Kojima Takahiro 小島崇宏

… Alternative Names

KOJIMA Takahiro 小島崇宏

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Researcher Number	40626892
Affiliation (Current)	2025: 愛知県がんセンター(研究所), 腫瘍制御学分野, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 愛知県がんセンター(研究所), 腫瘍制御学分野, 研究員 2019 – 2021: 筑波大学, 医学医療系, 准教授 2012 – 2018: 筑波大学, 医学医療系, 講師
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Urology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 52040:Radiological sciences-related / Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator 肉腫様腎細胞癌 / 患者由来細胞 / 前立腺がん / RNA / バイオマーカー / 免疫治療 / トランスクリプトーム解析 / 一塩基多型 / 変異 / 分子基盤 … More / 体細胞変異 / 膀胱癌 / cfDNA / SNP / ctDNA / 環境要因 / 遺伝要因 / 遺伝子変異 / 尿路上皮癌 / 肉腫様変化 / 低分子量Gタンパク / 腎細胞癌 / マイクロアレイ / DNAコピー数異常 / 遺伝子異常 … More Except Principal Investigator 腫瘍免疫 / 尿路上皮癌 / 膀胱癌 / BCG / 癌免疫 / TDM / ミコール酸 / アブスコパル効果 / 免疫チェックポイント阻害剤 / 転移性腎癌 / 定位放射線治療 / 放射線治療 / リピドミクス / 細胞外微小環境 / FGFR3 / 脂肪酸 / 骨盤神経損傷モデル / アデノシン / アンメットメディスン / ラットモデル / コリンエステラーゼ阻害剤 / アデノシン受容体 / 骨盤神経損傷 / アデノシン受容体シグナル / アニマルモデル / アデノシンレセプター / 低活動膀胱 / 泌尿器癌 / リキッドバイオプシー / CTC / 腎癌 / bladder instillation / bladder tumor / anti-tumor peptide / 毒性試験 / 膀胱注入 / 膀胱移植モデル / p19 / p14 / p16 / 機能性ペプチド / 膀胱腫瘍 / mycobacterium bovis BCG / 抗酸菌表層糖脂質 / trehalose-6 6’-dimycolate / 細胞壁成分 / 感染免疫 / 抗酸菌 / コードファクター / トレハロース 6,6′-ジミコラート / リンパ球 / 脂質 / 癌免疫療法 / リポソーム / ASIC/ENaC / 閉経モデルマウス / ENac / AISC / 排尿障害モデル / 筋層浸潤膀胱癌 / ENaC / ASIC / 膀胱発癌 / 膀胱機能障害 / BBN発癌モデル / 閉経モデル / 感覚受容体 / 神経因性膀胱 / 膀胱放射線照射モデル / 幹細胞移植 / 下部尿路放射線照射モデル / 膀胱機能障害病態モデル / 骨格筋間質由来幹細胞 / 微小環境 / 炎症細胞 / TET2 / メラノーマ / マウスモデル / クローン造血 / がん免疫応答 / がん微小環境 / 免疫環境 / 遺伝子変異 / PD-L1 / 発癌 / 腫瘍微小環境 / ノックアウトマウス / モルモットモデル / Mycobacterium bovie BCG / Trem2 / Mincle / CD1b / Mycobacterium bovis BCG / 脂質免疫 / モルモット膀胱癌 / Rb / 悪性転化 / 奇形腫 / ガンキリン / 精巣腫瘍 / testicular cancer / gankyrin Less

A randomized controlled trial to verify the synergistic effect of nivolumab and radiotherapy in metastatic renal cell carcinoma
- Principal Investigator
  
  大西洋
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Yamanashi
前立腺がん患者由来細胞を用いた個別化前臨床モデルの作成と分子機構の解明Principal Investigator
- Principal Investigator
  
  小島崇宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Aichi Cancer Center Research Institute
泌尿器癌における全血RNAを用いた免疫細胞の多様性の理解と治療効果予測への応用Principal Investigator
- Principal Investigator
  
  小島崇宏
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Aichi Cancer Center Research Institute
To elucidate the pathophysiological mechanism and explore the therapeutic target of underactive bladder / detrusor underactivity with focusing on the adenosine signaling pathway
- Principal Investigator
  
  高岡栄一郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Jichi Medical University
  International University of Health and Welfare
Elucidation of the significance of the quality of fatty acids in the bladder cancer
- Principal Investigator
  
