KOSAI Kenichiro 小戝健一郎

… Alternative Names

Researcher Number	90258418 … More / 90301663 Less
Other IDs
Affiliation (Current)	2019: 鹿児島大学, 医歯学域医学系, 教授
Affiliation (based on the past Project Information) *help	2015 – 2019: 鹿児島大学, 医歯学域医学系, 教授 2017: 鹿児島大学, 大学院医歯学総合研究科先進治療科学専攻運動機能修復学講座遺伝子治療・再生医学分野, 教授 2017: 鹿児島大学, 学術研究院医歯学域医学系運動機能修復学講座遺伝子治療・再生医学分野, 教授 2016: 鹿児島大学, 医学部, 教授 2014: 鹿児島大学, 医歯学域医学系運動機能修復学講座遺伝子治療・再生医学分野, 教授 … More
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / General medical chemistry / Orthopaedic surgery / Biological Sciences / Experimental pathology Except Principal Investigator Circulatory organs internal medicine / Ophthalmology / Orthopaedic surgery / Orthodontic/Pediatric dentistry … More
Keywords	Principal Investigator 遺伝子治療 / 再生医学 / アデノウイルスベクター / 遺伝子導入 / 癌 / アデノウイルス / ES細胞 / 遺伝子 / レトロウイルスベクター / Adenovirus … More Except Principal Investigator 遺伝子治療 / アデノウイルスベクター / 脳・神経疾患 / 心筋細胞 / 再生医学 / アポトーシス / 超微形態 / 腫瘍溶解性ウイルス / 超微形態学 / 心不全 / heart failure / 再生医療 / Fas / 骨軟部腫瘍 / apoptosis / 細胞分化 / LPA / 骨増生 / fibrosis / 脳神経疾患 / HTLV-1 bZIP factor / 解剖学 / 骨芽細胞 / 細胞・組織 / sFas gene therapy / Hydrocephalus / アデノウイルス / CD9 / methyl-CpG-binding protein2 / gene therapy / 間葉系幹細胞 / 生理活性 / 脳・神経 / 発生学 / 形態形成 / clearance rate / 骨再生 / サイトカイン / 骨肉腫 / G-CSF / HB-EGF / HGF / degradome / apotosis / TGF-β1 / 生理活性物質 / アポトーシス感受性 / ゲノム創薬 / 細胞周期 / G蛋白共役型リセプター / 癌特異的増殖型アデノウイルス / 分化・増殖 / differentiation and induction / がん遺伝子治療 / オートファジイ / hyaluronan / 顎堤増生 / cardiomyocyte regeneration / TM4SF / Morris water maze / Cell cycle / キメラベクター / ES細胞 / 神経伝達物質 / G-CSF受容体 / 慢性心不全 / metabolic inhibition / 成人T細胞白血病 / histone / デグラドーム / 血管再生 / SDF-1 / 網膜剥離 / ダイレクトリプログラミング / embryonic stem cell / Fasリガンドシステム / ヘミ(X^- / 心筋梗塞 / 顆粒球コロニー刺激因子 / メタロプロテアーゼ / HTLV-1 bZIP factor遺伝子 / Methyl-CpG-binding protein2 / 繊維化 / magnetic resonance imaging / G-protein-coupled receptor / 成人ラット心筋細胞アポトーシスモデル / 代謝抑制 / ウイルス由来遺伝子 / ヒトiPS細胞 / 梗塞後慢性心不全 / 拡張型心筋症 / Fas Ligand system / sensitivity / シャント術 / マウス / autophagy / 糖尿病網膜症 / MAPキナーゼキナーゼ / Rett / 硝子体手術 / 遺伝子・ウイルス治療 / 骨改造 / Mouse / Fas-ligand / 細胞増殖 / 癌特異的増殖型デノウイルス / サバイビン / 分化誘導 / ヒトES細胞 / がん幹細胞 / 心筋再生 / メタロプロデアーゼ / 成人T細胞性白血病 / ヘッジホッグシグナル / Chimera vector / Fas ligand / clearnace rate / caspase / ハムスターUM-X7.1 / 心筋細胞再生 / 交通性水頭症 / プロテインキナーゼC / cell reaction / Cytokine / sFas遺伝子治療 / 破骨細胞 / ヒアルロン酸 / X^-) / TNF-α / caspase3 / 分化・機能活性 / リモデリング / 左室線維化 / Hepatocyte growth factor / Rett Syndrome / methyl-CpG-binding Protein2 / 硝子体免疫 / ES/iPS細胞 / 癌特異的増殖型アデノウイルス / トランスアクチベーション / オートファジー / インターロイキン2 / ビスホスホネート / ヘッジホッグ経路 / 硝子体 / Bc1-2遺伝子治療 / Rett症候群 / 心機能の改善 / ヒトT細胞白血病ウイルスI型 / RPS3 / Y) / regenerative medicine / LV remodeling / ATP感受性Kチャネル / 顆粒球コロニー刺激因子(G-CSF) / 肺転移 / 成人 T 細胞性白血病 / 神経修飾因子 / ネクローシス / 顎骨増生 / neuromodulator / 再生療法 / adenovirus / リゾフォスファチジン酸 / 骨・軟部腫瘍学 / dilated cardiomyopathy / neurotransmitter / myocyte / BRONJ / ultrastructure / 肺癌 / 加齢黄斑変性 / Pulmonary metastasis / retina / 血漿可溶性Fas / miRNA / Mice / Lung cancer / モデル動物 / Hedgehog / 特異的増殖型アデノウイルス / Bcl-2遺伝子治療 / 成人Ｔ細胞白血病 / cerebrospinal fluid / 自殺遺伝子 / 白血病幹細胞 / UM-X 7.1 hamster / Gene therapy / MMP / L型Caチャネル / Ectodomain shedding / 治療薬物 / ATP-sensitive K channel / myocardial infarction / ヒトES/iPS細胞 / 空間認識能 / DAMPs / ヘテロ(X / イオンチャネル / サービビン / DCMハムスターモデル / Transforming growth factor beta1 / osteosarcoma / 左室拡大 / Adenovirus / vitreous body / ヒストン / 炎症 / 細胞破壊物 / ES/iPS / エクトドメインシェディング / 脳室拡大 / remodeling / TGF-beta1 / mouse / MeCP2 / 薬物治療 / GLI2 / 免疫遺伝子ウイルス治療 / 血中sFas / 硝子体細胞 / cytokine / serum sFas / 繊維化抑制 / 心室リモデリング / パッチクランプ法 / ventricular dilatation / 超音波 / TGF-beta / Fasリガンド・システム / 脳・神経学 / model mouse / 成人T細胞白血病幹細胞 / Transactivation / necrosis / hydrocephalus / 癌幹細胞 / 治療法開発 / 特異的増殖型アデノウィルス / 骨・軟部腫瘍 / Interleukin 2 / ヒトT細胞白血病ウィルスI型 / UM-X7.1ハムスター Less

Establishment of efficient myocardial direct reprogramming method using miRNA and elucidation of its molecular basis.Ongoing
- Principal Investigator
  
  三井薫
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kagoshima University
Development of innovative immunovirotherapy facilitating anti-tumor immunity in bone and soft tissue tumorsOngoing
- Principal Investigator
  
  伊地知暢広
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kagoshima University
Rett症候群における新規のエピジェネティックな生理活性物質産生メカニズムの解明Ongoing
- Principal Investigator
  
  入江理恵
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kagoshima University
骨軟部肉腫への腫瘍溶解・免疫誘導・癌幹細胞制圧の革新的な遺伝子ウイルス治療の開発Principal InvestigatorOngoing
- Principal Investigator
  
  小戝健一郎
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Multiple control and visualization of self-somatic- stem cells for atrophic jaw bone augmentationOngoing
- Principal Investigator
  
  西村正宏
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Kagoshima University
ES/iPS細胞由来遺伝子改変破骨細胞によるBRONJ治療法の開発
- Principal Investigator
  
  増原正明
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kagoshima University
骨軟部腫瘍への免疫遺伝子を搭載した増殖型ウイルスの開発Ongoing
- Principal Investigator
  
  伊地知暢広
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Genetically modified virus therapy targeting HTLV-1, a carcinogenic virus
- Principal Investigator
  
  Suzuki Shinsuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical genome science
- Research Institution
  Kagoshima University
Pathogenesis by the analysis of "non" nerve organ of Rett syndrome by the original experimental system with ultrastructure.
- Principal Investigator
  
  Irie Rie
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
Development of a novel orofacial bone regenerative method depending on the angiogenesis and lymphangiogenesis.
- Principal Investigator
  
  Nishimura Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Kagoshima University
Molecular elucidation of normal and cancer stem cells towards development of innovative m-CRA therapy for pediatric cancerPrincipal Investigator
- Principal Investigator
  
  Ken-ichiro Kosai
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
Development of the novel vector system targeting and identifying cancer stem cells for innovative cancer therapy
- Principal Investigator
  
  Ijichi Nobhiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kagoshima University
The development of the novel vector that eliminates ES/iPS cell-derived tumor to realize regenerative medicinePrincipal Investigator
- Principal Investigator
  
  Kosai Ken-ichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Kagoshima University
Study of biology and regulation of vitreous body
- Principal Investigator
  
  SAKAMOTO Taiji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University
GLI2-targeted gene therapy for musculoskeletal tumors
- Principal Investigator
  
  NAGANO Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
The original experiment system elucidates the cause of a patient of RTT syndrome with brain or other organs
- Principal Investigator
  
  IRIE Rie
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
A novel method for identification and isolation of human pluripotent stem cell-derived target cells and elimination of tumorigenic cells.
- Principal Investigator
  
  Mitsui Kaoru
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kagoshima University
Gene therapy of adult T cell leukemia stem cell
- Principal Investigator
  
  SUZUKI Shinsuke
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kagoshima University
Development of conditionally replicating adenovirus that treats human ES/iPS-derived tumorPrincipal Investigator
- Principal Investigator
  
  KOSAI kenichirou
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kagoshima University
A study of osteoblast differentiation and activation in Msx2 gene-transfer ES/iPS cells.
- Principal Investigator
  
  YAMAMOTO Yoshitake
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kagoshima University
The development of conditionally replicating adenovirus targeting cancer stem cell for innovative treatment for pediatric cancerPrincipal Investigator
- Principal Investigator
  
  KOSAI Kenichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
独自開発のm-CRAベクターによる多能性幹細胞由来の腫瘍細胞治療技術の開発Principal Investigator
- Principal Investigator
  
  小戝健一郎
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kagoshima University
Roles of Msx2 in osteoblast proliferation, differentiation and activation for bone remodeling.
- Principal Investigator
  
  YAMAMOTO Yoshitake
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kagoshima University
Study of vitreous body : Analysis of microenvironmental control and development of novel treatment.
- Principal Investigator
  
  SAKAMOTO Taiji
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University
Development of innovative gene therapy of conditionally regulating adenovirus for treating pediatric solid cancerPrincipal Investigator
- Principal Investigator
  
  KOSAI Kenichirou
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
Development of innovative regenerative medicine for pediatric heart diseases using human ES cell and gene therapy technologyPrincipal Investigator
- Principal Investigator
  
  KOSAI Kenichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
  Kurume University
Non-invasive regeneration therapy of dilated cardiomyopathy using G-CSF
- Principal Investigator
  
  FUJIWARA Hisayoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  GIFU UNIVERSITY
Treatment of hydrocephalus using Hepatocyte growth facts (HGF)
- Principal Investigator
  
  TADA Tsuyoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Shinshu University
Molecular Besis of MeCP2 null-mutation Model Mouse and Gene Therapy
- Principal Investigator
  
  MATSUISHI Toyojiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
Ion channel property and ultrastructure in myocyte differentiated and induced from embryonic stem cells.
- Principal Investigator
  
