SAHARA Hisashi 佐原寿史

Researcher Number	90452333
Other IDs
External Links
Affiliation (Current)	2022: 鹿児島大学, 総合科学域共同学系, 准教授
Affiliation (based on the past Project Information) *help	2022: 鹿児島大学, 総合科学域共同学系, 准教授 2018 – 2021: 鹿児島大学, 総合科学域総合研究学系, 准教授 2014 – 2017: 鹿児島大学, 学内共同利用施設等, 准教授 2013 – 2017: 鹿児島大学, 医用ミニブタ・先端医療開発研究センター, 准教授 2015 – 2016: 鹿児島大学, 医用ミニブタ・先端医療開発研究センター臓器置換・異種移植外科分野, 准教授 … More 2012 – 2013: 鹿児島大学, 医用ミニブタ・先端医療開発研究センター, 特任准教授 2010 – 2011: Kagoshima University, フロンティアサイエンス研究推進センター, 特任准教授 2010: 京都大学, フロンティアサイエンス研究推進センター, 特任准教授 2007 – 2009: Kyoto University, 医学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Thoracic surgery / Respiratory surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55040:Respiratory surgery-related Except Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 56030:Urology-related / Basic Section 55040:Respiratory surgery-related / Urology / Prosthodontics/ Dental materials science and / Basic Section 38050:Food sciences-related / Basic Section 57050:Prosthodontics-related
Keywords	Principal Investigator 肺移植 / 移植・再生医療 / ミニブタ / 虚血再灌流障害 / 一酸化炭素 / トランスレーショナルリサーチ / 異種肺移植 / 異種移植 / 慢性拒絶 / 前臨床実験 … More / 臓器保存 / 前臨床研究 / 自然免疫 / ブタ / 拒絶反応 / 心停止ドナー / 急性拒絶 / MHC / GalT-KOブタ / カニクイザル / 急性期肺機能不全 / Ex-vivo灌流 / CalT-KOブタ / 血小板 / 肺血管抵抗 / 間葉系幹細胞 / 脳死 / 臓器保護 / 脳死ドナー / 高圧 / 非凍結 / クラウン系ミニブタ / 霊長類 / CD47 / マクロファージ / アデノシンA2A受容体 / 免疫寛容 / 外科 / 肺胞マクロファージ / トランスレーショナル研究 / 誘導性気管支関連リンパ節 / 加齢 / 大動物 / 国際共同研究 / 遺伝子改変動物 / 免疫寛容誘導 / 異種腎移植 / 遺伝子改変ブタ … More Except Principal Investigator ミニブタ / 移植・再生医療 / 腎移植 / 虚血再灌流障害 / 前臨床実験 / トランスレーショナルリサーチ / 免疫寛容 / 前臨床研究 / マージナルドナー / 臓器保護 / トランスレーショナル研究 / キメラ / 一酸化炭素 / 大動物 / 再生医療 / 再生医学 / 胸腺 / 移植外科学 / 膵島移植 / 膵島・腎移植 / 小腸移植 / 肺移植 / 心移植 / 常温腎臓持続体外灌流保存 / 硫化水素 / 臓器灌流保存 / MHC / 間葉系幹細胞 / 骨再生 / 肺胞バリア機能 / アルゴン / 若年化再生 / テストステロン / 制御性 T 細胞 / 制御性T細胞 / 移植免疫寛容 / HGF / 末梢性免疫寛容 / マクロファージ / CFSE-MLR / 移植後免疫寛容 / 血管再構築 / 組織適合性抗原 / GvH / GvHR / キメリズム / 主要組織適合性抗原 / サイトカイン / 腸間膜リンパ節 / 抗HMGB1抗体 / 高圧 / 臓器保存 / 移植・再生 / 虚血再潅流障害 / 移植再生医療 / HMGB1 / 腎臓体外灌流保存 / 腎臓移植 / 骨髄移植 / サル / 外科 / カニクイザル / 移植免疫 / 虚血再還流障害 / i移植免疫 / 常温灌流保存 / 虚血再灌流傷害 / 温虚血 / 浸漬冷却保存 / 移植心冠動脈病変 / 加齢 / 自然免疫 / 動脈硬化 / ヒトアポリポ蛋白(a) / 動脈硬化モデルミニブタ / 動脈硬化促進遺伝子導入MHC確立ミニブタ / 灌流保存 / 骨増生 / クラウン系ミニブタ / 体外循環 / 移植片対宿主反応 / 肺再生 / 生理劇刺激 / 移植 / バイオリアクター / 医工学 / 脱細胞化 / 再細胞化 / 接着因子 / バリア機能 / 生理的刺激 / 血管ニッチ / 幹細胞 / 組織骨格 / 臓器工学 / 血管 / ニッチ / 肺胞上皮 / 血管内皮 / 桜島大根 / トリゴネリン / 血管内皮機能 / 一酸化窒素 / 予防 / 臓器移植 / 異種移植 / 脱細胞 / 脂肪幹細胞 / 免疫抑制治療 / 拒絶抑制 / 気管移植 / 希ガス / 脳死 / 心停止ドナー / 分子マーカー / 3次リンパ組織 / 慢性移植腎障害 / 脂肪由来間葉系幹細胞 / 急性肺障害/急性呼吸窮迫症候群 Less

ミニブタを用いた移植腎内3次リンパ組織形成と慢性移植腎障害進展機序の解明
- Principal Investigator
  
  関島光裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kagoshima University
マージナルドナー腎移植成績向上を目指した酸素供給下持続低温灌流法の探索
- Principal Investigator
  
  日下守
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fujita Health University
脂肪幹細胞による肺胞バリア機能強化とALI/ARDSへの新たな細胞治療の基礎研究
- Principal Investigator
  
  石井光寿
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
加齢グラフト内誘導性気管支関連リンパ節の形成過程と大動物移植肺拒絶への関与の解明Principal Investigator
- Principal Investigator
  
  佐原寿史
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kagoshima University
国際研究ネットワークの構築に基づく異種移植実用化戦略の確立Principal Investigator
- Principal Investigator
  
  佐原寿史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kagoshima University
Stimulation of nitric oxide (NO) production in vascular endothelial cells by Raphanus sativus (Sakurajima Daikon) extracts
- Principal Investigator
  
  加治屋勝子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Kagoshima University
アルゴンによる移植腎保護効果と至適投与法の前臨床ミニブタ実験による解明
- Principal Investigator
  
  昇修治
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto Prefectural University of Medicine
脱細胞・再細胞による再生医療と異種移植によるハイブリッド気道移植モデルの開発
- Principal Investigator
  
  渡邉洋之助
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Nagasaki University
前臨床大動物モデルによる希ガスを用いた新規移植肺保護戦略の確立
- Principal Investigator
  
  岩永健裕
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
ガス状シグナル物質の複合的投与による移植腎保護効果と機序の解明をはかる前臨床実験
- Principal Investigator
  
  有吉勇一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
Fundamental research for realizing regenerative medicine using jaw bone marrow mesenchymal stem cells
- Principal Investigator
  
  西村正宏
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Kagoshima University
Preclinical study on organ preconditioning before transplantation for marginal grafts
- Principal Investigator
  
  Kusaka Mamoru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fujita Health University
前臨床モデルでの移植片対宿主反応（LGVHR）に基づく革新的小腸移植免疫寛容誘導
- Principal Investigator
  
  山田和彦
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kagoshima University
組織骨格を利用した再生臓器におけるハイブリッド型血管ニッチの確立と移植研究
- Principal Investigator
  
  土谷智史
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
自然・獲得免疫系を繋ぐ肺胞マクロファージの機序解明による同種・異種肺移植成績向上Principal Investigator
- Principal Investigator
  
  佐原寿史
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
Mechanism of development of cardiac allograft vasculopathy following heart transplantation using genetically engineered MHC-defined miniature swine.
- Principal Investigator
  