  Matsuzaka Takashi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  University of Tsukuba
Efficacy and toxicity of bladder instillation of anti-tumor peptide for inhibition of bladder tumor in mice
- Principal Investigator
  
  Shimazui Toru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
クラスターCTCに注目した泌尿器癌の分子基盤に基づいたバイオマーカーの開発
- Principal Investigator
  
  松岡妙子
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
Tumor-supporting mechanisms by inflammatory cells with somatic mutations
- Principal Investigator
  
  Sakata-Yanagimoto Mamiko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  University of Tsukuba
Development of novel molecular characterization for urothelial cancer based on genetic and environmental factorsPrincipal Investigator
- Principal Investigator
  
  Kojima Takahiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
The establishment of a novel treatment in neurogenic bladder by the transplantation of the stem cells derived from the skeletal muscle stroma
- Principal Investigator
  
  Hoshi Akio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
To elucidate the mechanisms of carcinogenesis and invasion of bladder cancer via ASIC / ENaC signal pathway
- Principal Investigator
  
  NISHIYAMA HIROYUKI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  University of Tsukuba
Development of antitumor immunological agent using mycobacterial surface glycolipids as lead compounds.
- Principal Investigator
  
  NISHIYAMA Hiroyuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
Elucidation of BCG resistance mechanism by comprehensive analysis of immune environment and gene mutation in bladder cancer
- Principal Investigator
  
  Joraku Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Tsukuba
Clarification of the tumor microenvironment in the development of urothelial carcinoma using animal model
- Principal Investigator
  
  Nishiyama Hiroyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  University of Tsukuba
The roles of RAC2-VAV1 signaling in oncogenesis and sarcomatoid differentiation of renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  Kojima Takahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Tsukuba
Expression of the oncoprotein gankyrin and phosphorylated retinoblastoma protein in human testis and testicular germ cell tumor
- Principal Investigator
  
  SUETOMI TAKAHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Tsukuba
Identification of characteristic gene expression and molecular target in sarcomatoid renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  KOJIMA Takahiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  University of Tsukuba

All 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012

All Journal Article Presentation

[Journal Article] Whole-Blood Gene Expression Profiles Correlate with Response to Immune Checkpoint Inhibitors in Patients with Metastatic Renal Cell Carcinoma.2022
- Author(s)
  Nagumo Y, Kandori S, Kojima T, Hamada K, Nitta S, Chihara I, Shiga M, Negoro H, Mathis BJ, Nishiyama H.
- Journal Title
  
  Cancers (Basel)
  
  Volume: 14 Issue: 24 Pages: 6207-6219
- DOI
  10.3390/cancers14246207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09365
[Journal Article] The liposome of trehalose dimycolate extracted from M. bovis BCG induces antitumor immunity via the activation of dendritic cells and CD8+ T cells2021
- Author(s)
  Shiga Masanobu、Miyazaki Jun、Tanuma Kozaburo、Nagumo Yoshiyuki、Yoshino Takayuki、Kandori Shuya、Negoro Hiromitsu、Kojima Takahiro、Tanaka Ryota、Okiyama Naoko、Fujisawa Yasuhiro、Watanabe Miyuki、Yamasaki Sho、Kiyohara Hideyasu、Watanabe Makoto、Sato Taka-aki、Tahara Hideaki、Nishiyama Hiroyuki、Yano Ikuya
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: - Issue: 9 Pages: 2529-2543
- DOI
  10.1007/s00262-021-02870-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-18H02934
[Journal Article] Bladder preservation therapy in combination with atezolizumab and radiation therapy for invasive bladder cancer (BPT-ART) ? A study protocol for an open-label, phase II, multicenter study2021
- Author(s)
  Sekino Yuta、Ishikawa Hitoshi、Kimura Tomokazu、Kojima Takahiro、Maruo Kazushi、Azuma Haruhito、Yoshida Ken、Kageyama Yukio、Ushijima Hiroki、Tsuzuki Toyonori、Sakurai Hideyuki、Nishiyama Hiroyuki
- Journal Title
  