  TSUCHIYA Kunihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  GIFU UNIVERSITY
Development of novel regenerative medicine for congenital diseases using gene therapy biotechnology and embryonic stem cellPrincipal Investigator
- Principal Investigator
  
  KOSAI Ken-ichiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
  Gifu University
New In Vivo Apoptosis Model of Cardiomyocytes and Bcl-2 gene therapy
- Principal Investigator
  
  FUJIWARA Hisayoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University
Soluble Fas, an inhibitor of apoptosis, gene therapy using adenovirus vector for chronic congestive heart failure
- Principal Investigator
  
  NISHIGAKI Kazuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University
Soluble Fas, an inhibitor of apoptosis, gene therapy using adenovirus vector for ischemia-reperfusion injury
- Principal Investigator
  
  MINATOGUCHI Shinya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  GIFU UNIVERSITY
The mechanism of CD9 and development of gene therapy for lung cancer
- Principal Investigator
  
  HAYASHI Akihiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  KURUME UNIVERSITY
新しい増殖制御型アデノウイルスベクター開発による新世代癌遺伝子治療の研究Principal Investigator
- Principal Investigator
  
  小戝健一郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
A development of novel vectors and an establishment of a new generation of hepatic gene therapy for congenital metabolic diseasesPrincipal Investigator
- Principal Investigator
  
  KOSAI Ken-ichiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Gene therapy for skeletal tumors using a newly developed chimera vector
- Principal Investigator
  
  KOMIYA Setsuro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Conversion of membrane-anchored HB-EGF into the soluble form.
- Principal Investigator
  
  MEKADA Eisuke
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
新しいキメラベクターとコンビネーション癌遺伝子治療法の開発Principal Investigator
- Principal Investigator
  
  小戝健一郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kurume University
Development of novel chimeric vector and hepatic gene therapyPrincipal Investigator
- Principal Investigator
  
  KOSAI Ken-ichiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University

[Book] 次世代がん治療第3編ウイルスを用いたがん治療第3章ウイルス治療薬開発『独自開発の多因子増殖制御型アデノウイルス（m-CRA）技術による遺伝子・ウイルス治療薬の臨床開発と実用化の展望』2017
- Author(s)
  伊地知暢広、小戝健一郎
- Total Pages
  347
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860435035
- Data Source
  KAKENHI-PROJECT-16K10869
[Book] iPS細胞作製・培養時における細胞のがん化メカニズムと検出・評価2017
- Author(s)
  三井薫, 小戝健一郎
- Total Pages
  8
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-25293234
[Book] 次世代がん治療研究最前線2017
- Author(s)
  伊地知暢広、小戝健一郎
- Publisher
  株式会社エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-25430153
[Book] iPS細胞培養からがん化の恐れのある細胞を死滅させる方法2016
- Author(s)
  三井薫, 小戝健一郎
- Total Pages
  6
- Publisher
  PHARMSTAGE
- Data Source
  KAKENHI-PROJECT-25293234
[Book] 全日本鍼灸学会雑誌56 (1) : 16-262006
- Author(s)
  小戝健一郎
- Total Pages
  103
- Publisher
  遺伝子治療と再生医学
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591126
[Book] 遺伝子治療と再生医学.全日本鍼灸学会雑誌 56巻1号,16-262006
- Author(s)
  小戝健一郎
- Total Pages
  103
- Publisher
  社団法人全日本鍼灸学会
- Data Source
  KAKENHI-PROJECT-17591126
[Journal Article] A Novel construction of lentiviral vectors for eliminating tumorigenic cells from pluripotent stem cells. Stem Cells2018
- Author(s)
  Ide K, Mitsui K, Irie R, Matsushita Y, Ijichi N, Toyodome S, Kosai KI.
- Journal Title
  
  Stem Cells
  
  Volume: 36 Pages: 230-239
- DOI
  10.1002/stem.2725
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10869, KAKENHI-PROJECT-15K19389, KAKENHI-PROJECT-26860813
[Journal Article] A survivin-responsive, conditionally replicating adenovirus induces potent cytotoxic effects in adult T-cell leukaemia/lymphoma2018
- Author(s)
  Shinsuke Suzuki1,2*+, Hiroki Kofune2+, Kimiharu Uozumi3, Makoto Yoshimitsu2, Naomichi Arima2, Kenji Ishitsuka2, Shin-ichi Ueno1, and Ken-ichiro Kosai4
- Journal Title
  
  Scientific Reports
  
  Volume: ー
- Data Source
  KAKENHI-PROJECT-15K06911
[Journal Article] Viral Vector-based Innovative Approaches to Directly Abolishing Tumorigenic Pluripotent Stem Cells for Safer Regenerative Medicine2017
- Author(s)
  Mitsui K, Ide K, Takahashi T, Kosai K.
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 5 Pages: 51-58
- DOI
  10.1016/j.omtm.2017.03.002
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293234, KAKENHI-PROJECT-16K10002, KAKENHI-PROJECT-15K19389
[Journal Article] Intravenous administration of endothelial colony-forming cells overexpressing integrin b1 augments angiogenesis in ischemic legs.2016
- Author(s)
  Goto K., Takemura G., Takahashi T., Okada H., Kanamori H., Kawamura I., Watanabe T., Morishita K., Tsujimoto A., Miyazaki N., Ushikoshi H., Kawasaki M., Mikami A., Kosai K., Minatoguchi S.
- Journal Title
  
  Stem Cells Transl Med.
  
  Volume: 5 Pages: 218-226
- DOI
  10.5966/sctm.2015-0096
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461568, KAKENHI-PROJECT-25670194, KAKENHI-PROJECT-25293234, KAKENHI-PROJECT-16K10002
[Journal Article] 多能性幹細胞の腫瘍化原因細胞をがん特異的制限増殖型アデノウイルスにより特異的に除去する新技術2016
- Author(s)
  三井薫、小戝健一郎
- Journal Title
  
  BIO INDUSTRY
  
  Volume: 33 (2) Pages: 11-18
- Data Source
  KAKENHI-PROJECT-24591099
[Journal Article] iPS細胞培養からがん化の恐れのある細胞を死滅させる方法2016
- Author(s)
  三井薫、小戝健一郎
- Journal Title
  
  PHARMSTAGE
  
  Volume: 15 (12) Pages: 10-15
- Data Source
  KAKENHI-PROJECT-24591099
[Journal Article] Heparin-Binding Epidermal Growth Factor Like Growth Factor and Hepatocyte Growth Factor Inhibit Cholestatic Liver Injury in Mice via Different Actions.2016
- Author(s)
  Sakamoto K, Khai NC, Wang Y, Irie R, Takamatsu H, Matsufuji H, Kosai K.
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 38 Pages: 1673-1682
- DOI
  10.3892/ijmm.2016.2784
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293234, KAKENHI-PROJECT-26860813
[Journal Article] Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.2016
- Author(s)
  Miyazaki Y, Matsubara S, Qiang Ding, Tsukasa K, Yoshimitsu M, Kosai K, Takao S.
- Journal Title
  
  Mol Cancer
  
  Volume: 10 Pages: 49-49
- DOI
  10.1186/s12943-016-0534-2
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293234, KAKENHI-PROJECT-26462069
[Journal Article] Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias2015
- Author(s)
  Hara M, Takahashi T, Mistumasu C, Igata S, Takano M, Minami T, Yasukawa H, Okayama S, Nakamura K, Okabe Y, Tanaka E, Takemura G, Kosai K, Yamashita Y, Matsuishi T.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Pages: 11204-11204
- DOI
  10.1038/srep11204
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461137, KAKENHI-PROJECT-25461568, KAKENHI-PROJECT-25670194, KAKENHI-PROJECT-26670292, KAKENHI-PROJECT-26860832, KAKENHI-PROJECT-24300145, KAKENHI-PROJECT-25293234
[Journal Article] Conditionally replicating adenovirus prevents pluripotent stem cell-derived teratoma by specifically eliminating undifferentiated cells.2015
- Author(s)
  Kaoru Mitsui, Kanako Ide, Akiko Takayama, Tadahisa Wada, Rie Irie, Ken-ichiro Kosai
- Journal Title
  
  Mol Ther Methods Clin Dev.
  
  Volume: 2 Pages: 15026-15026
- DOI
  10.1038/mtm.2015.26
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591099, KAKENHI-PROJECT-25670194, KAKENHI-PROJECT-25293234
[Journal Article] Pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs in retinochoroidal tissues in rabbits.2014
- Author(s)
  Kida T, Kozai S, Takahashi H, Isaka M, Tokushige H, Sakamoto T.
- Journal Title
  
  Plos One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0096481
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390396
[Journal Article] Intramuscular injection of adenoviral hepatocyte growth factor at a distal site ameliorates dextran sodium sulfate-induced colitis in mice.2014
- Author(s)
  Yuge K, Takahashi T, Khai NC, Goto K, Fujiwara T, Fujiwara H, Kosai K
- Journal Title
  
  Int J Mol Med
  
  Volume: 33(5) Pages: 1064-1074
- DOI
  10.3892/ijmm.2014.1686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159, KAKENHI-PROJECT-25293234, KAKENHI-PROJECT-25461568, KAKENHI-PROJECT-25670194
[Journal Article] Survivin-Responsive Conditionally Replicating Adenovirus Kills Rhabdomyosarcoma Stem Cells More Efficiently Than Their Progeny.2014
- Author(s)
  Tanoue K, Wang Y, Ikeda M , Mitsui K, Irie R , Setoguchi T, Komiya S, Natsugoe S, Kosai K
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 12 Pages: 1-13
- DOI
  10.1186/1479-5876-12-27
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159, KAKENHI-PROJECT-23701062, KAKENHI-PROJECT-24591099, KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-24592238, KAKENHI-PROJECT-24791076, KAKENHI-PROJECT-25293234, KAKENHI-PROJECT-25462342, KAKENHI-PROJECT-25670194
[Journal Article] Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome2012
- Author(s)
  Okabe Y, Takahashi T, Mitsumasu C, Kosai K, MD, Tanaka E, Matsuishi T
- Journal Title
  
  PLOS ONE
  
  Volume: 7(4)
- DOI
  10.1371/journal.pone.0035354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210, KAKENHI-PROJECT-22591144, KAKENHI-PROJECT-23590269, KAKENHI-PROJECT-23659159, KAKENHI-PROJECT-24591531, KAKENHI-PROJECT-24591532
[Journal Article] FAD-dependent lysine demethylase LSD1 regulates cellular energy expenditure2012
- Author(s)
  Hino S, Sakamoto A, Nagaoka K, Anan K, Wang Y, Mimasu S, Umehara T, Yokoyama S, Kosai K, and Nakao M
- Journal Title
  
  Nat. Commun.
  
  Volume: 27;3 Pages: 1-12
- DOI
  10.1038/ncomms1755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210, KAKENHI-PROJECT-22790101, KAKENHI-PROJECT-23659159, KAKENHI-PROJECT-23710226, KAKENHI-PROJECT-24659152, KAKENHI-PLANNED-23116009
[Journal Article] Recombinant soluble form of HB-EGF protein therapy drastically inhibits Fas-mediated fulminant hepatic failure: Implications in clinical application.2011
- Author(s)
  Khai NC, Sakamoto K, Takamatsu H, Matsufuji H, Kosai K.
- Journal Title
  
  Hepatol Res.
  
