FURUKAWA Keiko 古川圭子

Researcher Number	50260732
Affiliation (Current)	2020: 中部大学, 生命健康科学部, 教授
Affiliation (based on the past Project Information) *help	2006 – 2020: Chubu University, College of life and health sciences, Professor, 生命健康科学部, 教授 2005: 名古屋大学, 大学院医学系研究科, 講師 2002 – 2005: 名古屋大学, 大学院・医学系研究科, 講師 2001: 名古屋大学, 大学院・医学研究科, 講師 2001: Graduate School of Medicine, Nagoya University Assistant Professor, 大学院・医学部研究科, 講師 … More
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Biological Sciences / General medical chemistry / Pathological medical chemistry / Basic Section 48040:Medical biochemistry-related Except Principal Investigator Biological Sciences / General medical chemistry / Pathological medical chemistry / General medical chemistry / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 48:Biomedical structure and function and related fields
Keywords	Principal Investigator ガングリオシド / 糖鎖合成酵素遺伝子 / GD3 / GM2 / メラノーマ / 酸性スフィンゴ糖脂質 / スフィンゴ糖脂質 / プロモーター / 遺伝子発現 / ganglioside … More Except Principal Investigator ガングリオシド / 糖転移酵素 / ノックアウト / ニューロン / 糖脂質 / 変性 / スフィンゴ糖脂質 / ganglioside / neuron / PC12 / メラノーマ / TrkA / 増殖 / 遺伝子発現 / GD3 / ミクロドメイン / ラフト / シグナル / グリア / ターゲッティング / degeneration / 神経変性 / クラスター / 人癌特異抗原 / 自家癌 / キラーT細胞クローン / T細胞抗原レセプター / 胃癌抗原 / 原癌遺伝子 / イムノプロテアソーム / 癌関連糖鎖 / メラノサイト / 神経成長因子 / プロラクチン / 保育行動 / ラット / マウス / 脳内受容体 / ノックアウトマウス / 神経回路 / アポトーシス / PDGF / バリヤー / 脳血液関門 / サイトカイン / ブラッドブレインバリヤー / 初代培養 / 末梢神経 / DNAチップ / DNAアレイ / GB3 / 糖鎖合成酵素 / 糖鎖遺伝子 / 糖鎖 / クローニング / トランスジェニック / スィンゴ糖脂質 / リモデリング / ジーンノックアウト / トランスフェクション / carbohydrate / knock-out / cloning / 小脳 / プルキンエ細胞 / 後根神経節 / サブトラクション / 脊髄 / プロキンエ細胞 / glysyltransferase / targeting / neuradegeneration / cerebeilum / purkinje cell / dorsal root ganglia / 神経 / 炎症 / 補体 / アセチルコリン / セロトニン / knockout / glycolipid / nerve / raft / inflammation / 膜分子 / 複合体 / 微小環境 / 脂質ラフト / 細胞外顆粒 / セラミド / エクソソーム / 細胞外分泌小胞 / サブセット Less

Dynamics of microenvironmental regulation by extracellular vesicles with carbohydrates and molecular cluster formationOngoing
- Principal Investigator
  
  古川鋼一
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Chubu University
Regulatory mechanisms for signals on cell membrane and under microenvironment by complex of glycosphingolipids and membrane moleculesOngoing
- Principal Investigator
  
  古川鋼一
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Chubu University
癌関連スフィンゴ糖脂質と膜分子間の相互作用の時空間的動態と癌性形質増強機構の解析Principal InvestigatorOngoing
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Chubu University
Regulatory mechanisms for inflammatory responses and expression of cancer-associated glycosyltransferase genes by microenvironment factors, and their implicationsPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chubu University
Spatio-temporal analysis of cell membrane molecules involved in the enhancement of malignant properties by glycosphingolipidsPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chubu University
The molecular mechanisms of the convergence in the early stage of the cell growth and adhesion signalings enhanced by glycosphingolipidsPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chubu University
Roles of glycosphinglipids in converging process of the cell signals of proliferation and adhesion in cancer cells.Principal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chubu University
Mechanisms for the biosignal regulation with glycosphingolipids and their redundancy
- Principal Investigator
  
  FURUKAWA Kouichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
The mechanisms for the neuronal degeneration in the retina of the mutant mice lacking b-series acidic glycosphingolipids.Principal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
スフィンゴ糖脂質によるraftの構造調節と増殖・分化シグナルの制御機構Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
糖鎖合成系遺伝子の発現プロフィールと多型性解析による病態解明
- Principal Investigator
  
  古川鋼一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Analysis of the mechanism for neuronal degeneration and regeneration and responsible gene using the mutant mice disrupted of complex gangliosidePrincipal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
癌特異的糖転移酵素遺伝子を標的とする癌治療法の開発Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
血液-脳バリヤーとしての酸性スフィンゴ糖脂質の機能の解析
- Principal Investigator
  
  古川鋼一
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
Analysis of in vivo function of glycosphingolipids with glycosylation mutant mice
- Principal Investigator
  
  FURUKAWA Koichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
糖鎖合成系酵素遺伝子群の発現モードと多型性の解析に基づく疾患病態の解明Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
膜ミクロドメインにおけるスフィンゴ糖脂質の細胞増殖と分化のシグナル制御機構
- Principal Investigator
  
  古川鋼一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Molecular mechanism for the maintenance and repair of nervous sptem with acidicPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
GD3合成酵素遺伝子のヒトメラノーマ特異的発現機構の解析とその治療応用Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
CD3合成酵素遺伝子により誘導される細胞増殖シグナルの機構解析
- Principal Investigator
  
  古川鋼一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
糖鎖合成酵素遺伝子の癌細胞特異的発現制御領域の解析とその遺伝子治療への応用Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
The regulation of growth and differentiation signales of nerve cells bar sphingoglycolipids.
- Principal Investigator
  
  FURUKAWA Koichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Molecular mechanisms for the regulation of T cell signals by sphingoglycolipidsPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
ガングリオシド糖鎖のリモデリングによる細胞増殖制御機構の解析
- Principal Investigator
  
  古川鋼一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
糖鎖合成酵素遺伝子の癌細胞特異的発現制御領域の解析とその遺伝子治療への応用Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
プロラクチンによる保育行動誘導の分子基盤・脳内受容体遺伝子発現と神経回路の解析
- Principal Investigator
  
  中島邦夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
ガングリオシド糖鎖合成酵素遺伝子の癌細胞特異的発現機構と関連転写因子の解析Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Gene therapy using promoters of glycosyltransferase genes which code tumor specific carbohydrate antigens.Principal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
  Mie University
ガングリオシド糖鎖合成酵素遺伝子の癌細胞特異的発現機構と関連転写因子の解析Principal Investigator
- Principal Investigator
  
  古川圭子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagasaki University
ヒト自家癌拒絶の免疫学的分子機構
- Principal Investigator
  
  菊地浩吉
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Analvsis of localization of a glycosyltransferase and transfort of glycolipids by gene manipulationPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Keiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki University

