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TSUCHIYA Tomoshi  土谷 智史

… Alternative Names

TSUTYA Tomoshi  土谷 智史

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Researcher Number 30437884
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8419-1478
External Links
Affiliation (Current) 2025: 長崎大学, 医歯薬学総合研究科(医学系), 客員教授
2025: 富山大学, 学術研究部医学系, 教授
Affiliation (based on the past Project Information) *help 2025: 富山大学, 学術研究部医学系, 教授
2022 – 2024: 富山大学, 学術研究部医学系, 特命教授
2022 – 2023: 長崎大学, 医歯薬学総合研究科(医学系), 客員教授
2022: 富山大学, 学術研究部医学系, 特命教授(教授クラス)
2014 – 2022: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 … More
2014: 長崎大学, 医歯薬学総合研究科(医学系), 講師
2013: 長崎大学, 大学院医歯薬学総合研究科, 講師
2011 – 2013: 長崎大学, 医歯(薬)学総合研究科, 講師
2010: 長崎大学, 医学部・歯学部付属病院, 講師
2010: 長崎大学, 医学部・歯学部附属病院, 医員
2010: Nagasaki University, 病院, 講師
2009: Nagasaki University, 病院, 助教
2007 – 2008: Nagasaki University Graduate School of Biomedical Sciences, 医学部・歯学部附属病院, 助教
2007: 長崎大学, 大学院・医歯薬学総合研究科, 医員 Less
Review Section/Research Field
Principal Investigator
Basic Section 55040:Respiratory surgery-related / Respiratory surgery / Thoracic surgery / Tumor biology and related fields / Medium-sized Section 90:Biomedical engineering and related fields
Except Principal Investigator
Basic Section 55040:Respiratory surgery-related / Thoracic surgery / Respiratory surgery / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 53030:Respiratory medicine-related / Digestive surgery
Keywords
Principal Investigator
脱細胞化 / 肺再生 / 再細胞化 / 肺移植 / 再生医学 / 移植 / バイオリアクター / 組織工学 / 肺 / 臓器工学 … More / 生理的刺激 / 肺胞バリア機能 / 接着因子 / バリア機能 / 医工学 / 移植・再生医療 / 再生医療 / 組織骨格 / マトリックス / 再生 / 肺癌 / アロ抗原 / 制御性T細胞 / 免疫寛容 / 癌 / 研究モデル / スクリーニング / 薬剤効果 / 肺がん / 疾患モデル / 脂肪由来間葉系細胞 / がんモデル / 血管内皮 / 肺胞上皮 / ニッチ / 血管 / 幹細胞 / 血管ニッチ / 生理劇刺激 / ブタ / ラット / 気管 / 細胞外マトリックス / 気管移植 / 移植免疫 / 異種移植 / 臓器移植 / 気管再生 / 脂肪肝細胞 / PARP阻害剤 / ラット肺移植 / 肺虚血再灌流 / PARP inhibitor / 脂肪幹細胞 / 虚血再灌流障害 / マイクロアレイ / 肺気腫 / 小胞体ストレス / リポポリサッカライド / アディポネクチン … More
Except Principal Investigator
再生医療 / 肺移植 / 間葉系幹細胞 / 肺再生 / 脂肪幹細胞 / 人工気管 / KGF / 脱細胞化 / 肺線維症 / オルガノイド / マイクロ流体デバイス / 臓器再生 / バイオ3Dプリンター / 外科 / 呼吸器外科学 / 臓器保存 / 創傷治癒 / 肺癌 / 低血清培養 / 急性拒絶 / 免疫抑制 / 臓側胸膜 / 深層学習 / 胸腔鏡下手術 / 臓側胸膜浸潤 / Ⅱ型肺胞オルガノイド / 組織再生 / デザイナー細胞 / 細胞治療 / 肺オルガノイド / 臍帯由来間葉系幹細胞 / 肺胞オルガノイド / in vitro モデル / 疾患モデル / マクロファージ / 再生肺 / 血管化 / オルガノイド移植 / HLA-G / バイオマテリアル / 脱細胞化組織骨格 / 移植免疫 / 急性肺障害/急性呼吸窮迫症候群 / 急性呼吸窮迫症候群 / 脂肪由来間葉系幹細胞 / 慢性閉塞性肺疾患 / 急性肺障害 / 肺胞バリア機能 / 幹細胞治療 / 呼吸器再生 / 臓器移植 / 臓器保存液 / ナノバブル / 拒絶抑制 / 免疫抑制治療 / 気管移植 / 脱細胞 / 異種移植 / Scaffold free / バイオ3Dプリンティング / 人工食道 / iPS細胞 / 3Dバイオプリンター / 小腸 / スフェロイド / Regenova / バイオ3Dプリンター / 短腸症候群 / 人工小腸 / 拒絶反応 / 脂肪肝細胞 / 気管支瘻 / 肺瘻 / 悪性胸膜中皮腫 / 胸膜欠損 / 胸膜癒着 / 中皮細胞 / 中皮 / 癒着防止 / 胸膜 / 羊膜 / 難治性気道疾患 / 人工臓器 / 気道再生 / 再生医学 / 食道再生 / 移植医療 / 移植・再生医療 / 虚血再灌流生涯 / 臓器保護 / 虚血再還流 / 人工赤血球 / regeneration / emphysema / 再生 / 肺気腫 / Gefitinib / NSCLC / EGFR / DPD / Sp1 / 非小細胞肺癌 / 気管 / 肺前駆細胞 / 気管創傷治癒 / 気道狭窄 / 細胞シート / exome解析 / 家族性肺癌 / array CGH / 染色体構造変化 / 原発多発肺癌 / 肺内転移 / 同時多発肺癌 / GFP rat / GFP / 幹細胞 / 量子ドット / 拒絶 / 免疫寛容 / 代償性肺肥大 / 気管軟骨 / 進行肺癌 / Thyroid transcription factor 1 / 肺胞サーファクタント / 制限増殖アデノウイルス / cisplatin / グルココルチコイド / Thyriod transcription factor 1 / Surfactant protein A / TTF1 / intratracheal administration / KRas / adenovirus / non small cell lung cancer / surfactant protein Less
  • Research Projects

