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Kusakabe Manabu  日下部 学

Researcher Number 40804381
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-2518-0776
Affiliation (based on the past Project Information) *help 2018 – 2021: 筑波大学, 医学医療系, 講師
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Except Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 50:Oncology and related fields
Keywords
Principal Investigator
シーケンス / 次世代シーケンス / 悪性リンパ腫 / 腫瘍内不均一性 / びまん性大細胞型B細胞リンパ腫 / 予後予測 / メソトレキセート / 自己免疫疾患 / 遺伝子変異 / 医原性リンパ増殖性疾患 … More
Except Principal Investigator
… More 間葉系幹細胞 / 幹細胞ニッチ / 骨髄繊維症 / 骨髄異形成症候群 / 造血器腫瘍 / 造血ニッチ / 急性骨髄性白血病 / 造血幹細胞 / 造血幹細胞ニッチ / 微小環境 / 炎症細胞 / TET2 / メラノーマ / マウスモデル / クローン造血 / がん免疫応答 / がん微小環境 Less
  • Research Projects

    (4 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (17 People)
  •  びまん性大細胞型B細胞リンパ腫の臨床検体シーケンスによる腫瘍内不均一性の解明Principal Investigator

    • Principal Investigator
      日下部 学
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Tsukuba
  •  Tumor-supporting mechanisms by inflammatory cells with somatic mutations

    • Principal Investigator
      Sakata-Yanagimoto Mamiko
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      University of Tsukuba
  •  Analyses of hematopoietic niche in hematologic malignancy

    • Principal Investigator
      Nishikii Hidekazu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Tsukuba
  •  OIIA-LPD and genetic alterationPrincipal Investigator

    • Principal Investigator
      Kusakabe Manabu
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Tsukuba

All 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Intratumor heterogeneity of lymphoma identified by multiregion sequencing of autopsy samples2021

    • Author(s)
      Makishima Kenichi、Suehara Yasuhito、Abe Yoshiaki、Hattori Keiichiro、Kusakabe Manabu、Matsuoka Ryota、Chiba Shigeru、Sakata‐Yanagimoto Mamiko
    • Journal Title

      Cancer Science

      Volume: - Issue: 1 Pages: 362-364

    • DOI

      10.1111/cas.15178

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08725, KAKENHI-PROJECT-20K16165, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-19H03684
  • [Journal Article] Retrospective analyses of other iatrogenic immunodeficiency‐associated lymphoproliferative disorders in patients with rheumatic diseases2021

    • Author(s)
      Kaji D、Kusakabe M、Sakata‐Yanagimoto M、Makishima K、Suehara Y、Hattori K、Ota Y、Mitsuki T、Yuasa M、Kageyama K、Taya Y、Nishida A、Ishiwata K、Takagi S、Yamamoto H、Asano‐Mori Y、Ubara Y、Izutsu K、Uchida N、Wake A、Taniguchi S、Yamamoto G、Chiba S
    • Journal Title

      British Journal of Haematology

      Volume: 195 Issue: 4 Pages: 585-594

    • DOI

      10.1111/bjh.17824

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08725, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-19H03684
  • [Journal Article] Early administration of cyclosporine may reduce the incidence of cytokine release syndrome after HLA-haploidentical hematopoietic stem-cell transplantation with post-transplant cyclophosphamide2021

    • Author(s)
      Kurita Naoki、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Yokoyama Yasuhisa、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Annals of Hematology

      Volume: 100 Issue: 5 Pages: 1295-1301

    • DOI

      10.1007/s00277-021-04439-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-20K08725, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261
  • [Journal Article] Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status.2020

    • Author(s)
      Shrestha R, Sakata-Yanagimoto M, Maie K, Oshima M, Ishihara M, Suehara Y, Fukumoto K,1 Nakajima-Takagi Y, Matsui H, Kato T, Muto H, Sakamoto T, Kusakabe M, Nannya Y, Makishima H, Ueno H, Saiki R, Ogawa S, Chiba K, Shiraishi Y, Miyano S, Mouly E, Bernard OA, Inaba T, Koseki H, Iwama A, Chiba S
    • Journal Title

      Blood Adv.

      Volume: 4(5) Issue: 5 Pages: 845-854

    • DOI

      10.1182/bloodadvances.2019001324

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08334, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-20K08725, KAKENHI-PROJECT-19K23879, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-19H03684
  • [Journal Article] Dasatinib is an effective treatment for angioimmunoblastic T-cell lymphoma.2020

    • Author(s)
      Nguyen TB, Sakata-Yanagimoto M, Fujisawa M, Tanzima Nuhat S, Miyoshi H, Nannya Y, Hashimoto K, Fukumoto K, Bernard OA, Kiyoki Y, Ishitsuka K, Momose H, Sukegawa S, Shinagawa A, Suyama T, Sato Y, Nishikii H, Obara N, Kusakabe M, Yanagimoto S, Ogawa S, Ohshima K, Chiba S.
    • Journal Title

      Cancer Res. 2020.

