe Takeshi、Kamino Hiroki、Urano Takeshi
    • Journal Title

      Biochimie

      Volume: - Pages: 160-169

    • DOI

      10.1016/j.biochi.2023.01.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07635, KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753
  • [Journal Article] Monoclonal Antibody Against Mature Interleukin-18 Ameliorates Colitis in Mice and Improves Epithelial Barrier Function2023

    • Author(s)
      Ikegami Shuji、Maeda Keiko、Urano Takeshi、Mu Jingxi、Nakamura Masanao、Yamamura Takeshi、Sawada Tsunaki、Ishikawa Eri、Yamamoto Kenta、Muto Hisanori、Oishi Akina、Iida Tadashi、Mizutani Yasuyuki、Ishikawa Takuya、Kakushima Naomi、Furukawa Kazuhiro、Ohno Eizaburo、Honda Takashi、Ishigami Masatoshi、Kawashima Hiroki
    • Journal Title

      Inflammatory Bowel Diseases

      Volume: - Issue: 8 Pages: 1353-1366

    • DOI

      10.1093/ibd/izad292

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-21K15920
  • [Journal Article] Generation of antagonistic monoclonal antibodies against the neoepitope of active mouse interleukin (IL)-18 cleaved by inflammatory caspases2022

    • Author(s)
      Uchida Yuki、Nariai Yuko、Obayashi Eiji、Tajima Yoshitsugu、Koga Tomohiro、Kawakami Atsushi、Urano Takeshi、Kamino Hiroki
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 727 Pages: 109322-109322

    • DOI

      10.1016/j.abb.2022.109322

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06049, KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K07635, KAKENHI-PROJECT-20K16443
  • [Journal Article] Extranodal Rosai-Dorfman Disease Involving the Pancreas2022

    • Author(s)
      Otaki Satomi、Kawabata Yasunari、Nishi Takeshi、Hayashi Hikota、Iwahashi Teruaki、Maruyama Riruke、Tajima Yoshitsugu
    • Journal Title

      Pancreas

      Volume: 51 Issue: 6 Pages: e89-e91

    • DOI

      10.1097/mpa.0000000000002089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08753
  • [Journal Article] Romidepsin and tamoxifen cooperatively induce senescence of pancreatic cancer cells through downregulation of FOXM1 expression and induction of reactive oxygen species/lipid peroxidation2022

    • Author(s)
      Okuni Noriko、Honma Yoshio、Urano Takeshi、Tamura Kenji
    • Journal Title

      Molecular Biology Reports

      Volume: - Issue: 5 Pages: 3519-3529

    • DOI

      10.1007/s11033-022-07192-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Journal Article] Kinetics of Anti-SARS-CoV-2 Antibody Response Following Two Doses of the BNT162b2 mRNA Vaccine: A Japanese Single-Center Primary Care Clinic Report Involving Volunteers and Patients with Autoimmune Disease2022

    • Author(s)
      Sugiura Tomoko、Sugiura Hiroaki、Kato Hiroaki、Nariai Yuko、Mizumoto Yuuki、Hanada Kozue、Takahashi Rieko、Hinotubo Yukari、Tanaka Naoko、Sasaki Mutsumi、Eguchi Haruki、Kamino Hiroki、Urano Takeshi
    • Journal Title

      Infectious Disease Reports

      Volume: 15 Issue: 1 Pages: 24-33

    • DOI

      10.3390/idr15010003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K05505, KAKENHI-PROJECT-20K07635, KAKENHI-PUBLICLY-21H00255
  • [Journal Article] Pathological eradication of recurrent metastatic renal cell carcinoma with sarcomatoid component by nivolumab plus ipilimumab combination therapy2021

    • Author(s)
      Sejima Takehiro、Masago Toshihiko、Yoshida Manabu、Nishi Takeshi、Kawabata Yasunari、Tajima Yoshitsugu、Yumioka Tetsuya、Honda Masashi、Takenaka Atsushi
    • Journal Title

      International Cancer Conference Journal

      Volume: 10 Issue: 4 Pages: 285-289

    • DOI

      10.1007/s13691-021-00501-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08753
  • [Journal Article] New Insights into The Pathogenesis of Intrabile Duct Ectopic Hepatocellular Carcinoma: A Case Report and Review of the Literature2021

    • Author(s)
      Nakamura Kosuke、Nishi Takeshi、Hayashi Hikota、Kawabata Yasunari、Araki Asuka、Tajima Yoshitsugu
    • Journal Title

      Archives of Clinical and Medical Case Reports

      Volume: 05 Issue: 03 Pages: 479-482

    • DOI

      10.26502/acmcr.96550383

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08753
  • [Journal Article] Phase II feasibility study of adjuvant chemotherapy with docetaxel/cisplatin/S-1 followed by S-1 for stage III gastric cancer2021

    • Author(s)
      Hirahara Noriyuki、Matsubara Takeshi、Kaji Shunsuke、Yamamoto Tetsu、Hyakudomi Ryoji、Takai Kiyoe、Ishitobi Kazunari、Uchida Yuki、Tajima Yoshitsugu
    • Journal Title

      BMC Cancer

      Volume: 21 Issue: 1 Pages: 1073-1073

    • DOI

      10.1186/s12885-021-08795-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K16443
  • [Journal Article] Chemical map-based prediction of nucleosome positioning using the Bioconductor package nuCpos2021

    • Author(s)
      Kato Hiroaki、Shimizu Mitsuhiro、Urano Takeshi
    • Journal Title

      BMC Bioinformatics

      Volume: 22 Issue: 1 Pages: 322-322

    • DOI

      10.1186/s12859-021-04240-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-19K05957, KAKENHI-PUBLICLY-19H05264, KAKENHI-PROJECT-21K05505, KAKENHI-PROJECT-21K08438, KAKENHI-PUBLICLY-21H00255
  • [Journal Article] Sequence-dependent nucleosome formation in trinucleotide repeats evaluated by in vivo chemical mapping2021

    • Author(s)
      Koji Katsumata, Yuichi Ichikawa, Tomohiro Fuse, Hitoshi Kurumizaka, Akio Yanagida , Takeshi Urano, Hiroaki Kato, Mitsuhiro Shimizu
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 556 Pages: 179-184