    (33 results)
  • Research Products

    (65 results)
  • Co-Researchers

    (71 People)
  •  臨床使用を見据えた臍帯由来間葉系幹細胞による肺移植への新規細胞治療研究

    • Principal Investigator
      下山 孝一郎
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      University of Toyama
  •  Establishment of an in vitro human pulmonary fibrosis model using a novel culture system of alveolar organoids

    • Principal Investigator
      土肥 良一郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagasaki University
  •  Operational tolerance induction by alloantigen-induced Treg cell therapy in rat lung transplantationPrincipal Investigator

    • Principal Investigator
      土谷 智史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      University of Toyama
  •  オルガノイド由来II型肺細胞とデザイナー臍帯MSCの共移植による革新的細胞治療の創出

    • Principal Investigator
      岩竹 真弓
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagoya University
  •  Prediction of visceral pleural invasion in clinical stage 1 lung adenocarcinoma by using thoracoscopis images and deep learning

    • Principal Investigator
      嶋田 喜文
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      University of Toyama
  •  HLA-G誘導MSCによる局所免疫の抑制機序解析と免疫抑制性バイオマテリアル開発

    • Principal Investigator
      田上 幸憲
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  肺オルガノイド細胞療法による肺再生の基盤技術の開発

    • Principal Investigator
      吉元 崇文
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  Ex vivo再生肺による肺線維症モデルとマクロファージの役割の解明

    • Principal Investigator
      永安 武
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  Basic research on improvement of alveolar barrier function using adipose stem cells and novel cell therapy for ALI/ARDS

    • Principal Investigator
      Ishii Mitsutoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  Regenerative medicine for short bowel syndrome by artificial small Intestine composed only of autologous cells

    • Principal Investigator
      Moriyama Masaaki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nagasaki University
  •  Research on the application of iPS cells in the creation of artificial organs using a bio 3D printer

    • Principal Investigator
      Tetsuo Tomoyuki
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nagasaki University
  •  Develping of hybird tracheal trasplantation utilizing regeneratn medicine and xenotransplantation

    • Principal Investigator
      Watanabe Hironosuke
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nagasaki University
  •  Establishing the Efficacy and System Development for Clinical Application of a Novel Organ Preservation Solution Using Nanobubbles

    • Principal Investigator
      Hara Ryosuke
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  The optimization of physiological stimulation for ex vivo lung bioengineering and the establishment of an international foundational study networkPrincipal Investigator

    • Principal Investigator
      TSUCHIYA TOMOSHI
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nagasaki University
  •  Development of a Novel Respiratory Surgical Coating Material Using Freeze- and Vaccum-Dried Human Amniotic Membranes

    • Principal Investigator
      Nagayasu Takeshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  Development of rejection control method by mesenchymal stem cells using original rat lung transplantation model

