MATSUSAKA Keisuke 松坂恵介

Researcher Number	40610150
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 千葉大学, 大学院医学研究院, 准教授 2019 – 2022: 千葉大学, 医学部附属病院, 准教授 2017 – 2018: 千葉大学, 大学院医学研究院, 講師 2016: 千葉大学, 大学院医学研究院, 助教 2015: 千葉大学, 医学研究院, 助教 2013 – 2015: 千葉大学, 医学(系)研究科(研究院), 助教 2012: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Experimental pathology / Human pathology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Digestive surgery / Human pathology
Keywords	Principal Investigator 胃癌 / エピジェネティクス / Epstein-Barr virus / エピゲノム異常 / マイクロサテライト不安定性 / TP53 / 早期細胞老化 / DNAメチル化 / 子宮体癌 / 大腸癌 … More / DNAメチル化形質 / EBV陽性胃癌 / ゲノム異常 / 胃癌の分子基盤 / 遺伝子変異 / EBV / ウイルス / 病理学 / ウイルス学 … More Except Principal Investigator SNADET / エピゲノム / 胃癌細胞株 / 上皮間葉転換 / miR200 / RRM2 / 転写因子 / STAT3 / DNMT1 / エクソソーム / 幹細胞 / マイクロRNA / トランスジェニックマウス / SP細胞 / LMP2A / エピジェネティクス / 胃癌 / EBウイルス / EBウイルス関連胃癌 Less

野生型p53を保持するMSI胃癌の発癌機構の解明とその治療戦略の確立Principal Investigator
- Principal Investigator
  
  松坂恵介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Chiba University
社会実装可能な人工知能による画期的十二指腸腫瘍risk層別内視鏡診断システムの開発
- Principal Investigator
  
  沖元謙一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Chiba University
臓器横断的な孤発性MSI陽性腫瘍の本態解明と治療戦略の構築Principal Investigator
- Principal Investigator
  
  松坂恵介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Chiba University
Clarification of genome/epigenome interaction in microsatellite instable gastric cancerPrincipal Investigator
- Principal Investigator
  
  Matsusaka Keisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Chiba University
Identification of factors contributing to epigenetic alteration and maintenance in EBV infection.Principal Investigator
- Principal Investigator
  
  Matsusaka Keisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chiba University
Clarification of mechanism in induction of DNA methylation using Epstein-Barr virus infection experimentPrincipal Investigator
- Principal Investigator
  
  Matsusaka Keisuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Chiba University
Analysis on alterated chromatin status of viral genome in the host cells.
- Principal Investigator
  
  Kaneda Atsushi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Comprehensive DNA methylation analysis in the close interaction between Epstein-Barr virus and host cellPrincipal Investigator
- Principal Investigator
  
  MATSUSAKA Keisuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Chiba University
  The University of Tokyo
EB virus-associated gastric carcinoma. Molecular mechanisms of DNA hypermethylation and strategy for gastric cancer therapy.
- Principal Investigator
  
  FUKAYAMA Masashi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human pathology
- Research Institution
  The University of Tokyo

[Book] 胃と腸 58(10)2023
- Author(s)
  沖元謙一郎, 松村倫明, 松坂恵介, 加藤順, 加藤直也
- Total Pages
  238
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22K06936
[Book] DNA and Histone Methylation as Cancer Targets2017
- Author(s)
  Matsusaka K, Kaneda A.
- Total Pages
  624
- Publisher
  Springer
- ISBN
  9783319597867
- Data Source
  KAKENHI-PROJECT-16K08729
[Book] 病理と臨床2016
- Author(s)
  松坂恵介、宇於崎宏
- Total Pages
  4
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-16K08729
[Book] 成人病と生活習慣病2013
- Author(s)
  松坂恵介, 深山正久
- Total Pages
  140
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-24790347
[Book] 成人病と生活習慣病2013
- Author(s)
  松坂恵介,深山正久
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-24790347
[Book] 感染症と, 病理からのメッセージ, EBVと胃癌, 病理と臨床2013
- Author(s)
  阿部浩幸,松坂恵介,深山正久
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24790347
[Journal Article] Utility of prophylactic clipping after colorectal cold snare polypectomy in patients on oral antithrombotic agents2024
- Author(s)
  Akizue Naoki, Okimoto Kenichiro, Matsumura Tomoaki, Matsusaka Keisuke, Inaba Yosuke, Horio Ryosuke, Takahashi Satsuki, Goto Chihiro, Kurosugi Akane, Sonoda Michiko, Kaneko Tatsuya, Ohta Yuki, Taida Takashi, Kato Jun, Ikeda Jun-ichiro, Kato Naoya
- Journal Title
  
  Gastrointestinal Endoscopy
  
  Volume: 99 Issue: 5 Pages: 826-829.e3
- DOI
  10.1016/j.gie.2024.01.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] Severe ulcerative colitis induced by COVID-19 vaccination2024
- Author(s)
  Taida Takashi, Kato Jun, Ishikawa Kentaro, Akizue Naoki, Ohta Yuki, Okimoto Kenichiro, Saito Keiko, Matsusaka Keisuke, Matsumura Tomoaki, Kato Naoya
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: Online ahead of print. Issue: 3 Pages: 447-450
- DOI
  10.1007/s12328-024-01926-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] Differences in mucosal permeability among patients with ulcerative colitis classified based on the colonic location and disease activity2024
- Author(s)
  Shiratori Wataru, Ohta Yuki, Matsusaka Keisuke, Ohyama Yuhei, Mamiya Yukiyo, et al.
- Journal Title
  
  Clinical and Translational Gastroenterology
  
  Volume: Online ahead of print. Issue: 5 Pages: e00692-e00692
- DOI
  10.14309/ctg.0000000000000692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] Association of frequent hypermethylation with high grade histological subtype in lung adenocarcinoma2023
- Author(s)
  Ito Yuki、Usui Genki、Seki Motoaki、Fukuyo Masaki、Matsusaka Keisuke、Hoshii Takayuki、Sata Yuki、Morimoto Junichi、Hata Atsushi、Nakajima Takahiro、Rahmutulla Bahityar、Kaiho Taisuke、Inage Terunaga、Tanaka Kazuhisa、Sakairi Yuichi、Suzuki Hidemi、Yoshino Ichiro、Kaneda Atsushi
- Journal Title
  