[Book] 糖鎖生物学、生命現象と糖鎖情報　免疫と糖鎖(I) 免疫調節2020
- Author(s)
  大海雄介、古川鋼一
- Publisher
  名古屋大学出版会
- ISBN
  9784815809812
- Data Source
  KAKENHI-PROJECT-19K22518
[Book] 糖鎖生物学、生命現象と糖鎖情報神経と糖鎖(II) 神経機能2020
- Author(s)
  古川鋼一、大海雄介、田島織絵、古川圭子
- Publisher
  名古屋大学出版会
- Data Source
  KAKENHI-PROJECT-19K22518
[Book] 糖鎖の新機能開発・応用ハンドブック2015
- Author(s)
  古川鋼一、近藤裕史、北村　勝、古川圭子、大川祐樹、松本康之、大海雄介、橋本　登、山内祥生、他
- Total Pages
  678
- Publisher
  （株）エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-26460404
[Book] Glycoscience: Biology and Medicine2014
- Author(s)
  Koichi Furukawa, Yuhsuke Ohmi, Yuki Ohkawa, Noboru Hashimoto, Yoshio Yamauchi, Orie Tajima, Keiko Furukawa
- Total Pages
  1568
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26460404
[Book] Lipid Rafts (Editor:Dan Sillence), The Role of Glycosphingolipids in Lipid Rafts2013
- Author(s)
  Koichi Furukawa, Yusuke Ohmi, Yuji Kondo, Yuki Ohkawa, Noboru Hashimoto, Orie Tajima, Keiko Furukawa.
- Publisher
  Nova Science Publishers Inc.
- Data Source
  KAKENHI-PROJECT-23590371
[Book] シグナル伝達研究最前線2012糖鎖修飾によるシグナル伝達の制御((増刊)Vol.30)2012
- Author(s)
  古川鋼一, 浜村和紀, 大川祐樹, 大海雄介, 古川圭子, 羊土社
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-23590371
[Book] シグナル伝達　研究最前線2012：糖鎖修飾によるシグナル伝達の制御2012
- Author(s)
  古川　鋼一
- Publisher
  羊土社、実験医学（増刊）Vol. 30
- Data Source
  KAKENHI-PROJECT-23590371
[Book] 糖鎖生物学第2版(監訳:鈴木康夫、木全弘治):14.シアル酸2010
- Author(s)
  古川鋼一
- Total Pages
  16
- Publisher
  コールドスプリングハーバー
- Data Source
  KAKENHI-PROJECT-20590319
[Book] 日本臨床(Drug discovery sciences in Japan with focus on molecular-targeted drugs 68)2010
- Author(s)
  Furukawa K, Hamamura K, Ohkawa Y, Furukawa K.
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-20590319
[Book] 糖鎖情報の独自性と普遍性蛋白質核酸酵素(2008年9月号増刊) : 癌細胞の形質を創出する細胞膜近傍の分子複合体2008
- Author(s)
  古川鋼一, その他
- Publisher
  共立出版(東京)
- Data Source
  KAKENHI-PROJECT-20590319
[Book] 蛋白質・核酸・酵素(Molecular complex in the vicinity of cell membrane generating cancer phenotypes 53)2008
- Author(s)
  Furukawa K, Hamamura K, Ohkawa Y, Nakashima H, Zhang Q, Furukawa K.
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-20590319
[Book] Knockout mice and glycolipids. In Comprehensive glycoscience. Article No. : 000862007
- Author(s)
  Furukawa, K. et al.
- Publisher
  Elsevier, Oxford, UK(in press)
- Data Source
  KAKENHI-PROJECT-16390075
[Book] 波及・深化する糖鎖研究:細菌毒素と糖脂質受容体:糖脂質による神経調節.実験医学(Vol.25-No.7, 115-120)2007
- Author(s)
  古川鋼一
- Total Pages
  6
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Book] Fukuda and U. Rutishauser2005
- Author(s)
  Koichi Furukawa
- Total Pages
  229
- Publisher
  Synthesis and function of glycosphingolipids. In Neuroglycobiology (Molecular and Cellular Neurobiology) eds by M.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390075
[Book] 糖鎖遺伝子研究 1.14 糖脂質糖鎖の合成に関与する転移酵素遺伝子、未来を拓く糖鎖科学2005
- Author(s)
  古川鋼一
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-16590243
[Book] Synthesis and function of glycosphingolipids. In Neuroglycobiology (Molecular and Cellular Neurobiology)(eds by M. Fukuda and U. Rutishauser)2005
- Author(s)
  Koichi Furukawa
- Total Pages
  229
- Publisher
  Oxford University Press, New York
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Novel molecular mechanisms for roles of gangliosides in the nervous system elucidated by genetic engineering2020
- Author(s)
  Furukawa, K., Ohmi, Y., Yesmin, F., Tajima, O., Kondo, Y., Pu Zhang, P., Hashimoto, N., Ohkawa, Y., Bhuiyan, R.H., Furukawa, K.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Pages: 1906-1906
- DOI
  10.3390/ijms21061906
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-19K07393, KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-17K19616
[Journal Article] Elucidation of the enigma of glycosphingolipids in the regulation of inflammation and degeneration — Great progress over the last 70 years —2019
- Author(s)
  Koichi Furukawa, Yuhsuke Ohmi, Yuji Kondo, Robiul H. Bhuiyan, Orie Tajima, Yuki Ohkawa, Keiko Furukawa
- Journal Title
  
  Proc. Jpn. Acad., Ser. B
  
  Volume: 95(3) Issue: 3 Pages: 136-149
- DOI
  10.2183/pjab.95.011
- NAID
  130007608536
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18K06925
[Journal Article] TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes2019
- Author(s)
  Takeuchi R, Kambe M, Miyata M, Jeyadevan U, Tajima O, Furukawa K, Furukawa K.
- Journal Title
  
  Sci. Rep.
  
  Volume: 9 Pages: 14740-14740
- DOI
  10.1038/s41598-019-51333-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-17K19616
[Journal Article] Loss of enzyme activity of mutated B4GALNT1 gene products found in patients with hereditary spastic paraplegia induces relatively mild neurological disorders: Similarity with phenotypes of B4galnt1 knockout mice2019
- Author(s)
  Robiul H. Bhuiyan, Yuhsuke Ohmi, Yuki Ohkawa, Pu Zhang, Maiko Takano, Noboru Hashimoto, Tetsuya Okajima, Keiko Furukawa, Koichi Furukawa
- Journal Title
  
  Neuroscienc
  
  Volume: 397 Pages: 94-106
- DOI
  10.1016/j.neuroscience.2018.11.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18H02628
[Journal Article] New era of research on cancer-associated glycosphingolipids2019
- Author(s)
  Koichi Furukawa, Yuhsuke Ohmi, Yuki Ohkawa, Robiul H. Bhuiyan, Pu Zhang, Orie Tajima, Noboru Hashimoto, Kazunori Hamamura, Keiko Furukawa
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 1544-1551
- DOI
  10.1111/cas.14005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-19K07393, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-18H02628
[Journal Article] Anti-GD2 CAR T cells could prove transformative for H3-K27M+ diffuse midline gliomas.2019
- Author(s)
  Koichi Furukawa, Yuhsuke Ohmi, Keiko Furukawa
- Journal Title
  
  Translational Cancer Research
  
  Volume: 8(2) Pages: 87-93
- DOI
  10.21037/tcr.2018.08.21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-18H02628
[Journal Article] Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging2019
- Author(s)
  Yo S, Hamamura K, Mishima Y, Hamajima K, Mori H, Furukawa K, Kondo H, Tanaka K, Sato T, Miyazawa K, Goto S, Togari A
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 10 Pages: 2825-2825
- DOI
  10.3390/ijms20112825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-17K11657, KAKENHI-PROJECT-17K19616
[Journal Article] The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid?binding lectin SIGLEC7 on the cell surface2019
- Author(s)
  Hashimoto N, Ito S, Tsuchida A, Bhuiyan RH, Okajima T, Yamamoto A, Furukawa K, Ohmi Y, Furukawa K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 294 Pages: 10833-10845
- DOI
  10.1074/jbc.ra118.007083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-19K07393, KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-17H04404, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-17K19616
[Journal Article] Cholera toxin B induces interleukine-1β production from resident peritoneal macrophages through pyrin as well as NLRP3 inflammasome.2019
- Author(s)
  Orimo, T., I. Sasaki, H. Hemmi, T. Ozasa, Y. Fukuda-Ohta, T. Ohta, M. Morinaka, M. Kitauchi, T. Yamaguchi, Y. Sato, T. Tanaka, K. Hoshino, K. I. Katayama, S. Fukuda, K. Miyake, M. Yamamoto, T. Satoh, K. Furukawa, E. Kuroda, K. J. Ishii, K. Takeda, and T. Kaisho.
- Journal Title
  
  Int Immunol
  
  Volume: 印刷中 Pages: 657-668
- DOI
  10.1093/intimm/dxz004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07071, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-18K16096, KAKENHI-PROJECT-19K23848, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17K19616
[Journal Article] Lactosylceramide synthase, encoded by β4-galactosylteransferase-5 and -6, is pivotal for neuronal generation and myelin formation in mice2018
- Author(s)
  Toru Yoshihara, Hiroyuki Satake, Toshikazu Nishie, Nozomu Okino, Toshihisa Hatta, Hiroki Otani, Hiroshi Suzuki, Kazushi Sugihara, Eikichi Kamimura, Noriyo Tokuda, Keiko Furukawa, Koichi Fururkawa, Makoto Ito, and Masahide Asano
- Journal Title
  
  Plos Genetics
  
  Volume: 14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02628
[Journal Article] Gangliosides in Inflammation and Neurodegeneration.2018
- Author(s)
  Furukawa K, Ohmi Y, Tajima O, Ohkawa Y, Kondo Y, Shuting J, Hashimoto N, Furukawa K.
- Journal Title
  
  Prog Mol Biol Transl Sci.
  
  Volume: 156 Pages: 265-287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06925
[Journal Article] Genome-wide CRISPR screens for Shiga toxins and Ricin reveal Golgi proteins critical for glycosylation2018
- Author(s)
  Songhai Tian, Khaja Muneeruddin, Mei Yuk Choi, Liang Tao, Robiul H. Bhuiyan, Yuhsuke Ohmi, Keiko Furukawa, Koichi Furukawa, Sebastian Boland, Scott A. Shaffer, Rosalyn M. Adams, Min Dong
- Journal Title
  
  PLoS Biol.
  
  Volume: 16(11) Pages: 1-31
- DOI
  10.1371/journal.pbio.2006951
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18H02628
[Journal Article] Gangliosides in inflammation and neurodegeneration2018
- Author(s)
  Furukawa K, Ohmi Y, Tajima O, Ohkawa Y, Kondo Y, Shuting J, Hashimoto N, Furukawa K
- Journal Title
  
  Prog. Mol. Biol. Transl. Sci.
  