    • Principal Investigator
      MIYAZAKI TAKURO
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  Establishment of hybrid vascular niche in regenerated organs using organ scaffolds and transplantation researchPrincipal Investigator

    • Principal Investigator
      TSUCHIYA TOMOSHI
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      University of Toyama
      Nagasaki University
  •  Scaffold-free artificial trachea for tracheal deiseases

    • Principal Investigator
      Matsumoto Keitaro
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Nagasaki University
  •  Regenerative medicine for esophagus using a scaffold-free structure created with bio-three-dimensional printing technology

    • Principal Investigator
      TANIGUCHI Daisuke
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagasaki University
  •  Generation of the small human lungs as the novel ex vivo lung cancer study modelsPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Tumor biology and related fields
    • Research Institution
      Nagasaki University
  •  Reducing ischemic lung perfusion injury by artificial hemoglobin

    • Principal Investigator
      MIYAZAKI Takuro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Nagasaki University
  •  Transplantation studies of tissue engineered tracha and lung regenerated from recellularized xenogeneic-decellularized scaffoldPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomoshi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory surgery
    • Research Institution
      Nagasaki University
  •  Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer

    • Principal Investigator
      NAGAYASU Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Nagasaki University
  •  Basic researches for the improvement of the fragility and the organ portection about de-and re-cellularization based regenerated lungPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory surgery
    • Research Institution
      Nagasaki University
  •  Germline mutations causing familial lung cancer

    • Principal Investigator
      MIYAZAKI Takuro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Nagasaki University
  •  Novel method for tracheal diseases and pulmonary diseases

    • Principal Investigator
      MATSUMOTO Keitaro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Nagasaki University
  •  The study of tissue protection and cell implantation effects by adipose tissue derived stromal cells for future usage in damaged or transplanted lungPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Nagasaki University
  •  New role of stem cells in the GFP-rat lung transplantation model

    • Principal Investigator
      YAMASAKI Naoya
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Nagasaki University
  •  Establishment of therapeutic strategy for synchronous double lung cancers based on molecular analysis

    • Principal Investigator
      NAGAYASU Takeshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Nagasaki University
  •  Targeting advanced non small cell lung cancer in vivo by pulmonary surfactant -adenovirus-mediated gene transfer

    • Principal Investigator
      MATSUOKA Jyunji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University
  •  A examination of KGF seat to prevent bronchpleural fistula.

    • Principal Investigator
      NAGAYASU Takeshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Nagasaki University
  •  The effects of adiponectin on lung cancer and lung diseasePrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Nagasaki University
  •  Gene therapy for lung emphysema

    • Principal Investigator
      NAGAYASU Takeshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Nagasaki University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2012 Other

All Journal Article Presentation Book Patent

  • [Book] 【再生医療の開発戦略と最新研究事例集】第12節 3次元構造を保った肺再生の取り組みと課題2019

    • Author(s)
      土谷智史
    • Total Pages
      8
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-17K19609
  • [Book] 【バイオテクノロジーシリーズ;脱細胞化組織の作製法と医療・バイオ応用】肺における脱細胞化組織骨格を利用した臓器再生研究2019

    • Author(s)
      土谷智史
    • Total Pages
      8
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-17K19609
  • [Journal Article] Designer umbilical cord-stem cells induce alveolar wall regeneration in pulmonary disease models2024

    • Author(s)
      Iwatake Mayumi、Nagamura-Inoue Tokiko、Doi Ryoichiro、Tanoue Yukinori、Ishii Mitsutoshi、Yukawa Hiroshi、Matsumoto Keitaro、Tomoshige Koichi、Nagayasu Takeshi、Tsuchiya Tomoshi
    • Journal Title

      Frontiers in Immunology

      Volume: 15 Pages: 1-13

    • DOI

      10.3389/fimmu.2024.1384718

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08977, KAKENHI-PROJECT-23K08299, KAKENHI-PROJECT-21K08907, KAKENHI-PROJECT-20KK0255
  • [Journal Article] Prediction of visceral pleural invasion of clinical stage I lung adenocarcinoma using thoracoscopic images and deep learning2023

    • Author(s)
      Shimada Yoshifumi、Ojima Toshihiro、Takaoka Yutaka、Sugano Aki、Someya Yoshiaki、Hirabayashi Kenichi、Homma Takahiro、Kitamura Naoya、Akemoto Yushi、Tanabe Keitaro、Sato Fumitaka、Yoshimura Naoki、Tsuchiya Tomoshi
    • Journal Title