    • DOI

      10.1016/j.bbrc.2021.03.155

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05957, KAKENHI-PROJECT-18K05556, KAKENHI-PUBLICLY-19H05264, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-20H00449, KAKENHI-PROJECT-21K05505, KAKENHI-PROJECT-21K08438, KAKENHI-PUBLICLY-21H00255
  • [Journal Article] A safe and simple technique for nasogastric tube insertion in patients with thoracic esophageal cancer surgery2021

    • Author(s)
      Hirahara Noriyuki、Matsubara Takeshi、Kaji Shunsuke、Uchida Yuki、Yamamoto Tetsu、Hyakudomi Ryoji、Takai Kiyoe、Ishitobi Kazunari、Tajima Yoshitsugu
    • Journal Title

      World Journal of Surgical Oncology

      Volume: 19 Issue: 1 Pages: 317-317

    • DOI

      10.1186/s12957-021-02428-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K16443
  • [Journal Article] Accurate prediction of severe postoperative complications after pancreatic surgery: POSSUM vs E‐PASS2021

    • Author(s)
      Hayashi Hikota、Kawabata Yasunari、Nishi Takeshi、Kishi Takashi、Nakamura Kosuke、Kaji Shunsuke、Fujii Yusuke、Tajima Yoshitsugu
    • Journal Title

      Journal of Hepato-Biliary-Pancreatic Sciences

      Volume: 28 Issue: 2 Pages: 156-164

    • DOI

      10.1002/jhbp.839

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08753
  • [Journal Article] Laparoscopic portal branch ligation of the right caudate lobe concomitant with portal vein embolization for planned right hemihepatectomy in advanced hepatobiliary cancers2021

    • Author(s)
      Kawabata Yasunari、Hayashi Hikota、Yoshida Rika、Ando Shinji、Nakamura Kosuke、Kishi Takashi、Nishi Takeshi、Nakamura Megumi、Tajima Yoshitsugu
    • Journal Title

      Langenbeck's Archives of Surgery

      Volume: 406 Issue: 3 Pages: 917-926

    • DOI

      10.1007/s00423-021-02147-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08753
  • [Journal Article] A safe, reliable, and efficient robot-assisted port site closure for robot-assisted gastrectomy2021

    • Author(s)
      Hirahara Noriyuki、Matsubara Takeshi、Kaji Shunsuke、Uchida Yuki、Yamamoto Tetsu、Hyakudomi Ryoji、Zotani Hitomi、Kawakami Koki、Sasaki Yuhei、Tajima Yoshitsugu
    • Journal Title

      Annals of Medicine and Surgery

      Volume: 71 Pages: 103001-103001

    • DOI

      10.1016/j.amsu.2021.103001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K16443
  • [Journal Article] Uric acid-mediated inflammasome activation in IL-6 primed innate immune cells is regulated by baricitinib.2020

    • Author(s)
      Temmoku J, Fujita Y, Matsuoka N, Urano T, Furuya MY, Asano T, Sato S, Matsumoto H, Watanabe H, Kozuru H, Yatsuhashi H, Kawakami A, Migita K.
    • Journal Title

      Mod Rheumatol.

      Volume: 30 Issue: 1 Pages: 1-6

    • DOI

      10.1080/14397595.2020.1740410

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-20K08777
  • [Journal Article] Elucidation of the aberrant 3′ splice site selection by cancer-associated mutations on the U2AF12020

    • Author(s)
      Yoshida Hisashi、Park Sam-Yong、Sakashita Gyosuke、Nariai Yuko、Kuwasako Kanako、Muto Yutaka、Urano Takeshi、Obayashi Eiji
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 4744-4752

    • DOI

      10.1038/s41467-020-18559-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-20H01007
  • [Journal Article] Screening of a Panel of Low Molecular Weight Compounds That Inhibit Synovial Fibroblast Invasion in Rheumatoid Arthritis2020

    • Author(s)
      Sugiura Tomoko、Kamino Hiroki、Nariai Yuko、Murakawa Yohko、Kondo Masahiro、Kawakami Makoto、Ikeda Noboru、Uchio Yuji、Urano Takeshi
    • Journal Title

      The Journal of Immunology

      Volume: 205 Issue: 12 Pages: 3277-3290

    • DOI

      10.4049/jimmunol.1901429

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07635, KAKENHI-PROJECT-20H01007
  • [Journal Article] Gcn2 eIF2α kinase mediates combinatorial translational regulation through nucleotide motifs and uORFs in target mRNAs2020

    • Author(s)
      Chikashige Yuji、Kato Hiroaki、Thornton Mackenzie、Pepper Whitney、Hilgers Madelyn、Cecil Ariana、Asano Izumi、Yamada Haana、Mori Chie、Brunkow Cheyenne、Moravek Carter、Urano Takeshi、Singh Chingakham Ranjit、Asano Katsura
    • Journal Title

      Nucleic Acids Research

      Volume: 48 Issue: 16 Pages: 8977-8992

    • DOI

      10.1093/nar/gkaa608

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05556, KAKENHI-PUBLICLY-19H05264
  • [Journal Article] Nucleus Accumbens-Associated Protein 1 Binds DNA Directly through the BEN Domain in a Sequence-Specific Manner2020

    • Author(s)
      Nakayama Naomi、Sakashita Gyosuke、Nagata Takashi、Kobayashi Naohiro、Yoshida Hisashi、Park Sam-Yong、Nariai Yuko、Kato Hiroaki、Obayashi Eiji、Nakayama Kentaro、Kyo Satoru、Urano Takeshi
    • Journal Title

      Biomedicines

      Volume: 8 Issue: 12 Pages: 608-608

    • DOI

      10.3390/biomedicines8120608

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07307, KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-18K06152, KAKENHI-PROJECT-20H01007
  • [Journal Article] How does Hsp90 function in RNAi-dependent heterochromatin assembly?2019

    • Author(s)
      Kato H, Okazaki K, Urano T.
    • Journal Title

      Current Genetics

      Volume: 65 Issue: 1 Pages: 87-91

    • DOI

      10.1007/s00294-018-0866-0

    • NAID

      120006648413

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556
  • [Journal Article] Chemical map-based prediction of nucleosome positioning using the Bioconductor package nuCpos2019

    • Author(s)
      Kato Hiroaki、Shimizu Mitsuhiro、Urano Takeshi
    • Journal Title

      bioRxiv

      Volume: 2019.12.25 Pages: 888305-888305

    • DOI

      10.1101/2019.12.25.888305

    • Open Access
    • Data Source
      KAKENHI-PROJECT-18K05556, KAKENHI-PUBLICLY-19H05264
  • [Journal Article] Hydroxychloroquine inhibits IL-1β production from amyloid-stimulated human neutrophils.2019

    • Author(s)
      Fujita Y, Matsuoka N, Temmoku J, Furuya MY, Asano T, Sato S, Kobayashi H, Watanabe H, Suzuki E, Urano T, Kozuru H, Yatsuhashi H, Koga T, Kawakami A, Migita K.
    • Journal Title

      Arthritis Res Ther.