  Volume: 156 Pages: 265-287
- DOI
  10.1016/bs.pmbts.2018.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18H02628
[Journal Article] Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking2018
- Author(s)
  Kondo, Y., Fu, J., Wang, H., Hoover, C., McDaniel, M., Steet, R., Patra, D., Song, J., Pollard, J., Cathey, S., Yago, T., Wiley, G., Macwana, S., Guthridge, J., McGee, S., Li, S., Griffin, C., Furukawa, K., James, J.A., Ruan, C., McEver, R.P., Wierenga, K., Gaffney, P., Xia, L.
- Journal Title
  
  J Clin Invest Insight
  
  Volume: 3
- DOI
  10.1172/jci.insight.121596
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02628
[Journal Article] ASCT2 defined by enzyme-mediated activation of radical sources enhances malignancy of GD2-plus small cell lung cancer2018
- Author(s)
  Nobutoshi Esaki, Yuki Ohkawa, Noboru Hashimoto, Yuhsuke Tsuda, Yuhsuke Ohmi, Robiul H. Bhuiyan, Norihiro Kotani, Koichi Honke, Atsushi Enomoto, Masahide Takahashi, Keiko Furukawa, Koichi Furukawa.
- Journal Title
  
  Cancer Scienc
  
  Volume: 109 Pages: 141-153
- DOI
  10.1111/cas.13448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-17K15720, KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-16K08591, KAKENHI-PROJECT-15H04696, KAKENHI-PROJECT-15K15080, KAKENHI-PROJECT-18H02628
[Journal Article] Inflammatory reactions in microenviron- ments, leading to melanomagenesis2018
- Author(s)
  Koichi Furukawa, Maiko Miyata, Mariko Kambe, Rika Takeuchi, Robiul H. Bhuiyan, Pu Zhang, Yuhsuke Ohmi, Keiko Furukawa
- Journal Title
  
  J. Clin. Cell. Immunol.
  
  Volume: 5:508 Pages: 1-3
- DOI
  10.4172/2155-9899.1000508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15H04696
[Journal Article] Roles of GalNAc-disialyl Lactotetraosyl Antigens in Renal Cancer Cells2018
- Author(s)
  Tsuchida A, Senda M, Ito A, Saito S, Kiso M, Ando T, Harduin-Lepers A, Matsuda A, Furukawa K, Furukawa K.
- Journal Title
  
  Sci. Rep.
  
  Volume: 8 Pages: 1-15
- DOI
  10.1038/s41598-018-25521-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-18H02628
[Journal Article] Enhancement of malignant properties of human glioma cells by ganglioside GD3/GD22018
- Author(s)
  Taiji Iwasawa, Pu Zhang, Yuki Ohkawa, Hiroyuki Momota, Toshihiko Wakabayashi, Yuhsuke Ohmi, Robiul H. Bhuiyan, Keiko Furukawa, Koichi Furukawa
- Journal Title
  
  Int J Oncol.
  
  Volume: 52 Pages: 1255-1266
- DOI
  10.3892/ijo.2018.4266
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-16K08731, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18H02628
[Journal Article] Differential roles of gangliosides in malignant properties of melanomas2018
- Author(s)
  Ohmi Y, Kambe M, Ohkawa Y, Hamamura K, Tajima O, Takeuchi R, Furukawa K, Furukawa K
- Journal Title
  
  PLOS One
  
  Volume: 13(11)
- DOI
  10.1371/journal.pone.0206881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18H02628
[Journal Article] Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice2018
- Author(s)
  Yoshihara T, Satake H, Nishie T, Okino N, Hatta T, Otani H, Suzuki H, Sugihara K, Kamimura E, Tokuda N, Furukawa K, Furukawa K, Ito M, Asano M.
- Journal Title
  
  PLOS Genetics
  
  Volume: 14 Pages: 1-24
- DOI
  10.1371/journal.pgen.1007545
- NAID
  120006502591
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-16H04681, KAKENHI-PROJECT-16H05364
[Journal Article] Differential roles of gangliosides in malignant properties of melanomas.2018
- Author(s)
  Ohmi Y, Kambe M, Ohkawa Y, Hamamura K, Tajima O, Takeuchi R, Furukawa K, Furukawa K.
- Journal Title
  
  PLoS One
  
  Volume: 13 Pages: 1-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06925
[Journal Article] Glycolipids: Essential regulator of neuro-inflammation, metabolism and gliomagenesis2017
- Author(s)
  Koichi Furukawa, Yuhsuke Ohmi, Shuting Ji, Pu Zhang, Robiul H. Bhuiyan, Yuki Ohkawa, Orie Tajima, Noboru Hashimoto, Keiko Furukawa
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1861 Pages: 2479-2484
- DOI
  10.1016/j.bbagen.2017.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-17K15720, KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15H04696, KAKENHI-PROJECT-15K15080
[Journal Article] Regulatory function of glycosphingolipids in the inflammation and degeneration2015
- Author(s)
  Furukawa K., Ohmi Y., Kondo Y., Ohkawa Y., Tajima O. and Furukawa K
- Journal Title
  
  Arch. Biochem. Biophys. 571, 58-65
  
  Volume: 571 Pages: 58-58
- DOI
  10.1016/j.abb.2015.02.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-26860321, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15K15080, KAKENHI-PROJECT-15K19073, KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-15H04696
[Journal Article] Ganglioside GD3 enhances invasiveness via Yes activation by forming a complex of GD3/PDGFRα/Yes in gliomas2015
- Author(s)
  Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Kotani N, Honke K, Suzumura A, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 16043-16058
- DOI
  10.1074/jbc.m114.635755
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15K19073, KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-24590478, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-26860321, KAKENHI-PROJECT-24390078
[Journal Article] b-series gangliosides crucially regulate leptin secretion in adipose tissues2015
- Author(s)
  Ji S., Ohkawa Y., Tokizane K., Ohmi Y., Banno R., Furukawa K., Kiyama H. and Furukawa K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 459 Pages: 189-195
- DOI
  10.1016/j.bbrc.2015.01.143
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15K19073, KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-26860321, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-15H04696
[Journal Article] Deficits in cognitive function and hippocampal plasticity in GM2/GD2 synthase knockout mice.2014
- Author(s)
  Sha S, Zhou L, Yin J, Takamiya K, Furukawa K, Furukawa K, Sokabe M, Chen L.
- Journal Title
  
  Hippocampus
  
  Volume: 24 Pages: 369-382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460404
[Journal Article] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor alpha and interleukin 6.2014
- Author(s)
  Miyata M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 445 Pages: 504-10
- DOI
  10.1016/j.bbrc.2014.02.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24790298, KAKENHI-PROJECT-24791182, KAKENHI-PROJECT-26870682
[Journal Article] Ganglioside GD3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas2014
- Author(s)
  Yuhsuke Ohmi, Yuki Ohkawa, et al.
- Journal Title
  
  J Neuroinflammation.
  
  Volume: 61(印刷中) Pages: 61-61
- DOI
  10.1186/1742-2094-11-61
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-23590371, KAKENHI-PUBLICLY-24111519, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24790298, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-26860321
[Journal Article] Glycosphingolipids in the regulation of the nervous system.2014
- Author(s)
  Furukawa K., Ohmi Y., Ohkawa Y., Tajima O. and Furukawa K.
- Journal Title
  
  Adv Neurobiol.
  
  Volume: 9 Pages: 307-307
- DOI
  10.1007/978-1-4939-1154-7_14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-26860321
[Journal Article] Ganglioside GD3 induces convergence and synergism of adhesion- and hepatocyte growth factor/Met-signals in melanomas.2014
- Author(s)
  Keiko Furukawa, Yuki Ohkawa, et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Pages: 52-63
- DOI
  10.1111/cas.12310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-24390078
[Journal Article] Trimeric Tn Antigen on Syndecan 1 Produced by ppGalNAc-T13 Enhances Cancer Metastasis via a Complex Formation with Integrin alpha5beta1 and Matrix Metalloproteinase 92013
- Author(s)
  Matsumoto Y, Zhang Q, Akita K, Nakada H, Hamamura K, Tsuchida A, Okajima T, Furukawa K, Urano T, Furukawa K
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 24264-24276
- DOI
  10.1074/jbc.m113.455006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-23590371, KAKENHI-PUBLICLY-24110507, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-25670141
[Journal Article] β4GalT6 is involved in the synthesis of lactosylceramide with less intensity thanβ4GalT5.2013
- Author(s)
  Tokuda N, Numata S, Li X, Nomura T, Takizawa M, Kondo Y, Yamashita Y, Hashimoto N, Kiyono T, Urano T, Furukawa K, Furukawa K
- Journal Title
  
  Glycobiology.
  
