• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

YAMADA Kazuhiko  山田 和彦

ORCIDConnect your ORCID iD *help
Researcher Number 40241103
External Links
Affiliation (based on the past Project Information) *help 2018 – 2021: 鹿児島大学, 総合科学域総合研究学系, 教授
2014 – 2017: 鹿児島大学, 学内共同利用施設等, 教授
2012 – 2017: 鹿児島大学, 医用ミニブタ・先端医療開発研究センター, 教授
2015 – 2016: 鹿児島大学, 医用ミニブタ・先端医療開発研究センター 臓器置換・異種移植外科分野, 教授
2013: 鹿児島大学, 医用ミニブタ・先端医療開発 研究センター, 教授 … More
2012: 鹿児島大学, 医用ミニブタ先端医療開発研究センター, 教授
2007 – 2011: Kagoshima University, フロンティアサイエンス研究推進センター, 教授
2007 – 2008: 鹿児島大学, 学内共同利用施設等, 教授
2005: Harvard University School of Medicine, Surgery, Associated Professor Less
Review Section/Research Field
Principal Investigator
General surgery / Basic Section 55010:General surgery and pediatric surgery-related
Except Principal Investigator
General surgery / Urology / Thoracic surgery / Respiratory surgery / Clinical veterinary science / Prosthodontics/ Dental materials science and / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 56030:Urology-related / Basic Section 55040:Respiratory surgery-related
Keywords
Principal Investigator
免疫寛容 / キメラ / トランスレーショナルリサーチ / 移植・再生医療 / 腎移植 / 膵島移植 / 小腸移植 / ミニブタ / トランスレーショナル研究 / 異種移植 … More / ブタ・サル間移植 / GalKOブタ / 遺伝子導入 / hCD47 / 組織適合性抗原 / GvH / GvHR / キメリズム / 主要組織適合性抗原 / サイトカイン / 腸間膜リンパ節 / 抗HMGB1抗体 / 前臨床実験 / 高圧 / 臓器保存 / 心移植 / 大動物 / 腎臓移植 / 骨髄移植 / サル / 外科 / カニクイザル / 膵島・腎移植 / クラウン系ミニブタ / 体外循環 / 前臨床研究 / MHC / 移植片対宿主反応 … More
Except Principal Investigator
ミニブタ / 移植・再生医療 / 腎移植 / 虚血再灌流障害 / トランスレーショナルリサーチ / 前臨床研究 / 免疫寛容 / 前臨床実験 / 肺移植 / 臓器保護 / 一酸化炭素 / マージナルドナー / 異種移植 / 自然免疫 / HGF / 膵島移植 / 胸腺 / マクロファージ / 移植外科学 / 異種肺移植 / 間葉系幹細胞 / 常温腎臓持続体外灌流保存 / miniature swine / CAV / 心移植 / MHC / 臓器灌流保存 / タクロリムス / 犬 / MRI / 異種抗原 / イヌ / ブタ / 若年化再生 / テストステロン / 制御性 T 細胞 / 制御性T細胞 / 移植免疫寛容 / 末梢性免疫寛容 / CFSE-MLR / 移植後免疫寛容 / 膵島・腎移植 / 血管再構築 / GalT-KOブタ / カニクイザル / 急性期肺機能不全 / Ex-vivo灌流 / CalT-KOブタ / 血小板 / 肺血管抵抗 / 脳死 / 脳死ドナー / 移植・再生 / 虚血再潅流障害 / 移植 再生医療 / HMGB1 / 臓器保存 / 高圧 / 非凍結 / クラウン系ミニブタ / SLA遺伝子 / 胸腺移植 / SLA class I, II遺伝子 / PCR-SSP / PCR-RFL / miniature pig / SLA class I, II / PCR-RFLP / genotyping / RT-PCR / SBT / SLA / tolerance / vascularized thymic lobe / 硫化水素 / 腎臓体外灌流保存 / 霊長類 / CD47 / アデノシンA2A受容体 / 外科 / 移植免疫 / 虚血再還流障害 / i移植免疫 / 常温灌流保存 / 虚血再灌流傷害 / 温虚血 / 浸漬冷却保存 / 再生医療 / 骨再生 / 再生医学 / 骨増生 / 移植心冠動脈病変 / 加齢 / 動脈硬化 / ヒトアポリポ蛋白(a) / 動脈硬化モデルミニブタ / 動脈硬化促進遺伝子導入MHC確立ミニブタ / 灌流保存 / 肺胞マクロファージ / トランスレーショナル研究 Less
  • Research Projects

    (25 results)
  • Research Products

    (223 results)
  • Co-Researchers

    (35 People)
  •  Preclinical study on organ preconditioning before transplantation for marginal grafts

    • Principal Investigator
      Kusaka Mamoru
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Fujita Health University
  •  前臨床モデルでの移植片対宿主反応(LGVHR)に基づく革新的小腸移植免疫寛容誘導Principal Investigator

    • Principal Investigator
      山田 和彦
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kagoshima University
  •  自然・獲得免疫系を繋ぐ肺胞マクロファージの機序解明による同種・異種肺移植成績向上

    • Principal Investigator
      佐原 寿史
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Kagoshima University
  •  Mechanism of development of cardiac allograft vasculopathy following heart transplantation using genetically engineered MHC-defined miniature swine.

    • Principal Investigator
      SEKIJIMA Mitsuhiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kagoshima University
  •  Development of protection and repair of preserved organs using small interfering RNA (siRNA) in large animal model .

    • Principal Investigator
      Nobori Shuji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Normothermic machine perfusion of the kidney to evaluate the donor organ before transplantation: Preclinical large animal study using MHC-defined CLAWN miniature swine

    • Principal Investigator
      ARIYOSHI Yuichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Multiple control and visualization of self-somatic- stem cells for atrophic jaw bone augmentation

    • Principal Investigator
      NISHIMURA Masahiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      Kagoshima University
  •  Establish a treatment strategy to diabetic nephropathy using combined kidney and islets transplantationPrincipal Investigator

    • Principal Investigator
      YAMADA Kazuhiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kagoshima University
  •  Modulation of inflammation and innate immune responses subsequent to endothelial cell damage in lung allo and xenotransplantation

    • Principal Investigator
      SAHARA Hisashi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory surgery
    • Research Institution
      Kagoshima University
  •  Establishment of hydrogen sulfide therapy against renal ischemia-reperfusion injury using large animal to attempt to increase the donor organ pool

    • Principal Investigator
      SEKIJIMA Mitsuhiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kagoshima University
  •  Induction of tolerance by rejuvenation of thymus in preclinical large animal model.

    • Principal Investigator
      Nobori Shuji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Preclinical study on protection strategy and function recovery strategy of preimplantation for marginal graft

    • Principal Investigator
      Kusaka Mamoru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Fujita Health University
  •  Establishment of novel lung preservation method in a stable unfrozen state under high pressurized condition

    • Principal Investigator
      SAHARA HISASHI
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory surgery
    • Research Institution
      Kagoshima University
  •  Effects of carbon monoxide inhalation on allograft survival of the lung or kidney from brain death donors in miniature swine.

    • Principal Investigator
      HIRAKARA Atsushi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nippon Medical School
  •  New organ preservation method under pressurized, non-frozen condition: Preclinical study using CLAWN miniature swinePrincipal Investigator

    • Principal Investigator
      YAMADA Kazuhiko
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Kagoshima University
  •  Establishment of a new strategy to improve graft function after lung transplantation from brain-dead donors using mesenchymal stem cells - preclinical study using MHC-inbred CLAWN miniature swine

    • Principal Investigator
      SAHARA Hisashi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Thoracic surgery
    • Research Institution
      Kagoshima University
  •  Intestinal Transplantation in CLAWN Miniature Swine: Establishment of Orthotopic Model and Roles of Chimerisms, HVG and GVH ResponsesPrincipal Investigator

    • Principal Investigator
      YAMADA Kazuhiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kagoshima University
  •  Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation

    • Principal Investigator
      SAHARA Hisashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kagoshima University
  •  Attempt to induce tolerance of kidneys by pharmacologic rejuvenation of thymus in miniature swine

    • Principal Investigator
      NOBORI Shuji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  前臨床ミニブタ同種腎移植モデルを用いたHGFによる免疫寛容誘導および機序の解明

    • Principal Investigator
      OKU Manei
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kagoshima University
  •  Role of prevascularization of islets in the induction of tolerance of allogeneic islets in miniature swine

    • Principal Investigator
      HIRAKATA Atsushi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nippon Medical School
  •  イヌ糖尿病根治治療を目指したブタ膵島移植-免疫寛容誘導に向けた基礎的研究-

    • Principal Investigator
      瀬戸山 健太郎
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Kagoshima University
  •  GalT-knockout pig to monkey xenogeneic kidney and islet transplantationPrincipal Investigator

    • Principal Investigator
      YAMADA Kazuhiko
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Kagoshima University
  •  Effect of HGF on chronic changes in renal allografts in partial ly inbred miniature swine

    • Principal Investigator
      SADA Masaharu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Induction of transplantation tolerance by co-transplantation of vascularized thymic lobe in miniature swine

    • Principal Investigator
      SADA Masaharu
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      National Cardiovascular Center, Research Institute

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] Kidney Transplantation - New Perspectives: Chapter 9: Mechanisms of Tolerance: Role of the Thymus and Persistence of Antigen in Calcineurin-Induced Tolerance of Renal Allografts in MGH Miniature Swine2011

    • Author(s)
      Joseph R. Scalea, Isabel Hanekamp and Kazuhiko Yamada* (* 責任著者) InTech
    • Data Source
      KAKENHI-PROJECT-22390249
  • [Book] Kidney Transplantation-New Perspectives : Chapter 9 : Mechanisms of Tolerance : Role of the Thymus and Persistence of Antigen in Calcineurin-Induced Tolerance of Renal Allografts in MGH Miniature Swine2011

    • Author(s)
      Joseph R.Scalea, Isabel Hanekamp, Kazuhiko Yamada*(*責任著者)
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-22390249
  • [Book] Living Donor Organ Transplantation(Editors : Rainer Gruessner,, Enrico Benedetti)(McGraw Hill, Medical 全791頁分担 Chapter : Xenotransplantation分担)2007

    • Author(s)
      Yamada K.
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Book] Living Donor Organ Transplantation (Editors: Rainer Gruessner,, Enrico Benedetti) 分担 Chapter: Xenotransplantation2007

    • Author(s)
      Yamada K, Vallabhajosyula P, Sachs DH
    • Total Pages
      791
    • Publisher
      McGraw Hill, Medical
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival.2020

    • Author(s)
      Watanabe H, Ariyoshi Y, Pomposelli T, Takeuchi K, Ekanayake-Alper DK, Boyd LK, Arn SJ, Sahara H, Shimizu A, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K.
    • Journal Title

      Xenotransplantation

      Volume: 27

    • DOI

      10.1111/xen.12552

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09722, KAKENHI-PROJECT-19H03748
  • [Journal Article] Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine.2019

    • Author(s)
      Sekijima M, Sahara H, Shimizu A, Iwanaga T, Murokawa T, Ariyoshi Y, Pomposelli T, Khosravi Maharlooei M, Sykes M, Yamada K.
    • Journal Title

      Xenotransplantation.