  SEKIJIMA Mitsuhiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kagoshima University
Development of protection and repair of preserved organs using small interfering RNA (siRNA) in large animal model .
- Principal Investigator
  
  Nobori Shuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Normothermic machine perfusion of the kidney to evaluate the donor organ before transplantation: Preclinical large animal study using MHC-defined CLAWN miniature swine
- Principal Investigator
  
  ARIYOSHI Yuichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Multiple control and visualization of self-somatic- stem cells for atrophic jaw bone augmentation
- Principal Investigator
  
  NISHIMURA Masahiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Kagoshima University
Establish a treatment strategy to diabetic nephropathy using combined kidney and islets transplantation
- Principal Investigator
  
  YAMADA Kazuhiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kagoshima University
Modulation of inflammation and innate immune responses subsequent to endothelial cell damage in lung allo and xenotransplantationPrincipal Investigator
- Principal Investigator
  
  SAHARA Hisashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kagoshima University
Establishment of hydrogen sulfide therapy against renal ischemia-reperfusion injury using large animal to attempt to increase the donor organ pool
- Principal Investigator
  
  SEKIJIMA Mitsuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kagoshima University
Induction of tolerance by rejuvenation of thymus in preclinical large animal model.
- Principal Investigator
  
  Nobori Shuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Preclinical study on protection strategy and function recovery strategy of preimplantation for marginal graft
- Principal Investigator
  
  Kusaka Mamoru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Fujita Health University
Establishment of novel lung preservation method in a stable unfrozen state under high pressurized conditionPrincipal Investigator
- Principal Investigator
  
  SAHARA HISASHI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Kagoshima University
Effects of carbon monoxide inhalation on allograft survival of the lung or kidney from brain death donors in miniature swine.
- Principal Investigator
  
  HIRAKARA Atsushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nippon Medical School
New organ preservation method under pressurized, non-frozen condition: Preclinical study using CLAWN miniature swine
- Principal Investigator
  
  YAMADA Kazuhiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kagoshima University
Establishment of a new strategy to improve graft function after lung transplantation from brain-dead donors using mesenchymal stem cells - preclinical study using MHC-inbred CLAWN miniature swinePrincipal Investigator
- Principal Investigator
  
  SAHARA Hisashi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Kagoshima University
Intestinal Transplantation in CLAWN Miniature Swine: Establishment of Orthotopic Model and Roles of Chimerisms, HVG and GVH Responses
- Principal Investigator
  
  YAMADA Kazuhiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kagoshima University
Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantationPrincipal Investigator
- Principal Investigator
  
  SAHARA Hisashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kagoshima University
Attempt to induce tolerance of kidneys by pharmacologic rejuvenation of thymus in miniature swine
- Principal Investigator
  
  NOBORI Shuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
前臨床ミニブタ同種腎移植モデルを用いたHGFによる免疫寛容誘導および機序の解明
- Principal Investigator
  
  OKU Manei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kagoshima University
Role of prevascularization of islets in the induction of tolerance of allogeneic islets in miniature swine
- Principal Investigator
  
  HIRAKATA Atsushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nippon Medical School
Beneficial Effects of Inhalation of Carbon Monoxide on Pulmonary Allograft Survival in MHC-inbred CLAWN Miniature Swine.Principal Investigator
- Principal Investigator
  
  SAHARA Hisashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kagoshima University
  Kyoto University
Control of ischemia-reperfusion injury and chronic allograft rejection of lung by inhaled carbon monoxide in miniature swinePrincipal Investigator
- Principal Investigator
  
  SAHARA Hisashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University

[Journal Article] Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival.2020
- Author(s)
  Watanabe H, Ariyoshi Y, Pomposelli T, Takeuchi K, Ekanayake-Alper DK, Boyd LK, Arn SJ, Sahara H, Shimizu A, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K.
- Journal Title
  
  Xenotransplantation
  
  Volume: 27
- DOI
  10.1111/xen.12552
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09722, KAKENHI-PROJECT-19H03748
[Journal Article] Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine.2019
- Author(s)
  Sekijima M, Sahara H, Shimizu A, Iwanaga T, Murokawa T, Ariyoshi Y, Pomposelli T, Khosravi Maharlooei M, Sykes M, Yamada K.
- Journal Title
  
  Xenotransplantation.
  
  Volume: 26
- DOI
  10.1111/xen.12543
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09722
[Journal Article] GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels2018
- Author(s)
  Watanabe H、Sahara H、Nomura S、Tanabe T、Yamada Kazuhiko et al.
- Journal Title
  
  Xenotransplantation
  
  Volume: 印刷中
- DOI
  10.1111/xen.12391
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05432
[Journal Article] Lung xenotransplantation2017
- Author(s)
  Sahara Hisashi、Watanabe Hironosuke、Pomposelli Thomas、Yamada Kazuhiko
- Journal Title
  
  Current Opinion in Organ Transplantation
  
  Volume: 22 Pages: 541-548
- DOI
  10.1097/mot.0000000000000465
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05432
[Journal Article] Hydrogen sulfide prevents renal ischemia-reperfusion injury in CLAWN miniature swine2017
- Author(s)
  Sekijima Mitsuhiro、Sahara Hisashi、Miki Katsuyuki、Villani Vincenzo、Ariyoshi Yuichi、Iwanaga Takehiro、Tomita Yusuke、Yamada Kazuhiko
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 219 Pages: 165-172
- DOI
  10.1016/j.jss.2017.05.123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10032
[Journal Article] Effects of carbon monoxide on early dysfunction and microangiopathy following GalT-KO porcine pulmonary xenotransplantation in cynomolgus monkeys2017
- Author(s)
  Sahara Hisashi、Sekijima Mitsuhiro、Ariyoshi Yuichi、Kawai Akihiro、Miura Kohei、Waki Shiori、Nathan Louras、Tomita Yusuke、Iwanaga Takehiro、Nakano Kazuaki、Matsunari Hitomi、Date Hiroshi、Nagashima Hiroshi、Shimizu Akira、Yamada Kazuhiko
- Journal Title
  
  Xenotransplantation
  
  Volume: 25
- DOI
  10.1111/xen.12359
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05432
[Journal Article] 特集「毒ガス？いいえ治療薬です」．【新たな治療薬としての一酸化炭素への期待】2016
- Author(s)
  佐原寿史, 関島光裕, 山田和彦
- Journal Title
  
  臨床麻酔
  
  Volume: 39(6) Pages: 855-864
- Data Source
  KAKENHI-PROJECT-26293355
[Journal Article] 特集「毒ガス？いいえ治療薬です」．【新たな治療薬としての一酸化炭素への期待】．2015
- Author(s)
  佐原寿史, 関島光裕, 山田和彦
- Journal Title
  
  臨床麻酔
  
  Volume: 39(6) Pages: 855-864
- Data Source
  KAKENHI-PROJECT-26293355
[Journal Article] 特集「毒ガス？いいえ治療薬です」．【新たな治療薬としての一酸化炭素への期待】2015
- Author(s)
  佐原寿史, 関島光裕, 山田和彦
- Journal Title
  
  臨床麻酔
  
  Volume: 6 Pages: 855-864
- Data Source
  KAKENHI-PROJECT-25461965
[Journal Article] Protective effect of neutralization of the extracellular high-mobility group box-1 on renal ischemia-reperfusion injury in miniature swine.2014
- Author(s)
  Miura K, Sahara H, Sekijima M, Kawai A, Waki S, Nishimura H, Setoyama K, Clayman ES, Shimizu A, Yamada K.
- Journal Title
  
  Transplantation
  
  Volume: Nov 15;98(9) Pages: 937-943
- DOI
  10.1097/tp.0000000000000358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461965, KAKENHI-PROJECT-26293355
[Journal Article] Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates.2013
- Author(s)
  Okumi M, Scalea JR, Gillon BC, Tasaki M, Villani V, Cormack T, Hirakata A, Shimizu A, Sachs DH, Yamada K.
- Journal Title
  