  Contemporary Clinical Trials Communications
  
  Volume: 21 Pages: 100724-100724
- DOI
  10.1016/j.conctc.2021.100724
- NAID
  120007186936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09158
[Journal Article] ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma2021
- Author(s)
  Tanaka Ken、Kandori Shuya、Sakka Shotaro、Nitta Satoshi、Tanuma Kozaburo、Shiga Masanobu、Nagumo Yoshiyuki、Negoro Hiromitsu、Kojima Takahiro、Mathis Bryan、Shimazui Toru、Watanabe Makoto、Sato Taka-Aki、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi、Nishiyama Hiroyuki
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 2 Pages: 23-23
- DOI
  10.3892/or.2021.8234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] Prognostic significance of non-urothelial carcinoma of bladder: analysis of nationwide hospital-based cancer registry data in Japan2020
- Author(s)
  Nagumo Yoshiyuki、Kawai Koji、Kojima Takahiro、Shiga Masanobu、Kojo Kosuke、Tanaka Ken、Kandori Shuya、Kimura Tomokazu、Kawahara Takashi、Okuyama Ayako、Higashi Takahiro、Nishiyama Hiroyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 9 Pages: 1068-1075
- DOI
  10.1093/jjco/hyaa072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-19K09705, KAKENHI-PROJECT-18K09158
[Journal Article] Bladder preservation therapy for muscle invasive bladder cancer: the past, present and future2020
- Author(s)
  Kimura Tomokazu、Ishikawa Hitoshi、Kojima Takahiro、Kandori Shuya、Kawahara Takashi、Sekino Yuta、Sakurai Hideyuki、Nishiyama Hiroyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 10 Pages: 1097-1107
- DOI
  10.1093/jjco/hyaa155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-18K09158
[Journal Article] Effect of neoadjuvant chemotherapy on health-related quality of life in patients with muscle-invasive bladder cancer: results from JCOG0209, a randomized phase III study2020
- Author(s)
  Kitamura Hiroshi、Hinotsu Shiro、Tsukamoto Taiji、Shibata Taro、Mizusawa Junki、Kobayashi Takashi、Miyake Makito、Nishiyama Naotaka、Kojima Takahiro、Nishiyama Hiroyuki、Urologic Oncology Study Group of the Japan Clinical Oncology Group
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 12 Pages: 1464-1469
- DOI
  10.1093/jjco/hyaa123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09158
[Journal Article] Recent malignant testicular tumor trend in Japan, a country with an aging population: a large-scale study of 2012?2015 hospital-based cancer registry data2020
- Author(s)
  Kojo Kosuke、Kawai Koji、Kawahara Takashi、Kimura Tomokazu、Kandori Shuya、Nagumo Yoshiyuki、Nitta Satoshi、Kojima Takahiro、Okuyama Ayako、Higashi Takahiro、Nishiyama Hiroyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 10 Pages: 1201-1208
- DOI
  10.1093/jjco/hyaa110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-17H03589, KAKENHI-PROJECT-18K09158
[Journal Article] Prognostic impact of non‐urothelial carcinoma of the upper urinary tract: Analysis of hospital‐based cancer registry data in Japan2020
- Author(s)
  Nagumo Yoshiyuki、Kawai Koji、Kojima Takahiro、Shiga Masanobu、Kojo Kosuke、Tanaka Ken、Kandori Shuya、Kimura Tomokazu、Kawahara Takashi、Okuyama Ayako、Higashi Takahiro、Nishiyama Hiroyuki
- Journal Title
  
  International Journal of Urology
  
  Volume: 28 Issue: 1 Pages: 54-60
- DOI
  10.1111/iju.14393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-18K09158
[Journal Article] Significance of the timing of ureteral ligation on prognosis during radical nephroureterectomy for upper urinary tract urothelial cancer2020
- Author(s)
  Inokuchi Junichi、Kuroiwa Kentaro、Nishiyama Hiroyuki、Kojima Takahiro、et al.
- Journal Title
  
  International Journal of Urology
  
  Volume: 28 Issue: 2 Pages: 208-214
- DOI
  10.1111/iju.14435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09158
[Journal Article] Impact of cytoreductive nephrectomy in patients with primary metastatic renal cell carcinoma receiving systemic tyrosine kinase inhibitor therapy: A multicenter retrospective study2020
- Author(s)
  Hatakeyama Shingo、Naito Sei、Numakura Kazuyuki、Kato Renpei、Koguchi Tomoyuki、Kojima Takahiro、Kawasaki Yoshihide、Kandori Shuya、Kawamura Sadafumi、Tsushima Eiki、Nishiyama Hiroyuki、Ito Akihiro、Kojima Yoshiyuki、Habuchi Tomonori、Obara Wataru、Tsuchiya Norihiko、Ohyama Chikara
- Journal Title
  