      Volume: 26

    • DOI

      10.1111/xen.12543

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09722
  • [Journal Article] GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels2018

    • Author(s)
      Watanabe H、Sahara H、Nomura S、Tanabe T、Yamada Kazuhiko et al.
    • Journal Title

      Xenotransplantation

      Volume: 印刷中

    • DOI

      10.1111/xen.12391

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Journal Article] Lung xenotransplantation2017

    • Author(s)
      Sahara Hisashi、Watanabe Hironosuke、Pomposelli Thomas、Yamada Kazuhiko
    • Journal Title

      Current Opinion in Organ Transplantation

      Volume: 22 Pages: 541-548

    • DOI

      10.1097/mot.0000000000000465

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Journal Article] Hydrogen sulfide prevents renal ischemia-reperfusion injury in CLAWN miniature swine2017

    • Author(s)
      Sekijima Mitsuhiro、Sahara Hisashi、Miki Katsuyuki、Villani Vincenzo、Ariyoshi Yuichi、Iwanaga Takehiro、Tomita Yusuke、Yamada Kazuhiko
    • Journal Title

      Journal of Surgical Research

      Volume: 219 Pages: 165-172

    • DOI

      10.1016/j.jss.2017.05.123

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10032
  • [Journal Article] Effects of carbon monoxide on early dysfunction and microangiopathy following GalT-KO porcine pulmonary xenotransplantation in cynomolgus monkeys2017

    • Author(s)
      Sahara Hisashi、Sekijima Mitsuhiro、Ariyoshi Yuichi、Kawai Akihiro、Miura Kohei、Waki Shiori、Nathan Louras、Tomita Yusuke、Iwanaga Takehiro、Nakano Kazuaki、Matsunari Hitomi、Date Hiroshi、Nagashima Hiroshi、Shimizu Akira、Yamada Kazuhiko
    • Journal Title

      Xenotransplantation

      Volume: 25

    • DOI

      10.1111/xen.12359

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Journal Article] 特集「毒ガス?いいえ治療薬です」.【新たな治療薬としての一酸化炭素への期待】2016

    • Author(s)
      佐原寿史, 関島光裕, 山田和彦
    • Journal Title

      臨床麻酔

      Volume: 39(6) Pages: 855-864

    • Data Source
      KAKENHI-PROJECT-26293355
  • [Journal Article] 特集「毒ガス?いいえ治療薬です」.【新たな治療薬としての一酸化炭素への期待】.2015

    • Author(s)
      佐原寿史, 関島光裕, 山田和彦
    • Journal Title

      臨床麻酔

      Volume: 39(6) Pages: 855-864

    • Data Source
      KAKENHI-PROJECT-26293355
  • [Journal Article] 特集「毒ガス?いいえ治療薬です」.【新たな治療薬としての一酸化炭素への期待】2015

    • Author(s)
      佐原寿史, 関島光裕, 山田和彦
    • Journal Title

      臨床麻酔

      Volume: 6 Pages: 855-864

    • Data Source
      KAKENHI-PROJECT-25461965
  • [Journal Article] Protective effect of neutralization of the extracellular high-mobility group box-1 on renal ischemia-reperfusion injury in miniature swine.2014

    • Author(s)
      Miura K, Sahara H, Sekijima M, Kawai A, Waki S, Nishimura H, Setoyama K, Clayman ES, Shimizu A, Yamada K.
    • Journal Title

      Transplantation

      Volume: Nov 15;98(9) Pages: 937-943

    • DOI

      10.1097/tp.0000000000000358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461965, KAKENHI-PROJECT-26293355
  • [Journal Article] Abrogation of renal allograft tolerance in MGH miniature swine: The role of intra-graft and peripheral factors in long-term tolerance.2014

    • Author(s)
      Scalea JR, Okumi M, Villani V, Shimizu A, Nishimura H, Gillon BC, Torabi R, Cormack T, Moran S, LeGuern C, Sachs DH, Yamada K.
    • Journal Title

      Am J Transplant

      Volume: 14 (9) Pages: 2001-2010

    • DOI

      10.1111/ajt.12816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293292
  • [Journal Article] Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates.2013

    • Author(s)
      Okumi M, Scalea JR, Gillon BC, Tasaki M, Villani V, Cormack T, Hirakata A, Shimizu A, Sachs DH, Yamada K.
    • Journal Title

      Xenotransplantation

      Volume: 13 Pages: 1193-1202

    • DOI

      10.1111/ajt.12194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591417, KAKENHI-PROJECT-23390337
  • [Journal Article] The induction of tolerance of renal allografts by adoptive transfer in miniature Swine.2013

    • Author(s)
      Okumi M, Hirakata A, Yamada K
    • Journal Title

      Am J Transplant.

      Volume: 13(5) Pages: 1193-202

    • Data Source
      KAKENHI-PROJECT-22591417
  • [Journal Article] 大動物を用いた前臨床虚血再灌流障害モデルの作製とマージナルドナー活用戦略2013

    • Author(s)
      山田和彦, 佐原寿史
    • Journal Title

      Organ Biology

      Volume: 20 Pages: 42-50

    • Data Source
      KAKENHI-PROJECT-25461965
  • [Journal Article] Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates2013

    • Author(s)
      Shimatsu Y, Yamada K, Horii W, Hirakata A, Sakamoto Y, Waki S, Sano J, Saitoh T, Sahara H, Shimizu A, Yazawa H, Sachs DH, Nunoya T
    • Journal Title

      Xenotransplantation

      Volume: 20(3) Pages: 157-64

    • DOI

      10.1111/xen.12031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] Hepatocyte growth factor sustains tregs and prolongs the survival of kidney allografts in MHC-inbred CLAWN-miniature swine. Transplantation. 2012 Jan 27 ; 93(2) : 148-552012

    • Author(s)
      Oku M, et al.
    • Journal Title

      Transplantation

      Volume: 93 Pages: 148-155

    • DOI

      10.1097/tp.0b013e31823be83f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590742, KAKENHI-PROJECT-22591411
  • [Journal Article] Thymic transplantation in pig-to-nonhuman primates for the induction of tolerance across xenogeneic barriers2012

    • Author(s)
      Yamada K
    • Journal Title

      Methods Mol Biol

      Volume: 885 Pages: 191-212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390249
  • [Journal Article] Current progress in xenogeneic tolerance2012

    • Author(s)
      Yamada K, Scalea J
    • Journal Title

      Curr Opin Organ Transplant

      Volume: 17(2) Pages: 168-73

    • DOI

      10.1097/mot.0b013e32835090f6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] ドナーに対する一酸化炭素吸入療法による移植肺生着延長効果:前臨床ミニブタモデルを用いた新たな臓器保存方法への発展2012

    • Author(s)
      佐原寿史、山田和彦
    • Journal Title

      Organ Biology

      Volume: 19 Pages: 11-14

    • NAID

      130004710024

    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] Current progress in xenogeneic tolerance.2012

    • Author(s)
      Yamada K, Scalea J.
    • Journal Title

      Current Opinion in Organ Transplantation

      Volume: 17 Pages: 168-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] T-cell-mediated immunological barriers to xenotransplantation2012

    • Author(s)
      Scalea J, Hanecamp I, Robson SC, Yamada K
    • Journal Title

      Xenotransplantation

      Volume: 19 Pages: 23-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] ドナー臓器の機能評価および修復を可能とする常温体外肺循環回路(EVLP)下での一酸化炭素吸入療法によるミニブタ移植肺生着延長効果の検討2012

    • Author(s)
      佐原寿史、脇 詩織、関島光裕、三浦宏平、河合昭浩、清水 章、山田和彦
    • Journal Title

      今日の移植

      Volume: 25 Pages: 495-499

    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] Composite islet-kidneys from single baboon donors cure diabetes acrossfully allogenic barriers2011

    • Author(s)
      Yamada K, Hirakata A, Tchipashvili V, Shimizu A, Iwaki H, et al
    • Journal Title

      American Journal of Transplantation

      Volume: 11 Pages: 2603-2612

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591417
  • [Journal Article] 異種移植2011

    • Author(s)
      山田和彦、佐原寿史
    • Journal Title

      医学のあゆみ 237

      Pages: 559-566

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] 異種臓器移植の臨床応用をめざして-前臨床異種移植はここまで進んでいる2011

    • Author(s)
      山田和彦、佐原寿史
    • Journal Title

      医学のあゆみ

      Volume: 237(5) Pages: 559-566

    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] Quantification of baboon thymopoiesis in porcine thymokidney xenografts by the signal-joining T-cell receptor excision circle assay.2011

    • Author(s)
      Tena A, Vallabhajosyula P, Hawley RJ, Griesemer A, Yamada K, Sachs DH.
    • Journal Title

      Transplantation

      Volume: 91 Pages: 639-644

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] 異種臓器移植の臨床応用をめざして-前臨床異種移植はここまで進んでいる2011

    • Author(s)
      山田和彦, 佐原寿史
    • Journal Title

      医学のあゆみ

      Volume: 237(5) Pages: 559-66

    • URL

      http://www.ishiyaku.co.jp/magazines/ayumi/AyumiArticleDetail.aspx?BC=286290&AC=10269

    • Data Source
      KAKENHI-PROJECT-23390337
  • [Journal Article] Composite islet-kidneys from single baboon donors cure diabetes across fully allogenic barriers.2011

    • Author(s)
      Yamada K and Hirakata A
    • Journal Title

      Am J Transplant.