  Volume: 23 Pages: 1175-1183
- DOI
  10.1093/glycob/cwt054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23590394, KAKENHI-PROJECT-23659171, KAKENHI-PROJECT-25670141
[Journal Article] . TLR4#8211;MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide2013
- Author(s)
  Kondo, Y., Tokuda, N., Nishitani, C., Ohto, U., Akashi-TakKondo, Y., Tokuda, N., Nishitani, C., Ohto, U., Akashi-Takamura, S., Ito, Y., Uchikawa, M., Kuroki, Y., Miyake, K., Zhang, Q., Furukawa, K., Furukawa, K
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 110 Pages: 4714-4719
- DOI
  10.1073/pnas.1218508110
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23590564, KAKENHI-PROJECT-23659171, KAKENHI-PROJECT-23770106, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24619007, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-23121510
[Journal Article] Binding of a sialic acid-recognizing lectin Siglec-9 modulates adhesion dynamics of cancer cells via calpain-mediated protein degradation2013
- Author(s)
  Sabit I.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 35417-27
- DOI
  10.1074/jbc.m113.513192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23770164, KAKENHI-PROJECT-24390078
[Journal Article] Proteomic analysis of ganglioside-associated membrane molecules : Substantial basis for molecular clustering.2012
- Author(s)
  Hashimoto, N., Hamamura, K., Kotani, N., Furukawa, K., Kaneko, K., Honke, K., Furukawa, K.
- Journal Title
  
  Proteomics.
  
  Volume: 12 Pages: 3154-3163
- DOI
  10.1002/pmic.201200279
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23659171, KAKENHI-PROJECT-24390078
[Journal Article] Fine tuning of cell signals by glycosylation.2012
- Author(s)
  Furukawa K, Ohkawa Y, Yamauchi Y, Hamamura K, Ohmi Y, Furukawa K.
- Journal Title
  
  J Biochem
  
  Volume: 151 Pages: 573-578
- DOI
  10.1093/jb/mvs043
- NAID
  10031166098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361, KAKENHI-PUBLICLY-24111519
[Journal Article] Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD32012
- Author(s)
  Shibuya H.
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 1656-1664
- DOI
  10.1111/j.1349-7006.2012.02344.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590371
[Journal Article] Disialyl gangliosides enhance tumor phenotypes with differential modalities2012
- Author(s)
  Koichi Furukawa
- Journal Title
  
  Glycoconj J
  
  Volume: 29 Pages: 579-584
- DOI
  10.1007/s10719-012-9423-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361, KAKENHI-PUBLICLY-24111519
[Journal Article] Essential Roles of Gangliosides in the Formation and Maintenance of Membrane Microdomains in Brain Tissues2012
- Author(s)
  Yuhsuke Ohmi
- Journal Title
  
  Neurochem. Res
  
  Volume: 37 Pages: 1185-1191
- DOI
  10.1007/s11064-012-0764-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-22790280, KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361, KAKENHI-PUBLICLY-24111519
[Journal Article] Functional activation of Src family kinase yes protein is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD3.2011
- Author(s)
  Hamamura, K., Tsuji, M., Hotta, H., Ohkawa, Y., Takahashi, M., Shibuya, H., Nakashima, H., Yamauchi, Y., Hashimoto, N., Hattori, H., Ueda, M., Furukawa, K., Furukawa. K
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 18526-18537
- DOI
  10.1074/jbc.m110.164798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390076, KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361
[Journal Article] Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling: induction of the lipogenic pathway by a melanoma antigen.2011
- Author(s)
  Yamauchi Y, Furukawa K, Hamamura K, Furukawa K.
- Journal Title
  
  Cancer Res
  
  Volume: 71 Pages: 4989-4997
- DOI
  10.1158/0008-5472.can-10-4108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361
[Journal Article] Regulatory mechanisms of nervous systems with glycosphingolipids.2011
- Author(s)
  Furukawa K.
- Journal Title
  
  Neurochemical Research.
  
  Volume: 36 Pages: 1578-1586
- DOI
  10.1007/s11064-011-0494-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23659171
[Journal Article] Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling.2011
- Author(s)
  Ohkawa, Y., Ohmi, Y, Tajima, O., Yamauchi, Y, Furukawa, K., Furukawa' K
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 411 Pages: 483-489
- DOI
  10.1016/j.bbrc.2011.06.118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390076, KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371
[Journal Article] Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides.2011
- Author(s)
  Miyata M., Kambe M., Tajima O., Moriya S., Sawaki H., Hotta H., Kondo Y., Narimatsu H., Miyagi T., Furukawa K., Furukawa K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 2139-2149
- DOI
  10.1111/j.1349-7006.2011.02086.x
- NAID
  10030245717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590371
[Journal Article] Functional activation of Src family kinase Yes is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD3.2011
- Author(s)
  Hamamura K., Tsuji M., Hotta H., Ohkawa Y., Takahashi M., Shibuya H., Nakashima H., Yamauchi Y., Hashimoto N., Hattori H., Ueda M., Furukawa K.
- Journal Title
  
  J.Biol.Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains.2010
- Author(s)
  Ohkawa Y., Miyazaki S., Hamamura H., Ohmi Y., Yamauchi Y., Furukawa K.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 27213-27223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] GM1/GD1b/GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.2010
- Author(s)
  Dong Y., Ikeda K., Hamamura K., Zhang Q., Kondo Y., Matsumoto Y., Ohmi Y., Furukawa K., Taguchi R.
- Journal Title
  
  Cancer Sci 101
  
  Pages: 2039-2047
- NAID
  10027831670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice.2009
- Author(s)
  Greenshields K.N., Halstead S.K., Zitman F.M., Rinaldi S., Brennan K.M., O'Leary C., Chamberlain L.H., Easton A., Roxburgh J., Pediani J., Furukawa K., Goodyear C.S., Plomp J.J., Willison H.J.
- Journal Title
  
  J.Clin.Invest. 119
  
  Pages: 595-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Glycoconjugate glycosyltransferases.2009
- Author(s)
  Furukawa K., Tsuchida A., Okajima T.
- Journal Title
  
  Glycoconj. J. 26
  
  Pages: 987-998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Reduced motor and sensory functions and emotional response in GM3-only mice : emergence from early stage of life and exacerbation with aging.2009
- Author(s)
  Tajima O., Egashira N., Ohmi Y., Fukue Y., Mishima M., Iwasaki K., Fujiwara M., Sugiura Y., Furukawa K.
- Journal Title
  
  Behav Brain Res. 198
  
  Pages: 74-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues.2009
- Author(s)
  Ohmi Y., Tajima O., Ohkawa Y., Mori A., Sugiura Y., Furukawa K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 22405-22410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Molecules in the signaling pathway activated by gangliosides can be targets of therapeutics for malignant melanomas.2008
- Author(s)
  Furukawa K., Hamamura K., Nakashima H.
- Journal Title
  
  Proteomics 8
  
  Pages: 3312-3316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.2008
- Author(s)
  Hamamura K., Tsuji M., Nakashima H., Miyazaki S., Urano T., Yamamoto N., Ueda M., Furukawa K.
- Journal Title
  
  Biochim.Biophys.Acta 1780
  
  Pages: 513-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis212008
- Author(s)
  Furukawa, K.
- Journal Title
  
  J. Neurochem. 105
  
  Pages: 1057-1066
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Disruption of GM2/GD2 synthase gene resulted in neo-expressionof 9-O-acetyl GD3 irrespective of Tis21.2008
- Author(s)
  Furukawa, K., Aixinjueluo, W., et al.
- Journal Title
  
  J. Neurochem. 105
  
  Pages: 1057-1066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21.2008
- Author(s)
  Furukawa, K.
- Journal Title
  
  J. Neurochem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Disruption of GM2/GD2 synthase gene resulted in neo-expression of 9-O-acetyl GD3 irrespective of Tis21.2008
- Author(s)
  Furukawa K., Aixinjueluo W., Kasama T., Ohkawa Y., Yoshihara M., Ohmi Y., Tajima O., Suzumura A., Kittaka D.
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 1057-1066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.2008
- Author(s)
  Ohkawa Y., Miyazaki S., Miyata M., Hamamura K., Furukawa K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 373
  
  Pages: 14-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Journal Article] Disruption of GM2/GD2 synthase resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21.2008
- Author(s)
  Furukawa, K., et. al.
- Journal Title
  
  J. Neurochem. 105
  
  Pages: 1057-1066
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins2006
- Author(s)
  Okuda, T., Tokuda, N., Furukawa, K., et al.
- Journal Title
  
  J.Biol.Chem. (In press)
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Roles of glycolipids in the development and maintenance of nervous tissues.2006
- Author(s)
  Furukawa, K., et al.
- Journal Title
  
  Methods Enzymol 417
  
  Pages: 37-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Biosignals modulated by tumor-associated carbohydrate antigens: Novel targets for cancer therapy2006
- Author(s)
  Furukawa, K.
- Journal Title
  