  International Journal of Urology
  
  Volume: 28 Issue: 4 Pages: 369-375
- DOI
  10.1111/iju.14466
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-20K09517, KAKENHI-PROJECT-16H02679, KAKENHI-PROJECT-18K09158
[Journal Article] Risk stratification for the prognosis of patients with chemoresistant urothelial cancer treated with pembrolizumab2020
- Author(s)
  Kobayashi T,Ito K,Kojima T,Kato M,Kanda S,Hatakeyama S,Matsui Y,Matsushita Y,Naito S,Shiga M,Miyake M,Muro Y,Nakanishi S,Kato Y,Shibuya T,Hayashi T,Yasumoto H,Yoshida T,Uemura M,Taoka R,Kamiyama M,Ogawa O,Kitamura H,Nishiyama H,the Japan Urological Oncology Group
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 2 Pages: 760-773
- DOI
  10.1111/cas.14762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09729, KAKENHI-PROJECT-18K09158
[Journal Article] TP53 codon 72 polymorphism is associated with FGFR3 and RAS mutation in non-muscle-invasive bladder cancer2019
- Author(s)
  Kawahara Takashi、Kojima Takahiro、Kandori Shuya、Kurobe Masahiro、Yoshino Takayuki、Kimura Tomokazu、Nagumo Yoshiyuki、Ishituka Ryutaro、Mitsuzuka Koji、Narita Shintaro、Kobayashi Takashi、Matsui Yoshiyuki、Ogawa Osamu、Sugimoto Mikio、Miyazaki Jun、Nishiyama Hiroyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 8 Pages: 220173-220173
- DOI
  10.1371/journal.pone.0220173
- NAID
  120007133062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09158, KAKENHI-PROJECT-19K09664
[Journal Article] Cationized liposomal keto-mycolic acids isolated from Mycobacterium bovis bacillus Calmette-Gu?rin induce antitumor immunity in a syngeneic murine bladder cancer model2019
- Author(s)
  Yoshino Takayuki、Miyazaki Jun、Kojima Takahiro、Kandori Shuya、Shiga Masanobu、Kawahara Takashi、Kimura Tomokazu、Naka Takashi、Kiyohara Hideyasu、Watanabe Miyuki、Yamasaki Sho、Akaza Hideyuki、Yano Ikuya、Nishiyama Hiroyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 1 Pages: 1-19
- DOI
  10.1371/journal.pone.0209196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-18H02934, KAKENHI-PROJECT-17K16774, KAKENHI-PROJECT-17K11124, KAKENHI-PROJECT-17H04087
[Journal Article] High prevalence of hypogonadism determined by serum free testosterone level in Japanese testicular cancer survivors2018
- Author(s)
  Kurobe Masahiro、Kawai Koji、Suetomi Takahiro、Iwamoto Teruaki、Waku Natsui、Kawahara Takashi、Kojima Takahiro、Joraku Akira、Miyazaki Jun、Nishiyama Hiroyuki
- Journal Title
  
  International Journal of Urology
  
  Volume: in print Issue: 5 Pages: 457-462
- DOI
  10.1111/iju.13537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293349
[Journal Article] TRPV4-dependent induction of a novel mammalian cold-inducible protein SRSF5 as well as CIRP and RBM32017
- Author(s)
  Fujita Takanori、Higashitsuji Hiroaki、Higashitsuji Hisako、Liu Yu、Itoh Katsuhiko、Sakurai Toshiharu、Kojima Takahiro、Kandori Shuya、Nishiyama Hiroyuki、Fukumoto Motoi、Fukumoto Manabu、Shibasaki Koji、Fujita Jun
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 2295-2295
- DOI
  10.1038/s41598-017-02473-x
- NAID
  120007129048
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16774, KAKENHI-PROJECT-26293349, KAKENHI-PUBLICLY-16H01387, KAKENHI-PROJECT-15H03000, KAKENHI-PROJECT-16K15571
[Journal Article] Possible risk of overestimation of renal function using cystatin C-based eGFR in testicular cancer survivors treated with cisplatin-based chemotherapy2017
- Author(s)
  Ichioka Daishi、Kawai Koji、Tanaka Ken、Ishitsuka Ryutaro、Yoshino Takayuki、Kimura Tomokazu、Kandori Shuya、Kawahara Takashi、Kojima Takahiro、Usui Joichi、Yamagata Kunihiro、Miyazaki Jun、Nishiyama Hiroyuki
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: in print Issue: 3 Pages: 727-734
- DOI
  10.1007/s10157-017-1474-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16774, KAKENHI-PROJECT-26293349
[Journal Article] Development of RNA-FISH Assay for Detection of Oncogenic FGFR3-TACC3 Fusion Genes in FFPE Samples.2016
- Author(s)
  7)Kurobe M, Kojima T, Nishimura K, Kandori S, Kawahara T, Yoshino T, Ueno S, Iizumi Y, Mitsuzuka K, Arai Y, Tsuruta H, Habuchi T, Kobayashi T, Matsui Y, Ogawa O, Sugimoto M, Kakehi Y, Nagumo Y, Tsutsumi M, Oikawa T, Kikuchi K, Nishiyama H.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 12 Pages: e0165109-e0165109
- DOI
  10.1371/journal.pone.0165109
- NAID
  120005980906
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02679, KAKENHI-PROJECT-26293349
[Journal Article] Expression of the oncoprotein gankyrin and phosphorylated retinoblastoma protein in human testis and testicular germ cell tumor.2014
- Author(s)
  Satoshi Ando, Taeko Matsuoka, Koji Kawai, Shintaro Sugita, Akira Joraku, Takahiro Kojima, Takahiro Suetomi, Jun Miyazaki, Jun Fujita and Hiroyuki Nishiyama
- Journal Title
  