      Volume: 11(12) Pages: 2603-12

    • Data Source
      KAKENHI-PROJECT-22591417
  • [Journal Article] Signal joint T-cell receptor excision circle assay in miniature Swine2011

    • Author(s)
      Yamada K
    • Journal Title

      Transplantation

      Volume: 92(6) Pages: 634-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390249
  • [Journal Article] 異種移植2011

    • Author(s)
      山田和彦、佐原寿史
    • Journal Title

      医学のあゆみ

      Volume: 91(掲載予定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Reversal of age-related thymic involution by an LHRH agonist in miniature swine.2010

    • Author(s)
      Hirakata A, Nobori S, YamadaK, et al.
    • Journal Title

      Transpl Immunol

      Volume: 24 Pages: 76-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591417
  • [Journal Article] Survey of glycoantigens in cells from alphal-3galactosyltransferase knockout pig using a lectinmicroarray2010

    • Author(s)
      Miyagawa S, Takeishi S, Yamamoto A, Ikeda K, Matsunari H, Yamada M, Okabe M, Miyoshi E, Fukuzawa M, Nagashima H
    • Journal Title

      Xenotransplantation 17

      Pages: 61-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Reversal of age-related thymic involution by an LHRH agonist in miniature swine.2010

    • Author(s)
      Hirakata A and Yamada K
    • Journal Title

      Transpl Immunol.

      Volume: 24(1) Pages: 76-81

    • Data Source
      KAKENHI-PROJECT-22591417
  • [Journal Article] Histopathology of xenografts in pig to non-human primate discordant xenotransplantation.2010

    • Author(s)
      Shimizu A, Yamada K.
    • Journal Title

      Clin Transplant. 24

      Pages: 11-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Reversal of age-related thymic involution by an LHRH agonist in miniature swine.2010

    • Author(s)
      Hirakata A, Nobori S, Yamada K, et al.
    • Journal Title

      Transpl Immunol

      Volume: 24 Pages: 76-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390249
  • [Journal Article] Histopathology of xenografts in pig to non-human primate discordant xenotransplantation.2010

    • Author(s)
      Shimizu A, Yamada K
    • Journal Title

      Clin Transplant

      Volume: 24 Pages: 11-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Reversal of age-related thymic involution by an LHRH agonist in miniature swine.2010

    • Author(s)
      Hirakata A, Okumi M, Griesemer AD, Shimizu A, Nobori S, Tena A, Moran S, Arn S, Boyd RL, Sachs DH, Yamada K.
    • Journal Title

      Transpl Immunol

      Volume: 24 Pages: 76-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Reversal of age-related thymic involution by an LHRH agonist in miniature swine2010

    • Author(s)
      Hirakata A, Nobori S, Yamada K
    • Journal Title

      Transpl Immunol

      Volume: 24 Pages: 76-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390249
  • [Journal Article] Reversal of age-related thymic involution by an LHRH agonist in miniature swine.2010

    • Author(s)
      Hirakata A, Okumi M, Shimizu A, Yamada K, et al.
    • Journal Title

      Transpl Immunol 24

      Pages: 76-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Upregulation of CD59 : potential mechanism of accommodation in a large animal model2009

    • Author(s)
      Griesemer AD, Okumi M, Shimizu A, Moran S, Ishikawa Y, Iorio J, Arn JS, Yamada K
    • Journal Title

      Transplantation 87(9)

      Pages: 1308-17

    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Upregulation of CD59 : Potential mechanism of accommodation in alarge animal model2009

    • Author(s)
      Griesemer AD, Okumi M, Shimizu A, Moran S, Ishikawa Y, Iorio J, Arn S, Yamada K.
    • Journal Title

      Transplantation 87(9)

      Pages: 1308-1317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Results of gal-knockout porcine thymokidney xenografts2009

    • Author(s)
      Griesemer AD, Hirakata A, Shimizu A, Moran S, Tena A, Iwaki H, Ishikawa Y, Schule P, Arn JS, Robson SC, Fishman JA, Sykes M, Sachs DH, Yamada K.
    • Journal Title

      American Journal of Transplantation 9(12)

      Pages: 2669-2678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Upregulation of CD59 : Potential mechanism of accommodation in a large animal model.2009

    • Author(s)
      Griesemer AD, Okumi M, Shimizu A, Yamada K.
    • Journal Title

      Transplantation 87

      Pages: 1308-1317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Upregulation of CD59 : Potential mechanism of accommodation in alarge animal model2009

    • Author(s)
      Griesemer AD, Okumi M, Shimizu A, Moran S, Ishikawa Y, Iorio J, Arn S, Yamada K.
    • Journal Title

      Transplantation 87(印刷中In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Results of gal-knockout porcine thymokidney xenografts2009

    • Author(s)
      Griesemer AD, Hirakata A, Shimizu A, Moran S, Tena A, Iwaki H, Ishikawa Y, Schule P, Arn JS, Robson SC, Fishman JA, Sykes M, Sachs DH, Yamada K
    • Journal Title

      Am J Transplant. 9(12)

      Pages: 2669-78

    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays2008

    • Author(s)
      Oku M, Okumi M, Sahara H, Hirakata A, Onoe T, Griesemer AD, Yamada K
    • Journal Title

      Transplant Immunology 20

      Pages: 78-82

    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Linked suppression across an MHC-mismatched barrier in a miniature swine kidney transplantation model2008

    • Author(s)
      Griesemer AD, LaMattina JC, Okumi M, Shimizu A, Sachs DH, Yamada K
    • Journal Title

      Journal of Immunology 181 (6)

      Pages: 4027-4036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Journal Article] Linked suppression across an MHC-mismatched barrier in a miniature swine kidney transplantation model2008

    • Author(s)
      Griesemer AD, LaMattina JC, Okumi M, Shimizu A, Sachs DH, Yamada K. (Yamada K : 責任著者)
    • Journal Title

      Journal of Immunology 181(6)

      Pages: 4027-4036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Journal Article] Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays2008

    • Author(s)
      Oku M, Okumi M, Sahara H, Hirakata A, Onoe T, Griesemer AD, Yamada K. (Yamada K : 責任著者)
    • Journal Title

      Transplant Immunology 20

      Pages: 78-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Journal Article] Role of persistence of antigen and indirect recognition in the maintenance of tolerance to renal allografts2008

    • Author(s)
      Okumi M, Fishbein JM, Griesemer AD, Gianello PR, Hirakata A, Nobori S, Moran S, Samelson-Jones E, Shimizu A, Sachs DH, Yamada K
    • Journal Title

      Transplantation 85(2)

      Pages: 270-280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Journal Article] Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays2008

    • Author(s)
      Oku M, Okumi M, Sahara H, Hirakata A, Onoe T, Griesemer AD, Yamada K
    • Journal Title

      Transplant Immunology 20 (1-2)

      Pages: 78-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Journal Article] Secretory unit of islet in transplantation (SUIT) and engraftedislet rate (EIR) indexes are useful for evaluating single islettransplantation2008

    • Author(s)
      Noguchi H, Yamada Y, Okitsu T, Iwanaga Y, Nagata H, Kobayashi N, Hayashi S, Matsumoto S.
    • Journal Title

      Cell Transplant 17(1-2)

      Pages: 121-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays.2008

    • Author(s)
      Oku M, Okumi M, Sahara H, Yamada K, et al.
    • Journal Title

      Transplant Immunology 20

      Pages: 78-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays2008

    • Author(s)
      Oku M, Okumi M, Sahara H, Hirakata A, Onoe T, Griesemer AD, Yamada K.
    • Journal Title

      Transplant Immunology 20(1-2)

      Pages: 78-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Role of persistence of antigen and indirect recognition in the maintenance of tolerance to renal allografts.2007

    • Author(s)
      Okumi M, Fishbein JM, Griesemer AD, Gianello PR, Hirakata A, Nobori S, Moran S, Samelson-Jones E, Shimizu A, Sachs DH, Yamada K^* (^*Corresponding author).
    • Journal Title

      Transplantation 85(2)

      Pages: 270-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] GalT-KO pigs: is the cup half empty or half full?2007

    • Author(s)
      Sachs DH, Yamada K, Robson SC, Fishman JA, Shimizu A, Colvin RB, Sykes M
    • Journal Title

      Transplantation 84(1)

      Pages: 12-4

    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Vascularized composite islet-kidney transplantation in a miniature swine model2007

    • Author(s)
      Vallabhajosyula P, Griesemer A, Yamada K, Sachs DH.
    • Journal Title

      Cell Biochem Biophys 48

      Pages: 201-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Journal Article] Role of the thymus in transplantation tolerance in miniature swine : V.Deficiency of the graft-to-thymus pathway of tolerance induction in recipients of cardiac transplants.2006

    • Author(s)
      Yamamoto S, Teranishi K, Kamano C, Samelson-Jones E, Arakawa H, Nobori S, Okumi M, Houser S, Shimizu A, Sachs DH, Yamada K
    • Journal Title

      Transplantation 81(4)

      Pages: 607-613

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Long-term accetance of fully allogeneic cardiac graftas by cotransplantation of vascularized thymus in miniature swine2006

    • Author(s)
      S.Nobori, E Samelson-Jones, A.Shimizu, Y.Hisashi, C.Kamano, K.Yamada et al.
    • Journal Title

      Transplantation 15

      Pages: 26-35

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Long-term acceptance of fully allogeneic cardiac grafts by cotransplantation of vascularized thymus in miniature swine.2006

    • Author(s)
      Nobori S, Samelson-Jones E, Shimizu A, Hisashi Y, Yamamoto S, Kamano C, Teranishi K, Vagefi PA, Nuhn M, Okumi M, Wong B, Houser S, Sachs DH, Yamada K
    • Journal Title

      Transplantation 81(1)

      Pages: 26-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Role of the thymus in transplantation tolerance in miniature swine : V.Deficiency of the graft-to-thymus pathway of tolerance induction in recipients of cardiac transplants2006

    • Author(s)
      S.Yamamoto, K.Teranishi, C.Kamano, E.Samelson-Jones, K.Yamada et al.
    • Journal Title

      Transplantation 27

      Pages: 607-613

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Thrombotic Microangiopathic Glomerulopathy in Human Decay Accelerating Factor-Transgenic Swine-to-Baboon Kidney Xenografts.2005

    • Author(s)
      Shimizu A, Yamada K, Yamamoto S, Lavelle JM, Barth RN, Robson SC, Sachs DH, Colvin RB
    • Journal Title

      J Am Soc Nephrol 16(9)

      Pages: 2732-2745

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors : initial experience.2005

    • Author(s)
      Kuwaki K, Tseng YL, Dor FJ, Shimizu A, Houser SL, Sanderson TM, Lancos CJ, Prabharasuth DD, Cheng J, Moran K, Hisashi Y, Mueller N, Yamada K, Greenstein JL, Hawley RJ, Patience C, Awwad M, Fishman JA, Robson SC, Schuurman HJ, Sachs DH, Cooper DK
    • Journal Title

      Nature Medicine 11(1)

      Pages: 29-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months.2005

    • Author(s)
      Tseng YL, Kuwaki K, Dor FJ, Shimizu A, Houser S, Hisashi Y, Yamada K, Robson SC, Awwad M, Schuurman HJ, Sachs DH, Cooper DK
    • Journal Title