  Cancer Science
  
  Volume: Online Issue: 7 Pages: 3003-3013
- DOI
  10.1111/cas.15817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08880, KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-21K07934, KAKENHI-PROJECT-22K19553
[Journal Article] A case of metallosis mimicking cutaneous malignant melanoma following total elbow arthroplasty2023
- Author(s)
  Arima Mio, Matsuzawa Takamitsu, Hashimoto Eiko, Ochiai Nobuyasu, Matsusaka Keisuke, Inozume Takashi
- Journal Title
  
  JEADV Clinical Practice
  
  Volume: 2 Issue: 2 Pages: 343-346
- DOI
  10.1002/jvc2.131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K08374
[Journal Article] Endoscopic submucosal dissection for early gastric cancer, using a disposable endoscope2023
- Author(s)
  Okimoto Kenichiro, Matsumura Tomoaki, Fujie Mai, Akizue Naoki, Matsusaka Keisuke, Kato Jun, Kato Naoya
- Journal Title
  
  Endoscopy
  
  Volume: 55 Issue: S 01 Pages: E881-E882
- DOI
  10.1055/a-2109-0778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] Validity of pathological diagnosis for early colorectal cancer in genetic background2023
- Author(s)
  Okimoto Kenichiro、Hirotsu Yosuke、Arai Makoto、Amemiya Kenji、Akizue Naoki、Ohta Yuki、Taida Takashi、Saito Keiko、Ohyama Hiroshi、Matsumura Tomoaki、Nishimura Motoi、Matsushita Kazuyuki、Matsusaka Keisuke、・・Kato Naoya、Omata Masao
- Journal Title
  
  Cancer Medicine
  
  Volume: - Issue: 7 Pages: 8490-8498
- DOI
  10.1002/cam4.5596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-20H03668, KAKENHI-PROJECT-19KT0019, KAKENHI-PROJECT-20K07336, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-23K27646
[Journal Article] Gel immersion endoscopic mucosal resection for pedunculated Brunner’s gland hyperplasia in the duodenal bulb near the pylorus2023
- Author(s)
  Goto Chihiro, Okimoto Kenichiro, Matsumura Tomoaki, Akizue Naoki, Matsusaka Keisuke, Kato Jun, Kato Naoya
- Journal Title
  
  Endoscopy
  
  Volume: 55 Issue: S 01 Pages: E985-E986
- DOI
  10.1055/a-2139-4068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] Diagnostic Value of Adding Magnifying Chromoendoscopy to Magnifying Narrow-Band Imaging Endoscopy for Colorectal Polyps2023
- Author(s)
  Matsumura Tomoaki、Ebigbo Alanna、・・Matsusaka Keisuke、Nagashima Kengo、Maehata Tadateru、Yahagi Naohisa、Messmann Helmut、Kato Naoya
- Journal Title
  
  Clinical Gastroenterology and Hepatology
  
  Volume: - Issue: 10 Pages: 2551-2559.e2
- DOI
  10.1016/j.cgh.2023.01.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] The neuroendocrine carcinoma component of gastric mixed adenoneuroendocrine carcinoma could develop with MLH1 deficiency independent of TP53 mutation2023
- Author(s)
  Hashimoto R, Matsusaka K, Matsumura T, Hayano K, Kato N, Matsubara H, Ikeda JI.
- Journal Title
  
  Pathol Int.
  
  Volume: - Issue: 6 Pages: 261-263
- DOI
  10.1111/pin.13324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-21K06881
[Journal Article] Tumor localization by Prostate Imaging and Reporting and Data System (PI-RADS) version 2.1 predicts prognosis of prostate cancer after radical prostatectomy2023
- Author(s)
  Fujimoto Ayumi, Sakamoto Shinichi, Horikoshi Takuro, Zhao Xue, Yamada Yasutaka, Rii Junryo, Takeuchi Nobuyoshi, Imamura Yusuke, Sazuka Tomokazu, Matsusaka Keisuke, Ikeda Jun-ichiro, Ichikawa Tomohiko
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-36685-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-21K06881
[Journal Article] Outcomes for Underwater Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection of 21?30-mm Colorectal Polyps: A Feasible Study2023
- Author(s)
  Okimoto Kenichiro, Matsumura Tomoaki, Matsusaka Keisuke, Inaba Yosuke, Ishikawa Tsubasa, Akizue Naoki, Kaneko Tatsuya, Ota Masayuki, Ohta Yuki, Taida Takashi, Saito Keiko, Ogasawara Sadahisa, Maruoka Daisuke, Kato Jun, Ikeda Jun-ichiro, Kato Naoya
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 68 Issue: 10 Pages: 3963-3973
- DOI
  10.1007/s10620-023-08093-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K15403
[Journal Article] Long-Term Course of Gastric Submucosal Tumors: Growth Speed and Size-Increasing Factors2023
- Author(s)
  Shiratori Wataru、Matsumura Tomoaki、Okimoto Kenichiro、Akizue Naoki、Matsusaka Keisuke、・・Kato Jun、Ikeda Jun-ichiro、Kato Naoya
- Journal Title
  
  Gastrointestinal Endoscopy
  
  Volume: - Issue: 6 Pages: 1052-1058.e2
- DOI
  10.1016/j.gie.2023.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-21K06881
[Journal Article] Anti-proliferating and apoptosis-inducing activity of chemical compound FTI-6D in association with p53 in human cancer cell lines2023
- Author(s)
  Inoue Takato、Matsuda Kazuaki、Matsusaka Keisuke、Nakajima Masaya、Takeno Yukari、Miyazaki Toko、Shintaku Takahiko、Yoda Natsumi、Saito Takahiko、Ikeda Eriko、Mano Yasunobu、Shinohara Kenichi、Rahmutulla Bahityar、Fukuyo Masaki、Kita Kazuko、Nemoto Tetsuhiro、Kaneda Atsushi
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 369 Pages: 110257-110257
- DOI
  10.1016/j.cbi.2022.110257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K07164
[Journal Article] Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric neoplasia using the longitudinally monitored cohorts2023
- Author(s)
  Usui Genki, Matsusaka Keisuke, Huang Kie Kyon, Zhu Feng, Shinozaki Tomohiro, et al.
- Journal Title
  
  eBioMedicine
  
  Volume: 98 Pages: 104844-104844
- DOI
  10.1016/j.ebiom.2023.104844
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-21K07934, KAKENHI-PROJECT-22K19553
[Journal Article] Clinical utility of artificial intelligence assistance in histopathologic review of lymph node metastasis for gastric adenocarcinoma2023
- Author(s)
  Matsushima Jun, Sato Tamotsu, Yoshimura Yuichiro, Mizutani Hiroyuki, Koto Shinichiro, Matsusaka Keisuke, Ikeda Jun-ichiro, Sato Taiki, Fujii Akiko, Ono Yuko, Mitsui Takashi, Ban Shinichi, Matsubara Hisahiro, Hayashi Hideki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 28 Issue: 8 Pages: 1033-1042
- DOI
  10.1007/s10147-023-02356-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] Adenocarcinoma of the stomach and esophagogastric junction with low DNA methylation show poor prognoses2022
- Author(s)
  Urabe Masayuki、Matsusaka Keisuke、Ushiku Tetsuo、Fukuyo Masaki、Rahmutulla Bahityar、Yamashita Hiroharu、Seto Yasuyuki、Fukayama Masashi、Kaneda Atsushi
- Journal Title
  