  Ann. NY Acad. Sci. 1086
  
  Pages: 185-198
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Biosignals modulated by tumor-associated carbohydrate antigens : Novel targets for cancer therapy.2006
- Author(s)
  Furukawa, K., et. al.
- Journal Title
  
  Ann. NY Acad. Sci. 1086
  
  Pages: 185-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Roles of glycolipids in the development and maintenance of nervous tissues.2006
- Author(s)
  Furukawa, K. et al.
- Journal Title
  
  Methods Enzymol 417
  
  Pages: 37-52
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Roles of glycolipids in the development and maintenance of nervous tissues.2006
- Author(s)
  Furukawa, K., et. al.
- Journal Title
  
  Methods Enzymol. 417
  
  Pages: 37-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Roles of glycolipids in the development and maintenance of nervous tissues.2006
- Author(s)
  Furukawa, K.
- Journal Title
  
  Methods Enzymol. 417
  
  Pages: 37-52
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Roles of glycolipids in the development and maintenance ofnervous tissues.2006
- Author(s)
  Furukawa, K. et al.
- Journal Title
  
  Methods Enzymol 417
  
  Pages: 37-52
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Biosignals modulated by tumor-associated carbohydrate antigens : Novel targets for cancer therapy.2006
- Author(s)
  Furukawa, K.
- Journal Title
  
  Ann. NY Acad. Sci. 1086
  
  Pages: 185-198
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Complex Formation of Plk1 and INCENP Required for Metaphase-Anaphase Transition2006
- Author(s)
  Goto, H., Kiyono, T., Furukawa, K., et al.
- Journal Title
  
  Nature Cell Biology 8
  
  Pages: 180-187
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Roles of glycolipids in the development and maintenance of nervous tissues2006
- Author(s)
  Furukawa, K.
- Journal Title
  
  Methods Enzymol. 417
  
  Pages: 37-52
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590291
[Journal Article] Sensory nerve-dominant nerve degeneration and remodeling in the mutant mice lacking complex gangliosides2005
- Author(s)
  Sugiura, Y., Furukawa, K., et al.
- Journal Title
  
  Neuroscience 135
  
  Pages: 1167-1178
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells2005
- Author(s)
  Hamamura, K., Furukawa, K., et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 102
  
  Pages: 11041-11046
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Over-expression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody mediated injury in a model of acute motor axonal neuropathy2005
- Author(s)
  Goodfellow, J., Bowes, Tyrone, S., Furukawa, K., et al.
- Journal Title
  
  J.Neurosci. 25
  
  Pages: 1620-1628
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased response to formalin induced prolonged noxious stimulation2005
- Author(s)
  Handa, Y., Ozaki, N., Honda, T., Furukawa, K., et al.
- Journal Title
  
  Pain 117
  
  Pages: 271-279
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Glycosphingolipids in engineered mice : insights into function.2004
- Author(s)
  Furukawa, K.
- Journal Title
  
  Semin. Cell Dev. Biol 15
  
  Pages: 389-96
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590243
[Journal Article] Glycosphingolipids in engineered mice : insights into function.2004
- Author(s)
  Furukawa, Koichi.et al.
- Journal Title
  
  Semin.Cell Dev.Biol. 15
  
  Pages: 389-396
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Glycosphingolipids in engineered mice : insights into function.2004
- Author(s)
  Furukawa, K.
- Journal Title
  
  Semin.Cell Dev.Biol. 15
  
  Pages: 389-396
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590243
[Journal Article] Glycosphingolipids in engineered mice : insights into function.2004
- Author(s)
  Furukawa, Koichi. et al.
- Journal Title
  
  Semin.Cell Dev.Biol. 15
  
  Pages: 389-396
- Data Source
  KAKENHI-PROJECT-16590243
[Journal Article] Glycosphingolipids in engineered mice : insights into function.2004
- Author(s)
  Furukawa, K. et al.
- Journal Title
  
  Semin. Cell Dev. Biol. 15
  
  Pages: 389-396
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Glycosphingolipids in engineered mice : insights into function.2004
- Author(s)
  Furukawa, K., et al.
- Journal Title
  
  Semin. Cell Dev. Biol. 15
  
  Pages: 389-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390075
[Journal Article] Efficient generation of useful monoclonal antibodies reactive with globotriaosylceramide using knockout mice lacking Gb3/CD77 synthase.
- Author(s)
  Kondo Y., Tokuda N., Furukawa K., Ando R., Uchikawa M., Zhang Q., Fan X., Furukawa K.
- Journal Title
  