      Transplantation 80(10)

      Pages: 1493-1500

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Potential of aspirin to inhibit thrombotic microangiopathy in alpha1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboons.2005

    • Author(s)
      Dor FJ, Kuwaki K, Tseng YL, Shimizu A, Houser SL, Yamada K, Hawley RJ, Patience C, Awwad M, Fishman JA, Robson SC, Sachs DH, Schuurman HJ, Cooper DK
    • Journal Title

      Transplant Proc. 37(1)

      Pages: 489-490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Role of the thymus and kidney graft in the maintenance of tolerance to heart grafts in miniature swine.2005

    • Author(s)
      Mezrich JD, Benjamin LC, Sachs IA, Houser SL, Vagefi PA, Sachs DH, Madsen JC, Yamada K
    • Journal Title

      Transplantation 79(12)

      Pages: 1663-1673

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Marked prolomgation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase knockout donors and the cotransplantation of vascularized thymic tissue2005

    • Author(s)
      K.Yamada, K.Yazawa, A.Shimizu, T.Iwanaga, Y.Hisashi, DH Sachs et al.
    • Journal Title

      Nat Med 11

      Pages: 32-34

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Thrombotic Microangiopathic Glomerulopathy in Human Decay Accelerating Factor-Transgenic Swine-to-Baboon Kidney Xenografts2005

    • Author(s)
      Shimizu A, Yamada K, Yamamoto S, et al.
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 2732-2745

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Role of the thymus and kidney graft in the maintenance of tolerance to heart grafts in miniature swine.2005

    • Author(s)
      JD.Mezrich, LC Benjamin, Ja Sachs, SL.Houser, PA Vagefi, K.Yamada et al.
    • Journal Title

      Transplantation 27

      Pages: 1663-1673

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Electroporation-mediated HGF gene transfection protected the kidney against graft injury.2005

    • Author(s)
      Isaka Y, Yamada K, Takabatake Y, Mizui M, Miura-Tsujie M, Ichimaru N, Yazawa K, Utsugi R, Okuyama A, Hori M, Imai E, Takahara S
    • Journal Title

      Gene Therapy 12(10)

      Pages: 815-820

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Vascularized thymic lobe transplantation in a pig-to-baboon model: a novel strategy for xenogeneic tolerance induction and T-cell reconstitution.2005

    • Author(s)
      Yamamoto S, Lavelle JM, Vagefi PA, Arakawa H, Samelson-lones E, Moran S, Teranishi K, Kamano C, Fishman I, Awwad M, Neville DM, Shimizu A, Sykes M, Sachs DH, Yamada K
    • Journal Title

      Transplantation 80(12)

      Pages: 1783-1790

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Marked prolongation of porcine renal xenograft survival in baboons through the use of alphal,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue.2005

    • Author(s)
      Yamada K, Yazawa K, Shimizu A, Iwanaga T, Hisashi Y, Nuhn M, O'Malley P, Nobori S, Vagefi PA, Patience C, Fishman J, Cooper DK, Hawley RJ, Greenstein J, Schuurman HI, Awwad M, Sykes M, Sachs DH
    • Journal Title

      Nature Medicine 11(1)

      Pages: 32-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Marked prolongation of porcine renal xenograft survival in baboons through the use of alphal,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue2005

    • Author(s)
      Yamada K, Yazawa K, Shimizu A, et al.
    • Journal Title

      Nature Medicine 11

      Pages: 32-34

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Electroporation-mediated HGF gene transfection protected the kidney against graft injury.2005

    • Author(s)
      Isaka Y, Yamada K, Takabatake Y, Mizui M, Miura-Tsujie M, Ichimaru N, K.Yamawa K, Utsugi R, Okuyama A, Hori M, E.Imai E, Takahara S
    • Journal Title

      Gene Therapy 12

      Pages: 815-820

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Long-term acceptance of renal allografts following prenatal inoculation with adult bone marrow.2005

    • Author(s)
      Mathes DW, Solari MG, Randolph MA, Gazelle GS, Yamada K, Huang CA, Sachs DH, Lee WP
    • Journal Title

      Transplantation 80(9)

      Pages: 1300-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Electroporation-mediated HGF gene transfection protected the kidney against graft injury2005

    • Author(s)
      Isaka Y, Yamada K, Takabatake Y, et al.
    • Journal Title

      Gene Therapy 12

      Pages: 815-820

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Role of the thymus in transplantation tolerance in miniature Swine : IV. The thymus is required during the induction phase, but not the maintenance phase, of renal allograft tolerance2004

    • Author(s)
      Vagefi PA, Sachs DH, Yamada K, et al.
    • Journal Title

      Transplantation 77(7)

      Pages: 979-985

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantation.2004

    • Author(s)
      Mueller NJ, Livingston C, Knosalla C, Barth RN, Yamamoto S, Gollackner B, Dor FJ, Buhler L, Sachs DH, Yamada K, Cooper DK, Fishman JA
    • Journal Title

      J Infect Dis 1;189(9)

      Pages: 1628-1633

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Susceptibility gene for non-obstructive azoospermia in the HLA class II region : correlations with Y chromosome microdeletion and spermatogenesis.2004

    • Author(s)
      Takao T, Tsujimura A, Sada M, Goto R, Koga M, Miyagawa Y, Matsumiya K, Yamada K, Takahara S, Okuyama A
    • Journal Title

      Int J Androl 27

      Pages: 37-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Bone marrow transplantation from alpha1,3-galactosyltransferase gene-knockout pigs in baboons.2004

    • Author(s)
      Tseng YL, Dor FJ, Kuwaki K, Ryan D, Wood J, Denaro M, Giovino M, Yamada K, Hawley R, Patience C, Schuurman HJ, Awwad M, Sachs DH, Cooper DK
    • Journal Title

      Xenotransplantation 11(4)

      Pages: 361-370

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Detection of regulatory cells as an assay for allograft tolerance in miniature swine2004

    • Author(s)
      Wu A, Yamada K, Baron C, et al.
    • Journal Title

      J Heart Lung Transplant 23

      Pages: 210-217

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Regulatory T cells generated by the kidney may mediate the beneficial immune effects of combining kidney with heart transplantation2004

    • Author(s)
      Mezrich J, Yamada K, Sachs DH et al.
    • Journal Title

      Surgery 135(5)

      Pages: 473-478

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Bone marrow transplantation from alpha 1,3-galactosyltransferase gene-knockout pigs in baboons2004

    • Author(s)
      Tseng YL, Yamada K, Sachs DH et al.
    • Journal Title

      Xenotransplantation 11(4)

      Pages: 361-370

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Role of the thymus in transplantation tolerance in miniature Swine : IV. The thymus is required during the induction phase, but not the maintenance phase, of renal allograft tolerance.2004

    • Author(s)
      Vagefi PA, Ierino FL, Gianello PR, Shimizu A, Kamano C, Sachs DH, Yamada K
    • Journal Title

      Transplantation 15,77(7)

      Pages: 979-985

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] alpha 1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies2004

    • Author(s)
      Dor FJ, Yamada K, Sachs DH et al.
    • Journal Title

      Transpiantation 78(1)

      Pages: 15-20

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Detection of regulatory cells as an assay for allograft tolerance in miniature swine.2004

    • Author(s)
      Wu A, Yamada K, Baron C, Mathes DW, Monajati LM, Vagefi PA, Sachs DH
    • Journal Title

      J Heart Lung Transplant 23(2)

      Pages: 210-217

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Alpha1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies.2004

    • Author(s)
      Dor FJ, Tseng YL, Cheng J, Moran K, Sanderson TM, Lancos CJ, Shimizu A, Yamada K, Awwad M, Sachs DH, Hawley RJ, Schuurman HJ, Cooper DK
    • Journal Title

      Transplantation 15;78(1)

      Pages: 15-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Composite "thymoheart' transplantation improves cardiac aliograft survival.2004

    • Author(s)
      Menard MT, Schwarze ML, Allan JS, Johnston DR, Mawulawde K, Shimizu A, Yamada K, Houser SL, Allison KS, Sachs DH, Madsen JC
    • Journal Title

      Am J Transplat. 4(1)

      Pages: 79-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Vascularized thymic lobe transplantation in miniature swine: thymopoiesis and tolerance induction across fully MUG-mismatched barriers.2004

    • Author(s)
      Kamano C, Vagefi PA, Kumagai N, Yamamoto S, Barth RN, LaMattina JC, Moran SG Sachs DH, Yamada K
    • Journal Title

      Proc Natl Acad Sci USA 16,101(11)

      Pages: 3827-3832

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] ミニブタ心移植におけるMHCクラスII適合の重要性と免疫抑制剤短期投与の効果2004

    • Author(s)
      大津義徳, 佐田正晴, 山田和彦 他
    • Journal Title

      移植 39(5)

      Pages: 542-548

    • NAID

      10014068337

    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Regulatory mechanism of peripheral tolerance : in vitro evidence for dominant suppression of host responses during the maintenance phase of tolerance to renal allografts in miniature swine.2003

    • Author(s)
      Wu A, Yamada K, Ierino FL, Vagefi PA, Sachs DH
    • Journal Title

      Transpl Immunol. 11(3-4)

      Pages: 367-374

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Induction of tolerance to heart transplants by simultaneous cotransplantation of donor kidneys may depend on a radiation-sensitive renal-cell population2003

    • Author(s)
      Mezrich JD, Yamada K, Lee RS, et
    • Journal Title

      Transplantation 76

      Pages: 625-631

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Thymic transplantation in miniature swine : III. Induction of tolerance by transplantation of composite thymokidneys across fully major histocompatibility complex-mismatched barriers.2003

    • Author(s)
      Yamada K, Vagefi PA, Utsugi R, Kitamura H, Barth RN, LaMattina JC, Sachs DH
    • Journal Title

      Transplantation 76(3)

      Pages: 530-536

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Reduced efficacy of ganciclovir against porcine and baboon cytomegalovirus in pig-to-baboon xenotransplantation.2003

    • Author(s)
      Mueller NJ, Sulling K, Gollackner B, Yamamoto S, Knosalla C, Wilicinson RA, Kaur A, Sachs DH, Yamada K, Cooper DK, Patience C, Fishman JA
    • Journal Title

      Am J Transplant 3(9)

      Pages: 1057-1064

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model : I. Evidence for pig-specific T-cell unresponsiveness.2003

    • Author(s)
      Barth RN, Yamamoto S, LaMattina JC, Kumagai N, Kitamura H, Vagefi PA, Awwad M, Colvin RB, Cooper DK, Sykes M, Sachs DH, Yamada K
    • Journal Title