  Gastric Cancer
  
  Volume: 26 Issue: 1 Pages: 95-107
- DOI
  10.1007/s10120-022-01344-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-22K19553
[Journal Article] Association of tumors having <scp>Epstein?Barr</scp> virus in surrounding lymphocytes with poor prognosis2022
- Author(s)
  Yogi Norikazu、Usui Genki、Matsusaka Keisuke、Fukuyo Masaki、Fujiki Ryoji、Seki Motoaki、Takano Shigetsugu、Abe Hiroyuki、Morikawa Teppei、Ushiku Tetsuo、Ohtsuka Masayuki、Kaneda Atsushi
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 2 Pages: 1122-1136
- DOI
  10.1002/cam4.4967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07934, KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K07164
[Journal Article] Why is endosonography insufficient for residual diagnosis after neoadjuvant therapy for esophageal cancer? Solutions using muscle layer evaluation2022
- Author(s)
  Yonemoto Shohei、Uesato Masaya、Nakano Akira、Murakami Kentaro、Toyozumi Takeshi、Maruyama Tetsuro、Suito Hiroshi、Tamachi Tomohide、Kato Manami、Kainuma Shunsuke、Matsusaka Keisuke、Matsubara Hisahiro
- Journal Title
  
  World Journal of Gastrointestinal Endoscopy
  
  Volume: 14 Issue: 5 Pages: 320-334
- DOI
  10.4253/wjge.v14.i5.320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-20H03749
[Journal Article] Repression of DERL3 via DNA methylation by Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma2022
- Author(s)
  Kondo S, Okabe A, Nakagawa T, Matsusaka K, Fukuyo M, Rahmutulla B, Dochi H, Mizokami H, Kitagawa Y, Kurokawa T, Mima M, Endo K, Sugimoto H, Wakisaka N, Misawa K, Yoshizaki T, Kaneda A.
- Journal Title
  
  Biochimica et Biophysica Acta - Molecular Basis of Disease
  
  Volume: 1869(2) Issue: 2 Pages: 166598-166598
- DOI
  10.1016/j.bbadis.2022.166598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09689, KAKENHI-PROJECT-21K09627, KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-20K21648, KAKENHI-PROJECT-22K19553, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-23K21477, KAKENHI-PROJECT-23K23859
[Journal Article] Long-term vonoprazan administration causes gastric fundic gland-type hyperplastic polyps and chronic bleeding2022
- Author(s)
  Goto Chihiro、Okimoto Kenichiro、Matsusaka Keisuke、Matsumura Tomoaki、Akizue Naoki、Ohta Yuki、Taida Takashi、Saito Keiko、Kato Jun、Kato Naoya
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 16 Issue: 2 Pages: 159-163
- DOI
  10.1007/s12328-022-01751-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06936
[Journal Article] The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-22021
- Author(s)
  Maimaiti Maihulan、Sakamoto Shinichi、Sugiura Masahiro、Kanesaka Manato、Fujimoto Ayumi、Matsusaka Keisuke、Xu Minhui、Ando Keisuke、Saito Shinpei、Wakai Ken、Imamura Yusuke、Nakayama Keiichi、Kanai Yoshikatsu、Kaneda Atsushi、Ikehara Yuzuru、Ikeda Jun-Ichiro、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11478-11478
- DOI
  10.1038/s41598-021-90748-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K09572, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-21K20742
[Journal Article] Identification of clonal immunoglobulin λ light-chain gene rearrangements in AL amyloidosis using next-generation sequencing2021
- Author(s)
  Kimura K、Tsukamoto S、Miyazaki K、Kawajiri-Manako C、Ishii A、Rahmutulla B、Fukuyo M、Oshima-Hasegawa N、Mitsukawa S、Takeda Y、Mimura N、Takeuchi M、Ohwada C、Iseki T、Matsusaka K、Sanada M、Yokote K、Kaneda A、Ishida T、Suzuki K、Nakaseko C、Sakaida E
- Journal Title
  
  Experimental Hematology
  
  Volume: 101-102 Pages: 34-41
- DOI
  10.1016/j.exphem.2021.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K08831, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-20K08723
[Journal Article] Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein‐Barr virus‐positive gastric cancer2021
- Author(s)
  Li Wenzhe、Okabe Atsushi、Usui Genki、Fukuyo Masaki、Matsusaka Keisuke、Rahmutulla Bahityar、Mano Yasunobu、Hoshii Takayuki、Funata Sayaka、Hiura Nobuhiro、Fukayama Masashi、Tan Patrick、Ushiku Tetsuo、Kaneda Atsushi
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 8 Pages: 3349-3362
- DOI
  10.1111/cas.14978
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-19H03690
[Journal Article] Solid serous neoplasm of the pancreas with locally aggressive behaviors2021
- Author(s)
  Kouchi Yusuke、Yamashita Kazushi、Harada Sakurako、Shinomiya Yoshiki、Mishima Takashi、Takano Shigetsugu、Matsusaka Keisuke、Nasu Katsuhiro、Ikeda Jun‐ichiro、Ohtsuka Masayuki、Kishimoto Takashi
- Journal Title
  