      Volume: - Issue: 9 Pages: 1875-1884

    • DOI

      10.1158/0008-5472.can-19-2787

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16077, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19J11329, KAKENHI-PROJECT-19H03684
  • [Journal Article] Occurrence of T-cell and NK-cell subsets with less well-recognized phenotypes in peripheral blood submitted for routine flow cytometry analysis2020

    • Author(s)
      Hill Ainsleigh J.、Zhang Chaoran、Kusakabe Manabu、Gowing Kevin、Wang Xuehai、Brinkman Ryan R.、Weng Andrew P.、Craig Jeffrey W.
    • Journal Title

      Cytometry Part B: Clinical Cytometry

      Volume: - Issue: 2 Pages: 1-5

    • DOI

      10.1002/cyto.b.21876

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16076
  • [Journal Article] Single Cell Phenotypic Profiling of 27 DLBCL Cases Reveals Marked Intertumoral and Intratumoral Heterogeneity2019

    • Author(s)
      Nissen MD、Kusakabe M、Wang X、Simkin G、Gracias D、Tyshchenko K、Hill A、Meskas J、Hung S、Chavez EA、Ennishi D、Aoki T、Sarkozy C、Connors JM、Farinha P、Slack GW、Gascoyne RD、Brinkman RR、Scott DW、Steidl C、Weng AP
    • Journal Title

      Cytometry Part A

      Volume: - Issue: 6 Pages: 1-10

    • DOI

      10.1002/cyto.a.23919

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16076
  • [Journal Article] Durable Leukemic Remission and Autologous Marrow Recovery with Random Chromosomal Abnormalities after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia2019

    • Author(s)
      Nishikii Hidekazu、Kurita Naoki、Shinagawa Atsushi、Sakamoto Tatsuhiro、Kusakabe Manabu、Yokoyama Yasuhisa、Kato Takayasu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Nakamura Naoya、Chiba Shigeru
    • Journal Title

      Case Reports in Hematology

      Volume: 2019 Pages: 1-5

    • DOI

      10.1155/2019/9710790

    • NAID

      120007128070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08316, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09946
  • [Journal Article] The prognosis of disseminated intravascular coagulation associated with hematologic malignancy and its response to recombinant human thrombomodulin2019

    • Author(s)
      Kurita Naoki、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Yokoyama Yasuhisa、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Thrombosis Research

      Volume: 173 Pages: 57-64

    • DOI

      10.1016/j.thromres.2018.11.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09946
  • [Journal Article] Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia2019

    • Author(s)
      Kusakabe M、Sun AC、Tyshchenko K、Wong R、Nanda A、Shanna C、Gusscott S、Chavez EA.、Lorzadeh A、Zhu A、Hill A、Hung S、Brown S、Babaian A、Wang X、Holt RA、Steidl C、Karsan A、Humphries RK、Eaves CJ、Hirst M、Weng AP
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41467-019-10510-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16076
  • [Journal Article] Mutations found in cell-free DNAs of patients with malignant lymphoma at remission can derive from clonal hematopoiesis2019

    • Author(s)
      Suehara Y, Sakata-Yanagimoto M, Hattori K, Kusakabe M, Nanmoku T, Sato T, Noguchi M, Chiba S
    • Journal Title

      Cancer Sci

      Volume: 110(10) Issue: 10 Pages: 3375-3381

    • DOI

      10.1111/cas.14176

    • NAID

      120007133006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19464, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-19K23879, KAKENHI-PROJECT-19H03684
  • [Journal Article] Successful management of primary immune thrombocytopenia with romiplostim during open heart surgery in a hemodialysis patient2019

    • Author(s)
      錦井 秀和、栗田 尚樹、日下部 学、横山 泰久、加藤 貴康、坂田(柳元) 麻実子、小原 直、長谷川 雄一、千葉 滋
    • Journal Title

      Rinsho Ketsueki

      Volume: 60 Issue: 1 Pages: 28-32

    • DOI

      10.11406/rinketsu.60.28

    • NAID

      130007590727

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08316, KAKENHI-PROJECT-18K16076
  • [Journal Article] Droplet digital PCR assay and PNA-LNA clamp method for RHOA mutation detection in angioimmunoblastic T-cell lymphoma2018

    • Author(s)
      Tanzima Nuhat S, Sakata-Yanagimoto M, Komori D, Hattori K, Suehara Y, Fukumoto K, Fujisawa M, Kusakabe M, Matsue K, Wakamatsu H, Shimadzu M, Chiba S
    • Journal Title

      Cancer Sci

      Volume: - Issue: 5 Pages: 1682-1689

    • DOI

      10.1111/cas.13557

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02660, KAKENHI-PROJECT-16K15497, KAKENHI-PROJECT-18K16076
  • [Journal Article] Genetic evidence implies that primary and relapsed tumors arise from common precursor cells in primary central nervous system lymphoma2018