      Transplantation 75(10)

      Pages: 1615-1624

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] alThymic transplantation in miniature swine : III. Induction of tolerance by transplantation of composite thymokidneys across fully major histocompatibility complex-mismatched barriers2003

    • Author(s)
      Yamada K, Vagefi PA, Utsugi R, et
    • Journal Title

      Transplantation 76

      Pages: 530-536

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] alRegulatory mechanism of peripheral tolerance : in vitro evidence for dominant suppression of host responses during the maintenance phase of tolerance to renal allografts in miniature swine2003

    • Author(s)
      Wu A, Yamada K, lerino FL, et al.
    • Journal Title

      Transpl Immunol 11

      Pages: 367-374

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] The role of regulatory cells in miniature swine rendered tolerant to cardiac allografts by donor kidney cotransplantation.2003

    • Author(s)
      Mezrich JD, Kesselheim JA, Johnston DR, Yamada K, Sachs DH, Madsen JC
    • Journal Title

      Am J Transplant 3(9)

      Pages: 1107-1115

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] 日本医学館2003

    • Author(s)
      分担 5-4 腎移植 ブタ山田和彦
    • Journal Title

      大動物臓器移植実験マニュアル(総編集 深尾立)

      Pages: 135-135

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Journal Article] Induction of tolerance to heart transplants by simultaneous cotransplantation of donor kidneys may depend on a radiation-sensitive renal-cell population.2003

    • Author(s)
      Mezrich JD, Yamada K, Lee RS, Mawulawde K, Benjamin LC, Schwarze ML, Maloney ME, Amoah HC, Houser SL, Sachs DH, Madsen JC
    • Journal Title

      Transplantation 76(4)

      Pages: 625-631

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390387
  • [Presentation] 高度温虚血腎移植に対する22℃臓器保存の有効性-MHC確立クラウン系ミニブタを用いた体外機械灌流および腎移植モデルによる評価.2021

    • Author(s)
      有吉勇一, 関島光裕, 河合彰浩, 岩永健裕,市成ゆりか, 清水 章, 日下 守, 山田和彦, 佐原寿史
    • Organizer
      第47回日本臓器保存生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09722
  • [Presentation] Effects of static subnormothermic preservation on extended warm ischemic porcine kidneys assessed by normothermic machine perfusion and renal transplantation.2018

    • Author(s)
      Sekijima M, Ariyoshi Y, Sahara H, Kawai A, Iwanaga T, Murokawa T, Ichinari Y, Shimizu A, Kusaka M, Yamada K.
    • Organizer
      TTS2018 (27th International Congress of The Transplantation Society).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11201
  • [Presentation] 独自免疫寛容誘導療法を用いたブタ・ヒヒ間異種腎・異種肺移植-6か月以上の正常ブタ腎機能とブタ特異的免疫無反応ならびに世界最長のブタ肺生着2018

    • Author(s)
      山田和彦, 佐原寿史
    • Organizer
      第20回日本異種移植研究会
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] Histologically proven survival of porcine lung xenografts in baboons for up to 10 days using double transgenic hCD47/hCD55 GalT-KO donors2017

    • Author(s)
      Watanabe H, Sahara H, Nomura S, Tanabe T, Doi R, Ekanayake-Alper D, Boyd L, Danton M, Arn J, Hawley J, Shimizu A, Lorber M, Sykes M, Sachs D, Yamada K
    • Organizer
      14th Congress IXA (International Xenotransplantation Association 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] 臓器横断的シンポジウム7「移植後における免疫寛容の誘導」「独自の胸腺移植併用による異種腎移植と遺伝子改変による6か月以上のブタ・ヒヒ間正常異種腎機能と免疫学的抗体ドナー無反応の達成」2017

    • Author(s)
      山田和彦, 田邉 起, 佐原寿史, 関島光裕, 田﨑正行
    • Organizer
      第53回日本移植学会総会
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] Beneficial effects of hydrogen sulfide (H2S) on renal ischemia-reperfusion Injury (IRI) in CLAWN miniature swine2017

    • Author(s)
      Ariyoshi Y, Sekijima M, Sahara H, Murokawa T, Shimizu A, Yamada K
    • Organizer
      American Transplant Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10032
  • [Presentation] 臓器横断的シンポジウム7「移植後における免疫寛容の誘導」「MHC確立クラウン系ミニブタ脳死肺移植モデルを用いた新たな免疫寛容誘導戦略」2017

    • Author(s)
      佐原寿史, 岩永健裕, 関島光裕, 有吉勇一, 室川剛廣, 市成ゆりか, 清水 章, 山田和彦
    • Organizer
      第53回日本移植学会総会
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] GalT-KOブタ・霊長類間異種肺移植の成績向上2017

    • Author(s)
      佐原寿史, 渡邊洋之助, 土肥良一郎, 清水 章, 永安 武, 山田和彦
    • Organizer
      第70回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] Successful induction of tolerance of fully allogeneic lung graft with adenosine A2A receptor (A2AR) agonist in MHC-defined CLAWN miniature swine2017

    • Author(s)
      Sahara H, Sekijima M, Murokawa T, Ariyoshi Y, Iwanaga T, Ichinari Y, Shimizu A, Yamada K
    • Organizer
      American Transplant Congress 2017
    • Place of Presentation
      McCormick Place - Lakeside Center (アメリカ合衆国イリノイ州シカゴ)
    • Year and Date
      2017-04-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] GalT-KOブタ・ヒヒ間異種肺移植―早期異種移植肺廃絶の回避とその生着2017

    • Author(s)
      佐原寿史, 渡邊洋之助, 田邉起, 野村俊一郎, 清水章, 山田和彦
    • Organizer
      第19回日本異種移植研究会
    • Place of Presentation
      メルパルク京都(京都府京都市)
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] シンポジウム7「異種移植」「世界最長の GalT-KO ブタ・霊長類間異種移植肺生着への道のりと今後の課題」2017

    • Author(s)
      佐原寿史, 関島光裕, 山田和彦
    • Organizer
      第44回日本臓器保存生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] MHC確立クラウン系ミニブタを用いた慢性大動物移植実験による常温灌流保存法(NMP法: Normothermic Machine Perfusion)の有効性評価2017

    • Author(s)
      関島光裕, 有吉勇一, 佐原寿史, 岩永健裕, 室川剛廣, 市成ゆりか, 清水 章, 山田和彦
    • Organizer
      第53回日本移植学会総会
    • Data Source
      KAKENHI-PROJECT-17K11201
  • [Presentation] The beneficial role of adenosine A2A receptor agonist on tolerance induction to fully allogeneic pulmonary allograft in large animal model2017

    • Author(s)
      Sahara H, Sekijima M, Iwanaga T, Murokawa T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K
    • Organizer
      The 15th Congress of the Asian Society of Transplantation
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] MHC確立クラウンミニブタを用いたアデノシンA2A受容体アゴニスト(CGS21680)投与による移植肺免疫寛容誘導2017

    • Author(s)
      佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦
    • Organizer
      第34回日本呼吸器外科学会総会
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] Beneficial effects of hydrogen sulfide (H2S) on renal ischemia-reperfusion injury (IRI) in CLAWN miniature swine.2017

    • Author(s)
      Ariyoshi Y, Sekijima M, Sahara H, Murokawa T, Shimizu A, Yamada K.
    • Organizer
      American Transplant Congress 2017.
    • Place of Presentation
      McCormick Place - Lakeside Center(アメリカ合衆国イリノイ州シカゴ)
    • Year and Date
      2017-04-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10032
  • [Presentation] Effect of perioperative treatment with adenosine A2A receptor agonist on pulmonary allograft survival in MHC-inbred CLAWN miniature swine2017

    • Author(s)
      Sahara H, Sekijima M, Murokawa T, Ariyoshi Y, Iwanaga T, Ichinari Y, Shimizu A, Yamada K
    • Organizer
      International Society for Heart and Lung Transplantation 37th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05432
  • [Presentation] シンポジウム10. Translational Research. 「硫化水素による新規腎臓保護戦略:臨床応用に向けた大動物実験」2016

    • Author(s)
      関島光裕、佐原寿史、山田和彦
    • Organizer
      第49回日本臨床腎移植学会
    • Place of Presentation
      鳥取県米子市(米子コンベンションセンター)
    • Year and Date
      2016-03-23
    • Data Source
      KAKENHI-PROJECT-15K10032
  • [Presentation] Hydrogen sulfide prevents the kidney from ischemia-reperfusion injury in CLAWN miniature swine2016

    • Author(s)
      Sekijima M, Sahara H, Morita S, Ogawa Y, Miki K, Murokawa T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K
    • Organizer
      26th International Congress of the Transplantation Society
    • Place of Presentation
      Hong Kong ( Hong Kong Convention and Exhibition Centre)
    • Year and Date
      2016-08-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10032
  • [Presentation] 温虚血腎に対する移植前常温持続灌流の有用性-MHC確立クラウン系ミニブタを用いた慢性腎移植2016

    • Author(s)
      有吉勇一, 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦
    • Organizer
      第4回日本先進医工学ブタ研究会
    • Place of Presentation
      静岡県 三島市
    • Year and Date
      2016-10-17
    • Data Source
      KAKENHI-PROJECT-26293355
  • [Presentation] 温虚血腎に対する移植前常温持続灌流の有用性-MHC確立クラウン系ミニブタを用いた慢性腎移植.2016

    • Author(s)
      有吉勇一, 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦.
    • Organizer
      第4回日本先進医工学ブタ研究会.
    • Place of Presentation
      東レ総合研修センター(静岡県三島市)
    • Year and Date
      2016-10-17
    • Data Source
      KAKENHI-PROJECT-15K10032
  • [Presentation] Hydrogen sulfide prevents the kidney from ischemia-reperfusion injury in CLAWN miniature swine.2016

    • Author(s)
      Sekijima M, Sahara H, Morita S, Ogawa Y, Miki K, Murokawa T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K.
    • Organizer
      26th International Congress of the Transplantation Society.
    • Place of Presentation
      香港会議展覧中心(中国香港)
    • Year and Date
      2016-08-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10032
  • [Presentation] クラウンミニブタを用いた産学共同前臨床研究の成功例2015

    • Author(s)
      小林 篤、大原 絵里、三浦 清豊、徳長 靖、山﨑 彬、佐原 寿史、山田 和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
    • Place of Presentation
      鹿児島大学(鹿児島県鹿児島市)
    • Year and Date
      2015-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670630
  • [Presentation] シンポジウム2「実験用ブタ施設の現状と今後の動向」高度前臨床移植実験:医用ミニブタを用いた大動物実験として果たすべき役割と課題.2015