  Pathology International
  
  Volume: 71 Issue: 11 Pages: 795-797
- DOI
  10.1111/pin.13163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K09190, KAKENHI-PROJECT-21K06881
[Journal Article] Collision of Epstein?Barr virus-positive and -negative gastric cancer, diagnosed by molecular analysis: a case report2021
- Author(s)
  Miyabe Ken、Saito Motonobu、Koyama Kei、Umakoshi Michinobu、Ito Yukinobu、Yoshida Makoto、Kudo-Asabe Yukitsugu、Saito Katsuharu、Nanjo Hiroshi、Maeda Daichi、Matsusaka Keisuke、Goto Akiteru、Kono Koji
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 21 Issue: 1 Pages: 97-97
- DOI
  10.1186/s12876-021-01683-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07454, KAKENHI-PROJECT-18K08652, KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-21K08675, KAKENHI-PROJECT-20K17948
[Journal Article] Genetic profiles of Barrett’s esophagus and esophageal adenocarcinoma in Japanese patients2021
- Author(s)
  Tokunaga Mamoru、Okimoto Kenichiro、Akizue Naoki、Ishikawa Kentaro、Hirotsu Yosuke、Amemiya Kenji、Ota Masayuki、Matsusaka Keisuke、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 17671-17671
- DOI
  10.1038/s41598-021-97249-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K17451, KAKENHI-PROJECT-20H03668, KAKENHI-PROJECT-20K08276, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-21K07956, KAKENHI-PROJECT-18K07408, KAKENHI-PROJECT-23K21402
[Journal Article] Genetic alterations in squamous cell lung cancer associated with idiopathic pulmonary fibrosis2021
- Author(s)
  Hata Atsushi、Nakajima Takahiro、Matsusaka Keisuke、Fukuyo Masaki、Nakayama Manabu、Morimoto Junichi、Ito Yuki、Yamamoto Takayoshi、Sakairi Yuichi、Rahmutulla Bahityar、Ota Satoshi、Wada Hironobu、Suzuki Hidemi、Iwata Takekazu、Matsubara Hisahiro、Ohara Osamu、Yoshino Ichiro、Kaneda Atsushi
- Journal Title
  
  International Journal of Cancer
  
  Volume: - Issue: 12 Pages: 3008-3018
- DOI
  10.1002/ijc.33499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-21K08880
[Journal Article] Stratification of HPV-associated and HPV-negative oropharyngeal squamous cell carcinomas based on DNA methylation epigenotypes.2020
- Author(s)
  Nakagawa T, Matsusaka K, Misawa K, Ota S, Fukuyo M, Rahmutulla B, Kunii N, Sakurai D, Hanazawa T, Matsubara H, Okamoto Y, Kaneda A
- Journal Title
  
  Int J Cancer.
  
  Volume: 146 Issue: 9 Pages: 2460-2474
- DOI
  10.1002/ijc.32890
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03726
[Journal Article] High expression of CXCL14 is a biomarker of lung adenocarcinoma with micropapillary pattern2020
- Author(s)
  Sata Yuki, Nakajima Takahiro, Fukuyo Masaki, Matsusaka Keisuke, Hata Atsushi, Morimoto Junichi, Rahmutulla Bahityar, Ito Yuki, Suzuki Hidemi, Yoshino Ichiro, Kaneda Atsushi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 7 Pages: 2588-2597
- DOI
  10.1111/cas.14456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03726
[Journal Article] Epstein-Barr virus-positive gastric cancer involves enhancer activation through activating transcription factor 3.2020
- Author(s)
  Asakawa Y, Okabe A, Fukuyo M, Li W, Ikeda E, Mano Y, Funata S, Namba H, Fujii T, Kita K, Matsusaka K, Kaneda A.
- Journal Title
  
  Cancer Sci.
  
  Volume: －
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457
[Journal Article] Cross-species chromatin interactions drive transcriptional rewiring in Epstein-Barr virus-positive gastric adenocarcinoma2020
- Author(s)
  Okabe Atsushi, Huang Kie Kyon, Matsusaka Keisuke, Fukuyo Masaki, Xing Manjie, Ong Xuewen, Hoshii Takayuki, Usui Genki, Seki Motoaki, Mano Yasunobu, Rahmutulla Bahityar, Kanda Teru, Suzuki Takayoshi, Rha Sun Young, Ushiku Tetsuo, Fukayama Masashi, Tan Patrick, Kaneda Atsushi
- Journal Title
  
  Nature Genetics
  
  Volume: 52 Issue: 9 Pages: 919-930
- DOI
  10.1038/s41588-020-0665-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K09184, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03690, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-18J00861, KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-19K22399, KAKENHI-PROJECT-19K16101
[Journal Article] Epstein‐Barr virus positive gastric cancer involves enhancer activation through ATF32020
- Author(s)
  Asakawa Yuta、Okabe Atsushi、Fukuyo Masaki、Li Wenzhe、Ikeda Eriko、Mano Yasunobu、Funata Sayaka、Namba Hiroe、Fujii Takahiro、Kita Kazuko、Matsusaka Keisuke、Kaneda Atsushi
- Journal Title
  
  Cancer Science
  
  Volume: 00 Issue: 5 Pages: 1-11
- DOI
  10.1111/cas.14370
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-18J00861, KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-19K16101
[Journal Article] Establishment of epigenetic markers to predict irradiation efficacy against oropharyngeal cancer.2020
- Author(s)
  Kurokawa T, Nakagawa T, Matsusaka K, Fukuyo M, Mima M, Misawa K, Rahmutulla B, Ikeda JI, Hanazawa T, Okamoto Y, Kaneda A
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 4 Pages: 1407-1416
- DOI
  10.1111/cas.14338
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-19K18722
[Journal Article] Thirty years of Epstein-Barr virus-associated gastric carcinoma.2020
- Author(s)
  Fukayama M, Abe H, Kunita A, Shinozaki-Ushiku A, Matsusaka K, Ushiku T, Kaneda A.
- Journal Title
  
  Virchows Arch
  
  Volume: 476 Issue: 3 Pages: 353-365
- DOI
  10.1007/s00428-019-02724-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-17K15611
[Journal Article] A low DNA methylation epigenotype in lung squamous cell carcinoma and its association with idiopathic pulmonary fibrosis and poorer prognosis.2020
- Author(s)
  Hata A, Nakajima T, Matsusaka K, Fukuyo M, Morimoto J, Yamamoto T, Sakairi Y, Rahmutulla B, Ota S, Wada H, Suzuki H, Matsubara H, Yoshino I, Kaneda A.
- Journal Title
  