      Volume: 21(1) Issue: 1 Pages: 250-250

    • DOI

      10.1186/s13075-019-2040-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-17K08983
  • [Journal Article] Generation and characterization of antagonistic anti-human interleukin (IL)-18 monoclonal antibodies with high affinity: Two types of monoclonal antibodies against full-length IL-18 and the neoepitope of inflammatory caspase-cleaved active IL-18.2019

    • Author(s)
      Nariai Y, Kamino H, Obayashi E, Kato H, Sakashita G, Sugiura T, Migita K, Koga T, Kawakami A, Sakamoto K, Kadomatsu K, Nakakido M, Tsumoto K, Urano T.
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 663 Pages: 71-82

    • DOI

      10.1016/j.abb.2019.01.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H05139, KAKENHI-PROJECT-19H00340, KAKENHI-PROJECT-17H06109
  • [Journal Article] Cancer-related transcription regulator protein NAC1 forms a protein complex with CARM1 for ovarian cancer progression.2018

    • Author(s)
      Nakayama N, Sakashita G, Nariai Y, Kato H, Sinmyozu K, Nakayama JI, Kyo S, Urano T, Nakayama K.
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 47 Pages: 28408-28420

    • DOI

      10.18632/oncotarget.25400

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-18K16771, KAKENHI-PROJECT-18H02946
  • [Journal Article] 2.TH588, an MTH1 inhibitor, enhances phenethyl isothiocyanate-induced growth inhibition in pancreatic cancer cells.2018

    • Author(s)
      Ikejiri F, Honma Y, Kasukabe T, Urano T, Suzumiya J.
    • Journal Title

      Oncol. Lett.

      Volume: 15 Pages: 3240-3244

    • DOI

      10.3892/ol.2017.7713

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10459, KAKENHI-PROJECT-17K08983
  • [Journal Article] Expression of aquaporin 3 and 5 as a potential marker for distinguishing dry mouth from Sjögren’s syndrome2018

    • Author(s)
      Ichiyama T, Nakatani E, Tatsumi K, Hideshima K, Urano T, Nariai Y, Sekine J.
    • Journal Title

      Journal of Oral Science

      Volume: 60 Issue: 2 Pages: 212-220

    • DOI

      10.2334/josnusd.17-0150

    • NAID

      130007398371

    • ISSN
      1343-4934, 1880-4926
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Journal Article] Diacylglycerol kinase δ controls down-regulation of cyclin D1 for C2C12 myogenic differentiation2018

    • Author(s)
      Sakai Hiromichi、Murakami Chiaki、Matsumoto Ken-ichi、Urano Takeshi、Sakane Fumio
    • Journal Title

      Biochimie

      Volume: 151 Pages: 45-53

    • DOI

      10.1016/j.biochi.2018.05.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08271, KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-17H03650, KAKENHI-PROJECT-18J20003
  • [Journal Article] Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate.2018

    • Author(s)
      Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H.
    • Journal Title

      Communications Biology

      Volume: 1 Issue: 1 Pages: 120-120

    • DOI

      10.1038/s42003-018-0121-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-18H02396
  • [Journal Article] Cotylenin A and tyrosine kinase inhibitors synergistically inhibit the growth of chronic myeloid leukemia cells.2018

    • Author(s)
      Ikejiri F, Honma Y, Okada T, Urano T, Suzumiya J.
    • Journal Title

      International Journal of Oncology

      Volume: 52 Pages: 2061-2068

    • DOI

      10.3892/ijo.2018.4350

    • NAID

      120006645822

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Journal Article] RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5.2018

    • Author(s)
      Okazaki K, Kato H, Iida T, Shinmyozu K, Nakayama JI, Murakami Y, Urano T.
    • Journal Title

      Epigenetics & Chromatin

      Volume: 11 Issue: 1 Pages: 26-26

    • DOI

      10.1186/s13072-018-0199-8

    • NAID

      120006651232

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-17H03713
  • [Journal Article] Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography.2018

    • Author(s)
      Sakashita G, Kiyoi H, Naoe T, Urano T.
    • Journal Title

      Sci Rep.

      Volume: 8 Issue: 1 Pages: 4008-4008

    • DOI

      10.1038/s41598-018-22359-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-17K09921
  • [Journal Article] Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo.2017

    • Author(s)
      Fuse T, Katsumata K, Morohoshi K, Mukai Y, Ichikawa Y, Kurumizaka H, Yanagida A, Urano T, Kato H, Shimizu M.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 10 Pages: e0186974-e0186974

    • DOI

      10.1371/journal.pone.0186974

    • NAID

      120006539368

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-17H01408
  • [Journal Article] Japanese apricot extract (MK615) potentiates bendamustine-induced apoptosis via impairment of the DNA damage response in lymphoma cells.2017

    • Author(s)
      Inoue M, Honma Y, Urano T, Suzumiya J.
    • Journal Title

      Oncol Lett.

      Volume: 14 Issue: 1 Pages: 792-800

    • DOI

      10.3892/ol.2017.6219

    • NAID

      120006645824

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Journal Article] The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast.2017

    • Author(s)
      Seo HD, Choi Y, Kim M, Kang K, Urano T, Lee D.
    • Journal Title

      J Biol Chem.