    • Author(s)
      山田和彦
    • Organizer
      第3回日本先進医工学ブタ研究会
    • Place of Presentation
      東京 日本大学会館
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-26293355
  • [Presentation] クラウンミニブタの医用ミニブタとしての有用性2015

    • Author(s)
      山田和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成 プロジェクト
    • Place of Presentation
      鹿児島大学(鹿児島市)
    • Year and Date
      2015-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293292
  • [Presentation] 「医用ミニブタを用いた前臨床研究」.クラウンミニブタを用いた移植モデルとMedical Gas2015

    • Author(s)
      佐原寿史、山田和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
    • Place of Presentation
      鹿児島市
    • Year and Date
      2015-03-25
    • Data Source
      KAKENHI-PROJECT-26293355
  • [Presentation] シンポジウム3「畜産研究から実験用ブタへの橋渡しおよび応用研究」高圧下過冷却状態での革新的臓器保存法-前臨床クラウン系ミニブタモデルを用いた産学共同前臨床研究2015

    • Author(s)
      小林 篤、大原絵里、三浦清豊、徳長 靖、山崎 彬、佐原寿史、山田和彦
    • Organizer
      第3回日本先進医工学ブタ研究会
    • Place of Presentation
      東京都千代田区(日本大学会館)
    • Year and Date
      2015-10-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670630
  • [Presentation] クラウンミニブタの医用ミニブタとしての有用性 -医用動物としての重要性:サイズ・MHC・遺伝子改変 性・Available reagent-2015

    • Author(s)
      山田 和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成 プロジェクト
    • Place of Presentation
      鹿児島大学(鹿児島県鹿児島市)
    • Year and Date
      2015-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670557
  • [Presentation] シンポジウム2「実験用ブタ施設の現状と今後の動向」高度前臨床移植実験:医用ミニブタを用いた大動物実験として果たすべき役割と課題2015

    • Author(s)
      山田和彦
    • Organizer
      第3回日本先進医工学ブタ研究会
    • Place of Presentation
      東京都
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25461965
  • [Presentation] シンポジウム5「実験用ブタを用いた各種応用研究」Medical Gasを用いた新たな移植医療:硫化水素の有用性2015

    • Author(s)
      佐原寿史、関島光裕、岩永健裕、市成ゆりか、山田和彦
    • Organizer
      第3回日本先進医工学ブタ研究会
    • Place of Presentation
      東京都
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25461965
  • [Presentation] Thymic transplantation to determine mechanisms of thymic involution: Insulin-like growth factor 1 receptor and forkhead box protein N1 in the thymus play a role in maintaining the juvenile thymus.2015

    • Author(s)
      ekijima M, Tasaki M, Sahara H, Shimizu A, Yamada K
    • Organizer
      The 14th Congress of the Asian Society of Transplantation
    • Place of Presentation
      Singapore
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293292
  • [Presentation] 臓器横断的ワークショップ1「臓器移植における新規技術・機器の導入」高圧下過冷却状態での革新的臓器保存法-前臨床クラウン系ミニブタモデルによる開発2015

    • Author(s)
      佐原寿史、関島光裕、三浦宏平、河合昭浩、脇 詩織、岩永健裕、市成ゆりか、清水 章、山田和彦
    • Organizer
      第51回日本移植学会総会
    • Place of Presentation
      熊本県熊本市(ホテル日航熊本)
    • Year and Date
      2015-10-01
    • Data Source
      KAKENHI-PROJECT-26670630
  • [Presentation] クラウンミニブタの医用ミニブタとしての有用性 -医用動物としての重要性:サイズ・MHC・遺伝子改変性・Available reagent-2015

    • Author(s)
      山田 和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
    • Place of Presentation
      鹿児島大学(鹿児島県鹿児島市)
    • Year and Date
      2015-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670630
  • [Presentation] クラウンミニブタを用いた産学共同前臨床研究の成功例2015

    • Author(s)
      小林 篤、大原 絵里、三浦 清豊、徳長 靖、山﨑 彬、佐原 寿史、山田 和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成 プロジェクト
    • Place of Presentation
      鹿児島大学(鹿児島県鹿児島市)
    • Year and Date
      2015-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670557
  • [Presentation] MHC-inbred CLAWN miniature swine as preclinical large animal model for transplantation.2015

    • Author(s)
      Sahara H, Iwanaga T, Sekijima M, Waki S, Ichinari Y, Shimizu A, Yamada K
    • Organizer
      The 14th Congress of the Asian Society of Transplantation.
    • Place of Presentation
      Singapore
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293355
  • [Presentation] シンポジウム2「実験用ブタ施設の現状と今後の動向」高度前臨床移植実験:医用ミニブタを用いた大動物実験として果たすべき役割と課題2015

    • Author(s)
      山田和彦
    • Organizer
      第3回日本先進医工学ブタ研究会
    • Place of Presentation
      東京都
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-26293292
  • [Presentation] シンポジウム5「実験用ブタを用いた各種応用研究」Medical Gasを用いた新たな移植医療:硫化水素の有用性.2015

    • Author(s)
      佐原寿史、関島光裕、岩永健裕、市成ゆりか、山田和彦
    • Organizer
      第3回日本先進医工学ブタ研究会
    • Place of Presentation
      東京 日本大学会館
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-26293355
  • [Presentation] 「臨床医としての医用ミニブタを用いた研究」.腎移植医療の問題点とその対策2015

    • Author(s)
      日下 守、佐原寿史、関島光裕、山田和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
    • Place of Presentation
      鹿児島市
    • Year and Date
      2015-03-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293355
  • [Presentation] シンポジウム「肺移植の現況と将来展」GalT-KO ブタ・カニクイザル間異種肺移植実験の現状 -異種腎臓移植との比較による治療標的の解明と対策2014

    • Author(s)
      佐原寿史, 山田和彦
    • Organizer
      第31回日本呼吸器外科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] シンポジウム「肺移植の現況と将来展」GalT-KOブタ・カニクイザル間異種肺移植実験の現状 - 異種腎臓移植との比較による治療標的の解明と対策.2014

    • Author(s)
      佐原寿史、山田和彦
    • Organizer
      第31回日本呼吸器外科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Establishment of clinically applicable strategy of CO therapy - Beneficial effects of inhaled carbon monoxide to brain-dead donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine.2014

    • Author(s)
      Sahara H, Miura K, Waki S, Kawai A, Shimizu A, Yamada K
    • Organizer
      World Transplant Congress 2014.
    • Place of Presentation
      San Francisco, CA, US
    • Data Source
      KAKENHI-PROJECT-25461965
  • [Presentation] MHC 確立クラウンミニブタ小腸移植手技の工夫2014

    • Author(s)
      三浦宏平, 佐原寿史, 河合昭浩, 脇 詩織, 清水 章, 山田和彦
    • Organizer
      第114回日本外科学会定期学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23390314
  • [Presentation] Attenuation of hyperacute dysfunction and microangiopathy by the treatment of carbon monoxide in GalT-KO pulmonary xenotransplantation2013

    • Author(s)
      Sahara H, Nagashima H, Miura K, Waki S, Kawai A, Nakano K, Matsunari H, Arai Y, Sekijima M, Tasaki M, Setoyama K, Shimizu A, Date H, Yamada K
    • Organizer
      12th Congress IXA (International Xenotransplantation Association 2013)
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Beneficial effects of inhaled carbon monoxide (CO) to brain-dead (BD) donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine.2013

    • Author(s)
      Miura K, Sahara H, Waki S, Kawai A, Shimizu A, Yamada K
    • Organizer
      The 13th Congress of the Asian Society of Transplantation.
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-25461965
  • [Presentation] Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation.2013

    • Author(s)
      Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
    • Organizer
      The 13th Congress of the Asian Society of Transplantation
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Attenuation of hyperacute dysfunction and microangiopathy by the treatment of carbon monoxide in GalT-KO pulmonary xenotransplantation2013

    • Author(s)
      Kawai A, Nakano K, Matsunari H, Arai Y, Sekijima M, Tasaki M, Setoyama K, Shimizu A, Date H, Yamada K
    • Organizer
      12th Congress IXA (International Xenotransplantation Association 2013).
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Carbon monoxide (CO) inhalation prolongs survival of the fully MHC-disparate lung graft from brain death donors in miniature swine2013

    • Author(s)
      Sahara H, Miura K, Kawai A, Waki S, Sekijima M, Shimizu A, Yamada K
    • Organizer
      International Society for Heart and Lung Transplantation 33rd Annual Meeting
    • Place of Presentation
      モントリオール
    • Data Source
      KAKENHI-PROJECT-24659637
  • [Presentation] Beneficial effects of inhaled carbon monoxide (CO) to brain-dead (BD) donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine2013

    • Author(s)
      Miura K, Sahara H, Waki S, Kawai A, Shimizu A, Yamada K
    • Organizer
      The 13th Congress of the Asian Society of Transplantation
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-24659637
  • [Presentation] Carbon monoxide (CO) inhalation prolongs survival of the fully MHC-disparate lung graft from brain death donors in miniature swine2013

    • Author(s)
      Sahara H, Miura K, Kawai A, Waki S, Sekijima M, Shimizu A, Yamada K
    • Organizer
      International Society for Heart and Lung Transplantation 33rd Annual Meeting
    • Place of Presentation
      Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-24659637
  • [Presentation] Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation2013

    • Author(s)
      Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
    • Organizer
      The 13th Congress of the Asian Society of Transplantation
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] シンポジウム2「各系統実験用ブタ紹介」MHC確立クラウン系ミニブタを用いた同種移植実験2013

    • Author(s)
      佐原寿史、岩永健裕、山田和彦
    • Organizer
      第1回日本先進医工学ブタ研究会
    • Place of Presentation
      大阪市
    • Year and Date
      2013-11-12
    • Data Source
      KAKENHI-PROJECT-24659637
  • [Presentation] High-Mobility Group Box-1 as a novel therapeutic target for reducing pulmonary ischemia-reperfusion injury in CLAWN miniature swine.2012

    • Author(s)
      Sahara H, Shimizu A, Sekijima M, Setoyama K, Oku M, Nishimura H, Yamada K
    • Organizer
      24th International Congress of the Transplantation Society
    • Place of Presentation
      Berlin
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] シンポジウム4「臓器保存から臓器蘇生へ-温度を考える」Strategies to reduce ischemia-reperfusion injury (IRI) for expansion of usage of marginal donor organs in a preclinical large animal model of CLAWN miniature swine2012

    • Author(s)
      山田和彦
    • Organizer
      第39回日本低温医学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390314
  • [Presentation] Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation.2012