      Surgery Today

      Volume: 未巻 Issue: 6 Pages: 540-550

    • DOI

      10.1007/s00595-023-02756-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K08309, KAKENHI-PROJECT-21K12110
  • [Journal Article] Timing of Mesenchymal Stromal Cell Therapy Defines its Immunosuppressive Effects in a Rat Lung Transplantation Model2023

    • Author(s)
      Tanoue Yukinori、Tsuchiya Tomoshi、Miyazaki Takuro、Iwatake Mayumi、Watanabe Hironosuke、Yukawa Hiroshi、Sato Kazuhide、Hatachi Go、Shimoyama Koichiro、Matsumoto Keitaro、Doi Ryoichiro、Tomoshige Koichi、Nagayasu Takeshi
    • Journal Title

      Cell Transplantation

      Volume: 32 Pages: 1-14

    • DOI

      10.1177/09636897231207177

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08977
  • [Journal Article] Donor and Recipient Adipose-Derived Mesenchymal Stem Cell Therapy for Rat Lung Transplantation2022

    • Author(s)
      Shimoyama Koichiro、Tsuchiya Tomoshi、Watanabe Hironosuke、Ergalad Abdelmotagaly、Iwatake Mayumi、Miyazaki Takuro、Hashimoto Yasumasa、Hsu Yu-I.、Hatachi Go、Matsumoto Keitaro、Ishii Mitsutoshi、Mizoguchi Satoshi、Doi Ryoichiro、Tomoshige Koichi、Yamaoka Tetsuji、Nagayasu Takeshi
    • Journal Title

      Transplantation Proceedings

      Volume: 54 Issue: 7 Pages: 1998-2007

    • DOI

      10.1016/j.transproceed.2022.05.038

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08907, KAKENHI-PROJECT-22K08977
  • [Journal Article] Increased In Vitro Intercellular Barrier Function of Lung Epithelial Cells Using Adipose-Derived Mesenchymal Stem/Stromal Cells2021

    • Author(s)
      Ishii Mitsutoshi、Tsuchiya Tomoshi、Doi Ryoichiro、Morofuji Yoichi、Fujimoto Takashi、Muto Hideki、Suematsu Takashi、Mori Ryoichi、Matsumoto Keitaro、Miyazaki Takuro、Tomoshige Koichi、Watanabe Hironosuke、Iwatake Mayumi、Nagayasu Takeshi
    • Journal Title

      Pharmaceutics

      Volume: 13 Issue: 8 Pages: 1264-1264

    • DOI

      10.3390/pharmaceutics13081264

    • NAID

      120007172252

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10840, KAKENHI-PROJECT-18K16424, KAKENHI-PROJECT-21H04838, KAKENHI-PROJECT-19H03747, KAKENHI-PROJECT-20K09351, KAKENHI-PROJECT-21K08907, KAKENHI-PROJECT-20K20479, KAKENHI-PROJECT-21K16635, KAKENHI-PROJECT-20KK0254, KAKENHI-PROJECT-20KK0255
  • [Journal Article] Lung Microvascular Niche, Repair, and Engineering.2020

    • Author(s)
      Tsuchiya T, Doi R, Obata T, Hatachi G, Nagayasu T.
    • Journal Title

      Front Bioeng Biotechnol.

      Volume: 8 Pages: 105-105

    • DOI

      10.3389/fbioe.2020.00105

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Journal Article] Regeneration of esophagus using a scaffold-free biomimetic structure created with bio-three-dimensional printing.2019

    • Author(s)
      Takeoka Y, Matsumoto K, Taniguchi D, Tsuchiya T, Machino R, Moriyama M, Oyama S, Tetsuo T, Taura Y, Takagi K, Yoshida T, Elgalad A, Matsuo N, Kunizaki M, Tobinaga S, Nonaka T, Hidaka S, Yamasaki N, Nakayama K, Nagayasu T.
    • Journal Title

      PLoS One.