      Volume: 292 Issue: 41 Pages: 17144-17155

    • DOI

      10.1074/jbc.m117.790824

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Journal Article] Precise epitope determination of the anti-vimentin monoclonal antibody V9.2017

    • Author(s)
      Tomiyama L, Kamino H, Fukamachi H, Urano T.
    • Journal Title

      Mol Med Rep.

      Volume: 16 Issue: 4 Pages: 3917-3921

    • DOI

      10.3892/mmr.2017.7102

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Journal Article] A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.2015

    • Author(s)
      Yoshida H, Park S-Y, Oda T, Akiyoshi T, Sato M, Shirouzu M, Tsuda K, Kuwasako K, Unzai S, Muto Y, Urano T, Obayashi E.
    • Journal Title

      Genes Dev.

      Volume: 29 Issue: 15 Pages: 1649-1660

    • DOI

      10.1101/gad.267104.115

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06980, KAKENHI-PROJECT-15K06982, KAKENHI-PROJECT-15K18499, KAKENHI-PUBLICLY-26116519, KAKENHI-PROJECT-25291016, KAKENHI-PROJECT-25291037
  • [Journal Article] Rappsilber J and Allshire RC.: Raf1 is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification2012

    • Author(s)
      Buscaino A, White S, Houston D, Simmer F, Alves F, Diyora PT, Urano T, Bayne E
    • Journal Title

      PLoS Genet.

      Volume: 8

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] DNA : RNA hybrid formation mediates RNAi-directed heterochromatin formation2012

    • Author(s)
      Nakama M, Kawakami K, Kajitani T, Urano T and Murakami Y
    • Journal Title

      Genes Cells

      Volume: 17 Pages: 218-233

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Murakami Y and Nakayama J-I.: Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly2012

    • Author(s)
      Hayashi A, Ishida M, Kawaguchi R, Urano T
    • Journal Title

      Proc. Natl Acad. Sci. USA

      Volume: 109 Pages: 6159-6164

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells2012

    • Author(s)
      Inoko A, Matsuyama M, Goto H, Ohmuro-Matsuyama Y, Hayashi Y, Enomoto M, Ibi M, Urano T, Yonemura S, Kiyono T, Izawa I and Inagaki M.
    • Journal Title

      J. Cell Biol.

      Volume: 197 Pages: 391-405

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen2012

    • Author(s)
      Matsumoto Y, Zhang Q, Akita K, Nakada H, Hamamura K, Tokuda N, Tsuchida A, Matsubara T, Hori T, Okajima T, Furukawa K, Urano T and Furukawa K
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 419 Pages: 7-13

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles2011

    • Author(s)
      Ma N, Matsunaga S, Morimoto A, Sakashita G, Urano T, Uchiyama S and Fukui K
    • Journal Title

      J. Cell Sci

      Volume: 124 Pages: 394-404

    • NAID

      120006994997

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis2011

    • Author(s)
      Ban R, Nishida T and Urano T
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 652-669

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Preparation, characterization and properties of novel covalently surface-functionalized zinc oxide nanoparticles2010

    • Author(s)
      Sato M, Harada H, Morito S, Fujita Y, Shimosaki S, Urano T and Nakamura M
    • Journal Title

      Appl. Surf. Sci

      Volume: 256 Pages: 4497-4501

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast2010

    • Author(s)
      Simmer F, Buscaino A, Kos-Braun IC, Kagansky A, Boukaba A, Urano T, Kerr AR and Allshire RC
    • Journal Title

      EMBO Rep

      Volume: 11 Pages: 112-118

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Glycosylphosphatidylinositol-anchored arginine-specific ADP-ribosyltransferase7.1(Art7.1) on chicken B cells: the possible role of Art7 in B cell receptor signalling and proliferation.2009

    • Author(s)
      Terashima M, Takahashi M, Shimoyama M,Tanigawa Y, Urano T and Tsuchiya M
    • Journal Title

      Mol Cell Biochem 320

      Pages: 470-478

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity2009

    • Author(s)
      Arimura N, Hattori A, Kimura T, Nakamuta SI, Funahashi Y, Hirotsune S, Furuta K, Urano T, Toyoshima YY, Kaibuchi K
    • Journal Title

      J Neurochem

      Volume: 111 Pages: 380-390

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases2009

    • Author(s)
      Ban R, Matsuzaki H, Akashi T, Sakashita G, Taniguchi H, Park S-Y, Tanaka H, Furukawa K and Urano T
    • Journal Title

      J. Biol. Chem

      Volume: 284 Pages: 28367-28381

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres2009

    • Author(s)
      Kagansky A, Folco HD, Almeida R, Pidoux AL, Boukaba A, Simmer F, Urano T, Hamilton GL and Allshire RC
    • Journal Title

      Science

      Volume: 324 Pages: 1716-1719

    • Data Source
      KAKENHI-PROJECT-21390081
  • [Journal Article] Phosphorylation of Swi6/HP1 regulates transcriptional gene silencing at heterochromatin.2009

    • Author(s)
      Shimada A, Dohke K, Sadaie M, Shinmyozu K,Nakayama J, Urano T and Murakami Y
    • Journal Title

      Genes Dev. 23

      Pages: 18-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Cdc2p controls the forkhead transcription factor Fkh2p by phosphorylation during sexual differentiation in fission yeast.2008

    • Author(s)
      Shimada M, Yamada-Namikawa C,Murakami-Tonami Y, Yoshida T, Nakanishi M, Urano T, and Murakami H
    • Journal Title

      EMBO J 27

      Pages: 132-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Heterochromatin and RNAi Are Required to Establish CENP-A Chromatin at Centromeres.2008

    • Author(s)
      Folco HD, Pidoux AL, Urano T, and Allshire RC
    • Journal Title

      Science 319

      Pages: 94-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Fission yeast chromatin assembly factor 1 assists in the replication-coupled maintenance of heterochromatin.2008

    • Author(s)
      Dohke K, Miyazaki S, Tanaka K, Urano T,Grewal SI and Murakami Y
    • Journal Title

      Genes Cells 13

      Pages: 1027-1043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Heterochromatin and RNAi are required to establish CENP-A chromatin at centromeres.2008

    • Author(s)
      Folco, H.D., Pidoux, A.L., Urano, T., Allshire, R.C.
    • Journal Title