  Xenotransplantation
  
  Volume: 13 Pages: 1193-1202
- DOI
  10.1111/ajt.12194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591417, KAKENHI-PROJECT-23390337
[Journal Article] 大動物を用いた前臨床虚血再灌流障害モデルの作製とマージナルドナー活用戦略2013
- Author(s)
  山田和彦, 佐原寿史
- Journal Title
  
  Organ Biology
  
  Volume: 20 Pages: 42-50
- Data Source
  KAKENHI-PROJECT-25461965
[Journal Article] Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates2013
- Author(s)
  Shimatsu Y, Yamada K, Horii W, Hirakata A, Sakamoto Y, Waki S, Sano J, Saitoh T, Sahara H, Shimizu A, Yazawa H, Sachs DH, Nunoya T
- Journal Title
  
  Xenotransplantation
  
  Volume: 20(3) Pages: 157-64
- DOI
  10.1111/xen.12031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390337
[Journal Article] Hepatocyte growth factor sustains tregs and prolongs the survival of kidney allografts in MHC-inbred CLAWN-miniature swine. Transplantation. 2012 Jan 27 ; 93(2) : 148-552012
- Author(s)
  Oku M, et al.
- Journal Title
  
  Transplantation
  
  Volume: 93 Pages: 148-155
- DOI
  10.1097/tp.0b013e31823be83f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742, KAKENHI-PROJECT-22591411
[Journal Article] ドナーに対する一酸化炭素吸入療法による移植肺生着延長効果：前臨床ミニブタモデルを用いた新たな臓器保存方法への発展2012
- Author(s)
  佐原寿史、山田和彦
- Journal Title
  
  Organ Biology
  
  Volume: 19 Pages: 11-14
- NAID
  130004710024
- Data Source
  KAKENHI-PROJECT-23390337
[Journal Article] ドナー臓器の機能評価および修復を可能とする常温体外肺循環回路（EVLP）下での一酸化炭素吸入療法によるミニブタ移植肺生着延長効果の検討2012
- Author(s)
  佐原寿史、脇詩織、関島光裕、三浦宏平、河合昭浩、清水章、山田和彦
- Journal Title
  
  今日の移植
  
  Volume: 25 Pages: 495-499
- Data Source
  KAKENHI-PROJECT-23390337
[Journal Article] 異種臓器移植の臨床応用をめざして-前臨床異種移植はここまで進んでいる2011
- Author(s)
  山田和彦、佐原寿史
- Journal Title
  
  医学のあゆみ
  
  Volume: 237(5) Pages: 559-566
- Data Source
  KAKENHI-PROJECT-23390337
[Journal Article] 異種臓器移植の臨床応用をめざして-前臨床異種移植はここまで進んでいる2011
- Author(s)
  山田和彦, 佐原寿史
- Journal Title
  
  医学のあゆみ
  
  Volume: 237(5) Pages: 559-66
- URL
  http://www.ishiyaku.co.jp/magazines/ayumi/AyumiArticleDetail.aspx?BC=286290&AC=10269
- Data Source
  KAKENHI-PROJECT-23390337
[Journal Article] Autoimmune sensitization to cardiac myosin leads to acute rejection of cardiac allografts in miniature swine2011
- Author(s)
  Veillette GR, Sahara H, Meltzer AJ, Weiss MJ, Iwamoto y Kim KM, Rosengard BR, Allan JS, Houser SL, Sachs DH, Benichou G, Madsen JC
- Journal Title
  
  Transplantation
  
  Volume: 91(11) Pages: 1187-1191
- DOI
  10.1097/tp.0b013e318218415d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390337
[Journal Article] Beneficial Effects of Perioperative Low-dose Inhalation of Carbon Monoxide on Pulmonary Allograft Survival in MHC-inbred CLAWN Miniature Swine.2010
- Author(s)
  Sahara H, Shimizu A, Oku M, et al.
- Journal Title
  
  Transplantation
  
  Volume: 90(12) Pages: 1336-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591411
[Journal Article] Beneficial Effects of Perioperative Low-dose Inhalation of Carbon Monoxide on Pulmonary Allograft Survival in MHC-inbred CLAWN Miniature Swine.2010
- Author(s)
  Sahara H, Shimizu A, Setoyama K, Oku M, Okumi M, Nishimura H, Oriyanhan W, Tasaki M, Scalea J, Wada H, Bando T, Date H, Yamada K
- Journal Title
  
  Transplantation
  
  Volume: 90(12) Pages: 1336-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791322
[Journal Article] Reduces Pulmonary Ischemia-Reperfusion Injury in Miniature Swine2010
- Author(s)
  Sahara H, Shimizu A, Setoyama K, Okumi M, Oku M, Samelson-Jones E, Yamada K, Carbon Monoxide
- Journal Title
  
  J Thorac Cardiovasc Surg Vol.139, No.6
  
  Pages: 1594-1601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791322
[Journal Article] Beneficial Effects of Perioperative Low-dose Inhalation of Carbon Monoxide on Pulmonary Allograft Survival in MHC-inbred CLAWN Miniature Swine2010
- Author(s)
  Sahara H, Shimizu A, Setoyama K, Oku M, Okumi M, Nishimura H, Oriyanhan W, Tasaki M, Scalea J, Wada H, Bando T, Date H, Yamada K
- Journal Title
  
  Transplantation Vol.90, No.12
  
  Pages: 1336-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791322
[Journal Article] Carbon Monoxide Reduces Pulmonary Ischemia-Reperfusion Injury in Miniature Swine.2010
- Author(s)
  Sahara H, Shimizu A, Setoyama K, Okumi M, Oku M, Samelson-Jones E, Yamada K
- Journal Title
  
  J Thorac Cardiovasc Surg.
  
  Volume: 139(6) Pages: 1594-1601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791322
[Journal Article] Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine.2009
- Author(s)
  Sahara H, Shimizu A, Setoyama K, Okumi M, Oku M, Samelson-Jones E, Yamada K.
- Journal Title
  
  Journal of Thoracic and Cardiovascular Surgery 2009 Nov 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791322
[Journal Article] The indirect alloresponse impairs the induction but not maintenance of tolerance to MHC class I-disparate allografts.2009
- Author(s)
  Weiss MJ, Guenther DA, Mezrich JD, Sahara H, Ng CY, Meltzer AJ, Sayre JK, Cochrane ME, Pujara AC, Houser SL, Sachs DH, Rosengard BR, Allan JS, Benichou G, Madsen JC.
- Journal Title
  
  American journal of transplantation 9(1)
  
  Pages: 105-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Journal Article] The indirect alloresponse impairs the induction but not maintenance of tolerance to MHC class I-disparate allografts2009
- Author(s)
  Weiss MJ, Guenther DA, Mezrich JD, Sahara H, Ng CY, Meltzer AJ, Sayre JK, Cochrane ME, Pujara AC, Houser SL, Sachs DH, Rosengard BR, Allan JS, Benichou G, Madsen JC
- Journal Title
  
  American Journal of Transplantation 9
  
  Pages: 105-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Journal Article] Repetitive gastric aspiration leads to augmented indirect allorecognition after lung transplantation in miniature swine.2008
- Author(s)
  Meltzer AJ, Weiss MJ, Veillette GR, Sahara H, Ng CY, Cochrane ME, Houser SL, Sachs DH, Rosengard BR, Madsen JC, Wain JC, Allan JS.
- Journal Title
  
  Transplantation 86 (12)
  
  Pages: 1824-1829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Journal Article] Repetitive gastric aspiration leads to augmented indirect allorecognition after lung transplantation in miniature swine2008
- Author(s)
  Meltzer AJ, Weiss MJ, Veillette GR, Sahara H, Ng CY, Cochrane ME, Houser SL, Sachs DH, Rosengard BR, Madsen JC, Wain JC, Allan JS
- Journal Title
  
  Transplantation 86
  
  Pages: 1824-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Journal Article] Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays.2008
- Author(s)
  Oku M, Okumi M, Sahara H, Hirakata A, Onoe T, Griesemer AD, Yamada K.
- Journal Title
  