      Volume: 14 Issue: 3 Pages: e0211339-e0211339

    • DOI

      10.1371/journal.pone.0211339

    • NAID

      120006987768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10595
  • [Journal Article] Human lung microvascular endothelial cells as potential alternatives to human umbilical vein endothelial cells in bio-3D-printed trachea-like structures.2019

    • Author(s)
      Taniguchi D, Matsumoto K, Machino R, Takeoka Y, Elgalad A, Taura Y, Oyama S, Tetsuo T, Moriyama M, Takagi K, Kunizaki M, Tsuchiya T, Miyazaki T, Hatachi G, Matsuo N, Nakayama K, Nagayasu T.
    • Journal Title

      TISSUE CELL

      Volume: 63 Pages: 101321-101321

    • DOI

      10.1016/j.tice.2019.101321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02895
  • [Journal Article] Replacement of Rat Tracheas by Layered, Trachea‐Like, Scaffold‐Free Structures of Human Cells Using a Bio‐3D Printing System2019

    • Author(s)
      Machino Ryusuke、Matsumoto Keitaro、Taniguchi Daisuke、Tsuchiya Tomoshi、Takeoka Yosuke、Taura Yasuaki、Moriyama Masaaki、Tetsuo Tomoyuki、Oyama Shosaburo、Takagi Katsunori、Miyazaki Takuro、Hatachi Go、Doi Ryoichiro、Shimoyama Koichiro、Matsuo Naoto、Yamasaki Naoya、Nakayama Koichi、Nagayasu Takeshi
    • Journal Title

      Advanced Healthcare Materials

      Volume: 8 Issue: 7 Pages: 1800983-1800983

    • DOI

      10.1002/adhm.201800983

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02895
  • [Journal Article] Adipose-derived mesenchymal stem cells attenuate rejection in a rat lung transplantation model2018

    • Author(s)
      Watanabe H, Tsuchiya T, Shimoyama K,Shimizu S,Akita S,Yukawa H, Baba Y, Nagayasu T
    • Journal Title

      Journal of Surgical Research

      Volume: 227 Pages: 17-27

    • DOI

      10.1016/j.jss.2018.01.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26790006, KAKENHI-PROJECT-15H04944, KAKENHI-PLANNED-17H06354
  • [Journal Article] 105.Sodium hydroxide based non-detergent decellularizing solution for rat lung.2018

    • Author(s)
      Sengyoku H, Tsuchiya T, Obata T, Doi R, Hashimoto Y, Ishii M, Sakai H, Matsuo N, Taniguchi D, Suematsu T, Lawn M, Matsumoto K, Miyazaki T, Nagayasu T
    • Journal Title

      Organogenesis

      Volume: 11 Issue: 2 Pages: 1-13

    • DOI

      10.1080/15476278.2018.1462432

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Journal Article] Sodium hydroxide based non-detergent decellularizing solution for rat lung2018

    • Author(s)
      Sengyoku H, Tsuchiya T, Obata T, Doi R, Hashimoto Y, Ishii M, Sakai H, Matsuo N, Taniguchi D, Suematsu T, Lawn M, Matsumoto K, Miyazaki T, Nagayasu T
    • Journal Title

      Organogenesis

      Volume: 14 Pages: 94-106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10686
  • [Journal Article] Transplantation of bioengineered rat lungs recellularized with endothelial and adipose-derived stromal cells2017

    • Author(s)
      Doi Ryoichiro, Tsuchiya Tomoshi, Mitsutake Norisato, Nishimura Satoshi, Matsuu-Matsuyama Mutsumi, Nakazawa Yuka, Ogi Tomoo, Akita Sadanori, Yukawa Hiroshi, Baba Yoshinobu, Yamasaki Naoya, Matsumoto Keitaro, Miyazaki Takuro, Kamohara Ryotaro, Hatachi Go, Sengyoku Hideyori et al.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41598-017-09115-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K00554, KAKENHI-PROJECT-15H05333, KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-15H04944, KAKENHI-PROJECT-17H01877
  • [Journal Article] Ventilation-Based Decellularization System of the Lung.2016

    • Author(s)
      Tsuchiya T, Mendez J, Calle EA, Hatachi G, Doi R, Zhao L, Suematsu T, Nagayasu T, Niklason LE.
    • Journal Title

      Biores Open Access.