  Volume: 41 Pages: 594-596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenovlruses (CRA)-Implications for the generation of ideal m-CRAs2011
- Author(s)
  Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S, Kosai K
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 18 Pages: 724-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Neural Development of Methyl-CpG-Binding Protein 2 Null Embryonic Stem Cells: A System for Studying Rett Syndrome.2011
- Author(s)
  Okabe Y, Kusanaga A, Takahashi T, Mitsumasu C, Murai Y, Tanaka E, Higashi H, Matsuishi T, Kosai K
- Journal Title
  
  Brain Res
  
  Volume: 1360(11) Pages: 17-27
- DOI
  10.1016/j.brainres.2010.08.090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis : A novel antiangiogenic therapy2011
- Author(s)
  Kamisasanuki T, Tokushige S, Terasaki H, Khai NC, Wang Y, Sakamoto T, Kosai K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 413(1) Pages: 128-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis: A novel antiangiogenic therapy.2011
- Author(s)
  Kamisasanuki T, Wang Y, Tokushige S, Terasaki H, Khai NC, Wang Y, Sakamoto T, Kosai K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 16 Pages: 128-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Recombinant soluble form of HB-EGF protein therapy drastically inhibits Fas-mediated fulminant hepatic failure : Implications in clinical application.2011
- Author(s)
  Khai NC, Sakamoto K, Takamatsu H, Matsufuji H, Kosai K.
- Journal Title
  
  Hepatology Research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Recombinant soluble form of HB-EGF protein therapy drastically inhibits Fas-mediated fulminant hepatic failure: Implications in clinical application2011
- Author(s)
  Khai NC, Sakamoto K, Takamatsu H, Matsufuji H, Kosai K
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 594-596
- DOI
  10.1111/j.1872-034x.2011.00805.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses (CRA) ⎯Implications for the generation of ideal m-CRAs2011
- Author(s)
  Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S, Kosai K.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: 18 Pages: 724-733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses (CRA)⎯Implications for the generation of ideal m-CRAs2011
- Author(s)
  Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S, Kosai K
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 18(10) Pages: 724-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis.2011
- Author(s)
  Murakami KI, Kaji T, Shimono R, Hyashida Y, Matsufuji H, Tsuyama S, Maezono R, Kosai K, Takamatsu H.
- Journal Title
  
  Pediatr Surg Int.
  
  Volume: 27 Pages: 863-870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Recombinant soluble form of HB-EGF protein therapy drastically inhibits Fas-mediated fulminant hepatic failure : Implications in clinical application2011
- Author(s)
  Khai NC, Sakamoto K, Takamatsu H, Matsufuji H, Kosai K
- Journal Title
  
  Hepatol Res.
  
  Volume: 41 Pages: 594-596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis.2011
- Author(s)
  Murakami KI, Kaji T, Shimono R, Hyashida Y, Matsufuji H, Tsuyama S, Maezono R, Kosai K, Takamatsu H.
- Journal Title
  
  Pediatr Surg Int
  
  Volume: 27(8) Pages: 863-70
- DOI
  10.1007/s00383-011-2853-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis : A novel antiangiogenic therapy2011
- Author(s)
  Kamisasanuki T, Tokushige S, Terasaki H, Khai NC, Wang Y, Sakamoto T, Kosai K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413(1) Pages: 128-135
- URL
  http://dx.doi.org/10.1016/j.bbrc.2011.08.068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390450
[Journal Article] Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis : A novel antiangiogenic therapy2011
- Author(s)
  Kamisasanuki T, Wang Y, Tokushige S, Terasaki H, Khai NC, Wang Y, Sakamoto T, Kosai K
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 16 Pages: 128-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses (CRA) Implications for the generation of ideal m-CRAs.2011
- Author(s)
  Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S, Kosai KI.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 18(10) Pages: 724-33
- DOI
  10.1038/cgt.2011.44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591920, KAKENHI-PROJECT-22390210
[Journal Article] Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis2011
- Author(s)
  Murakami KI, Kaji T, Shimono R, Hyashida Y, Matsufuji H, Tsuyama S, Maezono R, Kosai K, Takamatsu H
- Journal Title
  
  Pediatr Surg Int
  
  Volume: 27(8) Pages: 863-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis: A novel antiangiogenic therapy.2011
- Author(s)
  Kamisasanuki T, Wang Y, Tokushige S, Terasaki H, Khai NC, Wang Y, Sakamoto T, Kosai K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 16;413(1) Pages: 128-35
- DOI
  10.1016/j.bbrc.2011.08.068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis2011
- Author(s)
  Murakami KI, Kaji T, Shimono R, Hyashida Y, Matsufuji H, Tsuyama S, Maezono R, Kosai K, Takamatsu H
- Journal Title
  
  Pediatr Surg Int.
  
  Volume: 27 Pages: 863-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Recombinant soluble form of HB-EGF protein therapy drastically inhibits Fas-mediated fulminant hepatic failure : Implications in clinical application2011
- Author(s)
  Khai NC, Sakamoto K, Takamatsu H, Matsufuji H, Kosai K
- Journal Title
  
  Hepatol Res
  
  Volume: 41(6) Pages: 594-596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659159
[Journal Article] Anti-Fas Gene Therapy Prevents Doxorubicin-induced Acute Cardiotoxicity through Mechanisms Independent of Apoptosis2010
- Author(s)
  Miyata S, Takemura G, Kosai KI, Takahashi T, Esaki M, Li L, Kanamori H, Maruyama R, Goto K, Tsujimoto A, Takeyama T, Kawaguchi T, Ohno T, Nishigaki K, Fujiwara T, Fujiwara H, Minatoguchi S.
- Journal Title
  
  The American Journal of PATHOLOGY 176(2)
  
  Pages: 687-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659072
[Journal Article] Anti-Fas Gene Therapy Prevents Doxorubicin-induced Acute Cardiotoxicity through Mechanisms Independent of Apoptosis2010
- Author(s)
  Miyata S, Takemura G, Kosai KI, Takahashi T, Esaki M, Li L, Kanamori H, Maruyama R, Goto K, Tsujimoto A, Takeyama T, Kawaguchi T, Ohno T, Nishigaki K, Fujiwara T, Fujiwara H, Minatoguchi S.
- Journal Title
  
  The American Journal of PATHOLOGY 176(2)
  
  Pages: 687-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Leptin gene therapy in the fight against diabetes2010
- Author(s)
  Wang Y, Asakawa A, Inui A, Kosai K
- Journal Title
  
  Leptin gene therapy in the fight against diabetes
  
  Volume: 10(10) Pages: 1405-14
- DOI
  10.1517/14712598.2010.512286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Minatoguchi S.Anti-Fas Gene Therapy Prevents Doxorubicin-induced Cardiotoxicity through Mechanisms Independent ofApoptosis.2010
- Author(s)
  Miyata S, Takemura G, Kosai K, Takahashi T, Esaki M, Li L, Kanamori H, Maruyama R, Goto K, Tsujimoto A, Takeyama T, Kawaguchi T, Ohno T, Nishigaki K, Fujiwara T, Fujiwara H, Minatoguchi S
- Journal Title
  
  Am J Pathol
  
  Volume: 176(2) Pages: 687-698
- DOI
  10.2353/ajpath.2010.090222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210, KAKENHI-PROJECT-22591144
[Journal Article] Anti-Fas Gene Therapy Prevents Doxorubicin-induced Acute Cardiotoxicity through Mechanisms Independent of Apoptosis.2010
- Author(s)
  Miyata S, Takemura G, Kosai K, Takahashi T, Esaki M, Li L, Kanamori H, Maruyama R, Goto K, Tsujimoto A, Takeyama T, Kawaguchi T, Ohno T, Nishigaki K, Fujiwara T, Fujiwara H, Minatoguchi S.
- Journal Title
  
  Am J Pathol
  
  Volume: 176(2) Pages: 687-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Leptin gene therapy in the fight against diabetes.2010
- Author(s)
  Wang Y, Asakawa A, Inui A, Kosai K.
- Journal Title
  
  Expert.Opin.Biol.Ther
  
  Volume: 10(10) Pages: 1405-1414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Neural Development of Methyl-CpG-Binding Protein 2 Null Embryonic Stem Cells2010
- Author(s)
  Okabe Y, Kusanaga A, Takahashi T, Mitsumasu C, Murai Y, Tanaka E, Higashi H, Matsuishi T, Kosai K.
- Journal Title
  
  Brain Research
  
  Volume: 1360(11) Pages: 17-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390210
[Journal Article] Postinfarction gene therapy with adenoviral vector expressing decorin mitigates cardiac remodeling and dysfunction2009
- Author(s)
  Li L, Okada H, Takemura G, Kosai KI, Kanamori H, Esaki M, Takahashi T, Goto K, Tsujimoto A, Maruyama R, Kawamura I, Kawaguchi T, Takeyama T, Fujiwara T, Fujiwara H, Minatoguchi S.
- Journal Title
  
  American journal of physiology : Heart and circulatory physiology 294(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659072
[Journal Article] Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure.2009
- Author(s)
  Okada H, Kosai K, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 296(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Efficacy of autologous fat injection laryngoplasty with an adenoviral vector expressing hepatocyte growth factor in a canine model.2009
- Author(s)
  Umeno H, Kosai K, et al.
- Journal Title
  
  J Laryngol Otol 123 Suppl 31
  
  Pages: 24-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Efficacy of autologous fat injection laryngoplasty with an adenoviral vector expressing hepatocyte growth factor in a canine model2009
- Author(s)
  Umeno H, Chitose S, Murofushi Y, Kosai K, Sato K, Kawahara A, Nakashima T.
- Journal Title
  
  The Journal of laryngology and otology 31
  
  Pages: 24-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Efficacy of autologous fat injection laryngoplasty with an adenoviral vector expressing hepatocyte growth factor in a canine model2009
- Author(s)
  Umeno H, Chitose S, Murofushi Y, Kosai K, Sato K, Kawahara A, Nakashima T.
- Journal Title
  
  The Journal of laryngology and otology (31)
  
  Pages: 24-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659072
[Journal Article] Postinfarction gene therapy with adenoviral vector expressing decorin mitigates cardiac remodeling and dysfunction2009
- Author(s)
  Li L, Okada H, Takemura G, Kosai KI, Kanamori H, Esaki M, Takahashi T, Goto K, Tsujimoto A, Maruyama R, Kawamura I, Kawaguchi T, Takeyama T, Fujiwara T, Fujiwara H, Minatoguchi S.
- Journal Title
  
  American journal of physiology : Heart and circulatory physiology 294(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Postinfarction gene therapy with adenoviral vector expressing decorin mitigates cardiac remodeling and dysfunction.2009
- Author(s)
  Li L, Kosai K, et al
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 97(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] 革新的癌治療薬となる遺伝子・ウイルス治療薬と肝疾患への再生医薬.2009
- Author(s)
  室伏善照, 小戝健一郎
- Journal Title
  
  ケミカルエンジニヤリング 54(1)
  
  Pages: 32-38
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Application of an adenoviral vector encoding soluble transforming growth factor-beta type II receptor to the treatment of diabetic nephropathy in mice.2008
- Author(s)
  Kondo T, Kosai K, et al.
- Journal Title
  
  Clin Exp Pharmacol Physiol. 35(11)
  
  Pages: 1288-1293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] 増殖制御型アデノウイルスによる遺伝子治療.2008
- Author(s)
  堀川良治, 小宮節郎, 小戝健一郎
- Journal Title
  
  関節外科基礎と臨床。 27(1)
  