  Transplant immunology 20 (1-2)
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Journal Article] Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays2008
- Author(s)
  Oku M, Okumi M, Sahara H, Hirakata A, Onoe T, Griesemer AD, Yamada K.
- Journal Title
  
  Transplant Immunology 20
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Journal Article] Operational tolerance to class I disparate lungs can be induced despite pretransplant immunization with class I allopeptides2007
- Author(s)
  Shoji T, Sahara H, Muniappan A, Guenther DA, Wain JC, Houser SL, Bravard MA, Pujara AC, Hasse RS, Sachs DH, Madsen JC, Allan JS
- Journal Title
  
  Transplantation 84
  
  Pages: 1467-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Journal Article] Operational tolerance to class I disparate lungs can be induced despite pretransplant immunization with class I allopeptides.2007
- Author(s)
  Shoji T, Sahara H, Muniappan A, Guenther DA, Wain JC, Houser SL, Bravard MA, Pujara AC, Hasse RS, Sachs DH, Madsen
- Journal Title
  
  Transplantation 84(11)
  
  Pages: 1467-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] クラウン系ミニブタを用いたアルゴン吸入による肺虚血再灌流障害軽減効果2021
- Author(s)
  岩永健裕、関島光裕、市成ゆりか、清水章、佐原寿史
- Organizer
  第68回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20K09169
[Presentation] 高度温虚血腎移植に対する22℃臓器保存の有効性－MHC確立クラウン系ミニブタを用いた体外機械灌流および腎移植モデルによる評価.2021
- Author(s)
  有吉勇一, 関島光裕, 河合彰浩, 岩永健裕,市成ゆりか, 清水　章, 日下　守, 山田和彦, 佐原寿史
- Organizer
  第47回日本臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09722
[Presentation] パネルディスカッション 2 「肺移植における予後改善に向けての取組」「異種肺移植の成績向上を目指した前臨床実験の展望」2021
- Author(s)
  佐原寿史, 関島光裕, 岩永健裕, 市成ゆりか, 清水章
- Organizer
  第38回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-19H03748
[Presentation] クラウン系ミニブタ用いたアルゴン吸入による肺虚血再灌流障害軽減効果2021
- Author(s)
  岩永健裕, 関島光裕, 市成ゆりか, 清水章, 佐原寿史
- Organizer
  第68回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20K09169
[Presentation] 肺虚血再灌流障害に対するアルゴン吸入の治療効果－クラウン系ミニブタを用いた検討2021
- Author(s)
  岩永健裕, 佐原寿史, 関島光裕, 市成ゆりか, 清水章
- Organizer
  第47回日本臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09169
[Presentation] クラウン系ミニブタを用いた希ガス吸入による肺虚血再灌流障害抑制効果の評価2021
- Author(s)
  佐原寿史, 岩永健裕, 関島光裕, 市成ゆりか, 清水章
- Organizer
  第74回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09169
[Presentation] 分野別シンポジウム9「肺移植におけるドナー不足にどう取組むか」「ドナー臓器不足克服のための異種肺移植研究の現状と課題」2021
- Author(s)
  佐原寿史, 関島光裕, 岩永健裕. 市成ゆりか, 渡邉洋之助, 清水章
- Organizer
  第57回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-19H03748
[Presentation] アルゴンガス吸入によるミニブタ肺虚血再灌流障害抑制効果2021
- Author(s)
  岩永健裕, 佐原寿史, 関島光裕, 市成ゆりか, 清水章
- Organizer
  第38回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09169
[Presentation] 前臨床異種肺移植研究の現状と課題2020
- Author(s)
  佐原寿史
- Organizer
  第22回日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-19H03748
[Presentation] 異種肺移植成績向上を目指した挑戦～日米における前臨床異種移植実験から見えてきた課題2019
- Author(s)
  佐原寿史
- Organizer
  第35回日本肺および心肺移植研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] Effects of static subnormothermic preservation on extended warm ischemic porcine kidneys assessed by normothermic machine perfusion and renal transplantation.2018
- Author(s)
  Sekijima M, Ariyoshi Y, Sahara H, Kawai A, Iwanaga T, Murokawa T, Ichinari Y, Shimizu A, Kusaka M, Yamada K.
- Organizer
  TTS2018 (27th International Congress of The Transplantation Society).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11201
[Presentation] 独自免疫寛容誘導療法を用いたブタ・ヒヒ間異種腎・異種肺移植－6か月以上の正常ブタ腎機能とブタ特異的免疫無反応ならびに世界最長のブタ肺生着2018
- Author(s)
  山田和彦, 佐原寿史
- Organizer
  第20回日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] Histologically proven survival of porcine lung xenografts in baboons for up to 10 days using double transgenic hCD47/hCD55 GalT-KO donors2017
- Author(s)
  Watanabe H, Sahara H, Nomura S, Tanabe T, Doi R, Ekanayake-Alper D, Boyd L, Danton M, Arn J, Hawley J, Shimizu A, Lorber M, Sykes M, Sachs D, Yamada K
- Organizer
  14th Congress IXA (International Xenotransplantation Association 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] 臓器横断的シンポジウム7「移植後における免疫寛容の誘導」「独自の胸腺移植併用による異種腎移植と遺伝子改変による6か月以上のブタ・ヒヒ間正常異種腎機能と免疫学的抗体ドナー無反応の達成」2017
- Author(s)
  山田和彦, 田邉　起, 佐原寿史, 関島光裕, 田﨑正行
- Organizer
  第53回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] Beneficial effects of hydrogen sulfide (H2S) on renal ischemia-reperfusion Injury (IRI) in CLAWN miniature swine2017
- Author(s)
  Ariyoshi Y, Sekijima M, Sahara H, Murokawa T, Shimizu A, Yamada K
- Organizer
  American Transplant Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10032
[Presentation] 臓器横断的シンポジウム7「移植後における免疫寛容の誘導」「MHC確立クラウン系ミニブタ脳死肺移植モデルを用いた新たな免疫寛容誘導戦略」2017
- Author(s)
  佐原寿史, 岩永健裕, 関島光裕, 有吉勇一, 室川剛廣, 市成ゆりか, 清水　章, 山田和彦
- Organizer
  第53回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] GalT-KOブタ・霊長類間異種肺移植の成績向上2017
- Author(s)
  佐原寿史, 渡邊洋之助, 土肥良一郎, 清水　章, 永安　武, 山田和彦
- Organizer
  第70回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] Successful induction of tolerance of fully allogeneic lung graft with adenosine A2A receptor (A2AR) agonist in MHC-defined CLAWN miniature swine2017
- Author(s)
  Sahara H, Sekijima M, Murokawa T, Ariyoshi Y, Iwanaga T, Ichinari Y, Shimizu A, Yamada K
- Organizer
  American Transplant Congress 2017
- Place of Presentation
  McCormick Place - Lakeside Center (アメリカ合衆国イリノイ州シカゴ)
- Year and Date
  2017-04-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] GalT-KOブタ・ヒヒ間異種肺移植―早期異種移植肺廃絶の回避とその生着2017
- Author(s)
  佐原寿史, 渡邊洋之助, 田邉起, 野村俊一郎, 清水章, 山田和彦
- Organizer
  第19回日本異種移植研究会
- Place of Presentation
  メルパルク京都（京都府京都市）
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] シンポジウム7「異種移植」「世界最長の GalT-KO ブタ・霊長類間異種移植肺生着への道のりと今後の課題」2017
- Author(s)
  佐原寿史, 関島光裕, 山田和彦
- Organizer
  第44回日本臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] MHC確立クラウン系ミニブタを用いた慢性大動物移植実験による常温灌流保存法（NMP法: Normothermic Machine Perfusion）の有効性評価2017
- Author(s)
  関島光裕, 有吉勇一, 佐原寿史, 岩永健裕, 室川剛廣, 市成ゆりか, 清水　章, 山田和彦
- Organizer
  第53回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-17K11201
[Presentation] The beneficial role of adenosine A2A receptor agonist on tolerance induction to fully allogeneic pulmonary allograft in large animal model2017
- Author(s)
  Sahara H, Sekijima M, Iwanaga T, Murokawa T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K
- Organizer
  The 15th Congress of the Asian Society of Transplantation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] MHC確立クラウンミニブタを用いたアデノシンA2A受容体アゴニスト（CGS21680）投与による移植肺免疫寛容誘導2017
- Author(s)
  佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦
- Organizer
  第34回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] Beneficial effects of hydrogen sulfide (H2S) on renal ischemia-reperfusion injury (IRI) in CLAWN miniature swine.2017
- Author(s)
  Ariyoshi Y, Sekijima M, Sahara H, Murokawa T, Shimizu A, Yamada K.
- Organizer
  American Transplant Congress 2017.
- Place of Presentation
  McCormick Place - Lakeside Center（アメリカ合衆国イリノイ州シカゴ）
- Year and Date
  2017-04-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10032
[Presentation] Effect of perioperative treatment with adenosine A2A receptor agonist on pulmonary allograft survival in MHC-inbred CLAWN miniature swine2017
- Author(s)
  Sahara H, Sekijima M, Murokawa T, Ariyoshi Y, Iwanaga T, Ichinari Y, Shimizu A, Yamada K
- Organizer
  International Society for Heart and Lung Transplantation 37th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05432
[Presentation] シンポジウム10. Translational Research. 「硫化水素による新規腎臓保護戦略：臨床応用に向けた大動物実験」2016
- Author(s)
  関島光裕、佐原寿史、山田和彦
- Organizer
  第49回日本臨床腎移植学会
- Place of Presentation
  鳥取県米子市（米子コンベンションセンター）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K10032
[Presentation] Hydrogen sulfide prevents the kidney from ischemia-reperfusion injury in CLAWN miniature swine2016
