IWATAKE Mayumi 岩竹真弓

Researcher Number	40624614
Other IDs
Affiliation (Current)	2025: 名古屋大学, 未来社会創造機構, 特任准教授 2025: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 2023: 名古屋大学, 未来社会創造機構, 特任准教授 2023: 名古屋大学, 未来社会創造機構, 特任講師 2020 – 2022: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2021: 長崎大学, 医歯薬学総合研究科(歯学系), 技術職員 2017 – 2019: 長崎大学, 医歯薬学総合研究科(歯学系), 技術職員
Review Section/Research Field	Principal Investigator Basic Section 55040:Respiratory surgery-related / Surgical dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Basic Section 53030:Respiratory medicine-related / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 臍帯由来間葉系幹細胞 / 臍帯MSC / 骨再生 / Ⅱ型肺胞オルガノイド / 組織再生 / デザイナー細胞 / 細胞治療 / 肺オルガノイド / 間葉系幹細胞 / 臍帯 / 骨芽細胞分化 / アクチン重合 / 骨芽細胞分化誘導 … More Except Principal Investigator … More 脱細胞化 / 肺線維症 / 人工気管 / アロ抗原 / 制御性T細胞 / 免疫寛容 / 肺移植 / 肺胞オルガノイド / in vitro モデル / マイクロ流体デバイス / オルガノイド / 疾患モデル / 肺再生 / マクロファージ / 再生肺 / HLA-G / 間葉系幹細胞 / バイオマテリアル / 脱細胞化組織骨格 / 移植免疫 / 臍帯血 / ３Dバイオプリンター / 気管再生 / 3Dバイオプリンティング / 臍帯組織 / 臓器移植 / 再生医療 / 気管移植 / ゼラチンマイクロスフィア / ゼラチンマイクロスフェア / 成長因子 / 細胞凝集 / バイオ3Dプリンター / 軟骨分化 / 幹細胞 / デザイナー細胞 / 細胞治療 / 骨再生 / iPS細胞 / 巨核球 Less

Establishment of an in vitro human pulmonary fibrosis model using a novel culture system of alveolar organoids
- Principal Investigator
  
  土肥良一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagasaki University
Operational tolerance induction by alloantigen-induced Treg cell therapy in rat lung transplantation
- Principal Investigator
  
  土谷智史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  University of Toyama
オルガノイド由来II型肺細胞とデザイナー臍帯MSCの共移植による革新的細胞治療の創出Principal Investigator
- Principal Investigator
  
  岩竹真弓
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagoya University
HLA-G誘導MSCによる局所免疫の抑制機序解析と免疫抑制性バイオマテリアル開発
- Principal Investigator
  
  田上幸憲
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
Ex vivo再生肺による肺線維症モデルとマクロファージの役割の解明
- Principal Investigator
  
  永安武
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
iPS細胞由来巨核球を骨誘導のデザイナー細胞として応用した新しい骨再生治療開発
- Principal Investigator
  
  住田吉慶
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nagasaki University
Development of an Artificial Cylindrical Organ Fabrication Method Using Gelatin Microspheres with Growth Factor Administration
- Principal Investigator
  
  Uchida Fumitake
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Nagasaki University
Establishment of tracheal regeneration method using cells extracted from umbilical cord tissue
- Principal Investigator
  
  OYAMA Shozaburo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
Actin Dynamics-associated Induction of Osteoblast Differentiation in Umbilical Cord-derived Mesenchymal Stem CellsPrincipal Investigator
- Principal Investigator
  
  Iwatake Mayumi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nagoya University
  Nagasaki University
Development of new bone regeneration method by collagen gel culture using umbilical cord MSCPrincipal Investigator
- Principal Investigator
  