      Science 319

      Pages: 94-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.2008

    • Author(s)
      Kondo Y, Shen L, Cheng AS, Ahmed S,Boumber Y, Charo C, Yamochi T, Urano T,Furukawa K, Kwabi-Addo B, Gold DL,Sekido Y, Huang TH and Issa JP
    • Journal Title

      Nature Genet 40

      Pages: 741-750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin.2007

    • Author(s)
      Trewick SC, Minc E, Antonelli R, Urano T,and Allshire RC
    • Journal Title

      EMBO J. 26

      Pages: 4670-4682

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.2007

    • Author(s)
      Nakashima H, Hamamura K, Houjou T,Taguchi R, Yamamoto N, Mitsudo K,Tohnai I, Ueda M, Urano T, Furukawa K,Furukawa K
    • Journal Title

      Cancer Sci 98

      Pages: 512-520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Role of DNA methylation and histone H3 Lysine 27 methylation in tissue-specific imprinting of mouse Grb10.2007

    • Author(s)
      Yamasaki-Ishizaki Y, Kayashima T,Mapendano CK, Soejima H, Ohta T,Masuzaki H, Kinoshita A, Urano T,Yoshiura KI, Matsumoto N, Ishimaru T,Mukai T, Niikawa N and Kishino T
    • Journal Title

      Mol. Cell. Biol. 27

      Pages: 732-742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Analysis of the role of Aurora B on the chromosomal targeting of condensin I.2007

    • Author(s)
      Takemoto A, Murayama A, Katano M,Urano T, Furukawa K, Yokoyama S,Yanagisawa J, Hanaoka F and Kimura K
    • Journal Title

      Nucleic Acids Res 35

      Pages: 2403-2412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Gene amplification and overexpression of PRDM14 in breast cancers.2007

    • Author(s)
      Nishikawa N, Toyota M, Suzuki H,Honma T, Fujikane T, Ohmura T,Nishidate T, Ohe-Toyota M, Maruyama R,Sonoda T, Sasaki Y, Urano T, Imai K,Hirata K, and Tokino T
    • Journal Title

      Cancer Res 67

      Pages: 9649-9657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Nucleophosmin (NPM): A versatile molecule associated with hematological malignancies.2006

    • Author(s)
      Naoe T, Suzuki T, Kiyoi H and Urano T
    • Journal Title

      Cancer Sci 97

      Pages: 963-969

    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.2006

    • Author(s)
      Goto H, Kiyono T, Tomono Y, Kawajiri A, Urano T, Furukawa K, Nigg EA, Inagaki M.
    • Journal Title

      Nature Cell Biol. 8

      Pages: 180-187

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Journal Article] Phospho-regulation of human Protein Kinase Aurora-A: Analysis using anti-phospho-Thr288 monoclonal antibodies.2006

    • Author(s)
      Ohashi S, Sakashita G, Ban R, Nagasawa M, Matsuzaki H, Murata Y, Taniguchi H,Shima H, Furukawa K and Urano T
    • Journal Title

      Oncogene 25

      Pages: 7691-7702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KvDMR1 in colorectal cancers.2006

    • Author(s)
      Nakano S, Murakami K, Meguro M, Soejima H, Higashimoto K, Urano T,Kugoh H, Mukai T, Ikeguchi M and Oshimura M
    • Journal Title

      Cancer Sci 97

      Pages: 1147-1154

    • NAID

      10019376824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Metastatic potential of mouse Lewis lung cancer cells is regulated via ganglioside GM1 by modulating the matrix metalloprotease-9 localization in lipid rafts.2006

    • Author(s)
      Zhang Q, Furukawa K, Chen HH, Sakakibara T, Urano T and Furukawa K
    • Journal Title

      J. Biol. Chem 281

      Pages: 18145-18155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Nucleophosmin: a versatile molecule associated with hematological malignancies.2006

    • Author(s)
      Naoe, T., Suzuki, T., Kiyoi, H., Urano, T.
    • Journal Title

      Cancer Sci 97

      Pages: 963-969

    • NAID

      10019377506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.2006

    • Author(s)
      Goto H, Kiyono T, Tomono Y, Kawajiri A, Urano T, Furukawa K, Nigg EA and Inagaki M
    • Journal Title

      Cell Biol 8

      Pages: 180-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.2006

    • Author(s)
      Goto, H., Kiyono, T., Tomono, Y., Kawajiri, A., Urano, T., Furukawa, K., Nigg, EA., Inagaki M.
    • Journal Title

      Nat.Cell Biol. 8

      Pages: 180-187

    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins.2006

    • Author(s)
      Okuda T, Tokuda N, Numata S, Ito M, Ohta M, Kawamura K, Wiels J, Urano T, Tajima O, Furukawa K and Furukawa K
    • Journal Title

      J. Biol. Chem 281

      Pages: 10230-10235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Journal Article] Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.2005

    • Author(s)
      Hamamura K, Furukawa K, Hayashi T, Hattori T, Nakano J, Nakashima H, Okuda T, Mizutani H, Hattori H, Ueda M, Urano T, Lloyd KO, Furukawa K.
    • Journal Title

      Proc Natl Acad Sci USA 102

      Pages: 11041-11046

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Journal Article] Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes : identification of an aneuploidy-promoting property.2005

    • Author(s)
      Nguyen HG, Chinnappan D, Urano T, Ravid K.
    • Journal Title

      Mol Cell Biol 25

      Pages: 4977-4992

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Journal Article] Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres.2005

    • Author(s)
      Kanoh, J., Sadaie, M., Urano, T., Ishikawa, F.
    • Journal Title

      Curr Biol 15

      Pages: 1808-1819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.2005

    • Author(s)
      Yamasaki Y, Kayashima T, Soejima H, Kinoshita A, Yoshiura KI, Matsumoto N, Ohta T, Urano T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Kishino T.
    • Journal Title

      Hum Mol Genet 14

      Pages: 2511-2520

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Journal Article] Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.2005

    • Author(s)
      Yamasaki, Y., Kakashima, T., Soejima, H., Kinoshi ta, A., Yoshiura, K., Matsumoto, N., Ohta, T., Urano, T., Masuzaki, H., Ishimaru, T., Mukai, T., Niikawa, N., Kishino, T.
    • Journal Title