  International Journal of Urology
  
  Volume: 21 Issue: 10 Pages: 992-998
- DOI
  10.1111/iju.12484
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592376, KAKENHI-PROJECT-24592446
[Journal Article] Case of metastatic malignant melanoma of the urinary bladder2013
- Author(s)
  Ikeda A, Miyagawa T, Kurobe M, Uchida M, Kojima T, Tsutsumi M, Ito S, Sugita S, Nishiyama H
- Journal Title
  
  Hinyokika Kiyo
  
  Volume: 59(9) Pages: 579-82
- NAID
  120005333767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791634
[Journal Article] Systemic transduction of p16INK4A antitumor peptide inhibits the growth of MBT-2 mouse bladder tumor cell line grafts2013
- Author(s)
  Shimazui T, Yoshikawa K, Miyazaki J, Kojima T, Inai H, Ando S, Uemura H, Uchida K, Nishiyama H
- Journal Title
  
  Int. J. Oncol
  
  Volume: Vo l .42 Issue: 2 Pages: 543-54
- DOI
  10.3892/ijo.2012.1752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590282, KAKENHI-PROJECT-23592330, KAKENHI-PROJECT-24592375, KAKENHI-PROJECT-24592415, KAKENHI-PROJECT-24791634
[Journal Article] Oncological outcomes of metastatic testicular cancers under centralized management through regional medical network2013
- Author(s)
  Inai H, Kawai K, Kojima T, Joraku A, Shimazui T, Yamauchi A, Miyagawa T, Endo T, Fukuhara Y, Miyazaki J, Uchida K, Nishiyama H
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 43(12) Issue: 12 Pages: 1249-54
- DOI
  10.1093/jjco/hyt152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791634
[Journal Article] Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice.2012
- Author(s)
  Oishi H et al.
- Journal Title
  
  J. Biochem
  
  Volume: 152 Issue: 6 Pages: 549-555
- DOI
  10.1093/jb/mvs100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390115, KAKENHI-PROJECT-22590282, KAKENHI-PROJECT-23590325, KAKENHI-PROJECT-24791634
[Journal Article] Management of ureteral obstruction in advanced testicular tumor with lymph node metastasis2012
- Author(s)
  Ikeda A, Kawai K, Miyazaki J, Nishiyama H.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 42(8) Issue: 8 Pages: 52-748
- DOI
  10.1093/jjco/hys094
- NAID
  120007137102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592330, KAKENHI-PROJECT-24791634
[Journal Article] Genome-wide identification of endothelial cell-enriched genes in the mouse embryo2012
- Author(s)
  Takase H, Matsumoto H, Yamadera R, Kubota Y, Otsu A, Suzuki R, Ishitobi H, Mochizuki H, Kojima T, Takano S, Uchida K, Takahashi S, Ema M
- Journal Title
  