  IWATAKE Mayumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University

All 2024 2023 2022 2021 2020 2018 2017

All Journal Article Presentation Patent

[Journal Article] Designer umbilical cord-stem cells induce alveolar wall regeneration in pulmonary disease models2024
- Author(s)
  Iwatake Mayumi、Nagamura-Inoue Tokiko、Doi Ryoichiro、Tanoue Yukinori、Ishii Mitsutoshi、Yukawa Hiroshi、Matsumoto Keitaro、Tomoshige Koichi、Nagayasu Takeshi、Tsuchiya Tomoshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15 Pages: 1-13
- DOI
  10.3389/fimmu.2024.1384718
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08977, KAKENHI-PROJECT-23K08299, KAKENHI-PROJECT-21K08907, KAKENHI-PROJECT-20KK0255
[Journal Article] Timing of Mesenchymal Stromal Cell Therapy Defines its Immunosuppressive Effects in a Rat Lung Transplantation Model2023
- Author(s)
  Tanoue Yukinori、Tsuchiya Tomoshi、Miyazaki Takuro、Iwatake Mayumi、Watanabe Hironosuke、Yukawa Hiroshi、Sato Kazuhide、Hatachi Go、Shimoyama Koichiro、Matsumoto Keitaro、Doi Ryoichiro、Tomoshige Koichi、Nagayasu Takeshi
- Journal Title
  
  Cell Transplantation
  
  Volume: 32 Pages: 1-14
- DOI
  10.1177/09636897231207177
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08977
[Journal Article] Donor and Recipient Adipose-Derived Mesenchymal Stem Cell Therapy for Rat Lung Transplantation2022
- Author(s)
  Shimoyama Koichiro、Tsuchiya Tomoshi、Watanabe Hironosuke、Ergalad Abdelmotagaly、Iwatake Mayumi、Miyazaki Takuro、Hashimoto Yasumasa、Hsu Yu-I.、Hatachi Go、Matsumoto Keitaro、Ishii Mitsutoshi、Mizoguchi Satoshi、Doi Ryoichiro、Tomoshige Koichi、Yamaoka Tetsuji、Nagayasu Takeshi
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 54 Issue: 7 Pages: 1998-2007
- DOI
  10.1016/j.transproceed.2022.05.038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08907, KAKENHI-PROJECT-22K08977
[Journal Article] Gene-Activated Matrix with Self-Assembly Anionic Nano-Device Containing Plasmid DNAs for Rat Cranial Bone Augmentation2021
- Author(s)
  Masahito Hara,Yoshinori Sumita,Yukinobu Kodama,Mayumi Iwatake, Hideyuki Yamamoto,Rena Shido,Shun Narahara,Takunori Ogaeri,Hitoshi Sasaki and Izumi Asahina
- Journal Title
  
  Materials
  
  Volume: 14 Issue: 22 Pages: 22-22
- DOI
  10.3390/ma14227097
- NAID
  120007186847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23059, KAKENHI-PROJECT-17H01604, KAKENHI-PROJECT-20K10010
[Journal Article] Gene-activated matrix harboring a miR20a-expressing plasmid promotes rat cranial bone augmentation2021
- Author(s)
  Shido Rena、Sumita Yoshinori、Hara Masahito、Iwatake Mayumi、Narahara Shun、Umebayashi Mayumi、Miura Kei-ichiro、Kodama Yukinobu、Asahina Izumi
- Journal Title
  
  Regenerative Biomaterials
  
  Volume: 8 Issue: 2 Pages: 1-9
- DOI
  10.1093/rb/rbaa060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10010, KAKENHI-PROJECT-17H01604
[Journal Article] The Rho-specific guanine nucleotide exchange factor Plekhg5 modulates cell polarity, adhesion, migration, and podosome organization in macrophages and osteoclasts.2017
- Author(s)
  Iwatake M, Nishishita K, Okamoto K, Tsukuba T.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 359(2) Issue: 2 Pages: 415-430
- DOI
  10.1016/j.yexcr.2017.08.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-17K11847
[Journal Article] Development of a 68Ge/68Ga Generator System Using Polysaccharide Polymers and Its Application in PET Imaging of Tropical Infectious Diseases2017
- Author(s)
  Fuchigami Takeshi、Ono Hokuto、Oyadomari Kohta、Iwatake Mayumi、Hayasaka Daisuke、Akbari Masoud、Yui Katsuyuki、Nishi Kodai、Kudo Takashi、Yoshida Sakura、Haratake Mamoru、Nakayama Morio
- Journal Title
  