      Hum.Mol.Genet. 14

      Pages: 2511-2520

    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] RNA polymerase II is required for RNAi-dependent heterochromatin assembly.2005

    • Author(s)
      Kato, H., Goto, D.B., Martienssen, R.A., Urano, T., Furukawa, K., Murakami, Y.
    • Journal Title

      Science 309

      Pages: 467-469

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes : identification of an aneuploidy-promoting property.2005

    • Author(s)
      Nguyen, HG., Chinnappan, D., Urano, T., Ravid, K.
    • Journal Title

      Mol.Cell Biol. 25

      Pages: 4977-4992

    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] RNA polymerase II is required for RNAi-dependent heterochromatin assembly.2005

    • Author(s)
      Kato H, Goto DB, Martienssen RA, Urano T, Furukawa K, Murakami Y.
    • Journal Title

      Science 309

      Pages: 467-469

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Journal Article] Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres.2005

    • Author(s)
      Kanoh J, Sadaie M, Urano T, Ishikawa F.
    • Journal Title

      Curr.Biol. 15

      Pages: 1808-1819

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Journal Article] Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.2005

    • Author(s)
      Hamamura, K., Furukawa, K., Hayashi, T., Hattori, T., Nakano, J., Nakashima, H., Okuda, T., Mizutani, H., Hattori, H., Ueda, M., Urano, T., Lloyd, KO., Furukawa, K
    • Journal Title

      Proc.Natl.Acad.Sci. U S A. 102

      Pages: 11041-11046

    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] RNA polymerase II is required for RNAi-dependent heterochromatin assembly.2005

    • Author(s)
      Kato, H., Goto, DB., Martienssen, RA., Urano, T., Furukawa, K., Murakami, Y.
    • Journal Title

      Science 309

      Pages: 467-469

    • Data Source
      KAKENHI-PROJECT-17013043
  • [Journal Article] Telomere-Binding Protein Taz1 Establishes Swi6 Heterochromatin Independently of RNAi at Telomeres.2005

    • Author(s)
      Kanoh, J., Sadaie, M., Urano, T., Ishikawa F.
    • Journal Title

      Curr.Biol. 15

      Pages: 1808-1819

    • Data Source
      KAKENHI-PROJECT-17013043
  • [Patent] 間質性肺疾患の治療薬2024

    • Inventor(s)
      川上純、古賀智裕 、浦野健、成相裕子、他
    • Industrial Property Rights Holder
      川上純、古賀智裕 、浦野健、成相裕子、他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2024
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Patent] 活性型IL-18検出キット、及び検査方法2023

    • Inventor(s)
      浦野健、加美野宏樹、成相裕子、川上純、古賀智裕、他
    • Industrial Property Rights Holder
      浦野健、加美野宏樹、成相裕子、川上純、古賀智裕、他
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-195765
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Patent] ワクチン組成物2021

    • Inventor(s)
      勝又 徹、浦野 健、成相 裕子、加美野 宏樹、秋吉 一成、他
    • Industrial Property Rights Holder
      旭化成(株)、島根大学、京都大学、三重大学、長崎大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-559206
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Patent] 活性型インターロイキンー18タンパク質のネオエピトープを認識する抗体、及びその応用2021

    • Inventor(s)
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Holder
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K07635
  • [Patent] 活性型インターロイキンー18タンパク質のネオエピトープを認識する抗体、及びその応用2021

    • Inventor(s)
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Holder
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K07635
  • [Patent] 活性型インターロイキンー18タンパク質のネオエピトープを認識する抗体、及びその応用2021

    • Inventor(s)
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Holder
      株式会社 mAbProtein
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2021
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Patent] ワクチン組成物2021

    • Inventor(s)
      加美野 宏樹、成相 裕子、浦野 健(他6人)
    • Industrial Property Rights Holder
      旭化成(株)、島根大学、京都大学、三重大学、長崎大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-204470
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K07635
  • [Patent] 活性型インターロイキンー18タンパク質のネオエピトープを認識する抗体、及びその応用2020

    • Inventor(s)
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Holder
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-559206
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K07635
  • [Patent] 検出感度の高いインターロイキンー18タンパク質に対する抗体およびその応用2019

    • Inventor(s)
      浦野 健、成相 裕子、尾林 栄治、加美野 宏樹
    • Industrial Property Rights Holder
      株式会社 mAbProtein
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Patent] 活性型インターロイキンー18タンパク質のネオエピトープを認識する抗体、及びその応用2019

    • Inventor(s)
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Holder
      株式会社 mAbProtein
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Patent] 活性型インターロイキンー18タンパク質のネオエピトープを認識する抗体、及びその応用2018

    • Inventor(s)
      浦野 健、成相 裕子、加美野 宏樹、尾林 栄治
    • Industrial Property Rights Holder
      国立大学法人島根大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-226667
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Patent] 検出感度が向上した、炎症性サイトカイン IL-18 タンパク質に対する新規抗体およびその応用2018

    • Inventor(s)
      浦野 健、成相 裕子、尾林 栄治、加美野 宏樹
    • Industrial Property Rights Holder
      国立大学法人島根大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-072006
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Patent] インフルエンザウイルスのRNA依存性RNAポリメラーゼのPB2サブユニットに対するモノクローナル抗体2014

    • Inventor(s)
      朴三用、浦野健、杉山佳奈子
    • Industrial Property Rights Holder
      朴三用、浦野健、杉山佳奈子
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-068824
    • Filing Date
      2014-03-28
    • Acquisition Date
      2015-10-13
    • Data Source
      KAKENHI-PROJECT-25291016
  • [Patent] インフルエンザウイルスのRNA依存性RNAポリメラーゼのPB2サブユニットに対するモノクローナル抗体2014

    • Inventor(s)
      朴三用、杉山佳奈子、成相裕子、浦野健
    • Industrial Property Rights Holder
      朴三用、杉山佳奈子、成相裕子、浦野健
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-068824
    • Filing Date
      2014-04-10
    • Data Source
      KAKENHI-PROJECT-25291016
  • [Patent] 新規モノクローナル抗体、及びそのタグ抗体としての利用2012