  Pages: 132-133
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Treatment with an adenoviral vector encoding hepatosyte growth factor mitigates established cardiac dysfunction in doxorubicin -induced cardiotnyopathy.2008
- Author(s)
  Esaki M, Takemura G, Kosai KI, Takahashi T, Miyata S, Li L, Goto K, Maruyama R, Okada H, Kanamori, H, Ogino A, Ushikoshi H, Minatoguchi S, Fujiwara T, Fujiwara H.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 294(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Treatment with an adenoviral vector encoding hepatosyte growth factor mitigates established cardiac dysfunction in doxorubicin-induced cardiomyopathy.2008
- Author(s)
  Esaki M, Kosai K, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 294(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Treatment with an adenoviral vector encoding hepatosyte growth factor mitigates established cardiac dysfunction in doxorubicin-induced cardiomyopathy.2008
- Author(s)
  Esaki M, Takemura G, KosaiKI, Takahashi T, Miyata S, Li L, Goto K, Maruyama R, Okada H, Kanamori H, Ogino A, Ushikoshi H, Minatoguchi S, Fujiwara T, Fujiwara H.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 294(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] In vivo hepatocyte growth factor gene transfer reduces myocardial ischemiareperfusion injury through its multiple actions.2007
- Author(s)
  Chen XH, Minatoguchi S, Kosai K, Yuge K, Takahashi T, Arai M, Wang N, Misao Y, Lu C, Onogi H, Kobayashi H, Yasuda S, Ezaki M, Ushikoshi H, Takemura G, Fujiwara T, Fujiwara H.
- Journal Title
  
  J Card Fail. 13(10)
  
  Pages: 874-883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] In vivo hepatocyte growth factor gene transfer reduces myocardial ischemiareperfusion injury through its multiple actions.2007
- Author(s)
  Chen XH, Kosai K, et al.
- Journal Title
  
  J Card Fail. 13(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Postinfarction Gene Therapy Against Transforming Growth Factor-β Signal Modulates Infarct Tissue Dynamics and Attenuates Left Ventricular Remodeling and Heart Failure.2005
- Author(s)
  Okada H, Takemura G, Kosai K, Li Y, Takahashi T, Esaki M, Yuge K, Miyata S, Maruyama R, Mikami A, Minatoguchi S, Fujiwara T, Fujiwara H
- Journal Title
  
  Circulation 111(19)
  
  Pages: 2430-2437
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209027
[Journal Article] 「研究成果報告書概要(欧文)」より2005
- Author(s)
  Tsuyoshi Tada, Jhon Bang Nguyen, Yasuyuki Hitoshi, Nathan P Watson, Jeferry F Dunn, Shinji Ohara, Satoshi Nagano, Ken-ichiro Kosai, Mark A Israel
- Journal Title
  
  Neurological Research 27
  
  Pages: 378-386
- Data Source
  KAKENHI-PROJECT-15390433
[Journal Article] Gene therapy eradicationg, distant disseminated micro metastases by optimal cytokine expression in the primary lesion only : Novel concepts for uccessful cytokine gene therapy.2004
- Author(s)
  Nagano S,... Kosai K
- Journal Title
  
  International Journal of Oncology 24
  
  Pages: 549-558
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] Critical roles for the fas/fas ligand system in postinfarction ventricular remodeling and heart failure.2004
- Author(s)
  Li Y, Takemura G, Kosai K, Takahashi T, Okada H, Miyata S, Yuge K, Nagano S, Esaki M, N.C.Khai, Goto K, Mikami A, Maruyama R, Minatoguchi S, Fujiwara T, Fujiwara H
- Journal Title
  
  Circ Res 95(6)
  
  Pages: 627-636
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209027
[Journal Article] Gene therapy eradicationg, distant disseminated micro metastases by optimal cytokine expression in the primary lesion only ; Novel concepts for uccessful cytokine gene therapy.2004
- Author(s)
  Nagano S, Kosai K, et al.
- Journal Title
  
  International Journal of Oncology 24
  
  Pages: 549-558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] A definitive role of RhoC in metastasis of orthotopic lung cancer in mice2004
- Author(s)
  Ikoma T, Kosai K et al.
- Journal Title
  
  Clinical Cancer Research 10
  
  Pages: 1192-1200
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] A definitive role of RhoC in metastasis of orthotopic lung cancer in mice2004
- Author(s)
  Ikoma T,...Kosai K
- Journal Title
  
  Clinical Cancer Research 10
  
  Pages: 1192-1200
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment.2004
- Author(s)
  Minatoguchi S, Takemura G, Chen X, Wang N, Uno Y, Koda M, Arai M, Misao Y, Lu C, Suzuki K, Goto K, Komada A, Takahashi T, Kosai K, Fujiwara T, Fujiwara H
- Journal Title
  
  Circulation 109(21)
  
  Pages: 2572-2580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209027
[Journal Article] Gene therapy eradicationg, distant disseminated micro metastases by optimal cytokine expression in the primary lesion only : Novel concepts for uccessful cytokine gene therapy.2004
- Author(s)
  Nagano S, Kosai K
- Journal Title
  
  International Journal of Oncology 24
  
  Pages: 549-558
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] A definitive role of RhoC in metastasis of orthotopic lung cancer in mice2004
- Author(s)
  Ikoma T, Kosai K
- Journal Title
  
  Clinical Cancer Research 10
  
  Pages: 1192-1200
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] Postinfarction treatment with an adenovirus vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice2003
- Author(s)
  Li Y,...Kosai K,...Fujiwara H
- Journal Title
  
  Circulation 107
  
  Pages: 2499-2506
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice2003
- Author(s)
  Terazaki Y, Kosai K
- Journal Title
  
  Hepatology 37
  
  Pages: 155-163
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] Postinfarction treatment with an adenovirus vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice2003
- Author(s)
  Li Y, Kosai K, Fujiwara H et al.
- Journal Title
  
  Hepatology 37
  
  Pages: 155-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] C-myc induces autophagy in rat 3Y1 fibroblast cells2003
- Author(s)
  Tsuneoka M..., Kosai K..., Yamamoto A
- Journal Title
  
  Cell Structure and Function 28
  
  Pages: 195-204
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] Postinfarction treatment with an adenoviral vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice.2003
- Author(s)
  Li Y, Takemura G, Kosai K, Yuge K, Nagano S, Esaki M, Goto K, Takahashi T, Hayakawa K, Koda M, Kawase Y, Maruyama R, Okada H, Minatoguchi S, Mizuguchi H, Fujiwara T, Fujiwara H
- Journal Title
  
  Circulation 107(19)
  
  Pages: 2499-2506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209027
[Journal Article] An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice2003
- Author(s)
  Terazaki Y, Kosai K.et al.
- Journal Title
  
  Circulation 107
  
  Pages: 2499-2506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] C-myc induces autophagy in rat 3Y1 fibroblast cells2003
- Author(s)
  Tsuneoka M., Kosai K., Yamamoto A, et al.
- Journal Title
  
  Cell Structure and Function 28
  
  Pages: 195-204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] Postinfarction treatment with an adenovirus vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice2003
- Author(s)
  Li Y, Kosai K, Fujiwara H
- Journal Title
  
  Circulation 107
  
  Pages: 2499-2506
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice2003
- Author(s)
  Terazaki Y,... Kosai K
- Journal Title
  
  Hepatology 37
  
  Pages: 155-163
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370255
[Journal Article] C-myc induces autophagy in rat 3Y1 fibroblast cells2003
- Author(s)
  Tsuneoka M, Kosai K, Yamamoto A
- Journal Title
  