  ACS Omega
  
  Volume: 2 Issue: 4 Pages: 1400-1407
- DOI
  10.1021/acsomega.7b00147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15585, KAKENHI-PROJECT-15KK0348, KAKENHI-PROJECT-16H05392, KAKENHI-PROJECT-15K09895, KAKENHI-PROJECT-17K11847
[Patent] 血管内皮増殖因子を高発現する臍帯由来間葉系幹細胞の製造方法、および肺疾患治療用医薬組成物2023
- Inventor(s)
  永安武, 土谷智史, 岩竹真弓, 住田吉慶
- Industrial Property Rights Holder
  永安武, 土谷智史, 岩竹真弓, 住田吉慶
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-23K08299
[Patent] ヒト臍帯由来間葉系幹細胞から骨芽細胞の製造を目的としたアクチン重合阻害剤による分化誘導技術2020
- Inventor(s)
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Holder
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-20K10010
[Patent] 特許件2018
- Inventor(s)
  住田吉慶、岩竹真弓、朝比奈泉、小守壽文
- Industrial Property Rights Holder
  国立法人長崎大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K11847
[Patent] ヒト臍帯由来間葉系幹細胞から骨芽細胞の製造を目的としたアクチン重合阻害剤による分化誘導技術2018
- Inventor(s)
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Holder
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-006969
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K11847
[Presentation] Novel Designer Umbilical Cord-Derived Mesenchymal Stem Cells for COPD Treatment2023
- Author(s)
  M.Iwatake, T.Tsuchiya, Y.Tanoue, S.Mizoguchi, K.Matsumoto, T.Nagayasu
- Organizer
  ATS International Conference Committee
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08299
[Presentation] 分野横断研究に基づく移植用治療細胞開発の基盤技術の創出2023
- Author(s)
  岩竹真弓
- Organizer
  若手新分野創成研究ユニット・フロンティア　医工若手研究者交流会
- Invited
- Data Source
  KAKENHI-PROJECT-20K10010
[Presentation] Immunosuppressive Effects of Mesenchymal Stem Cells and the Timing of Their Use in a Rat Lung Transplantation Model2023
- Author(s)
  Y.Tanoue, T.Tsuchiya, M.Iwatake, S.Mizoguchi, K.Matsumoto, T.Nagayasu
- Organizer
  ATS International Conference Committee
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08977
[Presentation] 肺移植での細胞治療と臓器再生2023
- Author(s)
  土谷智史、田上幸憲、土肥良一郎、岩竹真弓、下山考一郎、渡邉洋之助、湯川博、永安武
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-22K08977
[Presentation] ラット肺移植モデルにおける免疫抑制を目的とした間葉系幹細胞治療の投与タイミングの検討2023
- Author(s)
  田上　幸憲、土谷　智史、岩竹　真弓、宮﨑　拓郎、渡邉　洋之助、佐藤　和秀、湯川　博、畑地　豪、下山　孝一郎、松本　桂太郎、朝重　耕一、土肥　良一郎、永安　武
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-22K08977
[Presentation] 臓器骨格を使用した呼吸器系再生研究における細胞外マトリックスの重要性2023
- Author(s)
  土谷智史、土肥良一郎、岩竹真弓、橋本泰匡、湯川博、永安武
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-22K08977
[Presentation] ラットアロ肺移植モデルにおける移植前後の脂肪由来間葉系幹細胞投与とＴ -reg 細胞の動態2022
- Author(s)
  土谷智史、田上幸憲、下山孝一郎、渡邉洋之助、岩竹真弓、宮崎拓郎、湯川博、永安武
- Organizer
  第48回日本臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08977
[Presentation] 臍帯由来間葉系幹細胞を応用した新規COPD治療細胞の創製2022
- Author(s)
  岩竹真弓、土谷智史、長村登紀子、松本桂太郎、土肥良一郎、宮﨑拓郎，朝重耕一、永安武
- Organizer
  第48回日本臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K10010
[Presentation] アクチン脱重合型臍帯由来間葉系幹細胞による新規骨再生細胞治療薬の開発2020
- Author(s)
  岩竹真弓、住田吉慶、長村登紀子、朝比奈泉
- Organizer
  第19回再生医療学会
- Data Source
  KAKENHI-PROJECT-17K11847
[Presentation] Effective Peripheral Blood Mononuclear Cells Promote the Regeneration of Radiation Injured Salivary Glands2018
- Author(s)
  3.Sumita Y，Takashi I，Iwatake M，Yoshida T，Tran SD，Asahara T, Asahina I
- Organizer
  5th TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11847
[Presentation] Actin-depolymeraization inducing by Col-1 culture accelerates osteoblastic differentiation of human umbilical cord mesenchymal stem cells.2018
- Author(s)
  Iwatake M, Sumita Y, Nagamura T, Asahina I
- Organizer
  5th TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11847