    • Inventor(s)
      浦野健、辰巳香澄、関根浄治
    • Industrial Property Rights Holder
      島根大学
    • Filing Date
      2012-03-13
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Patent] 新規モノクローナル抗体、及びそのタグ抗体としての利用2012

    • Inventor(s)
      浦野健、辰巳香澄、関根浄治
    • Industrial Property Rights Holder
      島根大学
    • Filing Date
      2012-03-13
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Patent] 物質相互作用をリアルタイムに可視化する技術2011

    • Inventor(s)
      岡崎宏亮、成相裕子、加藤太陽、浦野健
    • Industrial Property Rights Holder
      島根大学
    • Industrial Property Number
      2011-076772
    • Filing Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Patent] 新規モノクローナル抗体、及びそのタグ抗体としての利用2011

    • Inventor(s)
      浦野健、辰巳香澄
    • Industrial Property Rights Holder
      島根大学
    • Industrial Property Number
      2011-055953
    • Filing Date
      2011-03-14
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Patent] オーロラAタンパク質の活性調節剤及びその利用2005

    • Inventor(s)
      浦野 健, 古川鋼一
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      2005-336775
    • Filing Date
      2005-11-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Patent] オーロラAタンパク質の活性調節剤及びその利用2005

    • Inventor(s)
      浦野 健, 古川 鋼一
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      2005-336775
    • Filing Date
      2005-11-22
    • Data Source
      KAKENHI-PROJECT-16590222
  • [Presentation] ヒト活性型IL-18を高感度に検出する新規ELISAの開発とその応用2023

    • Author(s)
      加美野 宏樹、成相 裕子、前田 啓子、川嶋 啓揮、浦野 健
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Presentation] A chimeric chemical model revealed asymmetric DNA pattern in transcribed nucleosomes2022

    • Author(s)
      Kato H, Shimizu M and Urano T
    • Organizer
      The 30th Hot Spring Harbor International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Presentation] ヒト膵がん細胞株MIA PaCa-2は栄養飢餓によりインターロイキン-18活性化を伴うパイロトーシスを誘導し、この現象は抗がん剤5-フルオロウラシルによって増強される2022

    • Author(s)
      加美野宏樹、田島義証、浦野健
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K07635
  • [Presentation] 活性化型マウスIL-18のネオエピトープに対する機能阻害モノクローナル抗体の作製とその評価方法の開発2022

    • Author(s)
      成相 裕子, 内田 有紀, 尾林 栄治, 田島 義証, 古賀 智裕, 川上 純, 浦野 健, 加美野 宏樹
    • Organizer
      第95回 日本生化学会
    • Data Source
      KAKENHI-PROJECT-21K08753
  • [Presentation] 活性化型マウスIL-18のネオエピトープに対する機能阻害モノクローナル抗体の作製とその評価方法の開発2022

    • Author(s)
      成相裕子、内田有紀、尾林栄治、田島義証、古賀智裕、川上純、浦野健、加美野宏樹
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K07635
  • [Presentation] A chimeric chemical model revealed asymmetric DNA pattern in transcribed nucleosomes2022

    • Author(s)
      Kato H, Shimizu M, Urano T
    • Organizer
      The 30th Hot Spring Harbor International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05556
  • [Presentation] 活性化型マウスIL-18のネオエピトープに対する機能阻害モノクローナル抗体の作製とその評価方法の開発2022

    • Author(s)
      成相 裕子, 内田 有紀, 尾林 栄治, 田島 義証, 古賀 智裕, 川上 純, 浦野 健, 加美野 宏樹
    • Organizer
      第95回 日本生化学会
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Presentation] ヒト膵がん細胞株MIA PaCa-2は栄養飢餓によりインターロイキン-18活性化を伴うパイロトーシスを誘導し、この現象は抗がん剤5-フルオロウラシルによって増強される2022

    • Author(s)
      加美野宏樹、田島義証、浦野健
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K08753
  • [Presentation] 元外科医の基礎研究者がモノクローナル抗体作製の趣味が高じて、ベンチャーを作ってしまいました2022

    • Author(s)
      浦野健
    • Organizer
      第95回 日本生化学会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Presentation] Development of Biopharmaceuticals using monoclonal antibodies2022

    • Author(s)
      Urano T
    • Organizer
      2nd Nagoya University - Chittagong University Joint Biochemistry Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Presentation] ヒト膵がん細胞株MIA PaCa-2は栄養飢餓によりインターロイキン-18活性化を伴うパイロトーシスを誘導し、この現象は抗がん剤5-フルオロウラシルによって増強される2022

    • Author(s)
      加美野宏樹、田島義証、浦野健
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Presentation] フルオロウラシル処理は低栄養培養下での膵がん細胞におけるIL-18活性化を増強する2021

    • Author(s)
      加美野宏樹、内田有紀、田島義証、浦野健
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08438
  • [Presentation] フルオロウラシル処理は低栄養培養下での膵がん細胞におけるIL-18活性化を増強する2021

    • Author(s)
      加美野宏樹、内田有紀、田島義証、浦野健
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K07635
  • [Presentation] ケミカルハイブリッドモデルによるヌクレオソーム配置予測2021

    • Author(s)
      加藤太陽、清水光弘、浦野健
    • Organizer
      第93回日本遺伝学会大会
    • Data Source
      KAKENHI-PROJECT-18K05556
  • [Presentation] ケミカルマップに基づくヌクレオソームDNAの相性予測2021

    • Author(s)
      加藤太陽、清水光弘、浦野健
    • Organizer
      第14回エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18K05556
  • [Presentation] 塩基構成から眺めるクロマチン2019

    • Author(s)
      加藤太陽、浦野健
    • Organizer
      日本遺伝学会第91回大会
    • Data Source
      KAKENHI-PROJECT-18K05556
  • [Presentation] 成人スチル病患者血清中における活性型炎症性サイトカインIL-18の可視化を可能とした新規モノクローナル抗体の作製2019

    • Author(s)
      浦野 健、成相 裕子、尾林 栄治、加美野 宏樹、右田 清志、川上 純
    • Organizer
      第40回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Presentation] (教育講演)モノクローナル抗体を用いた炎症性疾患に対するバイオ医薬品開発2019