  Blood
  
  Volume: 120 Issue: 4 Pages: 914-923
- DOI
  10.1182/blood-2011-12-398156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220009, KAKENHI-PROJECT-22590282, KAKENHI-PROJECT-23500488, KAKENHI-PROJECT-24791634, KAKENHI-PUBLICLY-23122503
[Journal Article] A case of acute adrenal insufficiency unmasked during sunitinib treatment for metastatic renal cell carcinoma2012
- Author(s)
  Yoshino T, Kawai K, Miyazaki J, Kimura T, Ikeda A, Takaoka E, Suetomi T, Oikawa T, Kojima T, Iwasaki H, Shimano H, Nishiyama H
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 42(8) Issue: 8 Pages: 764-6
- DOI
  10.1093/jjco/hys070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791634
[Presentation] Whole blood gene expression profiles correlate with response to a combined therapy with Nivolumab plus Ipilimumab in patients with metastatic renal cell carcinoma2023
- Author(s)
  神鳥周也、小島崇宏　他
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-21K09365
[Presentation] 転移性腎癌における全血遺伝子発現は免疫チェックポイント阻害剤の治療効果を予測する2022
- Author(s)
  南雲義之、小島崇宏　他
- Organizer
  第60回　日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09365
[Presentation] Determination of Circulating tumor DNA alterations in advanced urothelial carcinoma patients treated with pembrolizumab and clinical implications2020
- Author(s)
  Kozaburo Tanuma, Takahiro Kojima, Masanobu Shiga, Shuya Kandori, Tomokazu Kimura, Takashi Kawahara, Hiromitsu Negoro and Hiroyuki Nishiyama
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K09158
[Presentation] Germline TP53 codon72 is associated with FGFR3 and RAS mutation and FGF signals in bladder cancer2018
- Author(s)
  河原貴史、小島崇宏、木村友和、河合弘二、西山博之
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K09158
[Presentation] Antitumor effect of cationic liposome incorporating keto-mycolic acid from Mycobacterium bovis bacillus Calmette-Guerin in mouse model.2018
- Author(s)
  Takayuki Yoshino, Jun Miyazaki, Takahiro Kojima, Shuya Kandori, Hideyuki Akaza, Ikuya Yano, Hiroyuki Nishiyama
- Organizer
  ASCO-GU
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02934

1. Nishiyama Hiroyuki (20324642)

# of Collaborated Projects: 8 results

# of Collaborated Products: 10 results
2. 宮崎淳 (10550246)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
3. 河合弘二 (90272195)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
4. 神鳥周也 (50707825)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
5. 高岡栄一郎 (50625340)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SUETOMI TAKAHIRO (10574650)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. Shimazui Toru (80235613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. Joraku Akira (60436277)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 木村友和 (10633191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Sakata-Yanagimoto Mamiko (80451805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Hoshi Akio (90453711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Matsuzaka Takashi (70400679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. 野口雅之 (00198582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 日下部学 (40804381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 河原貴史 (50758919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. 吉川和宏 (60109759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 松岡妙子 (90781617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松阪諭 (00372665)

# of Collaborated Projects: 1 results

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19. 根来宏光 (80708595)

# of Collaborated Projects: 1 results

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20. 大西洋 (30213804)

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21. 神宮啓一 (00451592)

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22. 白井克幸 (10400748)

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23. 村上祐司 (10403528)

# of Collaborated Projects: 1 results

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24. 淡河悦代 (20204729)

# of Collaborated Projects: 1 results

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25. 小岩井慶一郎 (20419360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 平田岳郎 (20777916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 佐藤啓 (20793532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 櫻井英幸 (50235222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 増井浩二 (20783830)

# of Collaborated Projects: 1 results

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30. 高橋正幸 (50325255)

# of Collaborated Projects: 1 results

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31. 土谷順彦 (70282176)

# of Collaborated Projects: 1 results

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32. 青木昌彦 (70292141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 萬利乃寛 (70372505)

# of Collaborated Projects: 1 results

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34. 山下英臣 (70447407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 室伏景子 (70455236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 古平毅 (80303626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 生島仁史 (90202861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 井垣浩 (90361344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 三井貴彦 (90421966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 猪子誠人 (30393127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. HAYASHI Tetsutaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 羽渕友則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 山崎晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
44. 内田和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 依馬正次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kojima Takahiro 小島 崇宏

KOJIMA Takahiro 小島 崇宏

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前立腺がん患者由来細胞を用いた個別化前臨床モデルの作成と分子機構の解明Principal Investigator

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泌尿器癌における全血RNAを用いた免疫細胞の多様性の理解と治療効果予測への応用Principal Investigator

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Development of novel molecular characterization for urothelial cancer based on genetic and environmental factorsPrincipal Investigator

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The roles of RAC2-VAV1 signaling in oncogenesis and sarcomatoid differentiation of renal cell carcinomaPrincipal Investigator

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Kojima Takahiro 小島崇宏

KOJIMA Takahiro 小島崇宏