  Int J Cancer
  
  Volume: 146 Issue: 2 Pages: 388-399
- DOI
  10.1002/ijc.32532
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-17K10774
[Journal Article] The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis.2018
- Author(s)
  Takane K, Fukuyo M, Matsusaka K, Ota S, Rahmutulla B, Matsushita K, Miyauchi H, Nakatani Y, Matsubara H, Kaneda A.
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 66 Pages: 32653-32666
- DOI
  10.18632/oncotarget.25987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09004, KAKENHI-PROJECT-17K16530, KAKENHI-PROJECT-16H05412, KAKENHI-PROJECT-16K08729
[Journal Article] Synergistic Cytotoxic Effect on Gastric Cancer Cells of an Immunotoxin Cocktail in Which Antibodies Recognize Different Epitopes on CDH172018
- Author(s)
  Kusano-Arai O, Iwanari H, Kudo S, Akiba H, Matsusaka K, Kaneda A, Fukayama M, Tsumoto K, Hamakubo T.
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 37 Issue: 1 Pages: 1-11
- DOI
  10.1089/mab.2017.0043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-16H05412
[Journal Article] Epstein-Barr virus infection induces genome-wide de novo DNA methylation in non-neoplastic gastric epithelial cells.2017
- Author(s)
  Matsusaka K, Funata S, Fukuyo M, Seto Y, Aburatani H, Fukayama M, Kaneda A.
- Journal Title
  
  Journal of Pathology
  
  Volume: 242 Issue: 4 Pages: 391-399
- DOI
  10.1002/path.4909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-16H05412, KAKENHI-PROJECT-17H04666
[Journal Article] Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus.2017
- Author(s)
  Okabe A, Funata S, Matsusaka K, Namba H, Fukuyo M, Rahmutulla B, Oshima M, Iwama A, Fukayama M, Kaneda A.
- Journal Title
  
  Scientific reports
  
  Volume: 7 Issue: 1 Pages: 7924-7924
- DOI
  10.1038/s41598-017-08370-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-16H05412, KAKENHI-PROJECT-17H06564
[Journal Article] Frequent promoter hypermethylation associated with human papillomavirus infection in pharyngeal cancer.2017
- Author(s)
  Nakagawa T, Matsusaka K, Misawa K, Ota S, Takane K, Fukuyo M, Rahmutulla B, Shinohara K, Kunii N, Sakurai D, Hanazawa T, Matsubara H, Nakatani Y, Okamoto Y, Kaneda A.
- Journal Title
  
  Cancer Letters
  
  Volume: 407 Pages: 21-31
- DOI
  10.1016/j.canlet.2017.08.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-17K01959, KAKENHI-PROJECT-17K11376, KAKENHI-PROJECT-17K16530
[Journal Article] A. Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection.2017
- Author(s)
  Funata S, Matsusaka K, Yamanaka R, Yamamoto S, Okabe A, Fukuyo M, Aburatani H, Fukayama M, Kaneda A.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 33 Pages: 55265-55279
- DOI
  10.18632/oncotarget.19423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-16H05412
[Journal Article] Coupling CDH17 and CLDN18 markers for comprehensive membrane-targeted detection of human gastric cancer.2016
- Author(s)
  Matsusaka K, Ushiku T, Urabe M, Fukuyo M, Abe H, Ishikawa S, Seto Y, Aburatani H, Hamakubo T, Kaneda A, Fukayama M.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 51 Pages: 64168-64181
- DOI
  10.18632/oncotarget.11510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-16H05412, KAKENHI-PROJECT-15H06098, KAKENHI-PROJECT-15K08611, KAKENHI-PROJECT-16K08729
[Journal Article] Coupling CDH17 and CLDN18 markers for comprehensive membrane-targeted detection of human gastric cancer.2016
- Author(s)
  K. Matsusaka, T. Ushiku, M. Urabe, M. Fukuyo, H. Abe, S. Ishikawa, Y. Seto, H. Aburatani, T. Hamakubo, A. Kaneda, M. Fukayama
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 39 Pages: 64168-64181
- DOI
  10.18632/oncotarget.11638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-16H05412, KAKENHI-PROJECT-16K08729
[Journal Article] Tumor Content Chart-Assisted HER2/CEP17 Digital PCR Analysis of Gastric Cancer Biopsy Specimens.2016
- Author(s)
  Matsusaka K, Ishikawa S, Nakayama A, Ushiku T, Nishimoto A, Urabe M, Kaneko N, Kunita A, Kaneda A, Aburatani H, Fujishiro M, Seto Y, Fukayama M.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 4 Pages: e0154430-e0154430
- DOI
  10.1371/journal.pone.0154430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-16H05412, KAKENHI-PROJECT-16K15422, KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-15H04806
[Journal Article] Genetic and epigenetic aberrations occurring in colorectal tumors associated with serrated pathway.2016
- Author(s)
  Sakai E, Fukuyo M, Ohata K, Matsusaka K, Doi N, Mano Y, Takane K, Abe H, Yagi K, Matsuhashi N, Fukushima J, Fukayama M, Akagi K, Aburatani H, Nakajima A, Kaneda A.
- Journal Title
  
  Int J Cancer
  
  Volume: 138 Issue: 7 Pages: 1634-44
- DOI
  10.1002/ijc.29903
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15H06098, KAKENHI-PROJECT-26670595, KAKENHI-PROJECT-26860257, KAKENHI-PROJECT-16H05412
[Journal Article] TET2 functions as a resistance factor against DNA methylation acquisition during Epstein-Barr virus infection.2016
- Author(s)
  Namba-Fukuyo H, Funata S, Matsusaka K, Fukuyo M, Rahmutulla B, Mano Y, Fukayama M, Aburatani H, Kaneda A
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 49 Pages: 81512-81526
- DOI
  10.18632/oncotarget.13130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-16H05412, KAKENHI-PROJECT-15J06475, KAKENHI-PROJECT-16K08729
[Journal Article] Pulmonary Metastasis of Combined Hepatocellular and Cholangiocarcinoma: A Unique Radiographic Presentation with Air-space Consolidation Masquerading as Pneumonia and Primary Pulmonary Adenocarcinoma2015
- Author(s)
  3.Ishii T, Goto Y, Matsuzaki H, Ohishi N, Sakamoto Y, Saito R, Matsusaka K, Shibahara J, Nagase T.
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 11 Pages: 1389-1392
- DOI
  10.2169/internalmedicine.54.3375
- NAID
  130005072929
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860257
[Journal Article] Evaluation of 18F-FDG uptake for detecting lymph node metastasis of gastric cancer: a prospective pilot study for one-to-one comparison of radiation dose and pathological findings.2015
- Author(s)
  Okumura Y, Aikou S, Onoyama H, Jinbo K, Yamagata Y, Mori K, Yamashita H, Nomura S, Takahashi M, Koyama K, Momose T, Abe H, Matsusaka K, Ushiku T, Fukayama M, Seto Y.
- Journal Title
  
  World J Surg Oncol.
  
