Hashimoto Naoki 橋本直樹

… Alternative Names

HASHIMOTO Naoki 橋本直樹

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Researcher Number	40615895
Other IDs
Affiliation (Current)	2025: 北海道大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 北海道大学, 医学研究院, 准教授 2019 – 2020: 北海道大学, 医学研究院, 講師 2018: 北海道大学, 医学研究院, 助教 2017: 北海道大学, 医学(系)研究科(研究院), 客員研究員 2015: 北海道大学, 病院精神科神経科, 助教 … More 2014: 北海道大学, 医学(系)研究科(研究院), その他 2014: 北海道大学, 医学(系)研究科(研究院), 客員研究員 2013: 北海道大学, 大学院医学研究科, 助教 2012 – 2013: 北海道大学, 医学(系)研究科(研究院), 助教 2012: 北海道大学, 大学院・医学研究科・精神医学分野, 北海道大学保健管理センター, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science Except Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator 統合失調症 / 社会機能 / MRI / BNSS / 陰性症状 / バッテリー検査 / 大うつ病性障害 / 双極性障害 / 社会認知 / 負の信念 … More / 神経認知機能 / 社会認知機能 / RBL課題 / EBDM課題 / コストベネフィット分析 / 強化学習 / 行動課題 / 評価尺度 / 標準化 / 陽性症状 / 妥当性 / 信頼性 / PANSS / 脳画像 / 認知機能障害 / ドパミン / 難治性うつ病 / 報酬予測課題 / 報酬系 / functional MRI / うつ病 … More Except Principal Investigator 認知機能障害 / 統合失調症 / 災害精神医学 / モデル動物 / 酸化ストレス / ミクログリア / ミエリン鞘 / CCL11 / ケモカイン / 神経炎症 / e-ラーニング / メンタルヘルス・ファーストエイド / 遠隔教育 / e-learning / 健康教育 / 地域保健 / 社会精神医学 / at risk mental state / coherent motion / 社会知覚 / 外発課題 / 内発課題 / スイッチング課題 / ARMS / 事象関連電位 / Sternberg課題 / 事象関連同期 / 作業記憶 / 遂行機能 / biological motion / 中間表現型 / 精神病発症高リスク状態 (ARMS) / 社会医学 / 社会系心理学 / 社会福祉関係 / 臨床 / 医療・福祉 Less

Comparison of social cognitive dysfunction in schizophrenia, bipolar disorder, and major depressive disorderPrincipal Investigator
- Principal Investigator
  
  橋本直樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Hokkaido University
Pathophysiology of cognitive dysfunction in schizophrenia focusing on the hypothesis of accelerated cerebral aging by CCL11
- Principal Investigator
  
  Kusumi Ichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Hokkaido University
Effects of negative symptoms including impairment in goal generation process and social cognitive function on social function in patients with SchizophreniaPrincipal Investigator
- Principal Investigator
  
  Hashimoto Naoki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Hokkaido University
Creating a nobel assessment system of negative symptoms and exploring biological underpinnings of negative symptoms.Principal Investigator
- Principal Investigator
  
  Hashimoto Naoki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Hokkaido University
The fMRI study of reward system in the patient with major depressive disorder: Is the disturbance of the system a biological marker of treatment-resistant depression ?Principal Investigator
- Principal Investigator
  
  HASHIMOTO Naoki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hokkaido University
Construction of the education system including the remote education model to a mental health practitioner
- Principal Investigator
  
  OTSUKA Kotaro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Iwate Medical University
Systematic evaluation of endophenotypes for patients with at risk mental state and first-episode schizophrenia
- Principal Investigator
  
  KUSUMI Ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Hokkaido University
Intervention study of the educational program against the psychiatric crisis for the medical care, community mental health, and families
- Principal Investigator
  
  OTSUKA Kotaro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Iwate Medical University

All 2022 2021 2020 2019 2016 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] 統合失調症患者における動機づけ低下の生物学的基盤2021
- Author(s)
  橋本直樹、豊巻篤人、久住一郎
- Journal Title
  
  Precision Medicine
  
  Volume: 4 Pages: 79-82
- Data Source
  KAKENHI-PROJECT-20K07913
[Journal Article] A pilot validation study of the Japanese translation of the Positive and Negative Syndrome Scale (PANSS).2020
- Author(s)
  Hashimoto N, Takahashi K, Fujisawa D, Aoyama K, Nakagawa A, Okamura N, Toyomaki A, Oka M, Takanobu K, Okubo R, Narita H, Kitagawa K, Udo N, Maeda T, Watanabe S, Oyanagi Y, Miyazaki A, Ito K, Kusumi I.
- Journal Title
  