  Glycoconj. J. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590319
[Patent] GD2結合性分子2019
- Inventor(s)
  珠玖洋、赤堀泰、三輪啓志、藤原弘、古川鋼一、古川圭子、大海雄介
- Industrial Property Rights Holder
  三重大学、中部大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-142358
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K22518
[Patent] グロボ系糖脂質に対する効果的な抗体作成法2005
- Inventor(s)
  :古川鋼一、近藤裕史、安藤玲子、徳田典代、古川圭子
- Industrial Property Rights Holder
  国立大学法人名古屋大学、株式会社GPバイオサイエンス
- Filing Date
  2005-11-22
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Hydroxylation of ceramide modifies sensitivity of GD3-positive cancer cells to the killing of natural killer cells2019
- Author(s)
  Koichi Furukawa, Noboru Hashimoto, Akihito Yamamoto, Paul Crocker, Yusuke Ohmi, Robiul H. Bhuiyan, Keiko Furukawa
- Organizer
  International Symposium on Glycoconjugates (IGO GLYCO25)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Extracellular vesicles secreted from ganglioside GD3-expressing cancer cell lines contain high levels of integrins: Roles of lipid rafts2019
- Author(s)
  Koichi Furukawa, Iori Kobayashi, Yoshiki Kodama, Yuhsuke Ohmi, Satoko Yamamoto, Yuki Ohkawa, Mariko Kambe, Keiko Furukawa
- Organizer
  ISEV (International Society for Extracellular Vesicles)
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Targeting GD2 on cancer cells by an anti-GD2 antibody is promising in a variety of cancers: Challenge by CAR T2019
- Author(s)
  古川鋼一、赤堀泰、大海雄介、ファーハナイエスミン、浦野健、古川圭子、珠玖洋
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] 糖鎖とシグナル伝達 (Sugar chains and signal transduction)2019
- Author(s)
  古川鋼一
- Organizer
  第17回糖鎖科学コンソーシアムシンポジウム(JCGG) Symposium ~糖鎖研究と他領域との統合~
- Invited
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Roles of asialo-series ganglioside GD1alpha in human cancer cell lines2019
- Author(s)
  Robiul H. Bhuiyan、Farhana Yesmin、Yuji Kodo、Yuki Ohkawa、Yuhsuke Ohmi、Pu Zhang、Tetsuya Okajima、Keiko Furukawa、Koichi Furukawa
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] シアル酸結合レクチンSiglec7のガングリオシドGD3認識に対するセラミド構造の影響2019
- Author(s)
  橋本登、伊藤静香、土田明子、Roubiul H. Bhuiyan、岡島徹也、山本朗仁、古川圭子、大海雄介、古川鋼一
- Organizer
  第38回日本糖質学会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Roles of ganglioside GD3 in the regulation of microenvironment of Gliomas2019
- Author(s)
  Pu Zhang、Yuki Ohkawa、Robiul H. Bhuiyan、Hiroyuki Momota、Toshihiko Wakabayashi、Akira Kato、Yuhsuke Ohmi、Keiko Furukawa、 Tetsuya Okajima、Koichi Furukawa
- Organizer
  第38回日本糖質学会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] 大腸癌におけるGb3の機能解析2019
- Author(s)
  北沢裕昭、田中祥、藤井碧、大海雄介、大川祐樹、喬善楼、田島織絵、古川圭子、古川鋼一
- Organizer
  第38回日本糖質学会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] TNFa-and cAMP-signals oppositely regulate melanoma associated ganglioside GD3 synthase gene in human melanocytes2019
- Author(s)
  竹内理香、神戸真理子、宮田麻衣子、ウプルジャワデワン、田島織絵、古川鋼一、古川圭子
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Increased readthrough of premature termination codon of B4GALNT1 gene depending on cell cycle2019
- Author(s)
  Robiul H. Bhuiyan, Farhana Yesmin, Yuhsuke Ohmi, Yuki Ohkawa, Tetsuya Okajima, Keiko Furukawa, Koichi Furukawa
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Development of new CAR that suppress GD2 expressing tumors2019
- Author(s)
  赤堀泰、古川鋼一、藤原弘、美輪啓志、奥村悟司、王立楠、加藤琢磨、宮原慶裕、瀬尾尚宏、田中義正、珠玖洋
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Extracellular vesicles secreted from ganglioside GD3-expressing cancer cell lines contain high levels of integrins: Roles of lipid rafts.2019
- Author(s)
  Koichi Furukawa
- Organizer
  International Society for Extracellular Vesicles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06925
[Presentation] Unique function of ganglioside GD2 in malignant melanomas2019
- Author(s)
  Farhana Yesmin、Robiul H. Bhuiyan、Yuhsuke Ohmi、Tetsuya Okajima、Keiko Furukawa、Koichi Furukawa
- Organizer
  第38回日本糖質学会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Unique function of ganglioside GD2 in malignant melanomas2019
- Author(s)
  Farhana Yesmin、Robiul H. Bhuiyan、Yuhsuke Ohmi、Tetsuya Okajima、Keiko Furukawa、Koichi Furukawa
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Roles of ganglioside GD3 in the regulation of microenvironment of gliomas2019
- Author(s)
  Pu Zhang、Okiru Komine、Yuki Ohkawa、Yuhsuke Ohmi、Robiul H. Bhuiyan、Akira Kato、Keiko Furukawa、Tetsuya Okajima、Toshihiko Wakabayashi、Koichi Furukawa
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] マウスアストロサイト上に発現するガングリオシドの機能解析2019
- Author(s)
  大海雄介, 北浦洋子, 伊藤多佳子, 伴崚太, 古川圭子, 武田明, 河原敏男, 古川鋼一
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Regulation of cell signals by glycosphingolipids via cluster formation on the cell surface2019
- Author(s)
  Koichi Furukawa, Yuki Ohkawa, Kei Kaneko, Noboru Hashimoto, Zhang Pu, Robiul H. Bhuiyan, Yuhsuke Ohmi, Keiko Furukawa
- Organizer
  International Symposium on Bio-CHAINs from Single Molecules to Highly Organized Systems. co-organized by G-CHAIN and CREST exosome project
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22518
[Presentation] Targeting GD2 on cancer cells by an anti-GD2 antibody is promising in a variety of cancers: Challenge by CAR T.2019
- Author(s)
  古川鋼一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06925
[Presentation] Roles of asialo-series ganglioside GD1alpha in human cancer cell lines2018
- Author(s)
  Robiul H.Bhuiyan, Yuji Kondo, Yuki Ohkawa, Yuhsuke Ohmi, Pu Zhand, Tetsuya Okajima, Keiko Furukawa, Koichi Furukawa
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] グリオーマーの微小環境調節におけるガングリオシドGD3の役割2018
- Author(s)
  張璞, 大川祐樹, 大海雄介, Robiul H.Bhuiyan, 加藤彰, 古川圭子, 岡島徹也, 若林俊彦, 古川鋼一
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] 糖鎖改変に伴う肝脂肪蓄積抑制の分子メカニズム2018
- Author(s)
  田島織絵, 古川圭子, 古川鋼一
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] 癌関連ガングリオシド合成酵素遺伝子の発現制御機構シグナルの解析：シグナル伝達阻害剤による検討2018
- Author(s)
  竹内理香, 宮田麻衣子, ウプルジャヤデワン, 田島織絵, 神戸真理子, 古川鋼一, 古川圭子
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] 糖鎖リモデリング癌細胞由来エキソソームの膜分子組成と分泌機構の解析2018
- Author(s)
  小林伊織, 大海雄介, 古川圭子, ブイヤンロビウル, 張璞, 古川鋼一
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] 癌関連スフィンゴ糖脂質による細胞動態の分別的制御に関するタイムラプス解析2018
- Author(s)
  古川圭子, 神戸真理子, 大海雄介, 大川祐樹, 竹内理香, 田島織絵, 安藤弘宗, 古川鋼一
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] 癌転移におけるエクソソームの役割の解析2018
- Author(s)
  児玉佳輝, 章青, 大海雄介, Hasan Bhuiyan Robiul, Yesmin Farhana, 山本聡子, 古川圭子, 古川鋼一
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] 癌関連スフィンゴ糖脂質による細胞動態の分別的制御に関するタイムラプス解析2018
- Author(s)
  古川　圭子
- Organizer
  第91回日本生化学大会
- Data Source
  KAKENHI-PROJECT-18K06925
[Presentation] Ig上のシアル酸機能の解析とSALSA法によるマウス脳組織のシアル化糖鎖構造解析2018
- Author(s)
  大海雄介, 古川鋼一
- Organizer
  第37回　日本糖質学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02628
[Presentation] メラノサイトとメラノーマでは癌関連糖鎖合成酵素遺伝子の発現制御メカニズムが異なる2017
- Author(s)
  竹内理香、宮田麻衣子、ウプルジャヤデワン、田島織絵、神戸真理子、古川鋼一、古川圭子
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 癌関連スフィンゴ糖脂質による細胞動態の制御：蛍光標識糖脂質によるタイムラプス解析2017
- Author(s)
  古川圭子、神戸真理子、大川祐樹、大海雄介、竹内理香、田島織絵、安藤弘宗、古川鋼一
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] シグナル伝達阻害剤を用いた糖鎖合成酵素遺伝子の分別的発現調節機構の解明2017
- Author(s)
  竹内理香、宮田麻衣子、ウプルジャヤデワン、田島織絵、神戸真理子、古川鋼一、古川圭子
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] Differential regulation of cell phenotypes by tumor associated glycosphingolipids2017
- Author(s)
  Keiko Furukawa, Mariko Kambe, Yuki Ohkawa, Yuhsuke Ohmi, Rika Takeuchi, Orie Tajima, Koichi Furukawa
- Organizer
  24th International Symposium on Glycoconjugates
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] ガングリオシドGD3/GD2はヒト由来神経膠腫U251細胞の悪性形質を増強する2017
- Author(s)
  張　璞、岩沢太司、大川裕樹、RH Bhuiyan、百田洋之、若林俊彦、大海雄介、岡島徹也、古川圭子、古川鋼一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] グリア細胞上の脂質ラフトにおけるガングリオシドの役割2017
- Author(s)
  大海雄介、大川祐樹、張僕、小林伊織、小谷典弘、本家孝一、古川圭子、河原敏男、古川鋼一
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] Roles of asialo-series ganglioside GD1alpha in human cancer cell lines2017
- Author(s)
  Robiul H. Bhuiyan, Yuji Kondo, Yuki Ohkawa, Yuhsuke Ohmi, Pu Zhang, Tetsuya Okajima,Keiko Furukawa, Koichi Furukawa
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] ガングリオシドGD2 は中性アミノ酸トランスポーターASCT2と協調的に働き小細胞肺がんの悪性形質を亢進させる2017
- Author(s)
  江崎寛季、大川祐樹、橋本登、津田祐介、大海祐介、ブイヤロビウル、古谷典弘、本家孝一、榎本篤、高橋雅英、古川圭子、古川鋼一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 糖鎖改変マウスにおける肝脂肪蓄積抑制の分子メカニズム2017
- Author(s)
  田島織絵、古川圭子、古川鋼一
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 癌関連スフィンゴ糖脂質糖鎖による細胞形質の制御2016
- Author(s)
  古川圭子
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] ガングリオシドGD3の発現はグリオーマの発生・進展を促進する2015
- Author(s)
  大川祐樹、百田洋之、加藤　彰、橋本　登、津田裕介、江崎寛季、古川圭子、大海雄介、夏目敦至、若林利彦、古川鋼一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] ヒトmelanoma細胞におけるNeogenin細胞内ドメイン(NeICD)標的遺伝子の同定2015
- Author(s)
  金子　慶、大川祐樹、橋本　登、大海雄介、山内祥生、岡島徹也、小谷典弘、本家孝一、古川圭子、古川鋼一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] メラノサイトにおける炎症性サイトカイン及びcAMPによる癌関連GD3合成酵素遺伝子の発現抑制2015
- Author(s)
  古川圭子、竹内理香、田島織絵、神戸真理子、宮田麻衣子、古川鋼一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 高脂肪食負荷に対する糖鎖変異マウスの応答2015
- Author(s)
  田島織絵、古川鋼一、古川圭子
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] TLC-LESA-QTRAP6500によるSiglec-7特異的認識gangliosideGD3の構造解析2015
- Author(s)
  橋本　登、伊藤静香、池田和貴、土田明子、Paul R. Crocker、古川圭子、田口　良、古川鋼一
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 癌関連糖鎖との協同作用により癌形質を発現する分子群の同定と作用機構2015
- Author(s)
  古川鋼一、大川祐樹、橋本　登、金子　慶、小谷典弘、本家孝一、大海雄介、古川圭子
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 肺がん細胞特異的に発現する酸性糖脂質抗原GD2と協調的な分子の同定と機能解析2015
- Author(s)
  江崎寛季、大川祐樹、橋本　登、津田裕介、津田裕介、金子　慶、大海雄介、小谷典弘、本家孝一、古川圭子、古川鋼一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 糖脂質糖鎖によるシグナル制御のメカニズム2015
- Author(s)
  古川鋼一、大川祐樹、大海雄介、橋本　登、古川圭子
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 皮膚微小環境におけるメラノサイトの糖鎖合成酵素遺伝子の発現調節2015
- Author(s)
  竹内理香、宮田麻衣子、田島織絵、神戸真理子、古川鋼一、古川圭子
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] NK細胞上Siglec-7を介したシアル酸含有O型糖鎖による癌免疫監視からの逃避機構2015
- Author(s)
  橋本　登、土田明子、高野舞子、古川圭子、古川鋼一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 複合糖質と糖鎖認識分子との相互作用の時空間的ダイナミクス2013
- Author(s)
  古川　鋼一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] TNFα及び紫外線によるメラノサイトとメラノーマのGD3合成酵素遺伝子の発現誘導2013
- Author(s)
  古川　圭子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] 複合糖質と糖鎖認識分子との相互作用の時空間的ダイナミクス2013
- Author(s)
  古川鋼一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] TNFα及び紫外線によるメラノサイトとメラノーマのGD3合成酵素遺伝子の発現誘導2013
- Author(s)
  古川圭子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] GD3発現細胞での接着とHGF刺激によるAktの相乗的活性化とアポトーシス抑制2012
- Author(s)
  古川圭子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] GD3発現細胞での接着とHGF刺激によるAktの相乗的活性化とアポトーシス抑制2012
- Author(s)
  古川圭子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] Convergence and enhancement of the growth and adhesion signals by ganglioside GD3in human melanomas2011
- Author(s)
  Furukawa Keiko
- Organizer