  Volume: 13 Issue: 1 Pages: 327-327
- DOI
  10.1186/s12957-015-0743-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-26860257
[Journal Article] DNA methylation in gastric cancer, related to Helicobacter pylori and Epstein-Barr virus2014
- Author(s)
  Keisuke Matsusaka, Sayaka Funata, Masashi Fukayama and Atsushi Kaneda.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 20(14) Issue: 14 Pages: 3916-3926
- DOI
  10.3748/wjg.v20.i14.3916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790347, KAKENHI-PROJECT-26670595, KAKENHI-PROJECT-26860257
[Journal Article] DNA methylation accumulation and its predetermination of future cancer phenotypes.2014
- Author(s)
  Kaneda A, Matsusaka K, Sakai E, Funata S.
- Journal Title
  
  J Biochem
  
  Volume: 156 Issue: 2 Pages: 63-72
- DOI
  10.1093/jb/mvu038
- NAID
  40020155022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670595
[Journal Article] Methylation epigenotypes and genetic features in colorectal laterally spreading tumors2014
- Author(s)
  Sakai E, Ohata K, Chiba H, Matsuhashi N, Doi N, Fukushima J, Endo H, Takahashi H, Tsuji S, Yagi K, Matsusaka K, Aburatani H, Nakajima A, Kaneda A.
- Journal Title
  
  Int J Cancer
  
  Volume: in press Issue: 7 Pages: 1586-95
- DOI
  10.1002/ijc.28814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790713, KAKENHI-PROJECT-26670595, KAKENHI-PROJECT-26860257, KAKENHI-PROJECT-26860517
[Journal Article] An indeterminate result of QuantiFERON-TB Gold In-Tube for miliary tuberculosis due to a high level of IFN-γ production2014
- Author(s)
  Sho Hangai, Akihide Yoshimi, Atsuko Hosoi, Keisuke Matsusaka, Motoshi Ichikawa, Masashi Fukayama, Mineo Kurokawa
- Journal Title
  
  International Journal of Hematology
  
  Volume: 99 Issue: 4 Pages: 523-526
- DOI
  10.1007/s12185-014-1504-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860257
[Journal Article] 胃癌におけるゲノム網羅的な解析から何が明らかになったか2014
- Author(s)
  松坂恵介、金田篤志
- Journal Title
  
  分子消化器病
  
  Volume: 11 Pages: 113-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670595
[Journal Article] Epstein-Barr virusinfection as an epigenetic driver of tumorigenesis2012
- Author(s)
  Kaneda A, Matsusaka K, Aburatani H, Fukayama M
- Journal Title
  
  Cancer Research
  
  Volume: Vol.72 Issue: 14 Pages: 3445-3450
- DOI
  10.1158/0008-5472.can-11-3919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249022, KAKENHI-PROJECT-22390255, KAKENHI-PROJECT-24221011
[Journal Article] 炎症と発癌Epstein-Barr virus関連胃癌2011
- Author(s)
  松坂恵介, 深山正久
- Journal Title
  
  BIO Clinica
  
  Volume: 26 Pages: 893-898
- Data Source
  KAKENHI-PROJECT-20249022
[Journal Article] Classification of Epstein-Barr virus positive gastric cancers by definition of DNA methylation Epigenotypes2011
- Author(s)
  Matsusaka K, Fukayama M, et al.
- Journal Title
  