1. 永安武 (80284686)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. 土谷智史 (30437884)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
3. 松本桂太郎 (80404268)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. 住田吉慶 (50456654)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. 土肥良一郎 (00817786)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 長村登紀子 (70240736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 町野隆介 (90728081)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 朝重耕一 (70457547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 谷口大輔 (20773758)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 野中隆 (30606463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 田上幸憲 (60806371)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
12. 坂本憲穂 (30448493)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. Uchida Fumitake (00866270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OYAMA Shozaburo (20815972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐竹真 (60899053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 朝比奈泉 (30221039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 澤瀬隆 (80253681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 各務秀明 (80242866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 黒嶋伸一郎 (40443915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 高木克典 (90635856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 三浦清徳 (00363490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 田浦康明 (60437887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 高村祐磨 (20866636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 桂廣亮 (00894411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 佐藤香枝 (40373310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 森本充 (70544344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 江口晋 (80404218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 内田浩一郎 (80648329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 原昌士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 井上登紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 岡元邦彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 西下一久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 筑波隆幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 淵上剛志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 中山守雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 吉田さくら

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 石井光寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 宮崎拓郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IWATAKE Mayumi 岩竹 真弓

Research Projects

Research Products

Co-Researchers

Establishment of an in vitro human pulmonary fibrosis model using a novel culture system of alveolar organoids

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Operational tolerance induction by alloantigen-induced Treg cell therapy in rat lung transplantation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

オルガノイド由来II型肺細胞とデザイナー臍帯MSCの共移植による革新的細胞治療の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HLA-G誘導MSCによる局所免疫の抑制機序解析と免疫抑制性バイオマテリアル開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ex vivo再生肺による肺線維症モデルとマクロファージの役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

iPS細胞由来巨核球を骨誘導のデザイナー細胞として応用した新しい骨再生治療開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of an Artificial Cylindrical Organ Fabrication Method Using Gelatin Microspheres with Growth Factor Administration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of tracheal regeneration method using cells extracted from umbilical cord tissue

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Actin Dynamics-associated Induction of Osteoblast Differentiation in Umbilical Cord-derived Mesenchymal Stem CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new bone regeneration method by collagen gel culture using umbilical cord MSCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Designer umbilical cord-stem cells induce alveolar wall regeneration in pulmonary disease models2024

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[Journal Article] Timing of Mesenchymal Stromal Cell Therapy Defines its Immunosuppressive Effects in a Rat Lung Transplantation Model2023

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[Journal Article] Donor and Recipient Adipose-Derived Mesenchymal Stem Cell Therapy for Rat Lung Transplantation2022

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[Journal Article] Gene-Activated Matrix with Self-Assembly Anionic Nano-Device Containing Plasmid DNAs for Rat Cranial Bone Augmentation2021

IWATAKE Mayumi 岩竹真弓