  21st International Symposium on Glycoconjugates
- Place of Presentation
  Austria
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] メラノーマ特異的酸性スフィンゴ糖脂質によるc-Met機能の増強メカニズム2011
- Author(s)
  古川圭子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] メラノーマ特異的酸性スフィンゴ糖脂質によるc-Met機能の増強メカニズム.2011
- Author(s)
  古川圭子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] Convergence and enhancement of the growth and adhesion signals by ganglioside GD3 in human melanomas.2011
- Author(s)
  Furukawa K.
- Organizer
  21st International Symposium on Glycoconjugates
- Place of Presentation
  ウィーン大学、Austria
- Data Source
  KAKENHI-PROJECT-23590371
[Presentation] Disruption of GM2/GD2 synthase gene resulted in over expression of 9-O-acetyl GD3 irrespective of Tis212010
- Author(s)
  Furukawa K., Aixinjueluo W., Kasama T., Ohmi Y., Ohkawa Y., Tajima O., Suzumura A., Kittaka.D.
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] メラノーマにおいてガングリオシドGD3はFAKの強い活性化を脂質ラフトで誘導する2010
- Author(s)
  大川裕樹、宮崎清香、神戸真理子、宮田麻衣子、橋本登、浜村和紀、古川圭子、古川鋼一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21.2010
- Author(s)
  Furukawa K., Aixinjueluo W., T. Kasama Y. Ohkawa M. Yoshihara Y. Ohmi O. Tajima A. Suzumura D.Kittaka, K.Furukawa
- Organizer
  4th ISN Special Neurochemistry Conference
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒト口腔扁平上皮癌におけるマーカーとしてのtype2HとLewisY抗原2010
- Author(s)
  堀田公司、浜村和紀、豊國伸哉、渋谷英伸、徳田典代、古川圭子、山本憲幸、服部宇、上田実、古川鋼一
- Organizer
  第69回日本癌学会学術総
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] メラノーマ細胞のガングリオシドGD3による細胞増殖と接着シグナルの収斂と増強効果2010
- Author(s)
  古川圭子
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル(大阪)
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマにおけるSrcファミリーキナーゼYesのガングリオシドGD3依存的活性化機構2010
- Author(s)
  浜村和紀、辻桃子、堀田宏司、中島英行、橋本登、古川圭子、古川鋼一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] 糖鎖変異マウスにおける成長障害の分子メカニズム2010
- Author(s)
  田島織絵、藤田雄輝、大川裕樹、大海雄介、古川圭子、古川鋼一
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] GM3 only miceの脊髄における神経変性機構の解明2010
- Author(s)
  大海雄介、田島織絵、大川裕樹、古川圭子、古川鋼一
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] GM1合成酵素の発現はメラノーマ細胞株のガングリオシド修飾により腫瘍形成を抑制する2010
- Author(s)
  董宇、池田和貴、浜村和紀、章青、近藤裕史、松本康之、大海雄介、山内祥生、古川圭子、田口良、古川鋼一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] メラノーマ細胞のガングリオシドGD3による細胞増殖と接着シグナルの収斂と増強効果2010
- Author(s)
  古川圭子、大川祐樹、神戸真理子、宮田麻衣子、章青、山森達也、高橋智絵、田島織絵、浜村和紀、古川鋼一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Proteomic gangliosides-containing microdomains in malignant melanomas.2010
- Author(s)
  Hashimoto N., Hamamura K., Ohmi Y., Ohkawa Y., Inagaki K., Furukawa K.
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Lysosomal accumulation of disease-associated gangliosides and small molecules that stimulate their lysosome-to-plasma membrane transport in Niemamm-Pick type C cells.2010
- Author(s)
  Yamauchi Y., Yoshida K., Chang T., Furukawa K.
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] GM3 onlyマウスの中枢神経系におけるCCN5/Wisp2遺伝子の機能解析2010
- Author(s)
  大川裕樹、大海雄介、田島織絵、稲垣邦江、徳田典代、古川圭子、古川鋼一
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒト口腔扁平上皮癌におけるtype 2HとLewis Y抗原の発現2009
- Author(s)
  堀田宏司、浜村和紀、豊國伸哉、徳田典代、古川圭子、服部宇、上田実、古川鋼一
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Role of SREBP pathway in Akt signaling in human melanoma cells.2009
- Author(s)
  Yamauchi Y., Furukawa K.
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマ細胞においてSREBP経路はAktシグナルによって制御されている2009
- Author(s)
  山内祥生、古川圭子、古川鋼一
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] GM1/GD1b/GA1合成酵素発現によるSK-MEL-37メラノーマ細胞の腫瘍形質減弱の分子メカニズム2009
- Author(s)
  浜村和紀、董宇、池田和貴、章青、近藤裕史、松本康之、大海雄介、古川圭子、田口良、古川鋼一
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] GM3 onlyマウスの神経変性における補体の役割2009
- Author(s)
  大海雄介、田島織絵、大川祐樹、古川圭子、古川鋼一
- Organizer
  第29回日本糖質学会
- Place of Presentation
  高山
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] スフィンゴ糖脂質による脂質ラフトの制御とその破綻2009
- Author(s)
  古川鋼一、大海雄介、浜村和紀、古川圭子
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Adhesion of melanoma calls is enhanced by GD3 via recruitment of integrins to lipid rafts.2009
- Author(s)
  Ohkawa Y., Miyazaki S., Hamamura K., Yamauchi Y., Furukawa K.
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] 糖鎖欠損マウスにおける進行性神経機能障害の基盤としてのアセチルコリン受容体異常2009
- Author(s)
  田島織絵、江頭伸昭、大海雄介、福江善彦、三島健一、岩崎克典、藤原道弘、杉浦康夫、古川圭子、古川鋼一
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマ細胞における膜型シアリダーゼ(NEU3)の癌性形質への関与2009
- Author(s)
  古川圭子
- Organizer
  第68回日本癌学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] 細胞膜ミクロドメインの健常性維持と機能における酸性糖脂質の役割2009
- Author(s)
  古川鋼一、大海雄介、田島織絵、大川祐樹、徳田典代、古川圭子
- Organizer
  第29回日本糖質学会
- Place of Presentation
  高山
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマ細胞における膜型シアリダーゼ(NEU3)の癌性形質への関与2009
- Author(s)
  古川圭子、田島織絵、神戸真理子、宮田麻衣子、古川鋼一、宮城妙子
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマにおける酸性糖脂質GD2の役割2009
- Author(s)
  大海雄介、大川祐樹、近藤裕史、浜村和紀、古川圭子、古川鋼一
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマの悪性形質におけるガングリオシドの役割2009
- Author(s)
  大海雄介、大川祐樹、近藤裕史、橋本登、濱村和紀、古川圭子、古川鋼一
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] GD3発現メラノーマ細胞においてインテグリンが脂質ラフトでクラスター構造を形成する2009
- Author(s)
  大川祐樹、宮崎清香、浜村和紀、宮田麻衣子、大海雄介、橋本登、田島織絵、古川圭子、古川鋼一
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Molecular complex formation containing glycolipids for the regulation of signals.2008
- Author(s)
  Furukawa K., Ohmi Y., Ohkawa Y., Kondo Y., Zhang Q., Furukwawa K.
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマ細胞におけるシアリダーゼNeu3の癌性形質への関与2008
- Author(s)
  古川圭子、田島織絵、神戸真理子、宮田麻衣子、宮城妙子、古川鋼一
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Ganglioside GD3-dependent Akt signaling leads to activation of SREBP to regulate lipogenesis in melanoma cells.2008
- Author(s)
  Yamauchi Y., Watanabe Y., Miyazaki S., Furukawa K.
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] ヒトメラノーマ細胞におけるシアリダーゼNeu3の癌性形質への関与。2008
- Author(s)
  古川圭子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] 癌転移に関与する糖転移酵素の同定とその糖鎖産物の作用機構2008
- Author(s)
  松本康之、章青、徳田典代、土田明子、古川圭子、浦野健、古川鋼一
- Organizer
  第28回日本糖質学会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] A small interfering RNA targeting adaptor molecules, p130Cas and paxillin as novel therapeutics for human melanomas.2008
- Author(s)
  Makino Y., Hamamura K., Nakashima H., Furukawa K.
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] 脂質ラフト構築におけるガングリオシドの役割2008
- Author(s)
  大海雄介、田島織絵、大川裕樹、森敦史、稲垣邦江、古川圭子、古川鋼一
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590319
[Presentation] Roles of Src family kinases in the malignant properties of melanomas enhanced by ganglioside GD32007
- Author(s)
  Furukawa, K.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Effects of over-expression of Neu3 in human melanoma cells.2007
- Author(s)
  Furukawa, K., et. al.
- Organizer
  80th Annual Meeting of Biochemistry and 30th Annual Meeting of Molecular Biology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Mechanisms for the enhancement of malignant signals with ganglioside GD3 in human melanoma cells2007
- Author(s)
  Furukawa, F.
- Organizer
  14th European Carbohydrate Symposium
- Place of Presentation
  Germany
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Roles of Src family kinases in the malignant properties of melanomas enhanced by ganglioside GD3.2007
- Author(s)
  Furukawa, K., et. al.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Mechanisms for the enhancement of malignant signals with ganglioside GD3 in human melanoma cells.2007
- Author(s)
  Furukawa, F., et. al.
- Organizer
  14th European Carbohydrate Symposium
- Place of Presentation
  Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Involvement of integrins in the malignant phenotypes enhanced by ganglioside GD3 expression in human melanoma cells2007
- Author(s)
  Furukawa K.
- Organizer
  Glycobiology and Sphingobiology 2007(GS2007)-Hakomori Commemorative Forum
- Place of Presentation
  徳島
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] ヒトメラノーマにおけるNeu3過剰発現の効果2007
- Author(s)
  古川圭子
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Involvement of integrins in the malignant phenotypes enhanced by ganglioside GD3 expression in human melanoma cells.2007
- Author(s)
  Furukawa K., et. al.
- Organizer
  Glycobiology and Sphingobiology 2007(G52007)-Hakomori Commemorative Forum
- Place of Presentation
  Tokushima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Roles of Src family kinases in the malignant properties of melanomas enhanced by ganglioside GD32007
- Author(s)
  Furukawa, K.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Interaction of GD3 with functional molecules in the vicinity of the cell membrane, leading to the malignant phenotypes of human melanomas.2006
- Author(s)
  Furukawa K., et. al.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] Interaction of GD3 with functional molecules in the vicinity of the cell membrane,leading to the malignant phenotypes of human melanomas2006
- Author(s)
  Furukawa K.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590291
[Presentation] ガングリシドによるAPP切断とその切断断片による酸化ストレス応答の制御
- Author(s)
  山口世堯, 山内祥生, 松本康之, 橋本登, 大海雄介, 近藤裕史, 古川圭子, 古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor alpha and interleukin 6
- Author(s)
  Keiko Furukawa, Maiko Miyata, Masatoshi Ichihara, Orie Tajima, Sayaka Sobue, Mariko Kambe, Kazumitsu Sugiura, and Koichi Furukawa
- Organizer
  9th International Symposium on Glycosyltransferase
- Place of Presentation
  Porto, Portugal
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] ヒトメラノーマ細胞由来exosomeに含まれるガングリオシドGD3の解析
- Author(s)
  瀬尾庸一郎、大川祐樹、古川圭子、古川鋼一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] 脂肪細胞のレプチン分泌と中枢神経系による脂質代謝制御におけるb系列ガングリオシドの調節機能
- Author(s)
  姫　朱亭、大海雄介、大川祐樹、古川圭子、古川鋼一
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学豊田講堂（愛知県・名古屋市）
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] UVB照射ケラチノサイトは炎症性サイトカインを分泌してメタノサイトにおける癌関連GD3合成酵素遺伝子の発現を誘導する
- Author(s)
  古川圭子、宮田麻衣子、田島織絵、神戸真理子、市原正智、祖父江沙矢加、古川鋼一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] Siglec-7とガングリオシドGD3の結合における分子認識の構造特異性
- Author(s)
  橋本登、伊藤静香、水野顕智、池田和貴、土田明子、Paul R. Crocker、古川圭子、田口良、古川鋼一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] レプチン分泌と脂質代謝におけるb系列ガングリオシドの調節機能
- Author(s)
  姫　朱亭、大海雄介、大川祐樹、古川圭子、古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] スフィンゴ糖脂質機能の統合的理解
- Author(s)
  古川鋼一、橋本　登、大川祐樹、大海雄介、金子　慶、古川圭子
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学豊田講堂（愛知県・名古屋市）
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] UBV照射ケラチノサイトが分泌する炎症性サイトカインがメラノサイトにおける癌関連ガングリオシド糖鎖の糖鎖合成酵素遺伝子を発現誘導する
- Author(s)
  竹内理香、宮田麻衣子、田島織絵、神戸真理子、古川鋼一、古川圭子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460404
[Presentation] GD3発現メラノーマにおけるNeogeninの悪性形質創出メカニズム
- Author(s)
  金子慶, 大川祐樹, 橋本登, 大海雄介, 小川光貴, 山内祥生, 小谷典弘, 本家孝一, 古川圭子, 古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460404