      Volume: 5 Issue: 1 Pages: 118-126

    • DOI

      10.1089/biores.2016.0012

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670629
  • [Journal Article] Germline mutations causing familial lung cancer.2015

    • Author(s)
      Tomoshige K, Matsumoto K, Tsuchiya T, Oikawa M, Miyazaki T, Yamasaki N, Mishima H, Kinoshita A, Kubo T, Fukushima K, Yoshiura K, Nagayasu T
    • Journal Title

      J Hum Genet

      Volume: 60 Pages: 597-603

    • NAID

      40020621414

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462180
  • [Journal Article] Poly(ADP-ribose) Polymerase Inhibitor (PJ34) Reduces Pulmonary Ischemia-Reperfusion Injury in Rats2014

    • Author(s)
      Go Hatachi, Tomoshi Tsuchiya, Takuro Miyazaki, Keitaro Matsumoto, Naoya Yamasaki, Shingo Matsushima, Atsushi Nanashima, Yoshikazu Higami, and Takeshi Nagayasu
    • Journal Title

      Transplantation

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592066
  • [Journal Article] Clinical and molecular analysis of synchronous double lung cancers2012

    • Author(s)
      Junichi Arai, Tomoshi Tsuchiya, Masahiro Oikawa, Koji Mochinaga, Tomayoshi Hayashi, Koh-ichiro Yoshiura, Kazuhiro Tsukamoto, Naoya Yamasaki, Keitaro Matsumoto, Takuro Miyazaki, Takeshi Nagayasu
    • Journal Title

      Lung Cancer

      Volume: 77 Pages: 281-287

    • NAID

      120006985469

    • Data Source
      KAKENHI-PROJECT-23592068
  • [Patent] 血管内皮増殖因子を高発現する臍帯由来間葉系幹細胞の製造方法、および肺疾患治療用医薬組成物2023

    • Inventor(s)
      永安武, 土谷智史, 岩竹真弓, 住田吉慶
    • Industrial Property Rights Holder
      永安武, 土谷智史, 岩竹真弓, 住田吉慶
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23K08299
  • [Patent] 疾患モデル2020

    • Inventor(s)
      土谷智史 永安武 溝口直也
    • Industrial Property Rights Holder
      土谷智史 永安武 溝口直也
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Acquisition Date
      2024
    • Data Source
      KAKENHI-PROJECT-20KK0255
  • [Patent] 疾患モデル2020

    • Inventor(s)
      土谷智史、永安武、溝口聡
    • Industrial Property Rights Holder
      土谷智史、永安武、溝口聡
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K19609
  • [Patent] 疾患モデル2019

    • Inventor(s)
      土谷智史、永安武、溝口聡
    • Industrial Property Rights Holder
      土谷智史、永安武、溝口聡
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-014778
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17K19609
  • [Patent] 疾患モデル2019

    • Inventor(s)
      土谷智史ほか
    • Industrial Property Rights Holder
      土谷智史ほか
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17K19609
  • [Patent] 疾患モデル2018

    • Inventor(s)
      土谷智史ほか
    • Industrial Property Rights Holder
      土谷智史ほか
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Patent] 脱細胞化用界面活性剤2018

    • Inventor(s)
      土谷智史ほか
    • Industrial Property Rights Holder
      土谷智史ほか
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] 超低流量肺灌流によるマウス脱細胞化手法のシステム開発2024

    • Author(s)
      丸山圭三郎、土肥良一郎、吉元崇文、土谷智史、松本桂太郎
    • Organizer
      第23回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K27613
  • [Presentation] Novel Designer Umbilical Cord-Derived Mesenchymal Stem Cells for COPD Treatment2023

    • Author(s)
      M.Iwatake, T.Tsuchiya, Y.Tanoue, S.Mizoguchi, K.Matsumoto, T.Nagayasu
    • Organizer
      ATS International Conference Committee
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K08299
  • [Presentation] Immunosuppressive Effects of Mesenchymal Stem Cells and the Timing of Their Use in a Rat Lung Transplantation Model2023

    • Author(s)
      Y.Tanoue, T.Tsuchiya, M.Iwatake, S.Mizoguchi, K.Matsumoto, T.Nagayasu
    • Organizer
      ATS International Conference Committee
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08977
  • [Presentation] 臓器骨格を使用した呼吸器系再生研究における細胞外マトリックスの重要性2023

    • Author(s)
      土谷智史
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] 肺移植での細胞治療と臓器再生2023

    • Author(s)
      土谷 智史、田上 幸憲、土肥 良一郎、岩竹 真弓、下山 考一郎、渡邉 洋之助、湯川 博、永安 武
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-22K08977
  • [Presentation] 超低流量肺灌流によるマウス脱細胞化手法のシステム開発2023

    • Author(s)
      丸山圭三郎、土肥良一郎、吉元崇文、土谷智史、松本桂太郎
    • Organizer
      第23回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-22K08978
  • [Presentation] 肺細胞治移植での療と臓器再生2023

    • Author(s)
      土谷智史
    • Organizer
      第22回再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-20KK0255
  • [Presentation] 臓器骨格を使用した呼吸器系再生研究 における細胞外マトリックスの重要性2023