- Author(s)
  Sekijima M, Sahara H, Morita S, Ogawa Y, Miki K, Murokawa T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K
- Organizer
  26th International Congress of the Transplantation Society
- Place of Presentation
  Hong Kong ( Hong Kong Convention and Exhibition Centre)
- Year and Date
  2016-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10032
[Presentation] 温虚血腎に対する移植前常温持続灌流の有用性－MHC確立クラウン系ミニブタを用いた慢性腎移植2016
- Author(s)
  有吉勇一, 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦
- Organizer
  第4回日本先進医工学ブタ研究会
- Place of Presentation
  静岡県　三島市
- Year and Date
  2016-10-17
- Data Source
  KAKENHI-PROJECT-26293355
[Presentation] 温虚血腎に対する移植前常温持続灌流の有用性－MHC確立クラウン系ミニブタを用いた慢性腎移植.2016
- Author(s)
  有吉勇一, 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦.
- Organizer
  第4回日本先進医工学ブタ研究会．
- Place of Presentation
  東レ総合研修センター（静岡県三島市）
- Year and Date
  2016-10-17
- Data Source
  KAKENHI-PROJECT-15K10032
[Presentation] Hydrogen sulfide prevents the kidney from ischemia-reperfusion injury in CLAWN miniature swine.2016
- Author(s)
  Sekijima M, Sahara H, Morita S, Ogawa Y, Miki K, Murokawa T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K.
- Organizer
  26th International Congress of the Transplantation Society.
- Place of Presentation
  香港会議展覧中心（中国香港）
- Year and Date
  2016-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10032
[Presentation] クラウンミニブタを用いた産学共同前臨床研究の成功例2015
- Author(s)
  小林篤、大原絵里、三浦清豊、徳長靖、山﨑彬、佐原寿史、山田和彦
- Organizer
  第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
- Place of Presentation
  鹿児島大学（鹿児島県鹿児島市）
- Year and Date
  2015-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-26670630
[Presentation] 「医用ミニブタを用いた前臨床研究」．クラウンミニブタを用いた移植モデルとMedical Gas2015
- Author(s)
  佐原寿史、山田和彦
- Organizer
  第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
- Place of Presentation
  鹿児島市
- Year and Date
  2015-03-25
- Data Source
  KAKENHI-PROJECT-26293355
[Presentation] シンポジウム3「畜産研究から実験用ブタへの橋渡しおよび応用研究」高圧下過冷却状態での革新的臓器保存法－前臨床クラウン系ミニブタモデルを用いた産学共同前臨床研究2015
- Author(s)
  小林　篤、大原絵里、三浦清豊、徳長　靖、山崎　彬、佐原寿史、山田和彦
- Organizer
  第3回日本先進医工学ブタ研究会
- Place of Presentation
  東京都千代田区（日本大学会館）
- Year and Date
  2015-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-26670630
[Presentation] シンポジウム5「実験用ブタを用いた各種応用研究」Medical Gasを用いた新たな移植医療：硫化水素の有用性2015
- Author(s)
  佐原寿史、関島光裕、岩永健裕、市成ゆりか、山田和彦
- Organizer
  第3回日本先進医工学ブタ研究会
- Place of Presentation
  東京都
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25461965
[Presentation] Thymic transplantation to determine mechanisms of thymic involution: Insulin-like growth factor 1 receptor and forkhead box protein N1 in the thymus play a role in maintaining the juvenile thymus.2015
- Author(s)
  ekijima M, Tasaki M, Sahara H, Shimizu A, Yamada K
- Organizer
  The 14th Congress of the Asian Society of Transplantation
- Place of Presentation
  Singapore
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293292
[Presentation] 臓器横断的ワークショップ1「臓器移植における新規技術・機器の導入」高圧下過冷却状態での革新的臓器保存法－前臨床クラウン系ミニブタモデルによる開発2015
- Author(s)
  佐原寿史、関島光裕、三浦宏平、河合昭浩、脇　詩織、岩永健裕、市成ゆりか、清水　章、山田和彦
- Organizer
  第51回日本移植学会総会
- Place of Presentation
  熊本県熊本市（ホテル日航熊本）
- Year and Date
  2015-10-01
- Data Source
  KAKENHI-PROJECT-26670630
[Presentation] クラウンミニブタを用いた産学共同前臨床研究の成功例2015
- Author(s)
  小林篤、大原絵里、三浦清豊、徳長靖、山﨑彬、佐原寿史、山田和彦
- Organizer
  第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
- Place of Presentation
  鹿児島大学（鹿児島県鹿児島市）
- Year and Date
  2015-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-25670557
[Presentation] MHC-inbred CLAWN miniature swine as preclinical large animal model for transplantation.2015
- Author(s)
  Sahara H, Iwanaga T, Sekijima M, Waki S, Ichinari Y, Shimizu A, Yamada K
- Organizer
  The 14th Congress of the Asian Society of Transplantation.
- Place of Presentation
  Singapore
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293355
[Presentation] シンポジウム5「実験用ブタを用いた各種応用研究」Medical Gasを用いた新たな移植医療：硫化水素の有用性．2015
- Author(s)
  佐原寿史、関島光裕、岩永健裕、市成ゆりか、山田和彦
- Organizer
  第3回日本先進医工学ブタ研究会
- Place of Presentation
  東京日本大学会館
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26293355
[Presentation] 「臨床医としての医用ミニブタを用いた研究」.腎移植医療の問題点とその対策2015
- Author(s)
  日下　守、佐原寿史、関島光裕、山田和彦
- Organizer
  第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
- Place of Presentation
  鹿児島市
- Year and Date
  2015-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-26293355
[Presentation] シンポジウム「肺移植の現況と将来展」GalT-KO ブタ・カニクイザル間異種肺移植実験の現状 -異種腎臓移植との比較による治療標的の解明と対策2014
- Author(s)
  佐原寿史, 山田和彦
- Organizer
  第31回日本呼吸器外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] シンポジウム「肺移植の現況と将来展」GalT-KOブタ・カニクイザル間異種肺移植実験の現状 - 異種腎臓移植との比較による治療標的の解明と対策．2014
- Author(s)
  佐原寿史、山田和彦
- Organizer
  第31回日本呼吸器外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Establishment of clinically applicable strategy of CO therapy - Beneficial effects of inhaled carbon monoxide to brain-dead donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine.2014
- Author(s)
  Sahara H, Miura K, Waki S, Kawai A, Shimizu A, Yamada K
- Organizer
  World Transplant Congress 2014.
- Place of Presentation
  San Francisco, CA, US
- Data Source
  KAKENHI-PROJECT-25461965
[Presentation] MHC 確立クラウンミニブタ小腸移植手技の工夫2014
- Author(s)
  三浦宏平, 佐原寿史, 河合昭浩, 脇詩織, 清水章, 山田和彦
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390314
[Presentation] Attenuation of hyperacute dysfunction and microangiopathy by the treatment of carbon monoxide in GalT-KO pulmonary xenotransplantation2013
- Author(s)
  Sahara H, Nagashima H, Miura K, Waki S, Kawai A, Nakano K, Matsunari H, Arai Y, Sekijima M, Tasaki M, Setoyama K, Shimizu A, Date H, Yamada K
- Organizer
  12th Congress IXA (International Xenotransplantation Association 2013)
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Beneficial effects of inhaled carbon monoxide (CO) to brain-dead (BD) donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine.2013
- Author(s)
  Miura K, Sahara H, Waki S, Kawai A, Shimizu A, Yamada K
- Organizer
  The 13th Congress of the Asian Society of Transplantation.
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25461965
[Presentation] Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation.2013
- Author(s)
  Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
- Organizer
  The 13th Congress of the Asian Society of Transplantation
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] シンポジウム2「各系統実験用ブタ紹介」MHC確立クラウン系ミニブタを用いた同種移植実験2013
- Author(s)
  佐原寿史
- Organizer
  第1回日本先進医工学ブタ研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24659637
[Presentation] Carbon monoxide (CO) inhalation prolongs survival of the fully MHC-disparate lung graft from brain death donors in miniature swine2013
- Author(s)
  Sahara H, Miura K, Kawai A, Waki S, Sekijima M, Shimizu A, Yamada K
- Organizer
  International Society for Heart and Lung Transplantation 33rd Annual Meeting
- Place of Presentation
  モントリオール
- Data Source
  KAKENHI-PROJECT-24659637
[Presentation] Beneficial effects of inhaled carbon monoxide (CO) to brain-dead (BD) donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine2013
- Author(s)
  Miura K, Sahara H, Waki S, Kawai A, Shimizu A, Yamada K
- Organizer
  The 13th Congress of the Asian Society of Transplantation
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24659637
[Presentation] Carbon monoxide (CO) inhalation prolongs survival of the fully MHC-disparate lung graft from brain death donors in miniature swine2013
- Author(s)
  Sahara H, Miura K, Kawai A, Waki S, Sekijima M, Shimizu A, Yamada K
- Organizer
  International Society for Heart and Lung Transplantation 33rd Annual Meeting
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-24659637