  Cell Structure and Function 28
  
  Pages: 195-204
- Data Source
  KAKENHI-PROJECT-14370255
[Presentation] 増殖制御型アデノウイルスによる癌・再生医学研究へのハムスターモデルの開発2017
- Author(s)
  伊地知暢広、川上広高、小宮節郎、小戝健一郎
- Organizer
  第122回日本解剖学会総会全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-25430153
[Presentation] 遺伝子治療、再生医療の独自開発技術の臨床応用と発生学への展望2017
- Author(s)
  小戝健一郎、三井薫、井手佳菜子、伊地知暢広、入江理恵
- Organizer
  第122回日本解剖学会総会全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K10869
[Presentation] 遺伝子治療、再生医療の独自開発技術の臨床応用と発生学への展望2017
- Author(s)
  小戝　健一郎
- Organizer
  解剖学会
- Place of Presentation
  長崎大学医学部（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 独自開発の多因子制御によるがん特異的増殖型アデノウイルスの肝癌幹細胞への革新的治療作用2017
- Author(s)
  伊地知暢広、田上聖徳、小戝健一郎
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K10869
[Presentation] 増殖制御型アデノウイルスによる癌・再生医学研究へのハムスターモデルの開発2017
- Author(s)
  伊地知暢広、川上広高、小宮節郎、小戝健一郎
- Organizer
  第122回日本解剖学会総会全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K10869
[Presentation] 独自開発の多因子制御によるがん特異的増殖型アデノウイルスの肝癌幹細胞への革新的治療作用2017
- Author(s)
  伊地知暢広、田上聖徳、小戝健一郎
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-25430153
[Presentation] 多因子増殖制御型アデノウイルス（m-CRA）による腫瘍溶解・免疫/遺伝子ウイルス治療への開発2017
- Author(s)
  小戝健一郎
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-25430153
[Presentation] 癌への多因子増殖制御型アデノウイルス(m-CRA)の医師主導治験と免疫遺伝子ウイルス治療への展望2017
- Author(s)
  小戝　健一郎
- Organizer
  日本免疫治療学会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Invited
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 癌への多因子増殖制御型アデノウイルス（m-CRA）の医師主導治験と免疫遺伝子ウイルス治療への展望2017
- Author(s)
  小戝健一郎
- Organizer
  第14回日本免疫治療学研究会学術集会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Data Source
  KAKENHI-PROJECT-16K10869
[Presentation] 多因子増殖制御型アデノウイルス（m-CRA）による腫瘍溶解・免疫／遺伝子ウイルス治療への開発2017
- Author(s)
  小戝健一郎
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K10869
[Presentation] 癌への多因子増殖制御型アデノウイルス（m-CRA）の医師主導治験と免疫遺伝子ウイルス治療への展望2017
- Author(s)
  小戝健一郎
- Organizer
  第14回日本免疫治療学研究会学術集会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Data Source
  KAKENHI-PROJECT-25430153
[Presentation] 遺伝子治療、再生医療の独自開発技術の臨床応用と発生学への展望2017
- Author(s)
  小戝健一郎、三井薫、井手佳菜子、伊地知暢広、入江理恵
- Organizer
  第122回日本解剖学会総会全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-25430153
[Presentation] 多因子増殖制御型アデノウイルス（m-CRA）による腫瘍溶解・免疫／遺伝子ウイルス治療への開発2017
- Author(s)
  小戝　健一郎
- Organizer
  再生医療学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] An efficient construction of lentiviral vectors that identify and eliminate tumorigenic cells in pluripotent stem cells2016
- Author(s)
  井手佳菜子，三井　薫，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 革新的がん治療と幹細胞再生医療の腫瘍化克服を実現する独自開発の遺伝子治療・ウイルスベクター技術と応用2016
- Author(s)
  小戝　健一郎
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] ES/iPS細胞の腫瘍化細胞を可視化・標的殺傷するレンチウイルスベクターの開発と治療効果2016
- Author(s)
  井手佳菜子、三井薫、小戝健一郎
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] ヒトES/iPS細胞における再生医療の課題を克服する独自ウイルスベクターの開発2016
- Author(s)
  三井薫、井手佳菜子、小戝健一郎
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビックパレットふくしま（福島県郡山市）
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] サイトカイン遺伝子搭載腫瘍溶解性アデノウィルス（Surv.m-CRA）開発のための同種移植担癌ハムスターモデルの確立2016
- Author(s)
  川上広高，小濱祐行，伊地知暢弘，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 免疫活性化遺伝子（サイトカイン）を発現する腫瘍溶解性アデノウィルス（Surv.m-CRA）の開発2016
- Author(s)
  小濱祐行，川上広高，伊地知暢弘，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 独自開発の増殖制御型アデノウイルスベクターによるES/iPS細胞の腫瘍化細胞治療技術の発展2016
- Author(s)
  三井　薫、井手　佳菜子、小戝　健一郎
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-24591099
[Presentation] 独自開発の増殖制限型アデノウイルスベクターによるヒトES/iPS細胞の腫瘍化細胞治療技術の発展2016
- Author(s)
  三井薫、井手佳菜子、小戝健一郎
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] ヒトES/iPS細胞における再生医療の課題を克服する独自ウイルスベクターの開発2016
- Author(s)
  三井薫、井手佳菜子、小戝健一郎
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビックパレットふくしま（福島県郡山市）
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] AN EFFICIENT CONSTRUCTION OF LENTIVIRAL VECTORS THAT IDENTIFY AND ELIMINATE TUMORIGENIC CELLS DERIVED FROM PLURIPOTENT STEM CELLS2016
- Author(s)
  Ken-ichiro Kosai, Kanako Ide and Kaoru Mitsui
- Organizer
  ISSCR 2016
- Place of Presentation
  San Francisco, USA
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591099
[Presentation] An efficient construction of lentiviral vectors that identify and eliminate tumorigenic cells in pluripotent stem cells.2016
- Author(s)
  井手佳菜子，三井　薫，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 免疫治療新戦略～ブレイクスルーを超えて～2016
- Author(s)
  小戝　健一郎
- Organizer
  日本遺伝子細胞治療学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] AN EFFICIENT CONSTRUCTION OF LENTIVIRAL VECTORS THAT IDENTIFY AND ELIMINATE TUMORIGENIC CELLS DERIVED FROM PLURIPOTENT STEM CELLS2016
- Author(s)
  Kosai, Ken-ichiro
- Organizer
  International Society for Stem Cell Research（ISSCR）
- Place of Presentation
  San Francisco(USA)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] サイトカイン遺伝子搭載腫瘍溶解性アデノウィルス（Surv.m-CRA）開発のための同種移植担癌ハムスターモデルの確立2016
- Author(s)
  川上広高，小濱祐行，伊地知暢弘，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] がんへの多因子増殖制御型アデノウイルス薬の開発と実用化の展望2016
- Author(s)
  小戝健一郎
- Organizer
  日本臨床腫瘍薬学会学術大会2016
- Place of Presentation
  鹿児島市民文化ホール（鹿児島県鹿児島市）
- Year and Date
  2016-03-12
- Invited
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 独自開発の増殖制御型アデノウィルスベクターm-CRAによるヒト多能性幹細胞の腫瘍化阻止技術2016
- Author(s)
  三井　薫，井手佳菜子，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 独自開発の増殖制限型アデノウイルスベクターによるヒトES/iPS細胞の腫瘍化細胞治療技術の発展2016
- Author(s)
  三井薫、井手佳菜子、小戝健一郎
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 免疫活性化遺伝子（サイトカイン）を発現する腫瘍溶解性アデノウィルス（Surv.m-CRA）の開発2016
- Author(s)
  小濱祐行，川上広高，伊地知暢弘，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] A NOVEL METHOD USING CONDITIONALLY REPLICATING ADENOVIRUS FOR SPECIFICALLY KILLING TUMORIGENIC CELLS DERIVED FROM PLURIPOTENT STEM CELLS2016
- Author(s)
  Kaoru Mitsui, Kanako Ide and Ken-ichiro Kosai
- Organizer
  ISSCR 2016
- Place of Presentation
  San Francisco, USA
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591099
[Presentation] がんへの多因子増殖制御型アデノウイルス薬の開発と実用化の展望2016
- Author(s)
  小戝健一郎
- Organizer
  日本臨床腫瘍薬学会学術大会2016
- Place of Presentation
  鹿児島市民文化ホール（鹿児島県鹿児島市）
- Year and Date
  2016-03-12
- Invited
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] ES/iPS細胞の腫瘍化細胞を可視化・標的殺傷するレンチウイルスベクターの開発と治療効果2016
- Author(s)
  井手佳菜子、三井薫、小戝健一郎
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 胆道閉塞性肝障害マウスモデルにおけるHB-EGFとHGFの異なる再生・治療作用の特性2016
- Author(s)
  入江理恵、坂本浩一、小戝健一郎
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビックパレットふくしま（福島県郡山市）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 胆道閉塞性肝障害マウスモデルにおけるHB-EGFとHGFの異なる再生・治療作用の特性2016
- Author(s)
  入江理恵、坂本浩一、小戝健一郎
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビックパレットふくしま（福島県郡山市）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] ES/iPS細胞の腫瘍化細胞を可視化・標的殺傷するレンチウイルスベクターの開発と治療効果2016
- Author(s)
  井手　佳菜子，三井　薫，小戝　健一郎
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-24591099
[Presentation] 独自開発の増殖制御型アデノウィルスベクターm-CRAによるヒト多能性幹細胞の腫瘍化阻止技術2016
- Author(s)
  三井　薫，井手佳菜子，小戝健一郎
- Organizer
  第９回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] An efficient construction of lentiviral vectors that identify and eliminate tumorigenic cells in pluripotent stem cells.2015
- Author(s)
  Ide K, Mitsui K, Matsushita Y, Kosai K.
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 独自開発の増殖制御型アデノウイルスベクターを用いた新たなES/iPS細胞の腫瘍化細胞除去方法の開発2015
- Author(s)
  三井　薫，井手佳菜子，王　宇清，入江理恵，小戝健一郎
- Organizer
  第８回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2015-01-28
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 本学発のがんへのウィルス医薬～研究と臨床応用の展望2015
- Author(s)
  小戝健一郎
- Organizer
  市民公開講座・鹿児島大学公開講座
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 独自開発の増殖制御型アデノウイルスベクターによる新たなES/iPS細胞の腫瘍化細胞治療技術の開発2015
- Author(s)
  三井薫、井手佳菜子、高山明子、和田忠久、小戝健一郎
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 独自開発の増殖制御型アデノウイルスベクターによる新たなES/iPS細胞の腫瘍化細胞治療技術の開発2015
- Author(s)
  三井薫、井手佳菜子、高山明子、和田忠久、小戝健一郎
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] ES/iPS細胞の腫瘍化細胞を可視化・標的殺傷するレンチウイルスベクターの効率的作製法の開発2015
- Author(s)
  井手佳菜子、三井薫、松下洋平、小戝健一郎
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] Development of the original surviving-responsive conditionally replicating adenovirus toward the investigator-initiated GCP clinical trial.2015
- Author(s)
  Kosai K.
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-07-24
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] Conditionally replicating adenovirus kills tumorigenic pluripotent stem cells.2015
- Author(s)
  Mitsui K, Ide K, Takayama A, Wada T, Irie R, Wang Y, Kosai K.
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] Development of the original surviving-responsive conditionally replicating adenovirus toward the investigator-initiated GCP clinical trial.2015
- Author(s)
  Ken-ichiro Kosai
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-07-24
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 独自開発の増殖制御型アデノウイルスベクターを用いた新たなES/iPS細胞の腫瘍化細胞除去方法の開発2015
- Author(s)
  三井　薫，井手佳菜子，王　宇清，入江理恵，小戝健一郎
- Organizer
  第８回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島鶴陵会館
- Year and Date
  2015-01-28
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 本学発のがんへのウィルス医薬～研究と臨床応用の展望2015
- Author(s)
  小戝健一郎
- Organizer
  市民公開講座・鹿児島大学公開講座
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] ES/iPS細胞の腫瘍化細胞を可視化・標的殺傷するレンチウイルスベクターの効率的作製法の開発2015
- Author(s)
  井手佳菜子、三井薫、松下洋平、小戝健一郎
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] An efficient construction of lentiviral vectors that identify and eliminate tumorigenic cells in pluripotent stem cells.2015
- Author(s)
  Ide K, Mitsui K, Matsushita Y, Kosai K.
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] ES/iPS細胞の腫瘍化細胞を可視化・標的殺傷するレンチウイルスベクターの効率的作製法の開発2015
- Author(s)
  井手佳菜子，三井　薫，松下洋平，小戝健一郎
- Organizer
  第８回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2015-01-28
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] Conditionally replicating adenovirus kills tumorigenic pluripotent stem cells.2015
- Author(s)
  Mitsui K, Ide K, Takayama A, Wada T, Irie R, Wang Y, Kosai K.
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] ES/iPS細胞の腫瘍化細胞を可視化・標的殺傷するレンチウイルスベクターの効率的作製法の開発2015
- Author(s)
  井手佳菜子，三井　薫，松下洋平，小戝健一郎
- Organizer
  第８回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島鶴陵会館
- Year and Date
  2015-01-28
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(1)ヒトES細胞での検証2014
- Author(s)
  井手佳菜子、三井薫、小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 新しい遺伝子治療ウイルスベクターの開発と基礎・臨床への応用2014
- Author(s)
  小戝健一郎
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] アデノウイルスベクターでのヒト多能性幹細胞への効率的遺伝子導入技術の開発2014
- Author(s)
  三井薫、高橋知之、井手佳菜子、小戝健一郎
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] アデノウイルスベクターでのヒト多能性幹細胞への効率的遺伝子導入技術の開発2014
- Author(s)
  三井薫、高橋知之、井手佳菜子、小戝健一郎
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(1)ヒトES細胞での検証2014
- Author(s)
  井手佳菜子、三井薫、小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 癌への遺伝子治療の独自開発と本学での医師主導治験を目指して2014
- Author(s)
  小戝健一郎
- Organizer
  市民公開講座・鹿児島大学公開講座
- Place of Presentation
  鹿児島鶴陵会館
- Year and Date
  2014-07-19
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(1)ヒトES 細胞での検証2014
- Author(s)
  井手佳菜子, 三井薫, 小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島(国内・口頭発表)
- Year and Date
  2014-01-16
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(1)ヒトES細胞での検証2014
- Author(s)
  井手佳菜子、三井薫、小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 新しい遺伝子治療ウイルスベクターの開発と基礎・臨床への応用2014
- Author(s)
  小戝健一郎
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島(国内・ランチョンセミナー)
- Year and Date
  2014-03-16
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(2)マウスES細胞での検証2014
- Author(s)
  松下洋平、井手佳菜子、三井薫、小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(2)マウスES細胞での検証2014
- Author(s)
  松下洋平、井手佳菜子、三井薫、小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(2)マウスES 細胞での検証2014
- Author(s)
  松下洋平, 井手佳菜子, 三井薫, 小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島(国内・口頭発表)
- Year and Date
  2014-01-16
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] アデノウイルスベクターでのヒト多能性幹細胞への効率的遺伝子導入技術の開発2014
- Author(s)
  三井薫、高橋知之、井手佳菜子、小戝健一郎
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] アデノウイルスベクターでのヒト多能性幹細胞への効率的遺伝子導入技術の開発.2014
- Author(s)
  三井薫、高橋知之、井手佳菜子、小戝健一郎
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591099
[Presentation] 多能性幹細胞の再生医療応用における新規腫瘍化阻止技術の開発(2)マウスES細胞での検証2014
- Author(s)
  松下洋平、井手佳菜子、三井薫、小戝健一郎
- Organizer
  第7回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] アデノウイルスベクターでのヒト多能性幹細胞への効率的遺伝子導入技術の開発2014
- Author(s)
  三井薫, 高橋知之, 井手佳菜子, 小戝健一郎
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都(国内・ポスター)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 新しい遺伝子治療ウイルスベクターの開発と基礎・臨床への応用2014
- Author(s)
  小戝健一郎
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 癌への遺伝子治療の独自開発と本学での医師主導治験を目指して2014