  Asian Journal of Psychiatry
  
  Volume: 54 Pages: 102210-102210
- DOI
  10.1016/j.ajp.2020.102210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07476, KAKENHI-PROJECT-17K10287
[Journal Article] Pilot Validation Study of the Japanese Translation of the Brief Negative Symptoms Scale (BNSS)2019
- Author(s)
  Hashimoto Naoki、Toyomaki Atsuhito、Oka Matsuhiko、Takanobu Keisuke、Okubo Ryo、Narita Hisashi、Kitagawa Kan、Udo Niki、Maeda Tamaki、Watanabe Shinya、Oyanagi Yuka、Miyazaki Akane、Ito Koki、Kusumi Ichiro
- Journal Title
  
  Neuropsychiatric Disease and Treatment
  
  Volume: Volume 15 Pages: 3511-3518
- DOI
  10.2147/ndt.s237449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10287, KAKENHI-PROJECT-19K21204
[Journal Article] Effectiveness of suicide prevention gatekeeper-training for university administrative staff in Japan2016
- Author(s)
  Hashimoto N, Suzuki Y, Kato TA, Fujisawa D, Sato R, Aoyama-Uehara K, Fukasawa M, Asakura S, Kusumi I, Otsuka K
- Journal Title
  
  Psychiatry Clin Neurosci
  
  Volume: 70 Issue: 1 Pages: 62-70
- DOI
  10.1111/pcn.12358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09853, KAKENHI-PROJECT-25461781
[Journal Article] 精神病症状に対するメンタルヘルス・ファーストエイド2016
- Author(s)
  橋本直樹
- Journal Title
  
  治療
  
  Volume: 98(5) Pages: 656-660
- Data Source
  KAKENHI-PROJECT-25461781
[Journal Article] 私の診療経験から　こころの応急対応(メンタルヘルス・ファーストエイド)　-日常臨床場面における、うつ病の早期介入と自殺予防-2014
- Author(s)
  加藤隆弘、大塚耕太郎、鈴木友理子、藤澤大介、佐藤玲子、青山久美、橋本直樹、鈴木志麻子、神庭重信
- Journal Title
  
  臨床と研究
  
  Volume: 91(2) Pages: 289-294
- NAID
  40019987192
- Data Source
  KAKENHI-PROJECT-25461781
[Journal Article] Effectiveness of brief suicide management training program for medical residents in Japan: A cluster randomized controlled trial.2014
- Author(s)
  Suzuki Y, Kato TA, Sato R, Fujisawa D, Aoyama-Uehara K, Hashimoto N, Yonemoto N, Fukasawa M, Otsuka　K.
- Journal Title
  
  Epidemiology and Psychiatric Sciences
  
  Volume: 23（2） Pages: 167-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461781
[Journal Article] こころの応急対応(メンタルヘルス・ファーストエイド)　日常臨床場面における、うつ病の早期介入と自殺予防2014
- Author(s)
  加藤隆弘, 大塚耕太郎, 鈴木友理子, 藤澤大介, 佐藤玲子, 青山久美, 橋本直樹, 鈴木志麻子, 神庭重信
- Journal Title
  
  臨牀と研究
  
  Volume: 91(2) Pages: 289-294
- Data Source
  KAKENHI-PROJECT-25461781
[Journal Article] Neurocognitive impairments and quality of life in unemployed patients with remitted major depressive disorder.2013
- Author(s)
  Shimizu Y, Kitagawa N, Mitsui N, Fujii Y, Toyomaki A, Hashimoto N, Kako Y, Tanaka T, Asakura S, Kusumi I
- Journal Title
  
  Psychiatry Research
  
  Volume: 210 Issue: 3 Pages: 913-918
- DOI
  10.1016/j.psychres.2013.08.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860981
[Journal Article] Severity of generalized social anxiety disorder correlates with low executive functioning.2013
- Author(s)
  Fujii Y, Kitagawa N, Shimizu Y, Mitsui N, Toyomaki A, Hashimoto N, Kako Y, Tanaka T, Asakura S, Koyama T, Kusumi I.
- Journal Title
  
  neuroscience letter
  
  Volume: 543 Pages: 42-46
- DOI
  10.1016/j.neulet.2013.02.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860981
[Journal Article] Suicide Intervention Skills Among Japanese Medical Residents.2013
- Author(s)
  Fujisawa D, Suzuki, Y., Kato, A.T., Hashimoto, N., Sato, R., Aoyama-Uehara, K., Fukasawa, M., Tomita, M., Watanabe, K., Kashima, H., Otsuka, K.
- Journal Title
  
  Academic Psychiatry
  
  Volume: 37 Issue: 6 Pages: 402-407
- DOI
  10.1176/appi.ap.10110154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791252, KAKENHI-PROJECT-25860981
[Journal Article] Discrepancy of neural response between exogenous and endogenous task switching: an event-related potentials study2012
- Author(s)
  Miyajima M
- Journal Title
  