    • Author(s)
      浦野 健
    • Organizer
      第40回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Presentation] 患者血清中における活性型炎症性サイトカインIL-18の可視化を可能とした新規モノクローナル抗体の作製2019

    • Author(s)
      浦野 健
    • Organizer
      第59回日本リンパ網内系学会総会
    • Data Source
      KAKENHI-PROJECT-17K08983
  • [Presentation] Training a dHMM with a chemical map improved accuracy of nucleosome positioning prediction in yeasts2018

    • Author(s)
      Kato H and Urano T
    • Organizer
      Cold Spring Harbor Laboratory Meeting: Epigenetics & Chromatin
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05556
  • [Presentation] Preliminary study on the efficacy of conversion surgery following intensive chemotherapy for initially unresectable pancreatic cancer.2017

    • Author(s)
      Kishi Takashi, Kawabata Yasunari, Nishi Takeshi, Hayashi Hikota, Tajima Yoshitsugu
    • Organizer
      International association of pancreatology/Latin America pancreatic study group Joint Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10595
  • [Presentation] Assessment of predictive accuracy of postoperative compolication in pancreatic surgery: POSSUM vs E-PASS.2017

    • Author(s)
      Hayashi Hikota, Kawabata Yasunari, Nishi Takeshi, Kishi Takashi, Tajima Yoshitsugu
    • Organizer
      International association of pancreatology/Latin America pancreatic study group Joint Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10595
  • [Presentation] Efficacy of adjuvant chemoratiation therapy on survival in patients with curative resected pancreatic cancer.2017

    • Author(s)
      Kawabata Yasunari, Hayashi Hikota, Nishi Takeshi, Kishi Takashi, Tajima Yoshitsugu.
    • Organizer
      International association of pancreatology/Latin America pancreatic study group Joint Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10595
  • [Presentation] Biological and spatial regulation of transcriptional regulatory protein NAC-12012

    • Author(s)
      Urano T.
    • Organizer
      Tufts University
    • Place of Presentation
      Boston, USA(招待講演)
    • Year and Date
      2012-03-13
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] Biological and spatial regulation of transcriptional regulatory protein NAC-12012

    • Author(s)
      Urano T
    • Organizer
      Tufts University
    • Place of Presentation
      Boston, USA
    • Year and Date
      2012-03-13
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] 転写制御因子NAC1の細胞内動態と機能解析2010

    • Author(s)
      浦野健
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      ラフォーレ修善寺(静岡)
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] 転写制御因子NAC1の細胞内動態と機能解析2010

    • Author(s)
      浦野健
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      静岡
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] SUMO化による分裂期キナーゼAuroraの制御2010

    • Author(s)
      浦野健
    • Organizer
      第8回SUMO研究会
    • Place of Presentation
      筑波
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] The spatial regulation of a transcriptional regulator NAC-1.2010

    • Author(s)
      Urano T
    • Organizer
      The 1st International Worksh op on Structural Epigenomics
    • Place of Presentation
      Riken Yokohama Institute Koryuto Hall(Y okohama)
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] Biological and domain analysis of transcriptional regulatory prote in NAC-12010

    • Author(s)
      Urano T.
    • Organizer
      The 6^<th> International Forum on Oxidative Stress and Aging
    • Place of Presentation
      Nagoya Congress Center(Nagoya)
    • Year and Date
      2010-09-07
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] Biological and domain analysis of transcriptional regulatory protein NAC-1.2010

    • Author(s)
      Urano T.
    • Organizer
      The 6^<th> International Forum on Oxidative Stress and Aging
    • Place of Presentation
      Nagoya(招待講演)
    • Year and Date
      2010-09-07
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] The spatial regulation of a transcriptional regulator NAC-1.2010

    • Author(s)
      Urano T.
    • Organizer
      The 1st International Workshop on Structural Epigenomics
    • Place of Presentation
      Yokohama(招待講演)
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] SUMO化による分裂期キナーゼAuroraの制御2010

    • Author(s)
      浦野健
    • Organizer
      第8回SUMO研究会
    • Place of Presentation
      筑波大学(筑波)
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-21390081
  • [Presentation] Calcium/Calmodulin Binds to and Inhibits Aurora-A Kinase Activity at Anaphase.2008

    • Author(s)
      Takeshi Urano
    • Organizer
      48^th ASCB
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2008-12-14
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Presentation] 細胞周期を制御する分裂期キナーゼAurora2007

    • Author(s)
      浦野 健
    • Organizer
      第16回日本アポトーシス研究会
    • Place of Presentation
      千葉 東邦大学
    • Year and Date
      2007-08-04
    • Data Source
      KAKENHI-PROJECT-17013043
  • [Presentation] 細胞周期を制御する分裂期キナーゼAurora2007

    • Author(s)
      浦野 健
    • Organizer
      第16回日本アポトーシス研究会
    • Place of Presentation
      千葉
    • Year and Date
      2007-08-04
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Presentation] 細胞周期を制御する分裂期キナーゼAurora2007

    • Author(s)
      浦野 健
    • Organizer
      第16回日本アポトーシス研究会(招待講演)
    • Place of Presentation
      千葉
    • Year and Date
      2007-08-04
    • Data Source
      KAKENHI-PROJECT-18390083
  • [Presentation] Calcium/Calmodulin Binds to and Inhibits Aurora-A Kinase Activity at Anaphase2000

    • Author(s)
      Reiko Ban and Takeshi Urano
    • Organizer
      48^<th> ASCB
    • Place of Presentation
      San Francisco (USA)
    • Data Source
      KAKENHI-PROJECT-18390083
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    # of Collaborated Products: 0 results
  • 19.  Park Sam-Yong (20291932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  Sugiyama Kanako (20623226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TAJIMA Orie (10362237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Kato Hiroaki (40548418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 23.  内田 有紀 (60868719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 24.  増本 純也 (20334914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  小迫 英尊 (10291171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  竹田 浩之 (40609393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  岸田 大 (50467180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  山中 聡士 (50853884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  小谷 仁司 (10594640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  ヌグエ・トン ミャ・ミャッ (90772583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 31.  森田 公一 (40182240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 32.  野津 雅和 (50709144)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  NAGATA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  粕壁 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  雲財 悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  高松 由基
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 37.  堺 弘道
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  清水 光弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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