- Author(s)
  小戝健一郎
- Organizer
  市民公開講座・鹿児島大学公開講座
- Place of Presentation
  鶴陵会館（鹿児島県鹿児島市）
- Year and Date
  2014-07-19
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] Effects of Msx2 gene on osteogenesis in osteoblasts differentiated from ES/iPS cells2013
- Author(s)
  山本芳丈、三井薫、小戝健一郎、宮脇正一
- Organizer
  日本矯正歯科学会大会
- Place of Presentation
  キッセイ文化ホール、松本市総合体育館
- Data Source
  KAKENHI-PROJECT-23792438
[Presentation] 癌を標的治療する増殖型アデノウイルスの独自技術開発と臨床応用への展望2013
- Author(s)
  小戝健一郎
- Organizer
  鹿児島がんフォーラム
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 増殖型アデノウイルスベクターを用いた安全なヒトES/iPS 細胞治療の開発2013
- Author(s)
  井手佳菜子、三井薫、小戝健一郎
- Organizer
  第6回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] iPS細胞から分化させた骨芽細胞の骨形成に対するMsx２の及ぼす影響2013
- Author(s)
  山本芳丈、三井　薫、小戝健一郎、宮脇正一
- Organizer
  日本矯正歯科学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23792438
[Presentation] 癌を標的治療する増殖型アデノウイルスの独自技術開発と臨床応用への展望2013
- Author(s)
  小戝健一郎
- Organizer
  鹿児島がんフォーラム
- Place of Presentation
  鹿児島
- Year and Date
  2013-11-30
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] Effects of Msx2 gene on osteogenesis in osteoblasts differentiated from ES/iPS cells2013
- Author(s)
  山本芳丈(代表者), 三井薫, 小戝健一郎, 宮脇正一
- Organizer
  日本矯正歯科学会学術大会
- Place of Presentation
  長野
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-23792438
[Presentation] 増殖型アデノウイルスベクターを用いた安全なヒトES/iPS細胞治療の開発2013
- Author(s)
  井手佳菜子, 三井薫, 小戝健一郎
- Organizer
  第6回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島(国内・口頭発表)
- Year and Date
  2013-01-24
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 革新的ながん治療薬(癌だけを殺すウイルス)の開発と臨床応用に向けて2013
- Author(s)
  小戝健一郎
- Organizer
  鹿児島大学公開講座
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 癌を標的治療する増殖型アデノウイルスの独自技術開発と臨床応用への展望2013
- Author(s)
  小戝健一郎
- Organizer
  鹿児島がんフォーラム
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 増殖型アデノウイルスベクターを用いた安全なヒトES/iPS 細胞治療の開発2013
- Author(s)
  井手佳菜子、三井薫、小戝健一郎
- Organizer
  第6回桜ヶ丘地区基礎系研究発表会2013
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 革新的ながん治療薬(癌だけを殺すウイルス)の開発と臨床応用に向けて2013
- Author(s)
  小戝健一郎
- Organizer
  鹿児島大学公開講座
- Place of Presentation
  鹿児島
- Year and Date
  2013-07-27
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 革新的ながん治療薬(癌だけを殺すウイルス)の開発と臨床応用に向けて2013
- Author(s)
  小戝健一郎
- Organizer
  鹿児島大学公開講座
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] Immunohistochemical comparative analysis of the sphere cells of CD133-positive pancreatic cancer cells with iPS cells. CD133+膵がんSphere 形成細胞とiPS 細胞の免疫組織学的比較解析2013
- Author(s)
  宮崎優美, 王宇清, 三井薫, 丁強, 政幸一郎, 松原修一郎, 小戝健一郎, 高尾尊身
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] Development of conditionally replicating adenovirus specifically targeting and/or efficiently treating cancer stem cells.2012
- Author(s)
  Ken-ichiro Kosai
- Organizer
  (国内、口演[English])第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 再生医療と癌の遺伝子治療－技術と臨床応用の現状と展望―2012
- Author(s)
  小戝健一郎
- Organizer
  平成24年度鹿児島大学医学部産科学婦人科学教室碩門会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 独自開発の増殖型アデノウイルスベクターで癌幹細胞は効果的に治療できる2012
- Author(s)
  田上聖徳、王宇清、池田美奈子、三井薫、瀬戸口啓夫、小宮節郎、夏越祥次、小戝健一郎
- Organizer
  (国内・ポスター)第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Efficient treatment of Rhabdomyosarcoma-initiating cells by Survivin-responsive conditionally replicating adenovirus : Promising m-CRA strategy for treating cancer stem cells2012
- Author(s)
  Tanoue K, Wang Y, Ikeda M, Mitsui K, Setoguchi T, Komiya S, Natsugoe S, Kosai K
- Organizer
  The American Society of Gene Therapy’s 15h Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] ヒトES/iPS細胞での再生医療の課題を克服する独自のアデノウイルスベクターと発現技術の開発2012
- Author(s)
  小戝健一郎、三井薫、王宇清、高橋知之
- Organizer
  (国内・パネルディスカッション)第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Survivin-Responsive Conditionally Replicating Adenovirus Efficiently Treats Rhabdomyosarcoma-Initiating Cells2012
- Author(s)
  Kiyonori Tanoue, Yuqing Wang, Takao Setoguchi, Setsuro Komiya, Shoji Natusgoe, Ken-ichiro Kosai
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌(国内, 口演[Japanese])
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 増殖型アデノウイルスベクターを用いた安全なヒトES/iPS細胞治療の開発2012
- Author(s)
  三井薫、井手佳菜子、高山明子、小戝健一郎
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] Efficient treatment of Rhabdomyosarcoma-initiating cells by Survivin-responsive conditionally replicating adenovirus : Promising m-CRA strategy for treating cancer stem cells2012
- Author(s)
  Tanoue K, Wang Y, Ikeda M, Mitsui K, Setoguchi T, Komiya S, Natsugoe S, Kosai K
- Organizer
  The American Society of Gene Therapy’s 15h Annual Meeting
- Place of Presentation
  Philadelphia, USA)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 独自開発の増殖型アデノウイルスベクターで癌幹細胞は効果的に治療できる2012
- Author(s)
  田上聖徳、王宇清、池田美奈子、三井薫、瀬戸口啓夫、小宮節郎、夏越祥次、小戝健一郎
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 癌の遺伝子異常を標的とした診断と治療の可能性2012
- Author(s)
  小戝健一郎
- Organizer
  第175回日本医学放射線学会九州地方会
- Place of Presentation
  鹿児島(国内・特別講演)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 癌の遺伝子異常を標的とした診断と治療の可能性2012
- Author(s)
  小戝　健一郎
- Organizer
  第175回日本医学放射線学会九州地方会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] ヒトES/iPS細胞での再生医療の課題を克服する独自のアデノウイルスベクターと発現技術の開発2012
- Author(s)
  小戝健一郎、三井薫、王宇清、高橋知之
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 再生医療と癌の遺伝子治療-技術と臨床応用の現状と展望-2012
- Author(s)
  小戝健一郎
- Organizer
  平成24年度鹿児島大学医学部産科学婦人科学教室碩門会
- Place of Presentation
  鹿児島(国内・特別講演)
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 癌の遺伝子異常を標的とした診断と治療の可能性2012
- Author(s)
  小戝健一郎
- Organizer
  (国内・特別講演)第175回日本医学放射線学会九州地方会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 再生医療と癌の遺伝子治療－技術と臨床応用の現状と展望2012
- Author(s)
  小戝健一郎
- Organizer
  平成24年度鹿児島大学医学部産科学婦人科学教室碩門会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 独自開発の増殖型アデノウイルスベクターで癌幹細胞は効果的に治療できる2012
- Author(s)
  田上聖徳, 王宇清, 池田美奈子, 三井薫, 瀬戸口啓夫, 小宮節郎, 夏越祥次, 小戝健一郎
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜(国内・ポスター)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] ヒトES/iPS 細胞での再生医療の課題を克服する独自のアデノウイルスベクターと発現技術の開発2012
- Author(s)
  小戝健一郎, 三井薫, 王宇清, 高橋知之
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜(国内・パネルディスカッション)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] Development of conditionally replicating adenovirus specifically targeting and/or efficiently treating cancer stem cells2012
- Author(s)
  Ken-ichiro Kosai
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Survivin-Responsive Conditionally Replicating Adenovirus Efficiently Treats Rhabdomyosarcoma-Initiating Cells2012
- Author(s)
  Kiyonori Tanoue, Yuqing Wang, Takao Setoguchi, Setsuro Komiya, Shoji Natusgoe, Ken-ichiro Kosai.
- Organizer
  国内、口演[Japanese])第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Efficient treatment of Rhabdomyosarcoma-initiating cells by Survivin-responsive conditionally replicating adenovirus : Promising m-CRA strategy for treating cancer stem cells2012
- Author(s)
  Tanoue K, Wang Y, Ikeda M, Mitsui K, Setoguchi T, Komiya S, Natsugoe S, Kosai K
- Organizer
  The American Society of Gene Therapy's 15h Annual Meeting
- Place of Presentation
  Philadelphia, USA(国際・ポスター)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 増殖型アデノウイルスベクターを用いた安全なヒトES/iPS 細胞治療の開発2012
- Author(s)
  三井薫, 井手佳菜子, 高山明子, 小戝健一郎
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜(国内・口演)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] Survivin-Responsive Conditionally Replicating Adenovirus Efficiently Treats Rhabdomyosarcoma-Initiating Cells2012
- Author(s)
  Kiyonori Tanoue, Yuqing Wang, Takao Setoguchi, Setsuro Komiya, Shoji Natusgoe, Ken-ichiro Kosai.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] Development of conditionally replicating adenovirus specifically targeting and/or efficiently treating cancer stem cells2012
- Author(s)
  Ken-ichiro Kosai
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌(国内, 口演[English])
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 増殖型アデノウイルスベクターを用いた安全なヒトES/iPS細胞治療の開発2012
- Author(s)
  三井薫、井手佳菜子、高山明子、小戝健一郎
- Organizer
  (国内・口演)第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Efficient treatment of Rhabdomyosarcoma-initiating cells by Survivin-responsive conditionally replicating adenovirus : Promising m-CRA strategy for treating cancer stem cells2012
- Author(s)
  Tanoue K, Wang Y, Ikeda M, Mitsui K, Setoguchi T, Komiya S, Natsugoe S, Kosai K.
- Organizer
  (国際・ポスター)The American Society of Gene Therapy's 15h Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Cell death in ATL cell lines by survivin-responsive conditionally replicatin g adenoviruses.2011
- Author(s)
  鈴木紳介　魚住公治　小戝健一郎　有馬直道
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23591398
[Presentation] HB-EGF/HGF Hepatic Gene Therapy Effectively Inhibits Bile Duct Ligated Cholestatic Liver Injury In Mice InTheir Different Therapeutic Modes2011
- Author(s)
  Kosai K, Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Hideo T, Matsufuji H
- Organizer
  The American Society of Gene Therapy's 14h Annual Meeting
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 胆道閉塞性肝疾患へのHB-EGF生体内再生医療2011
- Author(s)
  坂本浩一、Ngin Cin Khai、王宇清、前薗理恵、高松英夫、松藤凡、小戝健一郎
- Organizer
  (国内・口演)第10回日本再生医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] HB-EGF/HGF Hepatic Gene Therapy Effectively Inhibits Bile Duct Ligated Cholestatic Liver Injury In Mice In Their Different Therapeutic Modes2011
- Author(s)
  Kosai K, Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Hideo T, Matsufuji H
- Organizer
  The American Society of Gene Therapy's 14h Annual Meeting
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] HB-EGF/HGF HEPATIC GENE THERAPY FOR BILE DUCT LIGATED CHOLESTATIC LIVER INJURY IN MICE: THEIR DIFFERENT AND/OR SYNERGIC THERAPEUTIC EFFECTS2011
- Author(s)
  Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Matsufuji H, Hideo T, Kosai K
- Organizer
  (国内・口演)第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] ASSESSMENT OF AN ALTERED E1B PROMOTER ON THE SPECIFI CITY AND POTENCY OF TRIPLE-REGULATED CONDITIONALLY REPLICATING ADENOVIRUSES (CRA) :A NEW INSIGHT TO GENERATE IDEAL m-CRAs2011
- Author(s)
  Kosai K, Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] MeCP2遺伝子欠損ES細胞のin vitro 文化誘導法によるRett症候群/神経発生の研究システム2011
- Author(s)
  小戝健一郎、岡部共典、久佐賀晃、高橋知之、光益千秋、村井恵良、田中永一郎、松石豊次郎
- Organizer
  (国内・口演)第10回日本再生医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Inhibition Of Choroidal Neovascularization By Targeting To Membrane Protein Cd92011
- Author(s)
  Hiroto Terasaki, Taro Kamisasanuki, Ken-ichiro Kosai, Taiji Sakamoto
- Organizer
  ARVO2011
- Place of Presentation
  Fort Lauderdale・U. S. A
- Year and Date
  2011-05-01
- Data Source
  KAKENHI-PROJECT-20390450
[Presentation] 膜蛋白CD9の標的治療はGeneralに作用する新規血管新生阻害剤となる2011
- Author(s)
  寺崎寛人、上笹貫太郎、徳重沙織、Ngin Cin Khai、Wang Yuqing、坂本泰二、小戝健一郎
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  東京都新宿区
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] HB-EGF/HGF HEPATIC GENE THERAPY FOR BILE DUCT LIGATED CHOLESTATIC LIVER INJURY IN MICE : THEIR DIFFERENT AND/OR SYNERGIC THERAPEUTIC EFFECTS2011
- Author(s)
  Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Matsufuji H, Hideo T, Kosai K
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡(国内・口演)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] MeCP2遺伝子欠損ES細胞のin vitro文化誘導法によるRett症候群/神経発生の研究システム2011
- Author(s)
  小戝健一郎、岡部共典、久佐賀晃、高橋知之、光益千秋、村井恵良、田中永一郎、松石豊次郎
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  東京都新宿区
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] ASSESSMENT OF AN ALTERED E1B PROMOTER ON THE SPECIFICITY AND POTENCY OF TRIPLE-REGULATED CONDITIONALLY REPLICATING ADENOVIRUSES (CRA): A NEW INSIGHT TO GENERATE IDEAL m-CRAS.2011
- Author(s)
  Kosai K, Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S
- Organizer
  (国内・口演)第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] RTTモデルES細胞由来神経細胞の電気生理学的解析2011
- Author(s)
  岡部恭典、久佐賀晃、高橋知之、光益千秋、村井恵良、東英穂、松下豊次郎、小戝健一郎、田中永一郎
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] HB-EGF/HGF HEPATIC GENE THERAPY FOR BILE DUCT LIGATED CHOLESTATIC LIVER INJURY IN MICE : THEIR DIFFERENT AND/OR SYNERGIC THERAPEUTIC EFFECTS2011
- Author(s)
  Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Matsufuji H, Hideo T, Kosai K
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 骨芽細胞分化および骨形成におけるMsx２の関与2011
- Author(s)
  YAMAMOTO　Y., MITSUI K., KOSAI K., MIYAWAKI S.
- Organizer
  日本矯正歯科学会大会＆国際会議
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23792438
[Presentation] HB-EGF/HGF Hepatic Gene Therapy Effectively Inhibits Bile Duct Ligated Cholestatic Liver Injury In Mice In Their Different Therapeutic Modes2011
- Author(s)
  Kosai K, Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Hideo T, Matsufuji H
- Organizer