  Neuroreport
  
  Volume: 23(11) Issue: 11 Pages: 642-646
- DOI
  10.1097/wnr.0b013e328354b066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23330201, KAKENHI-PROJECT-23330269, KAKENHI-PROJECT-23591687, KAKENHI-PROJECT-23659341, KAKENHI-PROJECT-23791306
[Journal Article] The effect of explicit instruction on Japanese Verbal Learning Test in patients with schizophrenia2011
- Author(s)
  Hashimoto N, Matsui M, Kusumi I, Toyomaki A, Ito K, Kako Y, Koyama T
- Journal Title
  
  Psychiatry Res
  
  Volume: 188 Issue: 2 Pages: 289-290
- DOI
  10.1016/j.psychres.2010.06.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591687
[Journal Article] The effect of explicit instruction on Japanese Verbal Learning Test in patients　with schizophrenia2011
- Author(s)
  Hashimoto N, Matsui M, Kusumi I, Toyomaki A, Ito K, Kako Y, Koyama T
- Journal Title
  
  Psychiatry Res
  
  Volume: 188 Pages: 289-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] 統合失調症患者の強化学習課題における障害に関する研究2022
- Author(s)
  野原万梨子、橋本直樹、豊巻敦人、服部幸子、國峯桜、秋山久、久住一郎
- Organizer
  BPCNPNPPP４学会合同年会
- Data Source
  KAKENHI-PROJECT-20K07913
[Presentation] 日本語版BNSSの信頼性、妥当性評価2019
- Author(s)
  橋本直樹、岡松彦、高信径介、成田尚、北川寛、宇土仁木、渡辺晋也、大柳有加、宮崎茜、伊藤侯輝、久住一郎
- Organizer
  第14回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-17K10287
[Presentation] 日本語版PANSSの信頼性、妥当性評価2019
- Author(s)
  橋本直樹、岡松彦、高信径介、成田尚、北川寛、宇土仁木、渡辺晋也、大柳有加、宮崎茜、伊藤侯輝、久住一郎
- Organizer
  第１１５回日本精神神経学会
- Data Source
  KAKENHI-PROJECT-17K10287
[Presentation] 日本語版BNSSの信頼性、妥当性評価2019
- Author(s)
  橋本直樹、岡松彦、高信径介、成田尚、北川寛、宇土仁木、渡辺晋也、大柳有加、宮崎茜、伊藤侯輝、久住一郎
- Organizer
  第１４回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-17K10287
[Presentation] 日本語版PANSSの信頼性、妥当性評価2019
- Author(s)
  橋本直樹、岡松彦、高信径介、成田尚、北川寛、宇土仁木、渡辺晋也、大柳有加、宮崎茜、伊藤侯輝、久住一郎
- Organizer
  第115回日本精神神経学会
- Data Source
  KAKENHI-PROJECT-17K10287
[Presentation] Difference of reward system activation in patients with schizophrenia treated with olanzapine, blonanserine and aripiprazole-2nd report.2013
- Author(s)
  Naoki Hashimoto, Atsuhito Toyomaki, Tamaki Miyamoto, Ichiro Kusumi.
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  San Diego Convention Center　(San Diego, USA)
- Data Source
  KAKENHI-PROJECT-25860981
[Presentation] 統合失調症における作業記憶課題遂行時の事象関連電位・事象関連同期の異常2013
- Author(s)
  宮島真貴、豊巻敦人、清水祐輔、橋本直樹、宮崎茜、久住一郎
- Organizer
  第47回日本作業療法学会
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] 統合失調症における作業記憶課題遂行時の事象関連電位・事象関連同期の異常2013
- Author(s)
  宮島真貴, 豊巻敦人, 清水祐輔, 橋本直樹, 宮崎茜, 久住一郎
- Organizer
  第47回日本作業療法学会
- Place of Presentation
  大阪国際会議場, 大阪
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] Difference of reward system activation in patients with schizophrenia treated with olanzapine, blonanserin and aripiprazole-2nd report2013
- Author(s)
  Naoki Hashimoto, Atsuhito Toyomaki, Tamaki Miyamoto, Ichiro Kusumi
- Organizer
  43th Annual Meeting Society for Neuroscience
- Place of Presentation
  San Diego Convention Center (San Diego, CA, USA)
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] Working memory deficits in schizophrenia : an event-related potentials study2013
- Author(s)
  Miyazaki A ,Toyomaki A, Hashimoto N, Kusumi I
- Organizer
  11th World Congress of Biological Psychiatry
- Place of Presentation
  Kyoto International Conference Center (Kyoto, Japan)
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] Working memory deficits in schizophrenia: an event-related potentials study2013
- Author(s)
  Miyazaki A, Toyomaki A, Hashimoto N, Kusumi I
- Organizer
  11th World Congress of Biological Psychiatry
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] Difference of reward system activation in patients with schizophrenia treated with olanzapine, blonanserin and aripiprazole-2nd report2013
- Author(s)
  Naoki Hashimoto, Atsuhito Toyomaki, Tamaki Miyamoto, Ichiro Kusumi
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] 統合失調症患者におけるcoherent motion 知覚とbiological motion知覚の関連および臨床背景との相関の検討2011
- Author(s)
  橋本直樹、久住一郎、豊巻敦人、賀古勇輝、朴　秀賢、伊藤候輝、小山　司
- Organizer
  第6回日本統合失調症学会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23591687
[Presentation] 初期臨床研修医における、患者の自殺行動への対処スキル2011
- Author(s)
  藤澤大介、鈴木友理子、加藤隆弘、橋本直樹、佐藤玲子、上原久美、深澤舞子、冨田真幸、渡邊衡一郎、鹿島晴雄、大塚耕太郎
- Organizer
  第107回日本精神神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591296
[Presentation] 初期臨床研修医における、患者の自殺行動への対処スキル.2011
- Author(s)
  藤澤大介、鈴木友理子、加藤隆弘、橋本直樹、佐藤玲子、上原久美、深澤舞子、冨田真幸、渡邊衡一郎、鹿島晴雄、大塚耕太郎
- Organizer
  第1回メンタルヘルスリーダーシッププログラム
- Place of Presentation
  千葉
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-22591296
[Presentation] 初期臨床研修医における、患者の自殺行動への対処スキル2011
- Author(s)
  藤澤大介、鈴木友理子、加藤隆弘、橋本直樹、佐藤玲子、上原久美、深澤舞子、冨田真幸、渡邊衡一郎、鹿島晴雄、大塚耕太郎
- Organizer
  第1回メンタルヘルスリーダーシッププログラム
- Place of Presentation
  千葉
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-22591296