    • Author(s)
      土谷智史
    • Organizer
      第22回再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-20KK0255
  • [Presentation] ラット肺移植モデルにおける免疫抑制を目的とした間葉系幹細胞治療の投与タイミングの検討2023

    • Author(s)
      田上 幸憲、土谷 智史、岩竹 真弓、宮﨑 拓郎、渡邉 洋之助、佐藤 和秀、湯川 博、畑地 豪、下山 孝一郎、松本 桂太郎、 朝重 耕一、土肥 良一郎、永安 武
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-22K08977
  • [Presentation] 臓器骨格を使用した呼吸器系再生研究における細胞外マトリックスの重要性2023

    • Author(s)
      土谷 智史、土肥 良一郎、岩竹 真弓、橋本 泰匡、湯川 博、永安 武
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-22K08977
  • [Presentation] ラットアロ肺移植モデルにおける移植前後の脂肪由来間葉系幹細胞投与とT -reg 細胞の動態2022

    • Author(s)
      土谷 智史、田上 幸憲 、下山 孝一郎、渡邉 洋之助、岩竹 真弓、宮崎 拓郎、湯川 博、永安 武
    • Organizer
      第48回日本臓器保存生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K08977
  • [Presentation] 脱細胞臓器骨格を用いた臓器再生・置換技術の成果と研究モデルへの展開2022

    • Author(s)
      土谷智史
    • Organizer
      第122 回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] 臓器骨格を用いた肺再生の中での 間葉系幹細胞の役割と今後の展望2022

    • Author(s)
      土谷智史
    • Organizer
      第21回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] ラット肺移植モデルを用いた脂肪由来間葉系幹細胞の投与タイミングの違いによる免疫抑制効果の検討2022

    • Author(s)
      田上幸憲、土谷智史、岩竹真弓、吉元崇文、中司交明、高村祐磨、松本桂太郎、宮﨑拓郎、朝重耕一、土肥良一郎、永安武
    • Organizer
      第38回 日本肺および心肺移植研究会
    • Data Source
      KAKENHI-PROJECT-19K09309
  • [Presentation] 脱細胞化、再細胞化技術を使った肺再生研究2022

    • Author(s)
      土谷智史
    • Organizer
      第75回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] ラット肺移植モデルを用いた脂肪由来間葉系幹細胞の投与タイミングの違いによる免疫抑制効果の検討2021

    • Author(s)
      田上幸憲、土谷智史、岩竹真弓、吉元崇文、中司交明、高村祐磨、松本桂太郎、宮﨑拓郎、朝重耕一、土肥良一郎、永安武
    • Organizer
      第47回 日本臓器保存生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09309
  • [Presentation] 肺再生研究の現状と展開 ‐臓器構造を再現する過程で見えてきた課題‐2021

    • Author(s)
      土谷智史
    • Organizer
      第121回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] 臓器骨格を利用した肺のOrgan engineering2021

    • Author(s)
      土谷智史
    • Organizer
      第61回日本呼吸器学会総会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] 臓器再生研究と外科医の役割2020

    • Author(s)
      土谷智史
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] 細胞置換技術を利用した肺再生 -細胞外マトリックスに関わる研究2019

    • Author(s)
      土谷 智史、松本 桂太郎、宮崎 拓郎、畑地 豪、土肥 良一郎、渡邉 洋之助、谷口 大輔、永安 武
    • Organizer
      第36回呼吸器外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10686
  • [Presentation] 自己脂肪由来間葉系幹細胞による免疫抑制効果を目的とした、ラット肺移植モデルにおける細胞治療の試み2019

    • Author(s)
      土谷 智史
    • Organizer
      第119回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] Transwell共培養システムを用いた脂肪組織由来間葉系幹細胞による肺細胞間バリア機能増強効果の解析2019

    • Author(s)
      石井 光寿、土谷 智史、土肥 良一郎、溝口 聡 、松本 桂太郎、畑地 豪、渡邉 洋之助、永安 武
    • Organizer
      日本肺サーファクタント・界面医学会
    • Data Source
      KAKENHI-PROJECT-19H03747
  • [Presentation] 細胞置換技術を利用した 肺再生 -細胞外マトリックスに関わる研究-2019

    • Author(s)
      土谷智史
    • Organizer
      第36回日本呼吸器外科学会
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] 小型再生肺でのex vivo肺癌モデル作製の試み2019

    • Author(s)
      土谷智史
    • Organizer
      第46回日本臓器保存生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19609
  • [Presentation] Application of decellularized organ scaffolds for respiratory tissue engineering2018

    • Author(s)
      土谷 智史
    • Organizer
      第54回日本肺サーファクタント・界面医学会学術研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] Potential of Adipose-Derived Stem/Stromal Cells for Lung Transplantation and Lung Tissue Engineering2018

    • Author(s)
      土谷智史
    • Organizer
      American Thoracic Society 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] Remodeling the vasculature in the decellularized lung scaffold using adipogenic stromal cells2018

    • Author(s)
      Tomoshi Tsuchiya
    • Organizer
      5th TERMIS World Congress 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] Potential of Adipose-Derived Stem/Stromal Cells for Lung Transplantation and Lung Tissue Engineering2018

    • Author(s)
      Tomoshi Tsuchiya
    • Organizer
      American Thoracic Society 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] Remodeling the vasculature in the decellularized lung scaffold using adipogenic stromal cells2018

    • Author(s)
      土谷智史
    • Organizer
      第5回国際組織工学・再生医療学会 世界会議2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] 3次元構築を保った肺再生の取り組みとヒト肺創出への道2018

    • Author(s)
      土谷 智史
    • Organizer
      第17回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] 3次元構築を保った肺再生の取り組みとヒト肺創出への道2018

    • Author(s)
      土谷智史
    • Organizer
      第17回再生医療学会
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] 脱細胞組織骨格を利用した肺の再生法とその問題点2017

    • Author(s)
      土谷智史
    • Organizer
      第40回呼吸器内視鏡学会
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] 臓器再生第一段階としての肺-脱細胞化組織骨格内の血管網の構築2016

    • Author(s)
      土谷智史
    • Organizer
      第43回日本臓器保存学会
    • Place of Presentation
      東京薬科大学(東京都八王子市)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-26670629
  • [Presentation] 臓器再生第一段階としての肺-脱細胞化組織骨格内の血管網の構築2016

    • Author(s)
      土谷智史
    • Organizer
      第43回日本臓器保存生物医学会学術集会
    • Place of Presentation
      東京薬科大学 (東京都八王子市)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-15H04944
  • [Presentation] 非小細胞肺癌にpけるEGR変異とDPDおよびその関連因子に関する検討2015

    • Author(s)
      富永哲郎,土谷智史,朝重耕一,畑地 豪,荒井淳一,宮﨑拓郎,松本桂太郎,山崎直哉,永安 武
    • Organizer
      日本臨床分子形態学会
    • Place of Presentation
      長崎大学(長崎県長崎市)
    • Year and Date
      2015-09-19
    • Data Source
      KAKENHI-PROJECT-26462130
  • [Presentation] 間歇的圧変化を利用した、気管からのラット肺脱細胞化法2015

    • Author(s)
      土谷智史
    • Organizer
      第51回日本移植学会総会
    • Place of Presentation
      ホテル日航熊本(熊本県・熊本市)
    • Year and Date
      2015-10-01
    • Data Source
      KAKENHI-PROJECT-26670629
  • [Presentation] 同時多発肺腫瘍のarray-comparative-genomic-hybridization(aCG H)を用いた細胞遺伝学的検索と予後解析2012

    • Author(s)
      荒井淳一、及川将弘、土谷智史、宮崎拓郎、松本桂太郎、山崎直哉、林徳眞吉、吉浦孝一郎、永安武
    • Organizer
      第29回日本呼吸器外科学会
    • Place of Presentation
      秋田キャッスルホテル
    • Year and Date
      2012-05-18
    • Data Source
      KAKENHI-PROJECT-23592068
  • [Presentation] 次世代シーケンサーを用いたエキソーム解析による家族性肺癌責任遺伝子の同定

    • Author(s)
      朝重耕一、宮崎拓郎、松本桂太郎、土谷智史、山崎直哉、永安武
    • Organizer
      第113回 日本外科学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Data Source
      KAKENHI-PROJECT-25462180
  • [Presentation] NaOH-PBS によるラット肺の脱細胞化・再細胞化

    • Author(s)
      扇玉秀順, 土谷智史, 山崎直哉, 松本桂太郎, 宮﨑拓郎, 永安武
    • Organizer
      第41回日本臓器保存生物医学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府)
    • Year and Date
      2014-11-28 – 2014-11-29
    • Data Source
      KAKENHI-PROJECT-26670629
  • 1.  NAGAYASU Takeshi (80284686)
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