  Cancer Research
  
  Volume: 71 Pages: 7187-7197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249022
[Presentation] Identification of genetic/epigenetic alterations based on wild-type TP53 in high methylation gastric cancer.2018
- Author(s)
  Keisuke Matsusaka, Yasunobu Mano, Masaki Fukuyo, Masayuki Urabe, Rahmutulla Bahityar, Eriko Ikeda, Kazuko Kita, Hiroyuki Abe, Tetsuhiro Nemoto, Yasuyuki Seto, Masashi Fukayama, Atsushi Kaneda.
- Organizer
  The 77th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-16K08729
[Presentation] 高メチル化胃癌におけるTP53変異非依存性ゲノム・エピゲノム異常の相乗効果．2018
- Author(s)
  松坂恵介、眞野恭伸、福世真樹、松田和暁、井上貴登、浦辺雅之、バハテヤリ・ラヒムトラ、池田英里子、阿部浩幸、喜多和子、瀬戸泰之、根本哲宏、深山正久、金田篤志．
- Organizer
  第29回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-16K08729
[Presentation] 胃癌におけるTP53変異とは独立したゲノム・エピゲノム相互作用の同定2018
- Author(s)
  松坂恵介, 眞野恭伸, 福世真樹, 浦辺雅之, 喜多和子, 根本哲宏, バハテヤリ・ラムヒトラ, 瀬戸泰之, 深山正久, 金田篤志.
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K08729
[Presentation] Identification of unique genetic/epigenetic alteration in gastric cancer with high DNA methylation.2017
- Author(s)
  松坂恵介, 眞野恭伸、福世真樹、浦辺雅之、バハテヤリ・ラムヒトラ、油谷浩幸、瀬戸泰之、深山正久、金田篤志
- Organizer
  第106回日本病理学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08729
[Presentation] メチル化胃癌における特異的なゲノム・エピゲノム変異の同定2017
- Author(s)
  松坂恵介、眞野恭伸、福世真樹、浦辺雅之、油谷浩幸、深山正久、瀬戸泰之、金田篤志.
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K08729
[Presentation] 発がんに関わるエピゲノム異常誘導因子としての病原体の意義2016
- Author(s)
  松坂恵介
- Organizer
  日本環境変異原学会第45回大会
- Place of Presentation
  つくば国際会議場（茨城県、つくば市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-16K08729
[Presentation] Unique genetic and epigenetic features of gastric cancer subtypes with high-methylation or Epstein-Barr virus infection2016
- Author(s)
  Matsusaka K, Mano Y, Fukuyo M, Urabe M, Rahmutulla B, Sakai E, Aburatani H, Seto Y, Fukayama M, Kaneda A.
- Organizer
  The75th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08729
[Presentation] 胃がんDNA異常メチル化に対する配列選択的DNA結合小分子を用いた新規抗がん療法の開発.2015
- Author(s)
  松坂恵介、篠原憲一、福世真樹、金田篤志．
- Organizer
  第１回AMEDがん若手研究者ワークショップ
- Place of Presentation
  国立オリンピック記念青少年総合センター（東京都・渋谷区）
- Year and Date
  2015-11-04
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] 胃がんにおいてEBV感染がもたらすDNAメチル化・ヒストン修飾変化2015
- Author(s)
  船田さやか、松坂恵介、山中遼太、仲木竜、油谷浩幸、深山正久、金田篤志．
- Organizer
  第１回AMEDがん若手研究者ワークショップ
- Place of Presentation
  国立オリンピック記念青少年総合センター（東京都・渋谷区）
- Year and Date
  2015-11-04
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] エピソーマル型プラスミドベクターの長期培養後にみられるde novo DNAメチル化誘導の解析2015
- Author(s)
  菅谷茂、松坂恵介、船田さやか、眞野恭伸、福世真樹、喜多和子、金田篤志
- Organizer
  第３８回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Two subtypes with distinct molecular features in colorectal neoplasms of familial adenomatous polyposis.2015
- Author(s)
  Kiyoko Takane, Keisuke Matsusaka, Satoshi Ota, Eiji Sakai, Masaki Fukuyo, Kazuyuki Matsushita, Hideaki Miyauchi, Hiroyuki Aburatani, Yukio Nakatani, Tadatoshi Takayama, Hisahiro Matsubara, Atsushi Kaneda.
- Organizer
  74th Annual Meeting of Japan Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] DNAメチル化情報による遺伝性大腸癌の層別化2015
- Author(s)
  高根希世子、松坂恵介、太田聡、酒井英嗣、福世真樹、松下一之、宮内英聡、油谷浩幸、中谷行雄、高山忠利、松原久裕、金田篤志
- Organizer
  第７０回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松（静岡県・浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Genetic aberration analysis combined with DNA methylome characterization in gastric cancer.2015
- Author(s)
  Keisuke Matsusaka, Masaki Fukuyo, Masayuki Urabe, Bahityar Rahmutulla, Eiji Sakai, Hiroyuki Aburatani, Masashi Fukayama, Atsushi Kaneda.
- Organizer
  74th Annual Meeting of Japan Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] DNAメチル化情報による遺伝性大腸癌の層別化2015
- Author(s)
  高根希世子、松坂恵介、太田聡、酒井英嗣、福世真樹、松下一之、宮内英聡、油谷浩幸、中谷行雄、高山忠利、松原久裕、金田篤志．
- Organizer
  第１回AMEDがん若手研究者ワークショップ
- Place of Presentation
  国立オリンピック記念青少年総合センター（東京都・渋谷区）
- Year and Date
  2015-11-04
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Dynamic alteration of distribution of hydroxymethylcytosine during DNA methylation alteration by EB virus infection.2015
- Author(s)
  Hiroe N Fukuyo, Masaki Fukuyo, Keisuke Matsusaka, Sayaka Funata, Masashi Fukayama, Toshiki Watanabe, Atsushi Kaneda.
- Organizer
  74th Annual Meeting of Japan Cancer Association.
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Epstein-Barrウイルス感染による新規DNAメチル化とヒストン活性化マーク消失の相関2015
- Author(s)
  船田さやか、松坂恵介、山中遼太、仲木竜、油谷浩幸、深山正久、金田篤志
- Organizer
  第３８回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Characterization of DNA methylation abnormalities in esophagogastric junction adenocarcinoma and background epithelium.2015
- Author(s)
  Masayuki Urabe, Keisuke Matsusaka, Tetsuo Ushiku, Masaki Fukuyo, Hiroharu Yamashita, Yasuyuki Seto, Masashi Fukayama, Atsushi Kaneda.
- Organizer
  74th Annual Meeting of Japan Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Four DNA methylation epigenotypes of gastric cancer with distinct etiology and genetic features, revealed by genome-wide analyses.2015
- Author(s)
  Atsushi Kaneda, Keisuke Matsusaka, Sayaka Funata, Masaki Fukuyo, Hiroe Namba-Fukuyo, Masayuki Urabe, Masashi Fukayama.
- Organizer
  74th Annual Meeting of Japan Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Genetic aberration analysis combined with DNA methylome characterization in gastric cancer2015
- Author(s)
  Keisuke Matsusaka, Masaki Fukuyo, Masayuki Urabe, Bahityar Rahmutulla, Eiji Sakai, Hiroyuki Aburatani, Masashi Fukayama, Atsushi Kaneda
- Organizer
  74th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  愛知県名古屋市名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860257
[Presentation] Epstein-Barr virus infection induces de novo DNA methylation in non-cancerous gastric epithelial cells.2014
- Author(s)
  Keisuke Matsusaka, Sayaka Funata, Hiroyuki Aburatani, Masashi Fukayama, Atsushi Kaneda.
- Organizer
  73rd Annual Meeting of Japan Cancer Association
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Epstein - Barr virus infection induces global DNA methylation in gastric cells2014
- Author(s)
  Matsusaka K
- Organizer
  Epstein - Barr virus 50th Anniversary Conference
- Place of Presentation
  Oxford, U.K
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] Inverse correlation between active histone marks and induction of DNA methylation during Epstein-Barr virus infection2014
- Author(s)
  Sayaka Funata, Keisuke Matsusaka, Ryota Yamanaka, Hiroyuki Aburatani, Masashi Fukayama、 Atsushi Kaneda
- Organizer
  73rd Annual Meeting of Japan Cancer Association
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] DNA methylation accumulation at early stage of carcinogenesis, predetermining future cancer phenotypes2014
- Author(s)
  Atsushi Kaneda, Keisuke Matsusaka, Eiji Sakai, Koichi Yagi, Sayaka Funata, Hiroyuki Aburatani, Atsushi Nakajima, Masashi Fukayama
- Organizer
  73rd Annual Meeting of Japan Cancer Association
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Time - series DNA methylation analysis in gastric cell following Epstein - Barr virus infection2013
- Author(s)
  Matsusaka K, Funata S, Aburatani H, Fukayama M, Kaneda A
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] Time-series DNA methylation analysis in gastric cell following Epstein-Barr virus infection2013
- Author(s)
  Keisuke Matsusaka, Sayaka Funata, Hiroyuki Aburatani, Masashi Fukayama, Atsushi Kaneda
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜パシフィコ
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] Time-series DNA methylation analysis in gastric cell following Epstein-Barr virus infection2013
- Author(s)
  Keisuke Matsusaka, Sayaka Funata, Hiroyuki Aburatani, Masashi Fukayama, Atsushi Kaneda
- Organizer
  The 4th JCA-AACR Special Conference
- Place of Presentation
  Tokyo Bay Maihama Hotel Club Resort, Chiba, Japan
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] Time - series DNA methylation analysis in gastric cell following Epstein - Barr virus infection2013
- Author(s)
  Matsusaka K, Funata S, Aburatani H, Fukayama M, Kaneda A
- Organizer
  The 4th JCA - AACR Special Conference
- Place of Presentation
  Tokyo Bay Maihama Hotel Club Resort, Chiba, Japan
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] 感染早期における宿主細胞とEBVのDNAメチル化の継時的解析2013
- Author(s)
  松坂恵介，金田篤志，船田さやか，深山正久
- Organizer
  第102回日本病理学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] DNA methylation alteration of Epstein - Barr virus genome and host cellular genome in EBV infection to gastric cells2012
- Author(s)
  Matsusaka K, Kaneda A, Funata S, Takada K, Aburatani H, Fukayama M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] DNA methylation alteration of Epstein-Barr virus genome and host cellular genome in EBV infection to gastric cells2012
- Author(s)
  Matsusaka K, Kaneda A, Funata S, Takada K, Aburatani H, Fukayama M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] Epstein - Barr virus関連胃癌及び非関連胃癌におけるARID1A発現消失の臨床病理学的検討2012
- Author(s)
  阿部浩幸,前田大地,日野るみ,大嶽雄也,磯貝まや,牛久綾,松坂恵介,国田朱子,牛久哲男,宇於崎宏,岩崎善毅,立石陽子,比島恒和,石川俊平,深山正久
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-26
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] Epstein - Barr virus関連胃癌及び非関連胃癌におけるARID1A発現消失の臨床病理学的検討2012
- Author(s)
  阿部浩幸,前田大地,日野るみ,大嶽雄也,磯貝まや,牛久綾,松坂恵介,国田朱子,牛久哲男,宇於崎宏,岩崎善毅,立石陽子,比島恒和,石川俊平,深山正久
- Organizer
  第9回EBウイルス研究会
- Place of Presentation
  米子
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] EBV陽性胃癌におけるDNAメチル化の網羅的解析2012
- Author(s)
  松坂恵介,金田篤志,永江玄太,牛久哲男,宇於崎宏,瀬戸泰之,高田賢藏,油谷浩幸,深山正久
- Organizer
  第9回EBウイルス研究会
- Place of Presentation
  米子
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-24790347
[Presentation] DNA methylation alteration of Epstein-Barr virus genome and host cellular genome in EBV infection to gastric cells.2012
- Author(s)
  Matsusaka K
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌，札幌市教育文化会館
- Data Source
  KAKENHI-PROJECT-20249022
[Presentation] Identification of DNA methylation epigenotype specific to Epstein-Barr virus-positive gastric cance2011
- Author(s)
  Matsusaka K, Fukayama M, et al.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-20249022
[Presentation] EBV陽性胃癌におけるDNAメチル化の網羅的解析2011
- Author(s)
  松坂恵介、深山正久, 他
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜パシフィコ(神奈川県横浜市)
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-20249022
[Presentation] 胃癌におけるDNAメチル化の網羅的解析.2009
- Author(s)
  松坂恵介, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20249022
[Presentation] 胃癌におけるDNAメチル化の網羅的解析2009
- Author(s)
  松坂恵介, 他
- Organizer
  第3回エピジェネティクス研究会年会
- Place of Presentation
  東京学術総合センター
- Data Source
  KAKENHI-PROJECT-20249022
[Presentation] Epstein-Barr virus関連胃癌におけるDNAメチル化の網羅的解析.2008
- Author(s)
  松坂恵介ら
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20249022
[Presentation] デジタルPCRを用いた胃癌におけるHER2遺伝子の定量的解析
- Author(s)
  松坂恵介，石川俊平，金子伸行，牛久哲男，深山正久
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島県広島市）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26860257
[Presentation] ホスト細胞内における外来DNAのエピゲノム状態の可視化
- Author(s)
  菅谷茂, 松坂恵介, 船田さやか, 喜多和子, 金田篤志
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26670595
[Presentation] Epstein-Barr virus infection induces de novo DNA methylation in non-cancerous gastric epithelial cells
- Author(s)
  Keisuke Matsusaka, Sayaka Funata, Hiroyuki Aburatani, Masashi Fukayama, Atsushi Kaneda
- Organizer
  73rd Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Pacifico Yokohama（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860257
[]
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[]
[]