1. FURUKAWA Koichi (80211530)

# of Collaborated Projects: 21 results

# of Collaborated Products: 114 results
2. URANO Takeshi (70293701)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 沼田真一郎 (20311714)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 大海雄介 (10584758)

# of Collaborated Projects: 3 results

# of Collaborated Products: 67 results
5. TAJIMA Orie (10362237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
6. SUZUKI Kenichi (50423059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ITOH Michi-ichiro (70223188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HONDA Takashi (20165608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 菊地浩吉 (00045345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松浦晃洋 (70157238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 益子高 (30157200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 別宮好文 (70199454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 笠原正典 (30241318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中島邦夫 (40022800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田中実 (90024736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAKEUCHI Rika

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
17. OHKAWA Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 29 results
18. ZHANG Pu

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. Bhuiyan POBIUL H.

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. ESAKI Nobutoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. HASHIMOTO Noboru

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
22. KANEKO Kei

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. SEO Yoichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. YAMAUCHI Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
25. SOBUE Sayaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. OKAJIMA Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. ENOMOTO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. MOMOTA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
29. KATO Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. OHTO Umeharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. YAMAJI Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. KONDO Hisataka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. HAMAMURA Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. YOSHIHARA Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. Sugihara Kazushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 宮田麻衣子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 山下依子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 本家孝一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 若林俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 夏目敦至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 田口良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 戸苅彰史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 山本朗仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 邊見弘明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 改正恒康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 佐々木泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 福田有里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 成瀬智恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 浅野雅秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 八田稔久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FURUKAWA Keiko 古川 圭子

Research Projects

Research Products

Co-Researchers

Dynamics of microenvironmental regulation by extracellular vesicles with carbohydrates and molecular cluster formationOngoing

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Regulatory mechanisms for signals on cell membrane and under microenvironment by complex of glycosphingolipids and membrane moleculesOngoing

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癌関連スフィンゴ糖脂質と膜分子間の相互作用の時空間的動態と癌性形質増強機構の解析Principal InvestigatorOngoing

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Regulatory mechanisms for inflammatory responses and expression of cancer-associated glycosyltransferase genes by microenvironment factors, and their implicationsPrincipal Investigator

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Spatio-temporal analysis of cell membrane molecules involved in the enhancement of malignant properties by glycosphingolipidsPrincipal Investigator

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The molecular mechanisms of the convergence in the early stage of the cell growth and adhesion signalings enhanced by glycosphingolipidsPrincipal Investigator

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Roles of glycosphinglipids in converging process of the cell signals of proliferation and adhesion in cancer cells.Principal Investigator

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The mechanisms for the neuronal degeneration in the retina of the mutant mice lacking b-series acidic glycosphingolipids.Principal Investigator

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スフィンゴ糖脂質によるraftの構造調節と増殖・分化シグナルの制御機構Principal Investigator

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Analysis of the mechanism for neuronal degeneration and regeneration and responsible gene using the mutant mice disrupted of complex gangliosidePrincipal Investigator

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癌特異的糖転移酵素遺伝子を標的とする癌治療法の開発Principal Investigator

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FURUKAWA Keiko 古川圭子