1. YOYOMAKI Atsuhito (70515494)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. OTSUKA Kotaro (00337156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. SUZUKI Yuriko (70425693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. FUJISAWA Daisuke (30327639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. YONEMOTO Naohiro (90435727)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. KATO Takahiro (70546465)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. KUSUMI Ichiro (30250426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. AOYAMA Kumi (30715199)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. SATO Ryoko

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
10. IWATO Sayaka (10552739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Koki (40455663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. 石川修平 (30880091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 扇谷昌宏 (60636455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 古賀農人 (70744936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大久保亮 (00803470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUZUKI Shimako

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. KUROSAWA Mie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KAMISAKI Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KOBARA Keiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. CHO Tetuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 朝倉聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Naoki 橋本 直樹

HASHIMOTO Naoki 橋本 直樹

Research Projects

Research Products

Co-Researchers

Comparison of social cognitive dysfunction in schizophrenia, bipolar disorder, and major depressive disorderPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiology of cognitive dysfunction in schizophrenia focusing on the hypothesis of accelerated cerebral aging by CCL11

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of negative symptoms including impairment in goal generation process and social cognitive function on social function in patients with SchizophreniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creating a nobel assessment system of negative symptoms and exploring biological underpinnings of negative symptoms.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The fMRI study of reward system in the patient with major depressive disorder: Is the disturbance of the system a biological marker of treatment-resistant depression ?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of the education system including the remote education model to a mental health practitioner

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Systematic evaluation of endophenotypes for patients with at risk mental state and first-episode schizophrenia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Intervention study of the educational program against the psychiatric crisis for the medical care, community mental health, and families

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 統合失調症患者における動機づけ低下の 生物学的基盤2021

Author(s)

Journal Title

Data Source

[Journal Article] A pilot validation study of the Japanese translation of the Positive and Negative Syndrome Scale (PANSS).2020

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DOI

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[Journal Article] Pilot Validation Study of the Japanese Translation of the Brief Negative Symptoms Scale (BNSS)2019

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[Journal Article] Effectiveness of suicide prevention gatekeeper-training for university administrative staff in Japan2016

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[Journal Article] 精神病症状に対するメンタルヘルス・ファーストエイド2016

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[Journal Article] 私の診療経験から こころの応急対応(メンタルヘルス・ファーストエイド) -日常臨床場面における、うつ病の早期介入と自殺予防-2014

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NAID

Hashimoto Naoki 橋本直樹

HASHIMOTO Naoki 橋本直樹

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[Journal Article] 私の診療経験から　こころの応急対応(メンタルヘルス・ファーストエイド)　-日常臨床場面における、うつ病の早期介入と自殺予防-2014

[Journal Article] こころの応急対応(メンタルヘルス・ファーストエイド)　日常臨床場面における、うつ病の早期介入と自殺予防2014

[Journal Article] The effect of explicit instruction on Japanese Verbal Learning Test in patients　with schizophrenia2011