    • Author(s)
      Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
    • Organizer
      24th International Congress of the Transplantation Society
    • Place of Presentation
      Berlin
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] GalT-KO ブタ肺による急性期グラフト機能不全抑制効果の体外循環肺移植モデルによる評価2012

    • Author(s)
      佐原寿史, 清水 章, 関島光裕, 田崎正行, 瀬戸山健太郎, 長嶋比呂志, 伊達洋至, 山田和彦
    • Organizer
      第29回日本呼吸器外科学会総会
    • Place of Presentation
      秋田市
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Protective effect of anti-high-mobility group box-1 (HMGB1) antibody on pulmonary ischemia-reperfusion injury in miniature swine.2012

    • Author(s)
      Sahara H, Shimizu A, Sekijima M, Setoyama K, Oku M, Nishimura H, Yamada K
    • Organizer
      International Society for Heart and Lung Transplantation 32nd Annual Meeting
    • Place of Presentation
      Prague
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Carbon monoxide administered only to the donor is sufficient to prolong pulmonary allograft survival across a fully MHC-mismatched barrier in CLAWN miniature swine.2012

    • Author(s)
      Sahara H, Sekijima M, Tasaki M, Oku M, Nishimura H, Iwanaga T, Iwanaga T, Sekijima A, Setoyama K, Shimizu A, Yamada K
    • Organizer
      24th International Congress of the Transplantation Society
    • Place of Presentation
      Berlin
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] High-mobility group box 1(HMGB1)が腎虚血再灌流障害(IRI)進展に及ぼす役割の大動物モデルによる解明2012

    • Author(s)
      三浦宏平、佐原寿史、関島光裕、河合昭浩、脇詩織、清水章、山田和彦
    • Organizer
      第48回日本移植学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23390314
  • [Presentation] 教育講演II.大動物を用いた前臨床虚血再灌流傷害モデルの作成とマージナルドナー臓器活用戦略2012

    • Author(s)
      山田和彦
    • Organizer
      第39回日本臓器保存生物医学会学術集会
    • Place of Presentation
      福島
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390314
  • [Presentation] The thymus is required to break tolerance of renal allografts in a miniature swine model2012

    • Author(s)
      Villani V, Yamada K et al
    • Organizer
      24th International Congress of the Transplantation Society
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-22390249
  • [Presentation] Donor preconditioning with carbon monoxide (CO) prolongs lung graft survival in miniature swine.2012

    • Author(s)
      Sahara H, Shimizu A, Tasaki M, Sekijima M, Oku M, Nishimura H, Iwamoto E, Setoyama K, Yamada K
    • Organizer
      International Society for Heart and Lung Transplantation 32nd Annual Meeting
    • Place of Presentation
      Prague
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Prevention of hyper-acute pulmonary xenograft dysfunction using GalT-KO swine in an ex-vivo lung perfusion model2011

    • Author(s)
      Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
    • Organizer
      CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress
    • Place of Presentation
      Miami beach, FL, US
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] シンポジウム2.次世代の移植医療に向けて:先端技術を応用した移植医療の開発「臨床応用を目指したブタ・サル間異種移植実験」2011

    • Author(s)
      佐原寿史、長嶋比呂志、齋藤敏樹、島津美樹、伊達洋至、清水章、山田和彦
    • Organizer
      第47回日本移植学会総会
    • Place of Presentation
      仙台市
    • Year and Date
      2011-10-06
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Prevention of hyper-acute pulmonary xenograft dysfunction using GalT-KO swine in an ex-vivo lung perfusion model2011

    • Author(s)
      Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K
    • Organizer
      CTS (Cell Transplant Society)-IXA (International Xenotransplantation Association) 2011 Joint Congress
    • Place of Presentation
      マイアミビーチ
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Xenotranplantation : Kidney, Islets, Heart and Liver Which Clinical Trial Should Start First?2011

    • Author(s)
      山田和彦
    • Organizer
      第8回北関東甲信越肝移植談話会
    • Place of Presentation
      東京
    • Year and Date
      2011-01-15
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 体外循環回路を用いたEx-vivo GalT-KOブタ肺移植モデルによる急性期グラフト機能不全抑制効果の評価2011

    • Author(s)
      佐原寿史、清水章、関島光裕.田崎正行、瀬戸山健太郎.長嶋比呂志、伊達洋至、山田和彦
    • Organizer
      第64回日本胸部外科学会定期学術集会
    • Place of Presentation
      名古屋市
    • Year and Date
      2011-10-10
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] SOTA 6- Barriers to vascularized xenotransplantation solid organ Xenotransplantation: Overcome cellular immune responses.2011

    • Author(s)
      Yamada K.
    • Organizer
      CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress.
    • Place of Presentation
      Miami beach, FL, US.
    • Data Source
      KAKENHI-PROJECT-22591417
  • [Presentation] シンポジウム2.次世代の移植医療に向けて : 先端技術を応用した移植医療の開発「臨床応用を目指したブタ・サル間異種移植実験」2011

    • Author(s)
      佐原寿史, 長嶋比呂志, 齋藤敏樹, 島津美樹, 伊達洋至, 清水 章, 山田和彦
    • Organizer
      第47回日本移植学会総会
    • Place of Presentation
      仙台市
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] Strategies to resolve the organ shortage : Xenotransplantation using transgenic/gene knockout technology2010

    • Author(s)
      山田和彦
    • Organizer
      2010 JUNBA SYMPOSIUM
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2010-01-12
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Strategies to resolve the organ shortage : Xenotransplantation using transgenic/gene knockout technology2010

    • Author(s)
      山田和彦
    • Organizer
      ATC (American Transplantation Society) 2010
    • Place of Presentation
      San Francisco
    • Year and Date
      2010-01-12
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 臨床応用を視野に入れた臓器置換最先端戦略:異種移植はここまで来ている"世界・ハーバード大学・鹿児島大学"2010

    • Author(s)
      山田和彦
    • Organizer
      第37回日本臓器保存生物医学会学術集会
    • Place of Presentation
      新潟
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] ブタ・サル異種間膵島移植:クラウンブタ膵島異種移植後2ヶ月間の正常血糖維持2010

    • Author(s)
      田崎正行、山田和彦, 他
    • Organizer
      第46回日本移植学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] ブタ・サル異種間膵島移植:クラウン系ミニブタ膵島移植後2ヶ月間の正常血糖維持2010

    • Author(s)
      山田和彦
    • Organizer
      日本膵・膵島移植研究会
    • Place of Presentation
      宇都宮
    • Year and Date
      2010-03-12
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Hepatocyte Growth Factor regimen in a life supporting xenogeneic islet transplantation CLAWN miniature swine-to -cynomologous monkey model.2010

    • Author(s)
      Yamada K, Nishimura H, Sahara H., et al
    • Organizer
      XXIII International Congress of Transplantation Society
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] ワークショップ3.膵・膵島移植の現状と今後の課題」血管再構築と免疫寛容誘導戦略に基づく重症糖尿病性腎症根治療法の確立2010

    • Author(s)
      山田和彦
    • Organizer
      第46回日本移植学会総会
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-22591417
  • [Presentation] ワークショップ:血管再構築と免疫寛容誘導戦略に基づく重症糖尿病性腎症根治療法の確立2010

    • Author(s)
      山田和彦、佐原寿史
    • Organizer
      第46回日本移植学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] α1, 3ガラクトース転移酵素遺伝子ダブルノックアウトブタの体細胞クローニングにおける Scriptaid の効果2010

    • Author(s)
      松成ひとみ, 池澤有加, 渡邊将人, 梅山一大, 中野和明, 藤原主, 竹内靖浩, 本田香澄, 前原美樹, 高柳就子, 山田和彦, 宮川周士, 長嶋比呂志
    • Organizer
      第13回日本異種移植研究会
    • Place of Presentation
      東京都
    • Year and Date
      2010-03-14
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 国内初のミニブタ(NIBS系)をクローン胚移植用レシピエントとしたGalT-KOミニブタの作出とそのブタ腎を用いたGalT-KOブタ・サル異種間腎移植2010

    • Author(s)
      山田和彦
    • Organizer
      第46回日本移植学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-21
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Hepatocyte Growth Factor regimen in a life supporting xenoegeneic islet transplantation CLAWN miniature swine-to-cynomologous monkey model.2010

    • Author(s)
      Yamada K, Oku M, et al.
    • Organizer
      XXIII International Congress of Transplantation Society
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-22591411
  • [Presentation] GalKOブタ・ヒヒ間異種Thymokidney移植における導入期至摘CD3+T細胞数の検討2010

    • Author(s)
      西村博昭、山田和彦, 他
    • Organizer
      第46回日本移植学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] ブタ・サル異種間膵島移植 : クラウン系ミニブタ膵島移植後2ヶ月間の正常血糖維持2010

    • Author(s)
      山田和彦
    • Organizer
      日本膵・膵島移植研究会
    • Year and Date
      2010-03-12
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] High levels of cytotoxic anti-non Gal preformed natural antibody did not induce hyperacute rejection but did cause early graft loss in a GalT-KO pig-to-baboon thymokidney model.2010

    • Author(s)
      Nishimura H, Yamada K, et al.
    • Organizer
      XXIII International Congress of Transplantation Society
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] GalKOブタ・ヒヒ間異種Thymokidney移植における導入期至摘CD3+T細胞数の検討2010

    • Author(s)
      西村博昭、山田和彦
    • Organizer
      第62回日本泌尿器科学会西日本総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Optimal T cell depletion is essential for successful thymokidney transplants in GalT-KO pig to baboon model.2010

    • Author(s)
      Yamada K, Nishimura H, et al.
    • Organizer
      XXIII International Congress of Transplantation Society
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 国内初のミニブタ(NIBS系)をクローン胚移植用レシピエントとしたGa1T-KOミニブタの作出とそのブタ腎を用いたGa1T-KOブタ・サル異種間腎移植2010

    • Author(s)
      山田和彦
    • Organizer
      日本異種移植研究会
    • Place of Presentation
      東京都
    • Year and Date
      2010-03-14
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 遺伝子組換え異種臓器:独自の免疫寛容誘導療法による異種移植の臨床応用への試み2010

    • Author(s)
      山田和彦
    • Organizer
      第62回日本泌尿器科学会西日本総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Life-Supporting GalTKO Swine Kidney Xenografts.2010

    • Author(s)
      山田和彦
    • Organizer
      2010 Seoul Forum on Xenotransplantation
    • Place of Presentation
      Seoul, South Korea
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 国内初のミニブタ (NIBS 系) をクローン胚移植用レシピエントとした GalT-KO ミニブタの作出とそのブタ腎を用いた GalT-KO ブタ・サル異種間腎移植2010