    • Author(s)
      Hattori Keiichiro、Sakata-Yanagimoto Mamiko、Kusakabe Manabu、Nanmoku Toru、Suehara Yasuhito、Matsuoka Ryota、Noguchi Masayuki、Yokoyama Yasuhisa、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Obara Naoshi、Takano Shingo、Ishikawa Eiichi、Matsumura Akira、Muratani Masafumi、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 1 Pages: 401-407

    • DOI

      10.1111/cas.13848

    • NAID

      120007128280

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09946, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-16H02660, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-15H05576
  • [Journal Article] Blastic plasmacytoid dendritic cell neoplasm accompanied by chronic myelomonocytic leukemia successfully treated with azacitidine2018

    • Author(s)
      助川 慎一郎、横山 泰久、錦井 秀和、加藤 貴康、日下部 学、栗田 尚樹、小原 直、長谷川 雄一、千葉 滋、坂田(柳元) 麻実子、松岡 亮太、百瀬 春佳、清木 祐介、野口 雅之、中村 直哉、渡辺 玲、藤本 学
    • Journal Title

      Rinsho Ketsueki

      Volume: 59 Issue: 12 Pages: 2567-2573

    • DOI

      10.11406/rinketsu.59.2567

    • NAID

      130007554669

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K16076
  • [Journal Article] High efficacy of eculizumab treatment for fulminant hemolytic anemia in primary cold agglutinin disease2018

    • Author(s)
      Makishima Kenichi、Obara Naoshi、Ishitsuka Kantaro、Sukegawa Shinichiro、Suma Sakurako、Kiyoki Yusuke、Baba Naoko、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Nishikii Hidekazu、Kurita Naoki、Yokoyama Yasuhisa、Sakata-Yanagimoto Mamiko、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Annals of Hematology

      Volume: 98 Issue: 4 Pages: 1031-1032

    • DOI

      10.1007/s00277-018-3521-4

    • NAID

      120007128039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09898
  • [Journal Article] An Unprecedented Case of p190 BCR-ABL Chronic Myeloid Leukemia Diagnosed during Treatment for Multiple Myeloma: A Case Report and Review of the Literature2018

    • Author(s)
      Miki Kosuke、Obara Naoshi、Makishima Kenichi、Sakamoto Tatsuhiro、Kusakabe Manabu、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Yokoyama Yasuhisa、Sakata-Yanagimoto Mamiko、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Case Reports in Hematology

      Volume: 2018 Pages: 1-5

    • DOI

      10.1155/2018/7863943

    • NAID

      120007128268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107
  • [Journal Article] Blastic plasmacytoid dendritic cell neoplasm arising from clonal hematopoiesis2018

    • Author(s)
      Suma Sakurako、Sakata-Yanagimoto Mamiko、Nguyen Tran B.、Hattori Keiichiro、Sato Taiki、Noguchi Masayuki、Nannya Yasuhito、Ogawa Seishi、Watanabe Rei、Fujimoto Manabu、Nakamura Naoya、Kusakabe Manabu、Nishikii Hidekazu、Kato Takayasu、Chiba Shigeru
    • Journal Title

      International Journal of Hematology

      Volume: 108 Issue: 4 Pages: 447-451

    • DOI

      10.1007/s12185-018-2461-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16077
  • [Journal Article] Liquid biopsy for the identification of intravascular large B-cell lymphoma2018

    • Author(s)
      Suehara Yasuhito、Sakata-Yanagimoto Mamiko、et al
    • Journal Title

      Hematologica

      Volume: in press Issue: 6 Pages: e241-e244

    • DOI

      10.3324/haematol.2017.178830

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15497, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09946, KAKENHI-PROJECT-18K07436, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-16H02660
  • [Presentation] The prognosis for OIIA-LPD was favorable regardless of response to immunosuppressant withdrawal2020

    • Author(s)
      Manabu Kusakabe, Daisuke Kaji,Mamiko Sakata-Yanagimoto,Yasuhito Suehara,Keiichiro Hattori,Yasunori Ota,Mitsuhiro Yuasa,Kosei Kageyama,Yuki Taya,Shinsuke Takagi,Hisashi Yamamoto,Yuki Mori,Naoyuki Uchida,Atsushi Wake,Shuichi Taniguchi,Go Yamamoto,Shigeru Chiba
    • Organizer
      第82回 日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08725
  • [Presentation] Targeted sequencing and IgH rearrangement status revealed branching evolution pattern of SMZL and DLBCL2019

    • Author(s)
      Manabu Kusakabe
    • Organizer
      The 10th JSH INTERNATIONAL SYMPOSIUM 2019 in Ise-Shima
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16076
  • 1.  Sakata-Yanagimoto Mamiko (80451805)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  Nishikii Hidekazu (30512834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  野口 雅之 (00198582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  小島 崇宏 (40626892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  加藤 貴康 (20646591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  小原 直 (70422178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  横山 泰久 (70512820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Hattori Keichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  Fujisawa Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  Fukumoto Kota
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  KURITA Naoki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  NANYA Yasuhito
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  千葉 滋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  松井 啓隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  小川 誠司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  佐藤 悠佑
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  坂本 竜弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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