  第14回米国遺伝子治療学会
- Place of Presentation
  シアトル
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] ASSESSMENT OF AN ALTERED E1B PROMOTER ON THE SPECIFICITY AND POTENCY OF TRIPLE-REGULATED CONDITIONALLY REPLICATING ADENOVIRUSES (CRA) : A NEW INSIGHT TO GENERATE IDEAL m-CRAS2011
- Author(s)
  Kosai K, Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡(国内・口演)
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] 胆道閉塞性肝疾患へのHB-EGF生体内再生医療2011
- Author(s)
  坂本浩一、Ngin Cin Khai、王宇清、前薗理恵、高松英夫、松藤凡、小戝健一郎
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  東京都新宿区
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 膜蛋白CD9の標的治療はGeneralに作用する新規血管新生阻害剤となる2011
- Author(s)
  寺崎寛人、上笹貫太郎、徳重沙織、Ngin Cin Khai、Wang Yuqing、坂本泰二、小戝健一郎
- Organizer
  (国内・口演)第10回日本再生医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] RTT モデルES細胞由来神経細胞の電気生理学的解析2011
- Author(s)
  岡部恭典、久佐賀晃、高橋知之、光益千秋、村井恵良、東英穂、松下豊次郎、小戝健一郎、田中永一郎
- Organizer
  (国内・シンポジウム)第88回日本生理学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Improved survivin-responsive m-CRA for efficient and safer cancer therapy: A new rule of E1B promoter replacement.2010
- Author(s)
  Yoshiharu Horikawa, Ken-ichiro Kosai
- Organizer
  国内・ポスター発表)第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] CD9 siRNA gene therapy inhibits diverse growth factors-induced angiogenesis in vitro and in vivo.2010
- Author(s)
  Taro Kamisasanuki, 小戝健一郎, et al.
- Organizer
  The Association for Research in Vision and Ophthalmology 2010 Annual Meeting
- Place of Presentation
  Florida, USA
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Improved survivin-responsive m-CRA for efficient and safer cancer therapy : A new rule of E1B promoter replacement.2010
- Author(s)
  Yoshiharu Horikawa, Ken-ichiro Kosai
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪県大阪市
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 膜蛋白CD9標的RNAiはGeneralに作用する新たな血管新生阻害剤となる2010
- Author(s)
  上笹貫太郎、徳重沙織、坂本泰二、小戝健一郎
- Organizer
  (国内・ポスター発表)第114回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] Roles of Msx2 gene in osteoblast differentiation and osteogenesis2010
- Author(s)
  山本芳丈(代表)、三井薫、小戝健一郎、宮脇正一
- Organizer
  日本矯正歯科学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-21792090
[Presentation] 先端的治療法の現状と展望遺伝子治療と再生医療を中心に2010
- Author(s)
  小戝健一郎
- Organizer
  鹿児島県医師会学術講演会
- Place of Presentation
  鹿児島
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 膜蛋白CD9標的RNAiはGeneralに作用する新たな血管新生阻害剤となる2010
- Author(s)
  上笹貫太郎、徳重沙織、坂本泰二、小戝健一郎
- Organizer
  第114回日本眼科学会総会
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PROJECT-22390210
[Presentation] 先端的治療法の現状と展望遺伝子治療と再生医療を中心に2010
- Author(s)
  小戝健一郎
- Organizer
  鹿児島県医師会学術講演会
- Place of Presentation
  鹿児島
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-21659072
[Presentation] CD9は血管新生に必須の膜蛋白である;新しい血管新生抑制剤としてのsiRNA CD92009
- Author(s)
  小戝健一郎
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21659072
[Presentation] CD9 siRNA gene therapy can generally inhibit diverse growth factors-induced angiogenesis in vitro and in vivo.2009
- Author(s)
  上笹貫太郎, 坂本泰二, 小戝健一郎
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] CD9発現抑制による新たなRNAi血管新生抑制治療の開発2009
- Author(s)
  上笹貫太郎, 徳重沙織, 坂本泰二, 小戝健一郎
- Organizer
  第3回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] CD9 siRNA gene therapy can generally inhibit diverse growth factors-induced angiogenesis in vitro and in vivo2009
- Author(s)
  上笹貫太郎, 坂本泰二, 小戝健一郎
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21659072
[Presentation] CD9は血管新生に必須の膜蛋白である;新しい血管新生抑制剤としてのsiRNA CD92009
- Author(s)
  小戝健一郎
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 1)癌治療薬とDDSの両事業用のm-CRAベクター、2)肝再生治療薬2009
- Author(s)
  小戝健一郎
- Organizer
  第8回国際バイオEXPO併催国際バイオフォーラム大学・国公立研究所による研究成果発表フォーラム～バイオアカデミックフォーラム～
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] CD9発現抑制による新たなRNAi血管新生抑制治療の開発2009
- Author(s)
  上笹貫太郎, 徳重沙織, 坂本泰二, 小戝健一郎
- Organizer
  第3回桜ヶ丘地区基礎系研究発表会
- Place of Presentation
  鹿児島
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21659072
[Presentation] ヒトES細胞と遺伝子治療2009
- Author(s)
  小戝健一郎
- Organizer
  第49回日本先天異常学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] CD9 as a therapeutic target of ocular diseases(invited speaker symposium)2009
- Author(s)
  Samoto T, Kamisasanuki T, Kosai K.
- Organizer
  8^<th> International symposium of ocular pharmacology and therapeutics
- Place of Presentation
  Rome Cavaliori, Rome, Italy
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20390450
[Presentation] 1)癌治療薬と遺伝子導入試薬の両事業用のm-CRAベクター、2)肝再生治療薬HB-EGF2009
- Author(s)
  小戝健一郎
- Organizer
  バイオジャパン2009 World Business Forum
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659072
[Presentation] 遺伝子治療と再生医学 : 独自のベクター技術を中心に.2009
- Author(s)
  小戝健一郎.
- Organizer
  久留米大学分子生命科学研究所開設20周年記念セミナー(2)
- Place of Presentation
  百年公園久留米リサーチパーク(久留米市)
- Year and Date
  2009-02-13
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 1)癌治療薬とDDSの両事業用のm-CRAベクター、2)肝再生治療薬2009
- Author(s)
  小戝健一郎
- Organizer
  第8回国際バイオEXPO併催国際バイオフォーラム大学・国公立研究所による研究成果発表フォーラム～バイオアカデミックフォーラム～
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659072
[Presentation] ヒトES細胞と遺伝子治療2009
- Author(s)
  小戝健一郎
- Organizer
  第49回日本先天異常学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-21659072
[Presentation] CD9 as a therapeutic target of ocular diseases (invited speaker symposium)2009
- Author(s)
  Sakamoto T, Kamisasanuki T, Kosai S
- Organizer
  8th International symposium of ocular pharmacology and therapeutics.
- Place of Presentation
  Rome Cavaliori, Rome, Italy
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20390450
[Presentation] 1)癌治療薬と遺伝子導入試薬の両事業用のm-CRAベクター、2)肝再生治療薬HB-EGF2009
- Author(s)
  小戝健一郎
- Organizer
  バイオジャパン2009 World Business Forum
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 多因子でウイルス増殖制御/癌特異化するアデノウイルス(m-CRA)の開発と治療応用を目指して2008
- Author(s)
  小戝健一郎
- Organizer
  第12回日本神経ウイルス研究会学術集会
- Place of Presentation
  屋久島(国内・特別講演)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 多因子でウイルス増殖制御/癌特異化するアデノウイルス(m-CRA)の開発と治療応用を目指して.2008
- Author(s)
  小戝健一郎.
- Organizer
  第12回日本神経ウイルス研究会学術集会.
- Place of Presentation
  屋久島環境文化村センター(熊毛郡屋久町)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 遺伝子治療ベクターと再生医学の技術開発と応用2008
- Author(s)
  小戝健一郎
- Organizer
  第113回日本解剖学会総会・全国学術集会
- Place of Presentation
  大分
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Conditionally replicating adenovirus regulated with 4 independent caneer-specific factors enhances cancer-specificity without reducing potentanti-cancer effect ; the importance of EIB promoter.2008
- Author(s)
  Murofushi Y, Nagano S, Komiya S, Kosai K.
- Organizer
  The American Society of Gene Therapy's 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 癌への遺伝子・ウイルス治療薬と肝疾患への再生医薬.2008
- Author(s)
  小戝健一郎
- Organizer
  南九州発新技術説明会
- Place of Presentation
  科学技術振興機構JSTホール(東京都)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Conditionally replicating adenovirus regulated with 4 independent cancer-specific factors enhances cancer-specificity without reducing potent anti-cancer effect ; the importance of E1B promoter.2008
- Author(s)
  室伏善照, 小戝健一郎, et al
- Organizer
  The American Society of Gene Therapy's 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 1. 癌への革新的なウイルス/遺伝子治療薬 2. 肝疾患の再生治療薬.2008
- Author(s)
  小戝健一郎
- Organizer
  イノベーション・ジャパン2008-大学見本市.
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 遺伝子治療と再生医療-高血圧・心疾患の新しい治療戦略-.2008
- Author(s)
  小戝健一郎
- Organizer
  第二十七回二十一人の会
- Place of Presentation
  鹿児島
- Year and Date
  2008-10-07
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 胆道閉鎖動物モデルにおいてビタミンA投与が肝線維化に及ぼす効果(第2報)2007
- Author(s)
  村上研一、高松英夫、田原博幸、下野隆一、林田良啓、小戝健一郎、津山新一郎、前薗理恵
- Organizer
  第107回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Conditionally Replicating Adenovirus Regulated by Survivin and CEA Promoters Exerted More Strict Cancer Specificity and Potent Anti-Cancer Effect.2007
- Author(s)
  Yoshiteru Murofushi, Junichi Kamizono, Ngin Cin Khai, Tomoyuki Takahashi, Setsuro Komiya, Ken-ichiro Kosai.
- Organizer
  第13回日本遺伝子治療学会
- Place of Presentation
  名古屋市(愛知がんセンター)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 多因子増殖制御増殖型アデノウイルスによる新規遺伝子治療法の開発2007
- Author(s)
  神囿純一, 小戝健一郎, 等
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 遺伝子治療と再生医療のシーズの相乗的な事業化2007
- Author(s)
  小戝健一郎
- Organizer
  第6回国際バイオEXPO 併催国際バイオフォーラム大学・国公立研究所による研究成果発表フォーラム〜バイオアカデミックフォーラム〜
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Survivin-Responsive Conditionally Replicating Adenovirus Additionally Regulated with Cancer Specificity without Reducing Anti-Cancer Effect.2007
- Author(s)
  室伏善照, 小戝健一郎, et al.
- Organizer
  The 10th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Seattle, Washington, USA(国際・一般演題)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 胃底腺壁細胞におけるリン酸化エズリン分布の電顕免疫組織化学的検討.2007
- Author(s)
  津山新一郎、前薗理恵、村田長芳、小戝健一郎.
- Organizer
  第48回日本組織細胞化学会総会・学術集会(第8回日中合同組織細胞化学セミナー)
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 壁細胞トランスフォーメーションにおけるリン酸エズリンとCD44の動態解析2007
- Author(s)
  津山新一郎、前薗理恵、小戝健一郎
- Organizer
  第49回日本顕微鏡学会学術講演会
- Place of Presentation
  春日市(九州大学筑紫地区キャンパス)
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Survivin/CEA-responsive conditionally replicating adenovirus enhances cancer specificity with potent anti-cancer effect.2007
- Author(s)
  室伏善照, 神囿純一, 小戝健一郎.
- Organizer
  第66回日本癌学会学術集会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Conditionally Replicating Adenovirus Regulated by Survivin and CEA Promoters Exerted More Strict Cancer Specificity and Potent Anti-Cancer Effect.2007
- Author(s)
  室伏善照, 小戝健一郎, et al.
- Organizer
  第13回日本遺伝子治療学会
- Place of Presentation
  愛知(国内・一般演題)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 独立2～6因子で癌を標的化・治療する癌特異的増殖制御型アデノウイルス2007
- Author(s)
  小戝健一郎, 室伏善照
- Organizer
  第66回日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 遺伝子治療と再生医学の独自技術の開発と応用化.2007
- Author(s)
  小戝健一郎
- Organizer
  イノベーション・ジャパン2007-大学見本市
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 独立2〜6因子で癌を標的化・治療する癌特異的増殖制御型アデノウイルス.2007
- Author(s)
  小戝健一郎, 室伏善照.
- Organizer
  第66回日本癌学会学術集会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Survivin-Responsive Conditionally Replicating Adenovirus Additionally Regulated with Cancer Specificity without Reducing Anti-Cabcer Effect.2007
- Author(s)
  Yoshiteru Murofushi, Junichi Kamizono, Ngin Cin Khai, Tomoyuki Takahashi, Setsuro Komiya, Ken-ichiro Kosai.
- Organizer
  The 10th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Seattle, Washington, USA
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 遺伝子治療と再生医療の独自シーズによる試薬から医薬までの相乗的事業化の提案2007
- Author(s)
  小戝健一郎
- Organizer
  産学協同シーズイノベーション化事業 JST Innovation Bridge 九州・沖縄地区10大学・1高専連携シーズ発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Survivin/CEA-responsive conditionally replicating adenovirus enhances cancer specificity with potent anti-cancer effect.2007
- Author(s)
  室伏善照, 小戝健一郎, 等
- Organizer
  第66回日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 増殖制御型アデノウイルスによる革新的癌治療法の独自開発と臨床応用への展望
- Author(s)
  小戝健一郎
- Organizer
  第29回日本整形外科基礎学術集会
- Place of Presentation
  鹿児島城山観光ホテル
- Year and Date
  2014-10-09 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-25670194
[Presentation] 増殖制御型アデノウイルスによる革新的癌治療法の独自開発と臨床応用への展望
- Author(s)
  小戝健一郎
- Organizer
  第29回日本整形外科基礎学術集会
- Place of Presentation
  城山観光ホテル（鹿児島県鹿児島市）
- Year and Date
  2014-10-09 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-25293234
[Presentation] 革新的癌治療薬を目指した増殖制御型アデノウイルスの独自開発から医師主導治験へ
- Author(s)
  永野　聡，小戝健一郎，小宮節郎
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島市、城山観光ホテル
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] 独自開発の増殖制御型アデノウイルスベクターによる新たなES/iPS細胞の腫瘍化細胞治療技術の開発
- Author(s)
  三井薫、井手佳菜子、高山明子、和田忠久、小戝健一郎
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24591099
[Presentation] HB-EGF/HGF HEPATIC GENE THERAPY FOR BILE DUCT LIGATED CHOLESTATIC LIVER INJURY IN MICE: THEIR DIFFERENT AND/OR SYNERGIC THERAPEUTIC EFFECTS.
- Author(s)
  Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Matsufuji H, Hideo T, Kosai K.
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] HB-EGF/HGF Hepatic Gene Therapy Effectively Inhibits Bile Duct Ligated Cholestatic Liver Injury In Mice In Their Different Therapeutic Modes.
- Author(s)
  Kosai K, Sakamoto K, Khai NC, Wang Y, Maezono R, Tanoue K, Hideo T, Matsufuji H.
- Organizer
  第14回米国遺伝子治療学会
- Place of Presentation
  シアトル
- Data Source
  KAKENHI-PROJECT-23659159
[Presentation] ASSESSMENT OF AN ALTERED E1B PROMOTER ON THE SPECIFICITY AND POTENCY OF TRIPLE-REGULATED CONDITIONALLY REPLICATING ADENOVIRUSES (CRA): A NEW INSIGHT TO GENERATE IDEAL m-CRAS.
- Author(s)
  Kosai K, Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S.
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23659159