    • Author(s)
      山田和彦
    • Organizer
      日本異種移植研究会
    • Year and Date
      2010-03-14
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Hepatocyte Growth Factor regimen in a life supporting xenoegeneic islet transplantation CLAWN miniature swine-to-cynomologous monkey model.2010

    • Author(s)
      Yamada K, Oku M, et al.
    • Organizer
      XXIII International Congress of Transplantation Society
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] クラウン系ミニブタを用いた移植試験の現状2009

    • Author(s)
      山田 和彦
    • Organizer
      日本異種移植研究会
    • Place of Presentation
      鹿児島市
    • Year and Date
      2009-03-07
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Life Supporting Xenogeneic Islet Transplantation with a Regimen Including Hepatocyte Growth Factor in a CLAWN Miniature Swine-to-Cynomologous Monkey Model2009

    • Author(s)
      Kazuhiko Yamada
    • Organizer
      IPITA-IXA Joint Congress 国際膵臓・膵島移植・異種移植合同学会
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] シンポジウム免疫寛容膵島移植免疫寛容誘導の独自戦略:Strategy to Induce Tolerance to Islets2009

    • Author(s)
      山田和彦
    • Organizer
      第45回日本移植学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] レクチンブロット法によるαGa1-knockout ブタの糖鎖抗原の解析2009

    • Author(s)
      山本亜紀, 徐恒傑, 武石俊作, 山田正雄, 三善英知, 池田孔佑, 松成ひとみ, 長嶋比呂志
    • Organizer
      第45回日本移植学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2009-09-16
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Lectin microarray analyses of endothelial cells and fibroblasts from the α1, 3 galactosyltransferase knockout pig2009

    • Author(s)
      Miyagawa S, Yamamoto A, Ikeda K, Matsunari H, Nagashima H, Takeishi S, Yamada M, Fukuzawa M
    • Organizer
      IPITA-IXA
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Strategy to Induce Tolerance to Islets across Allogeneic/Xenogeneic Barriers2009

    • Author(s)
      山田和彦
    • Organizer
      2009 Joint Conference of 10th CTS(Cell Transplant Society)and 36th JSOPMB(Japan Society for Organ Preservation and Medical Biology)
    • Place of Presentation
      Okayama, Japan
    • Year and Date
      2009-04-20
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Life Supporting Xenogeneic Islet Transplantation with a Regimen Including Hepatocyte Growth Factor in a CLAWN Miniature Swine-to-Cynomologous Monkey Model2009

    • Author(s)
      山田和彦
    • Organizer
      IPITA-IXA Joint Congress
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] シンポジウム:I型糖尿病移植治療の現況と展望 -膵移植vs.膵島移植 異種移植を用いた糖尿病根治の展望2009

    • Author(s)
      山田和彦
    • Organizer
      日本外科学会総会
    • Place of Presentation
      博多
    • Year and Date
      2009-04-02
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] The Role of Primates in Translational Research2008

    • Author(s)
      Yamada Kazuhiko
    • Organizer
      X X II International Congress of The Transplantation Society
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-08-09
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Presentation] Update on outcome of life-supporting xenogeneic GalTKO organs and strategies that may be required in addition to GalTKO2008

    • Author(s)
      山田 和彦
    • Organizer
      第11回日本異種移植研究会
    • Place of Presentation
      大阪
    • Year and Date
      2008-02-23
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Hepatocyte Growth Factor sustains the Treg population and prolongs survival of kidney allografts in MHC-inbred CLAWN Miniature Swine2008

    • Author(s)
      Oku manei [演題責任者 : Kazuhiko Yamada]
    • Organizer
      American Society of Nephrology Renal Week 2008
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Presentation] Life-Supporting GalTKO Swine Kidney Xenografts2008

    • Author(s)
      Yamada Kazuhiko
    • Organizer
      XXII International Congress of The Transplantation Society
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-08-13
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Life-Supporting GalTKO Swine Kidney Xenografts.2008

    • Author(s)
      山田和彦
    • Organizer
      XXII International Congress of The Transplantation Society
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-08-13
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 異種移植2008

    • Author(s)
      山田和彦
    • Organizer
      第44回日本移植学会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2008-09-21
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Life-Supporting GalT-KO Swine Kidney Xenografts2008

    • Author(s)
      Kazuhiko Yamada
    • Organizer
      XXII International Congress of The Transplantation Society
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-08-13
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] The Role of Primates in Translational Research2008

    • Author(s)
      Yamada Kazuhiko
    • Organizer
      XXII International Congress of The Transplantation Society
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-08-09
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] The Role of Primates in Translational Research2008

    • Author(s)
      Yamada Kazuhiko
    • Organizer
      XXII International Congress of The Transplantation Society
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-08-09
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Presentation] Maintenance of Treg Population and Prolongation of Allograft Survival by Hepatocyte Growth Factor in MHC-inbred CLAWN Miniature Swine2008

    • Author(s)
      Oku Manei (共同演者 : Masaharu Sada) [演題責任者 : Kazuhiko Yamada]
    • Organizer
      X X II International Congress of The Transplantation Society
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-08-11
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Presentation] MHC inbred クラウン系ミニブタ腎虚血再灌流モデルにおける血清サイトカイン動態2008

    • Author(s)
      西村博昭[演題責任者:山田和彦]
    • Organizer
      第44回日本移植学会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2008-09-21
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Presentation] Composite thymo-islet-kidneys induce tolerance and cure surgically induced diabetes2007

    • Author(s)
      Griesemer A, Hirakata A, Okumi M, Shimizu A, Etter J, Sachs DH, Yamada K
    • Organizer
      CTS-IPITA-IXA 2007 Joint Conference
    • Place of Presentation
      Minneapolis, USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Xenogeneic thymokidney transplantation using GalT-KO swine produced by conventional breeding.2007

    • Author(s)
      Griesemer A, Hirakata A, Arn S, Shimizu A, Duggan M, Hanekamp J, Moran SG, Sachs DH, Yamada K.
    • Organizer
      CTS-IPITA-IXA 2007 Joint Conference
    • Place of Presentation
      Minneapolis, USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 国産MHC inbredミニブタ同種間腎移植での慢性拒絶反応モデルの確立2007

    • Author(s)
      奥見雅由、屋万栄、佐原寿史、清水章、佐田正晴、山田和彦
    • Organizer
      第43回日本移植学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-23
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 国産MHC inbredミニブタ同種間膵島移植モデルにおける機能性膵島移植の初めての成功2007

    • Author(s)
      屋万栄、奥見雅由、佐原寿史、清水章、山田和彦
    • Organizer
      第43回日本移植学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Importance of T cell tolerance induction for controlling xenogeneic cellular rejection2007

    • Author(s)
      Kazuhiko Yamada Invited (Workshop)
    • Organizer
      ATC 2007 (America Transplantation Congress)
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2007-05-07
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Composite islet-kidneys from single donors cure diabetes across fully allogeneic barrier in nonhuman primates2007

    • Author(s)
      Hirakata A, Griesemer A, Tchipashvili V, Shimizu A, Sachs DH, Yamada K
    • Organizer
      CTS-IPITA-IXA 2007 Joint Conference
    • Place of Presentation
      Minneapolis, USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Composite islet-kidneys from single donors cured diabetes in nonhuman primates (NHP baboons) across fully allogenic barrier2007

    • Author(s)
      平方敦史、Adam Griesemer、奥見雅由、清水章、山田和彦
    • Organizer
      第43回日本移植学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] Vascularized thymic grafts induce transplantation tolerance in large animal models2007

    • Author(s)
      Kazuhiko Yamada
    • Organizer
      CTS-IPITA-IXA 2007 Joint Conference
    • Place of Presentation
      Minneapolis, USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-19209043
  • [Presentation] 国産MHC inbredミニブタ同種間腎移植での慢性拒絶反応モデルの確立2007

    • Author(s)
      奥見雅由、屋万英、佐原寿史、清水章、佐田正晴、山田和彦
    • Organizer
      日本移植学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-23
    • Data Source
      KAKENHI-PROJECT-19390422
  • [Presentation] Recent progress in major research laboratories in East Asia - Preclinical study - “Preclinical large animal xenotransplantation projects in Kagoshima”

    • Author(s)
      Sahara H, Yamada K
    • Organizer
      The 2nd Symposium of the East Asia Xenotransplantation Association
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-23390337
  • [Presentation] パネルディスカッション「ブタを用いたイノベーティブな用途研究」.ミニブタを用いた前臨床研究推進のための研究・教育拠点形成プロジェクト

    • Author(s)
      山田和彦
    • Organizer
      第2回日本先進医工学ブタ研究会
    • Place of Presentation
      東レ総合研修センター(静岡県三島市)
    • Year and Date
      2014-10-24 – 2014-10-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293292
  • [Presentation] 「医用ミニブタを用いた前臨床研究」.クラウンミニブタを用いた移植モデルとMedical Gas

    • Author(s)
      佐原寿史、山田和彦
    • Organizer
      第3回公開シンポジウム先進医用ミニブタの開発と前臨床研究拠点形成プロジェクト
    • Place of Presentation
      鹿児島市
    • Year and Date
      2015-03-24 – 2015-03-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461965
  • 1.  SAHARA Hisashi (90452333)
    # of Collaborated Projects: 21 results
    # of Collaborated Products: 75 results
  • 2.  SHIMIZU Akira (00256942)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 60 results
  • 3.  SEKIJIMA Mitsuhiro (20568589)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 19 results
  • 4.  NOBORI Shuji (30433288)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  HIRAKATA Atsushi (40468765)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  NAGASHIMA Hiroshi (50318664)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 7.  SADA Masaharu (20162399)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 8.  OKU Manei (50550000)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 9.  Kusaka Mamoru (40309141)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 10.  野崎 剛 (00433087)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  ODAN Hideki (10363061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OKITSU Teru (10378672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  SAITO Toshiki (00162214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SATO Masahiro (30287099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KAMIMURA Ryozo (30253884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOSHIMURA Norio (00191643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  DATE Hiroshi (60252962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 18.  HOSHINAGA Kiyotaka (30229174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  FUJISATO Toshiya (60270732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TAKAHARA Shiro (70179547)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 21.  ARIYOSHI Yuichi (10643520)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 22.  NISHIMURA Masahiro (00294570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  坪内 博仁 (60145480)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  瀬戸山 健太郎 (00372805)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OTA Masao (50115333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  ANDO Asako (40101935)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  石井 正和 (00456683)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  朝比奈 泉 (30221039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  小戝 健一郎 (90258418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  岩永 健裕 (40518916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  KOBAYASHI Atsushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 32.  MIURA Kouhei
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 33.  KAWAI Akihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 34.  WAKI Shiori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 35.  安藤 麻子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi