TANAKA Noriaki 田中紀章

Researcher Number	10127566
Other IDs
External Links
Affiliation (Current)	2019: 岡山大学, 医歯薬学総合研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2010: 岡山大学, 大学院・医歯薬学総合研究科, 教授 2005 – 2008: Okayama University, Graduate School of Medicine. Dentistry and Pharmaceutical Sciences, Professor, 大学院・医歯薬学総合研究科, 教授 2006: Okayama University, Graduate School of Medicine Dentistry and Pharmaceutical Sdences, Professor, 大学院医歯薬学総合研究科, 教授 2001 – 2004: Okayama University, Graduate School of Medicine and Dentistry, Professor, 大学院・医歯学総合研究科, 教授 1999 – 2001: 岡山大学, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator General surgery / General surgery / Thoracic surgery / Digestive surgery / Digestive surgery Except Principal Investigator General surgery / Digestive surgery / Digestive surgery / Thoracic surgery / Functional basic dentistry / Pathological medical chemistry / Gastroenterology / Laboratory medicine
Keywords	Principal Investigator E2F-4 / microsatellite instability / genetic instability / 大腸癌 / Colon cancer / epigenetic alteration / gastroenterological cancer / colorectal cancer / carcinogenesis / lymphokine activated killer … More Except Principal Investigator microsatellite instability / 大腸癌 / genetic instability / E2F-4 / epigenetic alteration / ヘパラナーゼ / 浸潤 / colorectal cancer / carcinogenesis / heparanase / Surfactant protein A / invasion / 転移 / スクリーニング / Fas / FK506 / IFN-α / LAK cell / Thyroid transcription factor 1 / 門脈内注入 / 免疫抑制 / Thyriod transcription factor 1 / NF-κB / gastroenterological cancer / pancreatic cancer / choemoterapy / グルココルチコイド / ノイラミニダーゼ / インターロイキン2 / neuraminidase / 血管新生 / Colon cancer / BRAF / genetic alteration / 小腸移植 / 分化 / MSH3 / metastasis / TTF1 / interleukin 2 / esophageal cancer / TNF / 肺癌 / polymorphism / serum DNA / gastric cancer / LAK細胞 / メチル化 / COX-2 / 過冷却保存 / 可逆性不死化細胞 / 制限増殖アデノウイルス / cisplatin / epitenetics / Gefitinib / 軟骨細胞 / differentiation / 肝癌 / 遺伝子複製異常 / KRas / transplant organ storage / 化学療法 / microsatellite inslability / 抗腫瘍活性 / サイトカインクロストーク / プロモータ / non small cell lung cancer / 抗氷晶核蛋白 / Serum ammonia level / DNA repair / plasma / intratracheal administration / インドメサシン / apoptosis / 肝移植 / NF-kB / 癌 / ornihine decarboxylase (0DC) / 肝細胞スフェロイド / 腫瘍検査学 / 肝硬変 / サイクロスポリンA / CAG繰り返し配列 / 転移性肝癌 / Pig / Liver failure / 非特異的キラーリンパ球 / ascorbic acid 2-glucoside / 再生治療 / 質量分析計 / 早期診断 / hepatic regeneration / レクチン固定セファロース粒子 / DNA修復異常 / 門脈内投与 / Circulating culture / 腫瘍壊死因子 / 類洞内皮細胞 / 臓器保存 / 末梢血 / IL-2徐放製剤 / マトリックス / 過冷却 / NK細胞 / 骨芽細胞 / アルブミン産生 / DNAチップ / supercooling preservation / cold preservation injury / 体外循環システム / 小腸 / IL-2 slow delivery system / esophagealcancer / ascorbic acid / 不死化機構 / Artificail liver support / 部分肝切除 / hTERT / 肝再生 / Thyroid transcription factor / 進行肺癌 / LOII / 活性化キラー細胞 / 遺伝子不安定化 / 悪性度 / TNF-α / DNAメチル化 / methylation / ゲノム / 抗腫瘍性キラーリンパ球 / 発現プロファイル / transplantation / 特異的キラーTリンパ球 / 遺伝子解析 / ascorbic acid-2-glucoside / repair / トランスレーショナルリサーチ / drug sensitivitv / drug sensitivity / 消化器癌 / スフェロイド / 肝部分切除 / ヒト肝細胞 / malignant degree / エピジェネティックス / surfactant protein / metastatic liver cancer / 肝不全 / 遺伝子治療 / アポトーシス / アンモニア処理能 / 臨床 / adenovirus / 肺胞サーファクタントプロティンA / 便潜血反応 / peripheral blood / 遺伝子診断 / DNA / gastrointestinal neoplasia / Lung cancer / 尿素合成 / intraportal injection / colon cancer / 間葉系幹細胞 / ラット / アスコルビン酸 / テロメラーゼ / NK cell / ILー2 / 人工肝臓 / eni genetics / epigenetics / 肺胞サーファクタント / 癌悪性化機構 / アンモニア除去 / 移植 / マイクロサテライト不安定性 / 移植臓器保存 / Immunosuppression / anti-freezing protein / LOH / subzero nonfreezing preservation / 膵癌 / rat / プロテオーム解析 / Glucocorticoid / 急性肝不全 / genetic diagnosis / gastrointestinal neoplasea / liver transplantation / ブタ / ペパラナーゼ / 発癌 / 冷保存傷害 / 脂肪細胞 / 胃癌 / 遺伝子 / 劇症肝炎 / cytokine cross-talk / promoter / anaiogenesis / 乳癌 / 抗凍結性蛋白 / cyclosporine A / 検便 / anti-nucleating protein / 連続培養 / indomethacin / gastic cancer / small intestine / Spheroid / 循環培養 / liver cirrhosis / angiogenesis / 血漿 / 再生医療 Less

Targeting advanced non small cell lung cancer in vivo by pulmonary surfactant -adenovirus-mediated gene transfer
- Principal Investigator
  
  MATSUOKA Jyunji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
Development of Non-invasive Screening Tool to Detect Colorectal Neoplasia.
- Principal Investigator
  
  NAGASAKA Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
Hepatic differentiation of human embryonic stem cells and its application to the development of a bioartificial liver systemPrincipal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Development of epigenetic biomarker for early diagnosis of gastrointestinal cancer
- Principal Investigator
  
  MATSUBARA Nagahide
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
第三世代制限増殖ウイルスベクターを用いた瀰漫性胸膜中皮腫に対する新規治療法の開発Principal Investigator
- Principal Investigator
  
  田中紀章
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
Functional Analysis of Heparanase-Development of Therapeutic Modalities for Antiangiogenesis and Defferentiation-
- Principal Investigator
  
  NAOMOTO Yoshio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
HUMAN NON-SMALL CELLLUNG CANCER TARGETED PROMOTER SYSTEM FOR GENE THERAPY
- Principal Investigator
  
  MATSUOKA Junji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
Elucidation, of the interacting mechanism between epigenetic and genetic alterations in gastrointestinal cancers and of the possible application to the clinicPrincipal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Investigation of colorectal carcinogenesis for genetic diagnosis
- Principal Investigator
  
  KAMBARA Takeshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Inhibition of cancer invasion and metastasis targeting heparanase
- Principal Investigator
  
  NAOMOTO Yoshio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
間葉系幹細胞の遺伝子発現プロファイル解析と硬組織再生への応用
- Principal Investigator
  
  大山和美, NAKANISHI Toru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Okayama University
Development of Regenerative Medicine Using Reversibly Proliferating Human Bone Marrow Mesenchymal Stem CellsPrincipal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  OKAYAMA UNIVERSITY
Elucidation of new molecular mechanism of cancer caused by gene promoter methylation and its clinical aplication
- Principal Investigator
  
  MATSUBARA Nagahide
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  OKAYAMA UNIVERSITY
可逆性不死化ヒト肝細胞を用いたプロテオーム解析による不死化機構の研究
- Principal Investigator
  
  米澤一仁
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Bioartificial liver development using reversibly immortalized human liver cell lines.Principal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Study of the mechanisms of the induction of hyporesponsiveness by intraportal infusion of donor cells by using GFP rats
- Principal Investigator
  
  MATSUOKA Junji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  OKAYAMA UNIVERSITY
The analysis of the role and inhibition of heparanase in cancer metastasis and inflammation
- Principal Investigator
  
  NAOMOTO Yoshio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  OKAYAMA UNIVERSITY
Development of the supercooling preservation method for transplant liver graft and analysis of the mechanism of cold preservation injury
- Principal Investigator
  
  YAGI Takahito
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Drug Polymorphic triple nucleotide alterations in cell cycle transactivator E2F-4 and sensitivity to the anlicancer agents
- Principal Investigator
  
  MATSUBARA Nagahide
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University Hospital
NF-κ B mediated apoptosis induced by TNF/IFN-α
- Principal Investigator
  
  HAISA Minoru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University Hospital
Cell cycle transactivation factor E2F-4 is associate with the ganstrointestinal carcinogenesis and/or acquisition of chemoresistancePrincipal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Genetic diagnosis of gastrointestinal cancer using peripheral blood DNA or ascitis DNA
- Principal Investigator
  
  ISOZAKI Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Role of ornithine decarboxylase (ODC) as a oncogene in colorectal tumorigenesisPrincipal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Development of bioartificial liver support utilizing hepatocyte spheroids and its evaluation on pigs with liver failure.
- Principal Investigator
  
  KOIDE Norio
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Okayama University
Association of gastrointestinal cancer progression and the alteration of cancer related genes.
- Principal Investigator
  
  GOUCHI Akira
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
THE IMMUNOLOGICAL HYPORESPONSIVENESS AND DONOR CELL PERSISTENCE IN HOST LIVER AFER PORTAL VENOUS INNOCULATIONPrincipal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
体外循環システムによる抗腫瘍性リンパ球の誘導と癌治療の試み
- Principal Investigator
  
  ORITA Kunzo
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Activation of anti-tumor immunity during hepatic regeneration and the activation mechanism
- Principal Investigator
  
  ORITA Kunzo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Studies on the functions of the actirated lymphocytes after partial hepatectomyPrincipal Investigator
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Induction of nonspecific cytotoxic lymphocyte against cancer by interleukin 2, and the application for cancer therapy
- Principal Investigator
  
  ORITA Kunzo
- Project Period (FY)
  1983 – 1984
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Okayama University

All 2010 2009 2008 2007 2006 2005 2004 2003 2002

All Journal Article Presentation

[Journal Article] 便中メチル化DNA検出による消化器がんスクリーニング:消化器がんを非侵襲的にスクリーニングすることは可能か?2010
- Author(s)
  永坂岳司, 田中紀章, 孫冬生, 猶本良夫, 松原長秀, 八木孝仁, 藤原俊義
- Journal Title
  
  岡山医学会雑誌第122巻
  
  Pages: 107-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590572
[Journal Article] Targeting KRAS Mutation-bearing Lung Cancer In Vivo by Pulmonary Surfactant-Adenovirus-mediated Gene Transfer.2010
- Author(s)
  Fukazawa T, Maeda Y, Matsuoka J, Ono T, Mominoki K, Yamatsuji T, Shigemitsu K, Morita I, Murakami I, Tanaka H, Durbin ML, Naomoto Y.
- Journal Title
  
  Anticancer Research. 125
  
  Pages: 4925-4935
- Data Source
  KAKENHI-PROJECT-20390369
[Journal Article] Analysis of fecal DNA methylation to detect gastrointestinal neoplasia.2009
- Author(s)
  Nagasaka T, Tanaka N, Cullings HM, Sun DS, Sasamoto H, Uchida T, et al.
- Journal Title
  
  Journal of the National Cancer Institute 101(18)
  
  Pages: 1244-1258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590572
[Journal Article] Drug-regulatable cancer cell death induced by BID under control of the tissue-specific, lung cancer-targeted TTS promoter system.2009
- Author(s)
  Fukazawa T, Matsuoka J, Tanaka N, Tanaka H, Durbin ML Maeda Y, Naomoto Y.
- Journal Title
  
  Int J Cancer. 125
  
  Pages: 1975-1984
- Data Source
  KAKENHI-PROJECT-20390369
[Journal Article] Analysis of fecal DNA methylation to detect gastrointestinal neoplasia.2009
- Author(s)
  Nagasaka T, Tanaka N, Cullings HM, Sun DS, Sasamoto H, Uchida T, Koi M, Nishida N, Naomoto Y, Boland CR, Matsubara N, Goel A.
- Journal Title
  
  J Natl Cancer Inst. 101(18)
  
  Pages: 1244-1258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590572
[Journal Article] Mutations in both KRAS and BRAF contribute to the methylator phenotype in colon cancer. 134 : 1950-1960 (2008)2008
- Author(s)
  Nagasaka T. Koi M, Kloor M, Gebert J, Vilkin A, Nishida N, Shin S-K, Sasamoto H, Tanaka N, Matsubara N, Bol, C R, Goel A
- Journal Title
  
  Gastroenterology 134
  
  Pages: 1950-1960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Methylation pattern of the 06-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.2008
- Author(s)
  Nagasaka T, Goel A, Notohara K, Takahata T, Sasamoto H, Uchida T, Nishida N, Tanaka N, Boland CR, Matsubara N
- Journal Title
  
  Int J Cancer. 122(11)
  
  Pages: 2429-2436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590572
[Journal Article] Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis2008
- Author(s)
  Takeshi Nagasaka, Ajay Goel, Kenji Notohara, Takaomi Takahata, Hiromi Sasamoto, Takuyuki Uchida, Naoshi Nishida, Noriaki Tanaka, C. Richard Boland, Nagahide Matsubara
- Journal Title
  
  Int. J. Cancer 122
  
  Pages: 2429-2436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer.2008
- Author(s)
  Nagasaka T, Koi M, Kloor M, Gebert J, Vilkin A, Nishida N, Shin SK, Sasamoto H, Tanaka N, Matsubara N, Boland CR, Goel A.
- Journal Title
  
  Gastroenterology. 134(7)
  
  Pages: 1950-1960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590572
[Journal Article] Methylation pattern of the 06-methylguanlne一DNA methyltransferase gene in colon during progressive colorectal tumorigenesis. 122 : 2429-2436 (2008)2008
- Author(s)
  Nagasaka T, Goel Ajay, KenjiNotohara, Takaomi Takahata, Hiromi Sasamoto, Takuyuki Uchida, NaoshiNishida, Noriaki Tanaka, C. Richard Boland, Nagahide Matsubara
- Journal Title
  
  Int. J. Cancer 122
  
  Pages: 2429-2436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Malignant Pleural Mesothelioma-Targeted CREBBP/EP300 Inhibitory Protein 1 Promoter System for Gene Therapy and Virotherapy2008
- Author(s)
  Takuya Fukazawa, Junji Matsuoka, Yoshio Naomoto, Yutaka Maeda, Mary Durbin, Noriaki Tanaka
- Journal Title
  
  Cancer Research 68
  
  Pages: 7120-7129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659353
[Journal Article] Mutations in both KRAS and BRAF contribute to the methylator phenotype in colon cancer2008
- Author(s)
  Takeshi Nagasaka, Minoru Koi, Matthias Kloor, Johannes Gebert, Alex Vilkin, Naoshi Nishida, Sung Kwan Shin, Hiromi Sasamoto, Noriaki Tanaka, Nagahide Matsubara, C. Richard Boland, and Ajay Goel
- Journal Title
  
  Gastroenterology 134
  
  Pages: 1950-1960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Heparanase promotes angiogenesis through Cox-2 and HIFlalpha2007
- Author(s)
  Naomoto Y, Gunduz M, Takaoka M, Okawa T, Gunduz E, Nobuhisa T, Kobayashi M, Shirakawa Y, Yamatsuji T, Sonoda R, Matsuoka J, Tanaka N
- Journal Title
  
  Med Hypotheses 68
  
  Pages: 162-165
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] Oesophageal squamous cell cancer may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa.2007
- Author(s)
  Ishii, T., Murakami, J., Notohara, K., Cullings, H.M., Sasamoto, H., Kambara, T., Shirakawa, Y., Naomoto, Y., Ouchida, M., Shimizu, K., Tanaka, N., Jass, J.R., Matsubara.N
- Journal Title
  
  Gut 56
  
  Pages: 13-19
- Data Source
  KAKENHI-PROJECT-17390368
[Journal Article] Translocation of heparanase into nucleus results in cell differentiation2007
- Author(s)
  Nobuhisa, T., Naomoto, Y., Okawa, T., Takaoka, M., Gunduz, M., Motoki, T., Nagatsuka, H.,Tsujigiwa, H., Shirakawa, Y., Yamatsuji, T., Haisa, M., Matsuoka, J., Kurebayashi, J.,Nakajima, M., Taniguchi, S., Sagara, J., Dong, J., Tanaka, N
- Journal Title
  
  Cancer Sci 98 (4)
  
  Pages: 535-540
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] Heparanase promotes angiogenesis through Cox-2 and HIFlalpha2007
- Author(s)
  Naomoto, Y., Gunduz, M., Takaoka, M., Okawa, T., Gunduz, E., Nobuhisa, T., Kobayashi, M.,Shirakawa, Y., Yamatsuji, T., Sonoda, R., Matsuoka, J., Tanaka, N
- Journal Title
  
  Med Hypotheses 68 (1)
  
  Pages: 162-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oralcancer cell lines.2007
- Author(s)
  Murakami J, Lee YJ, Kokeguchi S, Tsujigiwa H, Asaumi J, Nagatsuka H, Fukui K, Kuroda M, Tanaka N, Matsubara N.
- Journal Title
  
  Onclo. Rep. 17(6):
  
  Pages: 1461-1467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Translocation of heparanase into nucleus results in cell differentiation2007
- Author(s)
  Nobuhisa T, Naomoto Y, Okawa T, Takaoka M, Gunduz M, Motoki T, Nagatsuka H, Tsujigiwa H, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Kurebayashi J, Nakajima M, Taniguchi S, Sagara J, Dong J, Tanaka N
- Journal Title
  
  Cancer Sci 98
  
  Pages: 535-540
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] Microsatellite instability and clinicopathological features in esophageal squamous cell cancer2007
- Author(s)
  Matsumoto, Y., Nagasaka, T., Kambara, T., Hoshizima, N., Murakami, J., Sasamoto, H., Hosokawa, M., Naomoto, Y., Isozaki, H., Shimizu, K., Tanaka, N., Matsubara, N.
- Journal Title
  
  Oncol. Rep. 18
  
  Pages: 1123-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] リンチ症候群のリクルートにおける病理組織・免疫染色・MSIテスト・somatic遺伝子検査の意義2007
- Author(s)
  松原長秀、永坂岳司、田中紀章
- Journal Title
  
  家族性腫瘍 7
  
  Pages: 11-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Oesophageal squamous cell cancer may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa2007
- Author(s)
  Ishii T, Murakami J, Notohara K, Cullings HM, Sasamoto H, Kambara T, Shirakawa Y, Naomoto Y, Ouchida M, Shimizu K, Tanaka N, Jass JR, Matsubara N
- Journal Title
  
  GUT 56
  
  Pages: 13-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591402
[Journal Article] Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa2007
- Author(s)
  Ishii T, Murakami J, Notohara K, Cullings HM, Sasamoto H, Kambara T, Shirakawa Y, Naomoto Y, Ouchida M, Shimizu K, Tanaka N, Jass JR, Matsubara N.
- Journal Title
  
  Gut 56
  
  Pages: 13-19
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] No duplicate KRAS mutation is identified on the same allele of gastric or colorectal cancer cells with multiple KRAS mutations.2007
- Author(s)
  Kimura, K., Nagasaka, T., Sasamoto, H., Notohara, K., Takeda, M., Komnami, K., Ishii, T., Tanaka, N., Matsubara, N.
- Journal Title
  
  J. Int. Med. Res. 35
  
  Pages: 450-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines2007
- Author(s)
  Murakami J, Lee YJ, Kokeguchi S, Tsujigiwa H, Asaumi J, Nagatsuka H, Fukui K, Kuroda M, Tanaka N, Matsubara N.
- Journal Title
  
  Oncol. Rep. 17(6)
  
  Pages: 1461-1467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Oesophageal squamous cell cancer may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa.2007
- Author(s)
  Ishii, T., Murakami, J., Notohara, K., Cullings, H.M., Sasamoto, H., Kambara, T., Shirakawa, Y., Naomoto, Y., Ouchida, M., Shimizu, K., Tanaka, N., Jass, J.R., Matsubara, N.
- Journal Title
  
  Gut 56
  
  Pages: 13-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390368
[Journal Article] Heparanase promotes angiogenesis through Cox-2 and HIF1alpha2007
- Author(s)
  Naomoto Y, Gunduz M, Takaoka M, Okawa T, Gunduz E, Nobuhisa T, Kobayashi M, Shirakawa Y, Yamatsuji T, Sonoda R, Matsuoka J, Tanaka N
- Journal Title
  
  Med Hypotheses 68
  
  Pages: 162-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] Pulmonary adenocarcinoma-targeted gene therapy by a cancer- and tissue-specific promoter system2007
- Author(s)
  Fukazawa T, Maeda Y, Durbin ML, Nakai T, Matsuoka J, Tanaka H, Naomoto Y, Tanaka N.
- Journal Title
  
  Molecular and Cancer Therapeutics 6巻・1号
  
  Pages: 244-252
- Data Source
  KAKENHI-PROJECT-18591548
[Journal Article] Oesophageal squamous cell cancer may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa2007
- Author(s)
  Ishii, T., Murakami, J., Notohara, K., Cullings, H. M., Sasamoto, H., Kambara, T., Shirakawa, Y., Naomoto, Y., Ouchida, M., Shimizu, K., Tanaka, N., Jass, J. R., Matsubara, N.
- Journal Title
  
  Gut 56 13-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa2007
- Author(s)
  Ishii T, Murakami J, Notohara K, Cullings HM, Sasamoto H, Kambara T, ShirakawaY, Naomoto Y, Ouchida M, Shimizu K, Tanaka N, Jass JR, Matsubara N.
- Journal Title
  
  Gut 56
  
  Pages: 13-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] Pulmonary adenocarcinoma-targeted gene therapy by a cancer-and tissue-specific promoter system2007
- Author(s)
  Fukazawa, T., Maeda, Y., Durbin, ML., Nakai, T., Matsuoka, J., Tanaka, H., Naomoto, Y., Tanaka, N
- Journal Title
  
  Mol Cancer Then 6
  
  Pages: 244-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591548
[Journal Article] Oesophageal squamous cell cancer may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa.2007
- Author(s)
  Ishii T., Murakami J., Notohara K., Cullings H.M., Sasamoto H., Kambara T., Shirakawa Y., Naomoto Y., Ouchida M., Shimizu K., Tanaka N., Jass J.R., Matsubara N.
- Journal Title
  
  Gut 56
  
  Pages: 13-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591402
[Journal Article] Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa2007
- Author(s)
  Ishii, T., Murakami, J., Notohara, K., Cullings, HM., Sasamoto, H., Kambara, T., Shirakawa, Y., Naomoto, Y., Ouchida, M., Shimizu, K., Tanaka, N., Jass, JR., Matsubara, N
- Journal Title
  
  Gut 56 (1)
  
  Pages: 13-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] No duplicate KRAS mutation is identified on the same allele of gastric or colorectal cancer cells with multiple KRAS mutations2007
- Author(s)
  Kimura, K., Nagasaka, T., Sasamoto, H., Notohara, K., Takeda, M., Komnami, K., Ishii, T., Tanaka, N., Matsubara, N.
- Journal Title
  
  J. Int. Med. Res 35
  
  Pages: 450-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis (2007)2007
- Author(s)
  Takeshi Nagasaka, Ajay Goel, Kenji Notohara, Takaomi Takahata, Hiromi Sasamoto, Takuyuki Uchida, Naoshi Nishida, Noriaki Tanaka, C. Richard Boland, Nagahide Matsubara
- Journal Title
  
  Int. J. Cancer (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] No duplicate KRAS mutation is identified on the same allele of gastric or colorectal cancer cells with multiple KRAS mutations.2007
- Author(s)
  Kimura, K., Nagasaka, T., Sasamoto, H., Notohara, K., Takeda, M., Komnami, K., Ishii, T., Tanaka, N., Matsubara, N.
- Journal Title
  
  J. Int. Med. Res.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390368
[Journal Article] Oesophageal squamous cell cancer may develop within a back ground of accumulating DNA methylation in normal and dys plastic mucosa.2007
- Author(s)
  Ishii, T., Murakami, J., Notohara, K., Cullings, H.M., Sasamoto, H., Kambara, T., Shirakawa, Y., Naomoto, Y., Ouchida, M., Shimizu, K., Tanaka, N., Jass, J. R., Matsubara, N.
- Journal Title
  
  Gut 56,
  
  Pages: 13-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] Microsatellite instability and clinicopathological features in esophageal squamous cell cancer. (2007)2007
- Author(s)
  Matsumoto, Y., Nagasaka, T., Kambara, T., Hoshizima N., Murakami, J., Sasamo to, H., Hosokawa, M., Naomoto, Y., Isozaki, H., Shimizu, K., Tanaka, N., Matsubara, N.
- Journal Title
  
  Oncol. Rep. 18,
  
  Pages: 1123-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390351
[Journal Article] The close relationship between heparanase and cyclooxygenase-2 expressions in signet-ring cell carcinoma of the stomach.2006
- Author(s)
  Ohtawa Y, Naomoto Y, Shirakawa Y, Takaoka M, Murata T, Sonoda R, Sakurama K, Yamatsuji T, Gunduz M, Tsujigiwa H, Nagatsuka H, Terada N, Itano S, Horiki S, Yanagihara K, Nakajima M, Tanaka N.
- Journal Title
  
  Hum Pathol. 37
  
  Pages: 1145-1152
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] Heterogeneous microsatellite instability observed within epithelium of ulcerative colitis.2006
- Author(s)
  Ozaki, K., Nagasaka, T., Notohara, K., Kambara, T., Takeda, M., Sasamoto, H., Jass, J.R., Tanaka, N., Matsubara, N.
- Journal Title
  
  Int. J. Cancer 119 (11)
  
  Pages: 2513-2519
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390368
[Journal Article] The close relationship between heparanase and cyclooxygenase-2 expressions in signet-ring cell carcinoma of the stomach2006
- Author(s)
  Ohtawa, Y., Naomoto, Y., Shirakawa, Y., Takaoka, M., Murata, T., Sonoda, R., Sakurama, K., Yamatsuji, T., Gunduz, M., Tsujigiwa, H., Nagatsuka, H., Terada, N., Itano, S., Horiki, S., Yanagihara, K., Nakajima, M., Tanaka, N
- Journal Title
  
  Hum Pathol 37 (9)
  
  Pages: 1145-1152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591464
[Journal Article] COX-2 induction by heparanase in the progression of breast cancer.2006
- Author(s)
  Imada T, Matsuoka J, Nobuhisa T, Okawa T, Murata T, Tabuchi Y, Shirakawa Y, Ohra N, Gunduz M, Nagatsuka H, Umeoka T, Yamamoto Y, Nakajima M, Tanaka N, Naomoto Y.
- Journal Title
  
  Int J Mol Med. Feb;17(2)
  
  Pages: 221-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Heterogeneous microsatellite instability observed within epithelium of ulcerative colitis in oral cancer.2006
- Author(s)
  Ozaki K, Nagasaka T, Notohara K, Kambara T, Takeda M, Sasamoto H, Jass JR, Tanaka N, Matsubara N
- Journal Title
  
  International Journal of Cancer 119
  
  Pages: 2513-2519
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591402
[Journal Article] Heterogeneous microsatellite instability observed within epithelium of ulcerative colitis.2006
- Author(s)
  Ozaki, K., Nagasaka, T., Notohara, K., Kambara, T., Takeda, M., Sasamoto, H., Jass, J.R., Tanaka, N., Matsubara,N.
- Journal Title
  
  Int.J.Cancer 119
  
  Pages: 2513-2519
- Data Source
  KAKENHI-PROJECT-17390368
[Journal Article] Heterogeneous microsatellite instability observed within epithelium of ulcerative colitis.2006
- Author(s)
  Ozaki K., Nagasaka T., Notohara K., Kambara T., Takeda M., Sasamoto H., Jass J.R., Tanaka N., Matsubara N.
- Journal Title
  
  Int. J. Cancer 119 (11)
  
  Pages: 2513-2519
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591402
[Journal Article] Effects of imatinib vary with the types of KIT-mutation in gastrointestinal stromal tumor cell lines.2005
- Author(s)
  Noma K, Naomoto Y, Gunduz M, Matsuoka J, Yamatsuji T, Shirakawa Y, Nobuhisa T, Okawa T, Takaoka M, Tomono Y, Hiroyuki 0, Gunduz E, Tanaka N.
- Journal Title
  
  Oncol Rep. Sep ; 14(3)
  
  Pages: 645-650
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Role of 06-methylguanine-DNA methyltransferase and effect of 06-benzylguanine on the anti-tumor activity of cis-Diaminedichloroplatinum(II) in oral cancer cell lines.2005
- Author(s)
  Yu Maki, Jun Murakami, Jun-ichi Asaumi, Hidetsugu Tsujigiwa, Hitoshi Nagatsuka, Susumu Kokeguchi, Kazuhiro Fukui, Noriko Kawai, Yoshinobu Yanagil, Masahiro Kuroda, Noriaki Tanaka, Nagahide Matsubara, Kanji Kishil
- Journal Title
  
  Oral Oncol. 41
  
  Pages: 984-993
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390368
[Journal Article] Methylatio profiles of genes utilizing newly developed CpG island methylation microarray on colorectal cancer patients.2005
- Author(s)
  Naoki Kimura, Takeshi Nagasaka, Jun Murakami, Hiromi Sasamoto, Masahiro Murakami, Noriaki Tanaka, Nagahide Matsubara
- Journal Title
  
  Nucleic Acids Res. 33 (5)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390368
[Journal Article] Methylatio profiles of genes utilizing newly developed CpG island methylation microarray on colorectal cancer patients.2005
- Author(s)
  Naoki Kimura, Takeshi Nagasaka, Jun Murakami, Hiromi Sasamoto, Masahiro Murakami, Noriaki Tanaka, Nagahide Matsubara
- Journal Title
  
  Nucleic Acids Res. 33(5)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] The role of heparanase in gastrointestinal cancer (Review).2005
- Author(s)
  Naomoto Y, Takaoka M, Okawa T, Nobuhisa T, Gunduz M, Tanaka N.
- Journal Title
  
  Oncol Rep. Jul ; 14(1) (Review)
  
  Pages: 3-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Heparanase expression correlates with malignant potential in human colon cncer.2005
- Author(s)
  Nobuhisa T, Naomoto Y, Ohkawa T, Takaoaka M, Ono R, Murata T, Gunduz M, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Tsujigiwa H, Nagatsuka H, Nakajima M, Tanaka N.
- Journal Title
  
  J Cancer Res Clin Oncol. Apr ; 131(4) Epub 2004 Dec 30
  
  Pages: 229-237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Heparanase is involved in angiogenesis in esophageal cancer through induction of cyclooxygenase-2.2005
- Author(s)
  Okawa T, Naomoto Y, Nobuhisa T, Takaoka M, Motoki T, Shirakawa Y, Yamatsuji T, Inoue H, Ouchida M, Gunduz M, Nakajima M, Tanaka N.
- Journal Title
  
  Clin Cancer Res. Nov 15 ; 11(22)
  
  Pages: 7995-8005
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Emergence of nuclear heparanase induces differentiation of human mammary cancer cells.2005
- Author(s)
  Nobuhisa T, Naomoto Y, Takaoka M, Tabuchi Y, Ookawa K, Kitamoto D, Gunduz E, Gunduz M, Nagatsuka H, Haisa M, Matsuoka J, Nakajima M, Tanaka N.
- Journal Title
  
  Biochem Biophys Res Commun. May 27 ; 331(l)
  
  Pages: 175-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Methylation assay by nucleotide incorporation (MANIC): a novel, nonisotopic, quantitative assay for regional CpG methylation density.2004
- Author(s)
  Takeshi Yamamoto, Takeshi Nagasaka, Kenji Notohara, Hiromi Sasamoto, Jun Murakami, Noriaki Tanaka, Nagahide Matsubara
- Journal Title
  
  Bio Tchniques 36
  
  Pages: 846-855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Localization o heparanase in esophageal cancer cells : respective roles in prognosis and differentiation.2004
- Author(s)
  OhkawaT, Naomoto Y, Takaoka M, Nobuhisa T, Noma K, Motoki T, Murata T, Uetsuka H, Kobayashi M, Shirakawa Y, Yamatsuji T, Matsubara N, Matsuoka J, Haisa M, Gunduz M, Tsujigiwa H, Nagatsuka H, Hosokawa M, Nakajima M, Tanaka N.
- Journal Title
  
  Lab Invest. Oct ; 84(10)
  
  Pages: 1289-1304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes show different patterns of DNA methylation.2004
- Author(s)
  Takeshi Nagasaka, Hiromi Sasamoto, Kenji Notohara, Harry M.Cullings, Masanori Takeda, Keigo Kimura, Takeshi Kambara, Donald G.MacPhee, Joanne Young, Barbara A.Leggett, Jeremy R.Jass, Noriaki Tanaka, Nagahide Matsubara
- Journal Title
  
  J. Clip. Oncol. 22(22)
  
  Pages: 4584-4594
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Allelic loss of a common microsatellite marker MYcL1: a useful prognostic factor of poor outcomes in colorectal cancer.2004
- Author(s)
  Kambara, T., Sharp, GB., Nagasaka, T., Takeda, M., Sasamoto, H., Nakagawa, H., Isozaki, H., MacPhee, D.G., Jass, J.R., Tanaka, N., Matsubara, N.
- Journal Title
  
  Clinical Cancer Res. 10
  
  Pages: 1758-1763
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Role of Inherited Defects of MYH in the Development of Sporadic Colorectal Cancer.2004
- Author(s)
  Takeshi Kambara, Vicki L.J.Whitehall, Kevin J.Spring, Melissa A.Barker, Sven Arnold, Coral V.A.Wynter, Nagahide Matsubara, Noriaki Tanaka, Joanne P.Young, Barbara A.Leggett, Jeremy R.Jass
- Journal Title
  
  Gene Chromosome Canc. 40
  
  Pages: 1-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.2004
- Author(s)
  Takeshi Kambara, Lisa A.Simms, Vicki L.J.Whitehall, Kevin J.Spring, Coral V.A.Wynter, Michael D.Walsh, Melissa A.Barker, Sven Arnold, Andrina McGivern, Nagahide Matsubara, Noriaki Tanaka, Tetsuro Higuclu, Joanne Young, Jeremy R.Jass, Barbara A.Leggett
- Journal Title
  
  Gut 53
  
  Pages: 1137-1144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Allele-specific methylation analysis on upstream promoter region of H19 by methylation-specific PCR with confronting two-pair primers.2004
- Author(s)
  Hiromi Sasamoto, Takeshi Nagasaka, Kenji Notohara, Kazuo Ozaki, Hiroshi Isozaki, Noriaki Tanaka, Nagahide Matsubara
- Journal Title
  
  Int. J. Oncol. 25
  
  Pages: 1273-1278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Effects of demethylating agent 5-aza-2'-deoxycytidine and histone deacetylase inhibitor FR901228 on maspin gene expression in oral cancer cell lines.2004
- Author(s)
  Murakami, J., Asaumi, J., Maki, Y., Tsujigiwa, H., Kuroda M., Nagai, N., Yanagi, Y., Inoue, T., Kawasaki, S., Tanaka, N., Matsubara.N., Kishi K.
- Journal Title
  
  Oral Oncol. 40
  
  Pages: 597-603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Influence of CpG island methylation status in 06-methylguanine-DNA methyltransferase expression of oral cancer cell lines.2004
- Author(s)
  Murakami, J., Asaumi, J., Maki, Y., Tsujigiwa, H., Nagatsuka, H., Kokeguchi, S., Inoue, T., Kawasaki, S., Tanaka, N., MacPhee, D., Matsubara, N., Kishi, K.
- Journal Title
  
  Oncol. Rep. 12
  
  Pages: 339-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Effects of histone deacetylase inhibitor FR901228 on expression level of telomerase reverse transcriptase in oral cancer.2004
- Author(s)
  Jun Murakami, Junichi Asaumi, Noriko Kawai, Hidetsugu Tsujigiwa, Yoshinobu Yanagi, Hitoshi Nagatsuka, Tetsuyoshi Inoue, Susumu Kokeguchi, Shoji Kawasaki, Masahiro Kuroda, Noriaki Tanaka, Nagahide Matsubara, Kanji Kishi
- Journal Title
  
  Cancer Chemoth. Pharm.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Heparanase expression correlates with invasion and poor prognosis in gastric cancers.2003
- Author(s)
  Takaoaka M, Naomoto Y, Ohkawa T, Uetsuka H, Shirakawa Y, Uno F, Fujiwara T, Gunduz M, Nagatsuka H, Nakajima M, Tanaka N, Haisa M.
- Journal Title
  
  Lab Invest. May ; 83(5)
  
  Pages: 613-622
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591319
[Journal Article] Hypermethylation of 06-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer cases.2003
- Author(s)
  Nagasaka, T., Sharp, GB., Notohara, K., Kambara, T., Sasamoto, H., Isozaki, H., MacPhee, D.G., Jass, J.R., Tanaka, N., Matsubara, N.
- Journal Title
  
  Clinical Cancer Res. 9
  
  Pages: 5306-5312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Journal Article] Allelic imbalance and microsatellite instability in plasma DNA released from polyclonal pancreatic adenocarcinoma.2002
- Author(s)
  Moriyama, H., Matsubara, N., Kambara, T., Mori, M., Matsuoka, J., Yoshino, T., Takakura, N., Shimizu, K., Tanaka, N.
- Journal Title
  
  Int. J. Oncol. 21
  
  Pages: 949-956
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571198
[Presentation] 便中DNAによる大腸癌発見法2008
- Author(s)
  松原長秀、永坂岳司、田中紀章
- Organizer
  第14回日本家族性腫瘍学会学術集会
- Place of Presentation
  国立がんセンター東京(シンポジウム)
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] Malignant Pleural Mesothelioma-Targeted CREBBP/EP300 Inhibitory Protein 1 Promoter System for Gene Therapy and Virotherapy2008
- Author(s)
  Takuya Fukazawa, Junji Matsuoka, Yoshio Naomoto, Yutaka Maeda, Nakai Torn, Inoue Fumiyuki, Takahashi Masahiko, Mary Durbin, Noriaki Tanaka
- Organizer
  日本癌学会第67回学術総会(English Workshop)
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19659353
[Presentation] 大腸癌の前癌病変を含めた早期診断法の確立とtranslational researchへの問題点2008
- Author(s)
  松原長秀、永坂岳司、内田卓之、笹本博美、戸田桂介、谷口信将、岡哲弘、田中紀章
- Organizer
  第63回日本消化器外科学会総会
- Place of Presentation
  札幌(ワークショップ)
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] 大腸癌のepigenetic変異をコントロールするパスウェイとこれに基づく亜分類の診断・治療への応用2008
- Author(s)
  松原長秀, 永坂岳司, 近藤喜太, 田中紀章
- Organizer
  第63回日本大腸肛門病学会学術集会
- Place of Presentation
  ホテル日航東京
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] 大腸癌のepigenetic変異をコントロールするパスウェイとこれに基づく亜分類の診断・治療への応用2008
- Author(s)
  松原長秀、永坂岳司、近藤喜太、田中紀章
- Organizer
  第63回日本大腸肛門病学会学術集会
- Place of Presentation
  ホテル日航東京(パネルディスカッション)
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] 大腸癌鋸歯状病変よりの発癌機構と大腸癌に於ける位置づけ2008
- Author(s)
  松原長秀,長尾厚樹,神原健,田中紀章
- Organizer
  第19回日本消化器癌発生学会総会
- Place of Presentation
  別府亀の井ホテル(ミニシンポジウム)
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] Does laparoscopic surgery for colorectal cancer really contribute a lot to the post-operative patient's life2008
- Author(s)
  Nagahide Matsubara, Yoshitaka Kondo, Naoya Kobayashi, Noriaki Tanaka
- Organizer
  11^<th> World Congress of Endoscopic Surgery
- Place of Presentation
  Yokohama, Japan(Workshop)
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] リンチ症候群の大腸癌におけるepigeneticの関与2007
- Author(s)
  松原長秀、永坂岳司、神原健、田中紀章
- Organizer
  第45回日本癌治療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] Multimodal treatment for rectal cancer. Symposium : Current topics of the surgical treatment for rectal cancer2007
- Author(s)
  Nagahide Matsubara, Noriaki Tanaka
- Organizer
  The International College of Surgeons. 17^<th> Joint Congress of Asia & Pacific Federations & 53^<rd> Annual Congress of the Japanese Section
- Place of Presentation
  Westin Miyako Hotel Kyoto, Kyoto, Japan.
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] HNPCC screening上の課題 : シンポジウム[家族性腫瘍-基礎と臨床]2007
- Author(s)
  松原長秀, 永坂岳司, 能登原憲司, 笹本博美, 田中紀章
- Organizer
  第13回日本家族性腫瘍学会
- Place of Presentation
  高知
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] 大腸鋸歯状ポリープよりの発癌機構とその病変の大腸癌における位置づけ2007
- Author(s)
  松原長秀、長尾厚樹、神原健、田中紀章
- Organizer
  第88回日本消化器病学会中国支部例会
- Place of Presentation
  岡山コンベンションセンター岡山
- Data Source
  KAKENHI-PROJECT-19390351
[Presentation] Malignant pleural mesothelioma-targeted gene therapy2007
- Author(s)
  Takuya Fukazawa, Junji Matsuoka, Yoshio Naomoto, Yuataka Maeda, Mary L. Durbin, Noriaki Tanaka.
- Organizer
  2007 AACR Annual Meeting
- Place of Presentation
  Los Angeles, CA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591464
[Presentation] HUMAN NON-SMALL CELL LUNG CANCER TARGETED PROMOTER SYSTEM FOR GENE THERAPY2006
- Author(s)
  Fukazawa, T., Matsuoka, J., Naomoto, Y., Nakai, T., Maeda, Y., Frances, M., Sladek, Laurie, B., Owen-Schaub, Jeffrey, Whitsett, Tanaka, N
- Organizer
  65th Annual Meeting of Japanese Association for Cancer Research
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591548

1. MATSUBARA Nagahide (70314672)

# of Collaborated Projects: 8 results

# of Collaborated Products: 51 results
2. SHIMIZU Kenji (10037286)

# of Collaborated Projects: 8 results

# of Collaborated Products: 7 results
3. MATSUOKA Jyunji (30332795)

# of Collaborated Projects: 6 results

# of Collaborated Products: 18 results
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# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
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# of Collaborated Projects: 4 results

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9. MOCHITATE Katsumi (20132863)

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10. FUKAZAWA Takuya (20379845)

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11. TABATA Yashuiko (50211371)

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12. YOKOI Yokoishi (70135226)

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13. TANAKA Hirotosh (00171794)

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14. KONDO Eisaku (30252951)

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15. NAGASAKA Takeshi (30452569)

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16. SAKAGAMI Kennichi (40124789)

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17. KOIDE Norio (20142333)

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18. ISOZAKI Hiroshi (50151436)

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19. HAISA Minoru (70322229)

# of Collaborated Projects: 2 results

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20. KAMBARA Takeshi (60379724)

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22. 大山和美 (00253021)

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23. NAKAJI Syuhei

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24. KATO Jun (90379743)

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25. KATAYAMA Hiroshi (90161067)

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26. ONO Toshiro (50185641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. MOMINOKI Katsumi (70304615)

# of Collaborated Projects: 1 results

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28. TSUTYA Tomoshi (30437884)

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29. KONDOU Yoshitaka (50534765)

# of Collaborated Projects: 1 results

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30. SASAMOTO Hiromi (10452567)

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31. HAMAZAKI Keisuke (90172965)

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32. GOUCHI Akira (10186877)

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33. YAGI Takahito (00304353)

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34. MIYAZAKI Masahiro (90116509)

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35. KOBAYASHI Eiji (00245044)

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36. KURABAYASHI Yuzuru (90033373)

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37. KOHARA Michinori (10250218)

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38. HAYATSU Hikoya (10012593)

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39. MIMURA Hisashi (80116508)

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40. 米澤一仁 (70283900)

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41. 吉野健一 (90280792)

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50. 繁光薫

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51. 児玉亮

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TANAKA Noriaki 田中 紀章

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Hepatic differentiation of human embryonic stem cells and its application to the development of a bioartificial liver systemPrincipal Investigator

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第三世代制限増殖ウイルスベクターを用いた瀰漫性胸膜中皮腫に対する新規治療法の開発Principal Investigator

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Elucidation, of the interacting mechanism between epigenetic and genetic alterations in gastrointestinal cancers and of the possible application to the clinicPrincipal Investigator

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Development of Regenerative Medicine Using Reversibly Proliferating Human Bone Marrow Mesenchymal Stem CellsPrincipal Investigator

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Bioartificial liver development using reversibly immortalized human liver cell lines.Principal Investigator

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TANAKA Noriaki 田中紀章