1. IRIE Rie (90381178)

# of Collaborated Projects: 10 results

# of Collaborated Products: 27 results
2. MITSUI Kaoru (40324975)

# of Collaborated Projects: 9 results

# of Collaborated Products: 52 results
3. IJICHI Nobuhiro (80380624)

# of Collaborated Projects: 7 results

# of Collaborated Products: 13 results
4. KOSAI Kenichirou (90301663)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. FUJIWARA Hisayoshi (80115930)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
6. TAKAHASHI Tomoyuki (20332687)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. AKEMURA Genzo (40283311)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
8. KOMIYA Setsuro (30178371)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
9. MEKADA Eisuke (20135742)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. SUZUKI Shinsuke (20437974)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. SAKAMOTO Taiji (10235179)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
12. MARUYAMA Ikuro (20082282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TAKAO Sonshin (80171411)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
14. NAGANO Satoshi (50373139)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
15. YAMAMOTO Yoshitake (50380465)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
16. KONDO Toru (30270573)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. WAN Yu-chin (20505143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
18. Nishimura Masahiro (00294570)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. KUNISADA Takahiro (30205108)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 朝比奈泉 (30221039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. HASHIGUCHI Teruto (70250917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SETOGUCHI Takao (40423727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. UENO Shinichi (40322317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. SONODA Koh-hei (10294943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SUDA Yasuo (70179282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ITO Hiroshi (40223177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. UMADA Toshiyuki (30213482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MIYADO Kenji (60324844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. IWAMOTO Ryo (10213323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. TSUNEOKA Makoto (50197745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. YOSHINO Makoto (40080569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. NISHIGAKI Kazuhiko (60198447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. MINATOGUCHI Shinya (20190697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. HAYASHI Akihiro (70180958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. TERAZAKI Yasuhiro (30279187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. MATSUISHI Toyojiro (60157237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
37. YAMASHITA Yushiro (90211630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. KOGA Yasutoshi (00225400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. KONDO Ikuko (20110489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. TAKASHIMA Sachio (70038743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. TSUCHIYA Kunihiko (30313878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. ARAI Masazumi (00202721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
43. TADA Tsuyoshi (00236530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
44. TANAKA Yuichiro (70192177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. NAKAMURA Toshikazu (00049397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. MAENO Yasuki (90248401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 魚住公治 (90253864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
48. 白水和雄 (20216203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 河野嘉文 (20260680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 室伏善照 (50448578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
51. 山田源 (80174712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 永光信一郎 (30258454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 増原正明 (70372901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 佐藤友昭 (10284887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. 上川善昭 (30332901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. 石井正和 (00456683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. 山田和彦 (40241103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. TANIGUCHI Noboru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. ISHIDOU Yasuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. OKABE Yasunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
61. UMEHARA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. HINO Shinjiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. KAMIZONO Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
64. 高橋和之

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results
65. 安川秀雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
66. 田中永一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
67. 鷹野誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
68. 原宗嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 山下潤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
70. 西芳寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
71. 井手佳菜子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
72. 松原修一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOSAI Kenichiro 小戝 健一郎

KOSAI Kenichirou 小財 健一郎

Research Projects

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Establishment of efficient myocardial direct reprogramming method using miRNA and elucidation of its molecular basis.Ongoing

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Development of innovative immunovirotherapy facilitating anti-tumor immunity in bone and soft tissue tumorsOngoing

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Rett症候群における新規のエピジェネティックな生理活性物質産生メカニズムの解明Ongoing

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骨軟部肉腫への腫瘍溶解・免疫誘導・癌幹細胞制圧の革新的な遺伝子ウイルス治療の開発Principal InvestigatorOngoing

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Multiple control and visualization of self-somatic- stem cells for atrophic jaw bone augmentationOngoing

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骨軟部腫瘍への免疫遺伝子を搭載した増殖型ウイルスの開発Ongoing

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Molecular elucidation of normal and cancer stem cells towards development of innovative m-CRA therapy for pediatric cancerPrincipal Investigator

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The development of the novel vector that eliminates ES/iPS cell-derived tumor to realize regenerative medicinePrincipal Investigator

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KOSAI Kenichiro 小戝健一郎

KOSAI Kenichirou 小財健一郎