[Presentation] Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation2013
- Author(s)
  Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
- Organizer
  The 13th Congress of the Asian Society of Transplantation
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] シンポジウム2「各系統実験用ブタ紹介」MHC確立クラウン系ミニブタを用いた同種移植実験2013
- Author(s)
  佐原寿史、岩永健裕、山田和彦
- Organizer
  第1回日本先進医工学ブタ研究会
- Place of Presentation
  大阪市
- Year and Date
  2013-11-12
- Data Source
  KAKENHI-PROJECT-24659637
[Presentation] High-Mobility Group Box-1 as a novel therapeutic target for reducing pulmonary ischemia-reperfusion injury in CLAWN miniature swine.2012
- Author(s)
  Sahara H, Shimizu A, Sekijima M, Setoyama K, Oku M, Nishimura H, Yamada K
- Organizer
  24th International Congress of the Transplantation Society
- Place of Presentation
  Berlin
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation.2012
- Author(s)
  Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
- Organizer
  24th International Congress of the Transplantation Society
- Place of Presentation
  Berlin
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] GalT-KO ブタ肺による急性期グラフト機能不全抑制効果の体外循環肺移植モデルによる評価2012
- Author(s)
  佐原寿史, 清水章, 関島光裕, 田崎正行, 瀬戸山健太郎, 長嶋比呂志, 伊達洋至, 山田和彦
- Organizer
  第29回日本呼吸器外科学会総会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Protective effect of anti-high-mobility group box-1 (HMGB1) antibody on pulmonary ischemia-reperfusion injury in miniature swine.2012
- Author(s)
  Sahara H, Shimizu A, Sekijima M, Setoyama K, Oku M, Nishimura H, Yamada K
- Organizer
  International Society for Heart and Lung Transplantation 32nd Annual Meeting
- Place of Presentation
  Prague
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Carbon monoxide　administered only to the donor is sufficient to prolong pulmonary allograft survival across a fully MHC-mismatched barrier in CLAWN miniature swine.2012
- Author(s)
  Sahara H, Sekijima M, Tasaki M, Oku M, Nishimura H, Iwanaga T, Iwanaga T, Sekijima A, Setoyama K, Shimizu A, Yamada K
- Organizer
  24th International Congress of the Transplantation Society
- Place of Presentation
  Berlin
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] High-mobility group box 1（HMGB1）が腎虚血再灌流障害（IRI）進展に及ぼす役割の大動物モデルによる解明2012
- Author(s)
  三浦宏平、佐原寿史、関島光裕、河合昭浩、脇詩織、清水章、山田和彦
- Organizer
  第48回日本移植学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390314
[Presentation] GalT-KOブタ肺による急性期グラフト機能不全抑制効果の体外循環肺移植モデルによる評価2012
- Author(s)
  佐原寿史
- Organizer
  第29回日本呼吸器外科学会総会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Donor preconditioning with carbon monoxide (CO) prolongs lung graft survival in miniature swine.2012
- Author(s)
  Sahara H, Shimizu A, Tasaki M, Sekijima M, Oku M, Nishimura H, Iwamoto E, Setoyama K, Yamada K
- Organizer
  International Society for Heart and Lung Transplantation 32nd Annual Meeting
- Place of Presentation
  Prague
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] ワークショップ【臓器移植に対する先端研究－次世代の実現を目指す戦略－】臓器特異性に基づく新たな異種免疫反応制御戦略－前臨床ブタ・サル移植モデルによる検討2012
- Author(s)
  佐原寿史
- Organizer
  第48回日本移植学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Prevention of hyper-acute pulmonary xenograft dysfunction using GalT-KO swine in an ex-vivo lung perfusion model2011
- Author(s)
  Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
- Organizer
  CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress
- Place of Presentation
  Miami beach, FL, US
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] シンポジウム2.次世代の移植医療に向けて:先端技術を応用した移植医療の開発「臨床応用を目指したブタ・サル間異種移植実験」2011
- Author(s)
  佐原寿史、長嶋比呂志、齋藤敏樹、島津美樹、伊達洋至、清水章、山田和彦
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台市
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] Prevention of hyper-acute pulmonary xenograft dysfunction using GalT-KO swine in an ex-vivo lung perfusion model2011
- Author(s)
  Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
- Organizer
  CTS (Cell Transplant Society)-IXA (International Xenotransplantation Association) 2011 Joint Congress
- Place of Presentation
  マイアミビーチ
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] 体外循環回路を用いたEx-vivo GalT-KOブタ肺移植モデルによる急性期グラフト機能不全抑制効果の評価2011
- Author(s)
  佐原寿史、清水章、関島光裕.田崎正行、瀬戸山健太郎.長嶋比呂志、伊達洋至、山田和彦
- Organizer
  第64回日本胸部外科学会定期学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] シンポジウム2.次世代の移植医療に向けて : 先端技術を応用した移植医療の開発「臨床応用を目指したブタ・サル間異種移植実験」2011
- Author(s)
  佐原寿史, 長嶋比呂志, 齋藤敏樹, 島津美樹, 伊達洋至, 清水章, 山田和彦
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] 肺移植の臨床及び最先端研究の紹介2010
- Author(s)
  佐原寿史
- Organizer
  日本移植者協議会第53回移植セミナー
- Place of Presentation
  鹿児島市
- Year and Date
  2010-07-18
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] MHC確立クラウン系ミニブタ大動物同種移植モデルを用いた移植免疫学的機序に基づく新たな治療戦略の確立2010
- Author(s)
  佐原寿史、屋万栄, 他
- Organizer
  第46回日本移植学会総会
- Place of Presentation
  京都市
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-22591411
[Presentation] Beneficial Effects of Perioperative Low-dose Inhalation of Carbon Monoxide on Pulmonary Allograft Survival in MHC-inbred CLAWN Miniature Swine2010
- Author(s)
  Sahara H, Tasaki M, Setoyama K, Nishimura H, Oku M, Shimizu A, Yamada K
- Organizer
  XXIII International Congress of the Transplantation Society
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-08-18
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Anti-High Mobility Group Box-1 Antibodies Reduce Pulmonary Ischemia Reperfusion Injury in Miniature Swine.2010
- Author(s)
  佐原寿史
- Organizer
  XXIII International Congress of the Transplantation Society
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-08-18
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Symposium 3.Basic, Kidney, liver.Translational Research of Carbon Monoxide (CO) Therapy for Prolonging Pulmonary Allograft Survival using MHC-inbred CLAWN Miniature Swine2010
- Author(s)
  Sahara H, Yamada K
- Organizer
  The 8th Japan-Korea Transplantation Forum
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] 「ワークショップ5.移植免疫における新たな試み」MHC確立クラウン系ミニブタ大動物同種移植モデルを用いた移植免疫学的機序に基づく新たな治療戦略の確立2010
- Author(s)
  佐原寿史、屋万栄、田崎正行、西村博昭、瀬戸山健太郎、Oriyanhan Wunimenghe、奥見雅由、清水章、山田和彦
- Organizer
  第46回日本移植学会総会
- Place of Presentation
  京都
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] ワークショップ:MHC確立クラウン系ミニブタ大動物同種移植モデルを用いた移植免疫学的機序に基づく新たな治療戦略の確立2010
- Author(s)
  佐原寿史
- Organizer
  第46回日本移植学会総会
- Place of Presentation
  京都市
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Anti-High Mobility Group Box-1 Antibodies Reduce Pulmonary Ischemia Reperfusion Injury in Miniature Swine2010
- Author(s)
  Sahara H, Oku M, Setoyama K, Tasaki M, Nishimura H, Oriyanhan W, Okumi M, Shimizu A, Yamada K
- Organizer
  XXIII International Congress of the Transplantation Society
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-08-19
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Carbon Monoxide (CO) Prolongs Survival of Pulmonary Allografts in MHC-inbred CLAWN Miniature Swine2010
- Author(s)
  Sahara H, Setoyama K, Nishimura H, Oriyanhan W, Shimizu A, Yamada K
- Organizer
  International Society for Heart and Lung Transplantation 30th Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Beneficial Effects of Perioperative Low-dose Inhalation of Carbon Monoxide on Pulmonary Allograft Survival in MHC-inbred CLAWN Miniature Swine.2010
- Author(s)
  佐原寿史
- Organizer
  XXIII International Congress of the hansplantation Society
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-08-18
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] 肺移植の臨床及び最先端研究の紹介2010
- Author(s)
  佐原寿史
- Organizer
  日本移植者協議会第53回移植セミナー
- Place of Presentation
  鹿児島招待講演
- Year and Date
  2010-07-18
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] 一酸化炭素(CO)吸入療法によるミニブタ移植肺生着延辰効果:臨床応用を目指した治療戦略2010
- Author(s)
  佐原寿史
- Organizer
  第63回日本胸部外科学会定期学術集会
- Place of Presentation
  大阪市
- Year and Date
  2010-10-25
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] MHC確立クラウン系ミニブタを用いた移植実験-すでにここまで進んでいる2010
- Author(s)
  佐原寿史, シンポジウム
- Organizer
  先進医用ミニブタの開発と前臨床研究拠点プロジェクト第1回シンポジウム
- Place of Presentation
  鹿児島
- Year and Date
  2010-02-23
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] 移植肺生着延長効果を目指した至適一酸化炭素(CO)吸入療法のミニブタ肺移植モデルによる検討2010
- Author(s)
  佐原寿史
- Organizer
  第27回日本呼吸器外科学会総会
- Place of Presentation
  仙台市
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Carbon Monoxide (CO) Prolongs Survival of Pulmonary Allografts in MHC-inbred CLAWN Miniature Swine.2010
- Author(s)
  佐原寿史
- Organizer
  International Society for Heart and Lung Transplantation 30th Annual Meeting
- Place of Presentation
  シカゴ,アメリカ合衆国
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Translational Research of Carbon Monoxide (CO) Therapy for Prolonging Pulmonary Allograft Survival using MHC-inbred CLAWN Miniature Swine.2010
- Author(s)
  佐原寿史
- Organizer
  The 8th Japan-Korea Transplantation Forum
- Place of Presentation
  京都市
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] 「シンポジウム心・肺移植における長期生着阻害因子とその対策」移植肺生着阻害因子としてのMHC 差異・虚血再灌流障害(IRI)及び一酸化炭素(CO)吸入を用いた拒絶抑制効果-MHC確立ミニブタ肺移植モデルによる検討2009
- Author(s)
  佐原寿史、瀬戸山健太郎、西村博昭、W.Oriyanhan、屋万栄、奥見雅由、清水章、山田和彦
- Organizer
  第45回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] クラウン系ミニブタを用いた一酸化炭素吸入による肺虚血再灌流障害抑制効果及びHMGB1の意義2009
- Author(s)
  佐原寿史
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] ミニブタを用いた一酸化炭素(CO)吸入による虚血再灌流障害(IRI)及び移植肺生存延長効果の検討2009
- Author(s)
  佐原寿史
- Organizer
  第26回日本呼吸器外科学会総会
- Place of Presentation
  北九州
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Carbon monoxide inhalation reduces pulmonary ischemia reperfusion injury in miniature swine.2009
- Author(s)
  Sahara H, Oku M, Okumi M, Setoyama K, ShimizuA, YamadaK.
- Organizer
  International Society for Heart and Lung Transpl antation 28th Annual Meeting
- Place of Presentation
  パリ、フランス
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] 移植肺生着阻害因子としてのMHC差異・虚血再灌流障害(IRI)及び一酸化炭素(CO)吸入を用いた拒絶抑制効果2009
- Author(s)
  佐原寿史
- Organizer
  第45回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] Carbon Monoxide Inhalation Reduces Pulmonary Ischemia-Reperfusion Injury in Miniature Swine2009
- Author(s)
  Sahara H, Oku M, Okumi M, Setoyama K, Shimizu A, Yamada K
- Organizer
  International Society for Heart and Lung Transplantation 28th Annual Meeting and Scientific Sessions
- Place of Presentation
  Paris, France
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] 移植肺生着延長効果を目指した至適一酸化炭素(CO)吸入療法のミニブタ肺移植モデルによる検討2009
- Author(s)
  佐原寿史
- Organizer
  第62回日本胸部外科学会定期学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-10-12
- Data Source
  KAKENHI-PROJECT-21791322
[Presentation] BENEFICIAL EFFECTS OF CARBON MONOXIDE ON ISCHEMIA-REPERFUSION INJURY OF LUNG IN MINIATURE SWINE2008
- Author(s)
  Hisashi Sahara
- Organizer
  XXII International Congress of the Transplantation Society
- Place of Presentation
  Sydney
- Year and Date
  2008-08-10
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] 一酸化炭素吸入による肺虚血再灌流障害抑制効果のミニブタモデルを用いた検討2008
- Author(s)
  佐原寿史、屋万栄、奥見雅由、瀬戸山健太郎、清水章、山田和彦
- Organizer
  第44回日本移植学会総会
- Place of Presentation
  大阪
- Year and Date
  2008-09-21
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] ミニブタモデルを用いた一酸化炭素吸入による肺虚血再濯流障害抑制効果及びHMGB1の意義2008
- Author(s)
  佐原寿史
- Organizer
  第61回胸部外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-10-14
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] MHC適合の相違による移植肺拒絶病変進展形式の差異2008
- Author(s)
  佐原寿史、奥見雅由、屋万栄、瀬戸山健太郎、上村亮三、和田洋巳、山田和彦
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] ミニブタモデルを用いた一酸化炭素吸入による肺虚血再灌流障害抑制効果及びHMGB1の意義2008
- Author(s)
  佐原寿史、奥見雅由、屋万栄、瀬戸山健太郎、清水章、山田和彦
- Organizer
  第61回日本胸部外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-10-14
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] クラウン系ミニブタモデルを用いた一酸化炭素吸入の肺虚血再潅流障害抑制効果及びHMGB1に焦点をあてた作用機序の解明一早期臨床応用を目指した大動物モデルによる検討とその発展2008
- Author(s)
  佐原寿史
- Organizer
  第35回日本臓器保存生物医学会定期学術集会
- Place of Presentation
  東京
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] BENEFICIAL EFFECTS OF CARBON MONOXIDE ON ISCHEMIA-REPERFUSION INJURY OF LUNG IN MINIATURE SWINE2008
- Author(s)
  Hisashi Sahara, Manei Oku, Masayoshi Okumi, Kentaro Setoyama, Akira Shimizu, Kazuhiko Yamada
- Organizer
  SWINE. XXII International Congress of the Transplantation Society
- Place of Presentation
  Sydney
- Year and Date
  2008-08-10
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] クラウン系ミニブタモデルを用いた一酸化炭素吸入の肺虚血再灌流障害抑制効果及び HMGB1 に焦点をあてた作用機序の解明一早期臨床応用を目指した大動物モデルによる検討とその発展2008
- Author(s)
  佐原寿史、奥見雅由、屋万栄、瀬戸山健太郎、西村博昭、Wunimenghe Oriyanhan、清水章、山田和彦
- Organizer
  第35回日本臓器保存生物医学会定期学術集会
- Place of Presentation
  東京
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] 一酸化炭素吸入による肺虚血再濯流障害抑制効果のミニブタモデルを用いた検討2008
- Author(s)
  佐原寿史
- Organizer
  第44回日本移植学会総会
- Place of Presentation
  大阪
- Year and Date
  2008-09-21
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] MHC inbredクラウンミニブタにおけるMHC適合の相違による移植肺拒絶病変進展形式の差異2007
- Author(s)
  佐原寿史、奥見雅由、屋万栄、瀬戸山健太郎、上村亮三、清水章、山田和彦
- Organizer
  第43回日本移植学会総会
- Place of Presentation
  仙台
- Year and Date
  2007-11-23
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] Mixed hematopoietic chimerism prevents lung allograft rejection in miniature swine.2007
- Author(s)
  Sahara H, Weiss MJ, Wikiel KJ, Sayre JK, Pujara AC, Ng CY, Cho PL, Horner BM, Houser SL, Wain JC, Sachs DH, Madsen JC, Huang CA, Allan JS.
- Organizer
  International Society for Heart and Lung Transplantation
- Place of Presentation
  San Francisco
- Year and Date
  2007-04-25
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] Thymectomy does not abrogate long-term acceptance of MHC class I-disparate lung allografts.2007
- Author(s)
  Sahara H, Weiss MJ, Ng CY, Houser SL, Pujara AC, Sayre JK, Wain JC, Sachs DH, Madsen JC, Allan JS.
- Organizer
  International Society for Heart and Lung Transplantation
- Place of Presentation
  San Francisco
- Year and Date
  2007-04-27
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] The role of indirect recognition of MHC class I and II allopeptides in lung transplantation in miniature swine.2007
- Author(s)
  Sahara H, Shoji T, Ng CY, Weiss MJ, Muniappan A, Guenther DA, Houser SL, Pujara AC, Sayre JK, Wain JC, Sachs DH, Madsen JC, Allan JS.
- Organizer
  International Society for Heart and Lung Transplantation
- Place of Presentation
  San Francisco
- Year and Date
  2007-04-27
- Data Source
  KAKENHI-PROJECT-19890111
[Presentation] Recent progress in major research laboratories in East Asia - Preclinical study - “Preclinical large animal xenotransplantation projects in Kagoshima”
- Author(s)
  Sahara H, Yamada K
- Organizer
  The 2nd Symposium of the East Asia Xenotransplantation Association
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-23390337
[Presentation] MHC確立クラウンミニブタによる新規治療・医療機器開発を目指す前臨床試験
- Author(s)
  佐原寿史
- Organizer
  BIO tech 2014 アカデミーフォーラム
- Place of Presentation
  東京
- Year and Date
  2014-05-14 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-26293355
[Presentation] 「医用ミニブタを用いた前臨床研究」．クラウンミニブタを用いた移植モデルとMedical Gas
- Author(s)
  佐原寿史、山田和彦
- Organizer
  第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
- Place of Presentation
  鹿児島市
- Year and Date
  2015-03-24 – 2015-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-25461965
[Presentation] MHC確立クラウンミニブタによる新規治療・医療機器開発を目指す前臨床試験
- Author(s)
  佐原寿史
- Organizer
  BIO tech 2014 アカデミーフォーラム
- Place of Presentation
  東京
- Year and Date
  2014-05-14 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-25461965

1. YAMADA Kazuhiko (40241103)

# of Collaborated Projects: 21 results

# of Collaborated Products: 75 results
2. SEKIJIMA Mitsuhiro (20568589)

# of Collaborated Projects: 13 results

# of Collaborated Products: 26 results
3. SHIMIZU Akira (00256942)

# of Collaborated Projects: 12 results

# of Collaborated Products: 38 results
4. 岩永健裕 (40518916)

# of Collaborated Projects: 7 results

# of Collaborated Products: 5 results
5. ARIYOSHI Yuichi (10643520)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
6. NOBORI Shuji (30433288)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. Kusaka Mamoru (40309141)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. 土谷智史 (30437884)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 永安武 (80284686)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. HIRAKATA Atsushi (40468765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. OKU Manei (50550000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. NISHIMURA Masahiro (00294570)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 石井正和 (00456683)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 小戝健一郎 (90258418)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. YOSHIMURA Norio (00191643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAGASHIMA Hiroshi (50318664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
17. DATE Hiroshi (60252962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
18. HOSHINAGA Kiyotaka (30229174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 野崎剛 (00433087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 朝比奈泉 (30221039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山本和子 (10398167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 鳴瀧彩絵 (10508203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 湯川博 (30634646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 諸藤陽一 (40437869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 李桃生 (50379997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 土肥良一郎 (00817786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 加治屋勝子 (00379942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 渡邉洋之助 (30457551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 奥見雅由 (60512978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 河合昭浩 (00617144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 市成ゆりか (50630050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 石井光寿 (60783066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 宮崎拓郎 (00584749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 竹内和博 (50648772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KOBAYASHI Atsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
36. MIURA Kouhei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
37. KAWAI Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. WAKI Shiori

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

SAHARA Hisashi 佐原 寿史

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加齢グラフト内誘導性気管支関連リンパ節の形成過程と大動物移植肺拒絶への関与の解明Principal Investigator

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国際研究ネットワークの構築に基づく異種移植実用化戦略の確立Principal Investigator

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自然・獲得免疫系を繋ぐ肺胞マクロファージの機序解明による同種・異種肺移植成績向上Principal Investigator

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SAHARA Hisashi 佐原寿史