1. FUKAYAMA Masashi (70281293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. UOZAKI Hiroshi (10296246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SAKATANI Takashi (50431903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HINO Rumi (60451770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. USHIKU Tetsuo (60376415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIKAWA Teppei (80451772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KIKUCHI Yoshinao (90512260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAYA Takeo (80512277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHINOZAKI Aya (60581824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KUNITA Akiko (50608768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Kaneda Atsushi (10313024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
12. FUNATA Sayaka (80756081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
13. OKABE Atsushi (80778118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 沖元謙一郎 (30770739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松村倫明 (00514530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUKUYO Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
17. NAKASEKO Chiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. SAKAIDA Emiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 石川俊平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
21. 中島崇裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 松原久裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 浜窪隆雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 武内正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 大和田千桂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 三村尚也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 塚本祥吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 竹田勇輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 松下一之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 後藤明輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 関元昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 三澤清

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 山下裕玄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUSAKA Keisuke 松坂 恵介

Research Projects

Research Products

Co-Researchers

野生型p53を保持するMSI胃癌の発癌機構の解明とその治療戦略の確立Principal Investigator

Principal Investigator

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Review Section

Research Institution

社会実装可能な人工知能による画期的十二指腸腫瘍risk層別内視鏡診断システムの開発

Principal Investigator

Project Period (FY)

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Research Institution

臓器横断的な孤発性MSI陽性腫瘍の本態解明と治療戦略の構築Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Clarification of genome/epigenome interaction in microsatellite instable gastric cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of factors contributing to epigenetic alteration and maintenance in EBV infection.Principal Investigator

Principal Investigator

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Research Field

Research Institution

Clarification of mechanism in induction of DNA methylation using Epstein-Barr virus infection experimentPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Analysis on alterated chromatin status of viral genome in the host cells.

Principal Investigator

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Research Institution

Comprehensive DNA methylation analysis in the close interaction between Epstein-Barr virus and host cellPrincipal Investigator

Principal Investigator

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Research Institution

EB virus-associated gastric carcinoma. Molecular mechanisms of DNA hypermethylation and strategy for gastric cancer therapy.

Principal Investigator

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[Book] 胃と腸 58(10)2023

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[Book] DNA and Histone Methylation as Cancer Targets2017

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[Book] 病理と臨床2016

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[Book] 成人病と生活習慣病2013

Author(s)

Total Pages

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Data Source

[Book] 成人病と生活習慣病2013

MATSUSAKA Keisuke 松坂恵介